Amino acid dipepetide frequency for Candidatus Defluviicoccus seviourii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.102AlaAla: 21.102 ± 0.217	1.562AlaCys: 1.562 ± 0.043	7.801AlaAsp: 7.801 ± 0.118	8.192AlaGlu: 8.192 ± 0.12	4.589AlaPhe: 4.589 ± 0.075	11.842AlaGly: 11.842 ± 0.12	2.485AlaHis: 2.485 ± 0.051	6.296AlaIle: 6.296 ± 0.084	3.514AlaLys: 3.514 ± 0.073	14.644AlaLeu: 14.644 ± 0.172	2.996AlaMet: 2.996 ± 0.058	2.768AlaAsn: 2.768 ± 0.047	6.167AlaPro: 6.167 ± 0.096	3.977AlaGln: 3.977 ± 0.079	9.806AlaArg: 9.806 ± 0.118	6.182AlaSer: 6.182 ± 0.08	6.391AlaThr: 6.391 ± 0.092	10.221AlaVal: 10.221 ± 0.11	1.773AlaTrp: 1.773 ± 0.044	2.505AlaTyr: 2.505 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.326CysAla: 1.326 ± 0.045	0.153CysCys: 0.153 ± 0.014	0.566CysAsp: 0.566 ± 0.025	0.584CysGlu: 0.584 ± 0.024	0.356CysPhe: 0.356 ± 0.021	1.124CysGly: 1.124 ± 0.039	0.296CysHis: 0.296 ± 0.02	0.431CysIle: 0.431 ± 0.023	0.213CysLys: 0.213 ± 0.014	0.947CysLeu: 0.947 ± 0.032	0.197CysMet: 0.197 ± 0.014	0.243CysAsn: 0.243 ± 0.018	0.61CysPro: 0.61 ± 0.033	0.336CysGln: 0.336 ± 0.018	0.953CysArg: 0.953 ± 0.031	0.551CysSer: 0.551 ± 0.024	0.516CysThr: 0.516 ± 0.025	0.731CysVal: 0.731 ± 0.03	0.138CysTrp: 0.138 ± 0.011	0.23CysTyr: 0.23 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	7.213AspAla: 7.213 ± 0.098	0.505AspCys: 0.505 ± 0.024	3.096AspAsp: 3.096 ± 0.072	3.291AspGlu: 3.291 ± 0.068	2.039AspPhe: 2.039 ± 0.043	5.09AspGly: 5.09 ± 0.088	1.179AspHis: 1.179 ± 0.038	2.535AspIle: 2.535 ± 0.053	1.295AspLys: 1.295 ± 0.039	5.685AspLeu: 5.685 ± 0.087	0.939AspMet: 0.939 ± 0.028	1.129AspAsn: 1.129 ± 0.035	3.463AspPro: 3.463 ± 0.065	1.769AspGln: 1.769 ± 0.044	4.412AspArg: 4.412 ± 0.068	2.261AspSer: 2.261 ± 0.057	2.456AspThr: 2.456 ± 0.079	4.296AspVal: 4.296 ± 0.069	0.873AspTrp: 0.873 ± 0.031	1.358AspTyr: 1.358 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	8.156GluAla: 8.156 ± 0.113	0.412GluCys: 0.412 ± 0.023	2.598GluAsp: 2.598 ± 0.062	3.172GluGlu: 3.172 ± 0.074	1.511GluPhe: 1.511 ± 0.045	4.32GluGly: 4.32 ± 0.064	1.28GluHis: 1.28 ± 0.038	3.131GluIle: 3.131 ± 0.065	1.785GluLys: 1.785 ± 0.051	5.138GluLeu: 5.138 ± 0.075	1.316GluMet: 1.316 ± 0.036	1.282GluAsn: 1.282 ± 0.036	3.038GluPro: 3.038 ± 0.066	2.223GluGln: 2.223 ± 0.048	5.815GluArg: 5.815 ± 0.088	2.315GluSer: 2.315 ± 0.039	3.411GluThr: 3.411 ± 0.053	3.884GluVal: 3.884 ± 0.07	0.64GluTrp: 0.64 ± 0.03	0.94GluTyr: 0.94 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.824PheAla: 4.824 ± 0.072	0.437PheCys: 0.437 ± 0.023	2.384PheAsp: 2.384 ± 0.046	2.09PheGlu: 2.09 ± 0.049	1.434PhePhe: 1.434 ± 0.041	3.445PheGly: 3.445 ± 0.069	0.691PheHis: 0.691 ± 0.025	1.51PheIle: 1.51 ± 0.037	0.865PheLys: 0.865 ± 0.026	3.529PheLeu: 3.529 ± 0.07	0.685PheMet: 0.685 ± 0.026	0.934PheAsn: 0.934 ± 0.036	1.486PhePro: 1.486 ± 0.036	0.958PheGln: 0.958 ± 0.031	2.428PheArg: 2.428 ± 0.042	1.899PheSer: 1.899 ± 0.048	1.862PheThr: 1.862 ± 0.045	2.833PheVal: 2.833 ± 0.058	0.465PheTrp: 0.465 ± 0.023	0.891PheTyr: 0.891 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	9.608GlyAla: 9.608 ± 0.119	1.091GlyCys: 1.091 ± 0.04	4.464GlyAsp: 4.464 ± 0.08	4.68GlyGlu: 4.68 ± 0.063	3.29GlyPhe: 3.29 ± 0.063	7.435GlyGly: 7.435 ± 0.122	1.859GlyHis: 1.859 ± 0.047	4.346GlyIle: 4.346 ± 0.069	2.585GlyLys: 2.585 ± 0.049	8.97GlyLeu: 8.97 ± 0.099	1.984GlyMet: 1.984 ± 0.046	2.068GlyAsn: 2.068 ± 0.062	3.56GlyPro: 3.56 ± 0.071	2.692GlyGln: 2.692 ± 0.056	6.987GlyArg: 6.987 ± 0.096	4.808GlySer: 4.808 ± 0.08	4.924GlyThr: 4.924 ± 0.077	6.064GlyVal: 6.064 ± 0.079	1.392GlyTrp: 1.392 ± 0.042	2.144GlyTyr: 2.144 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.631HisAla: 2.631 ± 0.054	0.264HisCys: 0.264 ± 0.016	1.13HisAsp: 1.13 ± 0.038	1.043HisGlu: 1.043 ± 0.031	0.823HisPhe: 0.823 ± 0.031	2.013HisGly: 2.013 ± 0.05	0.615HisHis: 0.615 ± 0.028	0.877HisIle: 0.877 ± 0.029	0.438HisLys: 0.438 ± 0.021	2.195HisLeu: 2.195 ± 0.051	0.409HisMet: 0.409 ± 0.021	0.482HisAsn: 0.482 ± 0.023	1.416HisPro: 1.416 ± 0.04	0.661HisGln: 0.661 ± 0.033	1.589HisArg: 1.589 ± 0.038	0.906HisSer: 0.906 ± 0.031	0.887HisThr: 0.887 ± 0.029	1.544HisVal: 1.544 ± 0.041	0.339HisTrp: 0.339 ± 0.021	0.542HisTyr: 0.542 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	7.077IleAla: 7.077 ± 0.089	0.521IleCys: 0.521 ± 0.024	3.516IleAsp: 3.516 ± 0.064	3.789IleGlu: 3.789 ± 0.063	1.39IlePhe: 1.39 ± 0.045	4.845IleGly: 4.845 ± 0.08	0.842IleHis: 0.842 ± 0.027	2.165IleIle: 2.165 ± 0.052	1.4IleLys: 1.4 ± 0.041	4.207IleLeu: 4.207 ± 0.069	0.721IleMet: 0.721 ± 0.028	1.373IleAsn: 1.373 ± 0.04	2.082IlePro: 2.082 ± 0.043	1.139IleGln: 1.139 ± 0.039	3.246IleArg: 3.246 ± 0.06	2.336IleSer: 2.336 ± 0.054	2.658IleThr: 2.658 ± 0.052	4.086IleVal: 4.086 ± 0.065	0.502IleTrp: 0.502 ± 0.02	0.971IleTyr: 0.971 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	3.623LysAla: 3.623 ± 0.069	0.179LysCys: 0.179 ± 0.013	1.424LysAsp: 1.424 ± 0.041	1.52LysGlu: 1.52 ± 0.049	0.71LysPhe: 0.71 ± 0.03	2.272LysGly: 2.272 ± 0.061	0.541LysHis: 0.541 ± 0.021	1.344LysIle: 1.344 ± 0.039	1.017LysLys: 1.017 ± 0.036	2.678LysLeu: 2.678 ± 0.06	0.638LysMet: 0.638 ± 0.024	0.694LysAsn: 0.694 ± 0.029	1.852LysPro: 1.852 ± 0.05	0.876LysGln: 0.876 ± 0.034	2.377LysArg: 2.377 ± 0.048	1.356LysSer: 1.356 ± 0.038	1.601LysThr: 1.601 ± 0.041	2.053LysVal: 2.053 ± 0.05	0.319LysTrp: 0.319 ± 0.019	0.583LysTyr: 0.583 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	15.332LeuAla: 15.332 ± 0.147	1.087LeuCys: 1.087 ± 0.035	5.926LeuAsp: 5.926 ± 0.09	5.177LeuGlu: 5.177 ± 0.074	3.724LeuPhe: 3.724 ± 0.073	8.412LeuGly: 8.412 ± 0.108	2.042LeuHis: 2.042 ± 0.048	5.338LeuIle: 5.338 ± 0.087	3.709LeuLys: 3.709 ± 0.06	9.963LeuLeu: 9.963 ± 0.149	2.174LeuMet: 2.174 ± 0.057	2.529LeuAsn: 2.529 ± 0.052	5.872LeuPro: 5.872 ± 0.077	3.008LeuGln: 3.008 ± 0.066	7.4LeuArg: 7.4 ± 0.087	6.031LeuSer: 6.031 ± 0.079	5.641LeuThr: 5.641 ± 0.081	7.77LeuVal: 7.77 ± 0.106	1.189LeuTrp: 1.189 ± 0.037	2.053LeuTyr: 2.053 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.877MetAla: 2.877 ± 0.051	0.164MetCys: 0.164 ± 0.013	0.86MetAsp: 0.86 ± 0.032	0.924MetGlu: 0.924 ± 0.031	0.625MetPhe: 0.625 ± 0.024	1.476MetGly: 1.476 ± 0.034	0.423MetHis: 0.423 ± 0.019	1.103MetIle: 1.103 ± 0.033	0.675MetLys: 0.675 ± 0.027	2.305MetLeu: 2.305 ± 0.055	0.581MetMet: 0.581 ± 0.025	0.565MetAsn: 0.565 ± 0.024	1.353MetPro: 1.353 ± 0.037	0.748MetGln: 0.748 ± 0.029	1.796MetArg: 1.796 ± 0.046	1.2MetSer: 1.2 ± 0.036	1.538MetThr: 1.538 ± 0.041	1.563MetVal: 1.563 ± 0.042	0.188MetTrp: 0.188 ± 0.014	0.283MetTyr: 0.283 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.934AsnAla: 2.934 ± 0.046	0.246AsnCys: 0.246 ± 0.015	1.392AsnAsp: 1.392 ± 0.065	1.171AsnGlu: 1.171 ± 0.037	0.776AsnPhe: 0.776 ± 0.028	2.016AsnGly: 2.016 ± 0.056	0.508AsnHis: 0.508 ± 0.023	1.14AsnIle: 1.14 ± 0.035	0.602AsnLys: 0.602 ± 0.026	2.377AsnLeu: 2.377 ± 0.054	0.447AsnMet: 0.447 ± 0.022	0.61AsnAsn: 0.61 ± 0.028	1.593AsnPro: 1.593 ± 0.041	0.676AsnGln: 0.676 ± 0.029	1.85AsnArg: 1.85 ± 0.053	0.993AsnSer: 0.993 ± 0.03	1.19AsnThr: 1.19 ± 0.037	1.797AsnVal: 1.797 ± 0.042	0.312AsnTrp: 0.312 ± 0.02	0.528AsnTyr: 0.528 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	7.732ProAla: 7.732 ± 0.117	0.474ProCys: 0.474 ± 0.023	3.211ProAsp: 3.211 ± 0.065	3.513ProGlu: 3.513 ± 0.067	2.114ProPhe: 2.114 ± 0.049	4.432ProGly: 4.432 ± 0.073	1.124ProHis: 1.124 ± 0.035	2.254ProIle: 2.254 ± 0.048	1.459ProLys: 1.459 ± 0.037	5.375ProLeu: 5.375 ± 0.078	1.133ProMet: 1.133 ± 0.033	1.119ProAsn: 1.119 ± 0.041	3.38ProPro: 3.38 ± 0.076	1.82ProGln: 1.82 ± 0.052	3.343ProArg: 3.343 ± 0.056	2.856ProSer: 2.856 ± 0.049	2.521ProThr: 2.521 ± 0.047	4.314ProVal: 4.314 ± 0.073	0.792ProTrp: 0.792 ± 0.032	1.101ProTyr: 1.101 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.622GlnAla: 4.622 ± 0.074	0.239GlnCys: 0.239 ± 0.016	1.319GlnAsp: 1.319 ± 0.035	1.602GlnGlu: 1.602 ± 0.042	0.954GlnPhe: 0.954 ± 0.03	2.421GlnGly: 2.421 ± 0.048	0.737GlnHis: 0.737 ± 0.026	1.633GlnIle: 1.633 ± 0.042	0.853GlnLys: 0.853 ± 0.029	2.937GlnLeu: 2.937 ± 0.055	0.803GlnMet: 0.803 ± 0.03	0.709GlnAsn: 0.709 ± 0.026	2.215GlnPro: 2.215 ± 0.049	1.272GlnGln: 1.272 ± 0.042	2.802GlnArg: 2.802 ± 0.054	1.491GlnSer: 1.491 ± 0.038	1.616GlnThr: 1.616 ± 0.037	2.415GlnVal: 2.415 ± 0.051	0.386GlnTrp: 0.386 ± 0.022	0.571GlnTyr: 0.571 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	9.105ArgAla: 9.105 ± 0.109	0.81ArgCys: 0.81 ± 0.028	3.9ArgAsp: 3.9 ± 0.068	4.212ArgGlu: 4.212 ± 0.067	3.193ArgPhe: 3.193 ± 0.063	5.289ArgGly: 5.289 ± 0.076	1.885ArgHis: 1.885 ± 0.042	4.068ArgIle: 4.068 ± 0.063	1.993ArgLys: 1.993 ± 0.05	9.652ArgLeu: 9.652 ± 0.104	1.823ArgMet: 1.823 ± 0.043	1.767ArgAsn: 1.767 ± 0.043	4.227ArgPro: 4.227 ± 0.076	2.972ArgGln: 2.972 ± 0.06	6.972ArgArg: 6.972 ± 0.113	3.946ArgSer: 3.946 ± 0.066	3.801ArgThr: 3.801 ± 0.065	5.383ArgVal: 5.383 ± 0.077	1.178ArgTrp: 1.178 ± 0.035	1.887ArgTyr: 1.887 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	6.269SerAla: 6.269 ± 0.085	0.506SerCys: 0.506 ± 0.02	2.635SerAsp: 2.635 ± 0.051	2.696SerGlu: 2.696 ± 0.053	1.979SerPhe: 1.979 ± 0.048	5.17SerGly: 5.17 ± 0.08	0.999SerHis: 0.999 ± 0.033	2.303SerIle: 2.303 ± 0.048	1.188SerLys: 1.188 ± 0.036	5.357SerLeu: 5.357 ± 0.085	1.138SerMet: 1.138 ± 0.033	1.095SerAsn: 1.095 ± 0.03	2.601SerPro: 2.601 ± 0.046	1.487SerGln: 1.487 ± 0.04	3.743SerArg: 3.743 ± 0.067	2.567SerSer: 2.567 ± 0.063	2.451SerThr: 2.451 ± 0.054	3.94SerVal: 3.94 ± 0.059	0.686SerTrp: 0.686 ± 0.028	1.195SerTyr: 1.195 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	6.912ThrAla: 6.912 ± 0.088	0.487ThrCys: 0.487 ± 0.026	2.731ThrAsp: 2.731 ± 0.063	2.664ThrGlu: 2.664 ± 0.052	1.941ThrPhe: 1.941 ± 0.049	4.741ThrGly: 4.741 ± 0.072	0.987ThrHis: 0.987 ± 0.03	2.729ThrIle: 2.729 ± 0.053	1.298ThrLys: 1.298 ± 0.041	6.02ThrLeu: 6.02 ± 0.087	0.996ThrMet: 0.996 ± 0.034	1.122ThrAsn: 1.122 ± 0.039	3.161ThrPro: 3.161 ± 0.062	1.378ThrGln: 1.378 ± 0.038	3.393ThrArg: 3.393 ± 0.058	2.512ThrSer: 2.512 ± 0.055	2.831ThrThr: 2.831 ± 0.064	4.362ThrVal: 4.362 ± 0.076	0.704ThrTrp: 0.704 ± 0.028	1.174ThrTyr: 1.174 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	9.866ValAla: 9.866 ± 0.098	0.883ValCys: 0.883 ± 0.031	4.053ValAsp: 4.053 ± 0.068	4.333ValGlu: 4.333 ± 0.06	2.874ValPhe: 2.874 ± 0.059	5.686ValGly: 5.686 ± 0.086	1.442ValHis: 1.442 ± 0.038	4.221ValIle: 4.221 ± 0.07	1.917ValLys: 1.917 ± 0.046	8.259ValLeu: 8.259 ± 0.096	1.607ValMet: 1.607 ± 0.041	1.827ValAsn: 1.827 ± 0.047	4.134ValPro: 4.134 ± 0.053	2.153ValGln: 2.153 ± 0.045	5.845ValArg: 5.845 ± 0.083	4.062ValSer: 4.062 ± 0.067	4.072ValThr: 4.072 ± 0.065	6.483ValVal: 6.483 ± 0.097	0.914ValTrp: 0.914 ± 0.034	1.496ValTyr: 1.496 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.17TrpAla: 1.17 ± 0.038	0.174TrpCys: 0.174 ± 0.015	0.581TrpAsp: 0.581 ± 0.026	0.577TrpGlu: 0.577 ± 0.028	0.489TrpPhe: 0.489 ± 0.022	0.91TrpGly: 0.91 ± 0.035	0.376TrpHis: 0.376 ± 0.018	0.621TrpIle: 0.621 ± 0.025	0.351TrpLys: 0.351 ± 0.02	1.849TrpLeu: 1.849 ± 0.051	0.316TrpMet: 0.316 ± 0.02	0.339TrpAsn: 0.339 ± 0.019	0.762TrpPro: 0.762 ± 0.03	0.722TrpGln: 0.722 ± 0.028	1.36TrpArg: 1.36 ± 0.041	0.76TrpSer: 0.76 ± 0.029	0.674TrpThr: 0.674 ± 0.029	0.818TrpVal: 0.818 ± 0.033	0.24TrpTrp: 0.24 ± 0.017	0.308TrpTyr: 0.308 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.433TyrAla: 2.433 ± 0.052	0.302TyrCys: 0.302 ± 0.018	1.299TyrAsp: 1.299 ± 0.037	1.136TyrGlu: 1.136 ± 0.039	0.839TyrPhe: 0.839 ± 0.028	2.013TyrGly: 2.013 ± 0.05	0.492TyrHis: 0.492 ± 0.023	0.82TyrIle: 0.82 ± 0.024	0.498TyrLys: 0.498 ± 0.024	2.289TyrLeu: 2.289 ± 0.057	0.345TyrMet: 0.345 ± 0.018	0.503TyrAsn: 0.503 ± 0.025	1.098TyrPro: 1.098 ± 0.032	0.729TyrGln: 0.729 ± 0.029	1.952TyrArg: 1.952 ± 0.037	0.975TyrSer: 0.975 ± 0.033	1.102TyrThr: 1.102 ± 0.037	1.566TyrVal: 1.566 ± 0.041	0.366TyrTrp: 0.366 ± 0.018	0.569TyrTyr: 0.569 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3221 proteins (997156 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---