Amino acid dipepetide frequency for Phytophthora sojae (strain P6497) (Soybean stem and root rot agent) (Phytophthora megasperma f. sp. glycines)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.839AlaAla: 11.839 ± 0.07
1.392AlaCys: 1.392 ± 0.02
4.815AlaAsp: 4.815 ± 0.028
5.582AlaGlu: 5.582 ± 0.035
3.376AlaPhe: 3.376 ± 0.023
5.787AlaGly: 5.787 ± 0.096
1.889AlaHis: 1.889 ± 0.016
3.754AlaIle: 3.754 ± 0.025
4.702AlaLys: 4.702 ± 0.029
9.074AlaLeu: 9.074 ± 0.056
2.385AlaMet: 2.385 ± 0.021
3.02AlaAsn: 3.02 ± 0.022
4.66AlaPro: 4.66 ± 0.038
3.745AlaGln: 3.745 ± 0.026
5.681AlaArg: 5.681 ± 0.033
7.965AlaSer: 7.965 ± 0.045
6.041AlaThr: 6.041 ± 0.041
6.734AlaVal: 6.734 ± 0.049
1.063AlaTrp: 1.063 ± 0.012
2.051AlaTyr: 2.051 ± 0.017
0.0AlaXaa: 0.0 ± 0.0
Cys
1.434CysAla: 1.434 ± 0.017
0.442CysCys: 0.442 ± 0.009
0.92CysAsp: 0.92 ± 0.016
0.955CysGlu: 0.955 ± 0.013
0.688CysPhe: 0.688 ± 0.009
1.272CysGly: 1.272 ± 0.015
0.393CysHis: 0.393 ± 0.006
0.781CysIle: 0.781 ± 0.01
0.708CysLys: 0.708 ± 0.008
1.434CysLeu: 1.434 ± 0.031
0.436CysMet: 0.436 ± 0.026
0.529CysAsn: 0.529 ± 0.009
0.84CysPro: 0.84 ± 0.018
0.562CysGln: 0.562 ± 0.009
1.091CysArg: 1.091 ± 0.016
1.495CysSer: 1.495 ± 0.018
1.035CysThr: 1.035 ± 0.014
1.306CysVal: 1.306 ± 0.014
0.28CysTrp: 0.28 ± 0.007
0.499CysTyr: 0.499 ± 0.011
0.0CysXaa: 0.0 ± 0.0
Asp
5.761AspAla: 5.761 ± 0.029
0.847AspCys: 0.847 ± 0.011
4.408AspAsp: 4.408 ± 0.035
4.71AspGlu: 4.71 ± 0.03
2.174AspPhe: 2.174 ± 0.015
4.01AspGly: 4.01 ± 0.029
1.104AspHis: 1.104 ± 0.011
2.347AspIle: 2.347 ± 0.019
2.399AspLys: 2.399 ± 0.019
4.784AspLeu: 4.784 ± 0.051
1.287AspMet: 1.287 ± 0.017
1.777AspAsn: 1.777 ± 0.017
2.665AspPro: 2.665 ± 0.021
1.827AspGln: 1.827 ± 0.014
2.918AspArg: 2.918 ± 0.026
4.161AspSer: 4.161 ± 0.028
2.871AspThr: 2.871 ± 0.038
4.357AspVal: 4.357 ± 0.029
0.678AspTrp: 0.678 ± 0.011
1.531AspTyr: 1.531 ± 0.015
0.0AspXaa: 0.0 ± 0.0
Glu
6.039GluAla: 6.039 ± 0.035
0.928GluCys: 0.928 ± 0.012
4.141GluAsp: 4.141 ± 0.029
5.629GluGlu: 5.629 ± 0.047
2.189GluPhe: 2.189 ± 0.016
3.395GluGly: 3.395 ± 0.025
1.486GluHis: 1.486 ± 0.015
2.648GluIle: 2.648 ± 0.021
3.473GluLys: 3.473 ± 0.032
6.498GluLeu: 6.498 ± 0.037
1.674GluMet: 1.674 ± 0.015
2.136GluAsn: 2.136 ± 0.017
2.355GluPro: 2.355 ± 0.022
2.903GluGln: 2.903 ± 0.039
4.335GluArg: 4.335 ± 0.028
4.1GluSer: 4.1 ± 0.029
3.312GluThr: 3.312 ± 0.038
4.271GluVal: 4.271 ± 0.036
0.859GluTrp: 0.859 ± 0.01
1.643GluTyr: 1.643 ± 0.013
0.0GluXaa: 0.0 ± 0.0
Phe
3.208PheAla: 3.208 ± 0.02
0.745PheCys: 0.745 ± 0.009
2.231PheAsp: 2.231 ± 0.02
2.191PheGlu: 2.191 ± 0.017
1.58PhePhe: 1.58 ± 0.015
2.751PheGly: 2.751 ± 0.025
0.928PheHis: 0.928 ± 0.011
1.502PheIle: 1.502 ± 0.014
1.53PheLys: 1.53 ± 0.015
3.476PheLeu: 3.476 ± 0.023
0.878PheMet: 0.878 ± 0.009
1.293PheAsn: 1.293 ± 0.013
1.662PhePro: 1.662 ± 0.017
1.449PheGln: 1.449 ± 0.014
2.132PheArg: 2.132 ± 0.017
2.893PheSer: 2.893 ± 0.021
2.041PheThr: 2.041 ± 0.016
2.98PheVal: 2.98 ± 0.022
0.513PheTrp: 0.513 ± 0.012
1.172PheTyr: 1.172 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
5.678GlyAla: 5.678 ± 0.05
1.201GlyCys: 1.201 ± 0.02
3.907GlyAsp: 3.907 ± 0.026
3.615GlyGlu: 3.615 ± 0.022
2.455GlyPhe: 2.455 ± 0.02
5.488GlyGly: 5.488 ± 0.128
1.55GlyHis: 1.55 ± 0.018
2.69GlyIle: 2.69 ± 0.018
3.177GlyLys: 3.177 ± 0.025
4.964GlyLeu: 4.964 ± 0.025
1.489GlyMet: 1.489 ± 0.019
2.296GlyAsn: 2.296 ± 0.02
2.203GlyPro: 2.203 ± 0.018
2.026GlyGln: 2.026 ± 0.017
3.908GlyArg: 3.908 ± 0.126
5.762GlySer: 5.762 ± 0.073
3.401GlyThr: 3.401 ± 0.029
4.754GlyVal: 4.754 ± 0.035
0.85GlyTrp: 0.85 ± 0.01
1.912GlyTyr: 1.912 ± 0.02
0.0GlyXaa: 0.0 ± 0.0
His
2.039HisAla: 2.039 ± 0.016
0.442HisCys: 0.442 ± 0.008
1.239HisAsp: 1.239 ± 0.014
1.469HisGlu: 1.469 ± 0.014
1.014HisPhe: 1.014 ± 0.011
1.639HisGly: 1.639 ± 0.015
0.731HisHis: 0.731 ± 0.012
0.902HisIle: 0.902 ± 0.03
0.947HisLys: 0.947 ± 0.012
2.257HisLeu: 2.257 ± 0.019
0.471HisMet: 0.471 ± 0.007
0.698HisAsn: 0.698 ± 0.011
1.237HisPro: 1.237 ± 0.012
0.963HisGln: 0.963 ± 0.012
1.593HisArg: 1.593 ± 0.015
1.685HisSer: 1.685 ± 0.014
1.071HisThr: 1.071 ± 0.011
1.743HisVal: 1.743 ± 0.016
0.349HisTrp: 0.349 ± 0.006
0.698HisTyr: 0.698 ± 0.025
0.0HisXaa: 0.0 ± 0.0
Ile
3.773IleAla: 3.773 ± 0.04
0.765IleCys: 0.765 ± 0.009
2.401IleAsp: 2.401 ± 0.021
2.429IleGlu: 2.429 ± 0.02
1.556IlePhe: 1.556 ± 0.016
2.455IleGly: 2.455 ± 0.027
0.923IleHis: 0.923 ± 0.011
1.589IleIle: 1.589 ± 0.015
1.868IleLys: 1.868 ± 0.016
3.433IleLeu: 3.433 ± 0.031
0.93IleMet: 0.93 ± 0.011
1.397IleAsn: 1.397 ± 0.016
2.074IlePro: 2.074 ± 0.019
1.593IleGln: 1.593 ± 0.015
2.425IleArg: 2.425 ± 0.019
3.01IleSer: 3.01 ± 0.019
2.197IleThr: 2.197 ± 0.022
3.063IleVal: 3.063 ± 0.024
0.5IleTrp: 0.5 ± 0.008
1.107IleTyr: 1.107 ± 0.015
0.0IleXaa: 0.0 ± 0.0
Lys
4.303LysAla: 4.303 ± 0.03
0.767LysCys: 0.767 ± 0.011
2.372LysAsp: 2.372 ± 0.023
3.121LysGlu: 3.121 ± 0.026
1.638LysPhe: 1.638 ± 0.016
2.362LysGly: 2.362 ± 0.016
1.214LysHis: 1.214 ± 0.015
1.924LysIle: 1.924 ± 0.016
3.724LysLys: 3.724 ± 0.036
4.987LysLeu: 4.987 ± 0.03
1.244LysMet: 1.244 ± 0.013
1.75LysAsn: 1.75 ± 0.017
2.227LysPro: 2.227 ± 0.018
2.211LysGln: 2.211 ± 0.019
3.801LysArg: 3.801 ± 0.027
3.294LysSer: 3.294 ± 0.026
2.966LysThr: 2.966 ± 0.022
2.938LysVal: 2.938 ± 0.021
0.754LysTrp: 0.754 ± 0.009
1.458LysTyr: 1.458 ± 0.015
0.0LysXaa: 0.0 ± 0.0
Leu
8.555LeuAla: 8.555 ± 0.046
1.617LeuCys: 1.617 ± 0.014
5.21LeuAsp: 5.21 ± 0.055
6.202LeuGlu: 6.202 ± 0.039
3.425LeuPhe: 3.425 ± 0.025
5.255LeuGly: 5.255 ± 0.039
2.494LeuHis: 2.494 ± 0.018
3.103LeuIle: 3.103 ± 0.024
4.455LeuLys: 4.455 ± 0.031
9.856LeuLeu: 9.856 ± 0.057
2.12LeuMet: 2.12 ± 0.015
2.969LeuAsn: 2.969 ± 0.02
4.762LeuPro: 4.762 ± 0.06
4.667LeuGln: 4.667 ± 0.038
6.751LeuArg: 6.751 ± 0.039
7.029LeuSer: 7.029 ± 0.036
4.862LeuThr: 4.862 ± 0.03
6.605LeuVal: 6.605 ± 0.03
1.1LeuTrp: 1.1 ± 0.012
2.327LeuTyr: 2.327 ± 0.016
0.0LeuXaa: 0.0 ± 0.0
Met
2.285MetAla: 2.285 ± 0.017
0.379MetCys: 0.379 ± 0.005
1.447MetAsp: 1.447 ± 0.016
1.711MetGlu: 1.711 ± 0.017
0.776MetPhe: 0.776 ± 0.01
1.336MetGly: 1.336 ± 0.013
0.558MetHis: 0.558 ± 0.007
0.894MetIle: 0.894 ± 0.01
1.345MetLys: 1.345 ± 0.014
2.455MetLeu: 2.455 ± 0.019
0.674MetMet: 0.674 ± 0.01
0.862MetAsn: 0.862 ± 0.012
1.084MetPro: 1.084 ± 0.011
1.088MetGln: 1.088 ± 0.034
1.462MetArg: 1.462 ± 0.015
1.695MetSer: 1.695 ± 0.015
1.393MetThr: 1.393 ± 0.015
1.592MetVal: 1.592 ± 0.022
0.308MetTrp: 0.308 ± 0.006
0.617MetTyr: 0.617 ± 0.009
0.0MetXaa: 0.0 ± 0.0
Asn
3.451AsnAla: 3.451 ± 0.03
0.604AsnCys: 0.604 ± 0.009
1.827AsnAsp: 1.827 ± 0.016
2.015AsnGlu: 2.015 ± 0.017
1.27AsnPhe: 1.27 ± 0.012
2.708AsnGly: 2.708 ± 0.027
0.692AsnHis: 0.692 ± 0.009
1.419AsnIle: 1.419 ± 0.013
1.503AsnLys: 1.503 ± 0.014
2.799AsnLeu: 2.799 ± 0.018
0.842AsnMet: 0.842 ± 0.009
1.276AsnAsn: 1.276 ± 0.016
1.745AsnPro: 1.745 ± 0.014
1.228AsnGln: 1.228 ± 0.014
1.879AsnArg: 1.879 ± 0.027
2.546AsnSer: 2.546 ± 0.021
1.789AsnThr: 1.789 ± 0.017
2.458AsnVal: 2.458 ± 0.017
0.459AsnTrp: 0.459 ± 0.006
0.954AsnTyr: 0.954 ± 0.013
0.0AsnXaa: 0.0 ± 0.0
Pro
4.791ProAla: 4.791 ± 0.036
0.627ProCys: 0.627 ± 0.009
2.482ProAsp: 2.482 ± 0.019
3.126ProGlu: 3.126 ± 0.023
1.656ProPhe: 1.656 ± 0.016
2.799ProGly: 2.799 ± 0.022
1.065ProHis: 1.065 ± 0.029
1.703ProIle: 1.703 ± 0.035
2.202ProLys: 2.202 ± 0.018
4.013ProLeu: 4.013 ± 0.026
1.06ProMet: 1.06 ± 0.011
1.519ProAsn: 1.519 ± 0.015
3.548ProPro: 3.548 ± 0.034
1.813ProGln: 1.813 ± 0.016
3.093ProArg: 3.093 ± 0.024
4.582ProSer: 4.582 ± 0.033
3.447ProThr: 3.447 ± 0.032
3.345ProVal: 3.345 ± 0.024
0.536ProTrp: 0.536 ± 0.008
1.043ProTyr: 1.043 ± 0.011
0.0ProXaa: 0.0 ± 0.0
Gln
3.527GlnAla: 3.527 ± 0.024
0.677GlnCys: 0.677 ± 0.031
1.958GlnAsp: 1.958 ± 0.017
2.697GlnGlu: 2.697 ± 0.025
1.411GlnPhe: 1.411 ± 0.014
1.956GlnGly: 1.956 ± 0.018
1.201GlnHis: 1.201 ± 0.032
1.557GlnIle: 1.557 ± 0.013
1.904GlnLys: 1.904 ± 0.018
4.465GlnLeu: 4.465 ± 0.029
0.991GlnMet: 0.991 ± 0.01
1.232GlnAsn: 1.232 ± 0.012
1.912GlnPro: 1.912 ± 0.017
3.049GlnGln: 3.049 ± 0.035
3.252GlnArg: 3.252 ± 0.026
2.685GlnSer: 2.685 ± 0.021
2.144GlnThr: 2.144 ± 0.031
2.641GlnVal: 2.641 ± 0.019
0.635GlnTrp: 0.635 ± 0.009
1.1GlnTyr: 1.1 ± 0.011
0.0GlnXaa: 0.0 ± 0.0
Arg
5.633ArgAla: 5.633 ± 0.037
1.174ArgCys: 1.174 ± 0.016
3.342ArgAsp: 3.342 ± 0.025
4.111ArgGlu: 4.111 ± 0.036
2.436ArgPhe: 2.436 ± 0.018
3.886ArgGly: 3.886 ± 0.032
1.665ArgHis: 1.665 ± 0.014
2.488ArgIle: 2.488 ± 0.022
3.455ArgLys: 3.455 ± 0.024
6.145ArgLeu: 6.145 ± 0.038
1.525ArgMet: 1.525 ± 0.016
2.088ArgAsn: 2.088 ± 0.016
2.726ArgPro: 2.726 ± 0.024
2.878ArgGln: 2.878 ± 0.024
5.751ArgArg: 5.751 ± 0.045
5.129ArgSer: 5.129 ± 0.04
3.207ArgThr: 3.207 ± 0.023
4.616ArgVal: 4.616 ± 0.071
0.98ArgTrp: 0.98 ± 0.013
1.702ArgTyr: 1.702 ± 0.014
0.0ArgXaa: 0.0 ± 0.0
Ser
7.591SerAla: 7.591 ± 0.048
1.297SerCys: 1.297 ± 0.027
4.569SerAsp: 4.569 ± 0.028
4.358SerGlu: 4.358 ± 0.03
2.901SerPhe: 2.901 ± 0.021
5.647SerGly: 5.647 ± 0.053
1.515SerHis: 1.515 ± 0.015
3.243SerIle: 3.243 ± 0.024
3.681SerLys: 3.681 ± 0.024
6.575SerLeu: 6.575 ± 0.034
1.85SerMet: 1.85 ± 0.017
2.703SerAsn: 2.703 ± 0.026
4.19SerPro: 4.19 ± 0.033
2.534SerGln: 2.534 ± 0.02
4.705SerArg: 4.705 ± 0.035
9.374SerSer: 9.374 ± 0.058
5.525SerThr: 5.525 ± 0.039
5.476SerVal: 5.476 ± 0.036
1.008SerTrp: 1.008 ± 0.012
1.937SerTyr: 1.937 ± 0.017
0.0SerXaa: 0.0 ± 0.0
Thr
5.472ThrAla: 5.472 ± 0.035
1.021ThrCys: 1.021 ± 0.017
2.836ThrAsp: 2.836 ± 0.028
3.117ThrGlu: 3.117 ± 0.048
2.082ThrPhe: 2.082 ± 0.017
3.649ThrGly: 3.649 ± 0.04
1.193ThrHis: 1.193 ± 0.011
2.488ThrIle: 2.488 ± 0.02
2.783ThrLys: 2.783 ± 0.024
5.244ThrLeu: 5.244 ± 0.029
1.351ThrMet: 1.351 ± 0.015
1.983ThrAsn: 1.983 ± 0.022
3.592ThrPro: 3.592 ± 0.043
2.133ThrGln: 2.133 ± 0.017
3.387ThrArg: 3.387 ± 0.026
5.131ThrSer: 5.131 ± 0.038
4.334ThrThr: 4.334 ± 0.054
3.846ThrVal: 3.846 ± 0.032
0.723ThrTrp: 0.723 ± 0.01
1.402ThrTyr: 1.402 ± 0.016
0.0ThrXaa: 0.0 ± 0.0
Val
7.036ValAla: 7.036 ± 0.049
1.335ValCys: 1.335 ± 0.017
4.276ValAsp: 4.276 ± 0.036
4.66ValGlu: 4.66 ± 0.033
2.794ValPhe: 2.794 ± 0.02
4.281ValGly: 4.281 ± 0.044
1.632ValHis: 1.632 ± 0.015
2.783ValIle: 2.783 ± 0.02
3.326ValLys: 3.326 ± 0.023
6.969ValLeu: 6.969 ± 0.04
1.682ValMet: 1.682 ± 0.013
2.388ValAsn: 2.388 ± 0.019
3.402ValPro: 3.402 ± 0.024
2.789ValGln: 2.789 ± 0.02
4.178ValArg: 4.178 ± 0.035
5.23ValSer: 5.23 ± 0.047
3.941ValThr: 3.941 ± 0.031
5.956ValVal: 5.956 ± 0.037
0.858ValTrp: 0.858 ± 0.01
1.904ValTyr: 1.904 ± 0.015
0.0ValXaa: 0.0 ± 0.0
Trp
0.86TrpAla: 0.86 ± 0.01
0.248TrpCys: 0.248 ± 0.006
0.666TrpAsp: 0.666 ± 0.009
0.728TrpGlu: 0.728 ± 0.008
0.53TrpPhe: 0.53 ± 0.008
0.75TrpGly: 0.75 ± 0.011
0.297TrpHis: 0.297 ± 0.006
0.619TrpIle: 0.619 ± 0.009
0.779TrpLys: 0.779 ± 0.01
1.452TrpLeu: 1.452 ± 0.019
0.418TrpMet: 0.418 ± 0.007
0.551TrpAsn: 0.551 ± 0.009
0.439TrpPro: 0.439 ± 0.008
0.515TrpGln: 0.515 ± 0.009
0.956TrpArg: 0.956 ± 0.012
1.017TrpSer: 1.017 ± 0.012
0.795TrpThr: 0.795 ± 0.011
0.817TrpVal: 0.817 ± 0.01
0.223TrpTrp: 0.223 ± 0.006
0.411TrpTyr: 0.411 ± 0.007
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.283TyrAla: 2.283 ± 0.019
0.592TyrCys: 0.592 ± 0.011
1.568TyrAsp: 1.568 ± 0.013
1.587TyrGlu: 1.587 ± 0.013
1.206TyrPhe: 1.206 ± 0.012
1.901TyrGly: 1.901 ± 0.02
0.657TyrHis: 0.657 ± 0.008
1.054TyrIle: 1.054 ± 0.013
1.096TyrLys: 1.096 ± 0.012
2.483TyrLeu: 2.483 ± 0.026
0.654TyrMet: 0.654 ± 0.007
0.999TyrAsn: 0.999 ± 0.011
1.127TyrPro: 1.127 ± 0.011
1.02TyrGln: 1.02 ± 0.011
1.636TyrArg: 1.636 ± 0.016
1.896TyrSer: 1.896 ± 0.017
1.394TyrThr: 1.394 ± 0.017
1.922TyrVal: 1.922 ± 0.017
0.393TyrTrp: 0.393 ± 0.007
0.931TyrTyr: 0.931 ± 0.012
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 25721 proteins (9854020 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski