Amino acid dipepetide frequency for Phormidesmis priestleyi ULC007

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.467AlaAla: 8.467 ± 0.101	0.856AlaCys: 0.856 ± 0.028	4.84AlaAsp: 4.84 ± 0.063	5.468AlaGlu: 5.468 ± 0.073	3.218AlaPhe: 3.218 ± 0.051	5.776AlaGly: 5.776 ± 0.071	1.582AlaHis: 1.582 ± 0.037	7.738AlaIle: 7.738 ± 0.087	3.924AlaLys: 3.924 ± 0.061	9.698AlaLeu: 9.698 ± 0.093	1.842AlaMet: 1.842 ± 0.039	3.135AlaAsn: 3.135 ± 0.059	3.578AlaPro: 3.578 ± 0.054	4.784AlaGln: 4.784 ± 0.066	4.076AlaArg: 4.076 ± 0.055	5.133AlaSer: 5.133 ± 0.067	5.124AlaThr: 5.124 ± 0.072	5.901AlaVal: 5.901 ± 0.055	1.091AlaTrp: 1.091 ± 0.029	2.334AlaTyr: 2.334 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.666CysAla: 0.666 ± 0.022	0.149CysCys: 0.149 ± 0.01	0.588CysAsp: 0.588 ± 0.022	0.51CysGlu: 0.51 ± 0.019	0.394CysPhe: 0.394 ± 0.017	0.752CysGly: 0.752 ± 0.025	0.277CysHis: 0.277 ± 0.014	0.465CysIle: 0.465 ± 0.015	0.32CysLys: 0.32 ± 0.016	1.111CysLeu: 1.111 ± 0.027	0.153CysMet: 0.153 ± 0.01	0.314CysAsn: 0.314 ± 0.016	0.546CysPro: 0.546 ± 0.021	0.529CysGln: 0.529 ± 0.016	0.577CysArg: 0.577 ± 0.02	0.596CysSer: 0.596 ± 0.019	0.467CysThr: 0.467 ± 0.017	0.605CysVal: 0.605 ± 0.024	0.16CysTrp: 0.16 ± 0.011	0.319CysTyr: 0.319 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.346AspAla: 4.346 ± 0.055	0.528AspCys: 0.528 ± 0.019	2.601AspAsp: 2.601 ± 0.051	3.033AspGlu: 3.033 ± 0.052	2.255AspPhe: 2.255 ± 0.037	3.437AspGly: 3.437 ± 0.053	1.028AspHis: 1.028 ± 0.025	2.652AspIle: 2.652 ± 0.044	1.65AspLys: 1.65 ± 0.039	6.62AspLeu: 6.62 ± 0.084	0.757AspMet: 0.757 ± 0.028	1.491AspAsn: 1.491 ± 0.033	2.969AspPro: 2.969 ± 0.047	2.675AspGln: 2.675 ± 0.045	5.298AspArg: 5.298 ± 0.065	3.068AspSer: 3.068 ± 0.05	2.317AspThr: 2.317 ± 0.04	3.21AspVal: 3.21 ± 0.049	0.957AspTrp: 0.957 ± 0.025	1.908AspTyr: 1.908 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	5.823GluAla: 5.823 ± 0.069	0.451GluCys: 0.451 ± 0.017	2.638GluAsp: 2.638 ± 0.048	3.401GluGlu: 3.401 ± 0.064	2.402GluPhe: 2.402 ± 0.042	3.322GluGly: 3.322 ± 0.05	0.956GluHis: 0.956 ± 0.026	4.095GluIle: 4.095 ± 0.056	2.827GluLys: 2.827 ± 0.045	6.599GluLeu: 6.599 ± 0.079	1.423GluMet: 1.423 ± 0.031	2.055GluAsn: 2.055 ± 0.032	2.611GluPro: 2.611 ± 0.039	3.493GluGln: 3.493 ± 0.053	3.503GluArg: 3.503 ± 0.053	3.526GluSer: 3.526 ± 0.054	3.636GluThr: 3.636 ± 0.046	4.379GluVal: 4.379 ± 0.059	0.78GluTrp: 0.78 ± 0.018	1.377GluTyr: 1.377 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.211PheAla: 3.211 ± 0.044	0.503PheCys: 0.503 ± 0.018	2.31PheAsp: 2.31 ± 0.044	2.331PheGlu: 2.331 ± 0.05	1.542PhePhe: 1.542 ± 0.035	2.891PheGly: 2.891 ± 0.05	0.687PheHis: 0.687 ± 0.021	1.87PheIle: 1.87 ± 0.038	1.471PheLys: 1.471 ± 0.031	4.083PheLeu: 4.083 ± 0.059	0.63PheMet: 0.63 ± 0.022	1.564PheAsn: 1.564 ± 0.04	1.767PhePro: 1.767 ± 0.038	1.734PheGln: 1.734 ± 0.034	1.978PheArg: 1.978 ± 0.04	2.899PheSer: 2.899 ± 0.054	2.094PheThr: 2.094 ± 0.035	2.553PheVal: 2.553 ± 0.05	0.729PheTrp: 0.729 ± 0.023	1.275PheTyr: 1.275 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	5.537GlyAla: 5.537 ± 0.074	0.761GlyCys: 0.761 ± 0.021	3.587GlyAsp: 3.587 ± 0.054	3.711GlyGlu: 3.711 ± 0.051	2.976GlyPhe: 2.976 ± 0.046	4.798GlyGly: 4.798 ± 0.086	1.308GlyHis: 1.308 ± 0.039	4.527GlyIle: 4.527 ± 0.063	3.467GlyLys: 3.467 ± 0.053	7.237GlyLeu: 7.237 ± 0.084	1.592GlyMet: 1.592 ± 0.034	2.544GlyAsn: 2.544 ± 0.055	1.135GlyPro: 1.135 ± 0.033	3.426GlyGln: 3.426 ± 0.052	3.579GlyArg: 3.579 ± 0.051	4.454GlySer: 4.454 ± 0.072	4.168GlyThr: 4.168 ± 0.076	4.988GlyVal: 4.988 ± 0.062	1.198GlyTrp: 1.198 ± 0.028	2.281GlyTyr: 2.281 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.261HisAla: 1.261 ± 0.033	0.291HisCys: 0.291 ± 0.014	0.999HisAsp: 0.999 ± 0.025	0.982HisGlu: 0.982 ± 0.025	0.787HisPhe: 0.787 ± 0.024	1.115HisGly: 1.115 ± 0.03	0.633HisHis: 0.633 ± 0.023	0.935HisIle: 0.935 ± 0.028	0.631HisLys: 0.631 ± 0.021	2.479HisLeu: 2.479 ± 0.046	0.274HisMet: 0.274 ± 0.013	0.667HisAsn: 0.667 ± 0.02	1.457HisPro: 1.457 ± 0.032	1.217HisGln: 1.217 ± 0.031	1.23HisArg: 1.23 ± 0.027	1.208HisSer: 1.208 ± 0.027	0.959HisThr: 0.959 ± 0.029	0.928HisVal: 0.928 ± 0.024	0.39HisTrp: 0.39 ± 0.017	0.767HisTyr: 0.767 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	7.543IleAla: 7.543 ± 0.085	0.629IleCys: 0.629 ± 0.02	3.645IleAsp: 3.645 ± 0.053	4.207IleGlu: 4.207 ± 0.058	2.02IlePhe: 2.02 ± 0.039	4.476IleGly: 4.476 ± 0.069	1.185IleHis: 1.185 ± 0.031	2.482IleIle: 2.482 ± 0.044	2.205IleLys: 2.205 ± 0.039	5.992IleLeu: 5.992 ± 0.073	0.708IleMet: 0.708 ± 0.025	2.16IleAsn: 2.16 ± 0.04	3.228IlePro: 3.228 ± 0.045	2.944IleGln: 2.944 ± 0.047	3.337IleArg: 3.337 ± 0.056	3.945IleSer: 3.945 ± 0.055	3.21IleThr: 3.21 ± 0.049	4.74IleVal: 4.74 ± 0.063	0.756IleTrp: 0.756 ± 0.021	1.6IleTyr: 1.6 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.903LysAla: 3.903 ± 0.052	0.247LysCys: 0.247 ± 0.014	1.962LysAsp: 1.962 ± 0.042	2.142LysGlu: 2.142 ± 0.036	1.434LysPhe: 1.434 ± 0.028	2.562LysGly: 2.562 ± 0.039	0.741LysHis: 0.741 ± 0.023	2.557LysIle: 2.557 ± 0.049	1.776LysLys: 1.776 ± 0.042	4.634LysLeu: 4.634 ± 0.056	0.861LysMet: 0.861 ± 0.022	1.435LysAsn: 1.435 ± 0.032	2.485LysPro: 2.485 ± 0.038	2.423LysGln: 2.423 ± 0.042	2.457LysArg: 2.457 ± 0.044	2.705LysSer: 2.705 ± 0.048	2.9LysThr: 2.9 ± 0.049	2.907LysVal: 2.907 ± 0.049	0.425LysTrp: 0.425 ± 0.017	0.929LysTyr: 0.929 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	9.721LeuAla: 9.721 ± 0.095	0.997LeuCys: 0.997 ± 0.027	5.972LeuAsp: 5.972 ± 0.069	7.142LeuGlu: 7.142 ± 0.082	3.694LeuPhe: 3.694 ± 0.056	7.416LeuGly: 7.416 ± 0.082	2.032LeuHis: 2.032 ± 0.036	6.413LeuIle: 6.413 ± 0.068	5.559LeuLys: 5.559 ± 0.057	11.36LeuLeu: 11.36 ± 0.123	2.269LeuMet: 2.269 ± 0.044	4.382LeuAsn: 4.382 ± 0.056	5.782LeuPro: 5.782 ± 0.071	5.645LeuGln: 5.645 ± 0.088	6.17LeuArg: 6.17 ± 0.081	7.996LeuSer: 7.996 ± 0.08	6.968LeuThr: 6.968 ± 0.071	7.268LeuVal: 7.268 ± 0.081	1.43LeuTrp: 1.43 ± 0.046	2.652LeuTyr: 2.652 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	1.822MetAla: 1.822 ± 0.041	0.103MetCys: 0.103 ± 0.008	0.794MetAsp: 0.794 ± 0.021	0.913MetGlu: 0.913 ± 0.023	0.528MetPhe: 0.528 ± 0.019	1.432MetGly: 1.432 ± 0.036	0.305MetHis: 0.305 ± 0.015	1.134MetIle: 1.134 ± 0.028	0.841MetLys: 0.841 ± 0.025	1.948MetLeu: 1.948 ± 0.04	0.445MetMet: 0.445 ± 0.017	0.824MetAsn: 0.824 ± 0.023	1.069MetPro: 1.069 ± 0.027	1.073MetGln: 1.073 ± 0.024	1.032MetArg: 1.032 ± 0.026	1.365MetSer: 1.365 ± 0.032	1.475MetThr: 1.475 ± 0.029	1.376MetVal: 1.376 ± 0.034	0.145MetTrp: 0.145 ± 0.01	0.292MetTyr: 0.292 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.073AsnAla: 3.073 ± 0.055	0.387AsnCys: 0.387 ± 0.017	1.609AsnAsp: 1.609 ± 0.035	1.584AsnGlu: 1.584 ± 0.035	1.455AsnPhe: 1.455 ± 0.034	2.567AsnGly: 2.567 ± 0.055	0.845AsnHis: 0.845 ± 0.024	1.727AsnIle: 1.727 ± 0.033	1.071AsnLys: 1.071 ± 0.031	4.585AsnLeu: 4.585 ± 0.071	0.462AsnMet: 0.462 ± 0.018	1.228AsnAsn: 1.228 ± 0.035	2.725AsnPro: 2.725 ± 0.045	2.359AsnGln: 2.359 ± 0.038	2.33AsnArg: 2.33 ± 0.042	2.402AsnSer: 2.402 ± 0.043	1.768AsnThr: 1.768 ± 0.036	2.192AsnVal: 2.192 ± 0.042	0.612AsnTrp: 0.612 ± 0.021	1.114AsnTyr: 1.114 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	3.857ProAla: 3.857 ± 0.056	0.358ProCys: 0.358 ± 0.015	3.485ProAsp: 3.485 ± 0.053	3.553ProGlu: 3.553 ± 0.05	1.846ProPhe: 1.846 ± 0.035	3.277ProGly: 3.277 ± 0.05	0.918ProHis: 0.918 ± 0.026	3.389ProIle: 3.389 ± 0.048	2.121ProLys: 2.121 ± 0.043	4.808ProLeu: 4.808 ± 0.06	0.881ProMet: 0.881 ± 0.024	2.069ProAsn: 2.069 ± 0.043	2.395ProPro: 2.395 ± 0.055	2.508ProGln: 2.508 ± 0.046	2.036ProArg: 2.036 ± 0.038	3.317ProSer: 3.317 ± 0.054	3.208ProThr: 3.208 ± 0.057	3.247ProVal: 3.247 ± 0.052	0.634ProTrp: 0.634 ± 0.021	1.228ProTyr: 1.228 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	5.314GlnAla: 5.314 ± 0.069	0.392GlnCys: 0.392 ± 0.017	2.259GlnAsp: 2.259 ± 0.042	3.129GlnGlu: 3.129 ± 0.056	1.942GlnPhe: 1.942 ± 0.038	3.35GlnGly: 3.35 ± 0.05	0.952GlnHis: 0.952 ± 0.024	3.671GlnIle: 3.671 ± 0.054	2.394GlnLys: 2.394 ± 0.044	5.821GlnLeu: 5.821 ± 0.065	1.104GlnMet: 1.104 ± 0.024	1.859GlnAsn: 1.859 ± 0.034	2.937GlnPro: 2.937 ± 0.049	3.784GlnGln: 3.784 ± 0.067	3.364GlnArg: 3.364 ± 0.049	3.478GlnSer: 3.478 ± 0.046	3.645GlnThr: 3.645 ± 0.052	4.078GlnVal: 4.078 ± 0.058	0.71GlnTrp: 0.71 ± 0.023	1.132GlnTyr: 1.132 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	4.024ArgAla: 4.024 ± 0.056	0.574ArgCys: 0.574 ± 0.018	3.105ArgAsp: 3.105 ± 0.048	3.409ArgGlu: 3.409 ± 0.05	2.536ArgPhe: 2.536 ± 0.042	3.249ArgGly: 3.249 ± 0.057	1.205ArgHis: 1.205 ± 0.033	3.255ArgIle: 3.255 ± 0.044	2.25ArgLys: 2.25 ± 0.042	6.85ArgLeu: 6.85 ± 0.074	1.127ArgMet: 1.127 ± 0.029	1.984ArgAsn: 1.984 ± 0.034	2.411ArgPro: 2.411 ± 0.041	3.657ArgGln: 3.657 ± 0.057	3.545ArgArg: 3.545 ± 0.053	4.715ArgSer: 4.715 ± 0.056	2.797ArgThr: 2.797 ± 0.043	4.152ArgVal: 4.152 ± 0.058	0.941ArgTrp: 0.941 ± 0.022	2.0ArgTyr: 2.0 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	5.616SerAla: 5.616 ± 0.073	0.557SerCys: 0.557 ± 0.019	3.866SerAsp: 3.866 ± 0.052	3.854SerGlu: 3.854 ± 0.048	2.501SerPhe: 2.501 ± 0.044	4.935SerGly: 4.935 ± 0.083	1.318SerHis: 1.318 ± 0.029	3.601SerIle: 3.601 ± 0.053	2.472SerLys: 2.472 ± 0.046	7.715SerLeu: 7.715 ± 0.079	1.243SerMet: 1.243 ± 0.027	2.348SerAsn: 2.348 ± 0.043	3.66SerPro: 3.66 ± 0.064	3.786SerGln: 3.786 ± 0.063	3.613SerArg: 3.613 ± 0.048	4.597SerSer: 4.597 ± 0.068	3.693SerThr: 3.693 ± 0.061	4.306SerVal: 4.306 ± 0.06	0.894SerTrp: 0.894 ± 0.028	1.638SerTyr: 1.638 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	5.171ThrAla: 5.171 ± 0.064	0.508ThrCys: 0.508 ± 0.018	2.815ThrAsp: 2.815 ± 0.046	3.105ThrGlu: 3.105 ± 0.046	2.155ThrPhe: 2.155 ± 0.044	4.225ThrGly: 4.225 ± 0.077	1.152ThrHis: 1.152 ± 0.026	4.261ThrIle: 4.261 ± 0.07	1.912ThrLys: 1.912 ± 0.038	6.828ThrLeu: 6.828 ± 0.081	0.87ThrMet: 0.87 ± 0.023	1.925ThrAsn: 1.925 ± 0.04	3.468ThrPro: 3.468 ± 0.06	3.232ThrGln: 3.232 ± 0.049	2.842ThrArg: 2.842 ± 0.046	3.621ThrSer: 3.621 ± 0.055	3.433ThrThr: 3.433 ± 0.061	4.134ThrVal: 4.134 ± 0.056	0.749ThrTrp: 0.749 ± 0.024	1.597ThrTyr: 1.597 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	6.019ValAla: 6.019 ± 0.074	0.742ValCys: 0.742 ± 0.026	3.626ValAsp: 3.626 ± 0.052	4.43ValGlu: 4.43 ± 0.056	2.636ValPhe: 2.636 ± 0.046	4.709ValGly: 4.709 ± 0.063	1.125ValHis: 1.125 ± 0.027	4.135ValIle: 4.135 ± 0.058	3.091ValLys: 3.091 ± 0.048	7.279ValLeu: 7.279 ± 0.074	1.537ValMet: 1.537 ± 0.031	2.578ValAsn: 2.578 ± 0.05	3.277ValPro: 3.277 ± 0.054	3.159ValGln: 3.159 ± 0.055	3.857ValArg: 3.857 ± 0.058	4.628ValSer: 4.628 ± 0.06	4.138ValThr: 4.138 ± 0.059	4.923ValVal: 4.923 ± 0.056	0.954ValTrp: 0.954 ± 0.028	1.774ValTyr: 1.774 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.097TrpAla: 1.097 ± 0.026	0.148TrpCys: 0.148 ± 0.011	0.609TrpAsp: 0.609 ± 0.025	0.806TrpGlu: 0.806 ± 0.027	0.617TrpPhe: 0.617 ± 0.022	0.954TrpGly: 0.954 ± 0.027	0.356TrpHis: 0.356 ± 0.016	0.807TrpIle: 0.807 ± 0.026	0.611TrpLys: 0.611 ± 0.02	1.929TrpLeu: 1.929 ± 0.041	0.365TrpMet: 0.365 ± 0.015	0.604TrpAsn: 0.604 ± 0.021	0.113TrpPro: 0.113 ± 0.009	1.133TrpGln: 1.133 ± 0.028	0.892TrpArg: 0.892 ± 0.025	0.905TrpSer: 0.905 ± 0.026	0.659TrpThr: 0.659 ± 0.019	1.075TrpVal: 1.075 ± 0.029	0.252TrpTrp: 0.252 ± 0.014	0.367TrpTyr: 0.367 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.093TyrAla: 2.093 ± 0.038	0.317TyrCys: 0.317 ± 0.014	1.488TyrAsp: 1.488 ± 0.036	1.591TyrGlu: 1.591 ± 0.035	1.182TyrPhe: 1.182 ± 0.033	2.027TyrGly: 2.027 ± 0.04	0.606TyrHis: 0.606 ± 0.02	1.298TyrIle: 1.298 ± 0.028	0.892TyrLys: 0.892 ± 0.019	3.292TyrLeu: 3.292 ± 0.047	0.372TyrMet: 0.372 ± 0.017	0.93TyrAsn: 0.93 ± 0.028	1.522TyrPro: 1.522 ± 0.032	1.756TyrGln: 1.756 ± 0.039	2.074TyrArg: 2.074 ± 0.04	1.656TyrSer: 1.656 ± 0.035	1.345TyrThr: 1.345 ± 0.031	1.653TyrVal: 1.653 ± 0.031	0.491TyrTrp: 0.491 ± 0.017	0.914TyrTyr: 0.914 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5141 proteins (1552174 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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