Amino acid dipepetide frequency for Chrysochromulina parva virophage Curly

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.102AlaAla: 8.102 ± 2.91
0.15AlaCys: 0.15 ± 0.203
4.201AlaAsp: 4.201 ± 1.168
5.851AlaGlu: 5.851 ± 1.151
2.251AlaPhe: 2.251 ± 0.611
6.152AlaGly: 6.152 ± 1.453
0.75AlaHis: 0.75 ± 0.301
3.451AlaIle: 3.451 ± 0.775
3.751AlaLys: 3.751 ± 0.723
5.401AlaLeu: 5.401 ± 1.215
1.8AlaMet: 1.8 ± 0.869
4.051AlaAsn: 4.051 ± 0.664
6.602AlaPro: 6.602 ± 2.137
3.001AlaGln: 3.001 ± 1.057
3.751AlaArg: 3.751 ± 0.881
5.401AlaSer: 5.401 ± 1.003
4.951AlaThr: 4.951 ± 1.191
3.751AlaVal: 3.751 ± 0.872
0.45AlaTrp: 0.45 ± 0.208
3.151AlaTyr: 3.151 ± 0.752
0.0AlaXaa: 0.0 ± 0.0
Cys
0.3CysAla: 0.3 ± 0.213
0.3CysCys: 0.3 ± 0.202
0.3CysAsp: 0.3 ± 0.255
1.05CysGlu: 1.05 ± 0.583
0.6CysPhe: 0.6 ± 0.474
0.6CysGly: 0.6 ± 0.376
0.0CysHis: 0.0 ± 0.0
0.75CysIle: 0.75 ± 0.397
1.05CysLys: 1.05 ± 0.738
1.05CysLeu: 1.05 ± 0.604
0.0CysMet: 0.0 ± 0.0
0.6CysAsn: 0.6 ± 0.493
0.3CysPro: 0.3 ± 0.242
0.0CysGln: 0.0 ± 0.0
0.45CysArg: 0.45 ± 0.243
0.3CysSer: 0.3 ± 0.246
0.6CysThr: 0.6 ± 0.34
0.6CysVal: 0.6 ± 0.31
0.3CysTrp: 0.3 ± 0.202
0.45CysTyr: 0.45 ± 0.242
0.0CysXaa: 0.0 ± 0.0
Asp
3.451AspAla: 3.451 ± 1.018
0.3AspCys: 0.3 ± 0.261
2.401AspAsp: 2.401 ± 1.007
4.651AspGlu: 4.651 ± 0.636
2.251AspPhe: 2.251 ± 0.581
1.65AspGly: 1.65 ± 0.502
0.3AspHis: 0.3 ± 0.243
6.452AspIle: 6.452 ± 1.038
4.951AspLys: 4.951 ± 0.974
4.051AspLeu: 4.051 ± 0.764
1.8AspMet: 1.8 ± 0.519
2.701AspAsn: 2.701 ± 0.57
4.651AspPro: 4.651 ± 0.776
1.2AspGln: 1.2 ± 0.392
2.251AspArg: 2.251 ± 0.698
3.301AspSer: 3.301 ± 0.893
4.501AspThr: 4.501 ± 0.891
5.101AspVal: 5.101 ± 1.056
0.45AspTrp: 0.45 ± 0.391
2.251AspTyr: 2.251 ± 0.406
0.0AspXaa: 0.0 ± 0.0
Glu
4.351GluAla: 4.351 ± 1.057
1.35GluCys: 1.35 ± 0.622
4.051GluAsp: 4.051 ± 1.06
5.251GluGlu: 5.251 ± 1.475
2.851GluPhe: 2.851 ± 0.474
2.551GluGly: 2.551 ± 0.588
0.75GluHis: 0.75 ± 0.368
7.352GluIle: 7.352 ± 1.172
4.201GluLys: 4.201 ± 0.936
7.352GluLeu: 7.352 ± 1.334
1.95GluMet: 1.95 ± 0.523
4.051GluAsn: 4.051 ± 0.999
2.551GluPro: 2.551 ± 0.981
2.701GluGln: 2.701 ± 0.882
3.301GluArg: 3.301 ± 1.035
2.551GluSer: 2.551 ± 0.581
3.751GluThr: 3.751 ± 0.61
3.751GluVal: 3.751 ± 0.881
0.45GluTrp: 0.45 ± 0.283
1.95GluTyr: 1.95 ± 0.482
0.0GluXaa: 0.0 ± 0.0
Phe
1.95PheAla: 1.95 ± 0.484
0.15PheCys: 0.15 ± 0.153
2.701PheAsp: 2.701 ± 0.517
3.451PheGlu: 3.451 ± 0.597
1.35PhePhe: 1.35 ± 0.359
1.8PheGly: 1.8 ± 0.482
0.15PheHis: 0.15 ± 0.159
2.701PheIle: 2.701 ± 0.906
3.151PheLys: 3.151 ± 0.747
3.901PheLeu: 3.901 ± 0.723
1.05PheMet: 1.05 ± 0.375
2.851PheAsn: 2.851 ± 0.596
1.5PhePro: 1.5 ± 0.424
1.05PheGln: 1.05 ± 0.587
1.5PheArg: 1.5 ± 0.569
1.35PheSer: 1.35 ± 0.361
2.401PheThr: 2.401 ± 0.665
1.65PheVal: 1.65 ± 0.365
0.0PheTrp: 0.0 ± 0.0
2.401PheTyr: 2.401 ± 0.723
0.0PheXaa: 0.0 ± 0.0
Gly
5.401GlyAla: 5.401 ± 1.251
0.6GlyCys: 0.6 ± 0.494
1.8GlyAsp: 1.8 ± 0.527
3.001GlyGlu: 3.001 ± 0.484
1.35GlyPhe: 1.35 ± 0.447
3.901GlyGly: 3.901 ± 1.157
1.35GlyHis: 1.35 ± 0.432
4.351GlyIle: 4.351 ± 0.716
3.601GlyLys: 3.601 ± 0.582
4.201GlyLeu: 4.201 ± 0.651
1.2GlyMet: 1.2 ± 0.404
1.65GlyAsn: 1.65 ± 0.745
1.5GlyPro: 1.5 ± 0.527
1.8GlyGln: 1.8 ± 0.463
2.851GlyArg: 2.851 ± 0.584
4.951GlySer: 4.951 ± 1.314
4.051GlyThr: 4.051 ± 1.037
2.251GlyVal: 2.251 ± 0.464
0.3GlyTrp: 0.3 ± 0.155
1.5GlyTyr: 1.5 ± 0.416
0.0GlyXaa: 0.0 ± 0.0
His
0.6HisAla: 0.6 ± 0.32
0.45HisCys: 0.45 ± 0.423
1.05HisAsp: 1.05 ± 0.346
0.75HisGlu: 0.75 ± 0.443
0.45HisPhe: 0.45 ± 0.262
0.6HisGly: 0.6 ± 0.216
0.3HisHis: 0.3 ± 0.243
1.05HisIle: 1.05 ± 0.421
1.65HisLys: 1.65 ± 0.601
0.9HisLeu: 0.9 ± 0.309
0.15HisMet: 0.15 ± 0.155
1.2HisAsn: 1.2 ± 0.31
1.05HisPro: 1.05 ± 0.395
0.3HisGln: 0.3 ± 0.238
1.2HisArg: 1.2 ± 0.636
1.35HisSer: 1.35 ± 0.702
0.9HisThr: 0.9 ± 0.367
0.6HisVal: 0.6 ± 0.317
0.15HisTrp: 0.15 ± 0.155
0.6HisTyr: 0.6 ± 0.237
0.0HisXaa: 0.0 ± 0.0
Ile
4.501IleAla: 4.501 ± 1.371
0.6IleCys: 0.6 ± 0.38
5.101IleAsp: 5.101 ± 0.686
5.851IleGlu: 5.851 ± 0.845
2.701IlePhe: 2.701 ± 0.617
3.901IleGly: 3.901 ± 0.643
1.05IleHis: 1.05 ± 0.529
5.251IleIle: 5.251 ± 1.714
4.801IleLys: 4.801 ± 1.285
4.951IleLeu: 4.951 ± 1.183
1.8IleMet: 1.8 ± 0.53
5.701IleAsn: 5.701 ± 1.135
3.901IlePro: 3.901 ± 0.63
3.151IleGln: 3.151 ± 0.583
3.601IleArg: 3.601 ± 0.917
5.551IleSer: 5.551 ± 1.075
4.801IleThr: 4.801 ± 0.563
3.751IleVal: 3.751 ± 0.924
0.3IleTrp: 0.3 ± 0.21
2.551IleTyr: 2.551 ± 0.949
0.0IleXaa: 0.0 ± 0.0
Lys
6.002LysAla: 6.002 ± 0.871
0.15LysCys: 0.15 ± 0.152
3.901LysAsp: 3.901 ± 0.841
3.451LysGlu: 3.451 ± 0.87
3.001LysPhe: 3.001 ± 0.486
4.201LysGly: 4.201 ± 0.713
1.35LysHis: 1.35 ± 0.733
6.152LysIle: 6.152 ± 0.942
6.602LysLys: 6.602 ± 1.851
5.101LysLeu: 5.101 ± 1.272
1.95LysMet: 1.95 ± 0.602
6.452LysAsn: 6.452 ± 1.58
4.951LysPro: 4.951 ± 1.143
2.251LysGln: 2.251 ± 0.593
3.451LysArg: 3.451 ± 1.104
3.751LysSer: 3.751 ± 0.709
4.351LysThr: 4.351 ± 1.118
2.551LysVal: 2.551 ± 0.656
0.45LysTrp: 0.45 ± 0.314
3.001LysTyr: 3.001 ± 0.747
0.0LysXaa: 0.0 ± 0.0
Leu
4.651LeuAla: 4.651 ± 0.826
0.9LeuCys: 0.9 ± 0.562
6.002LeuAsp: 6.002 ± 0.923
5.551LeuGlu: 5.551 ± 0.614
2.551LeuPhe: 2.551 ± 0.669
3.901LeuGly: 3.901 ± 0.526
1.05LeuHis: 1.05 ± 0.393
4.201LeuIle: 4.201 ± 0.714
6.302LeuLys: 6.302 ± 0.827
4.051LeuLeu: 4.051 ± 0.853
2.101LeuMet: 2.101 ± 0.595
6.752LeuAsn: 6.752 ± 1.435
4.501LeuPro: 4.501 ± 0.763
3.451LeuGln: 3.451 ± 0.842
2.551LeuArg: 2.551 ± 0.636
4.651LeuSer: 4.651 ± 1.024
6.752LeuThr: 6.752 ± 1.263
4.051LeuVal: 4.051 ± 0.765
0.15LeuTrp: 0.15 ± 0.213
2.551LeuTyr: 2.551 ± 0.471
0.0LeuXaa: 0.0 ± 0.0
Met
1.95MetAla: 1.95 ± 0.579
0.0MetCys: 0.0 ± 0.0
1.05MetAsp: 1.05 ± 0.504
2.551MetGlu: 2.551 ± 0.56
0.9MetPhe: 0.9 ± 0.454
0.6MetGly: 0.6 ± 0.327
0.0MetHis: 0.0 ± 0.0
0.75MetIle: 0.75 ± 0.276
2.701MetLys: 2.701 ± 1.039
2.251MetLeu: 2.251 ± 0.493
0.45MetMet: 0.45 ± 0.199
2.401MetAsn: 2.401 ± 0.524
1.95MetPro: 1.95 ± 0.536
0.0MetGln: 0.0 ± 0.0
0.75MetArg: 0.75 ± 0.278
1.5MetSer: 1.5 ± 0.394
2.401MetThr: 2.401 ± 0.568
1.5MetVal: 1.5 ± 0.682
0.0MetTrp: 0.0 ± 0.0
1.05MetTyr: 1.05 ± 0.396
0.0MetXaa: 0.0 ± 0.0
Asn
3.751AsnAla: 3.751 ± 0.814
0.75AsnCys: 0.75 ± 0.53
2.701AsnAsp: 2.701 ± 0.915
4.651AsnGlu: 4.651 ± 1.033
3.151AsnPhe: 3.151 ± 0.903
2.551AsnGly: 2.551 ± 0.78
1.05AsnHis: 1.05 ± 0.539
4.801AsnIle: 4.801 ± 1.085
4.051AsnLys: 4.051 ± 1.236
6.002AsnLeu: 6.002 ± 0.742
1.95AsnMet: 1.95 ± 0.859
3.751AsnAsn: 3.751 ± 1.64
2.851AsnPro: 2.851 ± 0.711
3.301AsnGln: 3.301 ± 0.671
2.551AsnArg: 2.551 ± 0.633
3.751AsnSer: 3.751 ± 0.818
4.801AsnThr: 4.801 ± 1.127
4.501AsnVal: 4.501 ± 0.798
0.9AsnTrp: 0.9 ± 0.443
3.301AsnTyr: 3.301 ± 1.102
0.0AsnXaa: 0.0 ± 0.0
Pro
5.551ProAla: 5.551 ± 1.193
0.3ProCys: 0.3 ± 0.255
4.351ProAsp: 4.351 ± 1.176
5.851ProGlu: 5.851 ± 0.931
1.2ProPhe: 1.2 ± 0.402
2.401ProGly: 2.401 ± 1.056
0.0ProHis: 0.0 ± 0.0
2.101ProIle: 2.101 ± 0.512
4.051ProLys: 4.051 ± 0.988
1.8ProLeu: 1.8 ± 0.734
1.65ProMet: 1.65 ± 0.554
2.851ProAsn: 2.851 ± 0.939
4.801ProPro: 4.801 ± 1.613
2.251ProGln: 2.251 ± 0.701
1.35ProArg: 1.35 ± 0.472
3.751ProSer: 3.751 ± 0.865
5.101ProThr: 5.101 ± 1.926
6.152ProVal: 6.152 ± 1.341
0.0ProTrp: 0.0 ± 0.0
1.95ProTyr: 1.95 ± 0.761
0.0ProXaa: 0.0 ± 0.0
Gln
1.65GlnAla: 1.65 ± 0.577
0.45GlnCys: 0.45 ± 0.339
1.95GlnAsp: 1.95 ± 0.587
1.95GlnGlu: 1.95 ± 0.739
0.9GlnPhe: 0.9 ± 0.317
1.2GlnGly: 1.2 ± 0.41
1.35GlnHis: 1.35 ± 0.508
2.701GlnIle: 2.701 ± 0.928
2.401GlnLys: 2.401 ± 0.538
2.251GlnLeu: 2.251 ± 0.47
0.75GlnMet: 0.75 ± 0.304
2.701GlnAsn: 2.701 ± 0.637
1.5GlnPro: 1.5 ± 0.379
1.95GlnGln: 1.95 ± 0.685
1.95GlnArg: 1.95 ± 0.704
3.751GlnSer: 3.751 ± 0.827
1.8GlnThr: 1.8 ± 0.579
2.701GlnVal: 2.701 ± 0.48
0.0GlnTrp: 0.0 ± 0.0
1.35GlnTyr: 1.35 ± 0.429
0.0GlnXaa: 0.0 ± 0.0
Arg
3.751ArgAla: 3.751 ± 0.79
0.6ArgCys: 0.6 ± 0.343
1.65ArgAsp: 1.65 ± 0.45
2.551ArgGlu: 2.551 ± 0.496
1.95ArgPhe: 1.95 ± 0.836
2.401ArgGly: 2.401 ± 0.466
1.5ArgHis: 1.5 ± 0.459
3.451ArgIle: 3.451 ± 0.372
2.851ArgLys: 2.851 ± 0.758
5.101ArgLeu: 5.101 ± 0.765
1.35ArgMet: 1.35 ± 0.495
2.701ArgAsn: 2.701 ± 0.554
1.65ArgPro: 1.65 ± 0.533
1.5ArgGln: 1.5 ± 0.507
1.5ArgArg: 1.5 ± 0.459
1.5ArgSer: 1.5 ± 0.559
2.551ArgThr: 2.551 ± 0.587
1.95ArgVal: 1.95 ± 0.416
0.3ArgTrp: 0.3 ± 0.243
1.95ArgTyr: 1.95 ± 0.57
0.0ArgXaa: 0.0 ± 0.0
Ser
6.302SerAla: 6.302 ± 1.432
0.45SerCys: 0.45 ± 0.475
4.201SerAsp: 4.201 ± 0.779
2.551SerGlu: 2.551 ± 0.509
2.401SerPhe: 2.401 ± 0.585
4.651SerGly: 4.651 ± 1.183
1.35SerHis: 1.35 ± 0.435
6.452SerIle: 6.452 ± 0.877
5.101SerLys: 5.101 ± 1.018
5.251SerLeu: 5.251 ± 0.911
1.95SerMet: 1.95 ± 0.748
3.751SerAsn: 3.751 ± 1.263
1.5SerPro: 1.5 ± 0.4
1.35SerGln: 1.35 ± 0.502
3.151SerArg: 3.151 ± 0.488
6.752SerSer: 6.752 ± 1.412
3.451SerThr: 3.451 ± 0.967
3.451SerVal: 3.451 ± 0.626
0.15SerTrp: 0.15 ± 0.201
2.251SerTyr: 2.251 ± 0.843
0.0SerXaa: 0.0 ± 0.0
Thr
6.452ThrAla: 6.452 ± 1.692
0.9ThrCys: 0.9 ± 0.45
4.351ThrAsp: 4.351 ± 0.697
3.001ThrGlu: 3.001 ± 0.468
3.451ThrPhe: 3.451 ± 0.756
3.901ThrGly: 3.901 ± 1.034
0.9ThrHis: 0.9 ± 0.391
4.651ThrIle: 4.651 ± 1.114
3.451ThrLys: 3.451 ± 0.656
5.701ThrLeu: 5.701 ± 1.252
1.35ThrMet: 1.35 ± 0.431
3.901ThrAsn: 3.901 ± 0.794
5.701ThrPro: 5.701 ± 1.904
2.551ThrGln: 2.551 ± 0.513
2.551ThrArg: 2.551 ± 0.734
4.651ThrSer: 4.651 ± 0.871
3.451ThrThr: 3.451 ± 0.841
4.051ThrVal: 4.051 ± 0.763
0.45ThrTrp: 0.45 ± 0.317
2.101ThrTyr: 2.101 ± 0.743
0.0ThrXaa: 0.0 ± 0.0
Val
5.701ValAla: 5.701 ± 1.056
0.3ValCys: 0.3 ± 0.246
3.901ValAsp: 3.901 ± 0.715
3.301ValGlu: 3.301 ± 0.551
1.95ValPhe: 1.95 ± 0.55
2.701ValGly: 2.701 ± 0.547
0.6ValHis: 0.6 ± 0.323
4.201ValIle: 4.201 ± 0.636
4.051ValLys: 4.051 ± 0.669
4.651ValLeu: 4.651 ± 0.753
0.75ValMet: 0.75 ± 0.335
4.351ValAsn: 4.351 ± 1.145
4.201ValPro: 4.201 ± 1.324
1.95ValGln: 1.95 ± 0.489
2.401ValArg: 2.401 ± 0.697
3.751ValSer: 3.751 ± 0.951
3.601ValThr: 3.601 ± 0.663
3.151ValVal: 3.151 ± 0.73
0.3ValTrp: 0.3 ± 0.29
1.8ValTyr: 1.8 ± 0.596
0.0ValXaa: 0.0 ± 0.0
Trp
0.45TrpAla: 0.45 ± 0.209
0.15TrpCys: 0.15 ± 0.153
0.45TrpAsp: 0.45 ± 0.255
0.15TrpGlu: 0.15 ± 0.109
0.0TrpPhe: 0.0 ± 0.0
0.3TrpGly: 0.3 ± 0.212
0.0TrpHis: 0.0 ± 0.0
0.3TrpIle: 0.3 ± 0.31
0.9TrpLys: 0.9 ± 0.418
0.3TrpLeu: 0.3 ± 0.148
0.0TrpMet: 0.0 ± 0.0
0.75TrpAsn: 0.75 ± 0.561
0.15TrpPro: 0.15 ± 0.201
0.0TrpGln: 0.0 ± 0.0
0.3TrpArg: 0.3 ± 0.202
0.3TrpSer: 0.3 ± 0.148
0.3TrpThr: 0.3 ± 0.244
0.15TrpVal: 0.15 ± 0.173
0.0TrpTrp: 0.0 ± 0.0
0.3TrpTyr: 0.3 ± 0.237
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.101TyrAla: 2.101 ± 0.38
0.75TyrCys: 0.75 ± 0.439
2.551TyrAsp: 2.551 ± 0.49
1.65TyrGlu: 1.65 ± 0.501
1.8TyrPhe: 1.8 ± 0.774
1.65TyrGly: 1.65 ± 0.585
1.5TyrHis: 1.5 ± 0.543
2.701TyrIle: 2.701 ± 0.763
3.451TyrLys: 3.451 ± 0.657
2.401TyrLeu: 2.401 ± 0.935
0.6TyrMet: 0.6 ± 0.453
1.95TyrAsn: 1.95 ± 0.561
1.65TyrPro: 1.65 ± 0.631
1.5TyrGln: 1.5 ± 0.355
1.35TyrArg: 1.35 ± 0.651
3.601TyrSer: 3.601 ± 0.6
3.001TyrThr: 3.001 ± 0.71
1.95TyrVal: 1.95 ± 0.618
0.15TyrTrp: 0.15 ± 0.215
1.65TyrTyr: 1.65 ± 0.513
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 19 proteins (6666 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski