Amino acid dipepetide frequency for Aythya fuligula (Tufted duck) (Anas fuligula)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.389AlaAla: 7.389 ± 0.044	1.269AlaCys: 1.269 ± 0.011	3.142AlaAsp: 3.142 ± 0.015	5.277AlaGlu: 5.277 ± 0.027	2.413AlaPhe: 2.413 ± 0.015	4.543AlaGly: 4.543 ± 0.025	1.359AlaHis: 1.359 ± 0.009	2.829AlaIle: 2.829 ± 0.015	3.725AlaLys: 3.725 ± 0.02	6.623AlaLeu: 6.623 ± 0.029	1.512AlaMet: 1.512 ± 0.01	2.254AlaAsn: 2.254 ± 0.012	3.647AlaPro: 3.647 ± 0.027	3.109AlaGln: 3.109 ± 0.02	3.393AlaArg: 3.393 ± 0.018	5.743AlaSer: 5.743 ± 0.028	3.501AlaThr: 3.501 ± 0.02	4.948AlaVal: 4.948 ± 0.022	0.685AlaTrp: 0.685 ± 0.008	1.523AlaTyr: 1.523 ± 0.011	0.002AlaXaa: 0.002 ± 0.0
Cys	1.143CysAla: 1.143 ± 0.011	0.558CysCys: 0.558 ± 0.009	1.015CysAsp: 1.015 ± 0.013	1.282CysGlu: 1.282 ± 0.014	0.788CysPhe: 0.788 ± 0.008	1.37CysGly: 1.37 ± 0.015	0.597CysHis: 0.597 ± 0.007	1.008CysIle: 1.008 ± 0.01	1.187CysLys: 1.187 ± 0.011	1.944CysLeu: 1.944 ± 0.014	0.42CysMet: 0.42 ± 0.005	0.829CysAsn: 0.829 ± 0.009	1.159CysPro: 1.159 ± 0.015	0.985CysGln: 0.985 ± 0.011	1.182CysArg: 1.182 ± 0.012	1.925CysSer: 1.925 ± 0.017	1.082CysThr: 1.082 ± 0.012	1.203CysVal: 1.203 ± 0.012	0.242CysTrp: 0.242 ± 0.004	0.579CysTyr: 0.579 ± 0.006	0.001CysXaa: 0.001 ± 0.0
Asp	3.034AspAla: 3.034 ± 0.014	1.043AspCys: 1.043 ± 0.011	2.959AspAsp: 2.959 ± 0.018	3.851AspGlu: 3.851 ± 0.02	2.13AspPhe: 2.13 ± 0.012	3.47AspGly: 3.47 ± 0.02	1.145AspHis: 1.145 ± 0.008	2.768AspIle: 2.768 ± 0.015	2.822AspLys: 2.822 ± 0.018	4.919AspLeu: 4.919 ± 0.019	1.152AspMet: 1.152 ± 0.009	1.869AspAsn: 1.869 ± 0.013	2.739AspPro: 2.739 ± 0.016	1.897AspGln: 1.897 ± 0.012	2.448AspArg: 2.448 ± 0.014	4.429AspSer: 4.429 ± 0.025	2.629AspThr: 2.629 ± 0.015	3.187AspVal: 3.187 ± 0.018	0.575AspTrp: 0.575 ± 0.006	1.591AspTyr: 1.591 ± 0.011	0.002AspXaa: 0.002 ± 0.0
Glu	5.102GluAla: 5.102 ± 0.026	1.23GluCys: 1.23 ± 0.017	4.699GluAsp: 4.699 ± 0.022	8.658GluGlu: 8.658 ± 0.052	2.041GluPhe: 2.041 ± 0.012	4.125GluGly: 4.125 ± 0.023	1.601GluHis: 1.601 ± 0.012	3.474GluIle: 3.474 ± 0.017	5.88GluLys: 5.88 ± 0.042	6.638GluLeu: 6.638 ± 0.038	1.847GluMet: 1.847 ± 0.014	3.411GluAsn: 3.411 ± 0.018	3.057GluPro: 3.057 ± 0.023	3.498GluGln: 3.498 ± 0.024	4.264GluArg: 4.264 ± 0.025	4.856GluSer: 4.856 ± 0.025	3.713GluThr: 3.713 ± 0.019	4.279GluVal: 4.279 ± 0.02	0.678GluTrp: 0.678 ± 0.006	1.747GluTyr: 1.747 ± 0.013	0.003GluXaa: 0.003 ± 0.0
Phe	1.997PheAla: 1.997 ± 0.014	0.847PheCys: 0.847 ± 0.008	1.699PheAsp: 1.699 ± 0.01	2.012PheGlu: 2.012 ± 0.011	1.478PhePhe: 1.478 ± 0.013	2.105PheGly: 2.105 ± 0.015	0.972PheHis: 0.972 ± 0.008	1.811PheIle: 1.811 ± 0.013	1.782PheLys: 1.782 ± 0.013	3.599PheLeu: 3.599 ± 0.02	0.748PheMet: 0.748 ± 0.007	1.368PheAsn: 1.368 ± 0.011	1.857PhePro: 1.857 ± 0.012	1.708PheGln: 1.708 ± 0.012	1.779PheArg: 1.779 ± 0.014	3.162PheSer: 3.162 ± 0.017	1.959PheThr: 1.959 ± 0.014	2.141PheVal: 2.141 ± 0.014	0.442PheTrp: 0.442 ± 0.006	1.124PheTyr: 1.124 ± 0.01	0.001PheXaa: 0.001 ± 0.0
Gly	4.107GlyAla: 4.107 ± 0.026	1.193GlyCys: 1.193 ± 0.013	3.155GlyAsp: 3.155 ± 0.018	3.995GlyGlu: 3.995 ± 0.025	2.316GlyPhe: 2.316 ± 0.016	4.761GlyGly: 4.761 ± 0.04	1.509GlyHis: 1.509 ± 0.011	2.753GlyIle: 2.753 ± 0.016	3.765GlyLys: 3.765 ± 0.02	5.165GlyLeu: 5.165 ± 0.029	1.368GlyMet: 1.368 ± 0.012	2.537GlyAsn: 2.537 ± 0.015	3.305GlyPro: 3.305 ± 0.039	2.689GlyGln: 2.689 ± 0.017	3.523GlyArg: 3.523 ± 0.02	5.77GlySer: 5.77 ± 0.029	3.575GlyThr: 3.575 ± 0.021	3.388GlyVal: 3.388 ± 0.02	0.747GlyTrp: 0.747 ± 0.009	1.792GlyTyr: 1.792 ± 0.015	0.003GlyXaa: 0.003 ± 0.0
His	1.357HisAla: 1.357 ± 0.01	0.666HisCys: 0.666 ± 0.008	0.95HisAsp: 0.95 ± 0.009	1.393HisGlu: 1.393 ± 0.01	0.986HisPhe: 0.986 ± 0.009	1.51HisGly: 1.51 ± 0.012	0.907HisHis: 0.907 ± 0.012	1.253HisIle: 1.253 ± 0.01	1.332HisLys: 1.332 ± 0.011	2.637HisLeu: 2.637 ± 0.016	0.557HisMet: 0.557 ± 0.005	0.935HisAsn: 0.935 ± 0.008	1.499HisPro: 1.499 ± 0.011	1.184HisGln: 1.184 ± 0.011	1.462HisArg: 1.462 ± 0.011	2.244HisSer: 2.244 ± 0.014	1.299HisThr: 1.299 ± 0.01	1.481HisVal: 1.481 ± 0.009	0.285HisTrp: 0.285 ± 0.004	0.835HisTyr: 0.835 ± 0.007	0.001HisXaa: 0.001 ± 0.0
Ile	2.835IleAla: 2.835 ± 0.014	1.04IleCys: 1.04 ± 0.009	2.216IleAsp: 2.216 ± 0.013	2.827IleGlu: 2.827 ± 0.017	1.795IlePhe: 1.795 ± 0.014	2.28IleGly: 2.28 ± 0.014	1.239IleHis: 1.239 ± 0.008	2.423IleIle: 2.423 ± 0.017	2.849IleLys: 2.849 ± 0.017	4.388IleLeu: 4.388 ± 0.019	0.989IleMet: 0.989 ± 0.008	2.031IleAsn: 2.031 ± 0.013	2.689IlePro: 2.689 ± 0.015	2.418IleGln: 2.418 ± 0.013	2.4IleArg: 2.4 ± 0.013	3.92IleSer: 3.92 ± 0.017	2.746IleThr: 2.746 ± 0.017	2.61IleVal: 2.61 ± 0.017	0.483IleTrp: 0.483 ± 0.007	1.387IleTyr: 1.387 ± 0.011	0.001IleXaa: 0.001 ± 0.0
Lys	4.059LysAla: 4.059 ± 0.022	1.114LysCys: 1.114 ± 0.01	3.468LysAsp: 3.468 ± 0.021	5.701LysGlu: 5.701 ± 0.037	1.704LysPhe: 1.704 ± 0.01	3.34LysGly: 3.34 ± 0.025	1.508LysHis: 1.508 ± 0.011	2.927LysIle: 2.927 ± 0.017	5.222LysLys: 5.222 ± 0.031	5.469LysLeu: 5.469 ± 0.024	1.536LysMet: 1.536 ± 0.011	2.64LysAsn: 2.64 ± 0.014	3.197LysPro: 3.197 ± 0.022	3.058LysGln: 3.058 ± 0.021	3.529LysArg: 3.529 ± 0.02	4.36LysSer: 4.36 ± 0.024	3.385LysThr: 3.385 ± 0.016	3.614LysVal: 3.614 ± 0.02	0.613LysTrp: 0.613 ± 0.007	1.689LysTyr: 1.689 ± 0.013	0.003LysXaa: 0.003 ± 0.001
Leu	6.287LeuAla: 6.287 ± 0.029	1.976LeuCys: 1.976 ± 0.014	4.685LeuAsp: 4.685 ± 0.017	7.217LeuGlu: 7.217 ± 0.04	3.052LeuPhe: 3.052 ± 0.023	5.079LeuGly: 5.079 ± 0.024	2.635LeuHis: 2.635 ± 0.014	3.743LeuIle: 3.743 ± 0.02	6.115LeuLys: 6.115 ± 0.028	9.833LeuLeu: 9.833 ± 0.048	1.926LeuMet: 1.926 ± 0.012	3.694LeuAsn: 3.694 ± 0.017	5.607LeuPro: 5.607 ± 0.026	5.764LeuGln: 5.764 ± 0.034	5.442LeuArg: 5.442 ± 0.025	7.748LeuSer: 7.748 ± 0.029	4.736LeuThr: 4.736 ± 0.019	4.989LeuVal: 4.989 ± 0.024	0.971LeuTrp: 0.971 ± 0.009	2.51LeuTyr: 2.51 ± 0.015	0.003LeuXaa: 0.003 ± 0.001
Met	1.813MetAla: 1.813 ± 0.012	0.385MetCys: 0.385 ± 0.005	1.275MetAsp: 1.275 ± 0.008	1.976MetGlu: 1.976 ± 0.014	0.739MetPhe: 0.739 ± 0.007	1.27MetGly: 1.27 ± 0.012	0.492MetHis: 0.492 ± 0.006	0.859MetIle: 0.859 ± 0.008	1.574MetLys: 1.574 ± 0.012	1.962MetLeu: 1.962 ± 0.012	0.6MetMet: 0.6 ± 0.007	0.957MetAsn: 0.957 ± 0.009	1.122MetPro: 1.122 ± 0.009	1.076MetGln: 1.076 ± 0.01	1.077MetArg: 1.077 ± 0.008	1.641MetSer: 1.641 ± 0.01	1.106MetThr: 1.106 ± 0.008	1.365MetVal: 1.365 ± 0.009	0.241MetTrp: 0.241 ± 0.004	0.595MetTyr: 0.595 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.38AsnAla: 2.38 ± 0.012	0.858AsnCys: 0.858 ± 0.01	1.691AsnAsp: 1.691 ± 0.011	2.533AsnGlu: 2.533 ± 0.014	1.454AsnPhe: 1.454 ± 0.011	2.798AsnGly: 2.798 ± 0.02	0.973AsnHis: 0.973 ± 0.008	2.281AsnIle: 2.281 ± 0.015	2.498AsnLys: 2.498 ± 0.015	3.817AsnLeu: 3.817 ± 0.02	0.986AsnMet: 0.986 ± 0.008	1.772AsnAsn: 1.772 ± 0.013	2.187AsnPro: 2.187 ± 0.016	1.79AsnGln: 1.79 ± 0.012	1.957AsnArg: 1.957 ± 0.011	3.483AsnSer: 3.483 ± 0.02	2.205AsnThr: 2.205 ± 0.013	2.397AsnVal: 2.397 ± 0.014	0.434AsnTrp: 0.434 ± 0.005	1.185AsnTyr: 1.185 ± 0.01	0.002AsnXaa: 0.002 ± 0.0
Pro	4.731ProAla: 4.731 ± 0.027	1.02ProCys: 1.02 ± 0.014	2.717ProAsp: 2.717 ± 0.015	4.13ProGlu: 4.13 ± 0.022	1.782ProPhe: 1.782 ± 0.012	4.554ProGly: 4.554 ± 0.059	1.34ProHis: 1.34 ± 0.012	1.942ProIle: 1.942 ± 0.015	2.871ProLys: 2.871 ± 0.022	4.798ProLeu: 4.798 ± 0.02	0.994ProMet: 0.994 ± 0.009	1.899ProAsn: 1.899 ± 0.014	5.643ProPro: 5.643 ± 0.057	2.711ProGln: 2.711 ± 0.021	2.916ProArg: 2.916 ± 0.017	5.497ProSer: 5.497 ± 0.032	2.947ProThr: 2.947 ± 0.021	3.879ProVal: 3.879 ± 0.022	0.532ProTrp: 0.532 ± 0.007	1.441ProTyr: 1.441 ± 0.013	0.002ProXaa: 0.002 ± 0.0
Gln	3.307GlnAla: 3.307 ± 0.017	0.918GlnCys: 0.918 ± 0.011	2.321GlnAsp: 2.321 ± 0.013	3.956GlnGlu: 3.956 ± 0.029	1.42GlnPhe: 1.42 ± 0.009	2.671GlnGly: 2.671 ± 0.018	1.374GlnHis: 1.374 ± 0.012	2.137GlnIle: 2.137 ± 0.012	3.194GlnLys: 3.194 ± 0.021	4.697GlnLeu: 4.697 ± 0.028	1.176GlnMet: 1.176 ± 0.009	2.064GlnAsn: 2.064 ± 0.013	2.809GlnPro: 2.809 ± 0.022	3.586GlnGln: 3.586 ± 0.035	2.855GlnArg: 2.855 ± 0.017	3.454GlnSer: 3.454 ± 0.023	2.502GlnThr: 2.502 ± 0.016	2.721GlnVal: 2.721 ± 0.014	0.517GlnTrp: 0.517 ± 0.006	1.291GlnTyr: 1.291 ± 0.01	0.001GlnXaa: 0.001 ± 0.0
Arg	3.507ArgAla: 3.507 ± 0.019	1.125ArgCys: 1.125 ± 0.014	2.744ArgAsp: 2.744 ± 0.015	3.997ArgGlu: 3.997 ± 0.021	1.757ArgPhe: 1.757 ± 0.012	3.28ArgGly: 3.28 ± 0.021	1.43ArgHis: 1.43 ± 0.01	2.475ArgIle: 2.475 ± 0.012	3.738ArgLys: 3.738 ± 0.019	5.048ArgLeu: 5.048 ± 0.023	1.213ArgMet: 1.213 ± 0.009	2.23ArgAsn: 2.23 ± 0.013	2.797ArgPro: 2.797 ± 0.017	2.686ArgGln: 2.686 ± 0.018	4.279ArgArg: 4.279 ± 0.027	4.469ArgSer: 4.469 ± 0.027	2.825ArgThr: 2.825 ± 0.017	2.942ArgVal: 2.942 ± 0.017	0.613ArgTrp: 0.613 ± 0.007	1.51ArgTyr: 1.51 ± 0.011	0.002ArgXaa: 0.002 ± 0.0
Ser	5.596SerAla: 5.596 ± 0.023	1.752SerCys: 1.752 ± 0.013	4.203SerAsp: 4.203 ± 0.023	5.527SerGlu: 5.527 ± 0.027	2.921SerPhe: 2.921 ± 0.015	5.353SerGly: 5.353 ± 0.024	2.019SerHis: 2.019 ± 0.014	3.502SerIle: 3.502 ± 0.017	4.553SerLys: 4.553 ± 0.024	7.904SerLeu: 7.904 ± 0.031	1.711SerMet: 1.711 ± 0.011	3.093SerAsn: 3.093 ± 0.018	6.097SerPro: 6.097 ± 0.036	3.942SerGln: 3.942 ± 0.021	4.474SerArg: 4.474 ± 0.024	10.246SerSer: 10.246 ± 0.064	4.977SerThr: 4.977 ± 0.036	5.069SerVal: 5.069 ± 0.023	0.936SerTrp: 0.936 ± 0.009	2.156SerTyr: 2.156 ± 0.014	0.002SerXaa: 0.002 ± 0.0
Thr	4.016ThrAla: 4.016 ± 0.023	1.22ThrCys: 1.22 ± 0.015	2.737ThrAsp: 2.737 ± 0.014	3.957ThrGlu: 3.957 ± 0.019	1.953ThrPhe: 1.953 ± 0.012	3.414ThrGly: 3.414 ± 0.02	1.16ThrHis: 1.16 ± 0.009	2.443ThrIle: 2.443 ± 0.016	2.936ThrLys: 2.936 ± 0.017	4.991ThrLeu: 4.991 ± 0.018	1.137ThrMet: 1.137 ± 0.009	1.921ThrAsn: 1.921 ± 0.012	3.565ThrPro: 3.565 ± 0.026	2.235ThrGln: 2.235 ± 0.013	2.421ThrArg: 2.421 ± 0.013	4.976ThrSer: 4.976 ± 0.033	3.263ThrThr: 3.263 ± 0.038	3.956ThrVal: 3.956 ± 0.023	0.637ThrTrp: 0.637 ± 0.007	1.442ThrTyr: 1.442 ± 0.01	0.002ThrXaa: 0.002 ± 0.0
Val	4.115ValAla: 4.115 ± 0.02	1.382ValCys: 1.382 ± 0.013	2.976ValAsp: 2.976 ± 0.015	3.997ValGlu: 3.997 ± 0.021	2.302ValPhe: 2.302 ± 0.015	3.157ValGly: 3.157 ± 0.017	1.486ValHis: 1.486 ± 0.01	2.937ValIle: 2.937 ± 0.017	3.74ValLys: 3.74 ± 0.021	5.915ValLeu: 5.915 ± 0.027	1.327ValMet: 1.327 ± 0.01	2.474ValAsn: 2.474 ± 0.014	3.678ValPro: 3.678 ± 0.023	2.849ValGln: 2.849 ± 0.015	2.969ValArg: 2.969 ± 0.016	4.934ValSer: 4.934 ± 0.024	3.817ValThr: 3.817 ± 0.027	3.994ValVal: 3.994 ± 0.022	0.648ValTrp: 0.648 ± 0.008	1.612ValTyr: 1.612 ± 0.012	0.001ValXaa: 0.001 ± 0.0
Trp	0.63TrpAla: 0.63 ± 0.007	0.221TrpCys: 0.221 ± 0.004	0.613TrpAsp: 0.613 ± 0.007	0.749TrpGlu: 0.749 ± 0.008	0.399TrpPhe: 0.399 ± 0.005	0.61TrpGly: 0.61 ± 0.011	0.287TrpHis: 0.287 ± 0.004	0.531TrpIle: 0.531 ± 0.007	0.764TrpLys: 0.764 ± 0.008	1.094TrpLeu: 1.094 ± 0.009	0.305TrpMet: 0.305 ± 0.005	0.513TrpAsn: 0.513 ± 0.006	0.429TrpPro: 0.429 ± 0.006	0.513TrpGln: 0.513 ± 0.005	0.646TrpArg: 0.646 ± 0.006	0.813TrpSer: 0.813 ± 0.01	0.596TrpThr: 0.596 ± 0.007	0.586TrpVal: 0.586 ± 0.006	0.168TrpTrp: 0.168 ± 0.003	0.333TrpTyr: 0.333 ± 0.005	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.477TyrAla: 1.477 ± 0.011	0.68TyrCys: 0.68 ± 0.007	1.39TyrAsp: 1.39 ± 0.011	1.763TyrGlu: 1.763 ± 0.012	1.159TyrPhe: 1.159 ± 0.01	1.726TyrGly: 1.726 ± 0.013	0.741TyrHis: 0.741 ± 0.007	1.47TyrIle: 1.47 ± 0.013	1.586TyrLys: 1.586 ± 0.013	2.571TyrLeu: 2.571 ± 0.014	0.62TyrMet: 0.62 ± 0.007	1.189TyrAsn: 1.189 ± 0.01	1.257TyrPro: 1.257 ± 0.01	1.274TyrGln: 1.274 ± 0.009	1.646TyrArg: 1.646 ± 0.013	2.359TyrSer: 2.359 ± 0.015	1.519TyrThr: 1.519 ± 0.012	1.56TyrVal: 1.56 ± 0.012	0.355TyrTrp: 0.355 ± 0.006	0.965TyrTyr: 0.965 ± 0.009	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.002XaaCys: 0.002 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.002XaaPhe: 0.002 ± 0.0	0.003XaaGly: 0.003 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.003XaaLys: 0.003 ± 0.001	0.003XaaLeu: 0.003 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.002XaaAsn: 0.002 ± 0.0	0.003XaaPro: 0.003 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.002XaaSer: 0.002 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 24034 proteins (17668086 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---