Amino acid dipepetide frequency for Oleibacter marinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.559AlaAla: 9.559 ± 0.114	0.975AlaCys: 0.975 ± 0.026	6.211AlaAsp: 6.211 ± 0.12	6.983AlaGlu: 6.983 ± 0.103	3.417AlaPhe: 3.417 ± 0.059	7.506AlaGly: 7.506 ± 0.106	1.717AlaHis: 1.717 ± 0.043	5.216AlaIle: 5.216 ± 0.073	3.407AlaLys: 3.407 ± 0.064	10.463AlaLeu: 10.463 ± 0.127	2.711AlaMet: 2.711 ± 0.055	3.143AlaAsn: 3.143 ± 0.093	3.593AlaPro: 3.593 ± 0.074	3.387AlaGln: 3.387 ± 0.063	4.905AlaArg: 4.905 ± 0.077	6.15AlaSer: 6.15 ± 0.081	4.971AlaThr: 4.971 ± 0.073	6.568AlaVal: 6.568 ± 0.092	1.068AlaTrp: 1.068 ± 0.034	2.303AlaTyr: 2.303 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.779CysAla: 0.779 ± 0.025	0.113CysCys: 0.113 ± 0.01	0.673CysAsp: 0.673 ± 0.025	0.575CysGlu: 0.575 ± 0.021	0.341CysPhe: 0.341 ± 0.017	0.845CysGly: 0.845 ± 0.03	0.285CysHis: 0.285 ± 0.015	0.525CysIle: 0.525 ± 0.022	0.345CysLys: 0.345 ± 0.018	0.909CysLeu: 0.909 ± 0.031	0.198CysMet: 0.198 ± 0.013	0.307CysAsn: 0.307 ± 0.017	0.455CysPro: 0.455 ± 0.023	0.367CysGln: 0.367 ± 0.018	0.526CysArg: 0.526 ± 0.023	0.643CysSer: 0.643 ± 0.026	0.432CysThr: 0.432 ± 0.02	0.601CysVal: 0.601 ± 0.023	0.115CysTrp: 0.115 ± 0.011	0.281CysTyr: 0.281 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	5.826AspAla: 5.826 ± 0.108	0.563AspCys: 0.563 ± 0.024	4.364AspAsp: 4.364 ± 0.132	4.498AspGlu: 4.498 ± 0.071	2.556AspPhe: 2.556 ± 0.05	5.265AspGly: 5.265 ± 0.272	1.347AspHis: 1.347 ± 0.038	4.087AspIle: 4.087 ± 0.068	2.448AspLys: 2.448 ± 0.047	6.058AspLeu: 6.058 ± 0.095	1.642AspMet: 1.642 ± 0.045	2.478AspAsn: 2.478 ± 0.103	2.578AspPro: 2.578 ± 0.079	2.284AspGln: 2.284 ± 0.043	3.019AspArg: 3.019 ± 0.057	4.0AspSer: 4.0 ± 0.094	3.52AspThr: 3.52 ± 0.119	4.601AspVal: 4.601 ± 0.073	0.986AspTrp: 0.986 ± 0.027	2.054AspTyr: 2.054 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	6.518GluAla: 6.518 ± 0.084	0.578GluCys: 0.578 ± 0.023	3.653GluAsp: 3.653 ± 0.061	4.708GluGlu: 4.708 ± 0.075	2.507GluPhe: 2.507 ± 0.053	4.456GluGly: 4.456 ± 0.067	1.605GluHis: 1.605 ± 0.039	3.737GluIle: 3.737 ± 0.06	3.361GluLys: 3.361 ± 0.064	7.129GluLeu: 7.129 ± 0.089	1.614GluMet: 1.614 ± 0.042	2.583GluAsn: 2.583 ± 0.051	2.396GluPro: 2.396 ± 0.046	3.482GluGln: 3.482 ± 0.069	4.337GluArg: 4.337 ± 0.071	4.101GluSer: 4.101 ± 0.072	3.5GluThr: 3.5 ± 0.068	4.656GluVal: 4.656 ± 0.074	0.938GluTrp: 0.938 ± 0.031	2.018GluTyr: 2.018 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	3.261PheAla: 3.261 ± 0.057	0.436PheCys: 0.436 ± 0.022	2.697PheAsp: 2.697 ± 0.061	2.3PheGlu: 2.3 ± 0.046	1.562PhePhe: 1.562 ± 0.041	2.893PheGly: 2.893 ± 0.05	0.734PheHis: 0.734 ± 0.028	2.096PheIle: 2.096 ± 0.046	1.359PheLys: 1.359 ± 0.037	3.129PheLeu: 3.129 ± 0.063	0.961PheMet: 0.961 ± 0.031	1.643PheAsn: 1.643 ± 0.042	1.462PhePro: 1.462 ± 0.033	1.13PheGln: 1.13 ± 0.031	2.15PheArg: 2.15 ± 0.044	3.187PheSer: 3.187 ± 0.063	2.291PheThr: 2.291 ± 0.064	2.412PheVal: 2.412 ± 0.05	0.557PheTrp: 0.557 ± 0.025	1.217PheTyr: 1.217 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	6.115GlyAla: 6.115 ± 0.102	0.84GlyCys: 0.84 ± 0.028	4.766GlyAsp: 4.766 ± 0.13	4.782GlyGlu: 4.782 ± 0.08	3.125GlyPhe: 3.125 ± 0.058	5.102GlyGly: 5.102 ± 0.088	1.527GlyHis: 1.527 ± 0.037	4.722GlyIle: 4.722 ± 0.093	3.427GlyLys: 3.427 ± 0.061	7.075GlyLeu: 7.075 ± 0.084	2.111GlyMet: 2.111 ± 0.048	2.773GlyAsn: 2.773 ± 0.073	1.974GlyPro: 1.974 ± 0.046	2.794GlyGln: 2.794 ± 0.052	3.858GlyArg: 3.858 ± 0.067	4.702GlySer: 4.702 ± 0.073	4.104GlyThr: 4.104 ± 0.117	5.52GlyVal: 5.52 ± 0.091	1.105GlyTrp: 1.105 ± 0.034	2.564GlyTyr: 2.564 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.591HisAla: 1.591 ± 0.037	0.283HisCys: 0.283 ± 0.014	1.132HisAsp: 1.132 ± 0.032	1.211HisGlu: 1.211 ± 0.032	0.914HisPhe: 0.914 ± 0.028	1.513HisGly: 1.513 ± 0.037	0.624HisHis: 0.624 ± 0.024	1.191HisIle: 1.191 ± 0.032	0.828HisLys: 0.828 ± 0.029	2.196HisLeu: 2.196 ± 0.049	0.532HisMet: 0.532 ± 0.021	0.691HisAsn: 0.691 ± 0.026	1.206HisPro: 1.206 ± 0.034	0.902HisGln: 0.902 ± 0.028	1.249HisArg: 1.249 ± 0.036	1.369HisSer: 1.369 ± 0.041	1.013HisThr: 1.013 ± 0.029	1.214HisVal: 1.214 ± 0.03	0.428HisTrp: 0.428 ± 0.021	0.736HisTyr: 0.736 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	5.784IleAla: 5.784 ± 0.074	0.544IleCys: 0.544 ± 0.024	4.092IleAsp: 4.092 ± 0.074	4.164IleGlu: 4.164 ± 0.068	1.827IlePhe: 1.827 ± 0.046	3.996IleGly: 3.996 ± 0.068	1.09IleHis: 1.09 ± 0.034	2.799IleIle: 2.799 ± 0.054	2.216IleLys: 2.216 ± 0.051	4.626IleLeu: 4.626 ± 0.076	1.126IleMet: 1.126 ± 0.031	2.527IleAsn: 2.527 ± 0.053	2.722IlePro: 2.722 ± 0.057	1.946IleGln: 1.946 ± 0.042	3.437IleArg: 3.437 ± 0.064	4.165IleSer: 4.165 ± 0.065	3.307IleThr: 3.307 ± 0.062	3.505IleVal: 3.505 ± 0.056	0.614IleTrp: 0.614 ± 0.024	1.439IleTyr: 1.439 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.33LysAla: 4.33 ± 0.081	0.256LysCys: 0.256 ± 0.018	2.401LysAsp: 2.401 ± 0.054	2.834LysGlu: 2.834 ± 0.059	1.118LysPhe: 1.118 ± 0.035	2.811LysGly: 2.811 ± 0.051	0.905LysHis: 0.905 ± 0.03	2.111LysIle: 2.111 ± 0.043	2.226LysLys: 2.226 ± 0.057	3.89LysLeu: 3.89 ± 0.071	0.964LysMet: 0.964 ± 0.032	1.58LysAsn: 1.58 ± 0.039	1.969LysPro: 1.969 ± 0.054	1.796LysGln: 1.796 ± 0.046	2.475LysArg: 2.475 ± 0.048	2.552LysSer: 2.552 ± 0.051	2.228LysThr: 2.228 ± 0.041	2.965LysVal: 2.965 ± 0.054	0.418LysTrp: 0.418 ± 0.021	1.089LysTyr: 1.089 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	9.84LeuAla: 9.84 ± 0.119	0.955LeuCys: 0.955 ± 0.03	5.899LeuAsp: 5.899 ± 0.086	6.251LeuGlu: 6.251 ± 0.079	3.583LeuPhe: 3.583 ± 0.072	6.674LeuGly: 6.674 ± 0.078	2.013LeuHis: 2.013 ± 0.046	5.817LeuIle: 5.817 ± 0.09	4.681LeuLys: 4.681 ± 0.069	10.105LeuLeu: 10.105 ± 0.151	2.739LeuMet: 2.739 ± 0.052	4.309LeuAsn: 4.309 ± 0.06	4.961LeuPro: 4.961 ± 0.081	3.632LeuGln: 3.632 ± 0.065	5.601LeuArg: 5.601 ± 0.087	7.706LeuSer: 7.706 ± 0.082	6.313LeuThr: 6.313 ± 0.134	6.595LeuVal: 6.595 ± 0.087	1.187LeuTrp: 1.187 ± 0.031	2.499LeuTyr: 2.499 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.637MetAla: 2.637 ± 0.054	0.167MetCys: 0.167 ± 0.011	1.337MetAsp: 1.337 ± 0.04	1.381MetGlu: 1.381 ± 0.031	0.814MetPhe: 0.814 ± 0.029	1.729MetGly: 1.729 ± 0.041	0.522MetHis: 0.522 ± 0.024	1.318MetIle: 1.318 ± 0.035	1.354MetLys: 1.354 ± 0.04	2.551MetLeu: 2.551 ± 0.05	0.749MetMet: 0.749 ± 0.026	1.052MetAsn: 1.052 ± 0.027	1.287MetPro: 1.287 ± 0.032	1.008MetGln: 1.008 ± 0.03	1.381MetArg: 1.381 ± 0.031	1.952MetSer: 1.952 ± 0.039	1.833MetThr: 1.833 ± 0.047	1.719MetVal: 1.719 ± 0.042	0.192MetTrp: 0.192 ± 0.012	0.463MetTyr: 0.463 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.586AsnAla: 3.586 ± 0.131	0.305AsnCys: 0.305 ± 0.017	2.616AsnAsp: 2.616 ± 0.149	2.387AsnGlu: 2.387 ± 0.046	1.368AsnPhe: 1.368 ± 0.039	3.004AsnGly: 3.004 ± 0.077	0.754AsnHis: 0.754 ± 0.025	2.221AsnIle: 2.221 ± 0.04	1.474AsnLys: 1.474 ± 0.041	3.43AsnLeu: 3.43 ± 0.058	0.89AsnMet: 0.89 ± 0.025	1.516AsnAsn: 1.516 ± 0.071	2.104AsnPro: 2.104 ± 0.047	1.44AsnGln: 1.44 ± 0.031	1.981AsnArg: 1.981 ± 0.043	2.379AsnSer: 2.379 ± 0.052	2.136AsnThr: 2.136 ± 0.048	2.264AsnVal: 2.264 ± 0.055	0.475AsnTrp: 0.475 ± 0.02	1.19AsnTyr: 1.19 ± 0.039	0.0AsnXaa: 0.0 ± 0.0
Pro	4.217ProAla: 4.217 ± 0.072	0.32ProCys: 0.32 ± 0.018	3.59ProAsp: 3.59 ± 0.086	4.171ProGlu: 4.171 ± 0.072	1.543ProPhe: 1.543 ± 0.036	3.313ProGly: 3.313 ± 0.057	0.844ProHis: 0.844 ± 0.032	1.774ProIle: 1.774 ± 0.036	1.472ProLys: 1.472 ± 0.04	4.202ProLeu: 4.202 ± 0.065	1.048ProMet: 1.048 ± 0.031	1.253ProAsn: 1.253 ± 0.042	1.404ProPro: 1.404 ± 0.043	1.544ProGln: 1.544 ± 0.044	1.667ProArg: 1.667 ± 0.046	2.389ProSer: 2.389 ± 0.043	2.031ProThr: 2.031 ± 0.049	3.943ProVal: 3.943 ± 0.069	0.519ProTrp: 0.519 ± 0.023	1.141ProTyr: 1.141 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	4.075GlnAla: 4.075 ± 0.074	0.334GlnCys: 0.334 ± 0.018	1.849GlnAsp: 1.849 ± 0.045	2.331GlnGlu: 2.331 ± 0.052	1.435GlnPhe: 1.435 ± 0.036	2.57GlnGly: 2.57 ± 0.043	0.867GlnHis: 0.867 ± 0.03	2.098GlnIle: 2.098 ± 0.047	1.789GlnLys: 1.789 ± 0.036	4.341GlnLeu: 4.341 ± 0.078	0.96GlnMet: 0.96 ± 0.031	1.283GlnAsn: 1.283 ± 0.031	1.696GlnPro: 1.696 ± 0.043	2.306GlnGln: 2.306 ± 0.055	2.624GlnArg: 2.624 ± 0.057	2.519GlnSer: 2.519 ± 0.056	1.967GlnThr: 1.967 ± 0.046	2.902GlnVal: 2.902 ± 0.052	0.656GlnTrp: 0.656 ± 0.026	1.077GlnTyr: 1.077 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	4.39ArgAla: 4.39 ± 0.072	0.46ArgCys: 0.46 ± 0.02	3.304ArgAsp: 3.304 ± 0.07	3.891ArgGlu: 3.891 ± 0.062	2.466ArgPhe: 2.466 ± 0.048	3.151ArgGly: 3.151 ± 0.06	1.358ArgHis: 1.358 ± 0.038	3.552ArgIle: 3.552 ± 0.06	2.395ArgLys: 2.395 ± 0.05	6.156ArgLeu: 6.156 ± 0.092	1.516ArgMet: 1.516 ± 0.035	2.038ArgAsn: 2.038 ± 0.042	2.093ArgPro: 2.093 ± 0.04	2.526ArgGln: 2.526 ± 0.056	3.418ArgArg: 3.418 ± 0.067	3.396ArgSer: 3.396 ± 0.056	2.665ArgThr: 2.665 ± 0.047	3.707ArgVal: 3.707 ± 0.069	0.918ArgTrp: 0.918 ± 0.027	1.975ArgTyr: 1.975 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.508SerAla: 6.508 ± 0.094	0.551SerCys: 0.551 ± 0.023	4.866SerAsp: 4.866 ± 0.113	4.687SerGlu: 4.687 ± 0.068	2.542SerPhe: 2.542 ± 0.054	5.967SerGly: 5.967 ± 0.093	1.319SerHis: 1.319 ± 0.032	3.463SerIle: 3.463 ± 0.061	2.335SerLys: 2.335 ± 0.05	6.899SerLeu: 6.899 ± 0.073	1.649SerMet: 1.649 ± 0.037	2.222SerAsn: 2.222 ± 0.045	2.687SerPro: 2.687 ± 0.051	2.58SerGln: 2.58 ± 0.051	3.465SerArg: 3.465 ± 0.063	4.438SerSer: 4.438 ± 0.069	3.301SerThr: 3.301 ± 0.057	5.056SerVal: 5.056 ± 0.079	0.844SerTrp: 0.844 ± 0.026	1.906SerTyr: 1.906 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	5.146ThrAla: 5.146 ± 0.094	0.493ThrCys: 0.493 ± 0.02	3.933ThrAsp: 3.933 ± 0.155	