Amino acid dipepetide frequency for Pipra filicauda (Wire-tailed manakin)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.487AlaAla: 7.487 ± 0.037	1.246AlaCys: 1.246 ± 0.009	3.079AlaAsp: 3.079 ± 0.014	5.358AlaGlu: 5.358 ± 0.029	2.349AlaPhe: 2.349 ± 0.012	4.795AlaGly: 4.795 ± 0.021	1.382AlaHis: 1.382 ± 0.009	2.686AlaIle: 2.686 ± 0.014	3.683AlaLys: 3.683 ± 0.023	6.879AlaLeu: 6.879 ± 0.025	1.528AlaMet: 1.528 ± 0.01	2.182AlaAsn: 2.182 ± 0.011	3.975AlaPro: 3.975 ± 0.027	3.257AlaGln: 3.257 ± 0.018	3.536AlaArg: 3.536 ± 0.019	5.594AlaSer: 5.594 ± 0.02	3.488AlaThr: 3.488 ± 0.017	4.957AlaVal: 4.957 ± 0.017	0.727AlaTrp: 0.727 ± 0.007	1.394AlaTyr: 1.394 ± 0.01	0.002AlaXaa: 0.002 ± 0.0
Cys	1.184CysAla: 1.184 ± 0.01	0.579CysCys: 0.579 ± 0.007	1.015CysAsp: 1.015 ± 0.01	1.256CysGlu: 1.256 ± 0.011	0.78CysPhe: 0.78 ± 0.007	1.395CysGly: 1.395 ± 0.013	0.62CysHis: 0.62 ± 0.006	0.975CysIle: 0.975 ± 0.008	1.136CysLys: 1.136 ± 0.009	2.032CysLeu: 2.032 ± 0.014	0.391CysMet: 0.391 ± 0.004	0.784CysAsn: 0.784 ± 0.006	1.265CysPro: 1.265 ± 0.012	1.053CysGln: 1.053 ± 0.01	1.225CysArg: 1.225 ± 0.011	1.945CysSer: 1.945 ± 0.013	1.077CysThr: 1.077 ± 0.009	1.198CysVal: 1.198 ± 0.01	0.252CysTrp: 0.252 ± 0.004	0.564CysTyr: 0.564 ± 0.006	0.001CysXaa: 0.001 ± 0.0
Asp	2.974AspAla: 2.974 ± 0.014	1.038AspCys: 1.038 ± 0.009	2.766AspAsp: 2.766 ± 0.016	3.698AspGlu: 3.698 ± 0.018	2.059AspPhe: 2.059 ± 0.012	3.375AspGly: 3.375 ± 0.019	1.137AspHis: 1.137 ± 0.008	2.718AspIle: 2.718 ± 0.018	2.74AspLys: 2.74 ± 0.014	4.961AspLeu: 4.961 ± 0.02	1.153AspMet: 1.153 ± 0.008	1.821AspAsn: 1.821 ± 0.012	2.803AspPro: 2.803 ± 0.014	1.872AspGln: 1.872 ± 0.01	2.503AspArg: 2.503 ± 0.015	4.473AspSer: 4.473 ± 0.02	2.72AspThr: 2.72 ± 0.013	3.222AspVal: 3.222 ± 0.03	0.595AspTrp: 0.595 ± 0.007	1.506AspTyr: 1.506 ± 0.011	0.001AspXaa: 0.001 ± 0.0
Glu	5.124GluAla: 5.124 ± 0.027	1.243GluCys: 1.243 ± 0.011	4.598GluAsp: 4.598 ± 0.019	8.828GluGlu: 8.828 ± 0.044	2.022GluPhe: 2.022 ± 0.01	4.259GluGly: 4.259 ± 0.023	1.614GluHis: 1.614 ± 0.011	3.383GluIle: 3.383 ± 0.018	5.811GluLys: 5.811 ± 0.037	6.864GluLeu: 6.864 ± 0.038	1.886GluMet: 1.886 ± 0.012	3.357GluAsn: 3.357 ± 0.016	3.164GluPro: 3.164 ± 0.02	3.65GluGln: 3.65 ± 0.025	4.348GluArg: 4.348 ± 0.024	4.847GluSer: 4.847 ± 0.022	3.629GluThr: 3.629 ± 0.017	4.317GluVal: 4.317 ± 0.02	0.697GluTrp: 0.697 ± 0.006	1.679GluTyr: 1.679 ± 0.012	0.002GluXaa: 0.002 ± 0.0
Phe	1.947PheAla: 1.947 ± 0.012	0.835PheCys: 0.835 ± 0.009	1.619PheAsp: 1.619 ± 0.01	1.953PheGlu: 1.953 ± 0.01	1.426PhePhe: 1.426 ± 0.011	2.07PheGly: 2.07 ± 0.013	0.975PheHis: 0.975 ± 0.008	1.736PheIle: 1.736 ± 0.012	1.729PheLys: 1.729 ± 0.015	3.638PheLeu: 3.638 ± 0.023	0.719PheMet: 0.719 ± 0.007	1.294PheAsn: 1.294 ± 0.008	1.9PhePro: 1.9 ± 0.013	1.725PheGln: 1.725 ± 0.01	1.783PheArg: 1.783 ± 0.012	3.161PheSer: 3.161 ± 0.018	1.897PheThr: 1.897 ± 0.01	2.041PheVal: 2.041 ± 0.011	0.44PheTrp: 0.44 ± 0.005	1.084PheTyr: 1.084 ± 0.007	0.001PheXaa: 0.001 ± 0.0
Gly	4.333GlyAla: 4.333 ± 0.023	1.232GlyCys: 1.232 ± 0.012	3.178GlyAsp: 3.178 ± 0.016	3.956GlyGlu: 3.956 ± 0.022	2.233GlyPhe: 2.233 ± 0.015	4.779GlyGly: 4.779 ± 0.037	1.574GlyHis: 1.574 ± 0.011	2.736GlyIle: 2.736 ± 0.016	3.771GlyLys: 3.771 ± 0.021	5.135GlyLeu: 5.135 ± 0.022	1.363GlyMet: 1.363 ± 0.01	2.466GlyAsn: 2.466 ± 0.014	3.508GlyPro: 3.508 ± 0.047	2.696GlyGln: 2.696 ± 0.015	3.671GlyArg: 3.671 ± 0.018	5.951GlySer: 5.951 ± 0.027	3.722GlyThr: 3.722 ± 0.019	3.403GlyVal: 3.403 ± 0.018	0.75GlyTrp: 0.75 ± 0.008	1.709GlyTyr: 1.709 ± 0.015	0.002GlyXaa: 0.002 ± 0.0
His	1.291HisAla: 1.291 ± 0.01	0.69HisCys: 0.69 ± 0.007	0.921HisAsp: 0.921 ± 0.007	1.342HisGlu: 1.342 ± 0.01	0.994HisPhe: 0.994 ± 0.008	1.512HisGly: 1.512 ± 0.01	0.905HisHis: 0.905 ± 0.009	1.243HisIle: 1.243 ± 0.01	1.318HisLys: 1.318 ± 0.008	2.676HisLeu: 2.676 ± 0.014	0.573HisMet: 0.573 ± 0.006	0.915HisAsn: 0.915 ± 0.007	1.582HisPro: 1.582 ± 0.012	1.246HisGln: 1.246 ± 0.008	1.535HisArg: 1.535 ± 0.009	2.337HisSer: 2.337 ± 0.012	1.29HisThr: 1.29 ± 0.01	1.486HisVal: 1.486 ± 0.01	0.315HisTrp: 0.315 ± 0.004	0.802HisTyr: 0.802 ± 0.007	0.001HisXaa: 0.001 ± 0.0
Ile	2.678IleAla: 2.678 ± 0.012	1.027IleCys: 1.027 ± 0.008	2.12IleAsp: 2.12 ± 0.012	2.703IleGlu: 2.703 ± 0.017	1.734IlePhe: 1.734 ± 0.013	2.131IleGly: 2.131 ± 0.013	1.231IleHis: 1.231 ± 0.009	2.286IleIle: 2.286 ± 0.014	2.763IleLys: 2.763 ± 0.017	4.307IleLeu: 4.307 ± 0.02	0.972IleMet: 0.972 ± 0.008	1.936IleAsn: 1.936 ± 0.012	2.725IlePro: 2.725 ± 0.015	2.359IleGln: 2.359 ± 0.013	2.365IleArg: 2.365 ± 0.01	3.802IleSer: 3.802 ± 0.017	2.567IleThr: 2.567 ± 0.015	2.518IleVal: 2.518 ± 0.014	0.472IleTrp: 0.472 ± 0.006	1.324IleTyr: 1.324 ± 0.009	0.001IleXaa: 0.001 ± 0.0
Lys	4.059LysAla: 4.059 ± 0.02	1.101LysCys: 1.101 ± 0.008	3.373LysAsp: 3.373 ± 0.018	5.669LysGlu: 5.669 ± 0.034	1.677LysPhe: 1.677 ± 0.015	3.4LysGly: 3.4 ± 0.035	1.484LysHis: 1.484 ± 0.01	2.863LysIle: 2.863 ± 0.015	5.023LysLys: 5.023 ± 0.033	5.429LysLeu: 5.429 ± 0.026	1.498LysMet: 1.498 ± 0.013	2.516LysAsn: 2.516 ± 0.014	3.13LysPro: 3.13 ± 0.02	2.993LysGln: 2.993 ± 0.018	3.475LysArg: 3.475 ± 0.019	4.328LysSer: 4.328 ± 0.02	3.213LysThr: 3.213 ± 0.015	3.594LysVal: 3.594 ± 0.022	0.6LysTrp: 0.6 ± 0.007	1.6LysTyr: 1.6 ± 0.014	0.002LysXaa: 0.002 ± 0.0
Leu	6.32LeuAla: 6.32 ± 0.024	2.099LeuCys: 2.099 ± 0.012	4.731LeuAsp: 4.731 ± 0.018	7.47LeuGlu: 7.47 ± 0.043	3.043LeuPhe: 3.043 ± 0.018	5.193LeuGly: 5.193 ± 0.02	2.672LeuHis: 2.672 ± 0.015	3.635LeuIle: 3.635 ± 0.016	6.133LeuLys: 6.133 ± 0.036	10.101LeuLeu: 10.101 ± 0.045	1.939LeuMet: 1.939 ± 0.012	3.62LeuAsn: 3.62 ± 0.018	5.758LeuPro: 5.758 ± 0.025	5.896LeuGln: 5.896 ± 0.036	5.652LeuArg: 5.652 ± 0.026	7.879LeuSer: 7.879 ± 0.026	4.72LeuThr: 4.72 ± 0.016	5.062LeuVal: 5.062 ± 0.018	1.031LeuTrp: 1.031 ± 0.008	2.415LeuTyr: 2.415 ± 0.014	0.002LeuXaa: 0.002 ± 0.0
Met	1.804MetAla: 1.804 ± 0.01	0.383MetCys: 0.383 ± 0.005	1.308MetAsp: 1.308 ± 0.009	2.03MetGlu: 2.03 ± 0.012	0.73MetPhe: 0.73 ± 0.007	1.235MetGly: 1.235 ± 0.01	0.485MetHis: 0.485 ± 0.006	0.835MetIle: 0.835 ± 0.007	1.548MetLys: 1.548 ± 0.009	1.928MetLeu: 1.928 ± 0.01	0.573MetMet: 0.573 ± 0.006	0.927MetAsn: 0.927 ± 0.008	1.134MetPro: 1.134 ± 0.019	1.029MetGln: 1.029 ± 0.008	1.048MetArg: 1.048 ± 0.007	1.626MetSer: 1.626 ± 0.01	1.086MetThr: 1.086 ± 0.008	1.315MetVal: 1.315 ± 0.009	0.239MetTrp: 0.239 ± 0.003	0.554MetTyr: 0.554 ± 0.005	0.0MetXaa: 0.0 ± 0.0
Asn	2.253AsnAla: 2.253 ± 0.013	0.826AsnCys: 0.826 ± 0.007	1.635AsnAsp: 1.635 ± 0.013	2.422AsnGlu: 2.422 ± 0.014	1.414AsnPhe: 1.414 ± 0.009	2.636AsnGly: 2.636 ± 0.017	0.927AsnHis: 0.927 ± 0.007	2.208AsnIle: 2.208 ± 0.013	2.373AsnLys: 2.373 ± 0.013	3.758AsnLeu: 3.758 ± 0.018	0.943AsnMet: 0.943 ± 0.008	1.686AsnAsn: 1.686 ± 0.012	2.156AsnPro: 2.156 ± 0.013	1.748AsnGln: 1.748 ± 0.01	1.901AsnArg: 1.901 ± 0.011	3.436AsnSer: 3.436 ± 0.016	2.125AsnThr: 2.125 ± 0.014	2.298AsnVal: 2.298 ± 0.012	0.43AsnTrp: 0.43 ± 0.005	1.119AsnTyr: 1.119 ± 0.008	0.002AsnXaa: 0.002 ± 0.0
Pro	5.028ProAla: 5.028 ± 0.034	1.094ProCys: 1.094 ± 0.011	2.759ProAsp: 2.759 ± 0.018	4.357ProGlu: 4.357 ± 0.029	1.775ProPhe: 1.775 ± 0.011	4.824ProGly: 4.824 ± 0.051	1.378ProHis: 1.378 ± 0.01	1.83ProIle: 1.83 ± 0.011	2.92ProLys: 2.92 ± 0.039	4.974ProLeu: 4.974 ± 0.022	0.973ProMet: 0.973 ± 0.008	1.842ProAsn: 1.842 ± 0.012	5.945ProPro: 5.945 ± 0.054	2.709ProGln: 2.709 ± 0.019	3.154ProArg: 3.154 ± 0.021	5.686ProSer: 5.686 ± 0.029	2.962ProThr: 2.962 ± 0.02	3.934ProVal: 3.934 ± 0.018	0.622ProTrp: 0.622 ± 0.009	1.391ProTyr: 1.391 ± 0.01	0.002ProXaa: 0.002 ± 0.0
Gln	3.384GlnAla: 3.384 ± 0.018	0.929GlnCys: 0.929 ± 0.009	2.361GlnAsp: 2.361 ± 0.013	4.118GlnGlu: 4.118 ± 0.029	1.401GlnPhe: 1.401 ± 0.009	2.735GlnGly: 2.735 ± 0.016	1.395GlnHis: 1.395 ± 0.011	2.09GlnIle: 2.09 ± 0.013	3.192GlnLys: 3.192 ± 0.02	4.816GlnLeu: 4.816 ± 0.027	1.148GlnMet: 1.148 ± 0.009	2.01GlnAsn: 2.01 ± 0.012	2.861GlnPro: 2.861 ± 0.023	3.523GlnGln: 3.523 ± 0.035	2.954GlnArg: 2.954 ± 0.015	3.539GlnSer: 3.539 ± 0.016	2.432GlnThr: 2.432 ± 0.013	2.761GlnVal: 2.761 ± 0.013	0.54GlnTrp: 0.54 ± 0.007	1.206GlnTyr: 1.206 ± 0.009	0.001GlnXaa: 0.001 ± 0.0
Arg	3.796ArgAla: 3.796 ± 0.019	1.149ArgCys: 1.149 ± 0.011	2.872ArgAsp: 2.872 ± 0.018	4.199ArgGlu: 4.199 ± 0.022	1.751ArgPhe: 1.751 ± 0.01	3.482ArgGly: 3.482 ± 0.022	1.477ArgHis: 1.477 ± 0.009	2.411ArgIle: 2.411 ± 0.012	3.745ArgLys: 3.745 ± 0.019	5.077ArgLeu: 5.077 ± 0.021	1.195ArgMet: 1.195 ± 0.008	2.177ArgAsn: 2.177 ± 0.013	2.921ArgPro: 2.921 ± 0.019	2.731ArgGln: 2.731 ± 0.016	4.481ArgArg: 4.481 ± 0.027	4.55ArgSer: 4.55 ± 0.027	2.819ArgThr: 2.819 ± 0.013	3.005ArgVal: 3.005 ± 0.015	0.644ArgTrp: 0.644 ± 0.006	1.441ArgTyr: 1.441 ± 0.009	0.002ArgXaa: 0.002 ± 0.0
Ser	5.722SerAla: 5.722 ± 0.024	1.797SerCys: 1.797 ± 0.013	4.199SerAsp: 4.199 ± 0.021	5.55SerGlu: 5.55 ± 0.025	2.895SerPhe: 2.895 ± 0.014	5.475SerGly: 5.475 ± 0.021	2.066SerHis: 2.066 ± 0.01	3.346SerIle: 3.346 ± 0.016	4.461SerLys: 4.461 ± 0.018	8.109SerLeu: 8.109 ± 0.028	1.69SerMet: 1.69 ± 0.01	2.927SerAsn: 2.927 ± 0.016	6.248SerPro: 6.248 ± 0.035	4.053SerGln: 4.053 ± 0.021	4.626SerArg: 4.626 ± 0.022	10.186SerSer: 10.186 ± 0.052	4.846SerThr: 4.846 ± 0.023	5.111SerVal: 5.111 ± 0.02	0.975SerTrp: 0.975 ± 0.008	2.056SerTyr: 2.056 ± 0.013	0.002SerXaa: 0.002 ± 0.0
Thr	4.06ThrAla: 4.06 ± 0.02	1.224ThrCys: 1.224 ± 0.012	2.716ThrAsp: 2.716 ± 0.015	3.881ThrGlu: 3.881 ± 0.019	1.936ThrPhe: 1.936 ± 0.012	3.481ThrGly: 3.481 ± 0.018	1.162ThrHis: 1.162 ± 0.008	2.311ThrIle: 2.311 ± 0.013	2.755ThrLys: 2.755 ± 0.014	5.015ThrLeu: 5.015 ± 0.018	1.092ThrMet: 1.092 ± 0.007	1.831ThrAsn: 1.831 ± 0.01	3.631ThrPro: 3.631 ± 0.026	2.231ThrGln: 2.231 ± 0.012	2.423ThrArg: 2.423 ± 0.013	4.833ThrSer: 4.833 ± 0.024	3.105ThrThr: 3.105 ± 0.026	3.888ThrVal: 3.888 ± 0.019	0.648ThrTrp: 0.648 ± 0.008	1.352ThrTyr: 1.352 ± 0.01	0.002ThrXaa: 0.002 ± 0.0
Val	4.113ValAla: 4.113 ± 0.018	1.371ValCys: 1.371 ± 0.012	2.968ValAsp: 2.968 ± 0.026	4.013ValGlu: 4.013 ± 0.018	2.242ValPhe: 2.242 ± 0.014	3.159ValGly: 3.159 ± 0.016	1.485ValHis: 1.485 ± 0.01	2.815ValIle: 2.815 ± 0.016	3.622ValLys: 3.622 ± 0.021	5.998ValLeu: 5.998 ± 0.02	1.297ValMet: 1.297 ± 0.008	2.38ValAsn: 2.38 ± 0.012	3.803ValPro: 3.803 ± 0.023	2.875ValGln: 2.875 ± 0.015	2.997ValArg: 2.997 ± 0.013	5.04ValSer: 5.04 ± 0.021	3.821ValThr: 3.821 ± 0.02	3.906ValVal: 3.906 ± 0.019	0.635ValTrp: 0.635 ± 0.006	1.55ValTyr: 1.55 ± 0.009	0.001ValXaa: 0.001 ± 0.0
Trp	0.674TrpAla: 0.674 ± 0.006	0.224TrpCys: 0.224 ± 0.004	0.627TrpAsp: 0.627 ± 0.007	0.827TrpGlu: 0.827 ± 0.01	0.397TrpPhe: 0.397 ± 0.005	0.625TrpGly: 0.625 ± 0.009	0.294TrpHis: 0.294 ± 0.004	0.552TrpIle: 0.552 ± 0.007	0.772TrpLys: 0.772 ± 0.007	1.164TrpLeu: 1.164 ± 0.011	0.296TrpMet: 0.296 ± 0.003	0.531TrpAsn: 0.531 ± 0.007	0.447TrpPro: 0.447 ± 0.005	0.531TrpGln: 0.531 ± 0.006	0.666TrpArg: 0.666 ± 0.007	0.849TrpSer: 0.849 ± 0.009	0.6TrpThr: 0.6 ± 0.007	0.591TrpVal: 0.591 ± 0.007	0.165TrpTrp: 0.165 ± 0.004	0.297TrpTyr: 0.297 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.35TyrAla: 1.35 ± 0.009	0.644TyrCys: 0.644 ± 0.007	1.29TyrAsp: 1.29 ± 0.01	1.689TyrGlu: 1.689 ± 0.012	1.115TyrPhe: 1.115 ± 0.008	1.605TyrGly: 1.605 ± 0.01	0.71TyrHis: 0.71 ± 0.007	1.359TyrIle: 1.359 ± 0.01	1.529TyrLys: 1.529 ± 0.019	2.508TyrLeu: 2.508 ± 0.014	0.586TyrMet: 0.586 ± 0.005	1.095TyrAsn: 1.095 ± 0.007	1.205TyrPro: 1.205 ± 0.01	1.218TyrGln: 1.218 ± 0.009	1.579TyrArg: 1.579 ± 0.012	2.274TyrSer: 2.274 ± 0.014	1.453TyrThr: 1.453 ± 0.011	1.483TyrVal: 1.483 ± 0.009	0.352TyrTrp: 0.352 ± 0.006	0.895TyrTyr: 0.895 ± 0.008	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.003XaaGly: 0.003 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.002XaaGln: 0.002 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.002XaaSer: 0.002 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.001XaaXaa: 0.001 ± 0.0

Statistics based on 29436 proteins (21854273 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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