Amino acid dipepetide frequency for Tortoise microvirus 23

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.601AlaAla: 1.601 ± 1.559
0.801AlaCys: 0.801 ± 0.753
4.003AlaAsp: 4.003 ± 1.417
2.402AlaGlu: 2.402 ± 0.988
2.402AlaPhe: 2.402 ± 0.988
4.003AlaGly: 4.003 ± 1.487
0.801AlaHis: 0.801 ± 0.753
3.203AlaIle: 3.203 ± 0.703
0.0AlaLys: 0.0 ± 0.0
4.003AlaLeu: 4.003 ± 1.303
0.801AlaMet: 0.801 ± 0.753
6.405AlaAsn: 6.405 ± 2.166
2.402AlaPro: 2.402 ± 1.111
2.402AlaGln: 2.402 ± 1.58
3.203AlaArg: 3.203 ± 1.412
2.402AlaSer: 2.402 ± 1.242
2.402AlaThr: 2.402 ± 0.656
5.604AlaVal: 5.604 ± 1.54
2.402AlaTrp: 2.402 ± 0.656
2.402AlaTyr: 2.402 ± 1.401
0.0AlaXaa: 0.0 ± 0.0
Cys
0.801CysAla: 0.801 ± 0.753
0.801CysCys: 0.801 ± 0.528
3.203CysAsp: 3.203 ± 1.169
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.801CysGly: 0.801 ± 0.753
0.0CysHis: 0.0 ± 0.0
0.801CysIle: 0.801 ± 0.753
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.801CysGln: 0.801 ± 0.528
1.601CysArg: 1.601 ± 1.506
0.801CysSer: 0.801 ± 0.753
0.801CysThr: 0.801 ± 0.528
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.801CysTyr: 0.801 ± 0.753
0.0CysXaa: 0.0 ± 0.0
Asp
2.402AspAla: 2.402 ± 1.401
0.0AspCys: 0.0 ± 0.0
0.801AspAsp: 0.801 ± 0.753
3.203AspGlu: 3.203 ± 1.217
4.003AspPhe: 4.003 ± 2.348
3.203AspGly: 3.203 ± 2.11
0.801AspHis: 0.801 ± 0.528
4.804AspIle: 4.804 ± 1.252
2.402AspLys: 2.402 ± 1.3
4.003AspLeu: 4.003 ± 1.476
1.601AspMet: 1.601 ± 1.099
3.203AspAsn: 3.203 ± 1.433
2.402AspPro: 2.402 ± 1.294
0.801AspGln: 0.801 ± 0.528
0.801AspArg: 0.801 ± 0.78
5.604AspSer: 5.604 ± 2.902
2.402AspThr: 2.402 ± 2.512
3.203AspVal: 3.203 ± 1.412
1.601AspTrp: 1.601 ± 1.506
5.604AspTyr: 5.604 ± 1.142
0.0AspXaa: 0.0 ± 0.0
Glu
3.203GluAla: 3.203 ± 1.433
0.801GluCys: 0.801 ± 0.528
3.203GluAsp: 3.203 ± 1.412
2.402GluGlu: 2.402 ± 1.766
2.402GluPhe: 2.402 ± 1.583
2.402GluGly: 2.402 ± 1.54
2.402GluHis: 2.402 ± 0.94
3.203GluIle: 3.203 ± 1.58
1.601GluLys: 1.601 ± 0.668
6.405GluLeu: 6.405 ± 4.551
0.801GluMet: 0.801 ± 1.021
7.206GluAsn: 7.206 ± 3.038
3.203GluPro: 3.203 ± 1.03
2.402GluGln: 2.402 ± 0.988
8.006GluArg: 8.006 ± 2.65
4.003GluSer: 4.003 ± 1.314
5.604GluThr: 5.604 ± 2.021
3.203GluVal: 3.203 ± 2.11
0.801GluTrp: 0.801 ± 1.262
4.003GluTyr: 4.003 ± 1.889
0.0GluXaa: 0.0 ± 0.0
Phe
1.601PheAla: 1.601 ± 1.055
0.0PheCys: 0.0 ± 0.0
3.203PheAsp: 3.203 ± 1.651
3.203PheGlu: 3.203 ± 1.22
4.003PhePhe: 4.003 ± 3.772
3.203PheGly: 3.203 ± 2.11
0.801PheHis: 0.801 ± 1.262
1.601PheIle: 1.601 ± 1.055
4.003PheLys: 4.003 ± 1.417
8.006PheLeu: 8.006 ± 4.24
0.0PheMet: 0.0 ± 0.0
4.804PheAsn: 4.804 ± 3.492
1.601PhePro: 1.601 ± 1.055
2.402PheGln: 2.402 ± 1.583
1.601PheArg: 1.601 ± 1.055
4.804PheSer: 4.804 ± 1.344
2.402PheThr: 2.402 ± 1.583
4.003PheVal: 4.003 ± 2.247
0.801PheTrp: 0.801 ± 0.528
0.801PheTyr: 0.801 ± 0.753
0.0PheXaa: 0.0 ± 0.0
Gly
5.604GlyAla: 5.604 ± 1.253
0.0GlyCys: 0.0 ± 0.0
1.601GlyAsp: 1.601 ± 1.055
3.203GlyGlu: 3.203 ± 1.37
2.402GlyPhe: 2.402 ± 1.322
3.203GlyGly: 3.203 ± 1.37
0.801GlyHis: 0.801 ± 0.528
3.203GlyIle: 3.203 ± 1.574
3.203GlyLys: 3.203 ± 2.564
3.203GlyLeu: 3.203 ± 1.433
0.801GlyMet: 0.801 ± 0.78
3.203GlyAsn: 3.203 ± 2.11
0.0GlyPro: 0.0 ± 0.0
2.402GlyGln: 2.402 ± 1.242
1.601GlyArg: 1.601 ± 0.668
7.206GlySer: 7.206 ± 1.314
2.402GlyThr: 2.402 ± 1.583
2.402GlyVal: 2.402 ± 1.583
0.0GlyTrp: 0.0 ± 0.0
4.003GlyTyr: 4.003 ± 2.638
0.0GlyXaa: 0.0 ± 0.0
His
0.801HisAla: 0.801 ± 0.753
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.801HisGlu: 0.801 ± 1.133
0.801HisPhe: 0.801 ± 0.528
3.203HisGly: 3.203 ± 1.37
0.0HisHis: 0.0 ± 0.0
0.801HisIle: 0.801 ± 0.753
1.601HisLys: 1.601 ± 1.506
1.601HisLeu: 1.601 ± 1.055
0.0HisMet: 0.0 ± 0.0
1.601HisAsn: 1.601 ± 0.668
1.601HisPro: 1.601 ± 0.668
0.801HisGln: 0.801 ± 0.528
0.801HisArg: 0.801 ± 0.528
0.801HisSer: 0.801 ± 1.262
0.0HisThr: 0.0 ± 0.0
1.601HisVal: 1.601 ± 1.055
0.0HisTrp: 0.0 ± 0.0
4.003HisTyr: 4.003 ± 2.784
0.0HisXaa: 0.0 ± 0.0
Ile
1.601IleAla: 1.601 ± 1.297
0.801IleCys: 0.801 ± 0.528
2.402IleAsp: 2.402 ± 0.94
3.203IleGlu: 3.203 ± 2.63
1.601IlePhe: 1.601 ± 1.055
2.402IleGly: 2.402 ± 1.468
0.0IleHis: 0.0 ± 0.0
0.801IleIle: 0.801 ± 0.78
3.203IleLys: 3.203 ± 3.011
6.405IleLeu: 6.405 ± 1.645
2.402IleMet: 2.402 ± 0.94
4.804IleAsn: 4.804 ± 1.834
3.203IlePro: 3.203 ± 2.437
1.601IleGln: 1.601 ± 1.506
4.003IleArg: 4.003 ± 1.056
2.402IleSer: 2.402 ± 0.94
2.402IleThr: 2.402 ± 0.94
1.601IleVal: 1.601 ± 1.719
1.601IleTrp: 1.601 ± 0.668
3.203IleTyr: 3.203 ± 0.703
0.0IleXaa: 0.0 ± 0.0
Lys
0.801LysAla: 0.801 ± 0.78
0.0LysCys: 0.0 ± 0.0
7.206LysAsp: 7.206 ± 2.367
5.604LysGlu: 5.604 ± 1.77
4.003LysPhe: 4.003 ± 1.997
4.804LysGly: 4.804 ± 1.67
0.801LysHis: 0.801 ± 0.753
4.804LysIle: 4.804 ± 2.754
9.608LysLys: 9.608 ± 4.264
2.402LysLeu: 2.402 ± 1.981
0.801LysMet: 0.801 ± 0.674
2.402LysAsn: 2.402 ± 1.468
1.601LysPro: 1.601 ± 1.326
0.801LysGln: 0.801 ± 0.78
2.402LysArg: 2.402 ± 1.322
4.003LysSer: 4.003 ± 1.422
4.804LysThr: 4.804 ± 2.031
2.402LysVal: 2.402 ± 0.988
0.0LysTrp: 0.0 ± 0.0
4.804LysTyr: 4.804 ± 2.642
0.0LysXaa: 0.0 ± 0.0
Leu
3.203LeuAla: 3.203 ± 1.433
1.601LeuCys: 1.601 ± 1.326
4.804LeuAsp: 4.804 ± 2.439
8.006LeuGlu: 8.006 ± 1.104
4.003LeuPhe: 4.003 ± 2.405
3.203LeuGly: 3.203 ± 2.11
0.801LeuHis: 0.801 ± 0.528
5.604LeuIle: 5.604 ± 1.874
7.206LeuLys: 7.206 ± 1.847
2.402LeuLeu: 2.402 ± 1.294
6.405LeuMet: 6.405 ± 1.758
5.604LeuAsn: 5.604 ± 1.863
8.006LeuPro: 8.006 ± 2.684
6.405LeuGln: 6.405 ± 1.682
2.402LeuArg: 2.402 ± 0.656
7.206LeuSer: 7.206 ± 2.508
4.804LeuThr: 4.804 ± 3.677
1.601LeuVal: 1.601 ± 1.055
0.801LeuTrp: 0.801 ± 1.262
2.402LeuTyr: 2.402 ± 1.294
0.0LeuXaa: 0.0 ± 0.0
Met
4.003MetAla: 4.003 ± 2.063
0.801MetCys: 0.801 ± 0.753
0.0MetAsp: 0.0 ± 0.0
0.801MetGlu: 0.801 ± 0.753
0.801MetPhe: 0.801 ± 0.753
1.601MetGly: 1.601 ± 0.716
0.801MetHis: 0.801 ± 0.528
0.801MetIle: 0.801 ± 0.753
3.203MetLys: 3.203 ± 1.716
1.601MetLeu: 1.601 ± 0.668
0.0MetMet: 0.0 ± 0.0
0.801MetAsn: 0.801 ± 0.78
0.0MetPro: 0.0 ± 0.0
2.402MetGln: 2.402 ± 1.54
1.601MetArg: 1.601 ± 0.961
0.801MetSer: 0.801 ± 1.262
0.801MetThr: 0.801 ± 0.528
2.402MetVal: 2.402 ± 1.3
0.0MetTrp: 0.0 ± 0.0
0.801MetTyr: 0.801 ± 0.528
0.0MetXaa: 0.0 ± 0.0
Asn
3.203AsnAla: 3.203 ± 1.277
0.0AsnCys: 0.0 ± 0.0
2.402AsnAsp: 2.402 ± 1.242
7.206AsnGlu: 7.206 ± 2.486
0.801AsnPhe: 0.801 ± 0.528
0.0AsnGly: 0.0 ± 0.0
1.601AsnHis: 1.601 ± 1.099
4.804AsnIle: 4.804 ± 1.583
6.405AsnLys: 6.405 ± 2.474
4.003AsnLeu: 4.003 ± 1.149
1.601AsnMet: 1.601 ± 1.055
5.604AsnAsn: 5.604 ± 3.264
6.405AsnPro: 6.405 ± 2.377
3.203AsnGln: 3.203 ± 2.151
3.203AsnArg: 3.203 ± 1.531
4.003AsnSer: 4.003 ± 0.835
2.402AsnThr: 2.402 ± 1.322
2.402AsnVal: 2.402 ± 1.583
0.0AsnTrp: 0.0 ± 0.0
4.003AsnTyr: 4.003 ± 2.666
0.0AsnXaa: 0.0 ± 0.0
Pro
3.203ProAla: 3.203 ± 1.58
1.601ProCys: 1.601 ± 1.506
