Amino acid dipepetide frequency for Hubei tombus-like virus 25

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.63AlaAla: 10.63 ± 3.38
0.759AlaCys: 0.759 ± 0.489
3.037AlaAsp: 3.037 ± 0.601
6.074AlaGlu: 6.074 ± 1.43
8.352AlaPhe: 8.352 ± 0.859
7.593AlaGly: 7.593 ± 1.895
0.0AlaHis: 0.0 ± 0.0
4.556AlaIle: 4.556 ± 1.468
3.797AlaLys: 3.797 ± 1.091
3.797AlaLeu: 3.797 ± 1.183
2.278AlaMet: 2.278 ± 1.427
7.593AlaAsn: 7.593 ± 1.127
3.797AlaPro: 3.797 ± 1.183
0.759AlaGln: 0.759 ± 0.489
5.315AlaArg: 5.315 ± 1.595
4.556AlaSer: 4.556 ± 2.515
3.037AlaThr: 3.037 ± 0.601
9.112AlaVal: 9.112 ± 3.555
1.519AlaTrp: 1.519 ± 0.414
2.278AlaTyr: 2.278 ± 0.734
0.0AlaXaa: 0.0 ± 0.0
Cys
1.519CysAla: 1.519 ± 0.675
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.519CysGlu: 1.519 ± 0.675
0.0CysPhe: 0.0 ± 0.0
0.759CysGly: 0.759 ± 0.755
0.0CysHis: 0.0 ± 0.0
1.519CysIle: 1.519 ± 0.675
1.519CysLys: 1.519 ± 0.675
1.519CysLeu: 1.519 ± 0.978
0.0CysMet: 0.0 ± 0.0
0.759CysAsn: 0.759 ± 0.489
0.759CysPro: 0.759 ± 0.532
0.759CysGln: 0.759 ± 0.489
0.759CysArg: 0.759 ± 0.489
2.278CysSer: 2.278 ± 1.467
0.759CysThr: 0.759 ± 0.489
0.759CysVal: 0.759 ± 0.489
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.834AspAla: 6.834 ± 3.987
0.0AspCys: 0.0 ± 0.0
3.037AspAsp: 3.037 ± 0.601
4.556AspGlu: 4.556 ± 2.025
3.037AspPhe: 3.037 ± 1.104
2.278AspGly: 2.278 ± 1.467
1.519AspHis: 1.519 ± 0.978
2.278AspIle: 2.278 ± 0.354
2.278AspLys: 2.278 ± 1.467
6.834AspLeu: 6.834 ± 0.217
0.0AspMet: 0.0 ± 0.0
0.759AspAsn: 0.759 ± 0.755
3.037AspPro: 3.037 ± 1.525
0.0AspGln: 0.0 ± 0.0
3.037AspArg: 3.037 ± 1.956
5.315AspSer: 5.315 ± 1.595
3.037AspThr: 3.037 ± 0.601
4.556AspVal: 4.556 ± 1.778
1.519AspTrp: 1.519 ± 0.414
1.519AspTyr: 1.519 ± 0.768
0.0AspXaa: 0.0 ± 0.0
Glu
3.797GluAla: 3.797 ± 2.817
0.759GluCys: 0.759 ± 0.489
3.797GluAsp: 3.797 ± 1.52
0.0GluGlu: 0.0 ± 0.0
1.519GluPhe: 1.519 ± 0.675
1.519GluGly: 1.519 ± 0.675
0.0GluHis: 0.0 ± 0.0
1.519GluIle: 1.519 ± 0.978
3.797GluLys: 3.797 ± 1.645
4.556GluLeu: 4.556 ± 1.266
2.278GluMet: 2.278 ± 0.905
3.037GluAsn: 3.037 ± 0.374
3.037GluPro: 3.037 ± 0.601
3.037GluGln: 3.037 ± 1.956
0.759GluArg: 0.759 ± 0.489
3.037GluSer: 3.037 ± 0.828
4.556GluThr: 4.556 ± 1.01
2.278GluVal: 2.278 ± 2.264
0.759GluTrp: 0.759 ± 0.489
2.278GluTyr: 2.278 ± 0.818
0.0GluXaa: 0.0 ± 0.0
Phe
2.278PheAla: 2.278 ± 1.595
1.519PheCys: 1.519 ± 0.978
3.037PheAsp: 3.037 ± 1.35
3.797PheGlu: 3.797 ± 1.727
1.519PhePhe: 1.519 ± 1.063
3.797PheGly: 3.797 ± 0.158
0.0PheHis: 0.0 ± 0.0
1.519PheIle: 1.519 ± 0.414
1.519PheLys: 1.519 ± 0.978
3.037PheLeu: 3.037 ± 0.601
0.759PheMet: 0.759 ± 0.755
0.759PheAsn: 0.759 ± 0.532
2.278PhePro: 2.278 ± 1.595
2.278PheGln: 2.278 ± 0.818
3.797PheArg: 3.797 ± 1.857
3.037PheSer: 3.037 ± 1.956
2.278PheThr: 2.278 ± 0.818
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.315GlyAla: 5.315 ± 1.595
1.519GlyCys: 1.519 ± 1.509
2.278GlyAsp: 2.278 ± 0.734
3.037GlyGlu: 3.037 ± 0.828
0.759GlyPhe: 0.759 ± 0.532
4.556GlyGly: 4.556 ± 0.69
2.278GlyHis: 2.278 ± 0.905
5.315GlyIle: 5.315 ± 1.683
6.074GlyLys: 6.074 ± 2.41
3.797GlyLeu: 3.797 ± 0.795
0.759GlyMet: 0.759 ± 0.532
3.037GlyAsn: 3.037 ± 0.601
1.519GlyPro: 1.519 ± 0.768
1.519GlyGln: 1.519 ± 0.675
2.278GlyArg: 2.278 ± 0.905
5.315GlySer: 5.315 ± 1.221
6.834GlyThr: 6.834 ± 2.595
7.593GlyVal: 7.593 ± 0.316
1.519GlyTrp: 1.519 ± 1.063
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.759HisPhe: 0.759 ± 0.532
0.759HisGly: 0.759 ± 0.489
0.0HisHis: 0.0 ± 0.0
0.759HisIle: 0.759 ± 0.489
2.278HisLys: 2.278 ± 0.818
1.519HisLeu: 1.519 ± 0.978
1.519HisMet: 1.519 ± 0.746
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.759HisGln: 0.759 ± 0.755
2.278HisArg: 2.278 ± 0.734
0.0HisSer: 0.0 ± 0.0
0.759HisThr: 0.759 ± 0.755
0.759HisVal: 0.759 ± 0.489
0.0HisTrp: 0.0 ± 0.0
1.519HisTyr: 1.519 ± 0.978
0.0HisXaa: 0.0 ± 0.0
Ile
4.556IleAla: 4.556 ± 1.266
0.759IleCys: 0.759 ± 0.532
5.315IleAsp: 5.315 ± 0.54
3.037IleGlu: 3.037 ± 2.075
3.037IlePhe: 3.037 ± 0.374
3.797IleGly: 3.797 ± 1.087
0.759IleHis: 0.759 ± 0.532
3.037IleIle: 3.037 ± 1.289
3.797IleLys: 3.797 ± 0.795
6.834IleLeu: 6.834 ± 0.924
0.759IleMet: 0.759 ± 0.532
3.037IleAsn: 3.037 ± 0.374
4.556IlePro: 4.556 ± 1.636
2.278IleGln: 2.278 ± 0.818
1.519IleArg: 1.519 ± 0.414
4.556IleSer: 4.556 ± 2.934
3.797IleThr: 3.797 ± 1.078
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
0.759IleTyr: 0.759 ± 0.532
0.0IleXaa: 0.0 ± 0.0
Lys
6.834LysAla: 6.834 ± 1.134
0.759LysCys: 0.759 ± 0.755
0.0LysAsp: 0.0 ± 0.0
3.037LysGlu: 3.037 ± 1.104
1.519LysPhe: 1.519 ± 0.414
2.278LysGly: 2.278 ± 1.595
0.759LysHis: 0.759 ± 0.489
3.037LysIle: 3.037 ± 1.35
4.556LysLys: 4.556 ± 1.636
2.278LysLeu: 2.278 ± 0.354
1.519LysMet: 1.519 ± 0.675
5.315LysAsn: 5.315 ± 0.54
1.519LysPro: 1.519 ± 0.675
1.519LysGln: 1.519 ± 1.063
7.593LysArg: 7.593 ± 1.365
4.556LysSer: 4.556 ± 0.409
4.556LysThr: 4.556 ± 1.243
4.556LysVal: 4.556 ± 0.409
0.759LysTrp: 0.759 ± 0.532
2.278LysTyr: 2.278 ± 0.905
0.0LysXaa: 0.0 ± 0.0
Leu
6.834LeuAla: 6.834 ± 2.454
0.759LeuCys: 0.759 ± 0.489
6.834LeuAsp: 6.834 ± 2.716
3.797LeuGlu: 3.797 ± 0.158
3.037LeuPhe: 3.037 ± 1.176
4.556LeuGly: 4.556 ± 1.661
3.037LeuHis: 3.037 ± 0.601
5.315LeuIle: 5.315 ± 1.472
3.797LeuLys: 3.797 ± 1.091
9.112LeuLeu: 9.112 ± 1.866
4.556LeuMet: 4.556 ± 0.409
5.315LeuAsn: 5.315 ± 1.221
3.037LeuPro: 3.037 ± 1.35
1.519LeuGln: 1.519 ± 0.978
3.037LeuArg: 3.037 ± 1.176
6.834LeuSer: 6.834 ± 2.454
4.556LeuThr: 4.556 ± 0.409
2.278LeuVal: 2.278 ± 1.346
1.519LeuTrp: 1.519 ± 0.978
1.519LeuTyr: 1.519 ± 1.063
0.0LeuXaa: 0.0 ± 0.0
Met
5.315MetAla: 5.315 ± 1.221
0.0MetCys: 0.0 ± 0.0
3.037MetAsp: 3.037 ± 1.536
2.278MetGlu: 2.278 ± 1.467
0.759MetPhe: 0.759 ± 0.755
1.519MetGly: 1.519 ± 0.768
0.0MetHis: 0.0 ± 0.0
1.519MetIle: 1.519 ± 1.063
1.519MetLys: 1.519 ± 1.509
1.519MetLeu: 1.519 ± 0.768
2.278MetMet: 2.278 ± 1.346
2.278MetAsn: 2.278 ± 0.354
1.519MetPro: 1.519 ± 0.414
0.759MetGln: 0.759 ± 0.489
3.037MetArg: 3.037 ± 0.828
1.519MetSer: 1.519 ± 0.978
1.519MetThr: 1.519 ± 1.509
2.278MetVal: 2.278 ± 1.346
0.0MetTrp: 0.0 ± 0.0
0.759MetTyr: 0.759 ± 0.489
0.0MetXaa: 0.0 ± 0.0
Asn
4.556AsnAla: 4.556 ± 1.778
1.519AsnCys: 1.519 ± 0.675
3.797AsnAsp: 3.797 ± 0.938
0.759AsnGlu: 0.759 ± 0.489
1.519AsnPhe: 1.519 ± 0.414
4.556AsnGly: 4.556 ± 0.409
0.0AsnHis: 0.0 ± 0.0
0.759AsnIle: 0.759 ± 0.532
4.556AsnLys: 4.556 ± 0.69
5.315AsnLeu: 5.315 ± 0.54
1.519AsnMet: 1.519 ± 1.063
3.037AsnAsn: 3.037 ± 2.126
3.037AsnPro: 3.037 ± 2.126
1.519AsnGln: 1.519 ± 0.978
2.278AsnArg: 2.278 ± 0.818
2.278AsnSer: 2.278 ± 0.354
3.797AsnThr: 3.797 ± 1.183
3.797AsnVal: 3.797 ± 1.078
2.278AsnTrp: 2.278 ± 1.467
3.797AsnTyr: 3.797 ± 1.091
0.0AsnXaa: 0.0 ± 0.0
Pro
4.556ProAla: 4.556 ± 1.59
0.0ProCys: 0.0 ± 0.0
0.759ProAsp: 0.759 ± 0.532
0.759ProGlu: 0.759 ± 0.489
0.0ProPhe: 0.0 ± 0.0
3.797ProGly: 3.797 ± 1.091
0.0ProHis: 0.0 ± 0.0
3.037ProIle: 3.037 ± 1.176
0.759ProLys: 0.759 ± 0.755
6.834ProLeu: 6.834 ± 2.454
1.519ProMet: 1.519 ± 0.978
2.278ProAsn: 2.278 ± 0.354
0.759ProPro: 0.759 ± 0.532
3.037ProGln: 3.037 ± 2.126
3.037ProArg: 3.037 ± 1.35
3.037ProSer: 3.037 ± 0.601
3.797ProThr: 3.797 ± 2.658
6.074ProVal: 6.074 ± 0.733
1.519ProTrp: 1.519 ± 1.063
1.519ProTyr: 1.519 ± 0.978
0.0ProXaa: 0.0 ± 0.0
Gln
2.278GlnAla: 2.278 ± 0.905
0.759GlnCys: 0.759 ± 0.489
0.759GlnAsp: 0.759 ± 0.532
0.759GlnGlu: 0.759 ± 0.489
0.759GlnPhe: 0.759 ± 0.489
3.797GlnGly: 3.797 ± 0.158
0.759GlnHis: 0.759 ± 0.489
3.797GlnIle: 3.797 ± 1.645
2.278GlnLys: 2.278 ± 0.354
3.037GlnLeu: 3.037 ± 0.828
3.037GlnMet: 3.037 ± 1.536
0.759GlnAsn: 0.759 ± 0.532
2.278GlnPro: 2.278 ± 0.734
2.278GlnGln: 2.278 ± 0.734
2.278GlnArg: 2.278 ± 1.084
1.519GlnSer: 1.519 ± 0.414
1.519GlnThr: 1.519 ± 0.414
0.759GlnVal: 0.759 ± 0.532
0.0GlnTrp: 0.0 ± 0.0
0.759GlnTyr: 0.759 ± 0.489
0.0GlnXaa: 0.0 ± 0.0
Arg
6.074ArgAla: 6.074 ± 1.43
3.037ArgCys: 3.037 ± 1.956
2.278ArgAsp: 2.278 ± 1.346
2.278ArgGlu: 2.278 ± 1.467
1.519ArgPhe: 1.519 ± 0.414
2.278ArgGly: 2.278 ± 0.734
0.759ArgHis: 0.759 ± 0.489
4.556ArgIle: 4.556 ± 1.01
0.759ArgLys: 0.759 ± 0.755
3.037ArgLeu: 3.037 ± 1.289
1.519ArgMet: 1.519 ± 0.768
5.315ArgAsn: 5.315 ± 0.887
3.797ArgPro: 3.797 ± 0.795
1.519ArgGln: 1.519 ± 0.675
4.556ArgArg: 4.556 ± 1.01
4.556ArgSer: 4.556 ± 0.69
3.037ArgThr: 3.037 ± 0.828
1.519ArgVal: 1.519 ± 1.509
0.759ArgTrp: 0.759 ± 0.489
5.315ArgTyr: 5.315 ± 1.899
0.0ArgXaa: 0.0 ± 0.0
Ser
6.834SerAla: 6.834 ± 1.471
0.0SerCys: 0.0 ± 0.0
2.278SerAsp: 2.278 ± 0.354
1.519SerGlu: 1.519 ± 0.675
4.556SerPhe: 4.556 ± 1.243
7.593SerGly: 7.593 ± 1.127
1.519SerHis: 1.519 ± 0.978
4.556SerIle: 4.556 ± 0.709
3.037SerLys: 3.037 ± 2.126
4.556SerLeu: 4.556 ± 0.409
2.278SerMet: 2.278 ± 0.734
2.278SerAsn: 2.278 ± 0.818
3.037SerPro: 3.037 ± 1.176
3.037SerGln: 3.037 ± 1.316
3.797SerArg: 3.797 ± 1.645
1.519SerSer: 1.519 ± 0.414
6.074SerThr: 6.074 ± 1.991
4.556SerVal: 4.556 ± 1.01
1.519SerTrp: 1.519 ± 0.414
5.315SerTyr: 5.315 ± 0.887
0.0SerXaa: 0.0 ± 0.0
Thr
3.037ThrAla: 3.037 ± 1.316
0.759ThrCys: 0.759 ± 0.489
4.556ThrAsp: 4.556 ± 1.59
2.278ThrGlu: 2.278 ± 0.905
1.519ThrPhe: 1.519 ± 1.063
3.037ThrGly: 3.037 ± 0.601
0.759ThrHis: 0.759 ± 0.532
6.074ThrIle: 6.074 ± 1.991
5.315ThrLys: 5.315 ± 1.221
4.556ThrLeu: 4.556 ± 1.661
0.759ThrMet: 0.759 ± 0.532
1.519ThrAsn: 1.519 ± 0.414
4.556ThrPro: 4.556 ± 2.515
3.037ThrGln: 3.037 ± 0.374
3.037ThrArg: 3.037 ± 1.35
6.834ThrSer: 6.834 ± 1.471
6.074ThrThr: 6.074 ± 1.657
5.315ThrVal: 5.315 ± 2.126
0.0ThrTrp: 0.0 ± 0.0
6.074ThrTyr: 6.074 ± 0.733
0.0ThrXaa: 0.0 ± 0.0
Val
3.797ValAla: 3.797 ± 1.802
1.519ValCys: 1.519 ± 0.675
6.074ValAsp: 6.074 ± 3.33
2.278ValGlu: 2.278 ± 1.467
1.519ValPhe: 1.519 ± 0.414
6.074ValGly: 6.074 ± 1.247
0.759ValHis: 0.759 ± 0.755
0.0ValIle: 0.0 ± 0.0
5.315ValLys: 5.315 ± 0.517
3.037ValLeu: 3.037 ± 0.374
3.037ValMet: 3.037 ± 1.853
3.797ValAsn: 3.797 ± 1.078
3.797ValPro: 3.797 ± 0.795
2.278ValGln: 2.278 ± 1.427
2.278ValArg: 2.278 ± 0.818
6.834ValSer: 6.834 ± 0.73
5.315ValThr: 5.315 ± 2.111
1.519ValVal: 1.519 ± 1.509
0.0ValTrp: 0.0 ± 0.0
2.278ValTyr: 2.278 ± 0.905
0.0ValXaa: 0.0 ± 0.0
Trp
1.519TrpAla: 1.519 ± 1.063
0.0TrpCys: 0.0 ± 0.0
1.519TrpAsp: 1.519 ± 0.978
0.759TrpGlu: 0.759 ± 0.489
0.0TrpPhe: 0.0 ± 0.0
0.759TrpGly: 0.759 ± 0.532
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.519TrpLys: 1.519 ± 0.978
3.037TrpLeu: 3.037 ± 0.828
0.759TrpMet: 0.759 ± 0.402
2.278TrpAsn: 2.278 ± 0.818
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.759TrpArg: 0.759 ± 0.489
0.759TrpSer: 0.759 ± 0.489
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.278TyrAla: 2.278 ± 1.467
0.759TyrCys: 0.759 ± 0.489
3.037TyrAsp: 3.037 ± 0.601
3.797TyrGlu: 3.797 ± 0.158
1.519TyrPhe: 1.519 ± 0.675
0.0TyrGly: 0.0 ± 0.0
0.759TyrHis: 0.759 ± 0.489
3.037TyrIle: 3.037 ± 0.601
0.759TyrLys: 0.759 ± 0.489
3.037TyrLeu: 3.037 ± 0.601
1.519TyrMet: 1.519 ± 0.978
1.519TyrAsn: 1.519 ± 0.414
0.759TyrPro: 0.759 ± 0.489
2.278TyrGln: 2.278 ± 0.734
3.037TyrArg: 3.037 ± 0.374
1.519TyrSer: 1.519 ± 1.063
3.797TyrThr: 3.797 ± 0.795
3.797TyrVal: 3.797 ± 1.087
0.759TyrTrp: 0.759 ± 0.489
1.519TyrTyr: 1.519 ± 0.675
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1318 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski