Amino acid dipepetide frequency for South African cassava mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.028AlaAla: 6.028 ± 1.376
1.808AlaCys: 1.808 ± 0.643
1.206AlaAsp: 1.206 ± 0.912
0.603AlaGlu: 0.603 ± 0.684
0.603AlaPhe: 0.603 ± 0.555
0.603AlaGly: 0.603 ± 0.498
1.206AlaHis: 1.206 ± 0.836
1.808AlaIle: 1.808 ± 0.933
4.822AlaLys: 4.822 ± 1.134
6.631AlaLeu: 6.631 ± 1.88
0.0AlaMet: 0.0 ± 0.0
0.603AlaAsn: 0.603 ± 0.498
2.411AlaPro: 2.411 ± 1.138
3.617AlaGln: 3.617 ± 2.022
4.219AlaArg: 4.219 ± 1.304
6.631AlaSer: 6.631 ± 2.422
4.219AlaThr: 4.219 ± 1.812
1.808AlaVal: 1.808 ± 1.21
1.206AlaTrp: 1.206 ± 0.997
0.603AlaTyr: 0.603 ± 0.498
0.0AlaXaa: 0.0 ± 0.0
Cys
0.603CysAla: 0.603 ± 0.612
1.206CysCys: 1.206 ± 1.368
0.603CysAsp: 0.603 ± 0.5
0.603CysGlu: 0.603 ± 0.553
0.603CysPhe: 0.603 ± 0.589
1.206CysGly: 1.206 ± 0.642
0.0CysHis: 0.0 ± 0.0
1.808CysIle: 1.808 ± 0.883
0.603CysLys: 0.603 ± 0.553
1.206CysLeu: 1.206 ± 0.666
1.808CysMet: 1.808 ± 0.95
1.206CysAsn: 1.206 ± 0.611
1.206CysPro: 1.206 ± 1.368
0.0CysGln: 0.0 ± 0.0
1.808CysArg: 1.808 ± 1.064
1.206CysSer: 1.206 ± 1.224
1.808CysThr: 1.808 ± 0.964
0.603CysVal: 0.603 ± 0.553
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.219AspAla: 4.219 ± 1.944
1.206AspCys: 1.206 ± 0.777
3.617AspAsp: 3.617 ± 0.714
1.808AspGlu: 1.808 ± 0.617
1.808AspPhe: 1.808 ± 0.584
1.206AspGly: 1.206 ± 0.997
2.411AspHis: 2.411 ± 1.13
3.014AspIle: 3.014 ± 1.231
1.808AspLys: 1.808 ± 0.786
7.233AspLeu: 7.233 ± 1.89
0.603AspMet: 0.603 ± 0.452
4.219AspAsn: 4.219 ± 1.542
2.411AspPro: 2.411 ± 1.078
0.603AspGln: 0.603 ± 0.498
1.808AspArg: 1.808 ± 1.05
5.425AspSer: 5.425 ± 1.878
1.206AspThr: 1.206 ± 0.642
5.425AspVal: 5.425 ± 1.483
1.808AspTrp: 1.808 ± 0.973
1.206AspTyr: 1.206 ± 0.796
0.0AspXaa: 0.0 ± 0.0
Glu
2.411GluAla: 2.411 ± 1.14
0.603GluCys: 0.603 ± 0.612
3.014GluAsp: 3.014 ± 1.215
1.808GluGlu: 1.808 ± 1.194
2.411GluPhe: 2.411 ± 1.628
4.822GluGly: 4.822 ± 0.864
1.206GluHis: 1.206 ± 0.777
1.206GluIle: 1.206 ± 0.791
1.206GluLys: 1.206 ± 0.611
4.219GluLeu: 4.219 ± 1.597
0.0GluMet: 0.0 ± 0.0
3.617GluAsn: 3.617 ± 1.493
4.219GluPro: 4.219 ± 1.175
2.411GluGln: 2.411 ± 1.198
0.603GluArg: 0.603 ± 0.5
2.411GluSer: 2.411 ± 1.085
3.014GluThr: 3.014 ± 1.615
0.0GluVal: 0.0 ± 0.0
0.603GluTrp: 0.603 ± 0.612
2.411GluTyr: 2.411 ± 1.637
0.0GluXaa: 0.0 ± 0.0
Phe
1.206PheAla: 1.206 ± 0.611
0.603PheCys: 0.603 ± 0.553
2.411PheAsp: 2.411 ± 1.111
1.206PheGlu: 1.206 ± 0.611
2.411PhePhe: 2.411 ± 0.966
1.206PheGly: 1.206 ± 0.612
2.411PheHis: 2.411 ± 1.14
1.206PheIle: 1.206 ± 0.997
3.617PheLys: 3.617 ± 1.059
4.822PheLeu: 4.822 ± 1.847
1.206PheMet: 1.206 ± 0.664
3.014PheAsn: 3.014 ± 1.231
1.808PhePro: 1.808 ± 1.138
1.206PheGln: 1.206 ± 0.997
4.219PheArg: 4.219 ± 1.92
5.425PheSer: 5.425 ± 1.063
2.411PheThr: 2.411 ± 1.138
1.808PheVal: 1.808 ± 1.064
0.603PheTrp: 0.603 ± 0.555
1.808PheTyr: 1.808 ± 1.361
0.0PheXaa: 0.0 ± 0.0
Gly
3.617GlyAla: 3.617 ± 1.449
1.206GlyCys: 1.206 ± 0.839
3.617GlyAsp: 3.617 ± 1.163
4.219GlyGlu: 4.219 ± 1.325
1.808GlyPhe: 1.808 ± 0.902
4.219GlyGly: 4.219 ± 1.934
1.206GlyHis: 1.206 ± 0.836
3.617GlyIle: 3.617 ± 1.05
4.219GlyLys: 4.219 ± 1.509
2.411GlyLeu: 2.411 ± 0.977
1.808GlyMet: 1.808 ± 0.907
3.617GlyAsn: 3.617 ± 1.341
3.014GlyPro: 3.014 ± 1.055
1.808GlyGln: 1.808 ± 0.878
2.411GlyArg: 2.411 ± 0.978
2.411GlySer: 2.411 ± 1.356
2.411GlyThr: 2.411 ± 1.159
3.014GlyVal: 3.014 ± 1.317
0.0GlyTrp: 0.0 ± 0.0
1.206GlyTyr: 1.206 ± 0.666
0.0GlyXaa: 0.0 ± 0.0
His
2.411HisAla: 2.411 ± 1.111
1.808HisCys: 1.808 ± 1.367
1.808HisAsp: 1.808 ± 1.325
1.808HisGlu: 1.808 ± 0.973
2.411HisPhe: 2.411 ± 1.08
1.206HisGly: 1.206 ± 0.891
2.411HisHis: 2.411 ± 2.447
3.014HisIle: 3.014 ± 1.201
1.206HisLys: 1.206 ± 0.875
1.206HisLeu: 1.206 ± 0.997
0.0HisMet: 0.0 ± 0.0
2.411HisAsn: 2.411 ± 1.094
1.808HisPro: 1.808 ± 0.677
2.411HisGln: 2.411 ± 1.222
4.219HisArg: 4.219 ± 1.234
1.206HisSer: 1.206 ± 0.758
2.411HisThr: 2.411 ± 1.612
2.411HisVal: 2.411 ± 0.945
0.0HisTrp: 0.0 ± 0.0
1.206HisTyr: 1.206 ± 0.611
0.0HisXaa: 0.0 ± 0.0
Ile
0.603IleAla: 0.603 ± 0.555
1.206IleCys: 1.206 ± 0.722
3.014IleAsp: 3.014 ± 1.136
2.411IleGlu: 2.411 ± 1.039
1.808IlePhe: 1.808 ± 1.062
3.014IleGly: 3.014 ± 1.019
1.808IleHis: 1.808 ± 0.837
3.014IleIle: 3.014 ± 1.422
6.631IleLys: 6.631 ± 0.666
1.808IleLeu: 1.808 ± 1.039
1.808IleMet: 1.808 ± 0.877
4.822IleAsn: 4.822 ± 2.094
1.206IlePro: 1.206 ± 0.997
3.617IleGln: 3.617 ± 1.951
4.219IleArg: 4.219 ± 1.326
4.219IleSer: 4.219 ± 1.01
5.425IleThr: 5.425 ± 2.266
2.411IleVal: 2.411 ± 0.753
1.808IleTrp: 1.808 ± 0.899
1.206IleTyr: 1.206 ± 1.106
0.0IleXaa: 0.0 ± 0.0
Lys
4.219LysAla: 4.219 ± 1.802
1.808LysCys: 1.808 ± 0.763
3.014LysAsp: 3.014 ± 1.184
3.617LysGlu: 3.617 ± 1.284
1.808LysPhe: 1.808 ± 0.851
3.014LysGly: 3.014 ± 1.524
1.808LysHis: 1.808 ± 0.584
3.014LysIle: 3.014 ± 1.163
1.206LysLys: 1.206 ± 0.612
4.219LysLeu: 4.219 ± 1.992
0.603LysMet: 0.603 ± 0.629
4.219LysAsn: 4.219 ± 1.457
3.617LysPro: 3.617 ± 0.807
2.411LysGln: 2.411 ± 1.113
3.014LysArg: 3.014 ± 1.661
4.822LysSer: 4.822 ± 1.168
3.014LysThr: 3.014 ± 1.31
3.014LysVal: 3.014 ± 1.184
0.0LysTrp: 0.0 ± 0.0
4.219LysTyr: 4.219 ± 1.34
0.0LysXaa: 0.0 ± 0.0
Leu
1.808LeuAla: 1.808 ± 1.04
1.808LeuCys: 1.808 ± 1.062
5.425LeuAsp: 5.425 ± 2.308
4.822LeuGlu: 4.822 ± 1.615
3.014LeuPhe: 3.014 ± 1.051
3.617LeuGly: 3.617 ± 0.805
4.219LeuHis: 4.219 ± 1.694
3.014LeuIle: 3.014 ± 1.311
5.425LeuLys: 5.425 ± 1.057
6.028LeuLeu: 6.028 ± 2.149
1.206LeuMet: 1.206 ± 0.696
7.233LeuAsn: 7.233 ± 1.67
2.411LeuPro: 2.411 ± 1.055
4.219LeuGln: 4.219 ± 1.302
6.028LeuArg: 6.028 ± 1.619
4.219LeuSer: 4.219 ± 1.602
3.617LeuThr: 3.617 ± 1.791
3.617LeuVal: 3.617 ± 1.574
0.0LeuTrp: 0.0 ± 0.0
4.219LeuTyr: 4.219 ± 1.839
0.0LeuXaa: 0.0 ± 0.0
Met
1.206MetAla: 1.206 ± 0.612
0.0MetCys: 0.0 ± 0.0
3.617MetAsp: 3.617 ± 1.383
0.0MetGlu: 0.0 ± 0.0
1.808MetPhe: 1.808 ± 1.66
2.411MetGly: 2.411 ± 1.089
0.0MetHis: 0.0 ± 0.0
0.603MetIle: 0.603 ± 0.589
1.808MetLys: 1.808 ± 0.899
0.603MetLeu: 0.603 ± 0.684
0.603MetMet: 0.603 ± 0.572
0.603MetAsn: 0.603 ± 0.589
1.808MetPro: 1.808 ± 0.788
0.603MetGln: 0.603 ± 0.612
2.411MetArg: 2.411 ± 1.034
0.603MetSer: 0.603 ± 0.553
0.603MetThr: 0.603 ± 0.629
0.0MetVal: 0.0 ± 0.0
1.206MetTrp: 1.206 ± 0.836
2.411MetTyr: 2.411 ± 0.998
0.0MetXaa: 0.0 ± 0.0
Asn
3.014AsnAla: 3.014 ± 0.747
0.603AsnCys: 0.603 ± 0.498
3.617AsnAsp: 3.617 ± 1.024
1.808AsnGlu: 1.808 ± 0.835
1.206AsnPhe: 1.206 ± 0.774
3.014AsnGly: 3.014 ± 1.137
5.425AsnHis: 5.425 ± 2.783
3.014AsnIle: 3.014 ± 0.577
3.014AsnLys: 3.014 ± 0.589
3.617AsnLeu: 3.617 ± 0.911
3.014AsnMet: 3.014 ± 1.455
2.411AsnAsn: 2.411 ± 1.076
3.617AsnPro: 3.617 ± 1.283
2.411AsnGln: 2.411 ± 0.848
0.603AsnArg: 0.603 ± 0.555
2.411AsnSer: 2.411 ± 0.487
2.411AsnThr: 2.411 ± 1.329
5.425AsnVal: 5.425 ± 1.785
0.0AsnTrp: 0.0 ± 0.0
3.014AsnTyr: 3.014 ± 1.215
0.0AsnXaa: 0.0 ± 0.0
Pro
1.808ProAla: 1.808 ± 0.815
1.808ProCys: 1.808 ± 0.835
1.808ProAsp: 1.808 ± 0.883
1.808ProGlu: 1.808 ± 0.898
3.014ProPhe: 3.014 ± 0.796
3.617ProGly: 3.617 ± 1.523
3.014ProHis: 3.014 ± 2.09
6.028ProIle: 6.028 ± 1.565
3.014ProLys: 3.014 ± 1.625
3.014ProLeu: 3.014 ± 1.15
1.808ProMet: 1.808 ± 1.531
1.206ProAsn: 1.206 ± 0.836
3.014ProPro: 3.014 ± 0.838
1.206ProGln: 1.206 ± 0.822
6.028ProArg: 6.028 ± 1.438
6.631ProSer: 6.631 ± 1.782
6.631ProThr: 6.631 ± 2.082
2.411ProVal: 2.411 ± 1.527
1.206ProTrp: 1.206 ± 0.611
3.617ProTyr: 3.617 ± 1.237
0.0ProXaa: 0.0 ± 0.0
Gln
4.822GlnAla: 4.822 ± 1.811
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.808GlnGlu: 1.808 ± 0.746
3.014GlnPhe: 3.014 ± 1.184
2.411GlnGly: 2.411 ± 0.754
2.411GlnHis: 2.411 ± 1.471
2.411GlnIle: 2.411 ± 1.018
1.808GlnLys: 1.808 ± 0.791
3.014GlnLeu: 3.014 ± 1.136
0.0GlnMet: 0.0 ± 0.0
1.808GlnAsn: 1.808 ± 1.433
3.617GlnPro: 3.617 ± 2.149
3.014GlnGln: 3.014 ± 0.854
2.411GlnArg: 2.411 ± 1.1
4.219GlnSer: 4.219 ± 1.733
1.808GlnThr: 1.808 ± 0.788
5.425GlnVal: 5.425 ± 1.899
0.603GlnTrp: 0.603 ± 0.498
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.617ArgAla: 3.617 ± 1.218
1.808ArgCys: 1.808 ± 0.815
4.219ArgAsp: 4.219 ± 1.781
3.014ArgGlu: 3.014 ± 1.426
4.219ArgPhe: 4.219 ± 0.991
4.219ArgGly: 4.219 ± 1.519
2.411ArgHis: 2.411 ± 1.427
2.411ArgIle: 2.411 ± 0.959
3.617ArgLys: 3.617 ± 1.167
6.028ArgLeu: 6.028 ± 2.012
1.808ArgMet: 1.808 ± 1.106
0.603ArgAsn: 0.603 ± 0.555
4.822ArgPro: 4.822 ± 1.641
2.411ArgGln: 2.411 ± 0.811
9.042ArgArg: 9.042 ± 3.057
6.631ArgSer: 6.631 ± 1.47
4.219ArgThr: 4.219 ± 1.028
6.028ArgVal: 6.028 ± 1.909
0.0ArgTrp: 0.0 ± 0.0
1.808ArgTyr: 1.808 ± 0.835
0.0ArgXaa: 0.0 ± 0.0
Ser
2.411SerAla: 2.411 ± 1.413
0.0SerCys: 0.0 ± 0.0
3.014SerAsp: 3.014 ± 0.979
1.206SerGlu: 1.206 ± 0.611
4.219SerPhe: 4.219 ± 1.513
3.014SerGly: 3.014 ± 1.545
1.206SerHis: 1.206 ± 1.224
6.631SerIle: 6.631 ± 0.844
6.028SerLys: 6.028 ± 0.694
5.425SerLeu: 5.425 ± 2.454
0.603SerMet: 0.603 ± 0.555
3.617SerAsn: 3.617 ± 1.254
7.836SerPro: 7.836 ± 1.624
6.028SerGln: 6.028 ± 2.871
5.425SerArg: 5.425 ± 1.317
10.85SerSer: 10.85 ± 2.516
7.836SerThr: 7.836 ± 2.56
4.822SerVal: 4.822 ± 1.685
0.603SerTrp: 0.603 ± 0.553
3.617SerTyr: 3.617 ± 1.196
0.0SerXaa: 0.0 ± 0.0
Thr
3.014ThrAla: 3.014 ± 1.423
0.603ThrCys: 0.603 ± 0.5
3.014ThrAsp: 3.014 ± 1.566
3.617ThrGlu: 3.617 ± 1.028
3.014ThrPhe: 3.014 ± 0.609
3.617ThrGly: 3.617 ± 1.059
3.617ThrHis: 3.617 ± 1.017
3.617ThrIle: 3.617 ± 1.513
1.206ThrLys: 1.206 ± 0.611
5.425ThrLeu: 5.425 ± 1.741
1.808ThrMet: 1.808 ± 0.672
5.425ThrAsn: 5.425 ± 1.721
6.028ThrPro: 6.028 ± 1.336
0.603ThrGln: 0.603 ± 0.629
3.617ThrArg: 3.617 ± 1.192
4.822ThrSer: 4.822 ± 2.201
3.014ThrThr: 3.014 ± 1.534
3.617ThrVal: 3.617 ± 1.204
1.206ThrTrp: 1.206 ± 0.791
1.808ThrTyr: 1.808 ± 0.789
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
4.219ValAsp: 4.219 ± 1.476
2.411ValGlu: 2.411 ± 1.623
2.411ValPhe: 2.411 ± 1.377
2.411ValGly: 2.411 ± 1.224
0.603ValHis: 0.603 ± 0.684
4.822ValIle: 4.822 ± 1.413
3.014ValLys: 3.014 ± 1.129
4.822ValLeu: 4.822 ± 2.272
1.808ValMet: 1.808 ± 1.05
0.603ValAsn: 0.603 ± 0.5
6.028ValPro: 6.028 ± 1.468
4.219ValGln: 4.219 ± 2.523
3.617ValArg: 3.617 ± 2.135
6.631ValSer: 6.631 ± 2.541
3.014ValThr: 3.014 ± 1.072
1.206ValVal: 1.206 ± 1.106
1.206ValTrp: 1.206 ± 0.733
4.822ValTyr: 4.822 ± 2.291
0.0ValXaa: 0.0 ± 0.0
Trp
1.808TrpAla: 1.808 ± 0.968
0.0TrpCys: 0.0 ± 0.0
0.603TrpAsp: 0.603 ± 0.684
0.603TrpGlu: 0.603 ± 0.589
0.0TrpPhe: 0.0 ± 0.0
0.603TrpGly: 0.603 ± 0.498
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.603TrpMet: 0.603 ± 0.553
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.603TrpGln: 0.603 ± 0.498
1.808TrpArg: 1.808 ± 0.677
1.808TrpSer: 1.808 ± 0.861
1.808TrpThr: 1.808 ± 1.038
1.206TrpVal: 1.206 ± 0.664
0.0TrpTrp: 0.0 ± 0.0
0.603TrpTyr: 0.603 ± 0.498
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.808TyrAla: 1.808 ± 0.584
0.0TyrCys: 0.0 ± 0.0
1.206TyrAsp: 1.206 ± 0.774
3.014TyrGlu: 3.014 ± 1.294
3.014TyrPhe: 3.014 ± 1.027
2.411TyrGly: 2.411 ± 0.944
0.0TyrHis: 0.0 ± 0.0
1.808TyrIle: 1.808 ± 0.672
2.411TyrLys: 2.411 ± 1.014
4.219TyrLeu: 4.219 ± 1.632
1.206TyrMet: 1.206 ± 0.728
2.411TyrAsn: 2.411 ± 1.14
2.411TyrPro: 2.411 ± 0.675
1.206TyrGln: 1.206 ± 0.791
5.425TyrArg: 5.425 ± 1.992
1.808TyrSer: 1.808 ± 1.064
1.808TyrThr: 1.808 ± 1.039
3.617TyrVal: 3.617 ± 1.91
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1660 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski