Amino acid dipepetide frequency for Canary polyomavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.382AlaAla: 7.382 ± 4.085
0.568AlaCys: 0.568 ± 0.435
5.679AlaAsp: 5.679 ± 1.083
9.086AlaGlu: 9.086 ± 2.234
2.271AlaPhe: 2.271 ± 0.839
6.814AlaGly: 6.814 ± 1.344
0.0AlaHis: 0.0 ± 0.0
3.407AlaIle: 3.407 ± 1.347
1.704AlaLys: 1.704 ± 0.869
8.518AlaLeu: 8.518 ± 1.284
0.568AlaMet: 0.568 ± 0.435
2.271AlaAsn: 2.271 ± 0.647
2.271AlaPro: 2.271 ± 1.319
1.704AlaGln: 1.704 ± 0.477
1.136AlaArg: 1.136 ± 0.488
2.839AlaSer: 2.839 ± 1.351
5.679AlaThr: 5.679 ± 2.73
6.246AlaVal: 6.246 ± 0.864
1.136AlaTrp: 1.136 ± 0.818
5.111AlaTyr: 5.111 ± 0.924
0.0AlaXaa: 0.0 ± 0.0
Cys
2.839CysAla: 2.839 ± 1.589
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.568CysGlu: 0.568 ± 0.654
1.136CysPhe: 1.136 ± 0.871
0.568CysGly: 0.568 ± 0.484
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.136CysLys: 1.136 ± 0.488
1.704CysLeu: 1.704 ± 0.977
0.568CysMet: 0.568 ± 0.435
2.271CysAsn: 2.271 ± 1.337
1.136CysPro: 1.136 ± 0.488
0.568CysGln: 0.568 ± 0.435
0.568CysArg: 0.568 ± 0.435
0.0CysSer: 0.0 ± 0.0
1.704CysThr: 1.704 ± 1.306
0.568CysVal: 0.568 ± 0.435
0.0CysTrp: 0.0 ± 0.0
0.568CysTyr: 0.568 ± 0.484
0.0CysXaa: 0.0 ± 0.0
Asp
2.271AspAla: 2.271 ± 0.856
1.136AspCys: 1.136 ± 0.871
1.136AspAsp: 1.136 ± 0.488
3.407AspGlu: 3.407 ± 1.493
1.704AspPhe: 1.704 ± 0.595
1.704AspGly: 1.704 ± 0.869
1.136AspHis: 1.136 ± 0.871
4.543AspIle: 4.543 ± 0.896
3.407AspLys: 3.407 ± 1.493
4.543AspLeu: 4.543 ± 1.001
1.704AspMet: 1.704 ± 0.884
2.839AspAsn: 2.839 ± 0.928
6.246AspPro: 6.246 ± 0.918
2.839AspGln: 2.839 ± 0.821
2.271AspArg: 2.271 ± 0.647
2.271AspSer: 2.271 ± 1.319
0.568AspThr: 0.568 ± 0.435
2.271AspVal: 2.271 ± 0.976
2.271AspTrp: 2.271 ± 1.636
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
6.246GluAla: 6.246 ± 2.103
1.136GluCys: 1.136 ± 0.871
3.975GluAsp: 3.975 ± 1.772
3.975GluGlu: 3.975 ± 1.952
1.704GluPhe: 1.704 ± 0.977
7.382GluGly: 7.382 ± 1.153
1.704GluHis: 1.704 ± 0.595
1.136GluIle: 1.136 ± 0.871
2.271GluLys: 2.271 ± 1.337
4.543GluLeu: 4.543 ± 1.214
1.136GluMet: 1.136 ± 0.481
4.543GluAsn: 4.543 ± 1.347
0.568GluPro: 0.568 ± 0.484
4.543GluGln: 4.543 ± 2.15
5.111GluArg: 5.111 ± 1.174
5.111GluSer: 5.111 ± 0.914
4.543GluThr: 4.543 ± 1.114
1.704GluVal: 1.704 ± 1.451
1.136GluTrp: 1.136 ± 0.818
3.407GluTyr: 3.407 ± 0.374
0.0GluXaa: 0.0 ± 0.0
Phe
5.111PheAla: 5.111 ± 1.257
0.568PheCys: 0.568 ± 0.435
1.704PheAsp: 1.704 ± 0.595
2.271PheGlu: 2.271 ± 0.647
0.568PhePhe: 0.568 ± 0.484
3.407PheGly: 3.407 ± 1.152
0.568PheHis: 0.568 ± 0.484
2.271PheIle: 2.271 ± 1.636
2.271PheLys: 2.271 ± 1.416
2.271PheLeu: 2.271 ± 0.647
0.568PheMet: 0.568 ± 0.654
1.136PheAsn: 1.136 ± 0.488
1.704PhePro: 1.704 ± 0.477
0.0PheGln: 0.0 ± 0.0
0.568PheArg: 0.568 ± 0.484
3.407PheSer: 3.407 ± 0.374
2.839PheThr: 2.839 ± 0.827
0.568PheVal: 0.568 ± 0.518
1.136PheTrp: 1.136 ± 0.818
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.679GlyAla: 5.679 ± 2.45
0.568GlyCys: 0.568 ± 0.435
4.543GlyAsp: 4.543 ± 1.059
4.543GlyGlu: 4.543 ± 1.349
0.568GlyPhe: 0.568 ± 0.518
9.086GlyGly: 9.086 ± 2.222
1.136GlyHis: 1.136 ± 0.967
2.839GlyIle: 2.839 ± 1.347
1.704GlyLys: 1.704 ± 0.788
11.357GlyLeu: 11.357 ± 3.926
1.136GlyMet: 1.136 ± 0.871
3.975GlyAsn: 3.975 ± 0.531
5.679GlyPro: 5.679 ± 1.036
2.271GlyGln: 2.271 ± 0.53
3.975GlyArg: 3.975 ± 1.484
7.382GlySer: 7.382 ± 1.342
3.975GlyThr: 3.975 ± 1.693
3.975GlyVal: 3.975 ± 1.712
1.136GlyTrp: 1.136 ± 0.818
5.679GlyTyr: 5.679 ± 0.582
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.136HisCys: 1.136 ± 0.708
1.136HisAsp: 1.136 ± 0.871
0.568HisGlu: 0.568 ± 0.518
1.136HisPhe: 1.136 ± 0.488
0.0HisGly: 0.0 ± 0.0
0.568HisHis: 0.568 ± 0.435
0.0HisIle: 0.0 ± 0.0
1.136HisLys: 1.136 ± 0.871
2.839HisLeu: 2.839 ± 1.589
0.0HisMet: 0.0 ± 0.0
0.568HisAsn: 0.568 ± 0.484
1.704HisPro: 1.704 ± 0.977
0.568HisGln: 0.568 ± 0.435
0.0HisArg: 0.0 ± 0.0
0.568HisSer: 0.568 ± 0.484
1.136HisThr: 1.136 ± 0.488
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.271HisTyr: 2.271 ± 1.636
0.0HisXaa: 0.0 ± 0.0
Ile
1.704IleAla: 1.704 ± 1.553
1.136IleCys: 1.136 ± 0.488
3.407IleAsp: 3.407 ± 1.191
2.271IleGlu: 2.271 ± 1.176
2.839IlePhe: 2.839 ± 0.812
0.568IleGly: 0.568 ± 0.518
0.0IleHis: 0.0 ± 0.0
2.271IleIle: 2.271 ± 1.138
1.136IleLys: 1.136 ± 0.488
2.839IleLeu: 2.839 ± 0.834
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
1.136IlePro: 1.136 ± 0.708
1.136IleGln: 1.136 ± 0.488
2.839IleArg: 2.839 ± 1.363
5.111IleSer: 5.111 ± 1.83
2.839IleThr: 2.839 ± 1.237
1.136IleVal: 1.136 ± 0.481
1.136IleTrp: 1.136 ± 0.818
1.136IleTyr: 1.136 ± 0.967
0.0IleXaa: 0.0 ± 0.0
Lys
3.975LysAla: 3.975 ± 1.027
0.0LysCys: 0.0 ± 0.0
3.975LysAsp: 3.975 ± 1.232
2.271LysGlu: 2.271 ± 0.856
1.136LysPhe: 1.136 ± 0.708
5.111LysGly: 5.111 ± 1.912
1.136LysHis: 1.136 ± 0.871
2.839LysIle: 2.839 ± 0.399
3.407LysLys: 3.407 ± 0.646
2.271LysLeu: 2.271 ± 0.856
2.271LysMet: 2.271 ± 1.416
1.704LysAsn: 1.704 ± 0.788
0.568LysPro: 0.568 ± 0.484
2.839LysGln: 2.839 ± 0.656
6.246LysArg: 6.246 ± 1.451
3.975LysSer: 3.975 ± 1.018
2.271LysThr: 2.271 ± 0.976
1.704LysVal: 1.704 ± 0.977
0.0LysTrp: 0.0 ± 0.0
0.568LysTyr: 0.568 ± 0.435
0.0LysXaa: 0.0 ± 0.0
Leu
7.95LeuAla: 7.95 ± 2.343
1.136LeuCys: 1.136 ± 0.488
4.543LeuAsp: 4.543 ± 0.945
3.975LeuGlu: 3.975 ± 1.164
2.271LeuPhe: 2.271 ± 0.624
7.95LeuGly: 7.95 ± 2.485
1.704LeuHis: 1.704 ± 1.306
3.407LeuIle: 3.407 ± 1.289
5.679LeuLys: 5.679 ± 0.735
16.468LeuLeu: 16.468 ± 5.58
1.704LeuMet: 1.704 ± 1.142
9.086LeuAsn: 9.086 ± 2.303
9.654LeuPro: 9.654 ± 1.958
6.246LeuGln: 6.246 ± 1.994
3.975LeuArg: 3.975 ± 1.027
3.975LeuSer: 3.975 ± 1.232
9.086LeuThr: 9.086 ± 2.539
2.271LeuVal: 2.271 ± 1.138
0.568LeuTrp: 0.568 ± 0.518
3.407LeuTyr: 3.407 ± 1.933
0.0LeuXaa: 0.0 ± 0.0
Met
2.271MetAla: 2.271 ± 0.996
0.0MetCys: 0.0 ± 0.0
1.704MetAsp: 1.704 ± 1.292
1.704MetGlu: 1.704 ± 0.977
0.568MetPhe: 0.568 ± 0.435
2.839MetGly: 2.839 ± 0.834
1.136MetHis: 1.136 ± 0.708
0.0MetIle: 0.0 ± 0.0
2.271MetLys: 2.271 ± 1.416
2.839MetLeu: 2.839 ± 1.589
0.568MetMet: 0.568 ± 0.484
0.0MetAsn: 0.0 ± 0.0
1.704MetPro: 1.704 ± 0.681
0.568MetGln: 0.568 ± 0.484
0.568MetArg: 0.568 ± 0.654
1.136MetSer: 1.136 ± 0.759
0.568MetThr: 0.568 ± 0.435
1.704MetVal: 1.704 ± 0.595
0.568MetTrp: 0.568 ± 0.484
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
6.814AsnAla: 6.814 ± 1.531
0.568AsnCys: 0.568 ± 0.435
0.568AsnAsp: 0.568 ± 0.484
3.407AsnGlu: 3.407 ± 1.551
1.136AsnPhe: 1.136 ± 0.488
3.975AsnGly: 3.975 ± 1.39
0.568AsnHis: 0.568 ± 0.435
0.568AsnIle: 0.568 ± 0.518
1.704AsnLys: 1.704 ± 0.595
3.975AsnLeu: 3.975 ± 3.048
1.136AsnMet: 1.136 ± 0.475
2.839AsnAsn: 2.839 ± 1.633
3.975AsnPro: 3.975 ± 1.707
0.568AsnGln: 0.568 ± 0.435
7.382AsnArg: 7.382 ± 4.858
2.839AsnSer: 2.839 ± 0.928
3.407AsnThr: 3.407 ± 1.738
3.407AsnVal: 3.407 ± 0.607
0.568AsnTrp: 0.568 ± 0.435
1.136AsnTyr: 1.136 ± 0.708
0.0AsnXaa: 0.0 ± 0.0
Pro
1.136ProAla: 1.136 ± 0.967
0.568ProCys: 0.568 ± 0.484
7.95ProAsp: 7.95 ± 1.061
6.814ProGlu: 6.814 ± 2.288
0.568ProPhe: 0.568 ± 0.435
3.407ProGly: 3.407 ± 0.374
1.136ProHis: 1.136 ± 0.488
1.136ProIle: 1.136 ± 0.488
3.975ProLys: 3.975 ± 0.664
4.543ProLeu: 4.543 ± 1.347
1.136ProMet: 1.136 ± 0.493
1.704ProAsn: 1.704 ± 0.757
9.654ProPro: 9.654 ± 2.582
0.0ProGln: 0.0 ± 0.0
6.814ProArg: 6.814 ± 1.02
3.407ProSer: 3.407 ± 0.374
2.839ProThr: 2.839 ± 0.821
5.679ProVal: 5.679 ± 1.855
0.568ProTrp: 0.568 ± 0.654
1.704ProTyr: 1.704 ± 0.884
0.0ProXaa: 0.0 ± 0.0
Gln
1.704GlnAla: 1.704 ± 0.595
1.136GlnCys: 1.136 ± 0.708
0.568GlnAsp: 0.568 ± 0.484
1.704GlnGlu: 1.704 ± 0.983
1.136GlnPhe: 1.136 ± 0.488
1.136GlnGly: 1.136 ± 0.671
0.568GlnHis: 0.568 ± 0.435
3.407GlnIle: 3.407 ± 1.659
1.136GlnLys: 1.136 ± 0.871
3.975GlnLeu: 3.975 ± 1.276
2.271GlnMet: 2.271 ± 0.732
2.839GlnAsn: 2.839 ± 0.928
2.271GlnPro: 2.271 ± 0.53
0.568GlnGln: 0.568 ± 0.435
2.839GlnArg: 2.839 ± 0.834
3.407GlnSer: 3.407 ± 1.493
0.0GlnThr: 0.0 ± 0.0
1.704GlnVal: 1.704 ± 0.869
0.0GlnTrp: 0.0 ± 0.0
2.271GlnTyr: 2.271 ± 0.856
0.0GlnXaa: 0.0 ± 0.0
Arg
3.975ArgAla: 3.975 ± 1.163
1.136ArgCys: 1.136 ± 0.871
1.136ArgAsp: 1.136 ± 0.488
3.407ArgGlu: 3.407 ± 1.191
3.407ArgPhe: 3.407 ± 1.659
3.975ArgGly: 3.975 ± 1.018
1.136ArgHis: 1.136 ± 0.794
1.704ArgIle: 1.704 ± 0.788
5.111ArgLys: 5.111 ± 1.262
6.814ArgLeu: 6.814 ± 1.827
2.839ArgMet: 2.839 ± 0.632
5.679ArgAsn: 5.679 ± 0.735
2.839ArgPro: 2.839 ± 1.363
2.271ArgGln: 2.271 ± 0.53
6.814ArgArg: 6.814 ± 2.434
3.407ArgSer: 3.407 ± 1.186
3.407ArgThr: 3.407 ± 0.607
6.246ArgVal: 6.246 ± 0.981
0.0ArgTrp: 0.0 ± 0.0
3.975ArgTyr: 3.975 ± 0.664
0.0ArgXaa: 0.0 ± 0.0
Ser
5.111SerAla: 5.111 ± 1.897
2.271SerCys: 2.271 ± 0.856
2.271SerAsp: 2.271 ± 1.166
4.543SerGlu: 4.543 ± 1.347
0.0SerPhe: 0.0 ± 0.0
9.654SerGly: 9.654 ± 1.691
0.568SerHis: 0.568 ± 0.435
1.136SerIle: 1.136 ± 0.671
2.839SerLys: 2.839 ± 0.834
6.246SerLeu: 6.246 ± 1.169
2.271SerMet: 2.271 ± 1.243
1.704SerAsn: 1.704 ± 0.884
2.271SerPro: 2.271 ± 1.416
4.543SerGln: 4.543 ± 1.464
6.246SerArg: 6.246 ± 1.451
5.111SerSer: 5.111 ± 1.897
5.111SerThr: 5.111 ± 1.085
1.704SerVal: 1.704 ± 0.869
2.271SerTrp: 2.271 ± 0.53
3.407SerTyr: 3.407 ± 0.901
0.0SerXaa: 0.0 ± 0.0
Thr
2.839ThrAla: 2.839 ± 1.613
0.568ThrCys: 0.568 ± 0.435
2.839ThrAsp: 2.839 ± 0.989
4.543ThrGlu: 4.543 ± 0.965
1.136ThrPhe: 1.136 ± 0.818
6.814ThrGly: 6.814 ± 3.226
0.0ThrHis: 0.0 ± 0.0
2.271ThrIle: 2.271 ± 0.62
1.704ThrLys: 1.704 ± 1.306
6.814ThrLeu: 6.814 ± 1.337
1.704ThrMet: 1.704 ± 0.788
2.271ThrAsn: 2.271 ± 1.166
7.95ThrPro: 7.95 ± 1.797
0.568ThrGln: 0.568 ± 0.435
3.407ThrArg: 3.407 ± 0.607
5.679ThrSer: 5.679 ± 2.902
5.111ThrThr: 5.111 ± 1.365
4.543ThrVal: 4.543 ± 1.952
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.407ValAla: 3.407 ± 1.371
1.136ValCys: 1.136 ± 0.871
1.136ValAsp: 1.136 ± 0.871
4.543ValGlu: 4.543 ± 0.965
2.839ValPhe: 2.839 ± 0.614
3.975ValGly: 3.975 ± 2.739
1.136ValHis: 1.136 ± 0.488
1.136ValIle: 1.136 ± 0.488
2.839ValLys: 2.839 ± 1.237
5.111ValLeu: 5.111 ± 1.313
0.0ValMet: 0.0 ± 0.0
3.407ValAsn: 3.407 ± 0.646
1.136ValPro: 1.136 ± 0.488
1.704ValGln: 1.704 ± 0.869
4.543ValArg: 4.543 ± 0.889
5.679ValSer: 5.679 ± 2.01
3.407ValThr: 3.407 ± 1.24
2.839ValVal: 2.839 ± 1.324
0.0ValTrp: 0.0 ± 0.0
1.704ValTyr: 1.704 ± 0.595
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.568TrpCys: 0.568 ± 0.484
0.0TrpAsp: 0.0 ± 0.0
1.704TrpGlu: 1.704 ± 0.884
1.136TrpPhe: 1.136 ± 0.818
1.136TrpGly: 1.136 ± 0.708
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
4.543TrpLeu: 4.543 ± 3.273
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.136TrpGln: 1.136 ± 0.818
0.568TrpArg: 0.568 ± 0.435
0.0TrpSer: 0.0 ± 0.0
0.568TrpThr: 0.568 ± 0.518
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.136TrpTyr: 1.136 ± 0.818
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.975TyrAla: 3.975 ± 1.272
0.568TyrCys: 0.568 ± 0.435
0.0TyrAsp: 0.0 ± 0.0
0.568TyrGlu: 0.568 ± 0.484
5.679TyrPhe: 5.679 ± 1.164
1.704TyrGly: 1.704 ± 0.884
1.136TyrHis: 1.136 ± 0.818
0.568TyrIle: 0.568 ± 0.654
2.839TyrLys: 2.839 ± 0.399
3.407TyrLeu: 3.407 ± 0.607
0.568TyrMet: 0.568 ± 0.654
1.704TyrAsn: 1.704 ± 0.595
2.271TyrPro: 2.271 ± 1.166
0.0TyrGln: 0.0 ± 0.0
3.407TyrArg: 3.407 ± 1.186
3.975TyrSer: 3.975 ± 0.711
1.704TyrThr: 1.704 ± 0.595
3.407TyrVal: 3.407 ± 0.646
0.0TyrTrp: 0.0 ± 0.0
4.543TyrTyr: 4.543 ± 2.15
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1762 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski