Amino acid dipepetide frequency for Polytolypa hystricis UAMH7299

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.855AlaAla: 8.855 ± 0.064	0.986AlaCys: 0.986 ± 0.016	4.182AlaAsp: 4.182 ± 0.036	5.126AlaGlu: 5.126 ± 0.04	2.9AlaPhe: 2.9 ± 0.031	5.645AlaGly: 5.645 ± 0.045	1.726AlaHis: 1.726 ± 0.021	4.132AlaIle: 4.132 ± 0.036	4.03AlaLys: 4.03 ± 0.036	7.471AlaLeu: 7.471 ± 0.048	1.797AlaMet: 1.797 ± 0.022	2.925AlaAsn: 2.925 ± 0.029	4.694AlaPro: 4.694 ± 0.048	3.233AlaGln: 3.233 ± 0.026	4.852AlaArg: 4.852 ± 0.032	7.12AlaSer: 7.12 ± 0.042	5.128AlaThr: 5.128 ± 0.038	5.216AlaVal: 5.216 ± 0.04	1.047AlaTrp: 1.047 ± 0.017	2.055AlaTyr: 2.055 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.915CysAla: 0.915 ± 0.015	0.247CysCys: 0.247 ± 0.008	0.653CysAsp: 0.653 ± 0.013	0.624CysGlu: 0.624 ± 0.012	0.508CysPhe: 0.508 ± 0.012	0.912CysGly: 0.912 ± 0.016	0.313CysHis: 0.313 ± 0.009	0.661CysIle: 0.661 ± 0.013	0.524CysLys: 0.524 ± 0.011	1.254CysLeu: 1.254 ± 0.018	0.25CysMet: 0.25 ± 0.008	0.424CysAsn: 0.424 ± 0.012	0.686CysPro: 0.686 ± 0.014	0.436CysGln: 0.436 ± 0.01	0.749CysArg: 0.749 ± 0.014	0.899CysSer: 0.899 ± 0.016	0.64CysThr: 0.64 ± 0.012	0.759CysVal: 0.759 ± 0.014	0.19CysTrp: 0.19 ± 0.007	0.342CysTyr: 0.342 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.537AspAla: 4.537 ± 0.035	0.617AspCys: 0.617 ± 0.013	4.406AspAsp: 4.406 ± 0.046	4.541AspGlu: 4.541 ± 0.042	2.14AspPhe: 2.14 ± 0.022	4.108AspGly: 4.108 ± 0.034	1.223AspHis: 1.223 ± 0.018	3.348AspIle: 3.348 ± 0.026	2.418AspLys: 2.418 ± 0.026	4.96AspLeu: 4.96 ± 0.038	1.281AspMet: 1.281 ± 0.015	2.015AspAsn: 2.015 ± 0.021	3.367AspPro: 3.367 ± 0.03	1.799AspGln: 1.799 ± 0.02	3.115AspArg: 3.115 ± 0.03	4.273AspSer: 4.273 ± 0.035	2.995AspThr: 2.995 ± 0.025	3.666AspVal: 3.666 ± 0.035	0.834AspTrp: 0.834 ± 0.013	1.561AspTyr: 1.561 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.175GluAla: 5.175 ± 0.04	0.651GluCys: 0.651 ± 0.014	4.276GluAsp: 4.276 ± 0.035	5.928GluGlu: 5.928 ± 0.066	2.045GluPhe: 2.045 ± 0.024	3.951GluGly: 3.951 ± 0.032	1.351GluHis: 1.351 ± 0.016	3.219GluIle: 3.219 ± 0.026	3.761GluLys: 3.761 ± 0.035	5.295GluLeu: 5.295 ± 0.041	1.454GluMet: 1.454 ± 0.017	2.433GluAsn: 2.433 ± 0.025	2.94GluPro: 2.94 ± 0.045	2.476GluGln: 2.476 ± 0.031	4.07GluArg: 4.07 ± 0.035	4.431GluSer: 4.431 ± 0.037	3.478GluThr: 3.478 ± 0.033	3.584GluVal: 3.584 ± 0.033	0.877GluTrp: 0.877 ± 0.013	1.703GluTyr: 1.703 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.909PheAla: 2.909 ± 0.025	0.56PheCys: 0.56 ± 0.011	2.286PheAsp: 2.286 ± 0.022	2.149PheGlu: 2.149 ± 0.023	1.53PhePhe: 1.53 ± 0.022	2.71PheGly: 2.71 ± 0.03	0.927PheHis: 0.927 ± 0.013	1.797PheIle: 1.797 ± 0.023	1.517PheLys: 1.517 ± 0.017	3.478PheLeu: 3.478 ± 0.031	0.754PheMet: 0.754 ± 0.012	1.401PheAsn: 1.401 ± 0.016	2.011PhePro: 2.011 ± 0.023	1.378PheGln: 1.378 ± 0.016	2.033PheArg: 2.033 ± 0.021	3.109PheSer: 3.109 ± 0.025	2.072PheThr: 2.072 ± 0.024	2.257PheVal: 2.257 ± 0.027	0.597PheTrp: 0.597 ± 0.012	1.089PheTyr: 1.089 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.107GlyAla: 5.107 ± 0.038	0.825GlyCys: 0.825 ± 0.013	3.757GlyAsp: 3.757 ± 0.03	3.894GlyGlu: 3.894 ± 0.038	2.637GlyPhe: 2.637 ± 0.026	6.101GlyGly: 6.101 ± 0.068	1.624GlyHis: 1.624 ± 0.024	3.489GlyIle: 3.489 ± 0.034	3.548GlyLys: 3.548 ± 0.03	5.734GlyLeu: 5.734 ± 0.035	1.553GlyMet: 1.553 ± 0.023	2.562GlyAsn: 2.562 ± 0.024	3.297GlyPro: 3.297 ± 0.032	2.485GlyGln: 2.485 ± 0.024	4.152GlyArg: 4.152 ± 0.032	5.663GlySer: 5.663 ± 0.037	3.811GlyThr: 3.811 ± 0.034	4.3GlyVal: 4.3 ± 0.036	1.095GlyTrp: 1.095 ± 0.017	2.07GlyTyr: 2.07 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.831HisAla: 1.831 ± 0.019	0.317HisCys: 0.317 ± 0.009	1.32HisAsp: 1.32 ± 0.016	1.305HisGlu: 1.305 ± 0.016	0.904HisPhe: 0.904 ± 0.016	1.701HisGly: 1.701 ± 0.02	0.937HisHis: 0.937 ± 0.021	1.272HisIle: 1.272 ± 0.016	0.923HisLys: 0.923 ± 0.014	2.278HisLeu: 2.278 ± 0.023	0.471HisMet: 0.471 ± 0.01	0.884HisAsn: 0.884 ± 0.014	1.731HisPro: 1.731 ± 0.023	1.001HisGln: 1.001 ± 0.017	1.571HisArg: 1.571 ± 0.02	1.952HisSer: 1.952 ± 0.022	1.328HisThr: 1.328 ± 0.014	1.396HisVal: 1.396 ± 0.018	0.337HisTrp: 0.337 ± 0.009	0.694HisTyr: 0.694 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.079IleAla: 4.079 ± 0.032	0.727IleCys: 0.727 ± 0.014	2.976IleAsp: 2.976 ± 0.031	2.887IleGlu: 2.887 ± 0.027	2.02IlePhe: 2.02 ± 0.021	3.07IleGly: 3.07 ± 0.033	1.217IleHis: 1.217 ± 0.017	2.585IleIle: 2.585 ± 0.027	2.186IleLys: 2.186 ± 0.026	4.696IleLeu: 4.696 ± 0.039	1.001IleMet: 1.001 ± 0.017	1.784IleAsn: 1.784 ± 0.021	3.316IlePro: 3.316 ± 0.029	1.896IleGln: 1.896 ± 0.02	2.932IleArg: 2.932 ± 0.027	4.153IleSer: 4.153 ± 0.031	2.839IleThr: 2.839 ± 0.027	3.125IleVal: 3.125 ± 0.026	0.684IleTrp: 0.684 ± 0.012	1.438IleTyr: 1.438 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.064LysAla: 4.064 ± 0.04	0.529LysCys: 0.529 ± 0.012	2.752LysAsp: 2.752 ± 0.03	3.484LysGlu: 3.484 ± 0.034	1.597LysPhe: 1.597 ± 0.021	3.018LysGly: 3.018 ± 0.03	1.126LysHis: 1.126 ± 0.017	2.309LysIle: 2.309 ± 0.026	3.358LysLys: 3.358 ± 0.048	4.272LysLeu: 4.272 ± 0.036	0.973LysMet: 0.973 ± 0.014	1.74LysAsn: 1.74 ± 0.022	2.847LysPro: 2.847 ± 0.028	1.889LysGln: 1.889 ± 0.023	3.587LysArg: 3.587 ± 0.035	3.602LysSer: 3.602 ± 0.031	2.71LysThr: 2.71 ± 0.023	2.826LysVal: 2.826 ± 0.028	0.673LysTrp: 0.673 ± 0.013	1.404LysTyr: 1.404 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.514LeuAla: 7.514 ± 0.043	1.191LeuCys: 1.191 ± 0.017	5.271LeuAsp: 5.271 ± 0.037	5.684LeuGlu: 5.684 ± 0.047	3.3LeuPhe: 3.3 ± 0.033	5.689LeuGly: 5.689 ± 0.036	2.316LeuHis: 2.316 ± 0.025	3.955LeuIle: 3.955 ± 0.04	4.331LeuLys: 4.331 ± 0.038	8.548LeuLeu: 8.548 ± 0.061	1.703LeuMet: 1.703 ± 0.023	3.169LeuAsn: 3.169 ± 0.026	5.55LeuPro: 5.55 ± 0.041	3.757LeuGln: 3.757 ± 0.034	5.905LeuArg: 5.905 ± 0.047	7.696LeuSer: 7.696 ± 0.049	4.757LeuThr: 4.757 ± 0.03	5.342LeuVal: 5.342 ± 0.041	1.117LeuTrp: 1.117 ± 0.018	2.336LeuTyr: 2.336 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.07MetAla: 2.07 ± 0.02	0.236MetCys: 0.236 ± 0.008	1.226MetAsp: 1.226 ± 0.016	1.337MetGlu: 1.337 ± 0.018	0.734MetPhe: 0.734 ± 0.014	1.434MetGly: 1.434 ± 0.018	0.459MetHis: 0.459 ± 0.01	0.941MetIle: 0.941 ± 0.015	1.025MetLys: 1.025 ± 0.015	1.799MetLeu: 1.799 ± 0.02	0.525MetMet: 0.525 ± 0.01	0.762MetAsn: 0.762 ± 0.012	1.157MetPro: 1.157 ± 0.017	0.81MetGln: 0.81 ± 0.014	1.251MetArg: 1.251 ± 0.019	1.809MetSer: 1.809 ± 0.02	1.19MetThr: 1.19 ± 0.018	1.285MetVal: 1.285 ± 0.017	0.254MetTrp: 0.254 ± 0.007	0.506MetTyr: 0.506 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.062AsnAla: 3.062 ± 0.026	0.467AsnCys: 0.467 ± 0.01	2.002AsnAsp: 2.002 ± 0.023	2.077AsnGlu: 2.077 ± 0.022	1.355AsnPhe: 1.355 ± 0.017	2.966AsnGly: 2.966 ± 0.031	0.9AsnHis: 0.9 ± 0.014	2.134AsnIle: 2.134 ± 0.02	1.593AsnLys: 1.593 ± 0.019	3.302AsnLeu: 3.302 ± 0.032	0.813AsnMet: 0.813 ± 0.012	1.821AsnAsn: 1.821 ± 0.029	2.625AsnPro: 2.625 ± 0.025	1.342AsnGln: 1.342 ± 0.019	2.06AsnArg: 2.06 ± 0.019	2.823AsnSer: 2.823 ± 0.026	2.174AsnThr: 2.174 ± 0.022	2.244AsnVal: 2.244 ± 0.022	0.51AsnTrp: 0.51 ± 0.011	1.002AsnTyr: 1.002 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.23ProAla: 5.23 ± 0.053	0.498ProCys: 0.498 ± 0.014	3.257ProAsp: 3.257 ± 0.025	3.868ProGlu: 3.868 ± 0.04	2.089ProPhe: 2.089 ± 0.025	3.806ProGly: 3.806 ± 0.041	1.453ProHis: 1.453 ± 0.018	2.666ProIle: 2.666 ± 0.023	2.712ProLys: 2.712 ± 0.029	4.988ProLeu: 4.988 ± 0.036	1.049ProMet: 1.049 ± 0.015	2.32ProAsn: 2.32 ± 0.023	5.843ProPro: 5.843 ± 0.076	2.641ProGln: 2.641 ± 0.033	3.533ProArg: 3.533 ± 0.038	6.567ProSer: 6.567 ± 0.06	4.311ProThr: 4.311 ± 0.04	3.463ProVal: 3.463 ± 0.034	0.691ProTrp: 0.691 ± 0.012	1.536ProTyr: 1.536 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.194GlnAla: 3.194 ± 0.03	0.423GlnCys: 0.423 ± 0.01	1.963GlnAsp: 1.963 ± 0.023	2.36GlnGlu: 2.36 ± 0.024	1.305GlnPhe: 1.305 ± 0.017	2.36GlnGly: 2.36 ± 0.024	1.155GlnHis: 1.155 ± 0.018	1.871GlnIle: 1.871 ± 0.021	1.949GlnLys: 1.949 ± 0.022	3.491GlnLeu: 3.491 ± 0.03	0.821GlnMet: 0.821 ± 0.013	1.537GlnAsn: 1.537 ± 0.02	2.662GlnPro: 2.662 ± 0.035	2.99GlnGln: 2.99 ± 0.057	2.732GlnArg: 2.732 ± 0.029	3.19GlnSer: 3.19 ± 0.027	2.28GlnThr: 2.28 ± 0.023	2.062GlnVal: 2.062 ± 0.022	0.533GlnTrp: 0.533 ± 0.012	1.1GlnTyr: 1.1 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.683ArgAla: 4.683 ± 0.035	0.745ArgCys: 0.745 ± 0.014	3.539ArgAsp: 3.539 ± 0.037	4.009ArgGlu: 4.009 ± 0.041	2.208ArgPhe: 2.208 ± 0.022	3.925ArgGly: 3.925 ± 0.038	1.635ArgHis: 1.635 ± 0.02	2.971ArgIle: 2.971 ± 0.024	3.609ArgLys: 3.609 ± 0.032	5.481ArgLeu: 5.481 ± 0.035	1.304ArgMet: 1.304 ± 0.014	2.395ArgAsn: 2.395 ± 0.022	3.556ArgPro: 3.556 ± 0.033	2.6ArgGln: 2.6 ± 0.028	5.418ArgArg: 5.418 ± 0.046	5.155ArgSer: 5.155 ± 0.042	3.329ArgThr: 3.329 ± 0.025	3.442ArgVal: 3.442 ± 0.027	0.903ArgTrp: 0.903 ± 0.014	1.694ArgTyr: 1.694 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.696SerAla: 6.696 ± 0.045	0.878SerCys: 0.878 ± 0.016	4.31SerAsp: 4.31 ± 0.034	4.302SerGlu: 4.302 ± 0.033	3.067SerPhe: 3.067 ± 0.028	5.59SerGly: 5.59 ± 0.041	2.051SerHis: 2.051 ± 0.023	4.086SerIle: 4.086 ± 0.032	3.854SerLys: 3.854 ± 0.031	7.556SerLeu: 7.556 ± 0.048	1.722SerMet: 1.722 ± 0.02	3.142SerAsn: 3.142 ± 0.026	6.111SerPro: 6.111 ± 0.059	3.386SerGln: 3.386 ± 0.034	5.448SerArg: 5.448 ± 0.04	9.974SerSer: 9.974 ± 0.083	5.836SerThr: 5.836 ± 0.043	4.552SerVal: 4.552 ± 0.038	1.067SerTrp: 1.067 ± 0.018	2.05SerTyr: 2.05 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.169ThrAla: 5.169 ± 0.037	0.722ThrCys: 0.722 ± 0.013	2.802ThrAsp: 2.802 ± 0.027	3.143ThrGlu: 3.143 ± 0.026	2.205ThrPhe: 2.205 ± 0.02	3.985ThrGly: 3.985 ± 0.03	1.31ThrHis: 1.31 ± 0.018	3.079ThrIle: 3.079 ± 0.026	2.572ThrLys: 2.572 ± 0.026	5.192ThrLeu: 5.192 ± 0.038	1.15ThrMet: 1.15 ± 0.018	2.123ThrAsn: 2.123 ± 0.02	4.546ThrPro: 4.546 ± 0.05	2.027ThrGln: 2.027 ± 0.02	3.151ThrArg: 3.151 ± 0.027	5.554ThrSer: 5.554 ± 0.042	4.747ThrThr: 4.747 ± 0.055	3.563ThrVal: 3.563 ± 0.032	0.767ThrTrp: 0.767 ± 0.012	1.56ThrTyr: 1.56 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	4.933ValAla: 4.933 ± 0.037	0.793ValCys: 0.793 ± 0.013	3.734ValAsp: 3.734 ± 0.032	3.996ValGlu: 3.996 ± 0.04	2.342ValPhe: 2.342 ± 0.023	3.94ValGly: 3.94 ± 0.035	1.344ValHis: 1.344 ± 0.018	2.902ValIle: 2.902 ± 0.029	2.939ValLys: 2.939 ± 0.024	5.404ValLeu: 5.404 ± 0.037	1.246ValMet: 1.246 ± 0.016	2.18ValAsn: 2.18 ± 0.023	3.47ValPro: 3.47 ± 0.031	2.261ValGln: 2.261 ± 0.023	3.463ValArg: 3.463 ± 0.028	4.677ValSer: 4.677 ± 0.036	3.365ValThr: 3.365 ± 0.028	4.221ValVal: 4.221 ± 0.036	0.828ValTrp: 0.828 ± 0.014	1.66ValTyr: 1.66 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.045TrpAla: 1.045 ± 0.018	0.178TrpCys: 0.178 ± 0.006	0.874TrpAsp: 0.874 ± 0.015	0.845TrpGlu: 0.845 ± 0.015	0.495TrpPhe: 0.495 ± 0.011	0.853TrpGly: 0.853 ± 0.013	0.321TrpHis: 0.321 ± 0.009	0.738TrpIle: 0.738 ± 0.013	0.806TrpLys: 0.806 ± 0.014	1.273TrpLeu: 1.273 ± 0.018	0.344TrpMet: 0.344 ± 0.008	0.585TrpAsn: 0.585 ± 0.012	0.57TrpPro: 0.57 ± 0.012	0.517TrpGln: 0.517 ± 0.01	0.949TrpArg: 0.949 ± 0.015	0.994TrpSer: 0.994 ± 0.015	0.816TrpThr: 0.816 ± 0.014	0.826TrpVal: 0.826 ± 0.011	0.253TrpTrp: 0.253 ± 0.007	0.375TrpTyr: 0.375 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.051TyrAla: 2.051 ± 0.024	0.394TyrCys: 0.394 ± 0.009	1.619TyrAsp: 1.619 ± 0.02	1.537TyrGlu: 1.537 ± 0.018	1.184TyrPhe: 1.184 ± 0.017	1.941TyrGly: 1.941 ± 0.02	0.767TyrHis: 0.767 ± 0.011	1.456TyrIle: 1.456 ± 0.018	1.101TyrLys: 1.101 ± 0.018	2.658TyrLeu: 2.658 ± 0.025	0.6TyrMet: 0.6 ± 0.012	1.068TyrAsn: 1.068 ± 0.015	1.543TyrPro: 1.543 ± 0.022	1.054TyrGln: 1.054 ± 0.018	1.633TyrArg: 1.633 ± 0.018	2.038TyrSer: 2.038 ± 0.022	1.562TyrThr: 1.562 ± 0.021	1.568TyrVal: 1.568 ± 0.02	0.401TyrTrp: 0.401 ± 0.009	0.906TyrTyr: 0.906 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9934 proteins (4766470 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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