Amino acid dipepetide frequency for Torque teno canis virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.234AlaAla: 15.234 ± 9.578
0.0AlaCys: 0.0 ± 0.0
4.353AlaAsp: 4.353 ± 2.456
2.176AlaGlu: 2.176 ± 2.35
0.0AlaPhe: 0.0 ± 0.0
5.441AlaGly: 5.441 ± 4.151
0.0AlaHis: 0.0 ± 0.0
3.264AlaIle: 3.264 ± 0.745
2.176AlaLys: 2.176 ± 1.228
3.264AlaLeu: 3.264 ± 0.745
3.264AlaMet: 3.264 ± 3.123
0.0AlaAsn: 0.0 ± 0.0
7.617AlaPro: 7.617 ± 0.714
1.088AlaGln: 1.088 ± 0.614
4.353AlaArg: 4.353 ± 1.113
3.264AlaSer: 3.264 ± 1.842
3.264AlaThr: 3.264 ± 1.812
3.264AlaVal: 3.264 ± 1.812
4.353AlaTrp: 4.353 ± 1.34
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.088CysAla: 1.088 ± 0.614
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
4.353CysGly: 4.353 ± 1.34
4.353CysHis: 4.353 ± 4.7
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.088CysLeu: 1.088 ± 0.614
0.0CysMet: 0.0 ± 0.0
2.176CysAsn: 2.176 ± 1.228
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.176CysSer: 2.176 ± 2.35
0.0CysThr: 0.0 ± 0.0
1.088CysVal: 1.088 ± 0.614
1.088CysTrp: 1.088 ± 1.204
1.088CysTyr: 1.088 ± 0.614
0.0CysXaa: 0.0 ± 0.0
Asp
6.529AspAla: 6.529 ± 3.623
1.088AspCys: 1.088 ± 1.204
3.264AspAsp: 3.264 ± 1.812
2.176AspGlu: 2.176 ± 2.35
3.264AspPhe: 3.264 ± 1.842
1.088AspGly: 1.088 ± 0.614
1.088AspHis: 1.088 ± 0.614
2.176AspIle: 2.176 ± 1.228
5.441AspLys: 5.441 ± 3.07
6.529AspLeu: 6.529 ± 2.889
0.0AspMet: 0.0 ± 0.0
1.088AspAsn: 1.088 ± 0.614
6.529AspPro: 6.529 ± 1.3
3.264AspGln: 3.264 ± 0.745
3.264AspArg: 3.264 ± 1.812
5.441AspSer: 5.441 ± 2.71
2.176AspThr: 2.176 ± 1.228
2.176AspVal: 2.176 ± 1.228
4.353AspTrp: 4.353 ± 1.34
2.176AspTyr: 2.176 ± 1.228
0.0AspXaa: 0.0 ± 0.0
Glu
2.176GluAla: 2.176 ± 2.35
2.176GluCys: 2.176 ± 2.35
5.441GluAsp: 5.441 ± 1.903
4.353GluGlu: 4.353 ± 2.456
1.088GluPhe: 1.088 ± 0.614
5.441GluGly: 5.441 ± 1.903
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
0.0GluLys: 0.0 ± 0.0
5.441GluLeu: 5.441 ± 1.903
0.0GluMet: 0.0 ± 0.0
1.088GluAsn: 1.088 ± 0.614
3.264GluPro: 3.264 ± 1.812
1.088GluGln: 1.088 ± 0.614
6.529GluArg: 6.529 ± 4.589
6.529GluSer: 6.529 ± 3.623
4.353GluThr: 4.353 ± 1.581
1.088GluVal: 1.088 ± 1.204
2.176GluTrp: 2.176 ± 1.228
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.088PheAla: 1.088 ± 0.614
0.0PheCys: 0.0 ± 0.0
3.264PheAsp: 3.264 ± 1.812
2.176PheGlu: 2.176 ± 0.791
2.176PhePhe: 2.176 ± 1.228
1.088PheGly: 1.088 ± 0.614
0.0PheHis: 0.0 ± 0.0
1.088PheIle: 1.088 ± 0.614
2.176PheLys: 2.176 ± 1.228
1.088PheLeu: 1.088 ± 0.614
2.176PheMet: 2.176 ± 0.729
1.088PheAsn: 1.088 ± 0.614
2.176PhePro: 2.176 ± 1.228
0.0PheGln: 0.0 ± 0.0
2.176PheArg: 2.176 ± 1.228
1.088PheSer: 1.088 ± 0.614
0.0PheThr: 0.0 ± 0.0
2.176PheVal: 2.176 ± 1.228
1.088PheTrp: 1.088 ± 0.614
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.353GlyAla: 4.353 ± 1.34
1.088GlyCys: 1.088 ± 0.614
4.353GlyAsp: 4.353 ± 1.34
3.264GlyGlu: 3.264 ± 1.812
1.088GlyPhe: 1.088 ± 1.204
9.793GlyGly: 9.793 ± 4.414
0.0GlyHis: 0.0 ± 0.0
2.176GlyIle: 2.176 ± 1.228
5.441GlyLys: 5.441 ± 3.07
6.529GlyLeu: 6.529 ± 1.3
2.176GlyMet: 2.176 ± 1.89
4.353GlyAsn: 4.353 ± 1.113
6.529GlyPro: 6.529 ± 1.3
2.176GlyGln: 2.176 ± 1.228
2.176GlyArg: 2.176 ± 1.228
3.264GlySer: 3.264 ± 1.812
7.617GlyThr: 7.617 ± 1.364
3.264GlyVal: 3.264 ± 1.942
0.0GlyTrp: 0.0 ± 0.0
5.441GlyTyr: 5.441 ± 1.031
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
4.353HisCys: 4.353 ± 4.7
2.176HisAsp: 2.176 ± 2.35
2.176HisGlu: 2.176 ± 2.35
0.0HisPhe: 0.0 ± 0.0
2.176HisGly: 2.176 ± 2.35
0.0HisHis: 0.0 ± 0.0
1.088HisIle: 1.088 ± 0.614
1.088HisLys: 1.088 ± 0.614
4.353HisLeu: 4.353 ± 1.34
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.176HisPro: 2.176 ± 1.228
1.088HisGln: 1.088 ± 0.614
1.088HisArg: 1.088 ± 0.614
1.088HisSer: 1.088 ± 0.614
3.264HisThr: 3.264 ± 1.842
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.088HisTyr: 1.088 ± 0.614
0.0HisXaa: 0.0 ± 0.0
Ile
4.353IleAla: 4.353 ± 2.456
0.0IleCys: 0.0 ± 0.0
1.088IleAsp: 1.088 ± 0.614
1.088IleGlu: 1.088 ± 0.614
1.088IlePhe: 1.088 ± 0.614
0.0IleGly: 0.0 ± 0.0
1.088IleHis: 1.088 ± 0.614
0.0IleIle: 0.0 ± 0.0
2.176IleLys: 2.176 ± 1.228
2.176IleLeu: 2.176 ± 1.228
3.264IleMet: 3.264 ± 1.842
2.176IleAsn: 2.176 ± 1.228
3.264IlePro: 3.264 ± 1.842
1.088IleGln: 1.088 ± 0.614
2.176IleArg: 2.176 ± 0.791
3.264IleSer: 3.264 ± 1.842
2.176IleThr: 2.176 ± 1.228
2.176IleVal: 2.176 ± 1.228
1.088IleTrp: 1.088 ± 0.614
2.176IleTyr: 2.176 ± 1.228
0.0IleXaa: 0.0 ± 0.0
Lys
2.176LysAla: 2.176 ± 2.35
0.0LysCys: 0.0 ± 0.0
3.264LysAsp: 3.264 ± 0.745
1.088LysGlu: 1.088 ± 0.614
0.0LysPhe: 0.0 ± 0.0
4.353LysGly: 4.353 ± 1.113
1.088LysHis: 1.088 ± 0.614
2.176LysIle: 2.176 ± 1.228
7.617LysLys: 7.617 ± 1.364
2.176LysLeu: 2.176 ± 1.228
0.0LysMet: 0.0 ± 0.571
1.088LysAsn: 1.088 ± 0.614
5.441LysPro: 5.441 ± 3.07
4.353LysGln: 4.353 ± 1.34
5.441LysArg: 5.441 ± 1.903
3.264LysSer: 3.264 ± 3.123
2.176LysThr: 2.176 ± 0.791
2.176LysVal: 2.176 ± 1.228
5.441LysTrp: 5.441 ± 3.07
2.176LysTyr: 2.176 ± 1.228
0.0LysXaa: 0.0 ± 0.0
Leu
6.529LeuAla: 6.529 ± 1.3
2.176LeuCys: 2.176 ± 1.228
4.353LeuAsp: 4.353 ± 1.113
3.264LeuGlu: 3.264 ± 1.942
1.088LeuPhe: 1.088 ± 0.614
5.441LeuGly: 5.441 ± 1.636
0.0LeuHis: 0.0 ± 0.0
1.088LeuIle: 1.088 ± 0.614
6.529LeuLys: 6.529 ± 1.042
6.529LeuLeu: 6.529 ± 2.206
2.176LeuMet: 2.176 ± 1.228
0.0LeuAsn: 0.0 ± 0.0
2.176LeuPro: 2.176 ± 0.791
1.088LeuGln: 1.088 ± 0.614
2.176LeuArg: 2.176 ± 1.228
3.264LeuSer: 3.264 ± 1.842
4.353LeuThr: 4.353 ± 1.581
7.617LeuVal: 7.617 ± 4.211
3.264LeuTrp: 3.264 ± 1.812
2.176LeuTyr: 2.176 ± 0.791
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
1.088MetAsp: 1.088 ± 0.614
1.088MetGlu: 1.088 ± 0.614
0.0MetPhe: 0.0 ± 0.0
1.088MetGly: 1.088 ± 0.614
1.088MetHis: 1.088 ± 0.614
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
5.441MetLeu: 5.441 ± 1.903
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
1.088MetGln: 1.088 ± 0.614
1.088MetArg: 1.088 ± 0.614
3.264MetSer: 3.264 ± 1.812
3.264MetThr: 3.264 ± 0.745
0.0MetVal: 0.0 ± 0.0
1.088MetTrp: 1.088 ± 1.204
1.088MetTyr: 1.088 ± 0.614
0.0MetXaa: 0.0 ± 0.0
Asn
1.088AsnAla: 1.088 ± 0.614
0.0AsnCys: 0.0 ± 0.0
1.088AsnAsp: 1.088 ± 1.204
0.0AsnGlu: 0.0 ± 0.0
1.088AsnPhe: 1.088 ± 0.614
1.088AsnGly: 1.088 ± 0.614
0.0AsnHis: 0.0 ± 0.0
1.088AsnIle: 1.088 ± 0.614
1.088AsnLys: 1.088 ± 0.614
1.088AsnLeu: 1.088 ± 0.614
0.0AsnMet: 0.0 ± 0.0
1.088AsnAsn: 1.088 ± 0.614
5.441AsnPro: 5.441 ± 3.07
1.088AsnGln: 1.088 ± 0.614
4.353AsnArg: 4.353 ± 3.133
2.176AsnSer: 2.176 ± 1.228
3.264AsnThr: 3.264 ± 1.842
1.088AsnVal: 1.088 ± 0.614
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
6.529ProAla: 6.529 ± 1.3
2.176ProCys: 2.176 ± 1.228
2.176ProAsp: 2.176 ± 2.35
6.529ProGlu: 6.529 ± 1.49
3.264ProPhe: 3.264 ± 0.745
9.793ProGly: 9.793 ± 3.064
1.088ProHis: 1.088 ± 0.614
2.176ProIle: 2.176 ± 1.228
4.353ProLys: 4.353 ± 1.113
2.176ProLeu: 2.176 ± 0.791
1.088ProMet: 1.088 ± 0.614
3.264ProAsn: 3.264 ± 1.842
8.705ProPro: 8.705 ± 2.11
3.264ProGln: 3.264 ± 0.745
9.793ProArg: 9.793 ± 2.235
1.088ProSer: 1.088 ± 1.204
5.441ProThr: 5.441 ± 1.903
0.0ProVal: 0.0 ± 0.0
4.353ProTrp: 4.353 ± 1.34
2.176ProTyr: 2.176 ± 1.228
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
2.176GlnAsp: 2.176 ± 1.228
0.0GlnGlu: 0.0 ± 0.0
1.088GlnPhe: 1.088 ± 0.614
2.176GlnGly: 2.176 ± 1.228
5.441GlnHis: 5.441 ± 4.151
5.441GlnIle: 5.441 ± 3.07
0.0GlnLys: 0.0 ± 0.0
1.088GlnLeu: 1.088 ± 0.614
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
4.353GlnPro: 4.353 ± 1.581
2.176GlnGln: 2.176 ± 1.228
1.088GlnArg: 1.088 ± 0.614
4.353GlnSer: 4.353 ± 1.581
2.176GlnThr: 2.176 ± 0.791
1.088GlnVal: 1.088 ± 0.614
2.176GlnTrp: 2.176 ± 1.228
3.264GlnTyr: 3.264 ± 0.745
0.0GlnXaa: 0.0 ± 0.0
Arg
5.441ArgAla: 5.441 ± 1.408
0.0ArgCys: 0.0 ± 0.0
4.353ArgAsp: 4.353 ± 3.133
9.793ArgGlu: 9.793 ± 6.549
1.088ArgPhe: 1.088 ± 0.614
4.353ArgGly: 4.353 ± 1.113
3.264ArgHis: 3.264 ± 1.812
2.176ArgIle: 2.176 ± 1.228
3.264ArgLys: 3.264 ± 0.745
3.264ArgLeu: 3.264 ± 1.842
0.0ArgMet: 0.0 ± 0.0
3.264ArgAsn: 3.264 ± 1.942
4.353ArgPro: 4.353 ± 1.581
5.441ArgGln: 5.441 ± 1.636
26.115ArgArg: 26.115 ± 6.678
2.176ArgSer: 2.176 ± 1.228
1.088ArgThr: 1.088 ± 1.204
1.088ArgVal: 1.088 ± 0.614
6.529ArgTrp: 6.529 ± 1.042
4.353ArgTyr: 4.353 ± 2.456
0.0ArgXaa: 0.0 ± 0.0
Ser
4.353SerAla: 4.353 ± 1.34
0.0SerCys: 0.0 ± 0.0
4.353SerAsp: 4.353 ± 2.512
4.353SerGlu: 4.353 ± 1.581
4.353SerPhe: 4.353 ± 1.34
5.441SerGly: 5.441 ± 4.151
4.353SerHis: 4.353 ± 1.34
3.264SerIle: 3.264 ± 1.842
3.264SerLys: 3.264 ± 1.812
2.176SerLeu: 2.176 ± 0.791
1.088SerMet: 1.088 ± 0.614
2.176SerAsn: 2.176 ± 0.791
3.264SerPro: 3.264 ± 1.812
2.176SerGln: 2.176 ± 0.791
1.088SerArg: 1.088 ± 0.614
8.705SerSer: 8.705 ± 3.163
8.705SerThr: 8.705 ± 2.226
0.0SerVal: 0.0 ± 0.0
5.441SerTrp: 5.441 ± 1.903
3.264SerTyr: 3.264 ± 1.942
0.0SerXaa: 0.0 ± 0.0
Thr
3.264ThrAla: 3.264 ± 0.745
1.088ThrCys: 1.088 ± 0.614
5.441ThrAsp: 5.441 ± 3.07
5.441ThrGlu: 5.441 ± 1.031
0.0ThrPhe: 0.0 ± 0.0
4.353ThrGly: 4.353 ± 1.113
3.264ThrHis: 3.264 ± 1.842
2.176ThrIle: 2.176 ± 1.228
3.264ThrLys: 3.264 ± 0.745
5.441ThrLeu: 5.441 ± 1.408
0.0ThrMet: 0.0 ± 0.0
1.088ThrAsn: 1.088 ± 0.614
8.705ThrPro: 8.705 ± 3.411
4.353ThrGln: 4.353 ± 2.512
5.441ThrArg: 5.441 ± 1.903
4.353ThrSer: 4.353 ± 3.133
7.617ThrThr: 7.617 ± 5.726
0.0ThrVal: 0.0 ± 0.0
1.088ThrTrp: 1.088 ± 0.614
2.176ThrTyr: 2.176 ± 1.228
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
4.353ValAsp: 4.353 ± 1.34
3.264ValGlu: 3.264 ± 3.123
1.088ValPhe: 1.088 ± 0.614
2.176ValGly: 2.176 ± 1.228
0.0ValHis: 0.0 ± 0.0
2.176ValIle: 2.176 ± 1.228
2.176ValLys: 2.176 ± 1.228
1.088ValLeu: 1.088 ± 0.614
2.176ValMet: 2.176 ± 1.228
0.0ValAsn: 0.0 ± 0.0
1.088ValPro: 1.088 ± 1.204
0.0ValGln: 0.0 ± 0.0
2.176ValArg: 2.176 ± 1.228
4.353ValSer: 4.353 ± 2.512
1.088ValThr: 1.088 ± 1.204
0.0ValVal: 0.0 ± 0.0
2.176ValTrp: 2.176 ± 1.228
1.088ValTyr: 1.088 ± 0.614
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
4.353TrpCys: 4.353 ± 1.34
2.176TrpAsp: 2.176 ± 1.228
0.0TrpGlu: 0.0 ± 0.0
2.176TrpPhe: 2.176 ± 1.228
4.353TrpGly: 4.353 ± 2.456
0.0TrpHis: 0.0 ± 0.0
1.088TrpIle: 1.088 ± 0.614
5.441TrpLys: 5.441 ± 5.394
3.264TrpLeu: 3.264 ± 1.842
1.088TrpMet: 1.088 ± 1.204
2.176TrpAsn: 2.176 ± 1.228
3.264TrpPro: 3.264 ± 0.745
1.088TrpGln: 1.088 ± 0.614
3.264TrpArg: 3.264 ± 1.842
6.529TrpSer: 6.529 ± 3.623
4.353TrpThr: 4.353 ± 1.34
1.088TrpVal: 1.088 ± 0.614
1.088TrpTrp: 1.088 ± 0.614
2.176TrpTyr: 2.176 ± 1.228
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.176TyrAla: 2.176 ± 1.228
0.0TyrCys: 0.0 ± 0.0
4.353TyrAsp: 4.353 ± 2.456
0.0TyrGlu: 0.0 ± 0.0
2.176TyrPhe: 2.176 ± 1.228
1.088TyrGly: 1.088 ± 0.614
1.088TyrHis: 1.088 ± 0.614
3.264TyrIle: 3.264 ± 1.842
1.088TyrLys: 1.088 ± 1.204
1.088TyrLeu: 1.088 ± 0.614
1.088TyrMet: 1.088 ± 0.614
0.0TyrAsn: 0.0 ± 0.0
1.088TyrPro: 1.088 ± 0.614
2.176TyrGln: 2.176 ± 0.791
7.617TyrArg: 7.617 ± 0.714
2.176TyrSer: 2.176 ± 1.228
2.176TyrThr: 2.176 ± 0.791
1.088TyrVal: 1.088 ± 0.614
2.176TyrTrp: 2.176 ± 1.228
3.264TyrTyr: 3.264 ± 1.842
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (920 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski