Amino acid dipepetide frequency for Apis mellifera associated microvirus 51

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.217AlaAla: 2.217 ± 0.511
0.0AlaCys: 0.0 ± 0.0
3.695AlaAsp: 3.695 ± 1.346
5.913AlaGlu: 5.913 ± 2.041
1.478AlaPhe: 1.478 ± 1.04
5.174AlaGly: 5.174 ± 2.421
0.0AlaHis: 0.0 ± 0.0
2.217AlaIle: 2.217 ± 1.065
3.695AlaLys: 3.695 ± 1.253
5.913AlaLeu: 5.913 ± 1.129
1.478AlaMet: 1.478 ± 0.544
6.652AlaAsn: 6.652 ± 2.45
2.956AlaPro: 2.956 ± 1.213
6.652AlaGln: 6.652 ± 3.696
8.13AlaArg: 8.13 ± 2.073
5.913AlaSer: 5.913 ± 2.269
2.217AlaThr: 2.217 ± 1.158
1.478AlaVal: 1.478 ± 0.585
0.0AlaTrp: 0.0 ± 0.0
1.478AlaTyr: 1.478 ± 0.544
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.739CysAsp: 0.739 ± 0.52
1.478CysGlu: 1.478 ± 1.197
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.739CysIle: 0.739 ± 0.598
2.217CysLys: 2.217 ± 1.795
1.478CysLeu: 1.478 ± 1.197
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.478CysArg: 1.478 ± 0.889
0.739CysSer: 0.739 ± 0.598
0.739CysThr: 0.739 ± 0.598
0.739CysVal: 0.739 ± 0.771
0.739CysTrp: 0.739 ± 0.52
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.217AspAla: 2.217 ± 1.146
0.0AspCys: 0.0 ± 0.0
4.435AspAsp: 4.435 ± 2.246
2.217AspGlu: 2.217 ± 0.862
2.956AspPhe: 2.956 ± 0.9
5.913AspGly: 5.913 ± 1.807
0.739AspHis: 0.739 ± 0.829
1.478AspIle: 1.478 ± 1.34
0.739AspLys: 0.739 ± 0.598
4.435AspLeu: 4.435 ± 1.056
0.739AspMet: 0.739 ± 0.52
1.478AspAsn: 1.478 ± 0.837
3.695AspPro: 3.695 ± 0.988
0.739AspGln: 0.739 ± 0.52
3.695AspArg: 3.695 ± 1.349
2.956AspSer: 2.956 ± 1.757
3.695AspThr: 3.695 ± 1.403
2.956AspVal: 2.956 ± 1.208
1.478AspTrp: 1.478 ± 0.544
3.695AspTyr: 3.695 ± 1.346
0.0AspXaa: 0.0 ± 0.0
Glu
5.913GluAla: 5.913 ± 2.972
0.0GluCys: 0.0 ± 0.0
5.913GluAsp: 5.913 ± 1.547
6.652GluGlu: 6.652 ± 2.561
2.217GluPhe: 2.217 ± 0.879
4.435GluGly: 4.435 ± 1.364
1.478GluHis: 1.478 ± 0.862
2.217GluIle: 2.217 ± 0.879
3.695GluLys: 3.695 ± 1.701
4.435GluLeu: 4.435 ± 1.365
0.739GluMet: 0.739 ± 0.829
2.217GluAsn: 2.217 ± 1.242
0.739GluPro: 0.739 ± 0.829
2.217GluGln: 2.217 ± 1.425
0.739GluArg: 0.739 ± 0.67
5.913GluSer: 5.913 ± 2.51
4.435GluThr: 4.435 ± 1.631
5.174GluVal: 5.174 ± 2.23
1.478GluTrp: 1.478 ± 0.585
2.956GluTyr: 2.956 ± 1.339
0.0GluXaa: 0.0 ± 0.0
Phe
4.435PheAla: 4.435 ± 0.607
0.0PheCys: 0.0 ± 0.0
2.217PheAsp: 2.217 ± 1.609
2.217PheGlu: 2.217 ± 1.073
1.478PhePhe: 1.478 ± 1.04
2.956PheGly: 2.956 ± 1.015
0.0PheHis: 0.0 ± 0.0
1.478PheIle: 1.478 ± 0.585
0.739PheLys: 0.739 ± 0.598
0.739PheLeu: 0.739 ± 0.598
0.739PheMet: 0.739 ± 0.571
1.478PheAsn: 1.478 ± 0.766
1.478PhePro: 1.478 ± 0.544
2.217PheGln: 2.217 ± 0.511
5.174PheArg: 5.174 ± 1.206
5.913PheSer: 5.913 ± 2.232
2.956PheThr: 2.956 ± 1.087
1.478PheVal: 1.478 ± 0.544
2.217PheTrp: 2.217 ± 2.01
1.478PheTyr: 1.478 ± 0.766
0.0PheXaa: 0.0 ± 0.0
Gly
5.174GlyAla: 5.174 ± 1.287
1.478GlyCys: 1.478 ± 1.197
4.435GlyAsp: 4.435 ± 0.804
3.695GlyGlu: 3.695 ± 1.179
3.695GlyPhe: 3.695 ± 1.311
6.652GlyGly: 6.652 ± 1.877
2.217GlyHis: 2.217 ± 1.609
6.652GlyIle: 6.652 ± 1.541
5.913GlyLys: 5.913 ± 1.459
7.391GlyLeu: 7.391 ± 2.571
1.478GlyMet: 1.478 ± 0.544
3.695GlyAsn: 3.695 ± 1.349
3.695GlyPro: 3.695 ± 0.52
3.695GlyGln: 3.695 ± 1.895
2.956GlyArg: 2.956 ± 1.403
3.695GlySer: 3.695 ± 1.831
3.695GlyThr: 3.695 ± 1.808
5.174GlyVal: 5.174 ± 1.386
1.478GlyTrp: 1.478 ± 0.585
4.435GlyTyr: 4.435 ± 0.986
0.0GlyXaa: 0.0 ± 0.0
His
2.217HisAla: 2.217 ± 0.511
0.0HisCys: 0.0 ± 0.0
0.739HisAsp: 0.739 ± 0.771
2.217HisGlu: 2.217 ± 1.748
0.739HisPhe: 0.739 ± 0.829
1.478HisGly: 1.478 ± 1.04
0.739HisHis: 0.739 ± 0.52
2.956HisIle: 2.956 ± 0.994
0.0HisLys: 0.0 ± 0.0
0.0HisLeu: 0.0 ± 0.0
0.739HisMet: 0.739 ± 0.52
0.0HisAsn: 0.0 ± 0.0
2.956HisPro: 2.956 ± 0.668
0.739HisGln: 0.739 ± 0.829
1.478HisArg: 1.478 ± 0.889
2.956HisSer: 2.956 ± 0.946
0.0HisThr: 0.0 ± 0.0
1.478HisVal: 1.478 ± 1.04
0.739HisTrp: 0.739 ± 0.52
1.478HisTyr: 1.478 ± 0.544
0.0HisXaa: 0.0 ± 0.0
Ile
2.217IleAla: 2.217 ± 0.831
0.739IleCys: 0.739 ± 0.598
0.739IleAsp: 0.739 ± 0.52
0.739IleGlu: 0.739 ± 0.598
1.478IlePhe: 1.478 ± 1.04
5.913IleGly: 5.913 ± 1.143
0.739IleHis: 0.739 ± 0.52
0.739IleIle: 0.739 ± 0.52
3.695IleLys: 3.695 ± 1.499
2.956IleLeu: 2.956 ± 2.394
0.739IleMet: 0.739 ± 0.52
2.217IleAsn: 2.217 ± 0.879
3.695IlePro: 3.695 ± 0.815
5.174IleGln: 5.174 ± 1.59
5.174IleArg: 5.174 ± 0.695
4.435IleSer: 4.435 ± 1.491
2.217IleThr: 2.217 ± 0.881
1.478IleVal: 1.478 ± 0.585
0.739IleTrp: 0.739 ± 0.52
1.478IleTyr: 1.478 ± 0.544
0.0IleXaa: 0.0 ± 0.0
Lys
6.652LysAla: 6.652 ± 1.813
1.478LysCys: 1.478 ± 1.197
1.478LysAsp: 1.478 ± 0.544
6.652LysGlu: 6.652 ± 2.1
1.478LysPhe: 1.478 ± 0.544
5.913LysGly: 5.913 ± 1.819
0.739LysHis: 0.739 ± 0.598
5.913LysIle: 5.913 ± 1.685
5.174LysLys: 5.174 ± 3.398
4.435LysLeu: 4.435 ± 1.273
0.739LysMet: 0.739 ± 0.598
0.739LysAsn: 0.739 ± 0.67
3.695LysPro: 3.695 ± 0.871
1.478LysGln: 1.478 ± 0.585
3.695LysArg: 3.695 ± 1.179
1.478LysSer: 1.478 ± 0.585
2.217LysThr: 2.217 ± 0.671
1.478LysVal: 1.478 ± 1.34
0.739LysTrp: 0.739 ± 0.829
1.478LysTyr: 1.478 ± 1.036
0.0LysXaa: 0.0 ± 0.0
Leu
5.913LeuAla: 5.913 ± 2.769
0.739LeuCys: 0.739 ± 0.598
4.435LeuAsp: 4.435 ± 1.577
2.956LeuGlu: 2.956 ± 1.56
2.956LeuPhe: 2.956 ± 1.677
5.913LeuGly: 5.913 ± 1.474
2.217LeuHis: 2.217 ± 1.305
2.956LeuIle: 2.956 ± 0.946
2.956LeuLys: 2.956 ± 1.015
5.174LeuLeu: 5.174 ± 1.287
0.739LeuMet: 0.739 ± 0.538
4.435LeuAsn: 4.435 ± 1.702
5.913LeuPro: 5.913 ± 1.008
5.174LeuGln: 5.174 ± 2.815
8.13LeuArg: 8.13 ± 2.233
3.695LeuSer: 3.695 ± 1.213
3.695LeuThr: 3.695 ± 1.367
5.174LeuVal: 5.174 ± 1.717
1.478LeuTrp: 1.478 ± 0.544
0.739LeuTyr: 0.739 ± 0.67
0.0LeuXaa: 0.0 ± 0.0
Met
2.217MetAla: 2.217 ± 1.56
0.739MetCys: 0.739 ± 0.598
0.0MetAsp: 0.0 ± 0.0
1.478MetGlu: 1.478 ± 0.544
0.0MetPhe: 0.0 ± 0.0
2.217MetGly: 2.217 ± 1.146
0.739MetHis: 0.739 ± 0.52
1.478MetIle: 1.478 ± 1.01
0.739MetLys: 0.739 ± 0.52
1.478MetLeu: 1.478 ± 1.34
0.0MetMet: 0.0 ± 0.0
1.478MetAsn: 1.478 ± 0.544
0.739MetPro: 0.739 ± 0.598
1.478MetGln: 1.478 ± 0.837
0.739MetArg: 0.739 ± 0.52
2.956MetSer: 2.956 ± 1.559
0.0MetThr: 0.0 ± 0.0
1.478MetVal: 1.478 ± 0.585
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.956AsnAla: 2.956 ± 1.575
0.0AsnCys: 0.0 ± 0.0
4.435AsnAsp: 4.435 ± 0.888
1.478AsnGlu: 1.478 ± 0.544
3.695AsnPhe: 3.695 ± 2.196
2.956AsnGly: 2.956 ± 0.946
2.956AsnHis: 2.956 ± 1.087
1.478AsnIle: 1.478 ± 0.544
2.217AsnLys: 2.217 ± 0.767
2.217AsnLeu: 2.217 ± 0.831
1.478AsnMet: 1.478 ± 1.34
1.478AsnAsn: 1.478 ± 0.585
2.956AsnPro: 2.956 ± 1.482
4.435AsnGln: 4.435 ± 1.339
2.956AsnArg: 2.956 ± 1.579
1.478AsnSer: 1.478 ± 1.036
0.0AsnThr: 0.0 ± 0.0
2.956AsnVal: 2.956 ± 1.087
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.956ProAla: 2.956 ± 1.3
1.478ProCys: 1.478 ± 1.197
1.478ProAsp: 1.478 ± 0.585
5.913ProGlu: 5.913 ± 0.817
2.217ProPhe: 2.217 ± 0.879
7.391ProGly: 7.391 ± 2.316
1.478ProHis: 1.478 ± 0.837
2.217ProIle: 2.217 ± 0.879
3.695ProLys: 3.695 ± 1.441
6.652ProLeu: 6.652 ± 2.603
2.956ProMet: 2.956 ± 1.673
3.695ProAsn: 3.695 ± 1.002
3.695ProPro: 3.695 ± 1.653
0.0ProGln: 0.0 ± 0.0
1.478ProArg: 1.478 ± 0.766
2.217ProSer: 2.217 ± 1.274
3.695ProThr: 3.695 ± 1.253
5.174ProVal: 5.174 ± 1.402
0.739ProTrp: 0.739 ± 0.52
1.478ProTyr: 1.478 ± 1.01
0.0ProXaa: 0.0 ± 0.0
Gln
1.478GlnAla: 1.478 ± 1.04
1.478GlnCys: 1.478 ± 1.197
2.956GlnAsp: 2.956 ± 1.324
2.956GlnGlu: 2.956 ± 1.154
1.478GlnPhe: 1.478 ± 0.585
5.174GlnGly: 5.174 ± 1.746
0.739GlnHis: 0.739 ± 0.52
2.956GlnIle: 2.956 ± 2.174
3.695GlnLys: 3.695 ± 0.815
3.695GlnLeu: 3.695 ± 3.35
1.478GlnMet: 1.478 ± 0.837
2.217GlnAsn: 2.217 ± 0.862
1.478GlnPro: 1.478 ± 1.34
2.217GlnGln: 2.217 ± 1.158
6.652GlnArg: 6.652 ± 1.985
0.739GlnSer: 0.739 ± 0.52
6.652GlnThr: 6.652 ± 1.877
0.739GlnVal: 0.739 ± 0.829
1.478GlnTrp: 1.478 ± 1.036
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.695ArgAla: 3.695 ± 1.692
0.0ArgCys: 0.0 ± 0.0
2.217ArgAsp: 2.217 ± 0.831
2.956ArgGlu: 2.956 ± 0.668
5.174ArgPhe: 5.174 ± 1.329
1.478ArgGly: 1.478 ± 0.766
1.478ArgHis: 1.478 ± 1.171
3.695ArgIle: 3.695 ± 1.18
4.435ArgLys: 4.435 ± 2.195
5.913ArgLeu: 5.913 ± 2.323
2.217ArgMet: 2.217 ± 0.636
3.695ArgAsn: 3.695 ± 1.77
7.391ArgPro: 7.391 ± 1.538
2.956ArgGln: 2.956 ± 1.778
14.043ArgArg: 14.043 ± 7.05
6.652ArgSer: 6.652 ± 3.097
3.695ArgThr: 3.695 ± 0.921
5.174ArgVal: 5.174 ± 2.039
0.0ArgTrp: 0.0 ± 0.0
6.652ArgTyr: 6.652 ± 2.554
0.0ArgXaa: 0.0 ± 0.0
Ser
5.913SerAla: 5.913 ± 2.485
0.739SerCys: 0.739 ± 0.771
2.217SerAsp: 2.217 ± 1.018
4.435SerGlu: 4.435 ± 0.804
3.695SerPhe: 3.695 ± 1.77
6.652SerGly: 6.652 ± 0.866
0.739SerHis: 0.739 ± 0.52
2.217SerIle: 2.217 ± 1.56
3.695SerLys: 3.695 ± 1.441
5.913SerLeu: 5.913 ± 1.768
1.478SerMet: 1.478 ± 0.544
2.217SerAsn: 2.217 ± 0.767
4.435SerPro: 4.435 ± 1.194
4.435SerGln: 4.435 ± 2.769
8.869SerArg: 8.869 ± 4.834
8.869SerSer: 8.869 ± 2.608
2.217SerThr: 2.217 ± 0.831
2.217SerVal: 2.217 ± 1.56
0.0SerTrp: 0.0 ± 0.0
0.739SerTyr: 0.739 ± 0.52
0.0SerXaa: 0.0 ± 0.0
Thr
2.956ThrAla: 2.956 ± 0.602
0.739ThrCys: 0.739 ± 0.52
3.695ThrAsp: 3.695 ± 1.002
2.956ThrGlu: 2.956 ± 1.575
2.217ThrPhe: 2.217 ± 0.879
5.174ThrGly: 5.174 ± 2.136
2.217ThrHis: 2.217 ± 1.078
3.695ThrIle: 3.695 ± 2.039
3.695ThrLys: 3.695 ± 0.52
3.695ThrLeu: 3.695 ± 1.367
0.739ThrMet: 0.739 ± 0.764
2.217ThrAsn: 2.217 ± 0.881
2.217ThrPro: 2.217 ± 1.425
2.217ThrGln: 2.217 ± 0.511
1.478ThrArg: 1.478 ± 1.34
2.956ThrSer: 2.956 ± 1.087
5.174ThrThr: 5.174 ± 2.815
1.478ThrVal: 1.478 ± 0.837
2.217ThrTrp: 2.217 ± 1.018
1.478ThrTyr: 1.478 ± 0.544
0.0ThrXaa: 0.0 ± 0.0
Val
2.956ValAla: 2.956 ± 0.602
1.478ValCys: 1.478 ± 0.766
0.739ValAsp: 0.739 ± 0.52
2.217ValGlu: 2.217 ± 0.767
2.956ValPhe: 2.956 ± 0.807
2.956ValGly: 2.956 ± 0.994
2.217ValHis: 2.217 ± 0.881
1.478ValIle: 1.478 ± 1.197
4.435ValLys: 4.435 ± 1.662
4.435ValLeu: 4.435 ± 1.837
0.739ValMet: 0.739 ± 0.52
1.478ValAsn: 1.478 ± 0.585
6.652ValPro: 6.652 ± 1.984
1.478ValGln: 1.478 ± 0.585
1.478ValArg: 1.478 ± 0.766
5.174ValSer: 5.174 ± 1.287
3.695ValThr: 3.695 ± 1.525
1.478ValVal: 1.478 ± 0.766
0.739ValTrp: 0.739 ± 0.598
1.478ValTyr: 1.478 ± 1.04
0.0ValXaa: 0.0 ± 0.0
Trp
0.739TrpAla: 0.739 ± 0.52
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.217TrpGlu: 2.217 ± 1.56
0.739TrpPhe: 0.739 ± 0.67
1.478TrpGly: 1.478 ± 1.197
1.478TrpHis: 1.478 ± 0.766
0.739TrpIle: 0.739 ± 0.52
1.478TrpLys: 1.478 ± 0.837
0.739TrpLeu: 0.739 ± 0.598
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.956TrpArg: 2.956 ± 2.012
1.478TrpSer: 1.478 ± 0.585
1.478TrpThr: 1.478 ± 0.544
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.478TrpTyr: 1.478 ± 1.04
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.435TyrAla: 4.435 ± 1.206
0.0TyrCys: 0.0 ± 0.0
3.695TyrAsp: 3.695 ± 1.045
2.217TyrGlu: 2.217 ± 1.158
1.478TyrPhe: 1.478 ± 0.544
1.478TyrGly: 1.478 ± 0.544
0.739TyrHis: 0.739 ± 0.598
0.0TyrIle: 0.0 ± 0.0
0.739TyrLys: 0.739 ± 0.52
3.695TyrLeu: 3.695 ± 1.831
0.0TyrMet: 0.0 ± 0.0
0.739TyrAsn: 0.739 ± 0.52
2.217TyrPro: 2.217 ± 0.881
2.956TyrGln: 2.956 ± 1.579
2.217TyrArg: 2.217 ± 1.56
1.478TyrSer: 1.478 ± 0.766
0.739TyrThr: 0.739 ± 0.52
2.956TyrVal: 2.956 ± 1.087
0.739TyrTrp: 0.739 ± 0.52
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1354 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski