Amino acid dipepetide frequency for Tomato leaf curl Palampur virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.359AlaAla: 3.359 ± 1.352
1.68AlaCys: 1.68 ± 0.819
2.24AlaAsp: 2.24 ± 0.804
2.8AlaGlu: 2.8 ± 1.125
1.68AlaPhe: 1.68 ± 0.855
1.12AlaGly: 1.12 ± 0.538
0.56AlaHis: 0.56 ± 0.459
2.24AlaIle: 2.24 ± 0.964
3.359AlaLys: 3.359 ± 1.067
5.039AlaLeu: 5.039 ± 2.211
0.56AlaMet: 0.56 ± 0.512
1.12AlaAsn: 1.12 ± 0.61
3.919AlaPro: 3.919 ± 1.671
2.24AlaGln: 2.24 ± 0.914
4.479AlaArg: 4.479 ± 1.702
5.039AlaSer: 5.039 ± 0.838
2.8AlaThr: 2.8 ± 1.521
3.359AlaVal: 3.359 ± 0.892
0.56AlaTrp: 0.56 ± 0.459
1.12AlaTyr: 1.12 ± 0.657
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.56CysCys: 0.56 ± 0.691
0.0CysAsp: 0.0 ± 0.0
1.68CysGlu: 1.68 ± 0.819
1.12CysPhe: 1.12 ± 0.702
2.8CysGly: 2.8 ± 1.494
0.56CysHis: 0.56 ± 0.572
2.24CysIle: 2.24 ± 1.019
1.12CysLys: 1.12 ± 0.594
1.12CysLeu: 1.12 ± 0.702
1.12CysMet: 1.12 ± 0.811
1.68CysAsn: 1.68 ± 1.071
1.68CysPro: 1.68 ± 2.074
0.0CysGln: 0.0 ± 0.0
1.68CysArg: 1.68 ± 0.625
2.24CysSer: 2.24 ± 1.095
1.68CysThr: 1.68 ± 0.819
0.56CysVal: 0.56 ± 0.461
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.8AspAla: 2.8 ± 1.327
0.0AspCys: 0.0 ± 0.0
1.12AspAsp: 1.12 ± 0.638
2.24AspGlu: 2.24 ± 0.749
1.12AspPhe: 1.12 ± 0.538
3.919AspGly: 3.919 ± 1.478
1.68AspHis: 1.68 ± 1.221
3.919AspIle: 3.919 ± 1.219
1.12AspLys: 1.12 ± 0.537
5.039AspLeu: 5.039 ± 1.567
1.12AspMet: 1.12 ± 0.729
2.24AspAsn: 2.24 ± 0.946
1.68AspPro: 1.68 ± 0.8
0.56AspGln: 0.56 ± 0.526
3.919AspArg: 3.919 ± 0.952
4.479AspSer: 4.479 ± 1.203
1.12AspThr: 1.12 ± 0.811
7.279AspVal: 7.279 ± 1.766
1.68AspTrp: 1.68 ± 0.993
0.56AspTyr: 0.56 ± 0.459
0.0AspXaa: 0.0 ± 0.0
Glu
1.68GluAla: 1.68 ± 0.76
0.0GluCys: 0.0 ± 0.0
1.68GluAsp: 1.68 ± 0.85
5.599GluGlu: 5.599 ± 2.317
3.359GluPhe: 3.359 ± 1.653
3.359GluGly: 3.359 ± 1.465
1.12GluHis: 1.12 ± 0.61
3.919GluIle: 3.919 ± 2.002
1.68GluLys: 1.68 ± 0.841
3.359GluLeu: 3.359 ± 1.445
0.56GluMet: 0.56 ± 0.526
3.359GluAsn: 3.359 ± 1.3
2.24GluPro: 2.24 ± 0.993
2.24GluGln: 2.24 ± 1.053
1.68GluArg: 1.68 ± 0.816
4.479GluSer: 4.479 ± 1.827
4.479GluThr: 4.479 ± 1.43
2.24GluVal: 2.24 ± 0.61
1.68GluTrp: 1.68 ± 0.788
2.8GluTyr: 2.8 ± 1.605
0.0GluXaa: 0.0 ± 0.0
Phe
1.12PheAla: 1.12 ± 0.737
1.68PheCys: 1.68 ± 0.622
2.24PheAsp: 2.24 ± 1.188
2.24PheGlu: 2.24 ± 0.761
1.68PhePhe: 1.68 ± 0.596
1.68PheGly: 1.68 ± 1.073
1.12PheHis: 1.12 ± 0.918
1.68PheIle: 1.68 ± 0.956
2.24PheLys: 2.24 ± 1.129
4.479PheLeu: 4.479 ± 1.391
1.12PheMet: 1.12 ± 0.8
2.24PheAsn: 2.24 ± 0.897
3.359PhePro: 3.359 ± 1.08
2.8PheGln: 2.8 ± 1.311
3.359PheArg: 3.359 ± 1.221
2.24PheSer: 2.24 ± 0.929
2.24PheThr: 2.24 ± 0.794
1.12PheVal: 1.12 ± 0.737
1.12PheTrp: 1.12 ± 0.673
1.12PheTyr: 1.12 ± 0.923
0.0PheXaa: 0.0 ± 0.0
Gly
2.8GlyAla: 2.8 ± 1.078
1.12GlyCys: 1.12 ± 0.757
2.24GlyAsp: 2.24 ± 0.94
2.8GlyGlu: 2.8 ± 1.466
1.12GlyPhe: 1.12 ± 0.776
2.8GlyGly: 2.8 ± 0.736
2.8GlyHis: 2.8 ± 1.471
1.68GlyIle: 1.68 ± 0.749
5.039GlyLys: 5.039 ± 1.804
7.839GlyLeu: 7.839 ± 1.586
1.12GlyMet: 1.12 ± 0.81
1.12GlyAsn: 1.12 ± 0.61
3.919GlyPro: 3.919 ± 1.464
1.12GlyGln: 1.12 ± 0.816
3.359GlyArg: 3.359 ± 1.088
6.159GlySer: 6.159 ± 1.994
3.359GlyThr: 3.359 ± 2.146
3.359GlyVal: 3.359 ± 1.353
0.0GlyTrp: 0.0 ± 0.0
1.12GlyTyr: 1.12 ± 0.811
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.56HisCys: 0.56 ± 0.572
2.8HisAsp: 2.8 ± 1.262
2.24HisGlu: 2.24 ± 1.462
2.24HisPhe: 2.24 ± 1.021
1.68HisGly: 1.68 ± 1.067
1.68HisHis: 1.68 ± 1.183
3.359HisIle: 3.359 ± 1.057
1.12HisLys: 1.12 ± 0.834
1.68HisLeu: 1.68 ± 1.028
0.0HisMet: 0.0 ± 0.0
1.68HisAsn: 1.68 ± 0.994
3.359HisPro: 3.359 ± 1.631
0.56HisGln: 0.56 ± 0.512
2.8HisArg: 2.8 ± 1.308
3.919HisSer: 3.919 ± 2.189
3.359HisThr: 3.359 ± 1.555
2.8HisVal: 2.8 ± 1.012
0.0HisTrp: 0.0 ± 0.0
1.68HisTyr: 1.68 ± 0.774
0.0HisXaa: 0.0 ± 0.0
Ile
0.56IleAla: 0.56 ± 0.521
1.12IleCys: 1.12 ± 0.537
3.359IleAsp: 3.359 ± 1.915
2.8IleGlu: 2.8 ± 1.545
1.68IlePhe: 1.68 ± 0.85
3.919IleGly: 3.919 ± 1.263
2.8IleHis: 2.8 ± 1.088
1.68IleIle: 1.68 ± 0.816
3.919IleLys: 3.919 ± 0.834
4.479IleLeu: 4.479 ± 1.833
0.0IleMet: 0.0 ± 0.0
2.8IleAsn: 2.8 ± 1.034
3.359IlePro: 3.359 ± 1.165
1.68IleGln: 1.68 ± 0.994
6.159IleArg: 6.159 ± 1.241
5.039IleSer: 5.039 ± 1.762
3.919IleThr: 3.919 ± 1.595
2.24IleVal: 2.24 ± 0.714
1.68IleTrp: 1.68 ± 1.217
2.24IleTyr: 2.24 ± 1.273
0.0IleXaa: 0.0 ± 0.0
Lys
1.68LysAla: 1.68 ± 1.11
1.68LysCys: 1.68 ± 0.77
1.68LysAsp: 1.68 ± 0.982
5.599LysGlu: 5.599 ± 1.908
2.24LysPhe: 2.24 ± 1.075
2.8LysGly: 2.8 ± 1.441
2.8LysHis: 2.8 ± 1.012
5.599LysIle: 5.599 ± 1.287
3.919LysLys: 3.919 ± 2.177
3.359LysLeu: 3.359 ± 1.628
0.0LysMet: 0.0 ± 0.0
5.039LysAsn: 5.039 ± 1.717
1.68LysPro: 1.68 ± 0.596
1.68LysGln: 1.68 ± 0.625
2.24LysArg: 2.24 ± 1.474
4.479LysSer: 4.479 ± 1.235
5.599LysThr: 5.599 ± 0.883
2.24LysVal: 2.24 ± 0.91
0.56LysTrp: 0.56 ± 0.461
2.24LysTyr: 2.24 ± 0.874
0.0LysXaa: 0.0 ± 0.0
Leu
1.68LeuAla: 1.68 ± 0.841
1.68LeuCys: 1.68 ± 0.95
5.039LeuAsp: 5.039 ± 1.203
3.359LeuGlu: 3.359 ± 1.805
0.56LeuPhe: 0.56 ± 0.526
5.039LeuGly: 5.039 ± 0.979
4.479LeuHis: 4.479 ± 1.595
2.8LeuIle: 2.8 ± 1.027
8.399LeuLys: 8.399 ± 1.636
0.56LeuLeu: 0.56 ± 0.691
1.68LeuMet: 1.68 ± 0.76
5.599LeuAsn: 5.599 ± 1.488
2.8LeuPro: 2.8 ± 1.463
2.8LeuGln: 2.8 ± 0.84
6.159LeuArg: 6.159 ± 2.099
4.479LeuSer: 4.479 ± 1.951
6.719LeuThr: 6.719 ± 1.904
4.479LeuVal: 4.479 ± 1.239
0.56LeuTrp: 0.56 ± 0.512
3.359LeuTyr: 3.359 ± 1.454
0.0LeuXaa: 0.0 ± 0.0
Met
1.68MetAla: 1.68 ± 0.588
1.12MetCys: 1.12 ± 0.688
0.56MetAsp: 0.56 ± 0.461
0.0MetGlu: 0.0 ± 0.0
2.24MetPhe: 2.24 ± 1.019
2.24MetGly: 2.24 ± 1.12
1.12MetHis: 1.12 ± 0.688
1.12MetIle: 1.12 ± 0.657
1.12MetLys: 1.12 ± 0.673
1.68MetLeu: 1.68 ± 0.924
1.12MetMet: 1.12 ± 0.537
0.56MetAsn: 0.56 ± 0.461
0.0MetPro: 0.0 ± 0.0
1.12MetGln: 1.12 ± 0.673
0.56MetArg: 0.56 ± 0.521
1.68MetSer: 1.68 ± 1.0
1.12MetThr: 1.12 ± 0.537
0.56MetVal: 0.56 ± 0.461
1.12MetTrp: 1.12 ± 0.73
0.56MetTyr: 0.56 ± 0.461
0.0MetXaa: 0.0 ± 0.0
Asn
5.039AsnAla: 5.039 ± 1.068
2.24AsnCys: 2.24 ± 1.082
2.8AsnAsp: 2.8 ± 1.684
1.12AsnGlu: 1.12 ± 0.538
1.68AsnPhe: 1.68 ± 0.92
0.56AsnGly: 0.56 ± 0.526
2.24AsnHis: 2.24 ± 1.485
2.8AsnIle: 2.8 ± 1.207
1.12AsnLys: 1.12 ± 0.918
5.039AsnLeu: 5.039 ± 1.754
2.24AsnMet: 2.24 ± 1.432
2.8AsnAsn: 2.8 ± 1.03
2.8AsnPro: 2.8 ± 0.838
1.68AsnGln: 1.68 ± 0.987
3.919AsnArg: 3.919 ± 0.967
2.24AsnSer: 2.24 ± 1.078
5.039AsnThr: 5.039 ± 1.169
4.479AsnVal: 4.479 ± 1.272
0.0AsnTrp: 0.0 ± 0.0
2.8AsnTyr: 2.8 ± 0.851
0.0AsnXaa: 0.0 ± 0.0
Pro
1.12ProAla: 1.12 ± 0.923
2.24ProCys: 2.24 ± 1.031
2.24ProAsp: 2.24 ± 1.621
2.24ProGlu: 2.24 ± 1.462
2.24ProPhe: 2.24 ± 0.887
2.24ProGly: 2.24 ± 1.159
2.8ProHis: 2.8 ± 1.214
3.359ProIle: 3.359 ± 0.957
3.359ProLys: 3.359 ± 0.94
2.8ProLeu: 2.8 ± 0.794
1.68ProMet: 1.68 ± 0.781
2.24ProAsn: 2.24 ± 0.824
1.68ProPro: 1.68 ± 0.982
4.479ProGln: 4.479 ± 1.303
3.919ProArg: 3.919 ± 1.165
6.719ProSer: 6.719 ± 1.401
2.24ProThr: 2.24 ± 1.377
3.359ProVal: 3.359 ± 1.783
1.12ProTrp: 1.12 ± 0.673
2.8ProTyr: 2.8 ± 1.028
0.0ProXaa: 0.0 ± 0.0
Gln
2.24GlnAla: 2.24 ± 0.948
1.68GlnCys: 1.68 ± 0.774
1.12GlnAsp: 1.12 ± 0.636
2.24GlnGlu: 2.24 ± 0.986
1.68GlnPhe: 1.68 ± 0.994
1.68GlnGly: 1.68 ± 0.747
0.56GlnHis: 0.56 ± 0.728
1.68GlnIle: 1.68 ± 1.115
0.56GlnLys: 0.56 ± 0.521
1.12GlnLeu: 1.12 ± 0.638
0.56GlnMet: 0.56 ± 0.728
2.24GlnAsn: 2.24 ± 1.053
2.8GlnPro: 2.8 ± 1.507
1.68GlnGln: 1.68 ± 0.588
1.68GlnArg: 1.68 ± 0.879
3.919GlnSer: 3.919 ± 0.79
2.8GlnThr: 2.8 ± 0.846
3.359GlnVal: 3.359 ± 0.983
0.56GlnTrp: 0.56 ± 0.459
0.56GlnTyr: 0.56 ± 0.526
0.0GlnXaa: 0.0 ± 0.0
Arg
4.479ArgAla: 4.479 ± 2.062
2.24ArgCys: 2.24 ± 0.82
5.039ArgAsp: 5.039 ± 1.538
4.479ArgGlu: 4.479 ± 1.44
5.039ArgPhe: 5.039 ± 1.521
2.8ArgGly: 2.8 ± 0.989
3.359ArgHis: 3.359 ± 1.498
3.919ArgIle: 3.919 ± 1.365
2.24ArgLys: 2.24 ± 1.18
3.359ArgLeu: 3.359 ± 1.347
1.12ArgMet: 1.12 ± 0.657
2.8ArgAsn: 2.8 ± 1.416
5.599ArgPro: 5.599 ± 1.513
1.12ArgGln: 1.12 ± 1.071
6.159ArgArg: 6.159 ± 2.536
7.839ArgSer: 7.839 ± 1.66
3.359ArgThr: 3.359 ± 1.245
7.279ArgVal: 7.279 ± 1.622
0.0ArgTrp: 0.0 ± 0.0
2.24ArgTyr: 2.24 ± 1.194
0.0ArgXaa: 0.0 ± 0.0
Ser
6.719SerAla: 6.719 ± 2.13
1.12SerCys: 1.12 ± 0.867
3.359SerAsp: 3.359 ± 1.074
2.24SerGlu: 2.24 ± 1.19
2.24SerPhe: 2.24 ± 0.761
3.359SerGly: 3.359 ± 0.991
0.56SerHis: 0.56 ± 0.461
4.479SerIle: 4.479 ± 1.643
6.159SerLys: 6.159 ± 1.595
4.479SerLeu: 4.479 ± 1.26
1.68SerMet: 1.68 ± 0.867
5.039SerAsn: 5.039 ± 1.142
4.479SerPro: 4.479 ± 1.229
3.919SerGln: 3.919 ± 1.539
7.839SerArg: 7.839 ± 1.728
11.198SerSer: 11.198 ± 3.044
6.719SerThr: 6.719 ± 2.192
6.719SerVal: 6.719 ± 1.954
1.12SerTrp: 1.12 ± 0.625
2.8SerTyr: 2.8 ± 1.374
0.0SerXaa: 0.0 ± 0.0
Thr
3.359ThrAla: 3.359 ± 1.133
0.0ThrCys: 0.0 ± 0.0
2.24ThrAsp: 2.24 ± 0.931
3.359ThrGlu: 3.359 ± 1.306
3.359ThrPhe: 3.359 ± 1.87
7.279ThrGly: 7.279 ± 2.087
3.359ThrHis: 3.359 ± 1.633
2.8ThrIle: 2.8 ± 1.108
3.919ThrLys: 3.919 ± 1.15
3.359ThrLeu: 3.359 ± 0.792
1.12ThrMet: 1.12 ± 0.537
5.039ThrAsn: 5.039 ± 1.013
3.359ThrPro: 3.359 ± 1.011
1.12ThrGln: 1.12 ± 0.724
5.039ThrArg: 5.039 ± 1.265
3.359ThrSer: 3.359 ± 0.997
1.68ThrThr: 1.68 ± 1.175
3.919ThrVal: 3.919 ± 1.381
1.68ThrTrp: 1.68 ± 1.065
4.479ThrTyr: 4.479 ± 1.281
0.0ThrXaa: 0.0 ± 0.0
Val
2.8ValAla: 2.8 ± 0.889
0.56ValCys: 0.56 ± 0.691
5.039ValAsp: 5.039 ± 0.961
3.919ValGlu: 3.919 ± 2.53
3.359ValPhe: 3.359 ± 1.378
3.359ValGly: 3.359 ± 1.543
2.8ValHis: 2.8 ± 1.621
2.24ValIle: 2.24 ± 0.727
5.039ValLys: 5.039 ± 1.684
7.839ValLeu: 7.839 ± 2.081
1.68ValMet: 1.68 ± 0.849
2.8ValAsn: 2.8 ± 1.146
4.479ValPro: 4.479 ± 0.893
2.8ValGln: 2.8 ± 0.933
5.039ValArg: 5.039 ± 2.225
2.24ValSer: 2.24 ± 0.992
3.359ValThr: 3.359 ± 1.419
6.159ValVal: 6.159 ± 2.153
1.12ValTrp: 1.12 ± 0.724
3.919ValTyr: 3.919 ± 1.656
0.0ValXaa: 0.0 ± 0.0
Trp
3.359TrpAla: 3.359 ± 0.967
0.0TrpCys: 0.0 ± 0.0
1.12TrpAsp: 1.12 ± 0.834
0.0TrpGlu: 0.0 ± 0.0
0.56TrpPhe: 0.56 ± 0.512
0.56TrpGly: 0.56 ± 0.459
0.56TrpHis: 0.56 ± 0.461
0.0TrpIle: 0.0 ± 0.0
0.56TrpLys: 0.56 ± 0.526
1.68TrpLeu: 1.68 ± 1.361
0.56TrpMet: 0.56 ± 0.461
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.56TrpGln: 0.56 ± 0.459
1.68TrpArg: 1.68 ± 0.829
0.56TrpSer: 0.56 ± 0.521
0.56TrpThr: 0.56 ± 0.544
1.68TrpVal: 1.68 ± 0.588
0.0TrpTrp: 0.0 ± 0.0
0.56TrpTyr: 0.56 ± 0.459
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.8TyrAla: 2.8 ± 1.236
0.56TyrCys: 0.56 ± 0.691
1.68TyrAsp: 1.68 ± 0.924
0.56TyrGlu: 0.56 ± 0.461
1.68TyrPhe: 1.68 ± 0.785
1.68TyrGly: 1.68 ± 0.747
0.56TyrHis: 0.56 ± 0.544
3.919TyrIle: 3.919 ± 1.255
1.12TyrLys: 1.12 ± 0.638
3.919TyrLeu: 3.919 ± 1.455
1.68TyrMet: 1.68 ± 0.792
2.24TyrAsn: 2.24 ± 0.68
1.68TyrPro: 1.68 ± 0.96
0.56TyrGln: 0.56 ± 0.461
2.8TyrArg: 2.8 ± 1.038
3.919TyrSer: 3.919 ± 1.378
1.68TyrThr: 1.68 ± 1.579
3.919TyrVal: 3.919 ± 1.353
0.0TyrTrp: 0.0 ± 0.0
1.68TyrTyr: 1.68 ± 0.765
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (1787 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski