Amino acid dipepetide frequency for Ictalurid herpesvirus 1 (strain Auburn) (IcHV-1) (Channel catfish herpesvirus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.633AlaAla: 6.633 ± 0.656
1.327AlaCys: 1.327 ± 0.263
3.596AlaAsp: 3.596 ± 0.394
3.714AlaGlu: 3.714 ± 0.404
2.535AlaPhe: 2.535 ± 0.291
5.041AlaGly: 5.041 ± 0.69
2.063AlaHis: 2.063 ± 0.279
3.921AlaIle: 3.921 ± 0.451
2.918AlaLys: 2.918 ± 0.519
7.311AlaLeu: 7.311 ± 0.541
2.211AlaMet: 2.211 ± 0.319
2.742AlaAsn: 2.742 ± 1.023
5.336AlaPro: 5.336 ± 0.549
2.122AlaGln: 2.122 ± 0.296
4.805AlaArg: 4.805 ± 0.427
3.803AlaSer: 3.803 ± 0.37
5.719AlaThr: 5.719 ± 0.708
6.338AlaVal: 6.338 ± 0.421
0.707AlaTrp: 0.707 ± 0.139
1.798AlaTyr: 1.798 ± 0.265
0.0AlaXaa: 0.0 ± 0.0
Cys
1.562CysAla: 1.562 ± 0.17
0.531CysCys: 0.531 ± 0.182
1.268CysAsp: 1.268 ± 0.212
1.179CysGlu: 1.179 ± 0.201
0.619CysPhe: 0.619 ± 0.182
1.975CysGly: 1.975 ± 0.416
0.354CysHis: 0.354 ± 0.093
0.707CysIle: 0.707 ± 0.157
0.796CysLys: 0.796 ± 0.2
1.474CysLeu: 1.474 ± 0.208
0.295CysMet: 0.295 ± 0.086
0.56CysAsn: 0.56 ± 0.15
1.091CysPro: 1.091 ± 0.203
0.442CysGln: 0.442 ± 0.14
0.766CysArg: 0.766 ± 0.147
0.943CysSer: 0.943 ± 0.143
1.444CysThr: 1.444 ± 0.203
1.327CysVal: 1.327 ± 0.199
0.265CysTrp: 0.265 ± 0.108
0.56CysTyr: 0.56 ± 0.124
0.0CysXaa: 0.0 ± 0.0
Asp
3.862AspAla: 3.862 ± 0.303
0.678AspCys: 0.678 ± 0.168
4.333AspAsp: 4.333 ± 0.534
3.567AspGlu: 3.567 ± 0.385
2.624AspPhe: 2.624 ± 0.255
3.685AspGly: 3.685 ± 0.36
1.238AspHis: 1.238 ± 0.184
3.184AspIle: 3.184 ± 0.362
1.444AspLys: 1.444 ± 0.211
6.132AspLeu: 6.132 ± 0.668
1.356AspMet: 1.356 ± 0.208
1.385AspAsn: 1.385 ± 0.223
3.773AspPro: 3.773 ± 0.304
1.268AspGln: 1.268 ± 0.205
4.834AspArg: 4.834 ± 0.522
3.773AspSer: 3.773 ± 0.432
3.891AspThr: 3.891 ± 0.627
3.272AspVal: 3.272 ± 0.337
0.737AspTrp: 0.737 ± 0.179
1.327AspTyr: 1.327 ± 0.188
0.0AspXaa: 0.0 ± 0.0
Glu
4.215GluAla: 4.215 ± 0.407
1.15GluCys: 1.15 ± 0.242
2.329GluAsp: 2.329 ± 0.249
3.449GluGlu: 3.449 ± 0.518
2.005GluPhe: 2.005 ± 0.242
2.889GluGly: 2.889 ± 0.369
1.15GluHis: 1.15 ± 0.179
2.712GluIle: 2.712 ± 0.301
3.036GluLys: 3.036 ± 0.325
6.839GluLeu: 6.839 ± 0.531
2.005GluMet: 2.005 ± 0.243
2.093GluAsn: 2.093 ± 0.281
3.596GluPro: 3.596 ± 0.423
1.238GluGln: 1.238 ± 0.24
4.54GluArg: 4.54 ± 0.449
4.098GluSer: 4.098 ± 0.536
4.186GluThr: 4.186 ± 0.42
3.184GluVal: 3.184 ± 0.252
1.032GluTrp: 1.032 ± 0.175
1.946GluTyr: 1.946 ± 0.274
0.0GluXaa: 0.0 ± 0.0
Phe
1.975PheAla: 1.975 ± 0.24
1.179PheCys: 1.179 ± 0.243
2.152PheAsp: 2.152 ± 0.33
1.68PheGlu: 1.68 ± 0.237
1.946PhePhe: 1.946 ± 0.273
3.066PheGly: 3.066 ± 0.254
0.973PheHis: 0.973 ± 0.193
2.447PheIle: 2.447 ± 0.349
2.122PheLys: 2.122 ± 0.313
3.773PheLeu: 3.773 ± 0.416
1.268PheMet: 1.268 ± 0.206
1.916PheAsn: 1.916 ± 0.268
1.71PhePro: 1.71 ± 0.259
1.179PheGln: 1.179 ± 0.215
2.8PheArg: 2.8 ± 0.303
2.683PheSer: 2.683 ± 0.359
2.8PheThr: 2.8 ± 0.315
2.83PheVal: 2.83 ± 0.36
0.855PheTrp: 0.855 ± 0.197
0.855PheTyr: 0.855 ± 0.155
0.0PheXaa: 0.0 ± 0.0
Gly
6.367GlyAla: 6.367 ± 1.042
1.327GlyCys: 1.327 ± 0.244
4.422GlyAsp: 4.422 ± 0.389
4.156GlyGlu: 4.156 ± 0.359
3.243GlyPhe: 3.243 ± 0.291
5.748GlyGly: 5.748 ± 0.368
1.798GlyHis: 1.798 ± 0.389
3.449GlyIle: 3.449 ± 0.313
2.977GlyLys: 2.977 ± 0.308
7.016GlyLeu: 7.016 ± 0.579
1.503GlyMet: 1.503 ± 0.204
1.828GlyAsn: 1.828 ± 0.321
3.449GlyPro: 3.449 ± 0.361
1.209GlyGln: 1.209 ± 0.221
3.803GlyArg: 3.803 ± 0.383
4.923GlySer: 4.923 ± 0.308
5.542GlyThr: 5.542 ± 0.584
5.719GlyVal: 5.719 ± 0.335
0.737GlyTrp: 0.737 ± 0.156
1.946GlyTyr: 1.946 ± 0.264
0.0GlyXaa: 0.0 ± 0.0
His
1.68HisAla: 1.68 ± 0.259
0.354HisCys: 0.354 ± 0.096
1.002HisAsp: 1.002 ± 0.156
1.415HisGlu: 1.415 ± 0.204
0.884HisPhe: 0.884 ± 0.178
2.476HisGly: 2.476 ± 0.358
0.501HisHis: 0.501 ± 0.148
1.061HisIle: 1.061 ± 0.17
0.943HisLys: 0.943 ± 0.237
1.975HisLeu: 1.975 ± 0.211
1.002HisMet: 1.002 ± 0.163
0.619HisAsn: 0.619 ± 0.151
1.385HisPro: 1.385 ± 0.271
0.59HisGln: 0.59 ± 0.155
1.946HisArg: 1.946 ± 0.22
0.943HisSer: 0.943 ± 0.145
1.209HisThr: 1.209 ± 0.206
2.005HisVal: 2.005 ± 0.223
0.147HisTrp: 0.147 ± 0.061
0.56HisTyr: 0.56 ± 0.112
0.0HisXaa: 0.0 ± 0.0
Ile
3.39IleAla: 3.39 ± 0.312
1.061IleCys: 1.061 ± 0.177
3.243IleAsp: 3.243 ± 0.284
3.213IleGlu: 3.213 ± 0.323
2.742IlePhe: 2.742 ± 0.296
3.655IleGly: 3.655 ± 0.28
1.179IleHis: 1.179 ± 0.16
3.066IleIle: 3.066 ± 0.33
2.329IleLys: 2.329 ± 0.34
4.363IleLeu: 4.363 ± 0.412
1.415IleMet: 1.415 ± 0.187
2.122IleAsn: 2.122 ± 0.297
4.422IlePro: 4.422 ± 0.3
1.68IleGln: 1.68 ± 0.326
3.007IleArg: 3.007 ± 0.259
3.567IleSer: 3.567 ± 0.27
5.041IleThr: 5.041 ± 0.364
3.42IleVal: 3.42 ± 0.429
0.707IleTrp: 0.707 ± 0.131
1.828IleTyr: 1.828 ± 0.232
0.0IleXaa: 0.0 ± 0.0
Lys
2.506LysAla: 2.506 ± 0.407
1.032LysCys: 1.032 ± 0.201
1.238LysAsp: 1.238 ± 0.198
1.651LysGlu: 1.651 ± 0.304
1.503LysPhe: 1.503 ± 0.239
2.299LysGly: 2.299 ± 0.305
0.796LysHis: 0.796 ± 0.131
3.125LysIle: 3.125 ± 0.42
3.007LysLys: 3.007 ± 0.653
4.363LysLeu: 4.363 ± 0.364
1.68LysMet: 1.68 ± 0.308
2.093LysAsn: 2.093 ± 0.28
2.535LysPro: 2.535 ± 0.602
0.825LysGln: 0.825 ± 0.134
3.773LysArg: 3.773 ± 0.398
2.889LysSer: 2.889 ± 0.396
3.243LysThr: 3.243 ± 0.333
2.712LysVal: 2.712 ± 0.4
0.766LysTrp: 0.766 ± 0.16
1.415LysTyr: 1.415 ± 0.158
0.0LysXaa: 0.0 ± 0.0
Leu
6.22LeuAla: 6.22 ± 0.502
1.415LeuCys: 1.415 ± 0.192
5.454LeuAsp: 5.454 ± 0.587
5.778LeuGlu: 5.778 ± 0.514
3.714LeuPhe: 3.714 ± 0.417
6.751LeuGly: 6.751 ± 0.527
2.063LeuHis: 2.063 ± 0.286
4.864LeuIle: 4.864 ± 0.415
4.333LeuLys: 4.333 ± 0.289
8.254LeuLeu: 8.254 ± 0.478
2.771LeuMet: 2.771 ± 0.339
3.361LeuAsn: 3.361 ± 0.379
4.746LeuPro: 4.746 ± 0.655
2.181LeuGln: 2.181 ± 0.248
5.483LeuArg: 5.483 ± 0.413
7.045LeuSer: 7.045 ± 0.447
6.367LeuThr: 6.367 ± 0.634
6.692LeuVal: 6.692 ± 0.489
1.061LeuTrp: 1.061 ± 0.193
2.594LeuTyr: 2.594 ± 0.303
0.0LeuXaa: 0.0 ± 0.0
Met
2.27MetAla: 2.27 ± 0.271
0.766MetCys: 0.766 ± 0.167
2.299MetAsp: 2.299 ± 0.286
2.181MetGlu: 2.181 ± 0.261
0.855MetPhe: 0.855 ± 0.141
2.093MetGly: 2.093 ± 0.258
0.472MetHis: 0.472 ± 0.103
1.857MetIle: 1.857 ± 0.244
1.209MetLys: 1.209 ± 0.21
1.739MetLeu: 1.739 ± 0.242
1.002MetMet: 1.002 ± 0.174
1.002MetAsn: 1.002 ± 0.129
1.002MetPro: 1.002 ± 0.336
0.383MetGln: 0.383 ± 0.12
1.327MetArg: 1.327 ± 0.227
1.887MetSer: 1.887 ± 0.234
1.975MetThr: 1.975 ± 0.161
2.034MetVal: 2.034 ± 0.238
0.354MetTrp: 0.354 ± 0.097
1.327MetTyr: 1.327 ± 0.224
0.0MetXaa: 0.0 ± 0.0
Asn
2.122AsnAla: 2.122 ± 0.259
0.56AsnCys: 0.56 ± 0.121
1.68AsnAsp: 1.68 ± 0.475
1.533AsnGlu: 1.533 ± 0.177
1.651AsnPhe: 1.651 ± 0.2
2.8AsnGly: 2.8 ± 0.323
0.707AsnHis: 0.707 ± 0.143
2.388AsnIle: 2.388 ± 0.323
1.71AsnLys: 1.71 ± 0.234
3.066AsnLeu: 3.066 ± 0.292
0.943AsnMet: 0.943 ± 0.145
1.415AsnAsn: 1.415 ± 0.22
2.388AsnPro: 2.388 ± 0.263
1.061AsnGln: 1.061 ± 0.187
2.329AsnArg: 2.329 ± 0.293
1.975AsnSer: 1.975 ± 0.247
2.683AsnThr: 2.683 ± 0.266
2.299AsnVal: 2.299 ± 0.24
0.501AsnTrp: 0.501 ± 0.129
0.59AsnTyr: 0.59 ± 0.157
0.0AsnXaa: 0.0 ± 0.0
Pro
5.395ProAla: 5.395 ± 1.07
0.855ProCys: 0.855 ± 0.17
2.83ProAsp: 2.83 ± 0.3
4.392ProGlu: 4.392 ± 0.38
1.975ProPhe: 1.975 ± 0.255
4.451ProGly: 4.451 ± 0.402
1.415ProHis: 1.415 ± 0.247
3.508ProIle: 3.508 ± 0.268
2.388ProLys: 2.388 ± 0.301
3.714ProLeu: 3.714 ± 0.301
1.68ProMet: 1.68 ± 0.246
1.562ProAsn: 1.562 ± 0.208
5.306ProPro: 5.306 ± 0.677
1.592ProGln: 1.592 ± 0.335
4.451ProArg: 4.451 ± 0.396
4.127ProSer: 4.127 ± 0.455
4.245ProThr: 4.245 ± 0.69
5.837ProVal: 5.837 ± 0.529
0.56ProTrp: 0.56 ± 0.125
1.15ProTyr: 1.15 ± 0.181
0.0ProXaa: 0.0 ± 0.0
Gln
1.474GlnAla: 1.474 ± 0.232
0.531GlnCys: 0.531 ± 0.132
0.707GlnAsp: 0.707 ± 0.153
1.091GlnGlu: 1.091 ± 0.16
1.209GlnPhe: 1.209 ± 0.243
1.15GlnGly: 1.15 ± 0.21
0.678GlnHis: 0.678 ± 0.149
1.385GlnIle: 1.385 ± 0.175
1.268GlnLys: 1.268 ± 0.251
3.213GlnLeu: 3.213 ± 0.294
0.56GlnMet: 0.56 ± 0.118
1.061GlnAsn: 1.061 ± 0.178
1.592GlnPro: 1.592 ± 0.354
0.884GlnGln: 0.884 ± 0.218
1.769GlnArg: 1.769 ± 0.276
1.327GlnSer: 1.327 ± 0.268
1.68GlnThr: 1.68 ± 0.266
1.327GlnVal: 1.327 ± 0.209
0.265GlnTrp: 0.265 ± 0.077
0.943GlnTyr: 0.943 ± 0.185
0.0GlnXaa: 0.0 ± 0.0
Arg
6.22ArgAla: 6.22 ± 0.425
1.12ArgCys: 1.12 ± 0.196
4.363ArgAsp: 4.363 ± 0.388
4.039ArgGlu: 4.039 ± 0.457
3.007ArgPhe: 3.007 ± 0.342
5.336ArgGly: 5.336 ± 0.44
1.327ArgHis: 1.327 ± 0.18
2.712ArgIle: 2.712 ± 0.282
3.007ArgLys: 3.007 ± 0.252
6.102ArgLeu: 6.102 ± 0.456
1.415ArgMet: 1.415 ± 0.191
1.828ArgAsn: 1.828 ± 0.245
3.596ArgPro: 3.596 ± 0.436
1.71ArgGln: 1.71 ± 0.22
4.186ArgArg: 4.186 ± 0.467
3.773ArgSer: 3.773 ± 0.352
4.039ArgThr: 4.039 ± 0.32
5.748ArgVal: 5.748 ± 0.51
0.766ArgTrp: 0.766 ± 0.153
1.946ArgTyr: 1.946 ± 0.311
0.0ArgXaa: 0.0 ± 0.0
Ser
4.304SerAla: 4.304 ± 0.355
1.12SerCys: 1.12 ± 0.215
3.921SerAsp: 3.921 ± 0.359
3.95SerGlu: 3.95 ± 0.531
2.506SerPhe: 2.506 ± 0.272
4.215SerGly: 4.215 ± 0.357
1.327SerHis: 1.327 ± 0.217
3.891SerIle: 3.891 ± 0.32
1.975SerLys: 1.975 ± 0.314
5.955SerLeu: 5.955 ± 0.41
2.034SerMet: 2.034 ± 0.253
1.71SerAsn: 1.71 ± 0.184
3.921SerPro: 3.921 ± 0.484
1.415SerGln: 1.415 ± 0.218
4.245SerArg: 4.245 ± 0.463
4.776SerSer: 4.776 ± 0.517
4.864SerThr: 4.864 ± 0.529
5.188SerVal: 5.188 ± 0.438
0.707SerTrp: 0.707 ± 0.158
1.651SerTyr: 1.651 ± 0.184
0.0SerXaa: 0.0 ± 0.0
Thr
6.485ThrAla: 6.485 ± 0.969
1.474ThrCys: 1.474 ± 0.251
4.392ThrAsp: 4.392 ± 0.46
4.333ThrGlu: 4.333 ± 0.425
2.093ThrPhe: 2.093 ± 0.302
7.252ThrGly: 7.252 ± 0.666
1.533ThrHis: 1.533 ± 0.23
3.803ThrIle: 3.803 ± 0.313
2.712ThrLys: 2.712 ± 0.367
6.574ThrLeu: 6.574 ± 0.435
1.651ThrMet: 1.651 ± 0.19
2.683ThrAsn: 2.683 ± 0.297
5.395ThrPro: 5.395 ± 0.795
1.739ThrGln: 1.739 ± 0.256
4.923ThrArg: 4.923 ± 0.328
3.567ThrSer: 3.567 ± 0.395
6.868ThrThr: 6.868 ± 2.04
6.692ThrVal: 6.692 ± 0.698
0.737ThrTrp: 0.737 ± 0.145
1.327ThrTyr: 1.327 ± 0.206
0.0ThrXaa: 0.0 ± 0.0
Val
5.218ValAla: 5.218 ± 0.355
1.12ValCys: 1.12 ± 0.194
4.776ValAsp: 4.776 ± 0.312
4.098ValGlu: 4.098 ± 0.35
3.478ValPhe: 3.478 ± 0.321
3.596ValGly: 3.596 ± 0.374
2.152ValHis: 2.152 ± 0.231
4.746ValIle: 4.746 ± 0.408
3.508ValLys: 3.508 ± 0.403
5.66ValLeu: 5.66 ± 0.421
2.005ValMet: 2.005 ± 0.191
2.624ValAsn: 2.624 ± 0.265
4.333ValPro: 4.333 ± 0.402
1.769ValGln: 1.769 ± 0.228
4.717ValArg: 4.717 ± 0.381
5.247ValSer: 5.247 ± 0.366
7.281ValThr: 7.281 ± 1.013
5.129ValVal: 5.129 ± 0.578
0.59ValTrp: 0.59 ± 0.174
2.977ValTyr: 2.977 ± 0.326
0.0ValXaa: 0.0 ± 0.0
Trp
0.531TrpAla: 0.531 ± 0.124
0.206TrpCys: 0.206 ± 0.082
0.678TrpAsp: 0.678 ± 0.156
0.766TrpGlu: 0.766 ± 0.197
0.678TrpPhe: 0.678 ± 0.138
0.914TrpGly: 0.914 ± 0.189
0.059TrpHis: 0.059 ± 0.044
0.737TrpIle: 0.737 ± 0.166
0.737TrpLys: 0.737 ± 0.157
1.327TrpLeu: 1.327 ± 0.203
0.383TrpMet: 0.383 ± 0.108
0.56TrpAsn: 0.56 ± 0.156
0.324TrpPro: 0.324 ± 0.089
0.236TrpGln: 0.236 ± 0.08
0.619TrpArg: 0.619 ± 0.133
0.855TrpSer: 0.855 ± 0.17
0.825TrpThr: 0.825 ± 0.169
1.032TrpVal: 1.032 ± 0.196
0.118TrpTrp: 0.118 ± 0.052
0.383TrpTyr: 0.383 ± 0.135
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.211TyrAla: 2.211 ± 0.279
0.354TyrCys: 0.354 ± 0.108
1.68TyrAsp: 1.68 ± 0.183
1.503TyrGlu: 1.503 ± 0.26
0.943TyrPhe: 0.943 ± 0.147
1.769TyrGly: 1.769 ± 0.264
0.943TyrHis: 0.943 ± 0.179
1.887TyrIle: 1.887 ± 0.229
1.032TyrLys: 1.032 ± 0.173
2.299TyrLeu: 2.299 ± 0.262
0.825TyrMet: 0.825 ± 0.183
1.238TyrAsn: 1.238 ± 0.199
1.533TyrPro: 1.533 ± 0.224
0.59TyrGln: 0.59 ± 0.204
1.916TyrArg: 1.916 ± 0.267
1.474TyrSer: 1.474 ± 0.232
2.329TyrThr: 2.329 ± 0.271
2.24TyrVal: 2.24 ± 0.309
0.354TyrTrp: 0.354 ± 0.106
0.796TyrTyr: 0.796 ± 0.184
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 76 proteins (33924 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski