Amino acid dipepetide frequency for Azospira oryzae (strain ATCC BAA-33 / DSM 13638 / PS) (Dechlorosoma suillum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.893AlaAla: 17.893 ± 0.198	1.281AlaCys: 1.281 ± 0.04	6.428AlaAsp: 6.428 ± 0.076	7.968AlaGlu: 7.968 ± 0.098	3.807AlaPhe: 3.807 ± 0.065	10.482AlaGly: 10.482 ± 0.118	2.333AlaHis: 2.333 ± 0.047	5.227AlaIle: 5.227 ± 0.078	4.447AlaLys: 4.447 ± 0.1	14.308AlaLeu: 14.308 ± 0.156	3.132AlaMet: 3.132 ± 0.05	3.013AlaAsn: 3.013 ± 0.06	5.819AlaPro: 5.819 ± 0.085	4.75AlaGln: 4.75 ± 0.083	8.348AlaArg: 8.348 ± 0.11	5.683AlaSer: 5.683 ± 0.084	5.266AlaThr: 5.266 ± 0.084	8.53AlaVal: 8.53 ± 0.101	1.726AlaTrp: 1.726 ± 0.052	2.65AlaTyr: 2.65 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	1.046CysAla: 1.046 ± 0.032	0.154CysCys: 0.154 ± 0.011	0.525CysAsp: 0.525 ± 0.024	0.416CysGlu: 0.416 ± 0.02	0.33CysPhe: 0.33 ± 0.019	1.025CysGly: 1.025 ± 0.036	0.356CysHis: 0.356 ± 0.02	0.442CysIle: 0.442 ± 0.022	0.272CysLys: 0.272 ± 0.019	1.063CysLeu: 1.063 ± 0.032	0.176CysMet: 0.176 ± 0.014	0.286CysAsn: 0.286 ± 0.017	0.626CysPro: 0.626 ± 0.026	0.352CysGln: 0.352 ± 0.02	0.738CysArg: 0.738 ± 0.029	0.518CysSer: 0.518 ± 0.024	0.445CysThr: 0.445 ± 0.018	0.574CysVal: 0.574 ± 0.024	0.12CysTrp: 0.12 ± 0.009	0.238CysTyr: 0.238 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	5.595AspAla: 5.595 ± 0.073	0.507AspCys: 0.507 ± 0.024	2.615AspAsp: 2.615 ± 0.053	3.228AspGlu: 3.228 ± 0.054	2.348AspPhe: 2.348 ± 0.052	4.684AspGly: 4.684 ± 0.072	1.02AspHis: 1.02 ± 0.031	2.626AspIle: 2.626 ± 0.049	1.994AspLys: 1.994 ± 0.045	5.797AspLeu: 5.797 ± 0.075	1.146AspMet: 1.146 ± 0.034	1.413AspAsn: 1.413 ± 0.041	2.754AspPro: 2.754 ± 0.052	1.807AspGln: 1.807 ± 0.043	3.025AspArg: 3.025 ± 0.057	2.542AspSer: 2.542 ± 0.048	2.418AspThr: 2.418 ± 0.059	3.374AspVal: 3.374 ± 0.057	0.884AspTrp: 0.884 ± 0.029	1.543AspTyr: 1.543 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	8.095GluAla: 8.095 ± 0.114	0.455GluCys: 0.455 ± 0.021	2.569GluAsp: 2.569 ± 0.05	3.823GluGlu: 3.823 ± 0.08	1.996GluPhe: 1.996 ± 0.041	4.264GluGly: 4.264 ± 0.065	1.339GluHis: 1.339 ± 0.039	3.137GluIle: 3.137 ± 0.063	2.865GluLys: 2.865 ± 0.055	6.478GluLeu: 6.478 ± 0.096	1.559GluMet: 1.559 ± 0.037	1.717GluAsn: 1.717 ± 0.039	2.408GluPro: 2.408 ± 0.052	2.936GluGln: 2.936 ± 0.063	4.951GluArg: 4.951 ± 0.079	2.933GluSer: 2.933 ± 0.051	2.946GluThr: 2.946 ± 0.054	4.612GluVal: 4.612 ± 0.077	0.847GluTrp: 0.847 ± 0.027	1.246GluTyr: 1.246 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.211PheAla: 4.211 ± 0.063	0.417PheCys: 0.417 ± 0.019	2.282PheAsp: 2.282 ± 0.048	1.925PheGlu: 1.925 ± 0.048	1.481PhePhe: 1.481 ± 0.046	3.02PheGly: 3.02 ± 0.059	0.845PheHis: 0.845 ± 0.028	1.628PheIle: 1.628 ± 0.034	1.233PheLys: 1.233 ± 0.034	3.578PheLeu: 3.578 ± 0.058	0.727PheMet: 0.727 ± 0.024	1.197PheAsn: 1.197 ± 0.031	1.639PhePro: 1.639 ± 0.037	1.179PheGln: 1.179 ± 0.031	2.069PheArg: 2.069 ± 0.041	2.269PheSer: 2.269 ± 0.051	1.743PheThr: 1.743 ± 0.044	2.529PheVal: 2.529 ± 0.056	0.506PheTrp: 0.506 ± 0.023	0.951PheTyr: 0.951 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	8.344GlyAla: 8.344 ± 0.109	1.013GlyCys: 1.013 ± 0.034	4.135GlyAsp: 4.135 ± 0.065	5.228GlyGlu: 5.228 ± 0.072	3.139GlyPhe: 3.139 ± 0.06	6.949GlyGly: 6.949 ± 0.114	1.961GlyHis: 1.961 ± 0.047	4.271GlyIle: 4.271 ± 0.068	3.939GlyLys: 3.939 ± 0.067	9.162GlyLeu: 9.162 ± 0.103	2.167GlyMet: 2.167 ± 0.047	2.43GlyAsn: 2.43 ± 0.082	2.82GlyPro: 2.82 ± 0.049	3.404GlyGln: 3.404 ± 0.064	5.56GlyArg: 5.56 ± 0.067	4.464GlySer: 4.464 ± 0.081	3.847GlyThr: 3.847 ± 0.086	5.868GlyVal: 5.868 ± 0.081	1.261GlyTrp: 1.261 ± 0.04	2.332GlyTyr: 2.332 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.258HisAla: 2.258 ± 0.047	0.308HisCys: 0.308 ± 0.017	1.093HisAsp: 1.093 ± 0.033	1.138HisGlu: 1.138 ± 0.032	0.976HisPhe: 0.976 ± 0.031	2.022HisGly: 2.022 ± 0.049	0.665HisHis: 0.665 ± 0.028	0.982HisIle: 0.982 ± 0.03	0.654HisLys: 0.654 ± 0.023	2.636HisLeu: 2.636 ± 0.049	0.436HisMet: 0.436 ± 0.019	0.583HisAsn: 0.583 ± 0.022	1.526HisPro: 1.526 ± 0.042	0.834HisGln: 0.834 ± 0.028	1.444HisArg: 1.444 ± 0.039	1.081HisSer: 1.081 ± 0.034	0.968HisThr: 0.968 ± 0.028	1.289HisVal: 1.289 ± 0.032	0.354HisTrp: 0.354 ± 0.019	0.656HisTyr: 0.656 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.712IleAla: 5.712 ± 0.075	0.402IleCys: 0.402 ± 0.017	2.706IleAsp: 2.706 ± 0.05	2.915IleGlu: 2.915 ± 0.054	1.456IlePhe: 1.456 ± 0.04	4.084IleGly: 4.084 ± 0.066	0.982IleHis: 0.982 ± 0.031	1.844IleIle: 1.844 ± 0.046	1.726IleLys: 1.726 ± 0.043	4.279IleLeu: 4.279 ± 0.068	0.778IleMet: 0.778 ± 0.027	1.561IleAsn: 1.561 ± 0.035	2.299IlePro: 2.299 ± 0.044	1.499IleGln: 1.499 ± 0.039	2.895IleArg: 2.895 ± 0.054	2.666IleSer: 2.666 ± 0.051	2.384IleThr: 2.384 ± 0.051	3.306IleVal: 3.306 ± 0.062	0.423IleTrp: 0.423 ± 0.02	1.082IleTyr: 1.082 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	4.557LysAla: 4.557 ± 0.086	0.206LysCys: 0.206 ± 0.015	1.918LysAsp: 1.918 ± 0.06	2.319LysGlu: 2.319 ± 0.061	1.053LysPhe: 1.053 ± 0.034	2.858LysGly: 2.858 ± 0.059	0.771LysHis: 0.771 ± 0.028	1.738LysIle: 1.738 ± 0.042	1.849LysLys: 1.849 ± 0.056	3.836LysLeu: 3.836 ± 0.059	0.91LysMet: 0.91 ± 0.034	1.123LysAsn: 1.123 ± 0.032	2.254LysPro: 2.254 ± 0.061	1.478LysGln: 1.478 ± 0.041	2.3LysArg: 2.3 ± 0.042	1.885LysSer: 1.885 ± 0.048	1.95LysThr: 1.95 ± 0.047	2.969LysVal: 2.969 ± 0.058	0.375LysTrp: 0.375 ± 0.018	0.791LysTyr: 0.791 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	16.195LeuAla: 16.195 ± 0.166	1.074LeuCys: 1.074 ± 0.033	5.843LeuAsp: 5.843 ± 0.081	7.03LeuGlu: 7.03 ± 0.097	3.838LeuPhe: 3.838 ± 0.062	9.069LeuGly: 9.069 ± 0.098	2.344LeuHis: 2.344 ± 0.045	4.475LeuIle: 4.475 ± 0.061	4.308LeuLys: 4.308 ± 0.069	13.313LeuLeu: 13.313 ± 0.165	2.279LeuMet: 2.279 ± 0.049	3.007LeuAsn: 3.007 ± 0.061	6.595LeuPro: 6.595 ± 0.088	4.563LeuGln: 4.563 ± 0.078	7.165LeuArg: 7.165 ± 0.087	6.334LeuSer: 6.334 ± 0.081	5.575LeuThr: 5.575 ± 0.092	7.754LeuVal: 7.754 ± 0.103	1.361LeuTrp: 1.361 ± 0.043	2.255LeuTyr: 2.255 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	2.903MetAla: 2.903 ± 0.059	0.129MetCys: 0.129 ± 0.011	1.139MetAsp: 1.139 ± 0.03	1.322MetGlu: 1.322 ± 0.031	0.633MetPhe: 0.633 ± 0.024	1.763MetGly: 1.763 ± 0.043	0.467MetHis: 0.467 ± 0.018	0.881MetIle: 0.881 ± 0.029	1.011MetLys: 1.011 ± 0.031	2.302MetLeu: 2.302 ± 0.049	0.508MetMet: 0.508 ± 0.024	0.788MetAsn: 0.788 ± 0.027	1.361MetPro: 1.361 ± 0.037	0.908MetGln: 0.908 ± 0.026	1.356MetArg: 1.356 ± 0.036	1.515MetSer: 1.515 ± 0.033	1.281MetThr: 1.281 ± 0.038	1.589MetVal: 1.589 ± 0.038	0.177MetTrp: 0.177 ± 0.013	0.334MetTyr: 0.334 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.103AsnAla: 3.103 ± 0.065	0.3AsnCys: 0.3 ± 0.016	1.401AsnAsp: 1.401 ± 0.051	1.373AsnGlu: 1.373 ± 0.035	0.959AsnPhe: 0.959 ± 0.031	2.39AsnGly: 2.39 ± 0.051	0.557AsnHis: 0.557 ± 0.024	1.314AsnIle: 1.314 ± 0.036	0.918AsnLys: 0.918 ± 0.031	3.334AsnLeu: 3.334 ± 0.063	0.567AsnMet: 0.567 ± 0.023	0.829AsnAsn: 0.829 ± 0.028	1.986AsnPro: 1.986 ± 0.039	1.071AsnGln: 1.071 ± 0.029	1.987AsnArg: 1.987 ± 0.048	1.313AsnSer: 1.313 ± 0.041	1.363AsnThr: 1.363 ± 0.046	1.886AsnVal: 1.886 ± 0.043	0.364AsnTrp: 0.364 ± 0.02	0.739AsnTyr: 0.739 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	7.058ProAla: 7.058 ± 0.099	0.396ProCys: 0.396 ± 0.018	2.928ProAsp: 2.928 ± 0.053	4.022ProGlu: 4.022 ± 0.066	1.769ProPhe: 1.769 ± 0.042	4.545ProGly: 4.545 ± 0.076	1.075ProHis: 1.075 ± 0.032	1.951ProIle: 1.951 ± 0.044	1.644ProLys: 1.644 ± 0.045	5.69ProLeu: 5.69 ± 0.087	1.116ProMet: 1.116 ± 0.034	1.248ProAsn: 1.248 ± 0.031	2.748ProPro: 2.748 ± 0.066	1.957ProGln: 1.957 ± 0.041	3.071ProArg: 3.071 ± 0.068	2.374ProSer: 2.374 ± 0.051	2.215ProThr: 2.215 ± 0.049	4.085ProVal: 4.085 ± 0.064	0.767ProTrp: 0.767 ± 0.032	1.19ProTyr: 1.19 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	5.709GlnAla: 5.709 ± 0.086	0.293GlnCys: 0.293 ± 0.019	1.75GlnAsp: 1.75 ± 0.039	2.403GlnGlu: 2.403 ± 0.055	1.205GlnPhe: 1.205 ± 0.03	3.254GlnGly: 3.254 ± 0.057	0.876GlnHis: 0.876 ± 0.03	1.745GlnIle: 1.745 ± 0.048	1.38GlnLys: 1.38 ± 0.038	4.305GlnLeu: 4.305 ± 0.066	0.963GlnMet: 0.963 ± 0.031	0.962GlnAsn: 0.962 ± 0.031	2.174GlnPro: 2.174 ± 0.044	2.058GlnGln: 2.058 ± 0.046	3.203GlnArg: 3.203 ± 0.066	2.021GlnSer: 2.021 ± 0.048	1.769GlnThr: 1.769 ± 0.042	3.276GlnVal: 3.276 ± 0.07	0.552GlnTrp: 0.552 ± 0.025	0.776GlnTyr: 0.776 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	6.328ArgAla: 6.328 ± 0.092	0.655ArgCys: 0.655 ± 0.028	3.451ArgAsp: 3.451 ± 0.055	4.587ArgGlu: 4.587 ± 0.067	2.777ArgPhe: 2.777 ± 0.054	4.288ArgGly: 4.288 ± 0.067	1.991ArgHis: 1.991 ± 0.045	3.542ArgIle: 3.542 ± 0.056	2.131ArgLys: 2.131 ± 0.048	8.895ArgLeu: 8.895 ± 0.097	1.484ArgMet: 1.484 ± 0.038	1.969ArgAsn: 1.969 ± 0.047	3.238ArgPro: 3.238 ± 0.063	3.872ArgGln: 3.872 ± 0.074	5.323ArgArg: 5.323 ± 0.082	3.308ArgSer: 3.308 ± 0.058	2.639ArgThr: 2.639 ± 0.048	4.431ArgVal: 4.431 ± 0.065	0.996ArgTrp: 0.996 ± 0.029	1.897ArgTyr: 1.897 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.71SerAla: 5.71 ± 0.088	0.52SerCys: 0.52 ± 0.021	2.499SerAsp: 2.499 ± 0.047	2.656SerGlu: 2.656 ± 0.054	1.911SerPhe: 1.911 ± 0.049	5.097SerGly: 5.097 ± 0.085	1.229SerHis: 1.229 ± 0.033	2.441SerIle: 2.441 ± 0.047	1.608SerLys: 1.608 ± 0.043	6.529SerLeu: 6.529 ± 0.09	1.133SerMet: 1.133 ± 0.038	1.38SerAsn: 1.38 ± 0.039	2.84SerPro: 2.84 ± 0.05	1.947SerGln: 1.947 ± 0.047	3.906SerArg: 3.906 ± 0.067	2.938SerSer: 2.938 ± 0.066	2.411SerThr: 2.411 ± 0.06	3.599SerVal: 3.599 ± 0.063	0.668SerTrp: 0.668 ± 0.025	1.209SerTyr: 1.209 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	5.498ThrAla: 5.498 ± 0.084	0.438ThrCys: 0.438 ± 0.02	2.254ThrAsp: 2.254 ± 0.049	2.29ThrGlu: 2.29 ± 0.048	1.691ThrPhe: 1.691 ± 0.038	4.083ThrGly: 4.083 ± 0.093	0.949ThrHis: 0.949 ± 0.029	2.001ThrIle: 2.001 ± 0.043	1.33ThrLys: 1.33 ± 0.038	6.117ThrLeu: 6.117 ± 0.093	0.899ThrMet: 0.899 ± 0.034	1.159ThrAsn: 1.159 ± 0.034	3.314ThrPro: 3.314 ± 0.05	1.743ThrGln: 1.743 ± 0.037	2.962ThrArg: 2.962 ± 0.05	2.272ThrSer: 2.272 ± 0.063	2.376ThrThr: 2.376 ± 0.08	3.883ThrVal: 3.883 ± 0.079	0.59ThrTrp: 0.59 ± 0.022	1.131ThrTyr: 1.131 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	9.301ValAla: 9.301 ± 0.098	0.737ValCys: 0.737 ± 0.025	3.889ValAsp: 3.889 ± 0.06	4.644ValGlu: 4.644 ± 0.068	2.583ValPhe: 2.583 ± 0.047	5.452ValGly: 5.452 ± 0.081	1.333ValHis: 1.333 ± 0.035	3.31ValIle: 3.31 ± 0.058	2.576ValLys: 2.576 ± 0.057	7.962ValLeu: 7.962 ± 0.101	1.671ValMet: 1.671 ± 0.043	2.015ValAsn: 2.015 ± 0.044	3.571ValPro: 3.571 ± 0.056	2.483ValGln: 2.483 ± 0.047	4.486ValArg: 4.486 ± 0.05	4.15ValSer: 4.15 ± 0.059	3.754ValThr: 3.754 ± 0.063	5.969ValVal: 5.969 ± 0.083	0.842ValTrp: 0.842 ± 0.029	1.408ValTyr: 1.408 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.117TrpAla: 1.117 ± 0.036	0.148TrpCys: 0.148 ± 0.011	0.594TrpAsp: 0.594 ± 0.025	0.698TrpGlu: 0.698 ± 0.027	0.506TrpPhe: 0.506 ± 0.02	0.926TrpGly: 0.926 ± 0.032	0.318TrpHis: 0.318 ± 0.019	0.594TrpIle: 0.594 ± 0.025	0.471TrpLys: 0.471 ± 0.022	2.166TrpLeu: 2.166 ± 0.052	0.299TrpMet: 0.299 ± 0.016	0.407TrpAsn: 0.407 ± 0.021	0.589TrpPro: 0.589 ± 0.024	0.844TrpGln: 0.844 ± 0.033	1.115TrpArg: 1.115 ± 0.037	0.679TrpSer: 0.679 ± 0.023	0.494TrpThr: 0.494 ± 0.021	0.965TrpVal: 0.965 ± 0.034	0.241TrpTrp: 0.241 ± 0.015	0.259TrpTyr: 0.259 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.461TyrAla: 2.461 ± 0.047	0.271TyrCys: 0.271 ± 0.015	1.3TyrAsp: 1.3 ± 0.037	1.19TyrGlu: 1.19 ± 0.033	0.966TyrPhe: 0.966 ± 0.033	2.042TyrGly: 2.042 ± 0.046	0.492TyrHis: 0.492 ± 0.019	0.85TyrIle: 0.85 ± 0.028	0.784TyrLys: 0.784 ± 0.029	2.631TyrLeu: 2.631 ± 0.053	0.416TyrMet: 0.416 ± 0.02	0.669TyrAsn: 0.669 ± 0.025	1.288TyrPro: 1.288 ± 0.036	0.987TyrGln: 0.987 ± 0.029	1.899TyrArg: 1.899 ± 0.043	1.284TyrSer: 1.284 ± 0.037	1.136TyrThr: 1.136 ± 0.046	1.649TyrVal: 1.649 ± 0.045	0.373TyrTrp: 0.373 ± 0.018	0.666TyrTyr: 0.666 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3432 proteins (1138217 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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