Amino acid dipepetide frequency for Xylona heveae (strain CBS 132557 / TC161)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.408AlaAla: 9.408 ± 0.081	0.945AlaCys: 0.945 ± 0.018	4.186AlaAsp: 4.186 ± 0.034	5.424AlaGlu: 5.424 ± 0.05	3.056AlaPhe: 3.056 ± 0.027	6.072AlaGly: 6.072 ± 0.051	1.849AlaHis: 1.849 ± 0.023	4.123AlaIle: 4.123 ± 0.04	4.115AlaLys: 4.115 ± 0.04	7.664AlaLeu: 7.664 ± 0.051	1.782AlaMet: 1.782 ± 0.022	2.943AlaAsn: 2.943 ± 0.032	5.052AlaPro: 5.052 ± 0.053	3.575AlaGln: 3.575 ± 0.036	5.054AlaArg: 5.054 ± 0.039	7.756AlaSer: 7.756 ± 0.056	5.094AlaThr: 5.094 ± 0.038	5.025AlaVal: 5.025 ± 0.042	1.045AlaTrp: 1.045 ± 0.018	2.04AlaTyr: 2.04 ± 0.028	0.0AlaXaa: 0.0 ± 0.0
Cys	0.852CysAla: 0.852 ± 0.017	0.244CysCys: 0.244 ± 0.01	0.574CysAsp: 0.574 ± 0.014	0.55CysGlu: 0.55 ± 0.014	0.531CysPhe: 0.531 ± 0.012	0.859CysGly: 0.859 ± 0.018	0.327CysHis: 0.327 ± 0.011	0.676CysIle: 0.676 ± 0.013	0.485CysLys: 0.485 ± 0.012	1.227CysLeu: 1.227 ± 0.021	0.245CysMet: 0.245 ± 0.009	0.424CysAsn: 0.424 ± 0.01	0.605CysPro: 0.605 ± 0.017	0.426CysGln: 0.426 ± 0.011	0.709CysArg: 0.709 ± 0.015	0.889CysSer: 0.889 ± 0.019	0.614CysThr: 0.614 ± 0.013	0.7CysVal: 0.7 ± 0.014	0.188CysTrp: 0.188 ± 0.007	0.341CysTyr: 0.341 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.657AspAla: 4.657 ± 0.035	0.572AspCys: 0.572 ± 0.013	4.204AspAsp: 4.204 ± 0.057	4.699AspGlu: 4.699 ± 0.049	2.149AspPhe: 2.149 ± 0.022	3.844AspGly: 3.844 ± 0.034	1.241AspHis: 1.241 ± 0.019	3.008AspIle: 3.008 ± 0.028	2.279AspLys: 2.279 ± 0.026	4.977AspLeu: 4.977 ± 0.035	1.132AspMet: 1.132 ± 0.016	1.853AspAsn: 1.853 ± 0.023	3.266AspPro: 3.266 ± 0.034	1.908AspGln: 1.908 ± 0.022	3.057AspArg: 3.057 ± 0.032	4.066AspSer: 4.066 ± 0.035	2.726AspThr: 2.726 ± 0.031	3.503AspVal: 3.503 ± 0.033	0.821AspTrp: 0.821 ± 0.014	1.534AspTyr: 1.534 ± 0.023	0.0AspXaa: 0.0 ± 0.0
Glu	5.423GluAla: 5.423 ± 0.047	0.556GluCys: 0.556 ± 0.011	4.425GluAsp: 4.425 ± 0.052	6.081GluGlu: 6.081 ± 0.075	1.928GluPhe: 1.928 ± 0.024	3.902GluGly: 3.902 ± 0.036	1.468GluHis: 1.468 ± 0.019	3.169GluIle: 3.169 ± 0.028	3.935GluLys: 3.935 ± 0.038	5.205GluLeu: 5.205 ± 0.04	1.435GluMet: 1.435 ± 0.02	2.531GluAsn: 2.531 ± 0.026	2.779GluPro: 2.779 ± 0.034	2.662GluGln: 2.662 ± 0.027	4.258GluArg: 4.258 ± 0.043	4.528GluSer: 4.528 ± 0.043	3.473GluThr: 3.473 ± 0.03	3.414GluVal: 3.414 ± 0.033	0.839GluTrp: 0.839 ± 0.016	1.636GluTyr: 1.636 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.05PheAla: 3.05 ± 0.031	0.582PheCys: 0.582 ± 0.013	2.271PheAsp: 2.271 ± 0.025	2.187PheGlu: 2.187 ± 0.025	1.754PhePhe: 1.754 ± 0.03	2.816PheGly: 2.816 ± 0.035	0.914PheHis: 0.914 ± 0.016	1.767PheIle: 1.767 ± 0.026	1.472PheLys: 1.472 ± 0.022	3.633PheLeu: 3.633 ± 0.036	0.722PheMet: 0.722 ± 0.013	1.383PheAsn: 1.383 ± 0.021	2.05PhePro: 2.05 ± 0.024	1.375PheGln: 1.375 ± 0.021	2.004PheArg: 2.004 ± 0.023	3.291PheSer: 3.291 ± 0.031	2.051PheThr: 2.051 ± 0.025	2.342PheVal: 2.342 ± 0.024	0.594PheTrp: 0.594 ± 0.012	1.105PheTyr: 1.105 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	5.448GlyAla: 5.448 ± 0.043	0.779GlyCys: 0.779 ± 0.015	3.501GlyAsp: 3.501 ± 0.033	3.799GlyGlu: 3.799 ± 0.034	2.763GlyPhe: 2.763 ± 0.03	5.839GlyGly: 5.839 ± 0.067	1.662GlyHis: 1.662 ± 0.024	3.446GlyIle: 3.446 ± 0.031	3.517GlyLys: 3.517 ± 0.039	5.977GlyLeu: 5.977 ± 0.046	1.464GlyMet: 1.464 ± 0.022	2.571GlyAsn: 2.571 ± 0.032	3.526GlyPro: 3.526 ± 0.042	2.603GlyGln: 2.603 ± 0.032	4.243GlyArg: 4.243 ± 0.036	6.003GlySer: 6.003 ± 0.05	3.924GlyThr: 3.924 ± 0.038	4.189GlyVal: 4.189 ± 0.038	1.078GlyTrp: 1.078 ± 0.016	1.994GlyTyr: 1.994 ± 0.027	0.0GlyXaa: 0.0 ± 0.0
His	1.907HisAla: 1.907 ± 0.023	0.314HisCys: 0.314 ± 0.01	1.313HisAsp: 1.313 ± 0.018	1.378HisGlu: 1.378 ± 0.019	0.956HisPhe: 0.956 ± 0.016	1.756HisGly: 1.756 ± 0.019	1.006HisHis: 1.006 ± 0.025	1.153HisIle: 1.153 ± 0.018	0.922HisLys: 0.922 ± 0.015	2.349HisLeu: 2.349 ± 0.024	0.454HisMet: 0.454 ± 0.012	0.847HisAsn: 0.847 ± 0.015	1.751HisPro: 1.751 ± 0.023	1.04HisGln: 1.04 ± 0.019	1.589HisArg: 1.589 ± 0.024	2.01HisSer: 2.01 ± 0.026	1.244HisThr: 1.244 ± 0.016	1.425HisVal: 1.425 ± 0.019	0.309HisTrp: 0.309 ± 0.008	0.688HisTyr: 0.688 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.012IleAla: 4.012 ± 0.038	0.749IleCys: 0.749 ± 0.015	2.833IleAsp: 2.833 ± 0.028	2.926IleGlu: 2.926 ± 0.029	2.031IlePhe: 2.031 ± 0.028	3.107IleGly: 3.107 ± 0.035	1.176IleHis: 1.176 ± 0.016	2.488IleIle: 2.488 ± 0.034	2.177IleLys: 2.177 ± 0.024	4.575IleLeu: 4.575 ± 0.041	0.962IleMet: 0.962 ± 0.016	1.788IleAsn: 1.788 ± 0.022	3.012IlePro: 3.012 ± 0.031	1.857IleGln: 1.857 ± 0.022	2.812IleArg: 2.812 ± 0.029	4.154IleSer: 4.154 ± 0.035	2.585IleThr: 2.585 ± 0.031	3.005IleVal: 3.005 ± 0.03	0.683IleTrp: 0.683 ± 0.012	1.433IleTyr: 1.433 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	4.238LysAla: 4.238 ± 0.039	0.48LysCys: 0.48 ± 0.013	2.792LysAsp: 2.792 ± 0.03	3.536LysGlu: 3.536 ± 0.037	1.494LysPhe: 1.494 ± 0.021	3.009LysGly: 3.009 ± 0.033	1.16LysHis: 1.16 ± 0.017	2.282LysIle: 2.282 ± 0.025	3.326LysLys: 3.326 ± 0.053	4.099LysLeu: 4.099 ± 0.034	0.98LysMet: 0.98 ± 0.015	1.738LysAsn: 1.738 ± 0.025	2.73LysPro: 2.73 ± 0.031	1.952LysGln: 1.952 ± 0.023	3.62LysArg: 3.62 ± 0.037	3.757LysSer: 3.757 ± 0.035	2.646LysThr: 2.646 ± 0.026	2.764LysVal: 2.764 ± 0.028	0.647LysTrp: 0.647 ± 0.013	1.353LysTyr: 1.353 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	7.657LeuAla: 7.657 ± 0.055	1.172LeuCys: 1.172 ± 0.02	5.118LeuAsp: 5.118 ± 0.041	5.606LeuGlu: 5.606 ± 0.04	3.528LeuPhe: 3.528 ± 0.037	5.829LeuGly: 5.829 ± 0.04	2.255LeuHis: 2.255 ± 0.026	3.883LeuIle: 3.883 ± 0.036	4.241LeuLys: 4.241 ± 0.034	8.442LeuLeu: 8.442 ± 0.069	1.642LeuMet: 1.642 ± 0.021	3.174LeuAsn: 3.174 ± 0.032	5.599LeuPro: 5.599 ± 0.043	3.861LeuGln: 3.861 ± 0.035	5.995LeuArg: 5.995 ± 0.046	7.914LeuSer: 7.914 ± 0.046	4.588LeuThr: 4.588 ± 0.041	5.191LeuVal: 5.191 ± 0.043	1.094LeuTrp: 1.094 ± 0.02	2.291LeuTyr: 2.291 ± 0.028	0.0LeuXaa: 0.0 ± 0.0
Met	2.003MetAla: 2.003 ± 0.022	0.215MetCys: 0.215 ± 0.007	1.182MetAsp: 1.182 ± 0.019	1.197MetGlu: 1.197 ± 0.018	0.688MetPhe: 0.688 ± 0.012	1.329MetGly: 1.329 ± 0.02	0.46MetHis: 0.46 ± 0.013	0.93MetIle: 0.93 ± 0.015	0.903MetLys: 0.903 ± 0.016	1.753MetLeu: 1.753 ± 0.024	0.49MetMet: 0.49 ± 0.012	0.754MetAsn: 0.754 ± 0.014	1.19MetPro: 1.19 ± 0.021	0.84MetGln: 0.84 ± 0.016	1.223MetArg: 1.223 ± 0.017	1.793MetSer: 1.793 ± 0.02	1.222MetThr: 1.222 ± 0.016	1.168MetVal: 1.168 ± 0.019	0.227MetTrp: 0.227 ± 0.007	0.46MetTyr: 0.46 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.211AsnAla: 3.211 ± 0.033	0.424AsnCys: 0.424 ± 0.012	2.05AsnAsp: 2.05 ± 0.026	2.193AsnGlu: 2.193 ± 0.027	1.389AsnPhe: 1.389 ± 0.022	2.991AsnGly: 2.991 ± 0.034	0.866AsnHis: 0.866 ± 0.016	2.018AsnIle: 2.018 ± 0.025	1.602AsnLys: 1.602 ± 0.021	3.333AsnLeu: 3.333 ± 0.031	0.724AsnMet: 0.724 ± 0.014	1.562AsnAsn: 1.562 ± 0.023	2.483AsnPro: 2.483 ± 0.028	1.332AsnGln: 1.332 ± 0.017	1.967AsnArg: 1.967 ± 0.021	2.8AsnSer: 2.8 ± 0.033	2.084AsnThr: 2.084 ± 0.029	2.355AsnVal: 2.355 ± 0.025	0.521AsnTrp: 0.521 ± 0.011	1.028AsnTyr: 1.028 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.462ProAla: 5.462 ± 0.053	0.488ProCys: 0.488 ± 0.012	2.978ProAsp: 2.978 ± 0.026	3.892ProGlu: 3.892 ± 0.036	2.203ProPhe: 2.203 ± 0.025	3.968ProGly: 3.968 ± 0.042	1.432ProHis: 1.432 ± 0.023	2.514ProIle: 2.514 ± 0.028	2.698ProLys: 2.698 ± 0.028	4.961ProLeu: 4.961 ± 0.043	1.029ProMet: 1.029 ± 0.016	2.198ProAsn: 2.198 ± 0.025	5.564ProPro: 5.564 ± 0.095	2.6ProGln: 2.6 ± 0.038	3.622ProArg: 3.622 ± 0.036	6.776ProSer: 6.776 ± 0.062	3.91ProThr: 3.91 ± 0.039	3.539ProVal: 3.539 ± 0.037	0.668ProTrp: 0.668 ± 0.014	1.494ProTyr: 1.494 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.536GlnAla: 3.536 ± 0.038	0.429GlnCys: 0.429 ± 0.011	2.001GlnAsp: 2.001 ± 0.021	2.483GlnGlu: 2.483 ± 0.028	1.262GlnPhe: 1.262 ± 0.017	2.456GlnGly: 2.456 ± 0.027	1.125GlnHis: 1.125 ± 0.018	1.953GlnIle: 1.953 ± 0.022	2.112GlnLys: 2.112 ± 0.025	3.48GlnLeu: 3.48 ± 0.033	0.869GlnMet: 0.869 ± 0.016	1.637GlnAsn: 1.637 ± 0.019	2.661GlnPro: 2.661 ± 0.039	2.602GlnGln: 2.602 ± 0.061	2.865GlnArg: 2.865 ± 0.029	3.437GlnSer: 3.437 ± 0.038	2.351GlnThr: 2.351 ± 0.02	2.031GlnVal: 2.031 ± 0.022	0.515GlnTrp: 0.515 ± 0.01	1.089GlnTyr: 1.089 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.856ArgAla: 4.856 ± 0.039	0.683ArgCys: 0.683 ± 0.015	3.337ArgAsp: 3.337 ± 0.036	4.08ArgGlu: 4.08 ± 0.042	2.161ArgPhe: 2.161 ± 0.027	3.936ArgGly: 3.936 ± 0.041	1.649ArgHis: 1.649 ± 0.022	2.959ArgIle: 2.959 ± 0.032	3.686ArgLys: 3.686 ± 0.038	5.58ArgLeu: 5.58 ± 0.038	1.292ArgMet: 1.292 ± 0.02	2.376ArgAsn: 2.376 ± 0.024	3.737ArgPro: 3.737 ± 0.038	2.792ArgGln: 2.792 ± 0.03	5.623ArgArg: 5.623 ± 0.058	5.207ArgSer: 5.207 ± 0.055	3.309ArgThr: 3.309 ± 0.029	3.347ArgVal: 3.347 ± 0.032	0.877ArgTrp: 0.877 ± 0.015	1.62ArgTyr: 1.62 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	7.426SerAla: 7.426 ± 0.054	0.857SerCys: 0.857 ± 0.016	4.197SerAsp: 4.197 ± 0.037	4.48SerGlu: 4.48 ± 0.039	3.28SerPhe: 3.28 ± 0.031	5.875SerGly: 5.875 ± 0.045	2.112SerHis: 2.112 ± 0.025	4.164SerIle: 4.164 ± 0.035	4.026SerLys: 4.026 ± 0.04	7.619SerLeu: 7.619 ± 0.049	1.672SerMet: 1.672 ± 0.023	3.295SerAsn: 3.295 ± 0.032	6.096SerPro: 6.096 ± 0.069	3.545SerGln: 3.545 ± 0.038	5.458SerArg: 5.458 ± 0.05	11.198SerSer: 11.198 ± 0.123	5.911SerThr: 5.911 ± 0.053	4.596SerVal: 4.596 ± 0.038	1.012SerTrp: 1.012 ± 0.016	2.083SerTyr: 2.083 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	5.08ThrAla: 5.08 ± 0.039	0.685ThrCys: 0.685 ± 0.014	2.656ThrAsp: 2.656 ± 0.023	3.053ThrGlu: 3.053 ± 0.028	2.164ThrPhe: 2.164 ± 0.024	4.11ThrGly: 4.11 ± 0.043	1.26ThrHis: 1.26 ± 0.017	2.873ThrIle: 2.873 ± 0.026	2.494ThrLys: 2.494 ± 0.028	5.073ThrLeu: 5.073 ± 0.039	1.09ThrMet: 1.09 ± 0.018	2.082ThrAsn: 2.082 ± 0.026	4.316ThrPro: 4.316 ± 0.046	2.022ThrGln: 2.022 ± 0.021	3.103ThrArg: 3.103 ± 0.028	5.567ThrSer: 5.567 ± 0.057	4.063ThrThr: 4.063 ± 0.052	3.433ThrVal: 3.433 ± 0.032	0.719ThrTrp: 0.719 ± 0.015	1.443ThrTyr: 1.443 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	4.905ValAla: 4.905 ± 0.039	0.731ValCys: 0.731 ± 0.016	3.501ValAsp: 3.501 ± 0.028	3.78ValGlu: 3.78 ± 0.036	2.341ValPhe: 2.341 ± 0.029	3.835ValGly: 3.835 ± 0.04	1.383ValHis: 1.383 ± 0.018	2.881ValIle: 2.881 ± 0.029	2.793ValLys: 2.793 ± 0.031	5.29ValLeu: 5.29 ± 0.044	1.165ValMet: 1.165 ± 0.018	2.139ValAsn: 2.139 ± 0.021	3.583ValPro: 3.583 ± 0.032	2.311ValGln: 2.311 ± 0.025	3.402ValArg: 3.402 ± 0.03	4.715ValSer: 4.715 ± 0.033	3.208ValThr: 3.208 ± 0.032	3.837ValVal: 3.837 ± 0.038	0.759ValTrp: 0.759 ± 0.014	1.587ValTyr: 1.587 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.01TrpAla: 1.01 ± 0.019	0.176TrpCys: 0.176 ± 0.006	0.826TrpAsp: 0.826 ± 0.016	0.802TrpGlu: 0.802 ± 0.016	0.49TrpPhe: 0.49 ± 0.011	0.847TrpGly: 0.847 ± 0.016	0.322TrpHis: 0.322 ± 0.009	0.712TrpIle: 0.712 ± 0.014	0.762TrpLys: 0.762 ± 0.015	1.232TrpLeu: 1.232 ± 0.021	0.324TrpMet: 0.324 ± 0.008	0.571TrpAsn: 0.571 ± 0.012	0.541TrpPro: 0.541 ± 0.012	0.518TrpGln: 0.518 ± 0.011	0.942TrpArg: 0.942 ± 0.017	0.983TrpSer: 0.983 ± 0.015	0.815TrpThr: 0.815 ± 0.015	0.744TrpVal: 0.744 ± 0.014	0.26TrpTrp: 0.26 ± 0.01	0.373TrpTyr: 0.373 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.069TyrAla: 2.069 ± 0.024	0.387TyrCys: 0.387 ± 0.011	1.551TyrAsp: 1.551 ± 0.017	1.501TyrGlu: 1.501 ± 0.019	1.195TyrPhe: 1.195 ± 0.018	1.945TyrGly: 1.945 ± 0.029	0.745TyrHis: 0.745 ± 0.015	1.365TyrIle: 1.365 ± 0.019	1.062TyrLys: 1.062 ± 0.017	2.613TyrLeu: 2.613 ± 0.028	0.553TyrMet: 0.553 ± 0.012	1.064TyrAsn: 1.064 ± 0.017	1.451TyrPro: 1.451 ± 0.02	1.072TyrGln: 1.072 ± 0.019	1.561TyrArg: 1.561 ± 0.023	2.061TyrSer: 2.061 ± 0.024	1.467TyrThr: 1.467 ± 0.022	1.536TyrVal: 1.536 ± 0.021	0.394TyrTrp: 0.394 ± 0.011	0.907TyrTyr: 0.907 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8201 proteins (4004401 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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