Amino acid dipepetide frequency for Bovine parainfluenza 3 virus (BPIV-3)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.913AlaAla: 2.913 ± 0.576
0.208AlaCys: 0.208 ± 0.131
1.665AlaAsp: 1.665 ± 0.423
2.081AlaGlu: 2.081 ± 0.716
2.289AlaPhe: 2.289 ± 0.707
2.289AlaGly: 2.289 ± 1.056
0.624AlaHis: 0.624 ± 0.392
5.41AlaIle: 5.41 ± 0.799
3.745AlaLys: 3.745 ± 0.544
5.826AlaLeu: 5.826 ± 1.399
1.248AlaMet: 1.248 ± 0.578
2.289AlaAsn: 2.289 ± 0.428
1.04AlaPro: 1.04 ± 0.629
2.289AlaGln: 2.289 ± 0.711
1.04AlaArg: 1.04 ± 0.735
4.161AlaSer: 4.161 ± 1.011
3.537AlaThr: 3.537 ± 1.053
2.705AlaVal: 2.705 ± 1.078
0.208AlaTrp: 0.208 ± 0.288
1.665AlaTyr: 1.665 ± 0.538
0.0AlaXaa: 0.0 ± 0.0
Cys
0.208CysAla: 0.208 ± 0.131
0.416CysCys: 0.416 ± 0.261
0.832CysAsp: 0.832 ± 0.523
0.624CysGlu: 0.624 ± 0.281
0.624CysPhe: 0.624 ± 0.256
0.624CysGly: 0.624 ± 0.293
0.416CysHis: 0.416 ± 0.261
1.248CysIle: 1.248 ± 0.915
0.416CysLys: 0.416 ± 0.431
1.457CysLeu: 1.457 ± 0.332
0.0CysMet: 0.0 ± 0.0
1.457CysAsn: 1.457 ± 0.592
1.248CysPro: 1.248 ± 0.816
0.832CysGln: 0.832 ± 0.566
0.208CysArg: 0.208 ± 0.131
1.04CysSer: 1.04 ± 0.429
1.457CysThr: 1.457 ± 0.35
0.624CysVal: 0.624 ± 0.261
0.0CysTrp: 0.0 ± 0.0
0.624CysTyr: 0.624 ± 0.317
0.0CysXaa: 0.0 ± 0.0
Asp
2.497AspAla: 2.497 ± 1.056
0.624AspCys: 0.624 ± 0.362
4.786AspAsp: 4.786 ± 0.718
4.37AspGlu: 4.37 ± 1.097
0.208AspPhe: 0.208 ± 0.247
2.289AspGly: 2.289 ± 0.549
0.624AspHis: 0.624 ± 0.261
5.618AspIle: 5.618 ± 1.084
3.953AspLys: 3.953 ± 0.752
5.618AspLeu: 5.618 ± 0.449
1.665AspMet: 1.665 ± 0.8
3.537AspAsn: 3.537 ± 0.719
4.578AspPro: 4.578 ± 0.849
2.497AspGln: 2.497 ± 0.948
2.497AspArg: 2.497 ± 0.553
5.202AspSer: 5.202 ± 0.391
4.37AspThr: 4.37 ± 0.793
3.329AspVal: 3.329 ± 0.733
0.624AspTrp: 0.624 ± 0.289
2.497AspTyr: 2.497 ± 0.749
0.0AspXaa: 0.0 ± 0.0
Glu
2.497GluAla: 2.497 ± 0.88
1.04GluCys: 1.04 ± 0.514
3.537GluAsp: 3.537 ± 0.966
3.329GluGlu: 3.329 ± 1.338
2.705GluPhe: 2.705 ± 1.016
3.121GluGly: 3.121 ± 0.8
1.04GluHis: 1.04 ± 0.478
4.994GluIle: 4.994 ± 0.751
4.37GluLys: 4.37 ± 1.213
7.074GluLeu: 7.074 ± 0.852
2.289GluMet: 2.289 ± 0.818
2.705GluAsn: 2.705 ± 0.44
1.665GluPro: 1.665 ± 0.28
1.457GluGln: 1.457 ± 1.044
1.873GluArg: 1.873 ± 0.934
4.786GluSer: 4.786 ± 1.504
4.994GluThr: 4.994 ± 1.1
2.289GluVal: 2.289 ± 0.455
0.832GluTrp: 0.832 ± 0.361
1.457GluTyr: 1.457 ± 0.307
0.0GluXaa: 0.0 ± 0.0
Phe
1.248PheAla: 1.248 ± 0.488
0.416PheCys: 0.416 ± 0.261
2.081PheAsp: 2.081 ± 0.132
1.248PheGlu: 1.248 ± 0.39
1.457PhePhe: 1.457 ± 0.497
3.121PheGly: 3.121 ± 0.892
0.624PheHis: 0.624 ± 0.304
3.329PheIle: 3.329 ± 0.944
2.081PheLys: 2.081 ± 0.592
3.329PheLeu: 3.329 ± 0.571
0.416PheMet: 0.416 ± 0.28
1.665PheAsn: 1.665 ± 0.395
1.04PhePro: 1.04 ± 0.497
1.248PheGln: 1.248 ± 0.488
1.457PheArg: 1.457 ± 0.601
1.665PheSer: 1.665 ± 0.466
1.665PheThr: 1.665 ± 0.425
0.832PheVal: 0.832 ± 0.271
1.04PheTrp: 1.04 ± 0.429
0.208PheTyr: 0.208 ± 0.131
0.0PheXaa: 0.0 ± 0.0
Gly
2.289GlyAla: 2.289 ± 0.775
1.04GlyCys: 1.04 ± 0.882
2.705GlyAsp: 2.705 ± 0.521
2.081GlyGlu: 2.081 ± 0.459
1.665GlyPhe: 1.665 ± 0.485
4.994GlyGly: 4.994 ± 0.964
1.04GlyHis: 1.04 ± 0.311
6.658GlyIle: 6.658 ± 1.653
3.121GlyLys: 3.121 ± 0.653
5.826GlyLeu: 5.826 ± 0.591
1.248GlyMet: 1.248 ± 0.295
3.745GlyAsn: 3.745 ± 0.642
2.289GlyPro: 2.289 ± 0.741
0.832GlyGln: 0.832 ± 0.514
3.745GlyArg: 3.745 ± 1.314
4.786GlySer: 4.786 ± 1.772
2.081GlyThr: 2.081 ± 1.225
3.537GlyVal: 3.537 ± 0.634
0.0GlyTrp: 0.0 ± 0.0
2.289GlyTyr: 2.289 ± 0.84
0.0GlyXaa: 0.0 ± 0.0
His
1.04HisAla: 1.04 ± 0.531
0.416HisCys: 0.416 ± 0.261
1.04HisAsp: 1.04 ± 0.311
1.457HisGlu: 1.457 ± 0.557
0.0HisPhe: 0.0 ± 0.0
0.832HisGly: 0.832 ± 0.352
0.208HisHis: 0.208 ± 0.28
1.248HisIle: 1.248 ± 0.508
0.624HisLys: 0.624 ± 0.281
2.081HisLeu: 2.081 ± 0.745
0.208HisMet: 0.208 ± 0.288
0.624HisAsn: 0.624 ± 0.256
1.04HisPro: 1.04 ± 0.465
0.416HisGln: 0.416 ± 0.261
0.832HisArg: 0.832 ± 0.462
1.665HisSer: 1.665 ± 0.567
1.457HisThr: 1.457 ± 0.434
0.832HisVal: 0.832 ± 0.43
0.208HisTrp: 0.208 ± 0.131
0.624HisTyr: 0.624 ± 0.315
0.0HisXaa: 0.0 ± 0.0
Ile
4.161IleAla: 4.161 ± 1.559
1.665IleCys: 1.665 ± 0.266
4.786IleAsp: 4.786 ± 1.651
5.41IleGlu: 5.41 ± 1.505
2.497IlePhe: 2.497 ± 0.506
4.994IleGly: 4.994 ± 0.646
0.416IleHis: 0.416 ± 0.261
9.363IleIle: 9.363 ± 2.235
7.283IleLys: 7.283 ± 1.647
6.034IleLeu: 6.034 ± 0.619
2.289IleMet: 2.289 ± 0.677
5.826IleAsn: 5.826 ± 0.937
4.161IlePro: 4.161 ± 1.169
3.329IleGln: 3.329 ± 1.116
4.786IleArg: 4.786 ± 1.048
8.323IleSer: 8.323 ± 1.556
8.947IleThr: 8.947 ± 2.223
4.37IleVal: 4.37 ± 1.899
0.832IleTrp: 0.832 ± 0.352
3.953IleTyr: 3.953 ± 0.666
0.0IleXaa: 0.0 ± 0.0
Lys
3.745LysAla: 3.745 ± 0.645
0.416LysCys: 0.416 ± 0.261
4.786LysAsp: 4.786 ± 1.159
4.37LysGlu: 4.37 ± 1.293
2.497LysPhe: 2.497 ± 0.887
3.329LysGly: 3.329 ± 1.021
0.624LysHis: 0.624 ± 0.431
5.41LysIle: 5.41 ± 1.185
3.329LysLys: 3.329 ± 1.174
6.45LysLeu: 6.45 ± 1.645
2.081LysMet: 2.081 ± 0.557
4.994LysAsn: 4.994 ± 1.512
1.457LysPro: 1.457 ± 0.513
2.289LysGln: 2.289 ± 0.786
3.745LysArg: 3.745 ± 0.548
4.994LysSer: 4.994 ± 0.384
3.745LysThr: 3.745 ± 0.38
3.329LysVal: 3.329 ± 0.739
0.416LysTrp: 0.416 ± 0.261
3.329LysTyr: 3.329 ± 0.672
0.0LysXaa: 0.0 ± 0.0
Leu
5.826LeuAla: 5.826 ± 1.175
0.624LeuCys: 0.624 ± 0.425
7.491LeuAsp: 7.491 ± 1.473
4.578LeuGlu: 4.578 ± 1.14
3.953LeuPhe: 3.953 ± 0.837
5.41LeuGly: 5.41 ± 0.885
1.04LeuHis: 1.04 ± 0.654
8.323LeuIle: 8.323 ± 0.869
7.491LeuLys: 7.491 ± 2.503
7.907LeuLeu: 7.907 ± 1.151
2.913LeuMet: 2.913 ± 0.766
6.45LeuAsn: 6.45 ± 0.69
3.537LeuPro: 3.537 ± 1.202
3.537LeuGln: 3.537 ± 1.31
4.161LeuArg: 4.161 ± 0.941
8.739LeuSer: 8.739 ± 1.546
5.41LeuThr: 5.41 ± 1.435
4.786LeuVal: 4.786 ± 0.933
0.832LeuTrp: 0.832 ± 0.367
3.745LeuTyr: 3.745 ± 0.417
0.0LeuXaa: 0.0 ± 0.0
Met
1.04MetAla: 1.04 ± 0.865
0.208MetCys: 0.208 ± 0.131
1.873MetAsp: 1.873 ± 1.182
2.913MetGlu: 2.913 ± 0.703
1.04MetPhe: 1.04 ± 0.486
0.208MetGly: 0.208 ± 0.288
0.624MetHis: 0.624 ± 0.256
2.705MetIle: 2.705 ± 0.646
1.248MetLys: 1.248 ± 0.407
1.873MetLeu: 1.873 ± 0.516
0.0MetMet: 0.0 ± 0.0
0.832MetAsn: 0.832 ± 0.367
0.208MetPro: 0.208 ± 0.131
0.416MetGln: 0.416 ± 0.257
2.289MetArg: 2.289 ± 0.226
2.081MetSer: 2.081 ± 0.459
1.665MetThr: 1.665 ± 0.197
1.665MetVal: 1.665 ± 0.475
0.208MetTrp: 0.208 ± 0.131
1.04MetTyr: 1.04 ± 0.497
0.0MetXaa: 0.0 ± 0.0
Asn
2.705AsnAla: 2.705 ± 0.554
1.248AsnCys: 1.248 ± 0.658
4.37AsnAsp: 4.37 ± 0.937
4.578AsnGlu: 4.578 ± 0.823
0.624AsnPhe: 0.624 ± 0.293
3.953AsnGly: 3.953 ± 0.885
1.457AsnHis: 1.457 ± 0.801
7.699AsnIle: 7.699 ± 0.932
3.953AsnLys: 3.953 ± 0.782
5.41AsnLeu: 5.41 ± 1.409
0.832AsnMet: 0.832 ± 0.442
4.578AsnAsn: 4.578 ± 1.098
3.745AsnPro: 3.745 ± 0.721
3.953AsnGln: 3.953 ± 0.847
2.289AsnArg: 2.289 ± 0.978
3.537AsnSer: 3.537 ± 0.639
3.953AsnThr: 3.953 ± 1.51
1.873AsnVal: 1.873 ± 0.569
1.04AsnTrp: 1.04 ± 0.478
3.121AsnTyr: 3.121 ± 0.817
0.0AsnXaa: 0.0 ± 0.0
Pro
2.081ProAla: 2.081 ± 0.487
0.0ProCys: 0.0 ± 0.0
2.705ProAsp: 2.705 ± 0.324
3.329ProGlu: 3.329 ± 0.882
0.416ProPhe: 0.416 ± 0.257
2.705ProGly: 2.705 ± 1.074
0.832ProHis: 0.832 ± 0.54
1.665ProIle: 1.665 ± 0.567
2.705ProLys: 2.705 ± 0.81
3.953ProLeu: 3.953 ± 1.226
0.624ProMet: 0.624 ± 0.362
2.913ProAsn: 2.913 ± 0.944
1.248ProPro: 1.248 ± 0.468
1.665ProGln: 1.665 ± 0.614
2.497ProArg: 2.497 ± 1.251
3.537ProSer: 3.537 ± 0.983
1.457ProThr: 1.457 ± 0.277
1.248ProVal: 1.248 ± 0.381
0.624ProTrp: 0.624 ± 0.488
2.081ProTyr: 2.081 ± 0.376
0.0ProXaa: 0.0 ± 0.0
Gln
1.457GlnAla: 1.457 ± 0.263
0.416GlnCys: 0.416 ± 0.363
1.665GlnAsp: 1.665 ± 0.747
2.705GlnGlu: 2.705 ± 0.787
0.208GlnPhe: 0.208 ± 0.131
2.289GlnGly: 2.289 ± 1.274
0.624GlnHis: 0.624 ± 0.338
4.786GlnIle: 4.786 ± 1.096
2.913GlnLys: 2.913 ± 0.512
2.913GlnLeu: 2.913 ± 0.435
1.457GlnMet: 1.457 ± 0.306
3.329GlnAsn: 3.329 ± 1.158
1.248GlnPro: 1.248 ± 0.598
1.457GlnGln: 1.457 ± 0.593
1.873GlnArg: 1.873 ± 0.503
3.953GlnSer: 3.953 ± 1.486
1.873GlnThr: 1.873 ± 0.771
1.457GlnVal: 1.457 ± 0.35
0.208GlnTrp: 0.208 ± 0.131
1.457GlnTyr: 1.457 ± 0.519
0.0GlnXaa: 0.0 ± 0.0
Arg
2.081ArgAla: 2.081 ± 0.583
0.832ArgCys: 0.832 ± 0.361
2.705ArgAsp: 2.705 ± 0.924
2.289ArgGlu: 2.289 ± 0.179
1.873ArgPhe: 1.873 ± 0.441
2.497ArgGly: 2.497 ± 0.842
1.04ArgHis: 1.04 ± 0.465
3.537ArgIle: 3.537 ± 0.866
3.121ArgLys: 3.121 ± 1.012
6.242ArgLeu: 6.242 ± 0.321
1.04ArgMet: 1.04 ± 0.47
2.289ArgAsn: 2.289 ± 0.462
1.04ArgPro: 1.04 ± 0.473
2.497ArgGln: 2.497 ± 0.96
2.289ArgArg: 2.289 ± 0.596
3.537ArgSer: 3.537 ± 1.276
2.289ArgThr: 2.289 ± 0.436
3.121ArgVal: 3.121 ± 0.792
0.416ArgTrp: 0.416 ± 0.248
2.081ArgTyr: 2.081 ± 0.795
0.0ArgXaa: 0.0 ± 0.0
Ser
2.913SerAla: 2.913 ± 0.948
1.665SerCys: 1.665 ± 0.416
4.37SerAsp: 4.37 ± 0.873
3.745SerGlu: 3.745 ± 0.897
2.289SerPhe: 2.289 ± 0.648
4.578SerGly: 4.578 ± 0.668
2.081SerHis: 2.081 ± 0.376
7.699SerIle: 7.699 ± 1.865
4.786SerLys: 4.786 ± 1.131
9.571SerLeu: 9.571 ± 0.668
1.248SerMet: 1.248 ± 0.535
6.866SerAsn: 6.866 ± 0.88
1.873SerPro: 1.873 ± 0.535
2.289SerGln: 2.289 ± 0.491
4.161SerArg: 4.161 ± 0.875
6.45SerSer: 6.45 ± 1.801
6.658SerThr: 6.658 ± 1.294
3.953SerVal: 3.953 ± 0.669
1.457SerTrp: 1.457 ± 0.642
2.705SerTyr: 2.705 ± 0.269
0.0SerXaa: 0.0 ± 0.0
Thr
3.745ThrAla: 3.745 ± 0.894
1.04ThrCys: 1.04 ± 0.514
3.329ThrAsp: 3.329 ± 0.713
4.786ThrGlu: 4.786 ± 1.312
2.289ThrPhe: 2.289 ± 0.773
3.953ThrGly: 3.953 ± 0.996
1.04ThrHis: 1.04 ± 0.542
6.45ThrIle: 6.45 ± 1.04
2.913ThrLys: 2.913 ± 1.229
6.242ThrLeu: 6.242 ± 0.886
1.457ThrMet: 1.457 ± 0.57
4.161ThrAsn: 4.161 ± 2.113
1.873ThrPro: 1.873 ± 0.441
3.537ThrGln: 3.537 ± 1.113
3.329ThrArg: 3.329 ± 0.67
5.826ThrSer: 5.826 ± 1.545
5.618ThrThr: 5.618 ± 1.28
3.329ThrVal: 3.329 ± 0.479
1.04ThrTrp: 1.04 ± 0.478
1.873ThrTyr: 1.873 ± 0.768
0.0ThrXaa: 0.0 ± 0.0
Val
2.081ValAla: 2.081 ± 0.878
0.832ValCys: 0.832 ± 0.367
2.497ValAsp: 2.497 ± 0.925
2.289ValGlu: 2.289 ± 0.404
2.289ValPhe: 2.289 ± 0.778
2.497ValGly: 2.497 ± 0.618
1.873ValHis: 1.873 ± 0.722
3.745ValIle: 3.745 ± 1.184
3.953ValLys: 3.953 ± 0.701
4.994ValLeu: 4.994 ± 1.414
1.04ValMet: 1.04 ± 0.465
3.745ValAsn: 3.745 ± 0.813
2.289ValPro: 2.289 ± 0.753
2.081ValGln: 2.081 ± 0.542
1.873ValArg: 1.873 ± 0.469
3.537ValSer: 3.537 ± 0.453
2.705ValThr: 2.705 ± 0.449
3.121ValVal: 3.121 ± 0.463
0.208ValTrp: 0.208 ± 0.197
1.457ValTyr: 1.457 ± 0.384
0.0ValXaa: 0.0 ± 0.0
Trp
0.832TrpAla: 0.832 ± 0.352
0.0TrpCys: 0.0 ± 0.0
1.248TrpAsp: 1.248 ± 0.579
0.416TrpGlu: 0.416 ± 0.218
0.624TrpPhe: 0.624 ± 0.256
0.624TrpGly: 0.624 ± 0.362
0.416TrpHis: 0.416 ± 0.394
1.248TrpIle: 1.248 ± 0.408
0.208TrpLys: 0.208 ± 0.197
0.832TrpLeu: 0.832 ± 0.523
1.04TrpMet: 1.04 ± 0.47
0.208TrpAsn: 0.208 ± 0.131
0.208TrpPro: 0.208 ± 0.131
0.0TrpGln: 0.0 ± 0.0
0.624TrpArg: 0.624 ± 0.256
1.04TrpSer: 1.04 ± 0.382
1.04TrpThr: 1.04 ± 0.572
0.208TrpVal: 0.208 ± 0.131
0.0TrpTrp: 0.0 ± 0.0
0.624TrpTyr: 0.624 ± 0.513
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.873TyrAla: 1.873 ± 0.907
1.248TyrCys: 1.248 ± 0.445
2.913TyrAsp: 2.913 ± 0.928
1.457TyrGlu: 1.457 ± 0.484
0.624TyrPhe: 0.624 ± 0.392
1.665TyrGly: 1.665 ± 0.504
0.208TyrHis: 0.208 ± 0.131
2.289TyrIle: 2.289 ± 0.43
3.121TyrLys: 3.121 ± 0.881
3.121TyrLeu: 3.121 ± 0.985
0.832TyrMet: 0.832 ± 0.367
2.913TyrAsn: 2.913 ± 1.144
2.497TyrPro: 2.497 ± 0.853
1.665TyrGln: 1.665 ± 0.47
1.248TyrArg: 1.248 ± 0.404
2.497TyrSer: 2.497 ± 0.647
2.913TyrThr: 2.913 ± 1.02
2.497TyrVal: 2.497 ± 0.816
1.248TyrTrp: 1.248 ± 0.512
1.457TyrTyr: 1.457 ± 0.549
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (4807 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski