Amino acid dipepetide frequency for Paraburkholderia sartisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.987AlaAla: 16.987 ± 0.155	1.311AlaCys: 1.311 ± 0.027	6.376AlaAsp: 6.376 ± 0.073	5.574AlaGlu: 5.574 ± 0.07	4.508AlaPhe: 4.508 ± 0.053	10.806AlaGly: 10.806 ± 0.115	2.944AlaHis: 2.944 ± 0.044	5.899AlaIle: 5.899 ± 0.065	3.698AlaLys: 3.698 ± 0.066	14.102AlaLeu: 14.102 ± 0.107	3.27AlaMet: 3.27 ± 0.045	3.252AlaAsn: 3.252 ± 0.055	5.79AlaPro: 5.79 ± 0.082	5.048AlaGln: 5.048 ± 0.069	9.064AlaArg: 9.064 ± 0.093	7.553AlaSer: 7.553 ± 0.075	6.75AlaThr: 6.75 ± 0.092	8.823AlaVal: 8.823 ± 0.078	1.759AlaTrp: 1.759 ± 0.036	2.592AlaTyr: 2.592 ± 0.036	0.0AlaXaa: 0.0 ± 0.0
Cys	1.221CysAla: 1.221 ± 0.026	0.121CysCys: 0.121 ± 0.009	0.542CysAsp: 0.542 ± 0.018	0.477CysGlu: 0.477 ± 0.016	0.333CysPhe: 0.333 ± 0.014	1.015CysGly: 1.015 ± 0.028	0.255CysHis: 0.255 ± 0.012	0.4CysIle: 0.4 ± 0.017	0.213CysLys: 0.213 ± 0.013	0.787CysLeu: 0.787 ± 0.025	0.205CysMet: 0.205 ± 0.01	0.243CysAsn: 0.243 ± 0.011	0.454CysPro: 0.454 ± 0.017	0.229CysGln: 0.229 ± 0.012	0.572CysArg: 0.572 ± 0.017	0.494CysSer: 0.494 ± 0.017	0.494CysThr: 0.494 ± 0.017	0.845CysVal: 0.845 ± 0.023	0.126CysTrp: 0.126 ± 0.008	0.213CysTyr: 0.213 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.764AspAla: 7.764 ± 0.091	0.437AspCys: 0.437 ± 0.017	3.129AspAsp: 3.129 ± 0.047	3.373AspGlu: 3.373 ± 0.05	1.983AspPhe: 1.983 ± 0.035	4.457AspGly: 4.457 ± 0.058	1.224AspHis: 1.224 ± 0.027	2.686AspIle: 2.686 ± 0.039	1.426AspLys: 1.426 ± 0.037	5.16AspLeu: 5.16 ± 0.064	1.201AspMet: 1.201 ± 0.024	1.369AspAsn: 1.369 ± 0.028	2.911AspPro: 2.911 ± 0.042	1.536AspGln: 1.536 ± 0.032	3.444AspArg: 3.444 ± 0.048	2.455AspSer: 2.455 ± 0.033	2.962AspThr: 2.962 ± 0.04	4.572AspVal: 4.572 ± 0.057	0.898AspTrp: 0.898 ± 0.024	1.464AspTyr: 1.464 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	6.504GluAla: 6.504 ± 0.082	0.411GluCys: 0.411 ± 0.019	2.119GluAsp: 2.119 ± 0.032	2.41GluGlu: 2.41 ± 0.046	1.713GluPhe: 1.713 ± 0.032	3.469GluGly: 3.469 ± 0.046	1.368GluHis: 1.368 ± 0.034	2.754GluIle: 2.754 ± 0.046	1.836GluLys: 1.836 ± 0.036	5.143GluLeu: 5.143 ± 0.063	1.185GluMet: 1.185 ± 0.024	1.434GluAsn: 1.434 ± 0.033	2.528GluPro: 2.528 ± 0.046	2.252GluGln: 2.252 ± 0.039	4.563GluArg: 4.563 ± 0.055	2.592GluSer: 2.592 ± 0.045	2.993GluThr: 2.993 ± 0.043	3.433GluVal: 3.433 ± 0.054	0.659GluTrp: 0.659 ± 0.019	1.12GluTyr: 1.12 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.752PheAla: 4.752 ± 0.056	0.436PheCys: 0.436 ± 0.016	2.707PheAsp: 2.707 ± 0.038	2.036PheGlu: 2.036 ± 0.039	1.522PhePhe: 1.522 ± 0.036	3.716PheGly: 3.716 ± 0.051	0.763PheHis: 0.763 ± 0.022	1.732PheIle: 1.732 ± 0.034	0.954PheLys: 0.954 ± 0.027	3.038PheLeu: 3.038 ± 0.047	0.842PheMet: 0.842 ± 0.019	1.221PheAsn: 1.221 ± 0.027	1.601PhePro: 1.601 ± 0.034	1.027PheGln: 1.027 ± 0.022	2.093PheArg: 2.093 ± 0.041	2.343PheSer: 2.343 ± 0.04	2.024PheThr: 2.024 ± 0.03	3.157PheVal: 3.157 ± 0.041	0.523PheTrp: 0.523 ± 0.018	1.004PheTyr: 1.004 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	9.548GlyAla: 9.548 ± 0.111	0.859GlyCys: 0.859 ± 0.021	4.052GlyAsp: 4.052 ± 0.05	4.273GlyGlu: 4.273 ± 0.053	3.476GlyPhe: 3.476 ± 0.048	6.897GlyGly: 6.897 ± 0.131	1.955GlyHis: 1.955 ± 0.034	4.394GlyIle: 4.394 ± 0.054	3.202GlyLys: 3.202 ± 0.053	8.069GlyLeu: 8.069 ± 0.079	2.283GlyMet: 2.283 ± 0.043	2.465GlyAsn: 2.465 ± 0.052	2.905GlyPro: 2.905 ± 0.051	2.735GlyGln: 2.735 ± 0.05	5.215GlyArg: 5.215 ± 0.063	4.673GlySer: 4.673 ± 0.073	4.895GlyThr: 4.895 ± 0.087	6.941GlyVal: 6.941 ± 0.077	1.303GlyTrp: 1.303 ± 0.031	2.379GlyTyr: 2.379 ± 0.034	0.0GlyXaa: 0.0 ± 0.0
His	3.174HisAla: 3.174 ± 0.045	0.252HisCys: 0.252 ± 0.013	1.464HisAsp: 1.464 ± 0.031	1.238HisGlu: 1.238 ± 0.03	0.978HisPhe: 0.978 ± 0.027	2.195HisGly: 2.195 ± 0.039	0.666HisHis: 0.666 ± 0.022	0.957HisIle: 0.957 ± 0.024	0.516HisLys: 0.516 ± 0.018	2.152HisLeu: 2.152 ± 0.042	0.515HisMet: 0.515 ± 0.018	0.578HisAsn: 0.578 ± 0.019	1.451HisPro: 1.451 ± 0.033	0.663HisGln: 0.663 ± 0.02	1.581HisArg: 1.581 ± 0.032	1.032HisSer: 1.032 ± 0.024	1.163HisThr: 1.163 ± 0.027	1.88HisVal: 1.88 ± 0.034	0.399HisTrp: 0.399 ± 0.014	0.667HisTyr: 0.667 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.047IleAla: 7.047 ± 0.071	0.458IleCys: 0.458 ± 0.016	3.518IleAsp: 3.518 ± 0.046	3.353IleGlu: 3.353 ± 0.043	1.526IlePhe: 1.526 ± 0.033	4.795IleGly: 4.795 ± 0.057	0.937IleHis: 0.937 ± 0.023	1.701IleIle: 1.701 ± 0.037	1.345IleLys: 1.345 ± 0.03	3.443IleLeu: 3.443 ± 0.046	0.779IleMet: 0.779 ± 0.024	1.45IleAsn: 1.45 ± 0.034	2.184IlePro: 2.184 ± 0.04	1.286IleGln: 1.286 ± 0.028	2.903IleArg: 2.903 ± 0.04	2.53IleSer: 2.53 ± 0.042	2.486IleThr: 2.486 ± 0.039	4.536IleVal: 4.536 ± 0.055	0.528IleTrp: 0.528 ± 0.017	1.06IleTyr: 1.06 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	3.495LysAla: 3.495 ± 0.058	0.16LysCys: 0.16 ± 0.009	1.565LysAsp: 1.565 ± 0.033	1.434LysGlu: 1.434 ± 0.033	0.878LysPhe: 0.878 ± 0.022	2.165LysGly: 2.165 ± 0.044	0.662LysHis: 0.662 ± 0.019	1.579LysIle: 1.579 ± 0.031	1.301LysLys: 1.301 ± 0.039	3.285LysLeu: 3.285 ± 0.05	0.791LysMet: 0.791 ± 0.024	0.899LysAsn: 0.899 ± 0.027	2.014LysPro: 2.014 ± 0.034	1.236LysGln: 1.236 ± 0.031	2.283LysArg: 2.283 ± 0.039	1.77LysSer: 1.77 ± 0.034	1.965LysThr: 1.965 ± 0.038	2.359LysVal: 2.359 ± 0.043	0.37LysTrp: 0.37 ± 0.015	0.688LysTyr: 0.688 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	13.601LeuAla: 13.601 ± 0.12	0.988LeuCys: 0.988 ± 0.022	5.953LeuAsp: 5.953 ± 0.065	4.907LeuGlu: 4.907 ± 0.061	3.635LeuPhe: 3.635 ± 0.047	8.0LeuGly: 8.0 ± 0.083	2.303LeuHis: 2.303 ± 0.044	4.733LeuIle: 4.733 ± 0.06	3.499LeuLys: 3.499 ± 0.052	9.911LeuLeu: 9.911 ± 0.112	2.3LeuMet: 2.3 ± 0.042	2.84LeuAsn: 2.84 ± 0.045	5.593LeuPro: 5.593 ± 0.059	3.209LeuGln: 3.209 ± 0.046	6.881LeuArg: 6.881 ± 0.077	6.165LeuSer: 6.165 ± 0.059	5.755LeuThr: 5.755 ± 0.065	7.643LeuVal: 7.643 ± 0.083	1.112LeuTrp: 1.112 ± 0.024	2.192LeuTyr: 2.192 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	2.521MetAla: 2.521 ± 0.04	0.187MetCys: 0.187 ± 0.011	0.986MetAsp: 0.986 ± 0.027	0.946MetGlu: 0.946 ± 0.022	0.784MetPhe: 0.784 ± 0.022	1.57MetGly: 1.57 ± 0.042	0.589MetHis: 0.589 ± 0.017	1.202MetIle: 1.202 ± 0.026	1.095MetLys: 1.095 ± 0.026	2.661MetLeu: 2.661 ± 0.036	0.626MetMet: 0.626 ± 0.02	0.993MetAsn: 0.993 ± 0.021	1.44MetPro: 1.44 ± 0.032	1.03MetGln: 1.03 ± 0.023	1.815MetArg: 1.815 ± 0.035	1.812MetSer: 1.812 ± 0.033	1.758MetThr: 1.758 ± 0.031	1.53MetVal: 1.53 ± 0.028	0.224MetTrp: 0.224 ± 0.012	0.438MetTyr: 0.438 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.676AsnAla: 3.676 ± 0.058	0.261AsnCys: 0.261 ± 0.013	1.471AsnAsp: 1.471 ± 0.033	1.365AsnGlu: 1.365 ± 0.031	1.013AsnPhe: 1.013 ± 0.029	2.613AsnGly: 2.613 ± 0.057	0.578AsnHis: 0.578 ± 0.018	1.267AsnIle: 1.267 ± 0.028	0.644AsnLys: 0.644 ± 0.021	2.811AsnLeu: 2.811 ± 0.044	0.588AsnMet: 0.588 ± 0.021	0.885AsnAsn: 0.885 ± 0.03	1.844AsnPro: 1.844 ± 0.034	0.915AsnGln: 0.915 ± 0.026	1.865AsnArg: 1.865 ± 0.031	1.354AsnSer: 1.354 ± 0.036	1.606AsnThr: 1.606 ± 0.039	2.366AsnVal: 2.366 ± 0.043	0.431AsnTrp: 0.431 ± 0.017	0.72AsnTyr: 0.72 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	6.736ProAla: 6.736 ± 0.086	0.347ProCys: 0.347 ± 0.015	3.446ProAsp: 3.446 ± 0.048	3.033ProGlu: 3.033 ± 0.045	1.976ProPhe: 1.976 ± 0.039	4.333ProGly: 4.333 ± 0.06	1.265ProHis: 1.265 ± 0.029	1.767ProIle: 1.767 ± 0.035	1.426ProLys: 1.426 ± 0.031	5.071ProLeu: 5.071 ± 0.051	1.137ProMet: 1.137 ± 0.024	1.304ProAsn: 1.304 ± 0.029	2.396ProPro: 2.396 ± 0.054	1.795ProGln: 1.795 ± 0.041	2.921ProArg: 2.921 ± 0.044	2.711ProSer: 2.711 ± 0.042	2.45ProThr: 2.45 ± 0.04	4.78ProVal: 4.78 ± 0.052	0.639ProTrp: 0.639 ± 0.02	1.22ProTyr: 1.22 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	4.209GlnAla: 4.209 ± 0.054	0.267GlnCys: 0.267 ± 0.013	1.404GlnAsp: 1.404 ± 0.029	1.281GlnGlu: 1.281 ± 0.035	1.284GlnPhe: 1.284 ± 0.029	2.393GlnGly: 2.393 ± 0.039	0.961GlnHis: 0.961 ± 0.023	1.911GlnIle: 1.911 ± 0.031	1.16GlnLys: 1.16 ± 0.029	3.695GlnLeu: 3.695 ± 0.052	1.053GlnMet: 1.053 ± 0.028	0.927GlnAsn: 0.927 ± 0.027	2.021GlnPro: 2.021 ± 0.044	1.853GlnGln: 1.853 ± 0.037	2.819GlnArg: 2.819 ± 0.045	1.968GlnSer: 1.968 ± 0.035	1.99GlnThr: 1.99 ± 0.038	2.537GlnVal: 2.537 ± 0.042	0.53GlnTrp: 0.53 ± 0.019	0.925GlnTyr: 0.925 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	8.185ArgAla: 8.185 ± 0.087	0.583ArgCys: 0.583 ± 0.019	3.926ArgAsp: 3.926 ± 0.05	4.146ArgGlu: 4.146 ± 0.064	3.024ArgPhe: 3.024 ± 0.049	4.638ArgGly: 4.638 ± 0.049	1.905ArgHis: 1.905 ± 0.034	3.701ArgIle: 3.701 ± 0.055	2.037ArgLys: 2.037 ± 0.042	6.957ArgLeu: 6.957 ± 0.073	1.873ArgMet: 1.873 ± 0.033	1.939ArgAsn: 1.939 ± 0.038	3.025ArgPro: 3.025 ± 0.05	2.492ArgGln: 2.492 ± 0.049	5.254ArgArg: 5.254 ± 0.063	3.388ArgSer: 3.388 ± 0.046	3.539ArgThr: 3.539 ± 0.049	5.315ArgVal: 5.315 ± 0.056	1.008ArgTrp: 1.008 ± 0.025	1.985ArgTyr: 1.985 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	6.749SerAla: 6.749 ± 0.081	0.471SerCys: 0.471 ± 0.02	2.724SerAsp: 2.724 ± 0.04	2.428SerGlu: 2.428 ± 0.04	2.153SerPhe: 2.153 ± 0.035	5.493SerGly: 5.493 ± 0.069	1.269SerHis: 1.269 ± 0.028	2.849SerIle: 2.849 ± 0.045	1.667SerLys: 1.667 ± 0.032	5.727SerLeu: 5.727 ± 0.064	1.467SerMet: 1.467 ± 0.03	1.622SerAsn: 1.622 ± 0.031	2.861SerPro: 2.861 ± 0.041	1.849SerGln: 1.849 ± 0.037	3.72SerArg: 3.72 ± 0.052	3.456SerSer: 3.456 ± 0.055	3.284SerThr: 3.284 ± 0.065	4.457SerVal: 4.457 ± 0.054	0.698SerTrp: 0.698 ± 0.021	1.276SerTyr: 1.276 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.134ThrAla: 6.134 ± 0.091	0.457ThrCys: 0.457 ± 0.015	2.729ThrAsp: 2.729 ± 0.04	2.302ThrGlu: 2.302 ± 0.041	2.138ThrPhe: 2.138 ± 0.037	5.326ThrGly: 5.326 ± 0.07	1.322ThrHis: 1.322 ± 0.027	2.709ThrIle: 2.709 ± 0.042	1.291ThrLys: 1.291 ± 0.031	6.723ThrLeu: 6.723 ± 0.074	1.301ThrMet: 1.301 ± 0.028	1.415ThrAsn: 1.415 ± 0.041	3.672ThrPro: 3.672 ± 0.05	2.071ThrGln: 2.071 ± 0.036	3.679ThrArg: 3.679 ± 0.049	3.041ThrSer: 3.041 ± 0.051	3.161ThrThr: 3.161 ± 0.059	4.558ThrVal: 4.558 ± 0.051	0.77ThrTrp: 0.77 ± 0.023	1.284ThrTyr: 1.284 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	9.935ValAla: 9.935 ± 0.08	0.838ValCys: 0.838 ± 0.024	4.39ValAsp: 4.39 ± 0.052	4.208ValGlu: 4.208 ± 0.052	2.942ValPhe: 2.942 ± 0.04	5.655ValGly: 5.655 ± 0.066	1.619ValHis: 1.619 ± 0.031	3.987ValIle: 3.987 ± 0.056	2.557ValLys: 2.557 ± 0.05	8.086ValLeu: 8.086 ± 0.085	1.947ValMet: 1.947 ± 0.033	2.318ValAsn: 2.318 ± 0.044	4.108ValPro: 4.108 ± 0.049	2.482ValGln: 2.482 ± 0.037	5.159ValArg: 5.159 ± 0.055	4.857ValSer: 4.857 ± 0.056	4.764ValThr: 4.764 ± 0.064	6.505ValVal: 6.505 ± 0.075	0.986ValTrp: 0.986 ± 0.029	1.736ValTyr: 1.736 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.135TrpAla: 1.135 ± 0.028	0.148TrpCys: 0.148 ± 0.009	0.587TrpAsp: 0.587 ± 0.019	0.51TrpGlu: 0.51 ± 0.016	0.578TrpPhe: 0.578 ± 0.02	0.848TrpGly: 0.848 ± 0.024	0.399TrpHis: 0.399 ± 0.017	0.752TrpIle: 0.752 ± 0.024	0.437TrpLys: 0.437 ± 0.016	1.923TrpLeu: 1.923 ± 0.043	0.387TrpMet: 0.387 ± 0.015	0.462TrpAsn: 0.462 ± 0.017	0.676TrpPro: 0.676 ± 0.019	0.645TrpGln: 0.645 ± 0.021	1.148TrpArg: 1.148 ± 0.03	0.787TrpSer: 0.787 ± 0.02	0.697TrpThr: 0.697 ± 0.024	0.892TrpVal: 0.892 ± 0.025	0.218TrpTrp: 0.218 ± 0.013	0.317TrpTyr: 0.317 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.734TyrAla: 2.734 ± 0.045	0.245TyrCys: 0.245 ± 0.012	1.362TyrAsp: 1.362 ± 0.029	1.195TyrGlu: 1.195 ± 0.027	1.045TyrPhe: 1.045 ± 0.027	2.134TyrGly: 2.134 ± 0.039	0.537TyrHis: 0.537 ± 0.019	0.884TyrIle: 0.884 ± 0.026	0.595TyrLys: 0.595 ± 0.02	2.476TyrLeu: 2.476 ± 0.044	0.454TyrMet: 0.454 ± 0.015	0.657TyrAsn: 0.657 ± 0.02	1.28TyrPro: 1.28 ± 0.028	0.837TyrGln: 0.837 ± 0.022	1.944TyrArg: 1.944 ± 0.033	1.239TyrSer: 1.239 ± 0.03	1.349TyrThr: 1.349 ± 0.033	1.951TyrVal: 1.951 ± 0.034	0.364TyrTrp: 0.364 ± 0.014	0.656TyrTyr: 0.656 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5332 proteins (1708161 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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