Amino acid dipepetide frequency for Trichinella nelsoni

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.55AlaAla: 5.55 ± 0.049	1.489AlaCys: 1.489 ± 0.015	3.58AlaAsp: 3.58 ± 0.026	4.446AlaGlu: 4.446 ± 0.029	2.776AlaPhe: 2.776 ± 0.02	3.316AlaGly: 3.316 ± 0.028	1.303AlaHis: 1.303 ± 0.013	3.406AlaIle: 3.406 ± 0.024	3.613AlaLys: 3.613 ± 0.024	6.19AlaLeu: 6.19 ± 0.037	1.594AlaMet: 1.594 ± 0.015	2.9AlaAsn: 2.9 ± 0.02	2.345AlaPro: 2.345 ± 0.021	2.28AlaGln: 2.28 ± 0.019	2.979AlaArg: 2.979 ± 0.021	5.258AlaSer: 5.258 ± 0.03	3.535AlaThr: 3.535 ± 0.025	5.072AlaVal: 5.072 ± 0.029	0.683AlaTrp: 0.683 ± 0.01	1.849AlaTyr: 1.849 ± 0.015	0.001AlaXaa: 0.001 ± 0.0
Cys	1.433CysAla: 1.433 ± 0.016	0.886CysCys: 0.886 ± 0.016	1.342CysAsp: 1.342 ± 0.019	1.456CysGlu: 1.456 ± 0.019	1.319CysPhe: 1.319 ± 0.015	1.439CysGly: 1.439 ± 0.016	0.696CysHis: 0.696 ± 0.011	1.545CysIle: 1.545 ± 0.02	1.451CysLys: 1.451 ± 0.018	2.549CysLeu: 2.549 ± 0.023	0.567CysMet: 0.567 ± 0.009	1.194CysAsn: 1.194 ± 0.014	1.218CysPro: 1.218 ± 0.025	1.099CysGln: 1.099 ± 0.014	1.623CysArg: 1.623 ± 0.016	2.434CysSer: 2.434 ± 0.023	1.368CysThr: 1.368 ± 0.015	1.505CysVal: 1.505 ± 0.02	0.341CysTrp: 0.341 ± 0.007	0.768CysTyr: 0.768 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	3.269AspAla: 3.269 ± 0.022	1.368AspCys: 1.368 ± 0.017	4.004AspAsp: 4.004 ± 0.037	4.301AspGlu: 4.301 ± 0.031	2.398AspPhe: 2.398 ± 0.019	3.144AspGly: 3.144 ± 0.035	1.233AspHis: 1.233 ± 0.011	2.78AspIle: 2.78 ± 0.02	2.57AspLys: 2.57 ± 0.02	4.695AspLeu: 4.695 ± 0.025	1.166AspMet: 1.166 ± 0.012	2.363AspAsn: 2.363 ± 0.019	2.053AspPro: 2.053 ± 0.02	2.052AspGln: 2.052 ± 0.017	2.756AspArg: 2.756 ± 0.021	4.193AspSer: 4.193 ± 0.025	2.163AspThr: 2.163 ± 0.017	3.712AspVal: 3.712 ± 0.022	0.686AspTrp: 0.686 ± 0.011	1.624AspTyr: 1.624 ± 0.014	0.0AspXaa: 0.0 ± 0.0
Glu	3.876GluAla: 3.876 ± 0.031	1.352GluCys: 1.352 ± 0.019	3.241GluAsp: 3.241 ± 0.025	5.52GluGlu: 5.52 ± 0.051	2.448GluPhe: 2.448 ± 0.019	2.285GluGly: 2.285 ± 0.023	1.402GluHis: 1.402 ± 0.015	3.993GluIle: 3.993 ± 0.029	5.012GluLys: 5.012 ± 0.036	5.771GluLeu: 5.771 ± 0.034	1.932GluMet: 1.932 ± 0.016	4.06GluAsn: 4.06 ± 0.027	2.163GluPro: 2.163 ± 0.017	3.052GluGln: 3.052 ± 0.024	3.564GluArg: 3.564 ± 0.027	4.494GluSer: 4.494 ± 0.028	3.285GluThr: 3.285 ± 0.023	3.514GluVal: 3.514 ± 0.027	0.676GluTrp: 0.676 ± 0.01	1.75GluTyr: 1.75 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.793PheAla: 2.793 ± 0.023	1.409PheCys: 1.409 ± 0.014	2.638PheAsp: 2.638 ± 0.019	2.649PheGlu: 2.649 ± 0.02	2.255PhePhe: 2.255 ± 0.019	2.645PheGly: 2.645 ± 0.021	1.296PheHis: 1.296 ± 0.012	2.585PheIle: 2.585 ± 0.022	2.222PheLys: 2.222 ± 0.017	4.406PheLeu: 4.406 ± 0.031	0.911PheMet: 0.911 ± 0.012	2.112PheAsn: 2.112 ± 0.017	2.012PhePro: 2.012 ± 0.016	1.953PheGln: 1.953 ± 0.017	2.351PheArg: 2.351 ± 0.023	3.934PheSer: 3.934 ± 0.022	2.438PheThr: 2.438 ± 0.018	3.105PheVal: 3.105 ± 0.023	0.614PheTrp: 0.614 ± 0.01	1.722PheTyr: 1.722 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	2.707GlyAla: 2.707 ± 0.027	1.265GlyCys: 1.265 ± 0.014	2.636GlyAsp: 2.636 ± 0.022	2.884GlyGlu: 2.884 ± 0.028	2.284GlyPhe: 2.284 ± 0.02	3.303GlyGly: 3.303 ± 0.037	1.275GlyHis: 1.275 ± 0.013	2.902GlyIle: 2.902 ± 0.021	3.332GlyLys: 3.332 ± 0.025	4.087GlyLeu: 4.087 ± 0.029	1.205GlyMet: 1.205 ± 0.015	2.491GlyAsn: 2.491 ± 0.022	1.805GlyPro: 1.805 ± 0.026	2.059GlyGln: 2.059 ± 0.021	3.251GlyArg: 3.251 ± 0.027	4.232GlySer: 4.232 ± 0.032	2.625GlyThr: 2.625 ± 0.021	3.042GlyVal: 3.042 ± 0.024	0.662GlyTrp: 0.662 ± 0.01	1.738GlyTyr: 1.738 ± 0.019	0.001GlyXaa: 0.001 ± 0.0
His	1.409HisAla: 1.409 ± 0.014	0.883HisCys: 0.883 ± 0.013	1.025HisAsp: 1.025 ± 0.011	1.22HisGlu: 1.22 ± 0.013	1.421HisPhe: 1.421 ± 0.016	1.317HisGly: 1.317 ± 0.015	0.945HisHis: 0.945 ± 0.018	1.282HisIle: 1.282 ± 0.013	0.992HisLys: 0.992 ± 0.012	2.728HisLeu: 2.728 ± 0.021	0.54HisMet: 0.54 ± 0.008	0.973HisAsn: 0.973 ± 0.013	1.237HisPro: 1.237 ± 0.013	1.106HisGln: 1.106 ± 0.014	1.549HisArg: 1.549 ± 0.015	2.005HisSer: 2.005 ± 0.018	1.07HisThr: 1.07 ± 0.01	1.586HisVal: 1.586 ± 0.013	0.363HisTrp: 0.363 ± 0.007	0.883HisTyr: 0.883 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	3.703IleAla: 3.703 ± 0.023	1.695IleCys: 1.695 ± 0.019	3.009IleAsp: 3.009 ± 0.02	3.274IleGlu: 3.274 ± 0.022	2.876IlePhe: 2.876 ± 0.026	2.882IleGly: 2.882 ± 0.023	1.341IleHis: 1.341 ± 0.014	3.136IleIle: 3.136 ± 0.024	2.827IleLys: 2.827 ± 0.021	5.323IleLeu: 5.323 ± 0.03	1.214IleMet: 1.214 ± 0.014	2.452IleAsn: 2.452 ± 0.02	2.602IlePro: 2.602 ± 0.021	2.194IleGln: 2.194 ± 0.019	3.115IleArg: 3.115 ± 0.019	4.727IleSer: 4.727 ± 0.027	2.814IleThr: 2.814 ± 0.02	3.677IleVal: 3.677 ± 0.024	0.686IleTrp: 0.686 ± 0.01	1.895IleTyr: 1.895 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	3.611LysAla: 3.611 ± 0.026	1.477LysCys: 1.477 ± 0.018	2.617LysAsp: 2.617 ± 0.023	3.935LysGlu: 3.935 ± 0.032	2.552LysPhe: 2.552 ± 0.017	2.258LysGly: 2.258 ± 0.024	1.475LysHis: 1.475 ± 0.016	3.561LysIle: 3.561 ± 0.023	4.601LysLys: 4.601 ± 0.044	6.169LysLeu: 6.169 ± 0.036	1.734LysMet: 1.734 ± 0.017	3.208LysAsn: 3.208 ± 0.024	2.427LysPro: 2.427 ± 0.023	2.866LysGln: 2.866 ± 0.022	3.874LysArg: 3.874 ± 0.025	4.633LysSer: 4.633 ± 0.025	3.02LysThr: 3.02 ± 0.023	3.371LysVal: 3.371 ± 0.021	0.737LysTrp: 0.737 ± 0.01	1.85LysTyr: 1.85 ± 0.015	0.001LysXaa: 0.001 ± 0.0
Leu	6.053LeuAla: 6.053 ± 0.03	2.475LeuCys: 2.475 ± 0.021	4.534LeuAsp: 4.534 ± 0.028	5.826LeuGlu: 5.826 ± 0.038	4.646LeuPhe: 4.646 ± 0.032	3.859LeuGly: 3.859 ± 0.022	2.712LeuHis: 2.712 ± 0.022	5.402LeuIle: 5.402 ± 0.031	6.596LeuLys: 6.596 ± 0.036	10.707LeuLeu: 10.707 ± 0.063	2.248LeuMet: 2.248 ± 0.019	5.013LeuAsn: 5.013 ± 0.025	4.771LeuPro: 4.771 ± 0.029	4.509LeuGln: 4.509 ± 0.028	5.497LeuArg: 5.497 ± 0.031	7.672LeuSer: 7.672 ± 0.039	5.032LeuThr: 5.032 ± 0.022	5.551LeuVal: 5.551 ± 0.035	1.075LeuTrp: 1.075 ± 0.013	2.957LeuTyr: 2.957 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	1.594MetAla: 1.594 ± 0.014	0.497MetCys: 0.497 ± 0.007	1.282MetAsp: 1.282 ± 0.012	1.666MetGlu: 1.666 ± 0.014	1.018MetPhe: 1.018 ± 0.013	0.917MetGly: 0.917 ± 0.011	0.65MetHis: 0.65 ± 0.009	1.33MetIle: 1.33 ± 0.011	1.751MetLys: 1.751 ± 0.017	2.491MetLeu: 2.491 ± 0.016	0.673MetMet: 0.673 ± 0.01	1.369MetAsn: 1.369 ± 0.013	1.126MetPro: 1.126 ± 0.014	1.161MetGln: 1.161 ± 0.014	1.28MetArg: 1.28 ± 0.014	1.705MetSer: 1.705 ± 0.016	1.246MetThr: 1.246 ± 0.014	1.39MetVal: 1.39 ± 0.013	0.236MetTrp: 0.236 ± 0.006	0.674MetTyr: 0.674 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.217AsnAla: 3.217 ± 0.019	1.437AsnCys: 1.437 ± 0.013	2.8AsnAsp: 2.8 ± 0.021	3.279AsnGlu: 3.279 ± 0.022	2.534AsnPhe: 2.534 ± 0.019	3.023AsnGly: 3.023 ± 0.026	1.045AsnHis: 1.045 ± 0.013	2.716AsnIle: 2.716 ± 0.021	2.554AsnLys: 2.554 ± 0.02	4.553AsnLeu: 4.553 ± 0.026	1.158AsnMet: 1.158 ± 0.011	2.986AsnAsn: 2.986 ± 0.034	1.928AsnPro: 1.928 ± 0.017	1.798AsnGln: 1.798 ± 0.016	2.637AsnArg: 2.637 ± 0.019	4.313AsnSer: 4.313 ± 0.028	2.264AsnThr: 2.264 ± 0.015	3.476AsnVal: 3.476 ± 0.02	0.617AsnTrp: 0.617 ± 0.01	1.712AsnTyr: 1.712 ± 0.016	0.001AsnXaa: 0.001 ± 0.0
Pro	2.891ProAla: 2.891 ± 0.024	0.925ProCys: 0.925 ± 0.014	2.263ProAsp: 2.263 ± 0.019	2.589ProGlu: 2.589 ± 0.023	1.963ProPhe: 1.963 ± 0.017	2.386ProGly: 2.386 ± 0.052	0.927ProHis: 0.927 ± 0.012	2.144ProIle: 2.144 ± 0.019	2.336ProLys: 2.336 ± 0.022	4.082ProLeu: 4.082 ± 0.024	0.936ProMet: 0.936 ± 0.01	2.103ProAsn: 2.103 ± 0.018	2.982ProPro: 2.982 ± 0.041	1.489ProGln: 1.489 ± 0.017	1.935ProArg: 1.935 ± 0.016	3.823ProSer: 3.823 ± 0.03	2.657ProThr: 2.657 ± 0.023	3.195ProVal: 3.195 ± 0.025	0.48ProTrp: 0.48 ± 0.008	1.35ProTyr: 1.35 ± 0.016	0.001ProXaa: 0.001 ± 0.0
Gln	2.615GlnAla: 2.615 ± 0.02	1.14GlnCys: 1.14 ± 0.016	1.47GlnAsp: 1.47 ± 0.011	2.18GlnGlu: 2.18 ± 0.017	1.953GlnPhe: 1.953 ± 0.016	1.464GlnGly: 1.464 ± 0.015	1.222GlnHis: 1.222 ± 0.015	2.427GlnIle: 2.427 ± 0.018	2.481GlnLys: 2.481 ± 0.022	4.877GlnLeu: 4.877 ± 0.032	1.206GlnMet: 1.206 ± 0.014	2.084GlnAsn: 2.084 ± 0.018	1.893GlnPro: 1.893 ± 0.02	3.607GlnGln: 3.607 ± 0.072	2.649GlnArg: 2.649 ± 0.021	3.302GlnSer: 3.302 ± 0.023	2.107GlnThr: 2.107 ± 0.018	2.112GlnVal: 2.112 ± 0.019	0.599GlnTrp: 0.599 ± 0.01	1.282GlnTyr: 1.282 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	3.042ArgAla: 3.042 ± 0.023	1.626ArgCys: 1.626 ± 0.021	2.438ArgAsp: 2.438 ± 0.019	3.013ArgGlu: 3.013 ± 0.026	2.594ArgPhe: 2.594 ± 0.019	2.478ArgGly: 2.478 ± 0.023	1.532ArgHis: 1.532 ± 0.015	3.23ArgIle: 3.23 ± 0.02	3.763ArgLys: 3.763 ± 0.028	5.882ArgLeu: 5.882 ± 0.037	1.468ArgMet: 1.468 ± 0.016	2.754ArgAsn: 2.754 ± 0.019	2.361ArgPro: 2.361 ± 0.022	2.594ArgGln: 2.594 ± 0.018	4.667ArgArg: 4.667 ± 0.039	4.505ArgSer: 4.505 ± 0.03	2.786ArgThr: 2.786 ± 0.021	2.954ArgVal: 2.954 ± 0.021	0.806ArgTrp: 0.806 ± 0.012	1.708ArgTyr: 1.708 ± 0.014	0.001ArgXaa: 0.001 ± 0.0
Ser	5.546SerAla: 5.546 ± 0.034	2.076SerCys: 2.076 ± 0.019	4.515SerAsp: 4.515 ± 0.033	4.931SerGlu: 4.931 ± 0.031	3.633SerPhe: 3.633 ± 0.024	4.586SerGly: 4.586 ± 0.028	1.628SerHis: 1.628 ± 0.015	4.19SerIle: 4.19 ± 0.024	4.666SerLys: 4.666 ± 0.029	7.474SerLeu: 7.474 ± 0.034	1.818SerMet: 1.818 ± 0.016	4.207SerAsn: 4.207 ± 0.026	3.563SerPro: 3.563 ± 0.031	2.825SerGln: 2.825 ± 0.02	4.354SerArg: 4.354 ± 0.031	9.641SerSer: 9.641 ± 0.069	5.22SerThr: 5.22 ± 0.032	5.727SerVal: 5.727 ± 0.029	0.931SerTrp: 0.931 ± 0.013	2.199SerTyr: 2.199 ± 0.02	0.002SerXaa: 0.002 ± 0.0
Thr	4.123ThrAla: 4.123 ± 0.026	1.307ThrCys: 1.307 ± 0.019	2.809ThrAsp: 2.809 ± 0.019	3.158ThrGlu: 3.158 ± 0.024	2.417ThrPhe: 2.417 ± 0.018	2.891ThrGly: 2.891 ± 0.021	0.956ThrHis: 0.956 ± 0.011	2.873ThrIle: 2.873 ± 0.022	2.751ThrLys: 2.751 ± 0.017	5.008ThrLeu: 5.008 ± 0.027	1.267ThrMet: 1.267 ± 0.013	2.469ThrAsn: 2.469 ± 0.019	2.378ThrPro: 2.378 ± 0.021	1.482ThrGln: 1.482 ± 0.014	2.234ThrArg: 2.234 ± 0.018	4.539ThrSer: 4.539 ± 0.031	3.943ThrThr: 3.943 ± 0.047	4.436ThrVal: 4.436 ± 0.027	0.564ThrTrp: 0.564 ± 0.01	1.399ThrTyr: 1.399 ± 0.014	0.001ThrXaa: 0.001 ± 0.0
Val	4.236ValAla: 4.236 ± 0.025	1.656ValCys: 1.656 ± 0.02	4.146ValAsp: 4.146 ± 0.025	4.682ValGlu: 4.682 ± 0.031	2.633ValPhe: 2.633 ± 0.019	3.403ValGly: 3.403 ± 0.024	1.76ValHis: 1.76 ± 0.016	3.543ValIle: 3.543 ± 0.022	3.851ValLys: 3.851 ± 0.023	5.784ValLeu: 5.784 ± 0.028	1.373ValMet: 1.373 ± 0.012	3.065ValAsn: 3.065 ± 0.02	2.752ValPro: 2.752 ± 0.021	2.816ValGln: 2.816 ± 0.02	3.371ValArg: 3.371 ± 0.025	4.819ValSer: 4.819 ± 0.028	3.3ValThr: 3.3 ± 0.026	4.681ValVal: 4.681 ± 0.03	0.748ValTrp: 0.748 ± 0.01	1.883ValTyr: 1.883 ± 0.017	0.001ValXaa: 0.001 ± 0.0
Trp	0.606TrpAla: 0.606 ± 0.01	0.277TrpCys: 0.277 ± 0.006	0.542TrpAsp: 0.542 ± 0.01	0.561TrpGlu: 0.561 ± 0.009	0.56TrpPhe: 0.56 ± 0.01	0.4TrpGly: 0.4 ± 0.007	0.321TrpHis: 0.321 ± 0.007	0.804TrpIle: 0.804 ± 0.012	0.957TrpLys: 0.957 ± 0.012	1.33TrpLeu: 1.33 ± 0.014	0.35TrpMet: 0.35 ± 0.007	0.762TrpAsn: 0.762 ± 0.011	0.522TrpPro: 0.522 ± 0.008	0.554TrpGln: 0.554 ± 0.01	0.742TrpArg: 0.742 ± 0.01	1.019TrpSer: 1.019 ± 0.015	0.695TrpThr: 0.695 ± 0.011	0.52TrpVal: 0.52 ± 0.008	0.186TrpTrp: 0.186 ± 0.005	0.422TrpTyr: 0.422 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.892TyrAla: 1.892 ± 0.015	0.997TyrCys: 0.997 ± 0.014	1.64TyrAsp: 1.64 ± 0.015	1.82TyrGlu: 1.82 ± 0.015	1.769TyrPhe: 1.769 ± 0.018	1.785TyrGly: 1.785 ± 0.017	0.813TyrHis: 0.813 ± 0.01	1.59TyrIle: 1.59 ± 0.015	1.65TyrLys: 1.65 ± 0.018	3.029TyrLeu: 3.029 ± 0.023	0.697TyrMet: 0.697 ± 0.008	1.481TyrAsn: 1.481 ± 0.016	1.317TyrPro: 1.317 ± 0.015	1.173TyrGln: 1.173 ± 0.012	1.771TyrArg: 1.771 ± 0.016	2.483TyrSer: 2.483 ± 0.018	1.437TyrThr: 1.437 ± 0.016	1.877TyrVal: 1.877 ± 0.015	0.443TyrTrp: 0.443 ± 0.009	1.251TyrTyr: 1.251 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.023XaaXaa: 0.023 ± 0.006

Statistics based on 16597 proteins (8169530 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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