Amino acid dipepetide frequency for Macaca mulatta feces associated virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.412AlaAla: 4.412 ± 2.731
1.471AlaCys: 1.471 ± 0.91
7.353AlaAsp: 7.353 ± 1.907
2.941AlaGlu: 2.941 ± 0.332
0.0AlaPhe: 0.0 ± 0.0
8.824AlaGly: 8.824 ± 1.156
1.471AlaHis: 1.471 ± 1.243
5.882AlaIle: 5.882 ± 0.665
4.412AlaLys: 4.412 ± 0.578
1.471AlaLeu: 1.471 ± 1.243
5.882AlaMet: 5.882 ± 1.146
0.0AlaAsn: 0.0 ± 0.0
4.412AlaPro: 4.412 ± 2.731
4.412AlaGln: 4.412 ± 0.578
1.471AlaArg: 1.471 ± 0.91
4.412AlaSer: 4.412 ± 0.578
4.412AlaThr: 4.412 ± 2.731
5.882AlaVal: 5.882 ± 1.488
1.471AlaTrp: 1.471 ± 1.243
2.941AlaTyr: 2.941 ± 0.332
0.0AlaXaa: 0.0 ± 0.0
Cys
1.471CysAla: 1.471 ± 0.91
0.0CysCys: 0.0 ± 0.0
1.471CysAsp: 1.471 ± 0.91
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.471CysArg: 1.471 ± 1.243
1.471CysSer: 1.471 ± 1.243
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.882AspAla: 5.882 ± 3.641
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
0.0AspGlu: 0.0 ± 0.0
1.471AspPhe: 1.471 ± 0.91
4.412AspGly: 4.412 ± 1.575
0.0AspHis: 0.0 ± 0.0
5.882AspIle: 5.882 ± 2.818
2.941AspLys: 2.941 ± 2.485
1.471AspLeu: 1.471 ± 0.91
1.471AspMet: 1.471 ± 0.91
1.471AspAsn: 1.471 ± 0.91
4.412AspPro: 4.412 ± 0.578
2.941AspGln: 2.941 ± 0.332
5.882AspArg: 5.882 ± 2.818
4.412AspSer: 4.412 ± 0.578
7.353AspThr: 7.353 ± 0.245
5.882AspVal: 5.882 ± 1.488
0.0AspTrp: 0.0 ± 0.0
1.471AspTyr: 1.471 ± 0.91
0.0AspXaa: 0.0 ± 0.0
Glu
7.353GluAla: 7.353 ± 1.907
1.471GluCys: 1.471 ± 1.243
0.0GluAsp: 0.0 ± 0.0
4.412GluGlu: 4.412 ± 3.728
1.471GluPhe: 1.471 ± 0.91
10.294GluGly: 10.294 ± 0.087
1.471GluHis: 1.471 ± 1.243
0.0GluIle: 0.0 ± 0.0
2.941GluLys: 2.941 ± 0.332
5.882GluLeu: 5.882 ± 2.818
0.0GluMet: 0.0 ± 0.0
1.471GluAsn: 1.471 ± 1.243
0.0GluPro: 0.0 ± 0.0
1.471GluGln: 1.471 ± 1.243
5.882GluArg: 5.882 ± 2.818
1.471GluSer: 1.471 ± 0.91
5.882GluThr: 5.882 ± 0.665
1.471GluVal: 1.471 ± 1.243
0.0GluTrp: 0.0 ± 0.0
1.471GluTyr: 1.471 ± 1.243
0.0GluXaa: 0.0 ± 0.0
Phe
2.941PheAla: 2.941 ± 2.485
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
1.471PheGlu: 1.471 ± 1.243
0.0PhePhe: 0.0 ± 0.0
7.353PheGly: 7.353 ± 0.245
0.0PheHis: 0.0 ± 0.0
1.471PheIle: 1.471 ± 0.91
4.412PheLys: 4.412 ± 2.731
1.471PheLeu: 1.471 ± 0.91
0.0PheMet: 0.0 ± 0.0
2.941PheAsn: 2.941 ± 1.82
1.471PhePro: 1.471 ± 1.243
1.471PheGln: 1.471 ± 0.91
2.941PheArg: 2.941 ± 0.332
2.941PheSer: 2.941 ± 0.332
0.0PheThr: 0.0 ± 0.0
0.0PheVal: 0.0 ± 0.0
1.471PheTrp: 1.471 ± 0.91
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
10.294GlyAla: 10.294 ± 2.066
0.0GlyCys: 0.0 ± 0.0
4.412GlyAsp: 4.412 ± 2.731
0.0GlyGlu: 0.0 ± 0.0
1.471GlyPhe: 1.471 ± 1.243
4.412GlyGly: 4.412 ± 1.575
0.0GlyHis: 0.0 ± 0.0
4.412GlyIle: 4.412 ± 2.731
14.706GlyLys: 14.706 ± 5.968
13.235GlyLeu: 13.235 ± 3.886
1.471GlyMet: 1.471 ± 0.91
2.941GlyAsn: 2.941 ± 0.332
1.471GlyPro: 1.471 ± 1.243
2.941GlyGln: 2.941 ± 1.82
2.941GlyArg: 2.941 ± 1.82
10.294GlySer: 10.294 ± 4.219
4.412GlyThr: 4.412 ± 0.578
7.353GlyVal: 7.353 ± 0.245
2.941GlyTrp: 2.941 ± 0.332
2.941GlyTyr: 2.941 ± 2.485
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.471HisGly: 1.471 ± 1.243
0.0HisHis: 0.0 ± 0.0
1.471HisIle: 1.471 ± 1.243
1.471HisLys: 1.471 ± 1.243
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
1.471HisThr: 1.471 ± 0.91
0.0HisVal: 0.0 ± 0.0
1.471HisTrp: 1.471 ± 1.243
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.882IleAla: 5.882 ± 1.488
0.0IleCys: 0.0 ± 0.0
2.941IleAsp: 2.941 ± 0.332
8.824IleGlu: 8.824 ± 3.15
2.941IlePhe: 2.941 ± 0.332
5.882IleGly: 5.882 ± 3.641
4.412IleHis: 4.412 ± 1.575
4.412IleIle: 4.412 ± 3.728
5.882IleLys: 5.882 ± 0.665
1.471IleLeu: 1.471 ± 0.91
1.471IleMet: 1.471 ± 0.91
1.471IleAsn: 1.471 ± 0.91
2.941IlePro: 2.941 ± 2.485
2.941IleGln: 2.941 ± 0.332
1.471IleArg: 1.471 ± 1.243
0.0IleSer: 0.0 ± 0.0
2.941IleThr: 2.941 ± 0.332
7.353IleVal: 7.353 ± 0.245
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.412LysAla: 4.412 ± 0.578
0.0LysCys: 0.0 ± 0.0
4.412LysAsp: 4.412 ± 1.575
1.471LysGlu: 1.471 ± 1.243
4.412LysPhe: 4.412 ± 2.731
4.412LysGly: 4.412 ± 1.575
0.0LysHis: 0.0 ± 0.0
5.882LysIle: 5.882 ± 0.665
0.0LysLys: 0.0 ± 0.0
5.882LysLeu: 5.882 ± 2.818
1.471LysMet: 1.471 ± 0.91
4.412LysAsn: 4.412 ± 1.575
0.0LysPro: 0.0 ± 0.0
0.0LysGln: 0.0 ± 0.0
1.471LysArg: 1.471 ± 1.243
5.882LysSer: 5.882 ± 1.488
4.412LysThr: 4.412 ± 1.575
4.412LysVal: 4.412 ± 1.575
4.412LysTrp: 4.412 ± 3.728
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
2.941LeuAla: 2.941 ± 0.332
0.0LeuCys: 0.0 ± 0.0
1.471LeuAsp: 1.471 ± 1.243
1.471LeuGlu: 1.471 ± 1.243
1.471LeuPhe: 1.471 ± 1.243
1.471LeuGly: 1.471 ± 1.243
0.0LeuHis: 0.0 ± 0.0
2.941LeuIle: 2.941 ± 0.332
2.941LeuLys: 2.941 ± 2.485
1.471LeuLeu: 1.471 ± 0.91
0.0LeuMet: 0.0 ± 0.0
2.941LeuAsn: 2.941 ± 1.82
5.882LeuPro: 5.882 ± 3.641
5.882LeuGln: 5.882 ± 3.641
2.941LeuArg: 2.941 ± 0.332
7.353LeuSer: 7.353 ± 0.245
8.824LeuThr: 8.824 ± 5.303
5.882LeuVal: 5.882 ± 3.641
0.0LeuTrp: 0.0 ± 0.0
4.412LeuTyr: 4.412 ± 0.578
0.0LeuXaa: 0.0 ± 0.0
Met
1.471MetAla: 1.471 ± 0.91
0.0MetCys: 0.0 ± 0.0
2.941MetAsp: 2.941 ± 0.332
1.471MetGlu: 1.471 ± 0.91
1.471MetPhe: 1.471 ± 0.91
2.941MetGly: 2.941 ± 0.332
0.0MetHis: 0.0 ± 0.0
1.471MetIle: 1.471 ± 0.91
0.0MetLys: 0.0 ± 0.0
4.412MetLeu: 4.412 ± 0.578
0.0MetMet: 0.0 ± 0.0
1.471MetAsn: 1.471 ± 0.91
4.412MetPro: 4.412 ± 0.578
0.0MetGln: 0.0 ± 0.0
4.412MetArg: 4.412 ± 1.575
0.0MetSer: 0.0 ± 0.0
1.471MetThr: 1.471 ± 1.243
1.471MetVal: 1.471 ± 0.91
2.941MetTrp: 2.941 ± 0.332
1.471MetTyr: 1.471 ± 0.91
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
10.294AsnAsp: 10.294 ± 2.24
1.471AsnGlu: 1.471 ± 0.91
1.471AsnPhe: 1.471 ± 0.91
2.941AsnGly: 2.941 ± 0.332
0.0AsnHis: 0.0 ± 0.0
2.941AsnIle: 2.941 ± 2.485
2.941AsnLys: 2.941 ± 0.332
1.471AsnLeu: 1.471 ± 0.91
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
2.941AsnPro: 2.941 ± 1.82
2.941AsnGln: 2.941 ± 1.82
0.0AsnArg: 0.0 ± 0.0
1.471AsnSer: 1.471 ± 0.91
5.882AsnThr: 5.882 ± 1.488
4.412AsnVal: 4.412 ± 2.731
1.471AsnTrp: 1.471 ± 0.91
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.412ProAla: 4.412 ± 2.731
0.0ProCys: 0.0 ± 0.0
1.471ProAsp: 1.471 ± 0.91
2.941ProGlu: 2.941 ± 0.332
0.0ProPhe: 0.0 ± 0.0
1.471ProGly: 1.471 ± 0.91
0.0ProHis: 0.0 ± 0.0
2.941ProIle: 2.941 ± 1.82
2.941ProLys: 2.941 ± 0.332
5.882ProLeu: 5.882 ± 0.665
1.471ProMet: 1.471 ± 0.91
0.0ProAsn: 0.0 ± 0.0
5.882ProPro: 5.882 ± 0.665
2.941ProGln: 2.941 ± 1.82
4.412ProArg: 4.412 ± 3.728
2.941ProSer: 2.941 ± 1.82
4.412ProThr: 4.412 ± 1.575
1.471ProVal: 1.471 ± 0.91
1.471ProTrp: 1.471 ± 0.91
1.471ProTyr: 1.471 ± 1.243
0.0ProXaa: 0.0 ± 0.0
Gln
1.471GlnAla: 1.471 ± 0.91
1.471GlnCys: 1.471 ± 1.243
2.941GlnAsp: 2.941 ± 1.82
2.941GlnGlu: 2.941 ± 2.485
4.412GlnPhe: 4.412 ± 0.578
2.941GlnGly: 2.941 ± 1.82
0.0GlnHis: 0.0 ± 0.0
1.471GlnIle: 1.471 ± 0.91
1.471GlnLys: 1.471 ± 1.243
2.941GlnLeu: 2.941 ± 1.82
2.941GlnMet: 2.941 ± 0.332
1.471GlnAsn: 1.471 ± 0.91
1.471GlnPro: 1.471 ± 0.91
2.941GlnGln: 2.941 ± 2.485
1.471GlnArg: 1.471 ± 1.243
5.882GlnSer: 5.882 ± 3.641
0.0GlnThr: 0.0 ± 0.0
1.471GlnVal: 1.471 ± 0.91
0.0GlnTrp: 0.0 ± 0.0
2.941GlnTyr: 2.941 ± 1.82
0.0GlnXaa: 0.0 ± 0.0
Arg
4.412ArgAla: 4.412 ± 1.575
0.0ArgCys: 0.0 ± 0.0
1.471ArgAsp: 1.471 ± 1.243
5.882ArgGlu: 5.882 ± 4.971
4.412ArgPhe: 4.412 ± 1.575
4.412ArgGly: 4.412 ± 1.575
0.0ArgHis: 0.0 ± 0.0
4.412ArgIle: 4.412 ± 1.575
2.941ArgLys: 2.941 ± 0.332
0.0ArgLeu: 0.0 ± 0.0
1.471ArgMet: 1.471 ± 0.91
1.471ArgAsn: 1.471 ± 1.243
4.412ArgPro: 4.412 ± 1.575
1.471ArgGln: 1.471 ± 0.91
2.941ArgArg: 2.941 ± 2.485
2.941ArgSer: 2.941 ± 0.332
0.0ArgThr: 0.0 ± 0.0
7.353ArgVal: 7.353 ± 0.245
1.471ArgTrp: 1.471 ± 1.243
4.412ArgTyr: 4.412 ± 1.575
0.0ArgXaa: 0.0 ± 0.0
Ser
2.941SerAla: 2.941 ± 0.332
1.471SerCys: 1.471 ± 0.91
8.824SerAsp: 8.824 ± 3.308
5.882SerGlu: 5.882 ± 0.665
1.471SerPhe: 1.471 ± 0.91
11.765SerGly: 11.765 ± 2.976
0.0SerHis: 0.0 ± 0.0
2.941SerIle: 2.941 ± 1.82
1.471SerLys: 1.471 ± 0.91
1.471SerLeu: 1.471 ± 0.91
4.412SerMet: 4.412 ± 2.181
8.824SerAsn: 8.824 ± 3.308
0.0SerPro: 0.0 ± 0.0
1.471SerGln: 1.471 ± 0.91
1.471SerArg: 1.471 ± 1.243
2.941SerSer: 2.941 ± 0.332
4.412SerThr: 4.412 ± 2.731
4.412SerVal: 4.412 ± 0.578
1.471SerTrp: 1.471 ± 1.243
2.941SerTyr: 2.941 ± 1.82
0.0SerXaa: 0.0 ± 0.0
Thr
5.882ThrAla: 5.882 ± 0.665
0.0ThrCys: 0.0 ± 0.0
1.471ThrAsp: 1.471 ± 0.91
2.941ThrGlu: 2.941 ± 1.82
1.471ThrPhe: 1.471 ± 0.91
5.882ThrGly: 5.882 ± 0.665
0.0ThrHis: 0.0 ± 0.0
5.882ThrIle: 5.882 ± 0.665
1.471ThrLys: 1.471 ± 0.91
4.412ThrLeu: 4.412 ± 0.578
4.412ThrMet: 4.412 ± 1.575
5.882ThrAsn: 5.882 ± 0.665
5.882ThrPro: 5.882 ± 0.665
2.941ThrGln: 2.941 ± 0.332
1.471ThrArg: 1.471 ± 0.91
5.882ThrSer: 5.882 ± 1.488
0.0ThrThr: 0.0 ± 0.0
0.0ThrVal: 0.0 ± 0.0
2.941ThrTrp: 2.941 ± 0.332
5.882ThrTyr: 5.882 ± 2.818
0.0ThrXaa: 0.0 ± 0.0
Val
2.941ValAla: 2.941 ± 0.332
0.0ValCys: 0.0 ± 0.0
1.471ValAsp: 1.471 ± 0.91
4.412ValGlu: 4.412 ± 2.731
1.471ValPhe: 1.471 ± 0.91
7.353ValGly: 7.353 ± 4.551
0.0ValHis: 0.0 ± 0.0
4.412ValIle: 4.412 ± 1.575
1.471ValLys: 1.471 ± 1.243
4.412ValLeu: 4.412 ± 1.575
4.412ValMet: 4.412 ± 1.575
4.412ValAsn: 4.412 ± 0.578
1.471ValPro: 1.471 ± 0.91
1.471ValGln: 1.471 ± 1.243
4.412ValArg: 4.412 ± 0.578
8.824ValSer: 8.824 ± 5.461
2.941ValThr: 2.941 ± 1.82
7.353ValVal: 7.353 ± 0.245
1.471ValTrp: 1.471 ± 1.243
4.412ValTyr: 4.412 ± 0.578
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.471TrpAsp: 1.471 ± 1.243
1.471TrpGlu: 1.471 ± 1.243
1.471TrpPhe: 1.471 ± 1.243
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.471TrpIle: 1.471 ± 0.91
1.471TrpLys: 1.471 ± 1.243
1.471TrpLeu: 1.471 ± 1.243
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.471TrpPro: 1.471 ± 0.91
2.941TrpGln: 2.941 ± 0.332
4.412TrpArg: 4.412 ± 1.575
1.471TrpSer: 1.471 ± 0.91
4.412TrpThr: 4.412 ± 1.575
1.471TrpVal: 1.471 ± 1.243
0.0TrpTrp: 0.0 ± 0.0
1.471TrpTyr: 1.471 ± 1.243
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.412TyrAla: 4.412 ± 0.578
0.0TyrCys: 0.0 ± 0.0
2.941TyrAsp: 2.941 ± 0.332
4.412TyrGlu: 4.412 ± 3.728
1.471TyrPhe: 1.471 ± 1.243
4.412TyrGly: 4.412 ± 2.731
0.0TyrHis: 0.0 ± 0.0
2.941TyrIle: 2.941 ± 0.332
1.471TyrLys: 1.471 ± 0.91
1.471TyrLeu: 1.471 ± 1.243
1.471TyrMet: 1.471 ± 1.243
1.471TyrAsn: 1.471 ± 0.91
0.0TyrPro: 0.0 ± 0.0
1.471TyrGln: 1.471 ± 0.91
4.412TyrArg: 4.412 ± 1.575
1.471TyrSer: 1.471 ± 1.243
1.471TyrThr: 1.471 ± 0.91
1.471TyrVal: 1.471 ± 0.91
1.471TyrTrp: 1.471 ± 1.243
2.941TyrTyr: 2.941 ± 1.82
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (681 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski