Amino acid dipepetide frequency for Cercospora berteroae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.08AlaAla: 10.08 ± 0.069	1.065AlaCys: 1.065 ± 0.015	4.652AlaAsp: 4.652 ± 0.03	5.83AlaGlu: 5.83 ± 0.04	3.245AlaPhe: 3.245 ± 0.025	6.218AlaGly: 6.218 ± 0.039	1.903AlaHis: 1.903 ± 0.018	4.331AlaIle: 4.331 ± 0.028	4.577AlaLys: 4.577 ± 0.037	7.938AlaLeu: 7.938 ± 0.042	2.07AlaMet: 2.07 ± 0.021	3.258AlaAsn: 3.258 ± 0.027	5.137AlaPro: 5.137 ± 0.04	4.005AlaGln: 4.005 ± 0.028	5.246AlaArg: 5.246 ± 0.031	7.514AlaSer: 7.514 ± 0.05	5.765AlaThr: 5.765 ± 0.034	5.559AlaVal: 5.559 ± 0.032	1.23AlaTrp: 1.23 ± 0.015	2.33AlaTyr: 2.33 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	0.935CysAla: 0.935 ± 0.014	0.218CysCys: 0.218 ± 0.007	0.64CysAsp: 0.64 ± 0.01	0.607CysGlu: 0.607 ± 0.01	0.506CysPhe: 0.506 ± 0.01	0.91CysGly: 0.91 ± 0.016	0.308CysHis: 0.308 ± 0.008	0.664CysIle: 0.664 ± 0.01	0.535CysLys: 0.535 ± 0.01	1.114CysLeu: 1.114 ± 0.017	0.255CysMet: 0.255 ± 0.007	0.424CysAsn: 0.424 ± 0.008	0.61CysPro: 0.61 ± 0.012	0.43CysGln: 0.43 ± 0.009	0.693CysArg: 0.693 ± 0.013	0.845CysSer: 0.845 ± 0.013	0.689CysThr: 0.689 ± 0.012	0.755CysVal: 0.755 ± 0.013	0.19CysTrp: 0.19 ± 0.006	0.36CysTyr: 0.36 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.262AspAla: 5.262 ± 0.04	0.633AspCys: 0.633 ± 0.012	4.547AspAsp: 4.547 ± 0.048	4.763AspGlu: 4.763 ± 0.042	2.295AspPhe: 2.295 ± 0.023	4.176AspGly: 4.176 ± 0.031	1.294AspHis: 1.294 ± 0.015	2.855AspIle: 2.855 ± 0.019	2.399AspLys: 2.399 ± 0.022	5.186AspLeu: 5.186 ± 0.035	1.317AspMet: 1.317 ± 0.016	1.881AspAsn: 1.881 ± 0.019	3.207AspPro: 3.207 ± 0.024	2.065AspGln: 2.065 ± 0.022	3.168AspArg: 3.168 ± 0.029	4.043AspSer: 4.043 ± 0.029	3.026AspThr: 3.026 ± 0.023	3.812AspVal: 3.812 ± 0.028	0.956AspTrp: 0.956 ± 0.014	1.627AspTyr: 1.627 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.761GluAla: 5.761 ± 0.04	0.617GluCys: 0.617 ± 0.01	4.582GluAsp: 4.582 ± 0.04	5.591GluGlu: 5.591 ± 0.049	1.855GluPhe: 1.855 ± 0.017	3.897GluGly: 3.897 ± 0.031	1.621GluHis: 1.621 ± 0.015	2.922GluIle: 2.922 ± 0.023	3.778GluLys: 3.778 ± 0.031	5.395GluLeu: 5.395 ± 0.041	1.477GluMet: 1.477 ± 0.015	2.237GluAsn: 2.237 ± 0.021	2.813GluPro: 2.813 ± 0.025	3.062GluGln: 3.062 ± 0.025	4.157GluArg: 4.157 ± 0.036	4.086GluSer: 4.086 ± 0.029	3.445GluThr: 3.445 ± 0.028	3.708GluVal: 3.708 ± 0.03	0.907GluTrp: 0.907 ± 0.012	1.672GluTyr: 1.672 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.249PheAla: 3.249 ± 0.023	0.529PheCys: 0.529 ± 0.01	2.342PheAsp: 2.342 ± 0.021	2.228PheGlu: 2.228 ± 0.021	1.491PhePhe: 1.491 ± 0.02	2.886PheGly: 2.886 ± 0.029	0.862PheHis: 0.862 ± 0.012	1.565PheIle: 1.565 ± 0.022	1.472PheLys: 1.472 ± 0.018	3.107PheLeu: 3.107 ± 0.029	0.769PheMet: 0.769 ± 0.013	1.36PheAsn: 1.36 ± 0.015	1.77PhePro: 1.77 ± 0.019	1.336PheGln: 1.336 ± 0.016	1.878PheArg: 1.878 ± 0.019	2.686PheSer: 2.686 ± 0.023	2.133PheThr: 2.133 ± 0.021	2.348PheVal: 2.348 ± 0.023	0.633PheTrp: 0.633 ± 0.01	1.04PheTyr: 1.04 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	5.618GlyAla: 5.618 ± 0.036	0.827GlyCys: 0.827 ± 0.014	3.74GlyAsp: 3.74 ± 0.03	3.823GlyGlu: 3.823 ± 0.028	2.729GlyPhe: 2.729 ± 0.029	5.963GlyGly: 5.963 ± 0.054	1.74GlyHis: 1.74 ± 0.019	3.404GlyIle: 3.404 ± 0.028	3.614GlyLys: 3.614 ± 0.031	5.938GlyLeu: 5.938 ± 0.034	1.646GlyMet: 1.646 ± 0.022	2.675GlyAsn: 2.675 ± 0.028	3.27GlyPro: 3.27 ± 0.026	2.776GlyGln: 2.776 ± 0.023	4.12GlyArg: 4.12 ± 0.029	5.575GlySer: 5.575 ± 0.04	4.175GlyThr: 4.175 ± 0.031	4.277GlyVal: 4.277 ± 0.031	1.142GlyTrp: 1.142 ± 0.017	2.15GlyTyr: 2.15 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	2.088HisAla: 2.088 ± 0.021	0.333HisCys: 0.333 ± 0.008	1.498HisAsp: 1.498 ± 0.016	1.473HisGlu: 1.473 ± 0.019	0.965HisPhe: 0.965 ± 0.014	1.728HisGly: 1.728 ± 0.017	0.825HisHis: 0.825 ± 0.015	1.146HisIle: 1.146 ± 0.013	0.997HisLys: 0.997 ± 0.014	2.13HisLeu: 2.13 ± 0.022	0.493HisMet: 0.493 ± 0.009	0.892HisAsn: 0.892 ± 0.013	1.508HisPro: 1.508 ± 0.019	0.97HisGln: 0.97 ± 0.014	1.481HisArg: 1.481 ± 0.016	1.828HisSer: 1.828 ± 0.021	1.269HisThr: 1.269 ± 0.016	1.527HisVal: 1.527 ± 0.017	0.368HisTrp: 0.368 ± 0.009	0.707HisTyr: 0.707 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.374IleAla: 4.374 ± 0.03	0.713IleCys: 0.713 ± 0.012	2.916IleAsp: 2.916 ± 0.024	2.95IleGlu: 2.95 ± 0.024	1.839IlePhe: 1.839 ± 0.022	3.14IleGly: 3.14 ± 0.031	1.066IleHis: 1.066 ± 0.014	2.179IleIle: 2.179 ± 0.023	2.086IleLys: 2.086 ± 0.024	4.06IleLeu: 4.06 ± 0.029	0.986IleMet: 0.986 ± 0.013	1.712IleAsn: 1.712 ± 0.018	2.72IlePro: 2.72 ± 0.024	1.711IleGln: 1.711 ± 0.018	2.609IleArg: 2.609 ± 0.022	3.497IleSer: 3.497 ± 0.027	2.744IleThr: 2.744 ± 0.025	3.125IleVal: 3.125 ± 0.026	0.721IleTrp: 0.721 ± 0.013	1.319IleTyr: 1.319 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.619LysAla: 4.619 ± 0.039	0.484LysCys: 0.484 ± 0.012	2.954LysAsp: 2.954 ± 0.026	3.435LysGlu: 3.435 ± 0.033	1.419LysPhe: 1.419 ± 0.018	2.953LysGly: 2.953 ± 0.027	1.23LysHis: 1.23 ± 0.017	2.21LysIle: 2.21 ± 0.02	3.486LysLys: 3.486 ± 0.047	4.177LysLeu: 4.177 ± 0.028	1.027LysMet: 1.027 ± 0.015	1.721LysAsn: 1.721 ± 0.019	2.778LysPro: 2.778 ± 0.026	2.149LysGln: 2.149 ± 0.023	3.603LysArg: 3.603 ± 0.03	3.471LysSer: 3.471 ± 0.03	2.852LysThr: 2.852 ± 0.024	2.85LysVal: 2.85 ± 0.024	0.723LysTrp: 0.723 ± 0.01	1.377LysTyr: 1.377 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.976LeuAla: 7.976 ± 0.049	1.125LeuCys: 1.125 ± 0.015	5.065LeuAsp: 5.065 ± 0.037	5.412LeuGlu: 5.412 ± 0.036	3.022LeuPhe: 3.022 ± 0.028	5.638LeuGly: 5.638 ± 0.041	2.228LeuHis: 2.228 ± 0.021	3.648LeuIle: 3.648 ± 0.031	4.13LeuLys: 4.13 ± 0.034	7.861LeuLeu: 7.861 ± 0.059	1.694LeuMet: 1.694 ± 0.019	3.059LeuAsn: 3.059 ± 0.023	5.476LeuPro: 5.476 ± 0.033	4.043LeuGln: 4.043 ± 0.03	5.662LeuArg: 5.662 ± 0.038	6.625LeuSer: 6.625 ± 0.039	4.682LeuThr: 4.682 ± 0.032	5.072LeuVal: 5.072 ± 0.036	1.159LeuTrp: 1.159 ± 0.015	2.275LeuTyr: 2.275 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.278MetAla: 2.278 ± 0.019	0.244MetCys: 0.244 ± 0.007	1.193MetAsp: 1.193 ± 0.016	1.222MetGlu: 1.222 ± 0.014	0.725MetPhe: 0.725 ± 0.013	1.398MetGly: 1.398 ± 0.018	0.546MetHis: 0.546 ± 0.009	0.956MetIle: 0.956 ± 0.016	1.033MetLys: 1.033 ± 0.016	1.902MetLeu: 1.902 ± 0.018	0.557MetMet: 0.557 ± 0.011	0.788MetAsn: 0.788 ± 0.014	1.365MetPro: 1.365 ± 0.015	0.985MetGln: 0.985 ± 0.014	1.323MetArg: 1.323 ± 0.017	1.825MetSer: 1.825 ± 0.02	1.268MetThr: 1.268 ± 0.015	1.157MetVal: 1.157 ± 0.014	0.279MetTrp: 0.279 ± 0.007	0.537MetTyr: 0.537 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.524AsnAla: 3.524 ± 0.025	0.426AsnCys: 0.426 ± 0.009	2.126AsnAsp: 2.126 ± 0.021	2.154AsnGlu: 2.154 ± 0.019	1.397AsnPhe: 1.397 ± 0.017	3.349AsnGly: 3.349 ± 0.03	0.811AsnHis: 0.811 ± 0.013	1.912AsnIle: 1.912 ± 0.017	1.54AsnLys: 1.54 ± 0.018	3.029AsnLeu: 3.029 ± 0.024	0.828AsnMet: 0.828 ± 0.012	1.574AsnAsn: 1.574 ± 0.027	2.22AsnPro: 2.22 ± 0.025	1.29AsnGln: 1.29 ± 0.016	1.851AsnArg: 1.851 ± 0.021	2.667AsnSer: 2.667 ± 0.028	2.28AsnThr: 2.28 ± 0.023	2.425AsnVal: 2.425 ± 0.024	0.582AsnTrp: 0.582 ± 0.011	1.029AsnTyr: 1.029 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.656ProAla: 5.656 ± 0.044	0.47ProCys: 0.47 ± 0.01	3.087ProAsp: 3.087 ± 0.027	3.842ProGlu: 3.842 ± 0.026	1.93ProPhe: 1.93 ± 0.018	3.97ProGly: 3.97 ± 0.033	1.312ProHis: 1.312 ± 0.015	2.411ProIle: 2.411 ± 0.021	2.694ProLys: 2.694 ± 0.026	4.443ProLeu: 4.443 ± 0.031	1.035ProMet: 1.035 ± 0.014	2.211ProAsn: 2.211 ± 0.024	4.998ProPro: 4.998 ± 0.066	2.623ProGln: 2.623 ± 0.027	3.347ProArg: 3.347 ± 0.033	5.43ProSer: 5.43 ± 0.039	3.935ProThr: 3.935 ± 0.033	3.397ProVal: 3.397 ± 0.024	0.713ProTrp: 0.713 ± 0.013	1.513ProTyr: 1.513 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.945GlnAla: 3.945 ± 0.031	0.448GlnCys: 0.448 ± 0.01	2.327GlnAsp: 2.327 ± 0.022	2.609GlnGlu: 2.609 ± 0.027	1.265GlnPhe: 1.265 ± 0.014	2.443GlnGly: 2.443 ± 0.024	1.309GlnHis: 1.309 ± 0.017	1.945GlnIle: 1.945 ± 0.02	2.165GlnLys: 2.165 ± 0.021	3.637GlnLeu: 3.637 ± 0.029	0.928GlnMet: 0.928 ± 0.016	1.678GlnAsn: 1.678 ± 0.018	2.676GlnPro: 2.676 ± 0.03	3.094GlnGln: 3.094 ± 0.043	2.933GlnArg: 2.933 ± 0.027	3.253GlnSer: 3.253 ± 0.026	2.465GlnThr: 2.465 ± 0.02	2.235GlnVal: 2.235 ± 0.021	0.625GlnTrp: 0.625 ± 0.01	1.293GlnTyr: 1.293 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.009ArgAla: 5.009 ± 0.033	0.656ArgCys: 0.656 ± 0.011	3.502ArgAsp: 3.502 ± 0.032	3.922ArgGlu: 3.922 ± 0.033	2.027ArgPhe: 2.027 ± 0.019	3.697ArgGly: 3.697 ± 0.032	1.518ArgHis: 1.518 ± 0.019	2.803ArgIle: 2.803 ± 0.023	3.693ArgLys: 3.693 ± 0.034	5.181ArgLeu: 5.181 ± 0.032	1.366ArgMet: 1.366 ± 0.017	2.326ArgAsn: 2.326 ± 0.023	3.55ArgPro: 3.55 ± 0.034	2.826ArgGln: 2.826 ± 0.025	4.868ArgArg: 4.868 ± 0.044	4.75ArgSer: 4.75 ± 0.041	3.476ArgThr: 3.476 ± 0.028	3.271ArgVal: 3.271 ± 0.023	0.915ArgTrp: 0.915 ± 0.013	1.613ArgTyr: 1.613 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.968SerAla: 6.968 ± 0.044	0.788SerCys: 0.788 ± 0.012	4.192SerAsp: 4.192 ± 0.032	4.138SerGlu: 4.138 ± 0.029	2.723SerPhe: 2.723 ± 0.024	5.608SerGly: 5.608 ± 0.042	1.803SerHis: 1.803 ± 0.018	3.691SerIle: 3.691 ± 0.03	3.719SerLys: 3.719 ± 0.034	6.415SerLeu: 6.415 ± 0.038	1.694SerMet: 1.694 ± 0.017	2.987SerAsn: 2.987 ± 0.024	5.047SerPro: 5.047 ± 0.049	3.218SerGln: 3.218 ± 0.027	4.827SerArg: 4.827 ± 0.036	8.029SerSer: 8.029 ± 0.067	5.556SerThr: 5.556 ± 0.042	4.307SerVal: 4.307 ± 0.027	1.107SerTrp: 1.107 ± 0.015	2.006SerTyr: 2.006 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.679ThrAla: 5.679 ± 0.038	0.717ThrCys: 0.717 ± 0.012	2.881ThrAsp: 2.881 ± 0.021	3.193ThrGlu: 3.193 ± 0.023	2.293ThrPhe: 2.293 ± 0.02	4.268ThrGly: 4.268 ± 0.032	1.277ThrHis: 1.277 ± 0.017	3.113ThrIle: 3.113 ± 0.029	2.732ThrLys: 2.732 ± 0.025	5.058ThrLeu: 5.058 ± 0.036	1.225ThrMet: 1.225 ± 0.016	2.235ThrAsn: 2.235 ± 0.021	4.262ThrPro: 4.262 ± 0.032	2.235ThrGln: 2.235 ± 0.021	3.189ThrArg: 3.189 ± 0.024	5.394ThrSer: 5.394 ± 0.04	4.624ThrThr: 4.624 ± 0.065	3.577ThrVal: 3.577 ± 0.034	0.873ThrTrp: 0.873 ± 0.014	1.646ThrTyr: 1.646 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.457ValAla: 5.457 ± 0.037	0.781ValCys: 0.781 ± 0.012	3.648ValAsp: 3.648 ± 0.024	3.946ValGlu: 3.946 ± 0.031	2.282ValPhe: 2.282 ± 0.021	3.922ValGly: 3.922 ± 0.028	1.427ValHis: 1.427 ± 0.019	2.667ValIle: 2.667 ± 0.027	2.966ValLys: 2.966 ± 0.028	5.422ValLeu: 5.422 ± 0.038	1.242ValMet: 1.242 ± 0.014	2.219ValAsn: 2.219 ± 0.021	3.563ValPro: 3.563 ± 0.026	2.594ValGln: 2.594 ± 0.021	3.431ValArg: 3.431 ± 0.027	4.271ValSer: 4.271 ± 0.028	3.486ValThr: 3.486 ± 0.032	4.144ValVal: 4.144 ± 0.034	0.856ValTrp: 0.856 ± 0.014	1.647ValTyr: 1.647 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.14TrpAla: 1.14 ± 0.015	0.201TrpCys: 0.201 ± 0.006	0.87TrpAsp: 0.87 ± 0.013	0.816TrpGlu: 0.816 ± 0.012	0.548TrpPhe: 0.548 ± 0.01	0.844TrpGly: 0.844 ± 0.014	0.397TrpHis: 0.397 ± 0.008	0.759TrpIle: 0.759 ± 0.012	0.812TrpLys: 0.812 ± 0.012	1.381TrpLeu: 1.381 ± 0.016	0.359TrpMet: 0.359 ± 0.009	0.646TrpAsn: 0.646 ± 0.01	0.635TrpPro: 0.635 ± 0.012	0.694TrpGln: 0.694 ± 0.011	0.987TrpArg: 0.987 ± 0.013	1.084TrpSer: 1.084 ± 0.016	0.993TrpThr: 0.993 ± 0.015	0.795TrpVal: 0.795 ± 0.012	0.259TrpTrp: 0.259 ± 0.007	0.462TrpTyr: 0.462 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.336TyrAla: 2.336 ± 0.021	0.413TyrCys: 0.413 ± 0.008	1.748TyrAsp: 1.748 ± 0.021	1.629TyrGlu: 1.629 ± 0.018	1.125TyrPhe: 1.125 ± 0.016	2.195TyrGly: 2.195 ± 0.024	0.75TyrHis: 0.75 ± 0.011	1.285TyrIle: 1.285 ± 0.015	1.088TyrLys: 1.088 ± 0.015	2.48TyrLeu: 2.48 ± 0.021	0.614TyrMet: 0.614 ± 0.01	1.132TyrAsn: 1.132 ± 0.017	1.412TyrPro: 1.412 ± 0.017	1.168TyrGln: 1.168 ± 0.016	1.594TyrArg: 1.594 ± 0.017	1.95TyrSer: 1.95 ± 0.024	1.608TyrThr: 1.608 ± 0.017	1.631TyrVal: 1.631 ± 0.016	0.444TyrTrp: 0.444 ± 0.009	0.933TyrTyr: 0.933 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11903 proteins (5823408 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---