Amino acid dipepetide frequency for Citrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.1AlaAla: 6.1 ± 0.032	1.283AlaCys: 1.283 ± 0.01	3.092AlaAsp: 3.092 ± 0.015	4.019AlaGlu: 4.019 ± 0.02	2.81AlaPhe: 2.81 ± 0.016	3.99AlaGly: 3.99 ± 0.02	1.274AlaHis: 1.274 ± 0.009	3.834AlaIle: 3.834 ± 0.019	3.804AlaLys: 3.804 ± 0.021	6.715AlaLeu: 6.715 ± 0.029	1.75AlaMet: 1.75 ± 0.012	2.696AlaAsn: 2.696 ± 0.013	2.581AlaPro: 2.581 ± 0.016	2.025AlaGln: 2.025 ± 0.013	3.244AlaArg: 3.244 ± 0.016	5.879AlaSer: 5.879 ± 0.022	3.491AlaThr: 3.491 ± 0.018	4.711AlaVal: 4.711 ± 0.023	0.796AlaTrp: 0.796 ± 0.008	1.84AlaTyr: 1.84 ± 0.013	0.0AlaXaa: 0.0 ± 0.0
Cys	1.004CysAla: 1.004 ± 0.008	0.577CysCys: 0.577 ± 0.007	0.927CysAsp: 0.927 ± 0.009	0.933CysGlu: 0.933 ± 0.008	0.944CysPhe: 0.944 ± 0.01	1.426CysGly: 1.426 ± 0.012	0.482CysHis: 0.482 ± 0.007	1.069CysIle: 1.069 ± 0.009	1.217CysLys: 1.217 ± 0.011	2.06CysLeu: 2.06 ± 0.013	0.458CysMet: 0.458 ± 0.006	0.928CysAsn: 0.928 ± 0.008	0.969CysPro: 0.969 ± 0.011	0.648CysGln: 0.648 ± 0.007	1.072CysArg: 1.072 ± 0.009	1.887CysSer: 1.887 ± 0.011	0.883CysThr: 0.883 ± 0.008	1.099CysVal: 1.099 ± 0.009	0.278CysTrp: 0.278 ± 0.004	0.593CysTyr: 0.593 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	3.33AspAla: 3.33 ± 0.016	1.049AspCys: 1.049 ± 0.01	3.463AspAsp: 3.463 ± 0.022	3.799AspGlu: 3.799 ± 0.019	2.369AspPhe: 2.369 ± 0.013	3.588AspGly: 3.588 ± 0.018	1.196AspHis: 1.196 ± 0.01	3.092AspIle: 3.092 ± 0.016	2.653AspLys: 2.653 ± 0.013	5.205AspLeu: 5.205 ± 0.024	1.32AspMet: 1.32 ± 0.01	2.174AspAsn: 2.174 ± 0.013	2.428AspPro: 2.428 ± 0.014	1.74AspGln: 1.74 ± 0.013	2.311AspArg: 2.311 ± 0.016	4.099AspSer: 4.099 ± 0.021	2.131AspThr: 2.131 ± 0.013	3.602AspVal: 3.602 ± 0.016	0.729AspTrp: 0.729 ± 0.006	1.516AspTyr: 1.516 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	4.569GluAla: 4.569 ± 0.023	0.959GluCys: 0.959 ± 0.009	3.719GluAsp: 3.719 ± 0.022	5.724GluGlu: 5.724 ± 0.032	2.432GluPhe: 2.432 ± 0.012	3.598GluGly: 3.598 ± 0.018	1.214GluHis: 1.214 ± 0.009	4.025GluIle: 4.025 ± 0.019	4.588GluLys: 4.588 ± 0.027	6.174GluLeu: 6.174 ± 0.025	1.757GluMet: 1.757 ± 0.013	3.197GluAsn: 3.197 ± 0.019	2.0GluPro: 2.0 ± 0.012	2.074GluGln: 2.074 ± 0.014	3.297GluArg: 3.297 ± 0.02	4.486GluSer: 4.486 ± 0.024	2.952GluThr: 2.952 ± 0.015	4.062GluVal: 4.062 ± 0.018	0.719GluTrp: 0.719 ± 0.007	1.686GluTyr: 1.686 ± 0.011	0.001GluXaa: 0.001 ± 0.0
Phe	2.584PheAla: 2.584 ± 0.014	0.987PheCys: 0.987 ± 0.009	2.47PheAsp: 2.47 ± 0.013	2.352PheGlu: 2.352 ± 0.014	2.1PhePhe: 2.1 ± 0.015	3.203PheGly: 3.203 ± 0.019	1.113PheHis: 1.113 ± 0.009	2.244PheIle: 2.244 ± 0.013	2.229PheLys: 2.229 ± 0.014	4.533PheLeu: 4.533 ± 0.023	0.965PheMet: 0.965 ± 0.008	1.984PheAsn: 1.984 ± 0.011	2.152PhePro: 2.152 ± 0.013	1.611PheGln: 1.611 ± 0.009	2.075PheArg: 2.075 ± 0.012	4.353PheSer: 4.353 ± 0.021	2.107PheThr: 2.107 ± 0.015	2.857PheVal: 2.857 ± 0.016	0.616PheTrp: 0.616 ± 0.007	1.345PheTyr: 1.345 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	3.673GlyAla: 3.673 ± 0.019	1.331GlyCys: 1.331 ± 0.011	3.252GlyAsp: 3.252 ± 0.015	3.568GlyGlu: 3.568 ± 0.018	3.206GlyPhe: 3.206 ± 0.017	4.739GlyGly: 4.739 ± 0.03	1.478GlyHis: 1.478 ± 0.011	3.73GlyIle: 3.73 ± 0.016	4.038GlyLys: 4.038 ± 0.02	6.032GlyLeu: 6.032 ± 0.022	1.512GlyMet: 1.512 ± 0.01	3.424GlyAsn: 3.424 ± 0.02	2.358GlyPro: 2.358 ± 0.016	2.088GlyGln: 2.088 ± 0.014	3.4GlyArg: 3.4 ± 0.018	5.809GlySer: 5.809 ± 0.025	3.205GlyThr: 3.205 ± 0.018	4.081GlyVal: 4.081 ± 0.022	0.877GlyTrp: 0.877 ± 0.009	2.074GlyTyr: 2.074 ± 0.014	0.001GlyXaa: 0.001 ± 0.0
His	1.355HisAla: 1.355 ± 0.01	0.561HisCys: 0.561 ± 0.008	1.124HisAsp: 1.124 ± 0.009	1.235HisGlu: 1.235 ± 0.009	1.14HisPhe: 1.14 ± 0.008	1.609HisGly: 1.609 ± 0.013	0.893HisHis: 0.893 ± 0.01	1.265HisIle: 1.265 ± 0.009	1.16HisLys: 1.16 ± 0.01	2.539HisLeu: 2.539 ± 0.018	0.525HisMet: 0.525 ± 0.006	1.054HisAsn: 1.054 ± 0.009	1.242HisPro: 1.242 ± 0.009	1.046HisGln: 1.046 ± 0.009	1.338HisArg: 1.338 ± 0.01	1.888HisSer: 1.888 ± 0.011	0.908HisThr: 0.908 ± 0.008	1.532HisVal: 1.532 ± 0.011	0.31HisTrp: 0.31 ± 0.004	0.717HisTyr: 0.717 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.695IleAla: 3.695 ± 0.019	1.179IleCys: 1.179 ± 0.011	2.976IleAsp: 2.976 ± 0.014	3.262IleGlu: 3.262 ± 0.017	2.534IlePhe: 2.534 ± 0.016	3.607IleGly: 3.607 ± 0.019	1.327IleHis: 1.327 ± 0.011	3.061IleIle: 3.061 ± 0.017	3.015IleLys: 3.015 ± 0.017	5.616IleLeu: 5.616 ± 0.023	1.204IleMet: 1.204 ± 0.01	2.431IleAsn: 2.431 ± 0.016	3.394IlePro: 3.394 ± 0.023	1.966IleGln: 1.966 ± 0.012	2.695IleArg: 2.695 ± 0.013	5.128IleSer: 5.128 ± 0.021	2.637IleThr: 2.637 ± 0.014	3.576IleVal: 3.576 ± 0.017	0.777IleTrp: 0.777 ± 0.008	1.592IleTyr: 1.592 ± 0.011	0.0IleXaa: 0.0 ± 0.0
Lys	3.973LysAla: 3.973 ± 0.019	1.031LysCys: 1.031 ± 0.009	3.153LysAsp: 3.153 ± 0.017	4.482LysGlu: 4.482 ± 0.024	2.382LysPhe: 2.382 ± 0.012	3.473LysGly: 3.473 ± 0.019	1.323LysHis: 1.323 ± 0.01	3.5LysIle: 3.5 ± 0.017	4.549LysLys: 4.549 ± 0.023	6.506LysLeu: 6.506 ± 0.024	1.531LysMet: 1.531 ± 0.011	2.84LysAsn: 2.84 ± 0.015	2.581LysPro: 2.581 ± 0.017	2.302LysGln: 2.302 ± 0.013	3.504LysArg: 3.504 ± 0.017	4.698LysSer: 4.698 ± 0.022	2.764LysThr: 2.764 ± 0.015	3.744LysVal: 3.744 ± 0.016	0.789LysTrp: 0.789 ± 0.007	1.647LysTyr: 1.647 ± 0.011	0.001LysXaa: 0.001 ± 0.0
Leu	6.621LeuAla: 6.621 ± 0.023	1.998LeuCys: 1.998 ± 0.013	5.34LeuAsp: 5.34 ± 0.024	6.729LeuGlu: 6.729 ± 0.033	4.133LeuPhe: 4.133 ± 0.021	5.948LeuGly: 5.948 ± 0.023	2.657LeuHis: 2.657 ± 0.016	5.011LeuIle: 5.011 ± 0.021	6.697LeuLys: 6.697 ± 0.028	10.429LeuLeu: 10.429 ± 0.039	2.21LeuMet: 2.21 ± 0.015	4.38LeuAsn: 4.38 ± 0.022	5.338LeuPro: 5.338 ± 0.028	4.524LeuGln: 4.524 ± 0.023	5.59LeuArg: 5.59 ± 0.022	9.383LeuSer: 9.383 ± 0.044	4.825LeuThr: 4.825 ± 0.022	6.492LeuVal: 6.492 ± 0.025	1.221LeuTrp: 1.221 ± 0.01	2.687LeuTyr: 2.687 ± 0.014	0.001LeuXaa: 0.001 ± 0.0
Met	2.051MetAla: 2.051 ± 0.012	0.345MetCys: 0.345 ± 0.005	1.33MetAsp: 1.33 ± 0.01	1.902MetGlu: 1.902 ± 0.014	0.851MetPhe: 0.851 ± 0.007	1.604MetGly: 1.604 ± 0.012	0.565MetHis: 0.565 ± 0.007	1.291MetIle: 1.291 ± 0.011	1.665MetLys: 1.665 ± 0.01	2.25MetLeu: 2.25 ± 0.012	0.669MetMet: 0.669 ± 0.007	1.065MetAsn: 1.065 ± 0.009	1.117MetPro: 1.117 ± 0.01	0.933MetGln: 0.933 ± 0.009	1.154MetArg: 1.154 ± 0.01	1.78MetSer: 1.78 ± 0.011	1.072MetThr: 1.072 ± 0.008	1.548MetVal: 1.548 ± 0.011	0.268MetTrp: 0.268 ± 0.004	0.593MetTyr: 0.593 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.692AsnAla: 2.692 ± 0.013	0.978AsnCys: 0.978 ± 0.009	2.209AsnAsp: 2.209 ± 0.013	2.673AsnGlu: 2.673 ± 0.014	2.251AsnPhe: 2.251 ± 0.013	3.279AsnGly: 3.279 ± 0.018	1.114AsnHis: 1.114 ± 0.01	2.692AsnIle: 2.692 ± 0.014	2.628AsnLys: 2.628 ± 0.013	5.635AsnLeu: 5.635 ± 0.034	1.14AsnMet: 1.14 ± 0.008	2.85AsnAsn: 2.85 ± 0.025	2.292AsnPro: 2.292 ± 0.014	1.798AsnGln: 1.798 ± 0.013	2.06AsnArg: 2.06 ± 0.011	4.146AsnSer: 4.146 ± 0.019	1.95AsnThr: 1.95 ± 0.011	2.885AsnVal: 2.885 ± 0.015	0.603AsnTrp: 0.603 ± 0.006	1.37AsnTyr: 1.37 ± 0.011	0.001AsnXaa: 0.001 ± 0.0
Pro	2.945ProAla: 2.945 ± 0.015	0.774ProCys: 0.774 ± 0.008	2.362ProAsp: 2.362 ± 0.014	3.084ProGlu: 3.084 ± 0.015	1.987ProPhe: 1.987 ± 0.013	2.561ProGly: 2.561 ± 0.016	1.096ProHis: 1.096 ± 0.01	2.358ProIle: 2.358 ± 0.014	2.694ProLys: 2.694 ± 0.015	4.264ProLeu: 4.264 ± 0.017	0.911ProMet: 0.911 ± 0.009	2.315ProAsn: 2.315 ± 0.015	3.295ProPro: 3.295 ± 0.033	1.772ProGln: 1.772 ± 0.014	2.28ProArg: 2.28 ± 0.016	4.98ProSer: 4.98 ± 0.024	2.476ProThr: 2.476 ± 0.014	2.948ProVal: 2.948 ± 0.017	0.581ProTrp: 0.581 ± 0.007	1.275ProTyr: 1.275 ± 0.01	0.001ProXaa: 0.001 ± 0.0
Gln	2.299GlnAla: 2.299 ± 0.015	0.603GlnCys: 0.603 ± 0.007	1.619GlnAsp: 1.619 ± 0.011	2.366GlnGlu: 2.366 ± 0.015	1.457GlnPhe: 1.457 ± 0.012	2.1GlnGly: 2.1 ± 0.013	0.932GlnHis: 0.932 ± 0.007	2.077GlnIle: 2.077 ± 0.013	2.259GlnLys: 2.259 ± 0.013	3.937GlnLeu: 3.937 ± 0.02	0.953GlnMet: 0.953 ± 0.009	1.905GlnAsn: 1.905 ± 0.011	1.656GlnPro: 1.656 ± 0.015	1.991GlnGln: 1.991 ± 0.018	2.058GlnArg: 2.058 ± 0.011	2.857GlnSer: 2.857 ± 0.014	1.675GlnThr: 1.675 ± 0.01	2.34GlnVal: 2.34 ± 0.013	0.449GlnTrp: 0.449 ± 0.006	0.94GlnTyr: 0.94 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	3.144ArgAla: 3.144 ± 0.016	0.959ArgCys: 0.959 ± 0.008	2.552ArgAsp: 2.552 ± 0.015	3.249ArgGlu: 3.249 ± 0.022	2.229ArgPhe: 2.229 ± 0.013	3.054ArgGly: 3.054 ± 0.017	1.251ArgHis: 1.251 ± 0.011	2.992ArgIle: 2.992 ± 0.016	3.603ArgLys: 3.603 ± 0.018	5.202ArgLeu: 5.202 ± 0.022	1.283ArgMet: 1.283 ± 0.009	2.576ArgAsn: 2.576 ± 0.014	2.197ArgPro: 2.197 ± 0.015	1.81ArgGln: 1.81 ± 0.011	3.636ArgArg: 3.636 ± 0.019	4.13ArgSer: 4.13 ± 0.02	2.361ArgThr: 2.361 ± 0.014	3.243ArgVal: 3.243 ± 0.013	0.719ArgTrp: 0.719 ± 0.007	1.451ArgTyr: 1.451 ± 0.01	0.001ArgXaa: 0.001 ± 0.0
Ser	5.259SerAla: 5.259 ± 0.02	1.828SerCys: 1.828 ± 0.012	4.179SerAsp: 4.179 ± 0.016	4.663SerGlu: 4.663 ± 0.021	4.268SerPhe: 4.268 ± 0.021	5.856SerGly: 5.856 ± 0.026	1.973SerHis: 1.973 ± 0.012	4.79SerIle: 4.79 ± 0.022	4.988SerLys: 4.988 ± 0.019	9.446SerLeu: 9.446 ± 0.041	2.105SerMet: 2.105 ± 0.013	4.331SerAsn: 4.331 ± 0.021	4.151SerPro: 4.151 ± 0.025	2.973SerGln: 2.973 ± 0.018	4.403SerArg: 4.403 ± 0.019	10.753SerSer: 10.753 ± 0.042	4.563SerThr: 4.563 ± 0.019	5.27SerVal: 5.27 ± 0.019	1.196SerTrp: 1.196 ± 0.011	2.388SerTyr: 2.388 ± 0.014	0.001SerXaa: 0.001 ± 0.0
Thr	3.343ThrAla: 3.343 ± 0.017	0.938ThrCys: 0.938 ± 0.008	2.229ThrAsp: 2.229 ± 0.013	2.757ThrGlu: 2.757 ± 0.015	2.083ThrPhe: 2.083 ± 0.014	3.229ThrGly: 3.229 ± 0.019	1.034ThrHis: 1.034 ± 0.008	2.819ThrIle: 2.819 ± 0.016	2.612ThrLys: 2.612 ± 0.014	4.736ThrLeu: 4.736 ± 0.021	1.131ThrMet: 1.131 ± 0.01	2.166ThrAsn: 2.166 ± 0.012	2.385ThrPro: 2.385 ± 0.016	1.505ThrGln: 1.505 ± 0.01	2.303ThrArg: 2.303 ± 0.015	4.531ThrSer: 4.531 ± 0.021	2.78ThrThr: 2.78 ± 0.017	3.329ThrVal: 3.329 ± 0.018	0.644ThrTrp: 0.644 ± 0.007	1.368ThrTyr: 1.368 ± 0.012	0.0ThrXaa: 0.0 ± 0.0
Val	4.754ValAla: 4.754 ± 0.017	1.151ValCys: 1.151 ± 0.009	3.626ValAsp: 3.626 ± 0.018	4.087ValGlu: 4.087 ± 0.019	2.745ValPhe: 2.745 ± 0.015	4.128ValGly: 4.128 ± 0.022	1.521ValHis: 1.521 ± 0.012	3.528ValIle: 3.528 ± 0.016	3.844ValLys: 3.844 ± 0.016	6.578ValLeu: 6.578 ± 0.026	1.503ValMet: 1.503 ± 0.009	2.75ValAsn: 2.75 ± 0.015	3.097ValPro: 3.097 ± 0.016	2.271ValGln: 2.271 ± 0.012	2.984ValArg: 2.984 ± 0.015	5.368ValSer: 5.368 ± 0.019	3.226ValThr: 3.226 ± 0.015	4.726ValVal: 4.726 ± 0.021	0.761ValTrp: 0.761 ± 0.008	1.96ValTyr: 1.96 ± 0.012	0.001ValXaa: 0.001 ± 0.0
Trp	0.785TrpAla: 0.785 ± 0.007	0.254TrpCys: 0.254 ± 0.004	0.646TrpAsp: 0.646 ± 0.007	0.769TrpGlu: 0.769 ± 0.008	0.569TrpPhe: 0.569 ± 0.006	0.751TrpGly: 0.751 ± 0.008	0.297TrpHis: 0.297 ± 0.005	0.761TrpIle: 0.761 ± 0.007	0.996TrpLys: 0.996 ± 0.008	1.331TrpLeu: 1.331 ± 0.01	0.35TrpMet: 0.35 ± 0.005	0.727TrpAsn: 0.727 ± 0.009	0.5TrpPro: 0.5 ± 0.006	0.464TrpGln: 0.464 ± 0.007	0.818TrpArg: 0.818 ± 0.008	0.955TrpSer: 0.955 ± 0.009	0.638TrpThr: 0.638 ± 0.008	0.807TrpVal: 0.807 ± 0.008	0.231TrpTrp: 0.231 ± 0.004	0.344TrpTyr: 0.344 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.757TyrAla: 1.757 ± 0.014	0.669TyrCys: 0.669 ± 0.007	1.526TyrAsp: 1.526 ± 0.012	1.58TyrGlu: 1.58 ± 0.01	1.389TyrPhe: 1.389 ± 0.012	2.133TyrGly: 2.133 ± 0.013	0.699TyrHis: 0.699 ± 0.008	1.531TyrIle: 1.531 ± 0.011	1.536TyrLys: 1.536 ± 0.011	3.023TyrLeu: 3.023 ± 0.018	0.777TyrMet: 0.777 ± 0.008	1.453TyrAsn: 1.453 ± 0.012	1.227TyrPro: 1.227 ± 0.009	0.933TyrGln: 0.933 ± 0.009	1.417TyrArg: 1.417 ± 0.01	2.272TyrSer: 2.272 ± 0.015	1.28TyrThr: 1.28 ± 0.01	1.758TyrVal: 1.758 ± 0.012	0.427TyrTrp: 0.427 ± 0.006	0.972TyrTyr: 0.972 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.083XaaXaa: 0.083 ± 0.012

Statistics based on 35792 proteins (14900710 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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