Amino acid dipepetide frequency for Alteromonas virus vB_AspP-H4/4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.292AlaAla: 8.292 ± 1.008
0.583AlaCys: 0.583 ± 0.174
3.952AlaAsp: 3.952 ± 0.566
6.348AlaGlu: 6.348 ± 0.793
3.239AlaPhe: 3.239 ± 0.337
6.024AlaGly: 6.024 ± 0.82
1.101AlaHis: 1.101 ± 0.274
4.146AlaIle: 4.146 ± 0.569
6.413AlaLys: 6.413 ± 0.917
7.968AlaLeu: 7.968 ± 0.674
2.073AlaMet: 2.073 ± 0.422
4.729AlaAsn: 4.729 ± 0.549
1.684AlaPro: 1.684 ± 0.291
4.016AlaGln: 4.016 ± 0.62
3.498AlaArg: 3.498 ± 0.486
4.34AlaSer: 4.34 ± 0.531
4.858AlaThr: 4.858 ± 0.588
4.535AlaVal: 4.535 ± 0.526
0.907AlaTrp: 0.907 ± 0.262
3.433AlaTyr: 3.433 ± 0.468
0.0AlaXaa: 0.0 ± 0.0
Cys
0.777CysAla: 0.777 ± 0.227
0.0CysCys: 0.0 ± 0.0
0.324CysAsp: 0.324 ± 0.133
0.389CysGlu: 0.389 ± 0.199
0.194CysPhe: 0.194 ± 0.115
0.259CysGly: 0.259 ± 0.169
0.324CysHis: 0.324 ± 0.143
0.648CysIle: 0.648 ± 0.215
0.972CysLys: 0.972 ± 0.255
0.453CysLeu: 0.453 ± 0.166
0.389CysMet: 0.389 ± 0.182
0.583CysAsn: 0.583 ± 0.228
0.13CysPro: 0.13 ± 0.089
0.324CysGln: 0.324 ± 0.132
0.324CysArg: 0.324 ± 0.131
0.194CysSer: 0.194 ± 0.124
0.518CysThr: 0.518 ± 0.158
1.036CysVal: 1.036 ± 0.23
0.0CysTrp: 0.0 ± 0.0
0.518CysTyr: 0.518 ± 0.224
0.0CysXaa: 0.0 ± 0.0
Asp
4.47AspAla: 4.47 ± 0.605
0.777AspCys: 0.777 ± 0.233
4.794AspAsp: 4.794 ± 0.524
4.146AspGlu: 4.146 ± 0.632
2.915AspPhe: 2.915 ± 0.414
5.182AspGly: 5.182 ± 0.606
0.842AspHis: 0.842 ± 0.226
5.053AspIle: 5.053 ± 0.727
5.247AspLys: 5.247 ± 0.655
5.053AspLeu: 5.053 ± 0.422
1.943AspMet: 1.943 ± 0.301
2.915AspAsn: 2.915 ± 0.551
2.591AspPro: 2.591 ± 0.366
1.749AspGln: 1.749 ± 0.401
2.786AspArg: 2.786 ± 0.386
3.692AspSer: 3.692 ± 0.464
4.275AspThr: 4.275 ± 0.567
5.895AspVal: 5.895 ± 0.483
0.972AspTrp: 0.972 ± 0.392
2.98AspTyr: 2.98 ± 0.314
0.0AspXaa: 0.0 ± 0.0
Glu
6.219GluAla: 6.219 ± 0.799
0.777GluCys: 0.777 ± 0.221
5.312GluAsp: 5.312 ± 0.494
6.219GluGlu: 6.219 ± 0.581
2.786GluPhe: 2.786 ± 0.385
3.692GluGly: 3.692 ± 0.526
1.619GluHis: 1.619 ± 0.285
4.211GluIle: 4.211 ± 0.507
3.369GluLys: 3.369 ± 0.388
7.644GluLeu: 7.644 ± 0.721
1.555GluMet: 1.555 ± 0.282
3.433GluAsn: 3.433 ± 0.486
2.138GluPro: 2.138 ± 0.376
3.369GluGln: 3.369 ± 0.566
3.628GluArg: 3.628 ± 0.408
4.211GluSer: 4.211 ± 0.497
3.822GluThr: 3.822 ± 0.416
5.96GluVal: 5.96 ± 0.628
1.296GluTrp: 1.296 ± 0.301
2.98GluTyr: 2.98 ± 0.404
0.0GluXaa: 0.0 ± 0.0
Phe
2.526PheAla: 2.526 ± 0.45
0.13PheCys: 0.13 ± 0.087
2.85PheAsp: 2.85 ± 0.467
2.591PheGlu: 2.591 ± 0.331
1.619PhePhe: 1.619 ± 0.331
2.656PheGly: 2.656 ± 0.422
0.713PheHis: 0.713 ± 0.169
2.203PheIle: 2.203 ± 0.448
2.267PheLys: 2.267 ± 0.372
2.397PheLeu: 2.397 ± 0.439
0.713PheMet: 0.713 ± 0.248
2.397PheAsn: 2.397 ± 0.311
1.879PhePro: 1.879 ± 0.314
1.36PheGln: 1.36 ± 0.277
1.749PheArg: 1.749 ± 0.27
1.943PheSer: 1.943 ± 0.313
2.332PheThr: 2.332 ± 0.415
1.749PheVal: 1.749 ± 0.345
0.389PheTrp: 0.389 ± 0.132
1.036PheTyr: 1.036 ± 0.286
0.0PheXaa: 0.0 ± 0.0
Gly
4.664GlyAla: 4.664 ± 0.526
0.453GlyCys: 0.453 ± 0.151
5.247GlyAsp: 5.247 ± 0.593
4.47GlyGlu: 4.47 ± 0.473
2.267GlyPhe: 2.267 ± 0.443
4.535GlyGly: 4.535 ± 0.69
1.036GlyHis: 1.036 ± 0.25
3.239GlyIle: 3.239 ± 0.373
5.377GlyLys: 5.377 ± 0.667
4.858GlyLeu: 4.858 ± 0.483
2.397GlyMet: 2.397 ± 0.294
3.692GlyAsn: 3.692 ± 0.587
0.065GlyPro: 0.065 ± 0.053
2.526GlyGln: 2.526 ± 0.497
4.016GlyArg: 4.016 ± 0.516
3.628GlySer: 3.628 ± 0.426
4.47GlyThr: 4.47 ± 0.799
5.96GlyVal: 5.96 ± 0.514
1.231GlyTrp: 1.231 ± 0.268
3.433GlyTyr: 3.433 ± 0.338
0.0GlyXaa: 0.0 ± 0.0
His
0.907HisAla: 0.907 ± 0.2
0.259HisCys: 0.259 ± 0.112
1.555HisAsp: 1.555 ± 0.273
1.296HisGlu: 1.296 ± 0.318
0.583HisPhe: 0.583 ± 0.204
1.555HisGly: 1.555 ± 0.334
0.324HisHis: 0.324 ± 0.199
0.518HisIle: 0.518 ± 0.167
1.749HisLys: 1.749 ± 0.424
1.101HisLeu: 1.101 ± 0.297
0.907HisMet: 0.907 ± 0.267
0.907HisAsn: 0.907 ± 0.217
0.907HisPro: 0.907 ± 0.202
0.907HisGln: 0.907 ± 0.27
0.648HisArg: 0.648 ± 0.183
1.296HisSer: 1.296 ± 0.282
1.296HisThr: 1.296 ± 0.243
1.101HisVal: 1.101 ± 0.248
0.453HisTrp: 0.453 ± 0.158
0.583HisTyr: 0.583 ± 0.17
0.0HisXaa: 0.0 ± 0.0
Ile
4.275IleAla: 4.275 ± 0.686
0.518IleCys: 0.518 ± 0.177
4.535IleAsp: 4.535 ± 0.475
3.952IleGlu: 3.952 ± 0.464
1.36IlePhe: 1.36 ± 0.249
3.822IleGly: 3.822 ± 0.431
1.425IleHis: 1.425 ± 0.286
3.304IleIle: 3.304 ± 0.608
3.692IleLys: 3.692 ± 0.518
2.98IleLeu: 2.98 ± 0.529
1.619IleMet: 1.619 ± 0.425
3.304IleAsn: 3.304 ± 0.484
2.332IlePro: 2.332 ± 0.443
1.879IleGln: 1.879 ± 0.391
3.109IleArg: 3.109 ± 0.509
2.462IleSer: 2.462 ± 0.381
3.563IleThr: 3.563 ± 0.535
3.498IleVal: 3.498 ± 0.468
0.648IleTrp: 0.648 ± 0.214
1.166IleTyr: 1.166 ± 0.313
0.0IleXaa: 0.0 ± 0.0
Lys
6.348LysAla: 6.348 ± 0.756
0.713LysCys: 0.713 ± 0.24
4.34LysAsp: 4.34 ± 0.63
5.765LysGlu: 5.765 ± 0.595
2.332LysPhe: 2.332 ± 0.267
4.146LysGly: 4.146 ± 0.603
1.814LysHis: 1.814 ± 0.433
2.332LysIle: 2.332 ± 0.41
3.174LysLys: 3.174 ± 0.66
5.701LysLeu: 5.701 ± 0.522
1.166LysMet: 1.166 ± 0.262
2.786LysAsn: 2.786 ± 0.475
2.267LysPro: 2.267 ± 0.492
2.98LysGln: 2.98 ± 0.559
3.822LysArg: 3.822 ± 0.667
3.887LysSer: 3.887 ± 0.524
3.952LysThr: 3.952 ± 0.496
4.664LysVal: 4.664 ± 0.608
0.648LysTrp: 0.648 ± 0.203
2.656LysTyr: 2.656 ± 0.466
0.0LysXaa: 0.0 ± 0.0
Leu
6.737LeuAla: 6.737 ± 0.642
0.713LeuCys: 0.713 ± 0.228
6.024LeuAsp: 6.024 ± 0.647
6.802LeuGlu: 6.802 ± 0.628
1.814LeuPhe: 1.814 ± 0.362
5.765LeuGly: 5.765 ± 0.491
1.49LeuHis: 1.49 ± 0.346
3.887LeuIle: 3.887 ± 0.591
4.405LeuLys: 4.405 ± 0.576
5.312LeuLeu: 5.312 ± 0.691
1.879LeuMet: 1.879 ± 0.382
3.952LeuAsn: 3.952 ± 0.372
3.433LeuPro: 3.433 ± 0.465
3.952LeuGln: 3.952 ± 0.373
4.794LeuArg: 4.794 ± 0.607
5.118LeuSer: 5.118 ± 0.641
4.47LeuThr: 4.47 ± 0.348
4.47LeuVal: 4.47 ± 0.626
1.101LeuTrp: 1.101 ± 0.262
2.267LeuTyr: 2.267 ± 0.354
0.0LeuXaa: 0.0 ± 0.0
Met
1.814MetAla: 1.814 ± 0.335
0.324MetCys: 0.324 ± 0.192
1.749MetAsp: 1.749 ± 0.325
1.684MetGlu: 1.684 ± 0.225
1.425MetPhe: 1.425 ± 0.35
1.425MetGly: 1.425 ± 0.354
0.453MetHis: 0.453 ± 0.149
1.749MetIle: 1.749 ± 0.338
1.749MetLys: 1.749 ± 0.44
2.203MetLeu: 2.203 ± 0.356
0.648MetMet: 0.648 ± 0.174
1.425MetAsn: 1.425 ± 0.282
1.36MetPro: 1.36 ± 0.266
1.36MetGln: 1.36 ± 0.246
1.555MetArg: 1.555 ± 0.295
2.591MetSer: 2.591 ± 0.4
1.749MetThr: 1.749 ± 0.25
1.555MetVal: 1.555 ± 0.293
0.389MetTrp: 0.389 ± 0.173
0.972MetTyr: 0.972 ± 0.261
0.0MetXaa: 0.0 ± 0.0
Asn
4.599AsnAla: 4.599 ± 0.536
0.389AsnCys: 0.389 ± 0.206
2.915AsnAsp: 2.915 ± 0.341
3.369AsnGlu: 3.369 ± 0.486
1.749AsnPhe: 1.749 ± 0.264
4.211AsnGly: 4.211 ± 0.726
0.648AsnHis: 0.648 ± 0.238
3.628AsnIle: 3.628 ± 0.449
3.757AsnLys: 3.757 ± 0.789
3.433AsnLeu: 3.433 ± 0.411
1.49AsnMet: 1.49 ± 0.4
2.267AsnAsn: 2.267 ± 0.322
1.943AsnPro: 1.943 ± 0.227
1.619AsnGln: 1.619 ± 0.35
1.814AsnArg: 1.814 ± 0.327
3.239AsnSer: 3.239 ± 0.497
3.433AsnThr: 3.433 ± 0.527
3.239AsnVal: 3.239 ± 0.417
1.101AsnTrp: 1.101 ± 0.231
1.296AsnTyr: 1.296 ± 0.209
0.0AsnXaa: 0.0 ± 0.0
Pro
2.462ProAla: 2.462 ± 0.4
0.324ProCys: 0.324 ± 0.17
2.526ProAsp: 2.526 ± 0.364
3.563ProGlu: 3.563 ± 0.504
1.231ProPhe: 1.231 ± 0.318
0.259ProGly: 0.259 ± 0.15
0.842ProHis: 0.842 ± 0.242
1.749ProIle: 1.749 ± 0.311
2.332ProLys: 2.332 ± 0.464
2.656ProLeu: 2.656 ± 0.326
0.583ProMet: 0.583 ± 0.172
2.138ProAsn: 2.138 ± 0.358
1.231ProPro: 1.231 ± 0.346
1.231ProGln: 1.231 ± 0.268
1.036ProArg: 1.036 ± 0.289
1.425ProSer: 1.425 ± 0.238
3.174ProThr: 3.174 ± 0.432
3.628ProVal: 3.628 ± 0.54
0.518ProTrp: 0.518 ± 0.167
1.166ProTyr: 1.166 ± 0.266
0.0ProXaa: 0.0 ± 0.0
Gln
3.822GlnAla: 3.822 ± 0.584
0.065GlnCys: 0.065 ± 0.077
2.073GlnAsp: 2.073 ± 0.371
2.721GlnGlu: 2.721 ± 0.421
1.814GlnPhe: 1.814 ± 0.409
3.304GlnGly: 3.304 ± 0.517
0.648GlnHis: 0.648 ± 0.251
2.008GlnIle: 2.008 ± 0.297
1.943GlnLys: 1.943 ± 0.339
4.34GlnLeu: 4.34 ± 0.69
1.296GlnMet: 1.296 ± 0.259
1.296GlnAsn: 1.296 ± 0.27
1.425GlnPro: 1.425 ± 0.307
1.879GlnGln: 1.879 ± 0.485
2.591GlnArg: 2.591 ± 0.505
2.721GlnSer: 2.721 ± 0.487
2.397GlnThr: 2.397 ± 0.4
3.045GlnVal: 3.045 ± 0.525
0.583GlnTrp: 0.583 ± 0.203
1.684GlnTyr: 1.684 ± 0.277
0.0GlnXaa: 0.0 ± 0.0
Arg
3.887ArgAla: 3.887 ± 0.522
0.324ArgCys: 0.324 ± 0.141
2.98ArgAsp: 2.98 ± 0.321
3.628ArgGlu: 3.628 ± 0.613
1.619ArgPhe: 1.619 ± 0.377
3.692ArgGly: 3.692 ± 0.39
1.231ArgHis: 1.231 ± 0.315
2.591ArgIle: 2.591 ± 0.31
3.887ArgLys: 3.887 ± 0.57
4.211ArgLeu: 4.211 ± 0.57
2.267ArgMet: 2.267 ± 0.441
2.656ArgAsn: 2.656 ± 0.386
1.749ArgPro: 1.749 ± 0.346
2.85ArgGln: 2.85 ± 0.41
2.85ArgArg: 2.85 ± 0.399
1.814ArgSer: 1.814 ± 0.308
2.786ArgThr: 2.786 ± 0.418
4.34ArgVal: 4.34 ± 0.437
0.13ArgTrp: 0.13 ± 0.111
1.814ArgTyr: 1.814 ± 0.372
0.0ArgXaa: 0.0 ± 0.0
Ser
5.312SerAla: 5.312 ± 0.553
0.842SerCys: 0.842 ± 0.226
3.369SerAsp: 3.369 ± 0.48
3.628SerGlu: 3.628 ± 0.441
2.008SerPhe: 2.008 ± 0.351
4.146SerGly: 4.146 ± 0.658
0.648SerHis: 0.648 ± 0.221
3.239SerIle: 3.239 ± 0.389
4.729SerLys: 4.729 ± 0.79
3.757SerLeu: 3.757 ± 0.515
1.879SerMet: 1.879 ± 0.48
2.786SerAsn: 2.786 ± 0.423
2.332SerPro: 2.332 ± 0.295
2.138SerGln: 2.138 ± 0.342
3.628SerArg: 3.628 ± 0.469
2.915SerSer: 2.915 ± 0.404
4.081SerThr: 4.081 ± 0.55
4.405SerVal: 4.405 ± 0.389
0.777SerTrp: 0.777 ± 0.243
1.036SerTyr: 1.036 ± 0.243
0.0SerXaa: 0.0 ± 0.0
Thr
5.506ThrAla: 5.506 ± 0.698
0.389ThrCys: 0.389 ± 0.199
5.118ThrAsp: 5.118 ± 0.606
4.729ThrGlu: 4.729 ± 0.521
2.332ThrPhe: 2.332 ± 0.367
4.599ThrGly: 4.599 ± 0.646
1.101ThrHis: 1.101 ± 0.239
2.85ThrIle: 2.85 ± 0.664
3.563ThrLys: 3.563 ± 0.463
4.405ThrLeu: 4.405 ± 0.496
1.425ThrMet: 1.425 ± 0.308
2.915ThrAsn: 2.915 ± 0.555
2.786ThrPro: 2.786 ± 0.45
2.915ThrGln: 2.915 ± 0.428
2.85ThrArg: 2.85 ± 0.471
4.081ThrSer: 4.081 ± 0.503
3.692ThrThr: 3.692 ± 0.557
4.34ThrVal: 4.34 ± 0.518
1.036ThrTrp: 1.036 ± 0.25
2.332ThrTyr: 2.332 ± 0.316
0.0ThrXaa: 0.0 ± 0.0
Val
6.478ValAla: 6.478 ± 0.704
0.259ValCys: 0.259 ± 0.143
5.377ValAsp: 5.377 ± 0.508
5.441ValGlu: 5.441 ± 0.567
2.397ValPhe: 2.397 ± 0.363
5.182ValGly: 5.182 ± 0.713
1.296ValHis: 1.296 ± 0.331
2.915ValIle: 2.915 ± 0.404
4.016ValLys: 4.016 ± 0.473
5.182ValLeu: 5.182 ± 0.653
2.462ValMet: 2.462 ± 0.353
3.174ValAsn: 3.174 ± 0.424
2.915ValPro: 2.915 ± 0.438
2.526ValGln: 2.526 ± 0.273
4.081ValArg: 4.081 ± 0.534
4.923ValSer: 4.923 ± 0.691
4.275ValThr: 4.275 ± 0.568
5.441ValVal: 5.441 ± 0.677
1.101ValTrp: 1.101 ± 0.269
2.526ValTyr: 2.526 ± 0.584
0.0ValXaa: 0.0 ± 0.0
Trp
0.842TrpAla: 0.842 ± 0.261
0.13TrpCys: 0.13 ± 0.094
0.972TrpAsp: 0.972 ± 0.179
0.972TrpGlu: 0.972 ± 0.291
0.907TrpPhe: 0.907 ± 0.305
0.453TrpGly: 0.453 ± 0.196
0.389TrpHis: 0.389 ± 0.197
0.972TrpIle: 0.972 ± 0.273
0.907TrpLys: 0.907 ± 0.257
1.814TrpLeu: 1.814 ± 0.323
0.453TrpMet: 0.453 ± 0.179
0.583TrpAsn: 0.583 ± 0.196
0.13TrpPro: 0.13 ± 0.081
0.842TrpGln: 0.842 ± 0.221
0.648TrpArg: 0.648 ± 0.181
0.648TrpSer: 0.648 ± 0.157
0.907TrpThr: 0.907 ± 0.282
0.713TrpVal: 0.713 ± 0.268
0.194TrpTrp: 0.194 ± 0.128
0.389TrpTyr: 0.389 ± 0.148
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.203TyrAla: 2.203 ± 0.332
0.389TyrCys: 0.389 ± 0.16
2.267TyrAsp: 2.267 ± 0.32
2.526TyrGlu: 2.526 ± 0.503
0.907TyrPhe: 0.907 ± 0.259
2.656TyrGly: 2.656 ± 0.425
0.907TyrHis: 0.907 ± 0.231
2.203TyrIle: 2.203 ± 0.276
1.943TyrLys: 1.943 ± 0.299
2.915TyrLeu: 2.915 ± 0.47
0.972TyrMet: 0.972 ± 0.232
2.203TyrAsn: 2.203 ± 0.348
0.777TyrPro: 0.777 ± 0.275
1.231TyrGln: 1.231 ± 0.287
1.879TyrArg: 1.879 ± 0.272
2.526TyrSer: 2.526 ± 0.374
2.98TyrThr: 2.98 ± 0.48
2.397TyrVal: 2.397 ± 0.33
0.389TyrTrp: 0.389 ± 0.156
1.684TyrTyr: 1.684 ± 0.302
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 49 proteins (15438 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski