Amino acid dipepetide frequency for Sulfuritalea hydrogenivorans sk43H

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.851AlaAla: 17.851 ± 0.263	1.387AlaCys: 1.387 ± 0.04	6.643AlaAsp: 6.643 ± 0.085	7.66AlaGlu: 7.66 ± 0.103	3.878AlaPhe: 3.878 ± 0.08	10.72AlaGly: 10.72 ± 0.119	2.356AlaHis: 2.356 ± 0.052	5.947AlaIle: 5.947 ± 0.082	4.62AlaLys: 4.62 ± 0.072	13.416AlaLeu: 13.416 ± 0.184	3.421AlaMet: 3.421 ± 0.051	3.193AlaAsn: 3.193 ± 0.066	5.302AlaPro: 5.302 ± 0.09	4.424AlaGln: 4.424 ± 0.138	8.638AlaArg: 8.638 ± 0.109	5.925AlaSer: 5.925 ± 0.086	6.063AlaThr: 6.063 ± 0.086	8.499AlaVal: 8.499 ± 0.102	1.682AlaTrp: 1.682 ± 0.047	2.364AlaTyr: 2.364 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	1.131CysAla: 1.131 ± 0.029	0.136CysCys: 0.136 ± 0.011	0.582CysAsp: 0.582 ± 0.027	0.546CysGlu: 0.546 ± 0.021	0.37CysPhe: 0.37 ± 0.017	1.048CysGly: 1.048 ± 0.035	0.406CysHis: 0.406 ± 0.031	0.461CysIle: 0.461 ± 0.023	0.304CysLys: 0.304 ± 0.015	0.924CysLeu: 0.924 ± 0.033	0.221CysMet: 0.221 ± 0.015	0.297CysAsn: 0.297 ± 0.017	0.597CysPro: 0.597 ± 0.028	0.271CysGln: 0.271 ± 0.014	0.715CysArg: 0.715 ± 0.029	0.528CysSer: 0.528 ± 0.023	0.472CysThr: 0.472 ± 0.021	0.736CysVal: 0.736 ± 0.024	0.117CysTrp: 0.117 ± 0.009	0.243CysTyr: 0.243 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	6.83AspAla: 6.83 ± 0.085	0.557AspCys: 0.557 ± 0.025	2.885AspAsp: 2.885 ± 0.058	3.391AspGlu: 3.391 ± 0.063	2.283AspPhe: 2.283 ± 0.045	4.506AspGly: 4.506 ± 0.072	1.147AspHis: 1.147 ± 0.033	3.019AspIle: 3.019 ± 0.054	2.079AspLys: 2.079 ± 0.047	5.358AspLeu: 5.358 ± 0.08	1.318AspMet: 1.318 ± 0.032	1.31AspAsn: 1.31 ± 0.036	2.796AspPro: 2.796 ± 0.049	1.699AspGln: 1.699 ± 0.072	3.338AspArg: 3.338 ± 0.066	2.493AspSer: 2.493 ± 0.053	2.584AspThr: 2.584 ± 0.057	3.626AspVal: 3.626 ± 0.062	0.955AspTrp: 0.955 ± 0.029	1.573AspTyr: 1.573 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	7.363GluAla: 7.363 ± 0.103	0.512GluCys: 0.512 ± 0.026	2.505GluAsp: 2.505 ± 0.051	3.117GluGlu: 3.117 ± 0.068	2.308GluPhe: 2.308 ± 0.049	3.776GluGly: 3.776 ± 0.065	1.339GluHis: 1.339 ± 0.031	3.455GluIle: 3.455 ± 0.058	2.843GluLys: 2.843 ± 0.053	6.303GluLeu: 6.303 ± 0.094	1.587GluMet: 1.587 ± 0.037	1.618GluAsn: 1.618 ± 0.04	2.245GluPro: 2.245 ± 0.05	2.458GluGln: 2.458 ± 0.062	4.678GluArg: 4.678 ± 0.085	2.854GluSer: 2.854 ± 0.056	3.073GluThr: 3.073 ± 0.051	4.174GluVal: 4.174 ± 0.059	0.821GluTrp: 0.821 ± 0.026	1.176GluTyr: 1.176 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	4.325PheAla: 4.325 ± 0.071	0.433PheCys: 0.433 ± 0.019	2.556PheAsp: 2.556 ± 0.05	2.12PheGlu: 2.12 ± 0.046	1.499PhePhe: 1.499 ± 0.047	3.392PheGly: 3.392 ± 0.062	0.86PheHis: 0.86 ± 0.028	1.751PheIle: 1.751 ± 0.041	1.285PheLys: 1.285 ± 0.035	3.371PheLeu: 3.371 ± 0.062	0.833PheMet: 0.833 ± 0.028	1.155PheAsn: 1.155 ± 0.033	1.591PhePro: 1.591 ± 0.037	0.987PheGln: 0.987 ± 0.027	2.196PheArg: 2.196 ± 0.045	2.293PheSer: 2.293 ± 0.045	1.716PheThr: 1.716 ± 0.038	2.831PheVal: 2.831 ± 0.054	0.569PheTrp: 0.569 ± 0.027	0.92PheTyr: 0.92 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	8.553GlyAla: 8.553 ± 0.093	0.997GlyCys: 0.997 ± 0.038	4.312GlyAsp: 4.312 ± 0.073	4.893GlyGlu: 4.893 ± 0.081	3.412GlyPhe: 3.412 ± 0.065	6.982GlyGly: 6.982 ± 0.155	1.934GlyHis: 1.934 ± 0.04	4.721GlyIle: 4.721 ± 0.069	4.032GlyLys: 4.032 ± 0.065	8.422GlyLeu: 8.422 ± 0.121	2.526GlyMet: 2.526 ± 0.044	2.521GlyAsn: 2.521 ± 0.068	2.494GlyPro: 2.494 ± 0.049	2.826GlyGln: 2.826 ± 0.049	5.683GlyArg: 5.683 ± 0.078	4.503GlySer: 4.503 ± 0.11	4.251GlyThr: 4.251 ± 0.08	6.015GlyVal: 6.015 ± 0.083	1.267GlyTrp: 1.267 ± 0.037	2.272GlyTyr: 2.272 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.652HisAla: 2.652 ± 0.055	0.31HisCys: 0.31 ± 0.016	1.259HisAsp: 1.259 ± 0.038	1.273HisGlu: 1.273 ± 0.037	0.954HisPhe: 0.954 ± 0.027	2.182HisGly: 2.182 ± 0.047	0.631HisHis: 0.631 ± 0.025	0.989HisIle: 0.989 ± 0.03	0.601HisLys: 0.601 ± 0.023	2.335HisLeu: 2.335 ± 0.048	0.481HisMet: 0.481 ± 0.018	0.508HisAsn: 0.508 ± 0.023	1.448HisPro: 1.448 ± 0.034	0.748HisGln: 0.748 ± 0.027	1.479HisArg: 1.479 ± 0.045	1.016HisSer: 1.016 ± 0.031	0.859HisThr: 0.859 ± 0.029	1.51HisVal: 1.51 ± 0.034	0.358HisTrp: 0.358 ± 0.018	0.674HisTyr: 0.674 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.862IleAla: 6.862 ± 0.116	0.496IleCys: 0.496 ± 0.021	3.397IleAsp: 3.397 ± 0.054	3.665IleGlu: 3.665 ± 0.064	1.616IlePhe: 1.616 ± 0.043	4.715IleGly: 4.715 ± 0.064	1.047IleHis: 1.047 ± 0.028	1.997IleIle: 1.997 ± 0.042	1.828IleLys: 1.828 ± 0.043	4.257IleLeu: 4.257 ± 0.063	0.935IleMet: 0.935 ± 0.035	1.628IleAsn: 1.628 ± 0.036	2.406IlePro: 2.406 ± 0.043	1.376IleGln: 1.376 ± 0.045	3.113IleArg: 3.113 ± 0.062	2.783IleSer: 2.783 ± 0.054	2.641IleThr: 2.641 ± 0.053	3.84IleVal: 3.84 ± 0.058	0.533IleTrp: 0.533 ± 0.025	1.16IleTyr: 1.16 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.573LysAla: 4.573 ± 0.074	0.291LysCys: 0.291 ± 0.018	2.012LysAsp: 2.012 ± 0.046	2.079LysGlu: 2.079 ± 0.048	1.195LysPhe: 1.195 ± 0.038	2.902LysGly: 2.902 ± 0.061	0.805LysHis: 0.805 ± 0.027	1.993LysIle: 1.993 ± 0.044	1.97LysLys: 1.97 ± 0.057	4.285LysLeu: 4.285 ± 0.07	1.05LysMet: 1.05 ± 0.033	1.205LysAsn: 1.205 ± 0.034	2.452LysPro: 2.452 ± 0.053	1.447LysGln: 1.447 ± 0.039	2.626LysArg: 2.626 ± 0.05	2.144LysSer: 2.144 ± 0.043	2.09LysThr: 2.09 ± 0.046	2.825LysVal: 2.825 ± 0.058	0.412LysTrp: 0.412 ± 0.021	0.815LysTyr: 0.815 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	14.868LeuAla: 14.868 ± 0.159	1.02LeuCys: 1.02 ± 0.031	6.056LeuAsp: 6.056 ± 0.071	5.702LeuGlu: 5.702 ± 0.078	3.632LeuPhe: 3.632 ± 0.071	8.489LeuGly: 8.489 ± 0.097	2.235LeuHis: 2.235 ± 0.045	4.936LeuIle: 4.936 ± 0.071	4.324LeuLys: 4.324 ± 0.06	11.413LeuLeu: 11.413 ± 0.142	2.53LeuMet: 2.53 ± 0.046	2.705LeuAsn: 2.705 ± 0.061	5.936LeuPro: 5.936 ± 0.088	3.251LeuGln: 3.251 ± 0.049	7.307LeuArg: 7.307 ± 0.093	5.809LeuSer: 5.809 ± 0.119	5.574LeuThr: 5.574 ± 0.228	7.4LeuVal: 7.4 ± 0.091	1.291LeuTrp: 1.291 ± 0.035	2.059LeuTyr: 2.059 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	3.052MetAla: 3.052 ± 0.058	0.166MetCys: 0.166 ± 0.012	1.2MetAsp: 1.2 ± 0.036	1.311MetGlu: 1.311 ± 0.036	0.766MetPhe: 0.766 ± 0.03	1.82MetGly: 1.82 ± 0.044	0.565MetHis: 0.565 ± 0.022	1.262MetIle: 1.262 ± 0.035	1.286MetLys: 1.286 ± 0.034	2.74MetLeu: 2.74 ± 0.052	0.66MetMet: 0.66 ± 0.028	0.987MetAsn: 0.987 ± 0.027	1.401MetPro: 1.401 ± 0.039	1.033MetGln: 1.033 ± 0.033	1.751MetArg: 1.751 ± 0.04	1.575MetSer: 1.575 ± 0.038	1.519MetThr: 1.519 ± 0.034	1.715MetVal: 1.715 ± 0.04	0.223MetTrp: 0.223 ± 0.015	0.405MetTyr: 0.405 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.186AsnAla: 3.186 ± 0.06	0.328AsnCys: 0.328 ± 0.015	1.473AsnAsp: 1.473 ± 0.049	1.457AsnGlu: 1.457 ± 0.035	1.087AsnPhe: 1.087 ± 0.028	2.307AsnGly: 2.307 ± 0.055	0.539AsnHis: 0.539 ± 0.019	1.395AsnIle: 1.395 ± 0.036	0.966AsnLys: 0.966 ± 0.034	2.974AsnLeu: 2.974 ± 0.049	0.678AsnMet: 0.678 ± 0.027	0.814AsnAsn: 0.814 ± 0.035	2.006AsnPro: 2.006 ± 0.045	0.881AsnGln: 0.881 ± 0.028	1.93AsnArg: 1.93 ± 0.048	1.338AsnSer: 1.338 ± 0.041	1.364AsnThr: 1.364 ± 0.038	1.983AsnVal: 1.983 ± 0.044	0.414AsnTrp: 0.414 ± 0.02	0.731AsnTyr: 0.731 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	6.465ProAla: 6.465 ± 0.099	0.41ProCys: 0.41 ± 0.02	2.991ProAsp: 2.991 ± 0.053	3.397ProGlu: 3.397 ± 0.062	1.673ProPhe: 1.673 ± 0.04	4.26ProGly: 4.26 ± 0.063	1.03ProHis: 1.03 ± 0.032	1.983ProIle: 1.983 ± 0.043	1.791ProLys: 1.791 ± 0.044	4.993ProLeu: 4.993 ± 0.074	1.188ProMet: 1.188 ± 0.032	1.308ProAsn: 1.308 ± 0.041	2.57ProPro: 2.57 ± 0.056	1.815ProGln: 1.815 ± 0.039	2.785ProArg: 2.785 ± 0.053	2.151ProSer: 2.151 ± 0.047	2.325ProThr: 2.325 ± 0.045	3.97ProVal: 3.97 ± 0.066	0.677ProTrp: 0.677 ± 0.024	1.104ProTyr: 1.104 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.407GlnAla: 4.407 ± 0.101	0.281GlnCys: 0.281 ± 0.014	1.441GlnAsp: 1.441 ± 0.036	1.755GlnGlu: 1.755 ± 0.039	1.154GlnPhe: 1.154 ± 0.035	2.572GlnGly: 2.572 ± 0.042	0.822GlnHis: 0.822 ± 0.028	1.852GlnIle: 1.852 ± 0.098	1.392GlnLys: 1.392 ± 0.037	3.803GlnLeu: 3.803 ± 0.087	0.994GlnMet: 0.994 ± 0.036	0.914GlnAsn: 0.914 ± 0.032	1.723GlnPro: 1.723 ± 0.041	1.513GlnGln: 1.513 ± 0.045	2.885GlnArg: 2.885 ± 0.056	1.759GlnSer: 1.759 ± 0.042	1.704GlnThr: 1.704 ± 0.042	2.53GlnVal: 2.53 ± 0.076	0.506GlnTrp: 0.506 ± 0.021	0.686GlnTyr: 0.686 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	6.895ArgAla: 6.895 ± 0.092	0.596ArgCys: 0.596 ± 0.021	3.798ArgAsp: 3.798 ± 0.068	4.619ArgGlu: 4.619 ± 0.066	2.858ArgPhe: 2.858 ± 0.048	4.533ArgGly: 4.533 ± 0.065	1.973ArgHis: 1.973 ± 0.045	4.113ArgIle: 4.113 ± 0.064	2.531ArgLys: 2.531 ± 0.051	7.923ArgLeu: 7.923 ± 0.106	1.914ArgMet: 1.914 ± 0.033	2.081ArgAsn: 2.081 ± 0.044	2.905ArgPro: 2.905 ± 0.054	2.893ArgGln: 2.893 ± 0.056	5.179ArgArg: 5.179 ± 0.084	3.187ArgSer: 3.187 ± 0.051	2.917ArgThr: 2.917 ± 0.051	4.813ArgVal: 4.813 ± 0.077	1.022ArgTrp: 1.022 ± 0.03	1.911ArgTyr: 1.911 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	5.876SerAla: 5.876 ± 0.079	0.551SerCys: 0.551 ± 0.024	2.504SerAsp: 2.504 ± 0.053	2.575SerGlu: 2.575 ± 0.048	2.158SerPhe: 2.158 ± 0.042	5.438SerGly: 5.438 ± 0.109	1.219SerHis: 1.219 ± 0.03	2.623SerIle: 2.623 ± 0.048	1.796SerLys: 1.796 ± 0.046	5.734SerLeu: 5.734 ± 0.076	1.32SerMet: 1.32 ± 0.036	1.356SerAsn: 1.356 ± 0.038	2.551SerPro: 2.551 ± 0.054	1.676SerGln: 1.676 ± 0.04	3.499SerArg: 3.499 ± 0.054	2.962SerSer: 2.962 ± 0.065	2.629SerThr: 2.629 ± 0.104	3.596SerVal: 3.596 ± 0.061	0.656SerTrp: 0.656 ± 0.022	1.205SerTyr: 1.205 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.987ThrAla: 5.987 ± 0.168	0.435ThrCys: 0.435 ± 0.021	2.425ThrAsp: 2.425 ± 0.059	2.586ThrGlu: 2.586 ± 0.047	1.563ThrPhe: 1.563 ± 0.045	4.679ThrGly: 4.679 ± 0.075	1.099ThrHis: 1.099 ± 0.031	2.331ThrIle: 2.331 ± 0.05	1.447ThrLys: 1.447 ± 0.038	6.092ThrLeu: 6.092 ± 0.094	1.04ThrMet: 1.04 ± 0.035	1.233ThrAsn: 1.233 ± 0.044	3.264ThrPro: 3.264 ± 0.055	1.814ThrGln: 1.814 ± 0.111	3.248ThrArg: 3.248 ± 0.06	2.505ThrSer: 2.505 ± 0.072	2.912ThrThr: 2.912 ± 0.244	3.985ThrVal: 3.985 ± 0.067	0.584ThrTrp: 0.584 ± 0.022	1.061ThrTyr: 1.061 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	9.403ValAla: 9.403 ± 0.114	0.757ValCys: 0.757 ± 0.026	3.939ValAsp: 3.939 ± 0.061	4.332ValGlu: 4.332 ± 0.07	2.752ValPhe: 2.752 ± 0.054	5.562ValGly: 5.562 ± 0.076	1.351ValHis: 1.351 ± 0.032	3.913ValIle: 3.913 ± 0.064	2.825ValLys: 2.825 ± 0.051	7.594ValLeu: 7.594 ± 0.091	1.934ValMet: 1.934 ± 0.04	1.922ValAsn: 1.922 ± 0.047	3.427ValPro: 3.427 ± 0.073	2.028ValGln: 2.028 ± 0.051	4.598ValArg: 4.598 ± 0.066	4.087ValSer: 4.087 ± 0.052	3.928ValThr: 3.928 ± 0.065	5.847ValVal: 5.847 ± 0.094	0.88ValTrp: 0.88 ± 0.031	1.343ValTyr: 1.343 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.164TrpAla: 1.164 ± 0.037	0.155TrpCys: 0.155 ± 0.012	0.592TrpAsp: 0.592 ± 0.024	0.616TrpGlu: 0.616 ± 0.023	0.565TrpPhe: 0.565 ± 0.024	0.847TrpGly: 0.847 ± 0.029	0.389TrpHis: 0.389 ± 0.02	0.683TrpIle: 0.683 ± 0.024	0.536TrpLys: 0.536 ± 0.022	2.057TrpLeu: 2.057 ± 0.055	0.341TrpMet: 0.341 ± 0.018	0.496TrpAsn: 0.496 ± 0.022	0.611TrpPro: 0.611 ± 0.027	0.677TrpGln: 0.677 ± 0.023	1.134TrpArg: 1.134 ± 0.033	0.692TrpSer: 0.692 ± 0.023	0.575TrpThr: 0.575 ± 0.023	0.898TrpVal: 0.898 ± 0.026	0.255TrpTrp: 0.255 ± 0.016	0.314TrpTyr: 0.314 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.544TyrAla: 2.544 ± 0.05	0.285TyrCys: 0.285 ± 0.015	1.18TyrAsp: 1.18 ± 0.035	1.11TyrGlu: 1.11 ± 0.03	0.961TyrPhe: 0.961 ± 0.029	1.888TyrGly: 1.888 ± 0.048	0.52TyrHis: 0.52 ± 0.017	0.872TyrIle: 0.872 ± 0.029	0.711TyrLys: 0.711 ± 0.026	2.544TyrLeu: 2.544 ± 0.052	0.466TyrMet: 0.466 ± 0.016	0.602TyrAsn: 0.602 ± 0.022	1.162TyrPro: 1.162 ± 0.037	0.875TyrGln: 0.875 ± 0.03	1.88TyrArg: 1.88 ± 0.044	1.32TyrSer: 1.32 ± 0.036	1.094TyrThr: 1.094 ± 0.034	1.626TyrVal: 1.626 ± 0.041	0.374TyrTrp: 0.374 ± 0.019	0.605TyrTyr: 0.605 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3578 proteins (1166199 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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