Amino acid dipepetide frequency for Dermatophilus congolensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.03AlaAla: 17.03 ± 0.236	1.093AlaCys: 1.093 ± 0.036	6.33AlaAsp: 6.33 ± 0.099	6.764AlaGlu: 6.764 ± 0.118	3.403AlaPhe: 3.403 ± 0.07	10.617AlaGly: 10.617 ± 0.133	3.074AlaHis: 3.074 ± 0.074	5.453AlaIle: 5.453 ± 0.108	3.073AlaLys: 3.073 ± 0.086	12.642AlaLeu: 12.642 ± 0.148	2.677AlaMet: 2.677 ± 0.063	2.72AlaAsn: 2.72 ± 0.068	5.512AlaPro: 5.512 ± 0.101	4.393AlaGln: 4.393 ± 0.081	7.749AlaArg: 7.749 ± 0.117	6.469AlaSer: 6.469 ± 0.105	8.24AlaThr: 8.24 ± 0.131	9.92AlaVal: 9.92 ± 0.156	1.7AlaTrp: 1.7 ± 0.042	2.28AlaTyr: 2.28 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	1.082CysAla: 1.082 ± 0.04	0.128CysCys: 0.128 ± 0.014	0.427CysAsp: 0.427 ± 0.025	0.428CysGlu: 0.428 ± 0.025	0.226CysPhe: 0.226 ± 0.018	1.004CysGly: 1.004 ± 0.045	0.205CysHis: 0.205 ± 0.015	0.294CysIle: 0.294 ± 0.021	0.132CysLys: 0.132 ± 0.015	0.753CysLeu: 0.753 ± 0.036	0.146CysMet: 0.146 ± 0.014	0.179CysAsn: 0.179 ± 0.016	0.471CysPro: 0.471 ± 0.031	0.234CysGln: 0.234 ± 0.017	0.505CysArg: 0.505 ± 0.025	0.519CysSer: 0.519 ± 0.026	0.519CysThr: 0.519 ± 0.027	0.793CysVal: 0.793 ± 0.031	0.119CysTrp: 0.119 ± 0.012	0.13CysTyr: 0.13 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.388AspAla: 6.388 ± 0.106	0.395AspCys: 0.395 ± 0.024	2.842AspAsp: 2.842 ± 0.071	3.789AspGlu: 3.789 ± 0.08	1.55AspPhe: 1.55 ± 0.049	4.582AspGly: 4.582 ± 0.087	1.311AspHis: 1.311 ± 0.042	2.897AspIle: 2.897 ± 0.061	1.413AspLys: 1.413 ± 0.049	5.751AspLeu: 5.751 ± 0.092	0.975AspMet: 0.975 ± 0.037	1.375AspAsn: 1.375 ± 0.043	3.856AspPro: 3.856 ± 0.071	1.518AspGln: 1.518 ± 0.041	3.476AspArg: 3.476 ± 0.07	2.736AspSer: 2.736 ± 0.057	3.358AspThr: 3.358 ± 0.08	4.94AspVal: 4.94 ± 0.084	0.755AspTrp: 0.755 ± 0.031	1.084AspTyr: 1.084 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	6.444GluAla: 6.444 ± 0.115	0.391GluCys: 0.391 ± 0.026	2.797GluAsp: 2.797 ± 0.067	3.418GluGlu: 3.418 ± 0.087	1.624GluPhe: 1.624 ± 0.054	4.179GluGly: 4.179 ± 0.076	1.757GluHis: 1.757 ± 0.049	2.787GluIle: 2.787 ± 0.063	2.051GluLys: 2.051 ± 0.07	5.566GluLeu: 5.566 ± 0.086	1.155GluMet: 1.155 ± 0.043	1.792GluAsn: 1.792 ± 0.057	2.585GluPro: 2.585 ± 0.07	2.467GluGln: 2.467 ± 0.071	4.406GluArg: 4.406 ± 0.084	2.828GluSer: 2.828 ± 0.064	3.021GluThr: 3.021 ± 0.068	4.53GluVal: 4.53 ± 0.091	0.641GluTrp: 0.641 ± 0.028	1.092GluTyr: 1.092 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.589PheAla: 3.589 ± 0.068	0.269PheCys: 0.269 ± 0.018	1.961PheAsp: 1.961 ± 0.053	1.514PheGlu: 1.514 ± 0.045	1.059PhePhe: 1.059 ± 0.044	2.949PheGly: 2.949 ± 0.08	0.588PheHis: 0.588 ± 0.027	1.34PheIle: 1.34 ± 0.05	0.56PheLys: 0.56 ± 0.027	2.564PheLeu: 2.564 ± 0.068	0.569PheMet: 0.569 ± 0.03	0.714PheAsn: 0.714 ± 0.029	1.361PhePro: 1.361 ± 0.04	0.623PheGln: 0.623 ± 0.029	1.59PheArg: 1.59 ± 0.048	1.81PheSer: 1.81 ± 0.053	2.302PheThr: 2.302 ± 0.058	2.739PheVal: 2.739 ± 0.069	0.405PheTrp: 0.405 ± 0.026	0.591PheTyr: 0.591 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	9.159GlyAla: 9.159 ± 0.136	0.824GlyCys: 0.824 ± 0.038	4.346GlyAsp: 4.346 ± 0.08	4.613GlyGlu: 4.613 ± 0.094	2.842GlyPhe: 2.842 ± 0.072	7.169GlyGly: 7.169 ± 0.14	2.211GlyHis: 2.211 ± 0.054	4.375GlyIle: 4.375 ± 0.071	3.032GlyLys: 3.032 ± 0.086	7.994GlyLeu: 7.994 ± 0.115	2.099GlyMet: 2.099 ± 0.048	2.145GlyAsn: 2.145 ± 0.056	3.737GlyPro: 3.737 ± 0.068	2.861GlyGln: 2.861 ± 0.07	5.852GlyArg: 5.852 ± 0.093	4.871GlySer: 4.871 ± 0.085	5.442GlyThr: 5.442 ± 0.089	8.003GlyVal: 8.003 ± 0.14	1.437GlyTrp: 1.437 ± 0.045	2.039GlyTyr: 2.039 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	2.858HisAla: 2.858 ± 0.076	0.22HisCys: 0.22 ± 0.018	1.591HisAsp: 1.591 ± 0.049	1.397HisGlu: 1.397 ± 0.045	0.609HisPhe: 0.609 ± 0.03	2.146HisGly: 2.146 ± 0.05	0.986HisHis: 0.986 ± 0.055	1.435HisIle: 1.435 ± 0.054	0.536HisLys: 0.536 ± 0.026	2.629HisLeu: 2.629 ± 0.071	0.549HisMet: 0.549 ± 0.026	0.763HisAsn: 0.763 ± 0.037	1.941HisPro: 1.941 ± 0.062	0.728HisGln: 0.728 ± 0.033	1.829HisArg: 1.829 ± 0.053	1.242HisSer: 1.242 ± 0.037	2.111HisThr: 2.111 ± 0.075	2.014HisVal: 2.014 ± 0.054	0.345HisTrp: 0.345 ± 0.02	0.457HisTyr: 0.457 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.533IleAla: 6.533 ± 0.11	0.407IleCys: 0.407 ± 0.022	3.439IleAsp: 3.439 ± 0.069	2.831IleGlu: 2.831 ± 0.074	1.258IlePhe: 1.258 ± 0.039	4.486IleGly: 4.486 ± 0.098	1.177IleHis: 1.177 ± 0.048	2.311IleIle: 2.311 ± 0.065	1.087IleLys: 1.087 ± 0.038	3.934IleLeu: 3.934 ± 0.093	0.797IleMet: 0.797 ± 0.037	1.501IleAsn: 1.501 ± 0.039	2.808IlePro: 2.808 ± 0.064	0.982IleGln: 0.982 ± 0.034	2.824IleArg: 2.824 ± 0.06	2.803IleSer: 2.803 ± 0.065	4.167IleThr: 4.167 ± 0.092	3.826IleVal: 3.826 ± 0.077	0.489IleTrp: 0.489 ± 0.028	0.854IleTyr: 0.854 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	3.178LysAla: 3.178 ± 0.084	0.132LysCys: 0.132 ± 0.012	1.481LysAsp: 1.481 ± 0.051	1.523LysGlu: 1.523 ± 0.053	0.65LysPhe: 0.65 ± 0.034	1.922LysGly: 1.922 ± 0.066	0.685LysHis: 0.685 ± 0.03	1.377LysIle: 1.377 ± 0.047	1.302LysLys: 1.302 ± 0.047	2.261LysLeu: 2.261 ± 0.057	0.59LysMet: 0.59 ± 0.027	1.077LysAsn: 1.077 ± 0.042	1.591LysPro: 1.591 ± 0.054	0.882LysGln: 0.882 ± 0.037	1.742LysArg: 1.742 ± 0.055	1.435LysSer: 1.435 ± 0.045	1.796LysThr: 1.796 ± 0.056	2.122LysVal: 2.122 ± 0.058	0.281LysTrp: 0.281 ± 0.016	0.609LysTyr: 0.609 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	12.708LeuAla: 12.708 ± 0.151	0.762LeuCys: 0.762 ± 0.035	5.637LeuAsp: 5.637 ± 0.08	4.888LeuGlu: 4.888 ± 0.089	2.728LeuPhe: 2.728 ± 0.072	8.248LeuGly: 8.248 ± 0.114	2.349LeuHis: 2.349 ± 0.063	4.841LeuIle: 4.841 ± 0.09	2.005LeuLys: 2.005 ± 0.056	9.543LeuLeu: 9.543 ± 0.163	1.868LeuMet: 1.868 ± 0.052	2.427LeuAsn: 2.427 ± 0.051	5.415LeuPro: 5.415 ± 0.088	2.435LeuGln: 2.435 ± 0.054	6.901LeuArg: 6.901 ± 0.104	5.59LeuSer: 5.59 ± 0.09	7.214LeuThr: 7.214 ± 0.14	7.987LeuVal: 7.987 ± 0.123	1.15LeuTrp: 1.15 ± 0.041	1.457LeuTyr: 1.457 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.441MetAla: 2.441 ± 0.057	0.198MetCys: 0.198 ± 0.017	0.959MetAsp: 0.959 ± 0.041	0.807MetGlu: 0.807 ± 0.037	0.661MetPhe: 0.661 ± 0.033	1.634MetGly: 1.634 ± 0.056	0.491MetHis: 0.491 ± 0.025	0.9MetIle: 0.9 ± 0.042	0.639MetLys: 0.639 ± 0.029	2.009MetLeu: 2.009 ± 0.054	0.409MetMet: 0.409 ± 0.023	0.724MetAsn: 0.724 ± 0.034	1.298MetPro: 1.298 ± 0.047	0.615MetGln: 0.615 ± 0.028	1.748MetArg: 1.748 ± 0.049	1.718MetSer: 1.718 ± 0.045	1.665MetThr: 1.665 ± 0.046	1.536MetVal: 1.536 ± 0.043	0.306MetTrp: 0.306 ± 0.018	0.357MetTyr: 0.357 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.068AsnAla: 3.068 ± 0.072	0.21AsnCys: 0.21 ± 0.015	1.55AsnAsp: 1.55 ± 0.047	1.395AsnGlu: 1.395 ± 0.046	0.609AsnPhe: 0.609 ± 0.028	2.266AsnGly: 2.266 ± 0.063	0.788AsnHis: 0.788 ± 0.037	1.418AsnIle: 1.418 ± 0.048	0.747AsnLys: 0.747 ± 0.032	2.422AsnLeu: 2.422 ± 0.06	0.547AsnMet: 0.547 ± 0.027	1.012AsnAsn: 1.012 ± 0.045	2.15AsnPro: 2.15 ± 0.056	0.726AsnGln: 0.726 ± 0.032	1.604AsnArg: 1.604 ± 0.05	1.476AsnSer: 1.476 ± 0.056	2.267AsnThr: 2.267 ± 0.08	1.969AsnVal: 1.969 ± 0.049	0.393AsnTrp: 0.393 ± 0.03	0.588AsnTyr: 0.588 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	6.373ProAla: 6.373 ± 0.122	0.34ProCys: 0.34 ± 0.022	3.311ProAsp: 3.311 ± 0.06	3.729ProGlu: 3.729 ± 0.072	1.46ProPhe: 1.46 ± 0.049	4.908ProGly: 4.908 ± 0.082	1.867ProHis: 1.867 ± 0.071	2.429ProIle: 2.429 ± 0.058	1.335ProLys: 1.335 ± 0.057	4.766ProLeu: 4.766 ± 0.089	1.093ProMet: 1.093 ± 0.035	1.627ProAsn: 1.627 ± 0.049	2.632ProPro: 2.632 ± 0.082	1.957ProGln: 1.957 ± 0.059	3.187ProArg: 3.187 ± 0.078	3.193ProSer: 3.193 ± 0.066	4.734ProThr: 4.734 ± 0.13	4.401ProVal: 4.401 ± 0.084	0.871ProTrp: 0.871 ± 0.031	1.116ProTyr: 1.116 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.985GlnAla: 3.985 ± 0.084	0.194GlnCys: 0.194 ± 0.016	1.203GlnAsp: 1.203 ± 0.046	1.692GlnGlu: 1.692 ± 0.051	0.866GlnPhe: 0.866 ± 0.034	2.312GlnGly: 2.312 ± 0.066	0.93GlnHis: 0.93 ± 0.037	1.473GlnIle: 1.473 ± 0.046	0.862GlnLys: 0.862 ± 0.034	3.228GlnLeu: 3.228 ± 0.068	0.737GlnMet: 0.737 ± 0.03	0.799GlnAsn: 0.799 ± 0.034	1.733GlnPro: 1.733 ± 0.048	1.319GlnGln: 1.319 ± 0.046	2.713GlnArg: 2.713 ± 0.062	1.486GlnSer: 1.486 ± 0.048	1.689GlnThr: 1.689 ± 0.05	2.738GlnVal: 2.738 ± 0.061	0.567GlnTrp: 0.567 ± 0.027	0.619GlnTyr: 0.619 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	7.461ArgAla: 7.461 ± 0.102	0.555ArgCys: 0.555 ± 0.028	3.535ArgAsp: 3.535 ± 0.083	3.985ArgGlu: 3.985 ± 0.086	2.072ArgPhe: 2.072 ± 0.057	5.061ArgGly: 5.061 ± 0.108	1.935ArgHis: 1.935 ± 0.054	3.502ArgIle: 3.502 ± 0.065	1.761ArgLys: 1.761 ± 0.051	6.672ArgLeu: 6.672 ± 0.101	1.673ArgMet: 1.673 ± 0.04	1.766ArgAsn: 1.766 ± 0.048	3.489ArgPro: 3.489 ± 0.064	2.111ArgGln: 2.111 ± 0.053	5.879ArgArg: 5.879 ± 0.111	4.17ArgSer: 4.17 ± 0.078	4.153ArgThr: 4.153 ± 0.085	5.388ArgVal: 5.388 ± 0.096	1.086ArgTrp: 1.086 ± 0.038	1.489ArgTyr: 1.489 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	6.74SerAla: 6.74 ± 0.098	0.449SerCys: 0.449 ± 0.021	2.982SerAsp: 2.982 ± 0.062	2.784SerGlu: 2.784 ± 0.065	1.778SerPhe: 1.778 ± 0.053	5.681SerGly: 5.681 ± 0.099	1.385SerHis: 1.385 ± 0.043	2.7SerIle: 2.7 ± 0.071	1.476SerLys: 1.476 ± 0.056	5.214SerLeu: 5.214 ± 0.096	1.462SerMet: 1.462 ± 0.046	1.389SerAsn: 1.389 ± 0.047	3.057SerPro: 3.057 ± 0.071	1.744SerGln: 1.744 ± 0.046	3.754SerArg: 3.754 ± 0.082	3.974SerSer: 3.974 ± 0.11	3.952SerThr: 3.952 ± 0.089	4.705SerVal: 4.705 ± 0.103	0.931SerTrp: 0.931 ± 0.037	1.128SerTyr: 1.128 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	8.098ThrAla: 8.098 ± 0.148	0.606ThrCys: 0.606 ± 0.034	3.796ThrAsp: 3.796 ± 0.082	3.127ThrGlu: 3.127 ± 0.075	1.987ThrPhe: 1.987 ± 0.054	5.88ThrGly: 5.88 ± 0.086	2.175ThrHis: 2.175 ± 0.084	3.518ThrIle: 3.518 ± 0.093	1.637ThrLys: 1.637 ± 0.048	6.354ThrLeu: 6.354 ± 0.129	1.281ThrMet: 1.281 ± 0.044	2.241ThrAsn: 2.241 ± 0.074	5.688ThrPro: 5.688 ± 0.136	2.159ThrGln: 2.159 ± 0.063	3.974ThrArg: 3.974 ± 0.073	4.138ThrSer: 4.138 ± 0.086	6.199ThrThr: 6.199 ± 0.183	5.04ThrVal: 5.04 ± 0.08	1.096ThrTrp: 1.096 ± 0.041	1.606ThrTyr: 1.606 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	10.237ValAla: 10.237 ± 0.153	0.78ValCys: 0.78 ± 0.034	4.913ValAsp: 4.913 ± 0.099	4.96ValGlu: 4.96 ± 0.093	2.56ValPhe: 2.56 ± 0.063	7.1ValGly: 7.1 ± 0.126	1.746ValHis: 1.746 ± 0.052	3.979ValIle: 3.979 ± 0.075	2.099ValLys: 2.099 ± 0.065	8.26ValLeu: 8.26 ± 0.121	1.826ValMet: 1.826 ± 0.053	1.986ValAsn: 1.986 ± 0.05	4.312ValPro: 4.312 ± 0.086	2.247ValGln: 2.247 ± 0.056	5.461ValArg: 5.461 ± 0.1	4.806ValSer: 4.806 ± 0.095	5.662ValThr: 5.662 ± 0.087	8.525ValVal: 8.525 ± 0.168	1.064ValTrp: 1.064 ± 0.044	1.394ValTyr: 1.394 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.475TrpAla: 1.475 ± 0.046	0.165TrpCys: 0.165 ± 0.015	0.694TrpAsp: 0.694 ± 0.038	0.684TrpGlu: 0.684 ± 0.029	0.55TrpPhe: 0.55 ± 0.027	1.113TrpGly: 1.113 ± 0.038	0.354TrpHis: 0.354 ± 0.019	0.693TrpIle: 0.693 ± 0.031	0.44TrpLys: 0.44 ± 0.026	1.559TrpLeu: 1.559 ± 0.05	0.348TrpMet: 0.348 ± 0.02	0.471TrpAsn: 0.471 ± 0.03	0.683TrpPro: 0.683 ± 0.034	0.559TrpGln: 0.559 ± 0.03	1.055TrpArg: 1.055 ± 0.043	0.931TrpSer: 0.931 ± 0.034	0.813TrpThr: 0.813 ± 0.035	1.101TrpVal: 1.101 ± 0.041	0.364TrpTrp: 0.364 ± 0.026	0.251TrpTyr: 0.251 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.294TyrAla: 2.294 ± 0.058	0.176TyrCys: 0.176 ± 0.016	1.196TyrAsp: 1.196 ± 0.034	1.201TyrGlu: 1.201 ± 0.044	0.604TyrPhe: 0.604 ± 0.029	1.792TyrGly: 1.792 ± 0.056	0.371TyrHis: 0.371 ± 0.025	0.793TyrIle: 0.793 ± 0.031	0.448TyrLys: 0.448 ± 0.023	2.031TyrLeu: 2.031 ± 0.051	0.316TyrMet: 0.316 ± 0.019	0.499TyrAsn: 0.499 ± 0.025	1.013TyrPro: 1.013 ± 0.035	0.584TyrGln: 0.584 ± 0.028	1.495TyrArg: 1.495 ± 0.051	1.088TyrSer: 1.088 ± 0.04	1.297TyrThr: 1.297 ± 0.043	1.64TyrVal: 1.64 ± 0.051	0.304TyrTrp: 0.304 ± 0.021	0.422TyrTyr: 0.422 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2311 proteins (781931 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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