2.402ProAsp: 2.402 ± 2.348
3.203ProGlu: 3.203 ± 1.169
4.003ProPhe: 4.003 ± 2.405
1.601ProGly: 1.601 ± 0.668
0.801ProHis: 0.801 ± 0.753
4.003ProIle: 4.003 ± 1.851
0.0ProLys: 0.0 ± 0.0
4.003ProLeu: 4.003 ± 1.955
0.0ProMet: 0.0 ± 0.0
3.203ProAsn: 3.203 ± 1.574
0.801ProPro: 0.801 ± 0.528
4.003ProGln: 4.003 ± 2.079
2.402ProArg: 2.402 ± 0.94
4.003ProSer: 4.003 ± 1.392
4.003ProThr: 4.003 ± 2.348
6.405ProVal: 6.405 ± 1.317
1.601ProTrp: 1.601 ± 0.716
2.402ProTyr: 2.402 ± 1.816
0.0ProXaa: 0.0 ± 0.0
Gln
4.003GlnAla: 4.003 ± 2.084
0.801GlnCys: 0.801 ± 0.528
0.0GlnAsp: 0.0 ± 0.0
2.402GlnGlu: 2.402 ± 0.988
1.601GlnPhe: 1.601 ± 1.164
0.801GlnGly: 0.801 ± 0.528
0.801GlnHis: 0.801 ± 0.753
0.0GlnIle: 0.0 ± 0.0
6.405GlnLys: 6.405 ± 1.773
8.006GlnLeu: 8.006 ± 4.022
2.402GlnMet: 2.402 ± 1.58
1.601GlnAsn: 1.601 ± 0.716
1.601GlnPro: 1.601 ± 1.055
4.003GlnGln: 4.003 ± 2.221
4.003GlnArg: 4.003 ± 1.417
4.804GlnSer: 4.804 ± 1.252
3.203GlnThr: 3.203 ± 1.169
1.601GlnVal: 1.601 ± 1.164
0.801GlnTrp: 0.801 ± 0.753
0.801GlnTyr: 0.801 ± 0.78
0.0GlnXaa: 0.0 ± 0.0
Arg
1.601ArgAla: 1.601 ± 1.099
0.801ArgCys: 0.801 ± 0.753
4.804ArgAsp: 4.804 ± 1.154
3.203ArgGlu: 3.203 ± 2.151
3.203ArgPhe: 3.203 ± 1.37
2.402ArgGly: 2.402 ± 1.583
0.0ArgHis: 0.0 ± 0.0
0.801ArgIle: 0.801 ± 0.528
4.804ArgLys: 4.804 ± 2.089
7.206ArgLeu: 7.206 ± 0.89
0.801ArgMet: 0.801 ± 0.78
1.601ArgAsn: 1.601 ± 1.297
2.402ArgPro: 2.402 ± 1.583
1.601ArgGln: 1.601 ± 1.055
4.804ArgArg: 4.804 ± 1.584
2.402ArgSer: 2.402 ± 2.623
0.801ArgThr: 0.801 ± 0.528
0.801ArgVal: 0.801 ± 0.753
2.402ArgTrp: 2.402 ± 0.988
6.405ArgTyr: 6.405 ± 2.19
0.0ArgXaa: 0.0 ± 0.0
Ser
7.206SerAla: 7.206 ± 2.389
0.0SerCys: 0.0 ± 0.0
3.203SerAsp: 3.203 ± 1.065
6.405SerGlu: 6.405 ± 3.193
6.405SerPhe: 6.405 ± 3.119
4.804SerGly: 4.804 ± 2.483
0.801SerHis: 0.801 ± 0.753
3.203SerIle: 3.203 ± 2.272
2.402SerLys: 2.402 ± 1.54
5.604SerLeu: 5.604 ± 2.547
2.402SerMet: 2.402 ± 1.442
2.402SerAsn: 2.402 ± 0.988
7.206SerPro: 7.206 ± 2.231
4.003SerGln: 4.003 ± 2.41
3.203SerArg: 3.203 ± 1.527
4.804SerSer: 4.804 ± 1.019
3.203SerThr: 3.203 ± 1.37
4.804SerVal: 4.804 ± 4.725
0.0SerTrp: 0.0 ± 0.0
3.203SerTyr: 3.203 ± 2.272
0.0SerXaa: 0.0 ± 0.0
Thr
3.203ThrAla: 3.203 ± 1.598
0.801ThrCys: 0.801 ± 0.528
3.203ThrAsp: 3.203 ± 1.484
2.402ThrGlu: 2.402 ± 1.322
3.203ThrPhe: 3.203 ± 0.703
4.003ThrGly: 4.003 ± 1.851
2.402ThrHis: 2.402 ± 2.258
3.203ThrIle: 3.203 ± 1.169
3.203ThrLys: 3.203 ± 2.045
8.807ThrLeu: 8.807 ± 2.984
0.801ThrMet: 0.801 ± 0.753
2.402ThrAsn: 2.402 ± 1.3
4.003ThrPro: 4.003 ± 2.102
1.601ThrGln: 1.601 ± 0.716
0.0ThrArg: 0.0 ± 0.0
3.203ThrSer: 3.203 ± 1.169
1.601ThrThr: 1.601 ± 1.055
1.601ThrVal: 1.601 ± 1.099
0.0ThrTrp: 0.0 ± 0.0
1.601ThrTyr: 1.601 ± 0.961
0.0ThrXaa: 0.0 ± 0.0
Val
2.402ValAla: 2.402 ± 0.656
0.0ValCys: 0.0 ± 0.0
1.601ValAsp: 1.601 ± 1.055
2.402ValGlu: 2.402 ± 1.3
0.801ValPhe: 0.801 ± 0.528
3.203ValGly: 3.203 ± 1.412
4.804ValHis: 4.804 ± 2.352
1.601ValIle: 1.601 ± 1.467
1.601ValLys: 1.601 ± 2.523
4.804ValLeu: 4.804 ± 2.445
1.601ValMet: 1.601 ± 1.164
2.402ValAsn: 2.402 ± 0.988
4.804ValPro: 4.804 ± 1.019
0.801ValGln: 0.801 ± 0.528
4.003ValArg: 4.003 ± 2.079
7.206ValSer: 7.206 ± 4.566
2.402ValThr: 2.402 ± 1.133
4.003ValVal: 4.003 ± 1.071
0.801ValTrp: 0.801 ± 0.528
0.801ValTyr: 0.801 ± 0.78
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.801TrpCys: 0.801 ± 0.753
0.0TrpAsp: 0.0 ± 0.0
1.601TrpGlu: 1.601 ± 0.716
2.402TrpPhe: 2.402 ± 2.37
0.0TrpGly: 0.0 ± 0.0
0.801TrpHis: 0.801 ± 0.528
0.801TrpIle: 0.801 ± 0.78
0.0TrpLys: 0.0 ± 0.0
0.801TrpLeu: 0.801 ± 0.753
0.0TrpMet: 0.0 ± 0.0
2.402TrpAsn: 2.402 ± 0.94
0.801TrpPro: 0.801 ± 0.528
0.0TrpGln: 0.0 ± 0.0
0.801TrpArg: 0.801 ± 0.78
0.0TrpSer: 0.0 ± 0.0
1.601TrpThr: 1.601 ± 0.668
0.0TrpVal: 0.0 ± 0.0
0.801TrpTrp: 0.801 ± 0.78
0.801TrpTyr: 0.801 ± 0.753
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.203TyrAla: 3.203 ± 2.11
0.801TyrCys: 0.801 ± 0.753
4.804TyrAsp: 4.804 ± 1.556
5.604TyrGlu: 5.604 ± 2.227
4.003TyrPhe: 4.003 ± 1.27
1.601TyrGly: 1.601 ± 0.961
0.801TyrHis: 0.801 ± 0.753
1.601TyrIle: 1.601 ± 1.506
3.203TyrLys: 3.203 ± 1.065
3.203TyrLeu: 3.203 ± 1.336
0.0TyrMet: 0.0 ± 0.0
1.601TyrAsn: 1.601 ± 1.559
1.601TyrPro: 1.601 ± 1.164
7.206TyrGln: 7.206 ± 4.287
2.402TyrArg: 2.402 ± 1.58
5.604TyrSer: 5.604 ± 2.194
3.203TyrThr: 3.203 ± 1.37
2.402TyrVal: 2.402 ± 1.322
0.0TyrTrp: 0.0 ± 0.0
1.601TyrTyr: 1.601 ± 1.326
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1250 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski