Amino acid dipepetide frequency for Drosophila lebanonensis (Fruit fly) (Scaptodrosophila lebanonensis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.483AlaAla: 9.483 ± 0.09	1.159AlaCys: 1.159 ± 0.034	3.534AlaAsp: 3.534 ± 0.024	4.698AlaGlu: 4.698 ± 0.029	2.15AlaPhe: 2.15 ± 0.018	4.594AlaGly: 4.594 ± 0.031	1.773AlaHis: 1.773 ± 0.016	3.55AlaIle: 3.55 ± 0.023	4.126AlaLys: 4.126 ± 0.026	6.538AlaLeu: 6.538 ± 0.037	1.701AlaMet: 1.701 ± 0.013	3.504AlaAsn: 3.504 ± 0.024	4.16AlaPro: 4.16 ± 0.047	3.616AlaGln: 3.616 ± 0.027	3.392AlaArg: 3.392 ± 0.022	6.192AlaSer: 6.192 ± 0.041	5.434AlaThr: 5.434 ± 0.037	4.454AlaVal: 4.454 ± 0.024	0.566AlaTrp: 0.566 ± 0.009	1.792AlaTyr: 1.792 ± 0.016	0.001AlaXaa: 0.001 ± 0.0
Cys	1.224CysAla: 1.224 ± 0.021	0.471CysCys: 0.471 ± 0.009	1.037CysAsp: 1.037 ± 0.014	1.125CysGlu: 1.125 ± 0.019	0.681CysPhe: 0.681 ± 0.01	1.274CysGly: 1.274 ± 0.042	0.469CysHis: 0.469 ± 0.01	0.993CysIle: 0.993 ± 0.029	1.008CysLys: 1.008 ± 0.014	1.614CysLeu: 1.614 ± 0.028	0.395CysMet: 0.395 ± 0.007	0.918CysAsn: 0.918 ± 0.014	0.91CysPro: 0.91 ± 0.034	0.75CysGln: 0.75 ± 0.025	1.039CysArg: 1.039 ± 0.046	1.47CysSer: 1.47 ± 0.028	0.99CysThr: 0.99 ± 0.022	1.139CysVal: 1.139 ± 0.029	0.188CysTrp: 0.188 ± 0.004	0.548CysTyr: 0.548 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.84AspAla: 3.84 ± 0.024	0.951AspCys: 0.951 ± 0.02	3.987AspAsp: 3.987 ± 0.045	4.404AspGlu: 4.404 ± 0.03	2.082AspPhe: 2.082 ± 0.017	3.107AspGly: 3.107 ± 0.029	1.056AspHis: 1.056 ± 0.01	3.039AspIle: 3.039 ± 0.028	2.841AspLys: 2.841 ± 0.046	4.634AspLeu: 4.634 ± 0.029	1.302AspMet: 1.302 ± 0.011	2.458AspAsn: 2.458 ± 0.022	2.352AspPro: 2.352 ± 0.04	1.746AspGln: 1.746 ± 0.013	2.334AspArg: 2.334 ± 0.02	3.848AspSer: 3.848 ± 0.026	2.607AspThr: 2.607 ± 0.018	3.432AspVal: 3.432 ± 0.021	0.596AspTrp: 0.596 ± 0.009	1.767AspTyr: 1.767 ± 0.014	0.0AspXaa: 0.0 ± 0.0
Glu	4.547GluAla: 4.547 ± 0.03	1.16GluCys: 1.16 ± 0.042	3.736GluAsp: 3.736 ± 0.036	5.599GluGlu: 5.599 ± 0.069	2.081GluPhe: 2.081 ± 0.018	2.794GluGly: 2.794 ± 0.027	1.74GluHis: 1.74 ± 0.014	3.297GluIle: 3.297 ± 0.023	4.26GluLys: 4.26 ± 0.043	6.435GluLeu: 6.435 ± 0.043	1.512GluMet: 1.512 ± 0.015	3.033GluAsn: 3.033 ± 0.02	2.903GluPro: 2.903 ± 0.034	3.705GluGln: 3.705 ± 0.03	4.126GluArg: 4.126 ± 0.031	4.344GluSer: 4.344 ± 0.034	3.434GluThr: 3.434 ± 0.033	3.509GluVal: 3.509 ± 0.036	0.559GluTrp: 0.559 ± 0.008	1.814GluTyr: 1.814 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.142PheAla: 2.142 ± 0.017	0.694PheCys: 0.694 ± 0.009	2.014PheAsp: 2.014 ± 0.016	2.09PheGlu: 2.09 ± 0.017	1.345PhePhe: 1.345 ± 0.017	2.254PheGly: 2.254 ± 0.026	0.849PheHis: 0.849 ± 0.01	1.836PheIle: 1.836 ± 0.017	1.84PheLys: 1.84 ± 0.015	3.116PheLeu: 3.116 ± 0.027	0.83PheMet: 0.83 ± 0.011	1.725PheAsn: 1.725 ± 0.016	1.333PhePro: 1.333 ± 0.014	1.362PheGln: 1.362 ± 0.013	1.802PheArg: 1.802 ± 0.019	2.45PheSer: 2.45 ± 0.017	1.765PheThr: 1.765 ± 0.015	2.287PheVal: 2.287 ± 0.019	0.394PheTrp: 0.394 ± 0.007	1.221PheTyr: 1.221 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	4.503GlyAla: 4.503 ± 0.034	0.96GlyCys: 0.96 ± 0.019	2.94GlyAsp: 2.94 ± 0.024	3.122GlyGlu: 3.122 ± 0.028	1.995GlyPhe: 1.995 ± 0.02	6.064GlyGly: 6.064 ± 0.077	1.464GlyHis: 1.464 ± 0.015	2.828GlyIle: 2.828 ± 0.017	3.014GlyLys: 3.014 ± 0.024	4.398GlyLeu: 4.398 ± 0.026	1.23GlyMet: 1.23 ± 0.015	3.061GlyAsn: 3.061 ± 0.025	2.323GlyPro: 2.323 ± 0.025	2.243GlyGln: 2.243 ± 0.019	2.868GlyArg: 2.868 ± 0.017	5.419GlySer: 5.419 ± 0.04	3.247GlyThr: 3.247 ± 0.021	3.404GlyVal: 3.404 ± 0.021	0.571GlyTrp: 0.571 ± 0.009	1.869GlyTyr: 1.869 ± 0.021	0.001GlyXaa: 0.001 ± 0.0
His	1.698HisAla: 1.698 ± 0.014	0.549HisCys: 0.549 ± 0.01	1.128HisAsp: 1.128 ± 0.011	1.466HisGlu: 1.466 ± 0.014	1.031HisPhe: 1.031 ± 0.009	1.415HisGly: 1.415 ± 0.013	1.283HisHis: 1.283 ± 0.022	1.415HisIle: 1.415 ± 0.013	1.385HisLys: 1.385 ± 0.011	2.424HisLeu: 2.424 ± 0.017	0.732HisMet: 0.732 ± 0.009	1.323HisAsn: 1.323 ± 0.013	1.28HisPro: 1.28 ± 0.013	1.657HisGln: 1.657 ± 0.021	1.371HisArg: 1.371 ± 0.014	2.105HisSer: 2.105 ± 0.018	1.423HisThr: 1.423 ± 0.012	1.455HisVal: 1.455 ± 0.013	0.289HisTrp: 0.289 ± 0.005	0.865HisTyr: 0.865 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	3.564IleAla: 3.564 ± 0.022	1.164IleCys: 1.164 ± 0.024	2.907IleAsp: 2.907 ± 0.022	3.473IleGlu: 3.473 ± 0.031	2.014IlePhe: 2.014 ± 0.018	2.711IleGly: 2.711 ± 0.024	1.063IleHis: 1.063 ± 0.011	2.831IleIle: 2.831 ± 0.021	3.059IleLys: 3.059 ± 0.027	4.154IleLeu: 4.154 ± 0.026	1.162IleMet: 1.162 ± 0.011	2.648IleAsn: 2.648 ± 0.025	2.299IlePro: 2.299 ± 0.018	1.971IleGln: 1.971 ± 0.015	2.392IleArg: 2.392 ± 0.017	4.069IleSer: 4.069 ± 0.024	3.005IleThr: 3.005 ± 0.029	3.29IleVal: 3.29 ± 0.024	0.511IleTrp: 0.511 ± 0.007	1.664IleTyr: 1.664 ± 0.015	0.001IleXaa: 0.001 ± 0.0
Lys	3.674LysAla: 3.674 ± 0.035	1.123LysCys: 1.123 ± 0.024	2.91LysAsp: 2.91 ± 0.034	3.853LysGlu: 3.853 ± 0.033	1.898LysPhe: 1.898 ± 0.018	2.295LysGly: 2.295 ± 0.019	1.479LysHis: 1.479 ± 0.014	2.903LysIle: 2.903 ± 0.027	4.278LysLys: 4.278 ± 0.064	5.507LysLeu: 5.507 ± 0.037	1.407LysMet: 1.407 ± 0.011	2.593LysAsn: 2.593 ± 0.018	3.272LysPro: 3.272 ± 0.083	3.003LysGln: 3.003 ± 0.021	3.811LysArg: 3.811 ± 0.023	4.311LysSer: 4.311 ± 0.032	3.268LysThr: 3.268 ± 0.023	3.021LysVal: 3.021 ± 0.03	0.607LysTrp: 0.607 ± 0.012	1.819LysTyr: 1.819 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	6.427LeuAla: 6.427 ± 0.031	1.64LeuCys: 1.64 ± 0.017	4.793LeuAsp: 4.793 ± 0.029	6.123LeuGlu: 6.123 ± 0.044	2.826LeuPhe: 2.826 ± 0.024	4.509LeuGly: 4.509 ± 0.028	2.499LeuHis: 2.499 ± 0.02	4.266LeuIle: 4.266 ± 0.026	5.405LeuLys: 5.405 ± 0.032	8.87LeuLeu: 8.87 ± 0.063	1.944LeuMet: 1.944 ± 0.014	4.49LeuAsn: 4.49 ± 0.026	4.961LeuPro: 4.961 ± 0.027	5.459LeuGln: 5.459 ± 0.038	5.413LeuArg: 5.413 ± 0.034	6.904LeuSer: 6.904 ± 0.036	4.849LeuThr: 4.849 ± 0.025	4.835LeuVal: 4.835 ± 0.03	0.822LeuTrp: 0.822 ± 0.01	2.44LeuTyr: 2.44 ± 0.02	0.001LeuXaa: 0.001 ± 0.0
Met	1.784MetAla: 1.784 ± 0.013	0.416MetCys: 0.416 ± 0.007	1.338MetAsp: 1.338 ± 0.012	1.546MetGlu: 1.546 ± 0.013	0.752MetPhe: 0.752 ± 0.009	1.276MetGly: 1.276 ± 0.014	0.656MetHis: 0.656 ± 0.009	0.88MetIle: 0.88 ± 0.011	1.184MetLys: 1.184 ± 0.012	2.192MetLeu: 2.192 ± 0.02	0.564MetMet: 0.564 ± 0.008	1.015MetAsn: 1.015 ± 0.011	1.399MetPro: 1.399 ± 0.014	1.326MetGln: 1.326 ± 0.013	1.416MetArg: 1.416 ± 0.012	1.835MetSer: 1.835 ± 0.015	1.125MetThr: 1.125 ± 0.014	1.186MetVal: 1.186 ± 0.011	0.221MetTrp: 0.221 ± 0.005	0.626MetTyr: 0.626 ± 0.007	0.001MetXaa: 0.001 ± 0.0
Asn	3.976AsnAla: 3.976 ± 0.031	0.952AsnCys: 0.952 ± 0.016	2.584AsnAsp: 2.584 ± 0.021	3.199AsnGlu: 3.199 ± 0.021	1.754AsnPhe: 1.754 ± 0.015	3.387AsnGly: 3.387 ± 0.029	1.119AsnHis: 1.119 ± 0.015	2.826AsnIle: 2.826 ± 0.019	2.673AsnLys: 2.673 ± 0.018	4.137AsnLeu: 4.137 ± 0.025	1.213AsnMet: 1.213 ± 0.012	4.046AsnAsn: 4.046 ± 0.045	2.137AsnPro: 2.137 ± 0.028	1.869AsnGln: 1.869 ± 0.015	2.291AsnArg: 2.291 ± 0.018	4.58AsnSer: 4.58 ± 0.036	2.886AsnThr: 2.886 ± 0.019	3.061AsnVal: 3.061 ± 0.021	0.499AsnTrp: 0.499 ± 0.006	1.621AsnTyr: 1.621 ± 0.013	0.001AsnXaa: 0.001 ± 0.0
Pro	4.152ProAla: 4.152 ± 0.046	0.775ProCys: 0.775 ± 0.057	2.394ProAsp: 2.394 ± 0.017	3.237ProGlu: 3.237 ± 0.034	1.556ProPhe: 1.556 ± 0.015	2.747ProGly: 2.747 ± 0.029	1.455ProHis: 1.455 ± 0.015	2.54ProIle: 2.54 ± 0.033	2.999ProLys: 2.999 ± 0.03	4.402ProLeu: 4.402 ± 0.034	1.097ProMet: 1.097 ± 0.011	2.574ProAsn: 2.574 ± 0.026	5.056ProPro: 5.056 ± 0.068	2.931ProGln: 2.931 ± 0.033	2.411ProArg: 2.411 ± 0.019	4.426ProSer: 4.426 ± 0.041	3.952ProThr: 3.952 ± 0.041	3.138ProVal: 3.138 ± 0.03	0.41ProTrp: 0.41 ± 0.006	1.431ProTyr: 1.431 ± 0.013	0.001ProXaa: 0.001 ± 0.0
Gln	3.396GlnAla: 3.396 ± 0.021	0.824GlnCys: 0.824 ± 0.023	1.861GlnAsp: 1.861 ± 0.014	2.86GlnGlu: 2.86 ± 0.025	1.463GlnPhe: 1.463 ± 0.011	1.879GlnGly: 1.879 ± 0.017	2.014GlnHis: 2.014 ± 0.023	2.257GlnIle: 2.257 ± 0.016	2.753GlnLys: 2.753 ± 0.023	5.416GlnLeu: 5.416 ± 0.036	1.246GlnMet: 1.246 ± 0.011	2.18GlnAsn: 2.18 ± 0.016	2.997GlnPro: 2.997 ± 0.035	9.036GlnGln: 9.036 ± 0.15	3.432GlnArg: 3.432 ± 0.025	3.617GlnSer: 3.617 ± 0.026	2.757GlnThr: 2.757 ± 0.021	2.338GlnVal: 2.338 ± 0.016	0.451GlnTrp: 0.451 ± 0.007	1.318GlnTyr: 1.318 ± 0.014	0.002GlnXaa: 0.002 ± 0.0
Arg	3.457ArgAla: 3.457 ± 0.02	1.017ArgCys: 1.017 ± 0.019	2.795ArgAsp: 2.795 ± 0.02	3.54ArgGlu: 3.54 ± 0.031	1.884ArgPhe: 1.884 ± 0.015	2.677ArgGly: 2.677 ± 0.02	1.532ArgHis: 1.532 ± 0.014	2.76ArgIle: 2.76 ± 0.02	3.559ArgLys: 3.559 ± 0.021	4.967ArgLeu: 4.967 ± 0.033	1.182ArgMet: 1.182 ± 0.012	2.782ArgAsn: 2.782 ± 0.018	2.649ArgPro: 2.649 ± 0.03	2.898ArgGln: 2.898 ± 0.024	4.265ArgArg: 4.265 ± 0.029	4.246ArgSer: 4.246 ± 0.034	2.893ArgThr: 2.893 ± 0.017	2.822ArgVal: 2.822 ± 0.02	0.553ArgTrp: 0.553 ± 0.009	1.647ArgTyr: 1.647 ± 0.013	0.002ArgXaa: 0.002 ± 0.0
Ser	6.249SerAla: 6.249 ± 0.043	1.376SerCys: 1.376 ± 0.029	4.098SerAsp: 4.098 ± 0.037	4.496SerGlu: 4.496 ± 0.031	2.487SerPhe: 2.487 ± 0.019	5.46SerGly: 5.46 ± 0.039	1.841SerHis: 1.841 ± 0.017	3.799SerIle: 3.799 ± 0.021	4.229SerLys: 4.229 ± 0.026	6.596SerLeu: 6.596 ± 0.031	1.732SerMet: 1.732 ± 0.015	4.752SerAsn: 4.752 ± 0.037	4.575SerPro: 4.575 ± 0.042	3.425SerGln: 3.425 ± 0.025	3.802SerArg: 3.802 ± 0.028	9.98SerSer: 9.98 ± 0.093	5.866SerThr: 5.866 ± 0.05	4.487SerVal: 4.487 ± 0.025	0.696SerTrp: 0.696 ± 0.008	2.165SerTyr: 2.165 ± 0.023	0.001SerXaa: 0.001 ± 0.0
Thr	5.147ThrAla: 5.147 ± 0.034	1.014ThrCys: 1.014 ± 0.021	2.81ThrAsp: 2.81 ± 0.018	3.452ThrGlu: 3.452 ± 0.028	1.845ThrPhe: 1.845 ± 0.016	3.439ThrGly: 3.439 ± 0.023	1.485ThrHis: 1.485 ± 0.014	3.06ThrIle: 3.06 ± 0.02	3.07ThrLys: 3.07 ± 0.025	5.215ThrLeu: 5.215 ± 0.027	1.224ThrMet: 1.224 ± 0.013	2.949ThrAsn: 2.949 ± 0.018	4.226ThrPro: 4.226 ± 0.042	2.626ThrGln: 2.626 ± 0.021	2.596ThrArg: 2.596 ± 0.019	5.306ThrSer: 5.306 ± 0.035	6.006ThrThr: 6.006 ± 0.087	3.571ThrVal: 3.571 ± 0.03	0.506ThrTrp: 0.506 ± 0.008	1.506ThrTyr: 1.506 ± 0.012	0.0ThrXaa: 0.0 ± 0.0
Val	4.652ValAla: 4.652 ± 0.027	1.156ValCys: 1.156 ± 0.024	3.257ValAsp: 3.257 ± 0.024	3.9ValGlu: 3.9 ± 0.039	1.928ValPhe: 1.928 ± 0.017	3.333ValGly: 3.333 ± 0.02	1.468ValHis: 1.468 ± 0.012	2.88ValIle: 2.88 ± 0.021	3.173ValLys: 3.173 ± 0.03	5.281ValLeu: 5.281 ± 0.03	1.253ValMet: 1.253 ± 0.013	2.686ValAsn: 2.686 ± 0.019	3.248ValPro: 3.248 ± 0.027	2.662ValGln: 2.662 ± 0.018	3.088ValArg: 3.088 ± 0.02	4.217ValSer: 4.217 ± 0.026	3.355ValThr: 3.355 ± 0.028	3.783ValVal: 3.783 ± 0.027	0.547ValTrp: 0.547 ± 0.008	1.613ValTyr: 1.613 ± 0.015	0.001ValXaa: 0.001 ± 0.0
Trp	0.546TrpAla: 0.546 ± 0.008	0.181TrpCys: 0.181 ± 0.004	0.503TrpAsp: 0.503 ± 0.011	0.518TrpGlu: 0.518 ± 0.009	0.367TrpPhe: 0.367 ± 0.006	0.46TrpGly: 0.46 ± 0.007	0.274TrpHis: 0.274 ± 0.006	0.511TrpIle: 0.511 ± 0.008	0.543TrpLys: 0.543 ± 0.009	1.072TrpLeu: 1.072 ± 0.013	0.246TrpMet: 0.246 ± 0.005	0.481TrpAsn: 0.481 ± 0.008	0.368TrpPro: 0.368 ± 0.007	0.495TrpGln: 0.495 ± 0.008	0.646TrpArg: 0.646 ± 0.008	0.699TrpSer: 0.699 ± 0.01	0.568TrpThr: 0.568 ± 0.009	0.519TrpVal: 0.519 ± 0.01	0.157TrpTrp: 0.157 ± 0.004	0.32TrpTyr: 0.32 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.958TyrAla: 1.958 ± 0.018	0.659TyrCys: 0.659 ± 0.011	1.76TyrAsp: 1.76 ± 0.013	1.882TyrGlu: 1.882 ± 0.015	1.211TyrPhe: 1.211 ± 0.013	1.846TyrGly: 1.846 ± 0.016	0.777TyrHis: 0.777 ± 0.009	1.481TyrIle: 1.481 ± 0.014	1.633TyrLys: 1.633 ± 0.014	2.507TyrLeu: 2.507 ± 0.019	0.764TyrMet: 0.764 ± 0.009	1.59TyrAsn: 1.59 ± 0.014	1.234TyrPro: 1.234 ± 0.014	1.316TyrGln: 1.316 ± 0.013	1.632TyrArg: 1.632 ± 0.015	2.092TyrSer: 2.092 ± 0.021	1.625TyrThr: 1.625 ± 0.014	1.748TyrVal: 1.748 ± 0.015	0.329TyrTrp: 0.329 ± 0.006	1.109TyrTyr: 1.109 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.002XaaAsn: 0.002 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.002XaaGln: 0.002 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 17832 proteins (11910080 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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