3.686ThrGlu: 3.686 ± 0.058	1.987ThrPhe: 1.987 ± 0.058	4.914ThrGly: 4.914 ± 0.118	1.031ThrHis: 1.031 ± 0.03	2.793ThrIle: 2.793 ± 0.053	1.547ThrLys: 1.547 ± 0.038	6.481ThrLeu: 6.481 ± 0.097	1.114ThrMet: 1.114 ± 0.036	1.795ThrAsn: 1.795 ± 0.065	2.987ThrPro: 2.987 ± 0.057	2.052ThrGln: 2.052 ± 0.048	2.707ThrArg: 2.707 ± 0.055	3.515ThrSer: 3.515 ± 0.068	3.069ThrThr: 3.069 ± 0.057	3.947ThrVal: 3.947 ± 0.082	0.593ThrTrp: 0.593 ± 0.026	1.556ThrTyr: 1.556 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	6.856ValAla: 6.856 ± 0.091	0.688ValCys: 0.688 ± 0.025	4.311ValAsp: 4.311 ± 0.08	4.53ValGlu: 4.53 ± 0.075	2.563ValPhe: 2.563 ± 0.049	4.436ValGly: 4.436 ± 0.071	1.297ValHis: 1.297 ± 0.037	4.297ValIle: 4.297 ± 0.06	2.793ValLys: 2.793 ± 0.059	6.822ValLeu: 6.822 ± 0.087	1.925ValMet: 1.925 ± 0.044	2.819ValAsn: 2.819 ± 0.074	2.918ValPro: 2.918 ± 0.055	2.256ValGln: 2.256 ± 0.044	3.8ValArg: 3.8 ± 0.065	5.315ValSer: 5.315 ± 0.097	4.594ValThr: 4.594 ± 0.1	5.382ValVal: 5.382 ± 0.084	0.79ValTrp: 0.79 ± 0.027	1.815ValTyr: 1.815 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.96TrpAla: 0.96 ± 0.029	0.137TrpCys: 0.137 ± 0.011	0.67TrpAsp: 0.67 ± 0.022	0.651TrpGlu: 0.651 ± 0.024	0.559TrpPhe: 0.559 ± 0.022	0.781TrpGly: 0.781 ± 0.03	0.368TrpHis: 0.368 ± 0.019	0.653TrpIle: 0.653 ± 0.025	0.487TrpLys: 0.487 ± 0.021	1.833TrpLeu: 1.833 ± 0.045	0.407TrpMet: 0.407 ± 0.018	0.517TrpAsn: 0.517 ± 0.024	0.545TrpPro: 0.545 ± 0.02	0.786TrpGln: 0.786 ± 0.031	0.807TrpArg: 0.807 ± 0.028	0.793TrpSer: 0.793 ± 0.031	0.57TrpThr: 0.57 ± 0.025	0.918TrpVal: 0.918 ± 0.029	0.203TrpTrp: 0.203 ± 0.013	0.371TrpTyr: 0.371 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.274TyrAla: 2.274 ± 0.047	0.318TyrCys: 0.318 ± 0.017	1.811TyrAsp: 1.811 ± 0.047	1.856TyrGlu: 1.856 ± 0.041	1.251TyrPhe: 1.251 ± 0.037	2.058TyrGly: 2.058 ± 0.045	0.613TyrHis: 0.613 ± 0.024	1.456TyrIle: 1.456 ± 0.042	0.973TyrLys: 0.973 ± 0.028	3.066TyrLeu: 3.066 ± 0.057	0.587TyrMet: 0.587 ± 0.024	0.985TyrAsn: 0.985 ± 0.032	1.351TyrPro: 1.351 ± 0.038	1.46TyrGln: 1.46 ± 0.044	1.972TyrArg: 1.972 ± 0.048	2.017TyrSer: 2.017 ± 0.04	1.497TyrThr: 1.497 ± 0.038	1.733TyrVal: 1.733 ± 0.041	0.412TyrTrp: 0.412 ± 0.021	0.938TyrTyr: 0.938 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3470 proteins (1171308 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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