Amino acid dipepetide frequency for Oligella urethralis DNF00040

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.065AlaAla: 11.065 ± 0.199
0.973AlaCys: 0.973 ± 0.041
5.13AlaAsp: 5.13 ± 0.096
6.876AlaGlu: 6.876 ± 0.127
3.586AlaPhe: 3.586 ± 0.076
6.707AlaGly: 6.707 ± 0.124
2.073AlaHis: 2.073 ± 0.057
6.226AlaIle: 6.226 ± 0.106
5.202AlaLys: 5.202 ± 0.095
11.391AlaLeu: 11.391 ± 0.178
2.873AlaMet: 2.873 ± 0.069
3.279AlaAsn: 3.279 ± 0.076
3.626AlaPro: 3.626 ± 0.09
4.936AlaGln: 4.936 ± 0.117
5.025AlaArg: 5.025 ± 0.105
5.336AlaSer: 5.336 ± 0.103
4.935AlaThr: 4.935 ± 0.106
6.604AlaVal: 6.604 ± 0.109
1.256AlaTrp: 1.256 ± 0.043
2.688AlaTyr: 2.688 ± 0.076
0.0AlaXaa: 0.0 ± 0.0
Cys
0.782CysAla: 0.782 ± 0.036
0.116CysCys: 0.116 ± 0.014
0.43CysAsp: 0.43 ± 0.026
0.499CysGlu: 0.499 ± 0.028
0.404CysPhe: 0.404 ± 0.024
0.775CysGly: 0.775 ± 0.034
0.298CysHis: 0.298 ± 0.022
0.494CysIle: 0.494 ± 0.031
0.273CysLys: 0.273 ± 0.018
0.941CysLeu: 0.941 ± 0.04
0.177CysMet: 0.177 ± 0.016
0.247CysAsn: 0.247 ± 0.019
0.471CysPro: 0.471 ± 0.03
0.345CysGln: 0.345 ± 0.024
0.446CysArg: 0.446 ± 0.028
0.537CysSer: 0.537 ± 0.027
0.393CysThr: 0.393 ± 0.025
0.635CysVal: 0.635 ± 0.034
0.125CysTrp: 0.125 ± 0.014
0.301CysTyr: 0.301 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
4.789AspAla: 4.789 ± 0.099
0.433AspCys: 0.433 ± 0.026
2.748AspAsp: 2.748 ± 0.067
4.144AspGlu: 4.144 ± 0.095
2.514AspPhe: 2.514 ± 0.062
3.652AspGly: 3.652 ± 0.079
1.04AspHis: 1.04 ± 0.046
3.495AspIle: 3.495 ± 0.07
2.648AspLys: 2.648 ± 0.062
5.46AspLeu: 5.46 ± 0.098
1.316AspMet: 1.316 ± 0.041
1.959AspAsn: 1.959 ± 0.054
2.322AspPro: 2.322 ± 0.067
1.7AspGln: 1.7 ± 0.055
2.608AspArg: 2.608 ± 0.061
2.962AspSer: 2.962 ± 0.074
2.312AspThr: 2.312 ± 0.053
3.581AspVal: 3.581 ± 0.08
0.806AspTrp: 0.806 ± 0.035
2.11AspTyr: 2.11 ± 0.06
0.0AspXaa: 0.0 ± 0.0
Glu
6.728GluAla: 6.728 ± 0.125
0.384GluCys: 0.384 ± 0.028
3.037GluAsp: 3.037 ± 0.066
4.137GluGlu: 4.137 ± 0.094
2.254GluPhe: 2.254 ± 0.069
4.007GluGly: 4.007 ± 0.095
1.682GluHis: 1.682 ± 0.052
3.946GluIle: 3.946 ± 0.084
2.866GluLys: 2.866 ± 0.07
6.931GluLeu: 6.931 ± 0.113
1.515GluMet: 1.515 ± 0.047
2.072GluAsn: 2.072 ± 0.057
2.318GluPro: 2.318 ± 0.072
4.028GluGln: 4.028 ± 0.09
4.289GluArg: 4.289 ± 0.085
3.357GluSer: 3.357 ± 0.079
2.76GluThr: 2.76 ± 0.072
4.801GluVal: 4.801 ± 0.091
0.708GluTrp: 0.708 ± 0.034
1.592GluTyr: 1.592 ± 0.056
0.0GluXaa: 0.0 ± 0.0
Phe
3.743PheAla: 3.743 ± 0.074
0.429PheCys: 0.429 ± 0.025
2.636PheAsp: 2.636 ± 0.063
2.624PheGlu: 2.624 ± 0.066
1.911PhePhe: 1.911 ± 0.057
3.088PheGly: 3.088 ± 0.069
0.689PheHis: 0.689 ± 0.032
2.678PheIle: 2.678 ± 0.064
2.156PheLys: 2.156 ± 0.065
3.728PheLeu: 3.728 ± 0.086
0.989PheMet: 0.989 ± 0.034
1.973PheAsn: 1.973 ± 0.06
1.444PhePro: 1.444 ± 0.051
1.096PheGln: 1.096 ± 0.041
1.688PheArg: 1.688 ± 0.05
2.891PheSer: 2.891 ± 0.063
1.956PheThr: 1.956 ± 0.053
2.779PheVal: 2.779 ± 0.071
0.509PheTrp: 0.509 ± 0.034
1.309PheTyr: 1.309 ± 0.046
0.0PheXaa: 0.0 ± 0.0
Gly
6.289GlyAla: 6.289 ± 0.103
0.647GlyCys: 0.647 ± 0.034
3.437GlyAsp: 3.437 ± 0.081
4.055GlyGlu: 4.055 ± 0.084
3.202GlyPhe: 3.202 ± 0.07
5.089GlyGly: 5.089 ± 0.11
1.474GlyHis: 1.474 ± 0.052
4.612GlyIle: 4.612 ± 0.097
3.351GlyLys: 3.351 ± 0.083
7.556GlyLeu: 7.556 ± 0.113
1.989GlyMet: 1.989 ± 0.054
2.081GlyAsn: 2.081 ± 0.061
2.078GlyPro: 2.078 ± 0.055
2.957GlyGln: 2.957 ± 0.078
3.882GlyArg: 3.882 ± 0.085
4.054GlySer: 4.054 ± 0.086
3.738GlyThr: 3.738 ± 0.073
5.503GlyVal: 5.503 ± 0.123
0.867GlyTrp: 0.867 ± 0.04
2.239GlyTyr: 2.239 ± 0.061
0.0GlyXaa: 0.0 ± 0.0
His
1.982HisAla: 1.982 ± 0.058
0.305HisCys: 0.305 ± 0.021
1.207HisAsp: 1.207 ± 0.05
1.252HisGlu: 1.252 ± 0.045
1.011HisPhe: 1.011 ± 0.048
1.646HisGly: 1.646 ± 0.055
0.695HisHis: 0.695 ± 0.037
1.39HisIle: 1.39 ± 0.044
0.862HisLys: 0.862 ± 0.037
2.323HisLeu: 2.323 ± 0.062
0.491HisMet: 0.491 ± 0.026
0.766HisAsn: 0.766 ± 0.037
1.272HisPro: 1.272 ± 0.044
1.255HisGln: 1.255 ± 0.042
1.268HisArg: 1.268 ± 0.042
1.346HisSer: 1.346 ± 0.045
1.003HisThr: 1.003 ± 0.041
1.266HisVal: 1.266 ± 0.046
0.332HisTrp: 0.332 ± 0.026
0.904HisTyr: 0.904 ± 0.036
0.0HisXaa: 0.0 ± 0.0
Ile
6.382IleAla: 6.382 ± 0.112
0.614IleCys: 0.614 ± 0.033
3.887IleAsp: 3.887 ± 0.083
4.337IleGlu: 4.337 ± 0.087
2.345IlePhe: 2.345 ± 0.068
4.637IleGly: 4.637 ± 0.093
1.259IleHis: 1.259 ± 0.043
3.606IleIle: 3.606 ± 0.084
3.149IleLys: 3.149 ± 0.066
5.487IleLeu: 5.487 ± 0.109
1.304IleMet: 1.304 ± 0.044
2.684IleAsn: 2.684 ± 0.058
2.719IlePro: 2.719 ± 0.063
2.337IleGln: 2.337 ± 0.057
3.273IleArg: 3.273 ± 0.066
4.052IleSer: 4.052 ± 0.075
3.16IleThr: 3.16 ± 0.07
4.253IleVal: 4.253 ± 0.087
0.634IleTrp: 0.634 ± 0.031
1.82IleTyr: 1.82 ± 0.047
0.0IleXaa: 0.0 ± 0.0
Lys
5.3LysAla: 5.3 ± 0.099
0.185LysCys: 0.185 ± 0.017
2.46LysAsp: 2.46 ± 0.068
3.119LysGlu: 3.119 ± 0.076
1.343LysPhe: 1.343 ± 0.045
2.971LysGly: 2.971 ± 0.076
1.179LysHis: 1.179 ± 0.041
2.606LysIle: 2.606 ± 0.073
2.716LysLys: 2.716 ± 0.068
4.472LysLeu: 4.472 ± 0.084
1.184LysMet: 1.184 ± 0.044
1.977LysAsn: 1.977 ± 0.058
2.187LysPro: 2.187 ± 0.06
2.466LysGln: 2.466 ± 0.061
2.864LysArg: 2.864 ± 0.069
2.831LysSer: 2.831 ± 0.07
2.539LysThr: 2.539 ± 0.055
3.161LysVal: 3.161 ± 0.066
0.445LysTrp: 0.445 ± 0.026
1.211LysTyr: 1.211 ± 0.046
0.0LysXaa: 0.0 ± 0.0
Leu
11.469LeuAla: 11.469 ± 0.16
1.047LeuCys: 1.047 ± 0.039
5.743LeuAsp: 5.743 ± 0.099
6.028LeuGlu: 6.028 ± 0.103
4.076LeuPhe: 4.076 ± 0.093
7.197LeuGly: 7.197 ± 0.115
2.15LeuHis: 2.15 ± 0.059
6.68LeuIle: 6.68 ± 0.12
5.365LeuLys: 5.365 ± 0.108
11.242LeuLeu: 11.242 ± 0.196
2.718LeuMet: 2.718 ± 0.065
4.506LeuAsn: 4.506 ± 0.085
4.813LeuPro: 4.813 ± 0.09
4.334LeuGln: 4.334 ± 0.093
5.746LeuArg: 5.746 ± 0.105
8.256LeuSer: 8.256 ± 0.132
4.97LeuThr: 4.97 ± 0.083
6.899LeuVal: 6.899 ± 0.11
1.112LeuTrp: 1.112 ± 0.046
2.736LeuTyr: 2.736 ± 0.075
0.0LeuXaa: 0.0 ± 0.0
Met
2.601MetAla: 2.601 ± 0.069
0.183MetCys: 0.183 ± 0.017
1.213MetAsp: 1.213 ± 0.038
1.137MetGlu: 1.137 ± 0.04
0.837MetPhe: 0.837 ± 0.038
1.745MetGly: 1.745 ± 0.053
0.55MetHis: 0.55 ± 0.028
1.45MetIle: 1.45 ± 0.045
1.178MetLys: 1.178 ± 0.039
2.678MetLeu: 2.678 ± 0.066
0.731MetMet: 0.731 ± 0.039
1.048MetAsn: 1.048 ± 0.038
1.275MetPro: 1.275 ± 0.047
1.278MetGln: 1.278 ± 0.046
1.489MetArg: 1.489 ± 0.045
2.033MetSer: 2.033 ± 0.053
1.441MetThr: 1.441 ± 0.056
1.754MetVal: 1.754 ± 0.049
0.199MetTrp: 0.199 ± 0.018
0.518MetTyr: 0.518 ± 0.027
0.0MetXaa: 0.0 ± 0.0
Asn
3.331AsnAla: 3.331 ± 0.063
0.323AsnCys: 0.323 ± 0.021
1.828AsnAsp: 1.828 ± 0.053
2.07AsnGlu: 2.07 ± 0.062
1.405AsnPhe: 1.405 ± 0.046
2.408AsnGly: 2.408 ± 0.065
0.931AsnHis: 0.931 ± 0.038
2.306AsnIle: 2.306 ± 0.057
1.847AsnLys: 1.847 ± 0.059
3.764AsnLeu: 3.764 ± 0.09
0.919AsnMet: 0.919 ± 0.041
1.48AsnAsn: 1.48 ± 0.055
2.193AsnPro: 2.193 ± 0.061
2.005AsnGln: 2.005 ± 0.058
2.148AsnArg: 2.148 ± 0.054
2.088AsnSer: 2.088 ± 0.072
2.004AsnThr: 2.004 ± 0.06
2.159AsnVal: 2.159 ± 0.066
0.464AsnTrp: 0.464 ± 0.022
1.262AsnTyr: 1.262 ± 0.043
0.0AsnXaa: 0.0 ± 0.0
Pro
3.987ProAla: 3.987 ± 0.094
0.304ProCys: 0.304 ± 0.021
2.392ProAsp: 2.392 ± 0.068
3.574ProGlu: 3.574 ± 0.088
1.69ProPhe: 1.69 ± 0.057
2.802ProGly: 2.802 ± 0.078
0.939ProHis: 0.939 ± 0.036
2.456ProIle: 2.456 ± 0.058
2.05ProLys: 2.05 ± 0.057
4.417ProLeu: 4.417 ± 0.086
1.031ProMet: 1.031 ± 0.041
1.602ProAsn: 1.602 ± 0.053
1.343ProPro: 1.343 ± 0.049
1.881ProGln: 1.881 ± 0.056
1.71ProArg: 1.71 ± 0.054
2.594ProSer: 2.594 ± 0.067
2.13ProThr: 2.13 ± 0.056
3.186ProVal: 3.186 ± 0.065
0.599ProTrp: 0.599 ± 0.032
1.378ProTyr: 1.378 ± 0.043
0.0ProXaa: 0.0 ± 0.0
Gln
5.422GlnAla: 5.422 ± 0.122
0.317GlnCys: 0.317 ± 0.022
2.072GlnAsp: 2.072 ± 0.057
2.592GlnGlu: 2.592 ± 0.07
1.694GlnPhe: 1.694 ± 0.054
3.046GlnGly: 3.046 ± 0.087
1.253GlnHis: 1.253 ± 0.041
2.576GlnIle: 2.576 ± 0.062
1.919GlnLys: 1.919 ± 0.054
5.271GlnLeu: 5.271 ± 0.116
1.012GlnMet: 1.012 ± 0.038
1.477GlnAsn: 1.477 ± 0.05
1.674GlnPro: 1.674 ± 0.054
3.144GlnGln: 3.144 ± 0.098
3.048GlnArg: 3.048 ± 0.072
2.87GlnSer: 2.87 ± 0.083
1.995GlnThr: 1.995 ± 0.066
2.991GlnVal: 2.991 ± 0.066
0.742GlnTrp: 0.742 ± 0.033
1.223GlnTyr: 1.223 ± 0.045
0.0GlnXaa: 0.0 ± 0.0
Arg
4.615ArgAla: 4.615 ± 0.079
0.426ArgCys: 0.426 ± 0.022
2.699ArgAsp: 2.699 ± 0.066
3.561ArgGlu: 3.561 ± 0.09
2.614ArgPhe: 2.614 ± 0.061
3.234ArgGly: 3.234 ± 0.071
1.378ArgHis: 1.378 ± 0.041
3.684ArgIle: 3.684 ± 0.072
2.188ArgLys: 2.188 ± 0.063
6.379ArgLeu: 6.379 ± 0.111
1.431ArgMet: 1.431 ± 0.046
1.957ArgAsn: 1.957 ± 0.051
2.201ArgPro: 2.201 ± 0.063
2.882ArgGln: 2.882 ± 0.078
3.405ArgArg: 3.405 ± 0.093
3.094ArgSer: 3.094 ± 0.076
2.175ArgThr: 2.175 ± 0.059
3.676ArgVal: 3.676 ± 0.088
0.778ArgTrp: 0.778 ± 0.034
2.091ArgTyr: 2.091 ± 0.061
0.0ArgXaa: 0.0 ± 0.0
Ser
5.586SerAla: 5.586 ± 0.124
0.512SerCys: 0.512 ± 0.025
3.109SerAsp: 3.109 ± 0.066
3.59SerGlu: 3.59 ± 0.082
2.847SerPhe: 2.847 ± 0.07
4.816SerGly: 4.816 ± 0.084
1.406SerHis: 1.406 ± 0.046
3.684SerIle: 3.684 ± 0.085
2.832SerLys: 2.832 ± 0.067
7.103SerLeu: 7.103 ± 0.118
1.64SerMet: 1.64 ± 0.045
2.322SerAsn: 2.322 ± 0.06
2.456SerPro: 2.456 ± 0.064
2.53SerGln: 2.53 ± 0.065
3.08SerArg: 3.08 ± 0.057
4.1SerSer: 4.1 ± 0.094
3.28SerThr: 3.28 ± 0.078
3.993SerVal: 3.993 ± 0.089
0.771SerTrp: 0.771 ± 0.035
2.098SerTyr: 2.098 ± 0.057
0.0SerXaa: 0.0 ± 0.0
Thr
4.894ThrAla: 4.894 ± 0.087
0.371ThrCys: 0.371 ± 0.024
2.398ThrAsp: 2.398 ± 0.066
3.043ThrGlu: 3.043 ± 0.079
1.716ThrPhe: 1.716 ± 0.053
3.62ThrGly: 3.62 ± 0.087
1.138ThrHis: 1.138 ± 0.045
3.165ThrIle: 3.165 ± 0.076
2.089ThrLys: 2.089 ± 0.066
5.48ThrLeu: 5.48 ± 0.085
1.143ThrMet: 1.143 ± 0.041
1.544ThrAsn: 1.544 ± 0.055
2.774ThrPro: 2.774 ± 0.064
2.133ThrGln: 2.133 ± 0.063
2.363ThrArg: 2.363 ± 0.064
2.622ThrSer: 2.622 ± 0.071
2.763ThrThr: 2.763 ± 0.071
3.933ThrVal: 3.933 ± 0.071
0.561ThrTrp: 0.561 ± 0.03
1.137ThrTyr: 1.137 ± 0.045
0.0ThrXaa: 0.0 ± 0.0
Val
7.191ValAla: 7.191 ± 0.122
0.672ValCys: 0.672 ± 0.035
3.885ValAsp: 3.885 ± 0.079
4.275ValGlu: 4.275 ± 0.072
2.975ValPhe: 2.975 ± 0.071
4.673ValGly: 4.673 ± 0.084
1.329ValHis: 1.329 ± 0.042
4.622ValIle: 4.622 ± 0.082
2.898ValLys: 2.898 ± 0.078
7.411ValLeu: 7.411 ± 0.118
1.94ValMet: 1.94 ± 0.058
2.617ValAsn: 2.617 ± 0.061
2.985ValPro: 2.985 ± 0.06
2.579ValGln: 2.579 ± 0.068
3.445ValArg: 3.445 ± 0.078
4.299ValSer: 4.299 ± 0.081
3.495ValThr: 3.495 ± 0.071
5.358ValVal: 5.358 ± 0.108
0.75ValTrp: 0.75 ± 0.029
1.931ValTyr: 1.931 ± 0.049
0.0ValXaa: 0.0 ± 0.0
Trp
0.983TrpAla: 0.983 ± 0.043
0.112TrpCys: 0.112 ± 0.012
0.603TrpAsp: 0.603 ± 0.031
0.58TrpGlu: 0.58 ± 0.025
0.529TrpPhe: 0.529 ± 0.029
0.749TrpGly: 0.749 ± 0.039
0.356TrpHis: 0.356 ± 0.025
0.734TrpIle: 0.734 ± 0.035
0.345TrpLys: 0.345 ± 0.022
1.78TrpLeu: 1.78 ± 0.057
0.329TrpMet: 0.329 ± 0.022
0.416TrpAsn: 0.416 ± 0.032
0.491TrpPro: 0.491 ± 0.03
0.846TrpGln: 0.846 ± 0.039
0.826TrpArg: 0.826 ± 0.038
0.717TrpSer: 0.717 ± 0.033
0.49TrpThr: 0.49 ± 0.029
0.84TrpVal: 0.84 ± 0.038
0.182TrpTrp: 0.182 ± 0.015
0.363TrpTyr: 0.363 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.649TyrAla: 2.649 ± 0.053
0.339TyrCys: 0.339 ± 0.022
1.685TyrAsp: 1.685 ± 0.053
1.918TyrGlu: 1.918 ± 0.063
1.364TyrPhe: 1.364 ± 0.046
2.241TyrGly: 2.241 ± 0.057
0.756TyrHis: 0.756 ± 0.035
1.527TyrIle: 1.527 ± 0.045
1.28TyrLys: 1.28 ± 0.049
3.273TyrLeu: 3.273 ± 0.065
0.605TyrMet: 0.605 ± 0.026
0.925TyrAsn: 0.925 ± 0.04
1.423TyrPro: 1.423 ± 0.049
1.605TyrGln: 1.605 ± 0.054
1.865TyrArg: 1.865 ± 0.051
1.716TyrSer: 1.716 ± 0.047
1.351TyrThr: 1.351 ± 0.041
1.959TyrVal: 1.959 ± 0.056
0.433TyrTrp: 0.433 ± 0.026
0.981TyrTyr: 0.981 ± 0.05
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2118 proteins (687764 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski