Amino acid dipepetide frequency for Phaethon lepturus (White-tailed tropicbird)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.532AlaAla: 5.532 ± 0.058	1.305AlaCys: 1.305 ± 0.02	2.966AlaAsp: 2.966 ± 0.03	4.535AlaGlu: 4.535 ± 0.041	2.625AlaPhe: 2.625 ± 0.03	3.816AlaGly: 3.816 ± 0.038	1.354AlaHis: 1.354 ± 0.02	3.114AlaIle: 3.114 ± 0.032	3.749AlaLys: 3.749 ± 0.036	6.36AlaLeu: 6.36 ± 0.05	1.518AlaMet: 1.518 ± 0.022	2.253AlaAsn: 2.253 ± 0.024	2.875AlaPro: 2.875 ± 0.037	2.738AlaGln: 2.738 ± 0.032	2.847AlaArg: 2.847 ± 0.029	5.152AlaSer: 5.152 ± 0.043	3.327AlaThr: 3.327 ± 0.027	4.828AlaVal: 4.828 ± 0.041	0.697AlaTrp: 0.697 ± 0.013	1.634AlaTyr: 1.634 ± 0.02	0.001AlaXaa: 0.001 ± 0.0
Cys	1.155CysAla: 1.155 ± 0.022	0.652CysCys: 0.652 ± 0.016	1.053CysAsp: 1.053 ± 0.027	1.314CysGlu: 1.314 ± 0.031	0.934CysPhe: 0.934 ± 0.017	1.423CysGly: 1.423 ± 0.028	0.639CysHis: 0.639 ± 0.016	1.189CysIle: 1.189 ± 0.025	1.353CysLys: 1.353 ± 0.024	2.125CysLeu: 2.125 ± 0.028	0.456CysMet: 0.456 ± 0.012	0.932CysAsn: 0.932 ± 0.016	1.221CysPro: 1.221 ± 0.032	1.07CysGln: 1.07 ± 0.024	1.219CysArg: 1.219 ± 0.022	2.046CysSer: 2.046 ± 0.032	1.192CysThr: 1.192 ± 0.024	1.344CysVal: 1.344 ± 0.024	0.299CysTrp: 0.299 ± 0.009	0.687CysTyr: 0.687 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	2.917AspAla: 2.917 ± 0.027	1.106AspCys: 1.106 ± 0.021	2.915AspAsp: 2.915 ± 0.044	3.731AspGlu: 3.731 ± 0.041	2.316AspPhe: 2.316 ± 0.024	3.31AspGly: 3.31 ± 0.039	1.161AspHis: 1.161 ± 0.019	3.031AspIle: 3.031 ± 0.03	2.852AspLys: 2.852 ± 0.029	5.119AspLeu: 5.119 ± 0.043	1.199AspMet: 1.199 ± 0.017	2.015AspAsn: 2.015 ± 0.027	2.644AspPro: 2.644 ± 0.027	1.875AspGln: 1.875 ± 0.022	2.388AspArg: 2.388 ± 0.03	4.173AspSer: 4.173 ± 0.04	2.534AspThr: 2.534 ± 0.024	3.25AspVal: 3.25 ± 0.031	0.667AspTrp: 0.667 ± 0.013	1.655AspTyr: 1.655 ± 0.021	0.001AspXaa: 0.001 ± 0.0
Glu	4.658GluAla: 4.658 ± 0.04	1.345GluCys: 1.345 ± 0.037	4.569GluAsp: 4.569 ± 0.043	7.992GluGlu: 7.992 ± 0.085	2.224GluPhe: 2.224 ± 0.025	3.958GluGly: 3.958 ± 0.048	1.572GluHis: 1.572 ± 0.019	3.604GluIle: 3.604 ± 0.038	5.865GluLys: 5.865 ± 0.068	6.392GluLeu: 6.392 ± 0.058	1.813GluMet: 1.813 ± 0.023	3.534GluAsn: 3.534 ± 0.032	2.498GluPro: 2.498 ± 0.027	3.275GluGln: 3.275 ± 0.041	3.904GluArg: 3.904 ± 0.048	4.545GluSer: 4.545 ± 0.048	3.632GluThr: 3.632 ± 0.037	4.448GluVal: 4.448 ± 0.039	0.753GluTrp: 0.753 ± 0.016	1.86GluTyr: 1.86 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	2.147PheAla: 2.147 ± 0.022	1.018PheCys: 1.018 ± 0.016	1.847PheAsp: 1.847 ± 0.022	2.169PheGlu: 2.169 ± 0.024	1.867PhePhe: 1.867 ± 0.03	2.315PheGly: 2.315 ± 0.03	1.094PheHis: 1.094 ± 0.018	2.13PheIle: 2.13 ± 0.029	2.135PheLys: 2.135 ± 0.025	4.22PheLeu: 4.22 ± 0.046	0.803PheMet: 0.803 ± 0.015	1.549PheAsn: 1.549 ± 0.025	1.958PhePro: 1.958 ± 0.028	1.853PheGln: 1.853 ± 0.023	1.971PheArg: 1.971 ± 0.027	3.498PheSer: 3.498 ± 0.037	2.307PheThr: 2.307 ± 0.026	2.392PheVal: 2.392 ± 0.031	0.521PheTrp: 0.521 ± 0.014	1.348PheTyr: 1.348 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	3.366GlyAla: 3.366 ± 0.035	1.226GlyCys: 1.226 ± 0.024	2.945GlyAsp: 2.945 ± 0.034	3.743GlyGlu: 3.743 ± 0.043	2.483GlyPhe: 2.483 ± 0.035	3.777GlyGly: 3.777 ± 0.055	1.472GlyHis: 1.472 ± 0.024	3.144GlyIle: 3.144 ± 0.032	4.007GlyLys: 4.007 ± 0.043	5.093GlyLeu: 5.093 ± 0.049	1.398GlyMet: 1.398 ± 0.023	2.646GlyAsn: 2.646 ± 0.034	2.757GlyPro: 2.757 ± 0.083	2.492GlyGln: 2.492 ± 0.037	3.169GlyArg: 3.169 ± 0.05	4.973GlySer: 4.973 ± 0.05	3.385GlyThr: 3.385 ± 0.036	3.41GlyVal: 3.41 ± 0.037	0.75GlyTrp: 0.75 ± 0.018	1.881GlyTyr: 1.881 ± 0.027	0.001GlyXaa: 0.001 ± 0.001
His	1.344HisAla: 1.344 ± 0.018	0.719HisCys: 0.719 ± 0.015	0.946HisAsp: 0.946 ± 0.017	1.373HisGlu: 1.373 ± 0.02	1.092HisPhe: 1.092 ± 0.018	1.445HisGly: 1.445 ± 0.023	0.849HisHis: 0.849 ± 0.019	1.365HisIle: 1.365 ± 0.018	1.408HisLys: 1.408 ± 0.019	2.79HisLeu: 2.79 ± 0.024	0.606HisMet: 0.606 ± 0.013	1.0HisAsn: 1.0 ± 0.017	1.455HisPro: 1.455 ± 0.023	1.177HisGln: 1.177 ± 0.021	1.458HisArg: 1.458 ± 0.023	2.167HisSer: 2.167 ± 0.026	1.284HisThr: 1.284 ± 0.019	1.536HisVal: 1.536 ± 0.02	0.399HisTrp: 0.399 ± 0.011	0.859HisTyr: 0.859 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	3.056IleAla: 3.056 ± 0.031	1.242IleCys: 1.242 ± 0.022	2.389IleAsp: 2.389 ± 0.027	2.981IleGlu: 2.981 ± 0.034	2.213IlePhe: 2.213 ± 0.027	2.525IleGly: 2.525 ± 0.029	1.408IleHis: 1.408 ± 0.018	2.756IleIle: 2.756 ± 0.032	3.1IleLys: 3.1 ± 0.033	5.035IleLeu: 5.035 ± 0.048	1.109IleMet: 1.109 ± 0.017	2.224IleAsn: 2.224 ± 0.027	2.852IlePro: 2.852 ± 0.03	2.524IleGln: 2.524 ± 0.027	2.594IleArg: 2.594 ± 0.024	4.15IleSer: 4.15 ± 0.036	2.93IleThr: 2.93 ± 0.028	2.993IleVal: 2.993 ± 0.033	0.593IleTrp: 0.593 ± 0.014	1.619IleTyr: 1.619 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	4.083LysAla: 4.083 ± 0.034	1.253LysCys: 1.253 ± 0.022	3.593LysAsp: 3.593 ± 0.036	5.923LysGlu: 5.923 ± 0.075	1.992LysPhe: 1.992 ± 0.023	3.437LysGly: 3.437 ± 0.041	1.627LysHis: 1.627 ± 0.021	3.288LysIle: 3.288 ± 0.031	5.55LysLys: 5.55 ± 0.068	5.824LysLeu: 5.824 ± 0.057	1.585LysMet: 1.585 ± 0.021	2.898LysAsn: 2.898 ± 0.027	3.097LysPro: 3.097 ± 0.036	3.06LysGln: 3.06 ± 0.033	3.557LysArg: 3.557 ± 0.037	4.306LysSer: 4.306 ± 0.044	3.466LysThr: 3.466 ± 0.036	3.852LysVal: 3.852 ± 0.037	0.685LysTrp: 0.685 ± 0.014	1.898LysTyr: 1.898 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	6.154LeuAla: 6.154 ± 0.053	2.184LeuCys: 2.184 ± 0.029	4.928LeuAsp: 4.928 ± 0.046	7.1LeuGlu: 7.1 ± 0.067	3.601LeuPhe: 3.601 ± 0.042	5.127LeuGly: 5.127 ± 0.044	2.705LeuHis: 2.705 ± 0.032	4.322LeuIle: 4.322 ± 0.037	6.503LeuLys: 6.503 ± 0.051	9.974LeuLeu: 9.974 ± 0.086	2.062LeuMet: 2.062 ± 0.026	3.983LeuAsn: 3.983 ± 0.035	5.38LeuPro: 5.38 ± 0.046	5.692LeuGln: 5.692 ± 0.057	5.146LeuArg: 5.146 ± 0.047	7.77LeuSer: 7.77 ± 0.049	5.009LeuThr: 5.009 ± 0.045	5.447LeuVal: 5.447 ± 0.044	1.082LeuTrp: 1.082 ± 0.022	2.806LeuTyr: 2.806 ± 0.035	0.001LeuXaa: 0.001 ± 0.0
Met	1.628MetAla: 1.628 ± 0.021	0.444MetCys: 0.444 ± 0.012	1.327MetAsp: 1.327 ± 0.019	1.941MetGlu: 1.941 ± 0.027	0.856MetPhe: 0.856 ± 0.016	1.247MetGly: 1.247 ± 0.021	0.529MetHis: 0.529 ± 0.011	1.006MetIle: 1.006 ± 0.017	1.625MetLys: 1.625 ± 0.024	2.133MetLeu: 2.133 ± 0.027	0.637MetMet: 0.637 ± 0.014	1.007MetAsn: 1.007 ± 0.018	1.048MetPro: 1.048 ± 0.018	1.043MetGln: 1.043 ± 0.019	1.06MetArg: 1.06 ± 0.018	1.578MetSer: 1.578 ± 0.022	1.172MetThr: 1.172 ± 0.017	1.478MetVal: 1.478 ± 0.019	0.259MetTrp: 0.259 ± 0.008	0.675MetTyr: 0.675 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.377AsnAla: 2.377 ± 0.026	1.003AsnCys: 1.003 ± 0.021	1.758AsnAsp: 1.758 ± 0.024	2.643AsnGlu: 2.643 ± 0.031	1.685AsnPhe: 1.685 ± 0.024	2.806AsnGly: 2.806 ± 0.037	1.027AsnHis: 1.027 ± 0.015	2.602AsnIle: 2.602 ± 0.028	2.671AsnLys: 2.671 ± 0.031	4.149AsnLeu: 4.149 ± 0.035	1.046AsnMet: 1.046 ± 0.015	1.873AsnAsn: 1.873 ± 0.026	2.32AsnPro: 2.32 ± 0.03	1.754AsnGln: 1.754 ± 0.024	2.077AsnArg: 2.077 ± 0.026	3.5AsnSer: 3.5 ± 0.037	2.316AsnThr: 2.316 ± 0.024	2.524AsnVal: 2.524 ± 0.027	0.513AsnTrp: 0.513 ± 0.012	1.345AsnTyr: 1.345 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	3.633ProAla: 3.633 ± 0.044	1.034ProCys: 1.034 ± 0.026	2.615ProAsp: 2.615 ± 0.029	3.836ProGlu: 3.836 ± 0.038	1.902ProPhe: 1.902 ± 0.029	3.579ProGly: 3.579 ± 0.094	1.216ProHis: 1.216 ± 0.023	1.992ProIle: 1.992 ± 0.028	2.734ProLys: 2.734 ± 0.032	4.592ProLeu: 4.592 ± 0.041	0.969ProMet: 0.969 ± 0.017	1.941ProAsn: 1.941 ± 0.029	4.171ProPro: 4.171 ± 0.074	2.333ProGln: 2.333 ± 0.034	2.524ProArg: 2.524 ± 0.031	4.858ProSer: 4.858 ± 0.051	2.661ProThr: 2.661 ± 0.031	3.695ProVal: 3.695 ± 0.035	0.553ProTrp: 0.553 ± 0.014	1.476ProTyr: 1.476 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.053GlnAla: 3.053 ± 0.036	0.978GlnCys: 0.978 ± 0.021	2.283GlnAsp: 2.283 ± 0.026	3.747GlnGlu: 3.747 ± 0.043	1.485GlnPhe: 1.485 ± 0.02	2.507GlnGly: 2.507 ± 0.037	1.306GlnHis: 1.306 ± 0.019	2.297GlnIle: 2.297 ± 0.026	3.244GlnLys: 3.244 ± 0.043	4.647GlnLeu: 4.647 ± 0.049	1.132GlnMet: 1.132 ± 0.019	2.111GlnAsn: 2.111 ± 0.025	2.322GlnPro: 2.322 ± 0.04	3.088GlnGln: 3.088 ± 0.064	2.637GlnArg: 2.637 ± 0.026	3.228GlnSer: 3.228 ± 0.039	2.395GlnThr: 2.395 ± 0.031	2.754GlnVal: 2.754 ± 0.031	0.52GlnTrp: 0.52 ± 0.012	1.33GlnTyr: 1.33 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	2.974ArgAla: 2.974 ± 0.03	1.112ArgCys: 1.112 ± 0.028	2.579ArgAsp: 2.579 ± 0.032	3.765ArgGlu: 3.765 ± 0.046	1.955ArgPhe: 1.955 ± 0.023	2.819ArgGly: 2.819 ± 0.044	1.422ArgHis: 1.422 ± 0.02	2.609ArgIle: 2.609 ± 0.03	4.05ArgLys: 4.05 ± 0.049	4.936ArgLeu: 4.936 ± 0.045	1.175ArgMet: 1.175 ± 0.017	2.267ArgAsn: 2.267 ± 0.028	2.367ArgPro: 2.367 ± 0.03	2.471ArgGln: 2.471 ± 0.027	3.62ArgArg: 3.62 ± 0.044	3.893ArgSer: 3.893 ± 0.046	2.675ArgThr: 2.675 ± 0.031	2.941ArgVal: 2.941 ± 0.03	0.624ArgTrp: 0.624 ± 0.014	1.594ArgTyr: 1.594 ± 0.022	0.001ArgXaa: 0.001 ± 0.0
Ser	5.045SerAla: 5.045 ± 0.049	1.817SerCys: 1.817 ± 0.029	4.086SerAsp: 4.086 ± 0.038	5.135SerGlu: 5.135 ± 0.047	3.167SerPhe: 3.167 ± 0.033	4.905SerGly: 4.905 ± 0.05	2.009SerHis: 2.009 ± 0.028	3.567SerIle: 3.567 ± 0.032	4.576SerLys: 4.576 ± 0.047	7.987SerLeu: 7.987 ± 0.059	1.631SerMet: 1.631 ± 0.021	3.147SerAsn: 3.147 ± 0.032	5.1SerPro: 5.1 ± 0.062	3.686SerGln: 3.686 ± 0.045	4.014SerArg: 4.014 ± 0.043	9.102SerSer: 9.102 ± 0.108	4.544SerThr: 4.544 ± 0.039	5.082SerVal: 5.082 ± 0.04	0.981SerTrp: 0.981 ± 0.017	2.233SerTyr: 2.233 ± 0.029	0.001SerXaa: 0.001 ± 0.0
Thr	3.805ThrAla: 3.805 ± 0.034	1.306ThrCys: 1.306 ± 0.031	2.752ThrAsp: 2.752 ± 0.027	3.827ThrGlu: 3.827 ± 0.039	2.219ThrPhe: 2.219 ± 0.024	3.412ThrGly: 3.412 ± 0.036	1.174ThrHis: 1.174 ± 0.019	2.607ThrIle: 2.607 ± 0.033	2.994ThrLys: 2.994 ± 0.029	5.15ThrLeu: 5.15 ± 0.04	1.145ThrMet: 1.145 ± 0.019	1.999ThrAsn: 1.999 ± 0.024	3.066ThrPro: 3.066 ± 0.038	2.172ThrGln: 2.172 ± 0.028	2.302ThrArg: 2.302 ± 0.026	4.645ThrSer: 4.645 ± 0.047	3.039ThrThr: 3.039 ± 0.039	4.163ThrVal: 4.163 ± 0.043	0.661ThrTrp: 0.661 ± 0.013	1.586ThrTyr: 1.586 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	4.055ValAla: 4.055 ± 0.038	1.537ValCys: 1.537 ± 0.025	3.141ValAsp: 3.141 ± 0.03	4.067ValGlu: 4.067 ± 0.038	2.67ValPhe: 2.67 ± 0.034	3.279ValGly: 3.279 ± 0.036	1.595ValHis: 1.595 ± 0.021	3.347ValIle: 3.347 ± 0.032	3.931ValLys: 3.931 ± 0.037	6.282ValLeu: 6.282 ± 0.06	1.4ValMet: 1.4 ± 0.02	2.635ValAsn: 2.635 ± 0.033	3.389ValPro: 3.389 ± 0.031	2.866ValGln: 2.866 ± 0.028	2.991ValArg: 2.991 ± 0.026	4.962ValSer: 4.962 ± 0.04	3.858ValThr: 3.858 ± 0.039	4.291ValVal: 4.291 ± 0.045	0.724ValTrp: 0.724 ± 0.016	1.857ValTyr: 1.857 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	0.667TrpAla: 0.667 ± 0.014	0.239TrpCys: 0.239 ± 0.008	0.684TrpAsp: 0.684 ± 0.015	0.775TrpGlu: 0.775 ± 0.017	0.453TrpPhe: 0.453 ± 0.01	0.644TrpGly: 0.644 ± 0.018	0.313TrpHis: 0.313 ± 0.008	0.63TrpIle: 0.63 ± 0.013	0.903TrpLys: 0.903 ± 0.014	1.177TrpLeu: 1.177 ± 0.021	0.32TrpMet: 0.32 ± 0.009	0.655TrpAsn: 0.655 ± 0.015	0.428TrpPro: 0.428 ± 0.012	0.556TrpGln: 0.556 ± 0.012	0.66TrpArg: 0.66 ± 0.013	0.885TrpSer: 0.885 ± 0.02	0.64TrpThr: 0.64 ± 0.016	0.663TrpVal: 0.663 ± 0.013	0.186TrpTrp: 0.186 ± 0.008	0.391TrpTyr: 0.391 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.577TyrAla: 1.577 ± 0.021	0.784TyrCys: 0.784 ± 0.017	1.478TyrAsp: 1.478 ± 0.021	1.848TyrGlu: 1.848 ± 0.023	1.406TyrPhe: 1.406 ± 0.027	1.786TyrGly: 1.786 ± 0.023	0.801TyrHis: 0.801 ± 0.013	1.695TyrIle: 1.695 ± 0.022	1.723TyrLys: 1.723 ± 0.023	2.99TyrLeu: 2.99 ± 0.034	0.687TyrMet: 0.687 ± 0.013	1.319TyrAsn: 1.319 ± 0.019	1.366TyrPro: 1.366 ± 0.019	1.34TyrGln: 1.34 ± 0.018	1.71TyrArg: 1.71 ± 0.025	2.383TyrSer: 2.383 ± 0.027	1.659TyrThr: 1.659 ± 0.021	1.786TyrVal: 1.786 ± 0.023	0.4TyrTrp: 0.4 ± 0.012	1.117TyrTyr: 1.117 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.027XaaXaa: 0.027 ± 0.007

Statistics based on 9152 proteins (3916303 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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