Amino acid dipepetide frequency for Sphingobacterium gobiense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.512AlaAla: 5.512 ± 0.085	0.658AlaCys: 0.658 ± 0.021	4.315AlaAsp: 4.315 ± 0.059	4.59AlaGlu: 4.59 ± 0.056	3.438AlaPhe: 3.438 ± 0.044	5.03AlaGly: 5.03 ± 0.067	1.358AlaHis: 1.358 ± 0.033	5.366AlaIle: 5.366 ± 0.065	4.268AlaLys: 4.268 ± 0.066	6.852AlaLeu: 6.852 ± 0.08	1.673AlaMet: 1.673 ± 0.038	3.588AlaAsn: 3.588 ± 0.053	2.173AlaPro: 2.173 ± 0.044	2.826AlaGln: 2.826 ± 0.047	2.9AlaArg: 2.9 ± 0.048	4.599AlaSer: 4.599 ± 0.059	3.874AlaThr: 3.874 ± 0.065	4.872AlaVal: 4.872 ± 0.065	0.907AlaTrp: 0.907 ± 0.026	3.182AlaTyr: 3.182 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.516CysAla: 0.516 ± 0.022	0.117CysCys: 0.117 ± 0.011	0.364CysAsp: 0.364 ± 0.017	0.39CysGlu: 0.39 ± 0.018	0.377CysPhe: 0.377 ± 0.017	0.553CysGly: 0.553 ± 0.021	0.177CysHis: 0.177 ± 0.013	0.542CysIle: 0.542 ± 0.019	0.368CysLys: 0.368 ± 0.018	0.708CysLeu: 0.708 ± 0.022	0.171CysMet: 0.171 ± 0.01	0.31CysAsn: 0.31 ± 0.016	0.276CysPro: 0.276 ± 0.015	0.241CysGln: 0.241 ± 0.014	0.309CysArg: 0.309 ± 0.017	0.527CysSer: 0.527 ± 0.022	0.391CysThr: 0.391 ± 0.016	0.455CysVal: 0.455 ± 0.019	0.08CysTrp: 0.08 ± 0.008	0.317CysTyr: 0.317 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	4.035AspAla: 4.035 ± 0.054	0.326AspCys: 0.326 ± 0.016	2.893AspAsp: 2.893 ± 0.053	3.733AspGlu: 3.733 ± 0.055	3.245AspPhe: 3.245 ± 0.058	4.298AspGly: 4.298 ± 0.064	1.048AspHis: 1.048 ± 0.027	4.495AspIle: 4.495 ± 0.059	3.615AspLys: 3.615 ± 0.051	5.099AspLeu: 5.099 ± 0.067	1.394AspMet: 1.394 ± 0.032	2.934AspAsn: 2.934 ± 0.046	2.158AspPro: 2.158 ± 0.038	1.816AspGln: 1.816 ± 0.035	2.745AspArg: 2.745 ± 0.047	2.896AspSer: 2.896 ± 0.057	2.766AspThr: 2.766 ± 0.048	3.848AspVal: 3.848 ± 0.056	0.9AspTrp: 0.9 ± 0.026	2.765AspTyr: 2.765 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	4.542GluAla: 4.542 ± 0.061	0.308GluCys: 0.308 ± 0.014	3.292GluAsp: 3.292 ± 0.045	4.843GluGlu: 4.843 ± 0.077	2.321GluPhe: 2.321 ± 0.045	3.99GluGly: 3.99 ± 0.055	1.332GluHis: 1.332 ± 0.033	4.705GluIle: 4.705 ± 0.06	4.767GluLys: 4.767 ± 0.067	5.815GluLeu: 5.815 ± 0.077	1.573GluMet: 1.573 ± 0.036	3.607GluAsn: 3.607 ± 0.05	1.748GluPro: 1.748 ± 0.031	2.858GluGln: 2.858 ± 0.049	3.386GluArg: 3.386 ± 0.055	3.195GluSer: 3.195 ± 0.043	3.335GluThr: 3.335 ± 0.054	4.177GluVal: 4.177 ± 0.06	0.773GluTrp: 0.773 ± 0.027	2.175GluTyr: 2.175 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.247PheAla: 3.247 ± 0.055	0.435PheCys: 0.435 ± 0.018	3.019PheAsp: 3.019 ± 0.056	2.846PheGlu: 2.846 ± 0.049	2.442PhePhe: 2.442 ± 0.053	3.53PheGly: 3.53 ± 0.06	0.986PheHis: 0.986 ± 0.029	3.216PheIle: 3.216 ± 0.049	2.606PheLys: 2.606 ± 0.045	4.345PheLeu: 4.345 ± 0.058	1.168PheMet: 1.168 ± 0.032	2.577PheAsn: 2.577 ± 0.048	1.845PhePro: 1.845 ± 0.041	1.634PheGln: 1.634 ± 0.037	2.185PheArg: 2.185 ± 0.041	3.49PheSer: 3.49 ± 0.052	2.717PheThr: 2.717 ± 0.046	3.062PheVal: 3.062 ± 0.045	0.633PheTrp: 0.633 ± 0.021	2.055PheTyr: 2.055 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	4.788GlyAla: 4.788 ± 0.062	0.545GlyCys: 0.545 ± 0.021	3.693GlyAsp: 3.693 ± 0.059	4.038GlyGlu: 4.038 ± 0.053	3.461GlyPhe: 3.461 ± 0.057	4.982GlyGly: 4.982 ± 0.08	1.299GlyHis: 1.299 ± 0.034	5.27GlyIle: 5.27 ± 0.07	4.742GlyLys: 4.742 ± 0.063	6.249GlyLeu: 6.249 ± 0.079	1.776GlyMet: 1.776 ± 0.043	3.758GlyAsn: 3.758 ± 0.06	1.529GlyPro: 1.529 ± 0.038	2.367GlyGln: 2.367 ± 0.048	3.178GlyArg: 3.178 ± 0.063	4.256GlySer: 4.256 ± 0.058	4.141GlyThr: 4.141 ± 0.064	4.816GlyVal: 4.816 ± 0.066	0.98GlyTrp: 0.98 ± 0.025	3.421GlyTyr: 3.421 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.452HisAla: 1.452 ± 0.029	0.167HisCys: 0.167 ± 0.011	1.037HisAsp: 1.037 ± 0.028	1.05HisGlu: 1.05 ± 0.029	1.162HisPhe: 1.162 ± 0.028	1.304HisGly: 1.304 ± 0.03	0.579HisHis: 0.579 ± 0.025	1.676HisIle: 1.676 ± 0.04	1.027HisLys: 1.027 ± 0.026	1.939HisLeu: 1.939 ± 0.04	0.377HisMet: 0.377 ± 0.017	1.03HisAsn: 1.03 ± 0.027	1.026HisPro: 1.026 ± 0.028	0.739HisGln: 0.739 ± 0.022	1.03HisArg: 1.03 ± 0.026	1.014HisSer: 1.014 ± 0.031	1.187HisThr: 1.187 ± 0.029	1.279HisVal: 1.279 ± 0.035	0.286HisTrp: 0.286 ± 0.015	0.992HisTyr: 0.992 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.651IleAla: 5.651 ± 0.074	0.61IleCys: 0.61 ± 0.023	4.488IleAsp: 4.488 ± 0.057	4.4IleGlu: 4.4 ± 0.068	2.994IlePhe: 2.994 ± 0.051	5.037IleGly: 5.037 ± 0.072	1.458IleHis: 1.458 ± 0.034	4.583IleIle: 4.583 ± 0.075	4.137IleLys: 4.137 ± 0.059	6.271IleLeu: 6.271 ± 0.074	1.404IleMet: 1.404 ± 0.032	3.654IleAsn: 3.654 ± 0.058	3.147IlePro: 3.147 ± 0.047	2.631IleGln: 2.631 ± 0.049	3.394IleArg: 3.394 ± 0.053	4.706IleSer: 4.706 ± 0.063	3.983IleThr: 3.983 ± 0.052	4.532IleVal: 4.532 ± 0.069	0.824IleTrp: 0.824 ± 0.028	2.624IleTyr: 2.624 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.376LysAla: 4.376 ± 0.066	0.25LysCys: 0.25 ± 0.013	3.642LysAsp: 3.642 ± 0.054	4.743LysGlu: 4.743 ± 0.075	2.222LysPhe: 2.222 ± 0.041	3.979LysGly: 3.979 ± 0.056	1.279LysHis: 1.279 ± 0.028	4.405LysIle: 4.405 ± 0.071	4.615LysLys: 4.615 ± 0.069	5.374LysLeu: 5.374 ± 0.063	1.645LysMet: 1.645 ± 0.037	3.553LysAsn: 3.553 ± 0.054	2.309LysPro: 2.309 ± 0.042	2.482LysGln: 2.482 ± 0.046	3.059LysArg: 3.059 ± 0.048	3.48LysSer: 3.48 ± 0.052	3.522LysThr: 3.522 ± 0.055	3.932LysVal: 3.932 ± 0.051	0.76LysTrp: 0.76 ± 0.02	2.443LysTyr: 2.443 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	6.807LeuAla: 6.807 ± 0.084	0.781LeuCys: 0.781 ± 0.027	5.254LeuAsp: 5.254 ± 0.067	5.423LeuGlu: 5.423 ± 0.078	4.633LeuPhe: 4.633 ± 0.061	6.147LeuGly: 6.147 ± 0.071	1.941LeuHis: 1.941 ± 0.038	6.078LeuIle: 6.078 ± 0.08	5.84LeuLys: 5.84 ± 0.069	9.248LeuLeu: 9.248 ± 0.105	2.176LeuMet: 2.176 ± 0.038	4.879LeuAsn: 4.879 ± 0.063	3.997LeuPro: 3.997 ± 0.053	3.724LeuGln: 3.724 ± 0.056	4.348LeuArg: 4.348 ± 0.051	6.698LeuSer: 6.698 ± 0.083	5.26LeuThr: 5.26 ± 0.065	5.584LeuVal: 5.584 ± 0.066	1.045LeuTrp: 1.045 ± 0.028	3.66LeuTyr: 3.66 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	1.828MetAla: 1.828 ± 0.038	0.142MetCys: 0.142 ± 0.01	1.371MetAsp: 1.371 ± 0.03	1.568MetGlu: 1.568 ± 0.036	0.868MetPhe: 0.868 ± 0.025	1.639MetGly: 1.639 ± 0.036	0.481MetHis: 0.481 ± 0.02	1.416MetIle: 1.416 ± 0.038	1.753MetLys: 1.753 ± 0.033	2.207MetLeu: 2.207 ± 0.043	0.664MetMet: 0.664 ± 0.024	1.26MetAsn: 1.26 ± 0.028	0.97MetPro: 0.97 ± 0.031	0.995MetGln: 0.995 ± 0.027	1.168MetArg: 1.168 ± 0.028	1.355MetSer: 1.355 ± 0.032	1.195MetThr: 1.195 ± 0.032	1.485MetVal: 1.485 ± 0.031	0.224MetTrp: 0.224 ± 0.012	0.744MetTyr: 0.744 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.67AsnAla: 3.67 ± 0.061	0.299AsnCys: 0.299 ± 0.017	2.712AsnAsp: 2.712 ± 0.051	3.028AsnGlu: 3.028 ± 0.046	2.495AsnPhe: 2.495 ± 0.046	3.861AsnGly: 3.861 ± 0.066	1.002AsnHis: 1.002 ± 0.029	3.965AsnIle: 3.965 ± 0.065	3.237AsnLys: 3.237 ± 0.051	4.809AsnLeu: 4.809 ± 0.063	1.297AsnMet: 1.297 ± 0.029	2.978AsnAsn: 2.978 ± 0.05	2.661AsnPro: 2.661 ± 0.045	1.968AsnGln: 1.968 ± 0.04	2.724AsnArg: 2.724 ± 0.049	2.909AsnSer: 2.909 ± 0.052	3.09AsnThr: 3.09 ± 0.05	3.306AsnVal: 3.306 ± 0.05	0.774AsnTrp: 0.774 ± 0.025	2.394AsnTyr: 2.394 ± 0.046	0.0AsnXaa: 0.0 ± 0.0
Pro	2.636ProAla: 2.636 ± 0.05	0.228ProCys: 0.228 ± 0.012	2.492ProAsp: 2.492 ± 0.04	2.852ProGlu: 2.852 ± 0.049	1.942ProPhe: 1.942 ± 0.033	2.43ProGly: 2.43 ± 0.045	0.812ProHis: 0.812 ± 0.027	2.62ProIle: 2.62 ± 0.049	2.081ProLys: 2.081 ± 0.04	3.367ProLeu: 3.367 ± 0.045	0.762ProMet: 0.762 ± 0.024	2.056ProAsn: 2.056 ± 0.043	0.936ProPro: 0.936 ± 0.029	1.388ProGln: 1.388 ± 0.036	1.436ProArg: 1.436 ± 0.035	2.304ProSer: 2.304 ± 0.037	2.178ProThr: 2.178 ± 0.042	2.6ProVal: 2.6 ± 0.046	0.493ProTrp: 0.493 ± 0.021	1.621ProTyr: 1.621 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	2.698GlnAla: 2.698 ± 0.042	0.176GlnCys: 0.176 ± 0.011	1.963GlnAsp: 1.963 ± 0.04	2.595GlnGlu: 2.595 ± 0.047	1.64GlnPhe: 1.64 ± 0.034	2.344GlnGly: 2.344 ± 0.042	0.995GlnHis: 0.995 ± 0.028	2.556GlnIle: 2.556 ± 0.053	2.303GlnLys: 2.303 ± 0.041	3.854GlnLeu: 3.854 ± 0.06	0.872GlnMet: 0.872 ± 0.026	1.948GlnAsn: 1.948 ± 0.039	1.363GlnPro: 1.363 ± 0.033	2.153GlnGln: 2.153 ± 0.051	1.901GlnArg: 1.901 ± 0.038	1.987GlnSer: 1.987 ± 0.037	2.186GlnThr: 2.186 ± 0.04	2.423GlnVal: 2.423 ± 0.042	0.485GlnTrp: 0.485 ± 0.02	1.69GlnTyr: 1.69 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.997ArgAla: 2.997 ± 0.045	0.256ArgCys: 0.256 ± 0.014	2.537ArgAsp: 2.537 ± 0.037	2.96ArgGlu: 2.96 ± 0.052	2.52ArgPhe: 2.52 ± 0.046	2.712ArgGly: 2.712 ± 0.053	0.928ArgHis: 0.928 ± 0.025	3.418ArgIle: 3.418 ± 0.049	3.007ArgLys: 3.007 ± 0.053	4.448ArgLeu: 4.448 ± 0.061	1.232ArgMet: 1.232 ± 0.029	2.714ArgAsn: 2.714 ± 0.049	1.612ArgPro: 1.612 ± 0.038	1.769ArgGln: 1.769 ± 0.036	2.194ArgArg: 2.194 ± 0.046	2.658ArgSer: 2.658 ± 0.052	2.588ArgThr: 2.588 ± 0.046	2.927ArgVal: 2.927 ± 0.045	0.754ArgTrp: 0.754 ± 0.027	2.482ArgTyr: 2.482 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	4.314SerAla: 4.314 ± 0.057	0.598SerCys: 0.598 ± 0.022	3.267SerAsp: 3.267 ± 0.047	3.283SerGlu: 3.283 ± 0.054	3.443SerPhe: 3.443 ± 0.05	4.623SerGly: 4.623 ± 0.061	1.14SerHis: 1.14 ± 0.029	4.4SerIle: 4.4 ± 0.058	3.422SerLys: 3.422 ± 0.055	6.05SerLeu: 6.05 ± 0.068	1.335SerMet: 1.335 ± 0.03	3.022SerAsn: 3.022 ± 0.052	2.388SerPro: 2.388 ± 0.042	1.936SerGln: 1.936 ± 0.039	2.716SerArg: 2.716 ± 0.047	4.124SerSer: 4.124 ± 0.061	3.611SerThr: 3.611 ± 0.051	4.104SerVal: 4.104 ± 0.057	0.807SerTrp: 0.807 ± 0.026	2.793SerTyr: 2.793 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	4.276ThrAla: 4.276 ± 0.06	0.326ThrCys: 0.326 ± 0.016	3.406ThrAsp: 3.406 ± 0.054	3.201ThrGlu: 3.201 ± 0.051	2.78ThrPhe: 2.78 ± 0.053	4.324ThrGly: 4.324 ± 0.064	1.086ThrHis: 1.086 ± 0.031	4.037ThrIle: 4.037 ± 0.061	3.116ThrLys: 3.116 ± 0.047	5.425ThrLeu: 5.425 ± 0.066	1.062ThrMet: 1.062 ± 0.029	2.68ThrAsn: 2.68 ± 0.048	2.478ThrPro: 2.478 ± 0.04	1.901ThrGln: 1.901 ± 0.038	2.112ThrArg: 2.112 ± 0.039	3.478ThrSer: 3.478 ± 0.058	3.227ThrThr: 3.227 ± 0.055	4.017ThrVal: 4.017 ± 0.048	0.687ThrTrp: 0.687 ± 0.025	2.445ThrTyr: 2.445 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	4.674ValAla: 4.674 ± 0.064	0.541ValCys: 0.541 ± 0.021	4.025ValAsp: 4.025 ± 0.06	3.978ValGlu: 3.978 ± 0.054	3.188ValPhe: 3.188 ± 0.057	4.389ValGly: 4.389 ± 0.058	1.216ValHis: 1.216 ± 0.036	4.338ValIle: 4.338 ± 0.051	3.865ValLys: 3.865 ± 0.059	6.339ValLeu: 6.339 ± 0.069	1.441ValMet: 1.441 ± 0.037	3.397ValAsn: 3.397 ± 0.057	2.523ValPro: 2.523 ± 0.045	2.362ValGln: 2.362 ± 0.042	2.954ValArg: 2.954 ± 0.053	4.44ValSer: 4.44 ± 0.063	3.47ValThr: 3.47 ± 0.056	4.725ValVal: 4.725 ± 0.066	0.772ValTrp: 0.772 ± 0.023	2.673ValTyr: 2.673 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.85TrpAla: 0.85 ± 0.026	0.115TrpCys: 0.115 ± 0.01	0.739TrpAsp: 0.739 ± 0.024	0.863TrpGlu: 0.863 ± 0.025	0.566TrpPhe: 0.566 ± 0.019	0.985TrpGly: 0.985 ± 0.03	0.278TrpHis: 0.278 ± 0.012	0.8TrpIle: 0.8 ± 0.025	0.892TrpLys: 0.892 ± 0.028	1.18TrpLeu: 1.18 ± 0.035	0.364TrpMet: 0.364 ± 0.016	0.783TrpAsn: 0.783 ± 0.025	0.368TrpPro: 0.368 ± 0.019	0.574TrpGln: 0.574 ± 0.021	0.679TrpArg: 0.679 ± 0.021	0.754TrpSer: 0.754 ± 0.022	0.715TrpThr: 0.715 ± 0.024	0.742TrpVal: 0.742 ± 0.025	0.208TrpTrp: 0.208 ± 0.013	0.522TrpTyr: 0.522 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.113TyrAla: 3.113 ± 0.057	0.312TyrCys: 0.312 ± 0.015	2.497TyrAsp: 2.497 ± 0.046	2.355TyrGlu: 2.355 ± 0.038	2.302TyrPhe: 2.302 ± 0.039	3.13TyrGly: 3.13 ± 0.042	0.959TyrHis: 0.959 ± 0.027	2.643TyrIle: 2.643 ± 0.048	2.408TyrLys: 2.408 ± 0.039	3.945TyrLeu: 3.945 ± 0.057	0.946TyrMet: 0.946 ± 0.029	2.451TyrAsn: 2.451 ± 0.053	1.728TyrPro: 1.728 ± 0.037	1.771TyrGln: 1.771 ± 0.037	2.295TyrArg: 2.295 ± 0.042	2.506TyrSer: 2.506 ± 0.048	2.628TyrThr: 2.628 ± 0.044	2.424TyrVal: 2.424 ± 0.04	0.586TyrTrp: 0.586 ± 0.02	1.957TyrTyr: 1.957 ± 0.046	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3791 proteins (1386281 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---