Amino acid dipepetide frequency for Muricauda pacifica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.879AlaAla: 3.879 ± 0.08
0.525AlaCys: 0.525 ± 0.023
3.169AlaAsp: 3.169 ± 0.051
3.994AlaGlu: 3.994 ± 0.056
3.413AlaPhe: 3.413 ± 0.057
4.044AlaGly: 4.044 ± 0.064
1.142AlaHis: 1.142 ± 0.027
5.169AlaIle: 5.169 ± 0.07
4.341AlaLys: 4.341 ± 0.066
6.529AlaLeu: 6.529 ± 0.078
1.544AlaMet: 1.544 ± 0.041
3.14AlaAsn: 3.14 ± 0.058
2.013AlaPro: 2.013 ± 0.045
2.474AlaGln: 2.474 ± 0.038
2.144AlaArg: 2.144 ± 0.038
4.174AlaSer: 4.174 ± 0.067
3.445AlaThr: 3.445 ± 0.07
3.964AlaVal: 3.964 ± 0.061
0.637AlaTrp: 0.637 ± 0.024
2.398AlaTyr: 2.398 ± 0.049
0.0AlaXaa: 0.0 ± 0.0
Cys
0.435CysAla: 0.435 ± 0.015
0.103CysCys: 0.103 ± 0.009
0.408CysAsp: 0.408 ± 0.017
0.455CysGlu: 0.455 ± 0.022
0.428CysPhe: 0.428 ± 0.02
0.579CysGly: 0.579 ± 0.024
0.18CysHis: 0.18 ± 0.014
0.506CysIle: 0.506 ± 0.02
0.399CysLys: 0.399 ± 0.016
0.674CysLeu: 0.674 ± 0.021
0.164CysMet: 0.164 ± 0.01
0.383CysAsn: 0.383 ± 0.021
0.329CysPro: 0.329 ± 0.02
0.2CysGln: 0.2 ± 0.011
0.219CysArg: 0.219 ± 0.013
0.569CysSer: 0.569 ± 0.02
0.437CysThr: 0.437 ± 0.027
0.419CysVal: 0.419 ± 0.019
0.064CysTrp: 0.064 ± 0.007
0.27CysTyr: 0.27 ± 0.017
0.0CysXaa: 0.0 ± 0.0
Asp
3.529AspAla: 3.529 ± 0.056
0.394AspCys: 0.394 ± 0.019
3.119AspAsp: 3.119 ± 0.069
3.918AspGlu: 3.918 ± 0.065
3.917AspPhe: 3.917 ± 0.053
4.248AspGly: 4.248 ± 0.087
0.87AspHis: 0.87 ± 0.03
4.247AspIle: 4.247 ± 0.058
3.598AspLys: 3.598 ± 0.068
5.308AspLeu: 5.308 ± 0.064
1.217AspMet: 1.217 ± 0.033
2.963AspAsn: 2.963 ± 0.06
1.767AspPro: 1.767 ± 0.048
1.431AspGln: 1.431 ± 0.043
2.086AspArg: 2.086 ± 0.038
3.683AspSer: 3.683 ± 0.061
2.899AspThr: 2.899 ± 0.054
3.618AspVal: 3.618 ± 0.064
0.837AspTrp: 0.837 ± 0.024
2.655AspTyr: 2.655 ± 0.052
0.0AspXaa: 0.0 ± 0.0
Glu
4.383GluAla: 4.383 ± 0.066
0.313GluCys: 0.313 ± 0.014
3.862GluAsp: 3.862 ± 0.06
5.591GluGlu: 5.591 ± 0.084
3.024GluPhe: 3.024 ± 0.046
4.162GluGly: 4.162 ± 0.063
1.315GluHis: 1.315 ± 0.033
5.397GluIle: 5.397 ± 0.064
5.897GluLys: 5.897 ± 0.092
6.568GluLeu: 6.568 ± 0.078
1.662GluMet: 1.662 ± 0.04
4.626GluAsn: 4.626 ± 0.063
1.868GluPro: 1.868 ± 0.038
2.43GluGln: 2.43 ± 0.05
2.973GluArg: 2.973 ± 0.05
3.763GluSer: 3.763 ± 0.054
3.675GluThr: 3.675 ± 0.058
4.703GluVal: 4.703 ± 0.056
0.722GluTrp: 0.722 ± 0.027
2.466GluTyr: 2.466 ± 0.045
0.0GluXaa: 0.0 ± 0.0
Phe
3.151PheAla: 3.151 ± 0.054
0.429PheCys: 0.429 ± 0.019
3.394PheAsp: 3.394 ± 0.054
3.712PheGlu: 3.712 ± 0.057
3.097PhePhe: 3.097 ± 0.061
4.015PheGly: 4.015 ± 0.063
0.928PheHis: 0.928 ± 0.026
3.515PheIle: 3.515 ± 0.062
3.406PheLys: 3.406 ± 0.052
5.39PheLeu: 5.39 ± 0.077
1.178PheMet: 1.178 ± 0.03
3.055PheAsn: 3.055 ± 0.058
1.843PhePro: 1.843 ± 0.036
1.748PheGln: 1.748 ± 0.041
1.933PheArg: 1.933 ± 0.038
4.107PheSer: 4.107 ± 0.056
3.012PheThr: 3.012 ± 0.054
3.301PheVal: 3.301 ± 0.056
0.676PheTrp: 0.676 ± 0.026
2.155PheTyr: 2.155 ± 0.039
0.0PheXaa: 0.0 ± 0.0
Gly
4.145GlyAla: 4.145 ± 0.065
0.63GlyCys: 0.63 ± 0.035
3.499GlyAsp: 3.499 ± 0.061
4.043GlyGlu: 4.043 ± 0.061
3.994GlyPhe: 3.994 ± 0.055
4.656GlyGly: 4.656 ± 0.079
1.293GlyHis: 1.293 ± 0.037
5.632GlyIle: 5.632 ± 0.074
4.936GlyLys: 4.936 ± 0.074
6.357GlyLeu: 6.357 ± 0.073
1.705GlyMet: 1.705 ± 0.035
3.78GlyAsn: 3.78 ± 0.074
1.615GlyPro: 1.615 ± 0.047
2.104GlyGln: 2.104 ± 0.042
2.447GlyArg: 2.447 ± 0.045
4.18GlySer: 4.18 ± 0.062
4.104GlyThr: 4.104 ± 0.086
4.374GlyVal: 4.374 ± 0.064
0.828GlyTrp: 0.828 ± 0.027
2.848GlyTyr: 2.848 ± 0.05
0.0GlyXaa: 0.0 ± 0.0
His
0.951HisAla: 0.951 ± 0.028
0.177HisCys: 0.177 ± 0.012
0.883HisAsp: 0.883 ± 0.025
1.012HisGlu: 1.012 ± 0.026
1.24HisPhe: 1.24 ± 0.032
1.171HisGly: 1.171 ± 0.03
0.475HisHis: 0.475 ± 0.023
1.402HisIle: 1.402 ± 0.035
1.129HisLys: 1.129 ± 0.032
1.984HisLeu: 1.984 ± 0.046
0.387HisMet: 0.387 ± 0.018
0.816HisAsn: 0.816 ± 0.026
0.913HisPro: 0.913 ± 0.03
0.75HisGln: 0.75 ± 0.026
0.791HisArg: 0.791 ± 0.028
1.104HisSer: 1.104 ± 0.032
0.986HisThr: 0.986 ± 0.027
1.033HisVal: 1.033 ± 0.029
0.269HisTrp: 0.269 ± 0.015
0.79HisTyr: 0.79 ± 0.025
0.0HisXaa: 0.0 ± 0.0
Ile
5.15IleAla: 5.15 ± 0.075
0.574IleCys: 0.574 ± 0.023
4.373IleAsp: 4.373 ± 0.066
5.071IleGlu: 5.071 ± 0.062
3.487IlePhe: 3.487 ± 0.051
4.997IleGly: 4.997 ± 0.073
1.342IleHis: 1.342 ± 0.032
4.797IleIle: 4.797 ± 0.07
4.812IleLys: 4.812 ± 0.069
6.988IleLeu: 6.988 ± 0.092
1.348IleMet: 1.348 ± 0.032
3.959IleAsn: 3.959 ± 0.05
3.277IlePro: 3.277 ± 0.053
2.653IleGln: 2.653 ± 0.046
2.865IleArg: 2.865 ± 0.055
5.349IleSer: 5.349 ± 0.056
4.311IleThr: 4.311 ± 0.086
4.554IleVal: 4.554 ± 0.069
0.782IleTrp: 0.782 ± 0.024
2.515IleTyr: 2.515 ± 0.041
0.0IleXaa: 0.0 ± 0.0
Lys
4.618LysAla: 4.618 ± 0.076
0.304LysCys: 0.304 ± 0.016
4.015LysAsp: 4.015 ± 0.061
6.006LysGlu: 6.006 ± 0.092
2.521LysPhe: 2.521 ± 0.045
4.461LysGly: 4.461 ± 0.071
1.306LysHis: 1.306 ± 0.037
5.072LysIle: 5.072 ± 0.069
6.57LysLys: 6.57 ± 0.098
6.103LysLeu: 6.103 ± 0.086
1.831LysMet: 1.831 ± 0.04
4.396LysAsn: 4.396 ± 0.053
2.322LysPro: 2.322 ± 0.041
2.488LysGln: 2.488 ± 0.05
3.199LysArg: 3.199 ± 0.052
4.461LysSer: 4.461 ± 0.074
4.212LysThr: 4.212 ± 0.064
4.568LysVal: 4.568 ± 0.072
0.823LysTrp: 0.823 ± 0.025
2.618LysTyr: 2.618 ± 0.051
0.0LysXaa: 0.0 ± 0.0
Leu
6.138LeuAla: 6.138 ± 0.08
0.734LeuCys: 0.734 ± 0.025
5.708LeuAsp: 5.708 ± 0.067
6.921LeuGlu: 6.921 ± 0.083
5.278LeuPhe: 5.278 ± 0.083
6.613LeuGly: 6.613 ± 0.087
1.555LeuHis: 1.555 ± 0.04
6.442LeuIle: 6.442 ± 0.078
7.43LeuLys: 7.43 ± 0.101
9.472LeuLeu: 9.472 ± 0.127
2.148LeuMet: 2.148 ± 0.037
5.454LeuAsn: 5.454 ± 0.077
3.73LeuPro: 3.73 ± 0.057
3.384LeuGln: 3.384 ± 0.056
3.731LeuArg: 3.731 ± 0.059
6.916LeuSer: 6.916 ± 0.084
5.09LeuThr: 5.09 ± 0.062
6.079LeuVal: 6.079 ± 0.072
0.945LeuTrp: 0.945 ± 0.028
3.166LeuTyr: 3.166 ± 0.05
0.0LeuXaa: 0.0 ± 0.0
Met
1.743MetAla: 1.743 ± 0.038
0.136MetCys: 0.136 ± 0.011
1.427MetAsp: 1.427 ± 0.038
1.75MetGlu: 1.75 ± 0.036
0.856MetPhe: 0.856 ± 0.026
1.668MetGly: 1.668 ± 0.038
0.425MetHis: 0.425 ± 0.019
1.346MetIle: 1.346 ± 0.033
2.061MetLys: 2.061 ± 0.043
1.997MetLeu: 1.997 ± 0.042
0.58MetMet: 0.58 ± 0.023
1.187MetAsn: 1.187 ± 0.03
0.828MetPro: 0.828 ± 0.022
0.779MetGln: 0.779 ± 0.028
0.913MetArg: 0.913 ± 0.029
1.318MetSer: 1.318 ± 0.035
1.124MetThr: 1.124 ± 0.029
1.578MetVal: 1.578 ± 0.038
0.168MetTrp: 0.168 ± 0.012
0.658MetTyr: 0.658 ± 0.021
0.0MetXaa: 0.0 ± 0.0
Asn
3.441AsnAla: 3.441 ± 0.056
0.427AsnCys: 0.427 ± 0.026
2.902AsnAsp: 2.902 ± 0.058
3.55AsnGlu: 3.55 ± 0.051
2.874AsnPhe: 2.874 ± 0.059
4.154AsnGly: 4.154 ± 0.1
1.135AsnHis: 1.135 ± 0.031
4.028AsnIle: 4.028 ± 0.062
3.32AsnLys: 3.32 ± 0.058
5.284AsnLeu: 5.284 ± 0.075
1.197AsnMet: 1.197 ± 0.028
2.962AsnAsn: 2.962 ± 0.061
2.904AsnPro: 2.904 ± 0.052
2.274AsnGln: 2.274 ± 0.041
2.489AsnArg: 2.489 ± 0.053
3.65AsnSer: 3.65 ± 0.059
3.49AsnThr: 3.49 ± 0.073
3.361AsnVal: 3.361 ± 0.064
0.702AsnTrp: 0.702 ± 0.026
2.339AsnTyr: 2.339 ± 0.043
0.0AsnXaa: 0.0 ± 0.0
Pro
1.85ProAla: 1.85 ± 0.041
0.209ProCys: 0.209 ± 0.013
2.178ProAsp: 2.178 ± 0.052
3.012ProGlu: 3.012 ± 0.053
2.094ProPhe: 2.094 ± 0.039
2.112ProGly: 2.112 ± 0.049
0.633ProHis: 0.633 ± 0.023
2.731ProIle: 2.731 ± 0.046
2.739ProLys: 2.739 ± 0.047
3.277ProLeu: 3.277 ± 0.056
0.82ProMet: 0.82 ± 0.027
2.408ProAsn: 2.408 ± 0.055
1.018ProPro: 1.018 ± 0.031
1.126ProGln: 1.126 ± 0.026
1.094ProArg: 1.094 ± 0.035
2.383ProSer: 2.383 ± 0.05
1.979ProThr: 1.979 ± 0.053
2.325ProVal: 2.325 ± 0.045
0.387ProTrp: 0.387 ± 0.017
1.397ProTyr: 1.397 ± 0.039
0.0ProXaa: 0.0 ± 0.0
Gln
1.905GlnAla: 1.905 ± 0.039
0.183GlnCys: 0.183 ± 0.012
1.822GlnAsp: 1.822 ± 0.038
2.547GlnGlu: 2.547 ± 0.046
1.768GlnPhe: 1.768 ± 0.039
2.024GlnGly: 2.024 ± 0.037
0.636GlnHis: 0.636 ± 0.022
2.652GlnIle: 2.652 ± 0.046
2.801GlnLys: 2.801 ± 0.051
3.688GlnLeu: 3.688 ± 0.058
0.921GlnMet: 0.921 ± 0.027
2.212GlnAsn: 2.212 ± 0.04
1.118GlnPro: 1.118 ± 0.033
1.433GlnGln: 1.433 ± 0.038
1.515GlnArg: 1.515 ± 0.035
1.977GlnSer: 1.977 ± 0.035
1.807GlnThr: 1.807 ± 0.036
2.14GlnVal: 2.14 ± 0.035
0.427GlnTrp: 0.427 ± 0.019
1.27GlnTyr: 1.27 ± 0.031
0.0GlnXaa: 0.0 ± 0.0
Arg
2.238ArgAla: 2.238 ± 0.051
0.206ArgCys: 0.206 ± 0.013
2.025ArgAsp: 2.025 ± 0.041
2.614ArgGlu: 2.614 ± 0.051
2.335ArgPhe: 2.335 ± 0.048
2.182ArgGly: 2.182 ± 0.045
0.653ArgHis: 0.653 ± 0.025
3.248ArgIle: 3.248 ± 0.055
3.096ArgLys: 3.096 ± 0.052
3.872ArgLeu: 3.872 ± 0.063
0.988ArgMet: 0.988 ± 0.028
2.316ArgAsn: 2.316 ± 0.044
1.372ArgPro: 1.372 ± 0.033
1.299ArgGln: 1.299 ± 0.03
1.658ArgArg: 1.658 ± 0.042
2.152ArgSer: 2.152 ± 0.043
2.062ArgThr: 2.062 ± 0.039
2.365ArgVal: 2.365 ± 0.04
0.48ArgTrp: 0.48 ± 0.02
1.746ArgTyr: 1.746 ± 0.037
0.0ArgXaa: 0.0 ± 0.0
Ser
3.728SerAla: 3.728 ± 0.054
0.61SerCys: 0.61 ± 0.026
3.596SerAsp: 3.596 ± 0.06
4.321SerGlu: 4.321 ± 0.062
4.034SerPhe: 4.034 ± 0.064
4.667SerGly: 4.667 ± 0.086
1.098SerHis: 1.098 ± 0.027
5.197SerIle: 5.197 ± 0.059
4.738SerLys: 4.738 ± 0.069
6.419SerLeu: 6.419 ± 0.077
1.423SerMet: 1.423 ± 0.036
3.622SerAsn: 3.622 ± 0.061
2.272SerPro: 2.272 ± 0.041
2.279SerGln: 2.279 ± 0.041
2.436SerArg: 2.436 ± 0.039
4.265SerSer: 4.265 ± 0.06
3.487SerThr: 3.487 ± 0.065
4.023SerVal: 4.023 ± 0.06
0.752SerTrp: 0.752 ± 0.024
2.621SerTyr: 2.621 ± 0.047
0.0SerXaa: 0.0 ± 0.0
Thr
3.525ThrAla: 3.525 ± 0.079
0.351ThrCys: 0.351 ± 0.019
3.172ThrAsp: 3.172 ± 0.068
3.362ThrGlu: 3.362 ± 0.049
3.041ThrPhe: 3.041 ± 0.056
3.928ThrGly: 3.928 ± 0.079
1.01ThrHis: 1.01 ± 0.028
4.385ThrIle: 4.385 ± 0.071
3.386ThrLys: 3.386 ± 0.053
5.588ThrLeu: 5.588 ± 0.072
1.041ThrMet: 1.041 ± 0.033
3.03ThrAsn: 3.03 ± 0.072
2.409ThrPro: 2.409 ± 0.057
1.911ThrGln: 1.911 ± 0.035
1.787ThrArg: 1.787 ± 0.037
3.751ThrSer: 3.751 ± 0.058
3.185ThrThr: 3.185 ± 0.068
3.861ThrVal: 3.861 ± 0.085
0.642ThrTrp: 0.642 ± 0.027
2.207ThrTyr: 2.207 ± 0.05
0.0ThrXaa: 0.0 ± 0.0
Val
4.294ValAla: 4.294 ± 0.059
0.51ValCys: 0.51 ± 0.018
3.864ValAsp: 3.864 ± 0.055
4.242ValGlu: 4.242 ± 0.06
3.704ValPhe: 3.704 ± 0.051
4.114ValGly: 4.114 ± 0.059
1.153ValHis: 1.153 ± 0.032
4.341ValIle: 4.341 ± 0.063
3.985ValLys: 3.985 ± 0.071
6.576ValLeu: 6.576 ± 0.078
1.349ValMet: 1.349 ± 0.034
3.356ValAsn: 3.356 ± 0.06
2.398ValPro: 2.398 ± 0.044
2.044ValGln: 2.044 ± 0.04
2.303ValArg: 2.303 ± 0.049
4.615ValSer: 4.615 ± 0.067
3.512ValThr: 3.512 ± 0.093
4.526ValVal: 4.526 ± 0.067
0.665ValTrp: 0.665 ± 0.026
2.25ValTyr: 2.25 ± 0.049
0.0ValXaa: 0.0 ± 0.0
Trp
0.66TrpAla: 0.66 ± 0.022
0.098TrpCys: 0.098 ± 0.008
0.704TrpAsp: 0.704 ± 0.026
0.814TrpGlu: 0.814 ± 0.028
0.612TrpPhe: 0.612 ± 0.02
0.756TrpGly: 0.756 ± 0.026
0.241TrpHis: 0.241 ± 0.014
0.775TrpIle: 0.775 ± 0.028
0.849TrpLys: 0.849 ± 0.032
1.046TrpLeu: 1.046 ± 0.032
0.349TrpMet: 0.349 ± 0.02
0.668TrpAsn: 0.668 ± 0.02
0.288TrpPro: 0.288 ± 0.014
0.43TrpGln: 0.43 ± 0.018
0.498TrpArg: 0.498 ± 0.022
0.706TrpSer: 0.706 ± 0.023
0.618TrpThr: 0.618 ± 0.025
0.735TrpVal: 0.735 ± 0.025
0.183TrpTrp: 0.183 ± 0.013
0.457TrpTyr: 0.457 ± 0.019
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.376TyrAla: 2.376 ± 0.045
0.308TyrCys: 0.308 ± 0.016
2.185TyrAsp: 2.185 ± 0.044
2.465TyrGlu: 2.465 ± 0.051
2.328TyrPhe: 2.328 ± 0.045
2.619TyrGly: 2.619 ± 0.047
0.872TyrHis: 0.872 ± 0.028
2.319TyrIle: 2.319 ± 0.043
2.404TyrLys: 2.404 ± 0.046
3.814TyrLeu: 3.814 ± 0.059
0.69TyrMet: 0.69 ± 0.024
2.148TyrAsn: 2.148 ± 0.045
1.486TyrPro: 1.486 ± 0.035
1.609TyrGln: 1.609 ± 0.036
1.827TyrArg: 1.827 ± 0.042
2.462TyrSer: 2.462 ± 0.051
2.139TyrThr: 2.139 ± 0.043
2.275TyrVal: 2.275 ± 0.041
0.498TyrTrp: 0.498 ± 0.02
1.617TyrTyr: 1.617 ± 0.037
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4085 proteins (1342224 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski