Amino acid dipepetide frequency for Salegentibacter mishustinae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.505AlaAla: 4.505 ± 0.073	0.505AlaCys: 0.505 ± 0.022	3.217AlaAsp: 3.217 ± 0.06	5.335AlaGlu: 5.335 ± 0.074	3.309AlaPhe: 3.309 ± 0.059	4.545AlaGly: 4.545 ± 0.071	1.115AlaHis: 1.115 ± 0.031	5.194AlaIle: 5.194 ± 0.083	4.625AlaLys: 4.625 ± 0.083	6.035AlaLeu: 6.035 ± 0.082	1.608AlaMet: 1.608 ± 0.046	3.217AlaAsn: 3.217 ± 0.05	1.966AlaPro: 1.966 ± 0.052	2.44AlaGln: 2.44 ± 0.05	2.338AlaArg: 2.338 ± 0.055	4.078AlaSer: 4.078 ± 0.067	3.376AlaThr: 3.376 ± 0.079	4.18AlaVal: 4.18 ± 0.073	0.643AlaTrp: 0.643 ± 0.024	2.46AlaTyr: 2.46 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.387CysAla: 0.387 ± 0.017	0.086CysCys: 0.086 ± 0.01	0.371CysAsp: 0.371 ± 0.019	0.524CysGlu: 0.524 ± 0.035	0.343CysPhe: 0.343 ± 0.017	0.597CysGly: 0.597 ± 0.032	0.134CysHis: 0.134 ± 0.012	0.457CysIle: 0.457 ± 0.024	0.43CysLys: 0.43 ± 0.022	0.558CysLeu: 0.558 ± 0.024	0.115CysMet: 0.115 ± 0.009	0.339CysAsn: 0.339 ± 0.018	0.315CysPro: 0.315 ± 0.024	0.178CysGln: 0.178 ± 0.013	0.197CysArg: 0.197 ± 0.013	0.498CysSer: 0.498 ± 0.026	0.34CysThr: 0.34 ± 0.017	0.356CysVal: 0.356 ± 0.018	0.045CysTrp: 0.045 ± 0.006	0.256CysTyr: 0.256 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.545AspAla: 3.545 ± 0.062	0.38AspCys: 0.38 ± 0.025	2.834AspAsp: 2.834 ± 0.066	4.388AspGlu: 4.388 ± 0.072	3.838AspPhe: 3.838 ± 0.07	3.559AspGly: 3.559 ± 0.075	0.991AspHis: 0.991 ± 0.032	4.136AspIle: 4.136 ± 0.061	4.037AspLys: 4.037 ± 0.067	5.526AspLeu: 5.526 ± 0.078	1.143AspMet: 1.143 ± 0.036	2.891AspAsn: 2.891 ± 0.068	1.921AspPro: 1.921 ± 0.05	1.603AspGln: 1.603 ± 0.046	2.143AspArg: 2.143 ± 0.048	3.143AspSer: 3.143 ± 0.061	2.474AspThr: 2.474 ± 0.046	3.189AspVal: 3.189 ± 0.054	0.765AspTrp: 0.765 ± 0.032	2.879AspTyr: 2.879 ± 0.054	0.0AspXaa: 0.0 ± 0.0
Glu	5.291GluAla: 5.291 ± 0.101	0.329GluCys: 0.329 ± 0.023	4.727GluAsp: 4.727 ± 0.085	7.131GluGlu: 7.131 ± 0.104	3.61GluPhe: 3.61 ± 0.064	4.434GluGly: 4.434 ± 0.066	1.202GluHis: 1.202 ± 0.038	6.838GluIle: 6.838 ± 0.088	7.077GluLys: 7.077 ± 0.1	6.956GluLeu: 6.956 ± 0.089	1.893GluMet: 1.893 ± 0.044	5.889GluAsn: 5.889 ± 0.084	1.883GluPro: 1.883 ± 0.053	2.342GluGln: 2.342 ± 0.053	2.856GluArg: 2.856 ± 0.056	3.527GluSer: 3.527 ± 0.054	3.995GluThr: 3.995 ± 0.064	5.103GluVal: 5.103 ± 0.087	0.69GluTrp: 0.69 ± 0.029	2.632GluTyr: 2.632 ± 0.052	0.0GluXaa: 0.0 ± 0.0
Phe	3.041PheAla: 3.041 ± 0.057	0.43PheCys: 0.43 ± 0.022	3.069PheAsp: 3.069 ± 0.057	3.882PheGlu: 3.882 ± 0.066	2.827PhePhe: 2.827 ± 0.07	3.626PheGly: 3.626 ± 0.058	0.831PheHis: 0.831 ± 0.026	3.884PheIle: 3.884 ± 0.062	3.816PheLys: 3.816 ± 0.065	4.971PheLeu: 4.971 ± 0.075	1.097PheMet: 1.097 ± 0.033	3.145PheAsn: 3.145 ± 0.064	1.821PhePro: 1.821 ± 0.039	1.798PheGln: 1.798 ± 0.04	1.922PheArg: 1.922 ± 0.046	4.248PheSer: 4.248 ± 0.068	2.955PheThr: 2.955 ± 0.058	2.714PheVal: 2.714 ± 0.049	0.623PheTrp: 0.623 ± 0.025	2.151PheTyr: 2.151 ± 0.049	0.0PheXaa: 0.0 ± 0.0
Gly	4.187GlyAla: 4.187 ± 0.078	0.486GlyCys: 0.486 ± 0.023	3.523GlyAsp: 3.523 ± 0.058	4.524GlyGlu: 4.524 ± 0.073	3.704GlyPhe: 3.704 ± 0.063	4.62GlyGly: 4.62 ± 0.09	1.081GlyHis: 1.081 ± 0.036	5.475GlyIle: 5.475 ± 0.082	5.086GlyLys: 5.086 ± 0.081	5.731GlyLeu: 5.731 ± 0.086	1.701GlyMet: 1.701 ± 0.044	3.74GlyAsn: 3.74 ± 0.073	1.402GlyPro: 1.402 ± 0.039	1.831GlyGln: 1.831 ± 0.044	2.219GlyArg: 2.219 ± 0.051	3.949GlySer: 3.949 ± 0.064	3.625GlyThr: 3.625 ± 0.076	4.204GlyVal: 4.204 ± 0.07	0.802GlyTrp: 0.802 ± 0.033	2.72GlyTyr: 2.72 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	0.862HisAla: 0.862 ± 0.027	0.166HisCys: 0.166 ± 0.013	0.736HisAsp: 0.736 ± 0.027	1.035HisGlu: 1.035 ± 0.033	1.118HisPhe: 1.118 ± 0.033	1.038HisGly: 1.038 ± 0.034	0.468HisHis: 0.468 ± 0.023	1.282HisIle: 1.282 ± 0.039	1.243HisLys: 1.243 ± 0.036	1.792HisLeu: 1.792 ± 0.043	0.288HisMet: 0.288 ± 0.015	0.915HisAsn: 0.915 ± 0.032	0.936HisPro: 0.936 ± 0.032	0.748HisGln: 0.748 ± 0.026	0.706HisArg: 0.706 ± 0.026	1.132HisSer: 1.132 ± 0.04	0.867HisThr: 0.867 ± 0.024	0.797HisVal: 0.797 ± 0.028	0.224HisTrp: 0.224 ± 0.015	0.773HisTyr: 0.773 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.467IleAla: 5.467 ± 0.089	0.527IleCys: 0.527 ± 0.023	4.57IleAsp: 4.57 ± 0.073	5.794IleGlu: 5.794 ± 0.079	3.89IlePhe: 3.89 ± 0.071	4.886IleGly: 4.886 ± 0.074	1.241IleHis: 1.241 ± 0.032	5.578IleIle: 5.578 ± 0.092	5.637IleLys: 5.637 ± 0.078	7.285IleLeu: 7.285 ± 0.12	1.344IleMet: 1.344 ± 0.035	4.356IleAsn: 4.356 ± 0.063	3.278IlePro: 3.278 ± 0.057	2.488IleGln: 2.488 ± 0.051	2.62IleArg: 2.62 ± 0.052	5.877IleSer: 5.877 ± 0.078	4.228IleThr: 4.228 ± 0.075	4.114IleVal: 4.114 ± 0.068	0.669IleTrp: 0.669 ± 0.022	2.838IleTyr: 2.838 ± 0.053	0.0IleXaa: 0.0 ± 0.0
Lys	5.026LysAla: 5.026 ± 0.077	0.327LysCys: 0.327 ± 0.016	4.64LysAsp: 4.64 ± 0.072	6.932LysGlu: 6.932 ± 0.098	3.187LysPhe: 3.187 ± 0.055	4.136LysGly: 4.136 ± 0.064	1.405LysHis: 1.405 ± 0.035	6.232LysIle: 6.232 ± 0.082	6.853LysLys: 6.853 ± 0.114	6.879LysLeu: 6.879 ± 0.092	2.049LysMet: 2.049 ± 0.048	5.218LysAsn: 5.218 ± 0.078	2.549LysPro: 2.549 ± 0.051	2.468LysGln: 2.468 ± 0.058	3.018LysArg: 3.018 ± 0.054	4.43LysSer: 4.43 ± 0.068	4.223LysThr: 4.223 ± 0.07	4.463LysVal: 4.463 ± 0.066	0.754LysTrp: 0.754 ± 0.027	2.856LysTyr: 2.856 ± 0.054	0.0LysXaa: 0.0 ± 0.0
Leu	5.993LeuAla: 5.993 ± 0.085	0.579LeuCys: 0.579 ± 0.024	5.319LeuAsp: 5.319 ± 0.088	7.214LeuGlu: 7.214 ± 0.086	4.777LeuPhe: 4.777 ± 0.082	5.937LeuGly: 5.937 ± 0.092	1.507LeuHis: 1.507 ± 0.038	7.0LeuIle: 7.0 ± 0.105	8.049LeuLys: 8.049 ± 0.094	8.77LeuLeu: 8.77 ± 0.128	2.066LeuMet: 2.066 ± 0.051	5.581LeuAsn: 5.581 ± 0.089	3.651LeuPro: 3.651 ± 0.056	3.476LeuGln: 3.476 ± 0.072	3.383LeuArg: 3.383 ± 0.058	6.557LeuSer: 6.557 ± 0.079	4.588LeuThr: 4.588 ± 0.064	5.354LeuVal: 5.354 ± 0.074	0.85LeuTrp: 0.85 ± 0.029	3.058LeuTyr: 3.058 ± 0.067	0.0LeuXaa: 0.0 ± 0.0
Met	1.697MetAla: 1.697 ± 0.043	0.109MetCys: 0.109 ± 0.009	1.237MetAsp: 1.237 ± 0.034	1.683MetGlu: 1.683 ± 0.041	0.833MetPhe: 0.833 ± 0.032	1.504MetGly: 1.504 ± 0.04	0.386MetHis: 0.386 ± 0.018	1.417MetIle: 1.417 ± 0.046	2.212MetLys: 2.212 ± 0.044	2.065MetLeu: 2.065 ± 0.049	0.611MetMet: 0.611 ± 0.027	1.232MetAsn: 1.232 ± 0.033	0.85MetPro: 0.85 ± 0.027	0.924MetGln: 0.924 ± 0.033	0.917MetArg: 0.917 ± 0.023	1.267MetSer: 1.267 ± 0.032	0.949MetThr: 0.949 ± 0.031	1.365MetVal: 1.365 ± 0.034	0.173MetTrp: 0.173 ± 0.012	0.643MetTyr: 0.643 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.62AsnAla: 3.62 ± 0.056	0.42AsnCys: 0.42 ± 0.033	2.829AsnAsp: 2.829 ± 0.059	3.953AsnGlu: 3.953 ± 0.054	3.374AsnPhe: 3.374 ± 0.065	3.627AsnGly: 3.627 ± 0.085	1.002AsnHis: 1.002 ± 0.035	4.663AsnIle: 4.663 ± 0.075	4.134AsnLys: 4.134 ± 0.078	5.726AsnLeu: 5.726 ± 0.09	1.22AsnMet: 1.22 ± 0.033	3.512AsnAsn: 3.512 ± 0.077	2.759AsnPro: 2.759 ± 0.057	2.14AsnGln: 2.14 ± 0.048	2.333AsnArg: 2.333 ± 0.05	3.893AsnSer: 3.893 ± 0.071	3.31AsnThr: 3.31 ± 0.06	3.102AsnVal: 3.102 ± 0.056	0.782AsnTrp: 0.782 ± 0.029	2.791AsnTyr: 2.791 ± 0.062	0.0AsnXaa: 0.0 ± 0.0
Pro	2.089ProAla: 2.089 ± 0.054	0.179ProCys: 0.179 ± 0.011	2.163ProAsp: 2.163 ± 0.044	3.656ProGlu: 3.656 ± 0.066	1.797ProPhe: 1.797 ± 0.04	2.348ProGly: 2.348 ± 0.056	0.603ProHis: 0.603 ± 0.024	2.468ProIle: 2.468 ± 0.039	2.545ProLys: 2.545 ± 0.054	3.017ProLeu: 3.017 ± 0.061	0.672ProMet: 0.672 ± 0.025	1.99ProAsn: 1.99 ± 0.045	0.847ProPro: 0.847 ± 0.029	1.304ProGln: 1.304 ± 0.038	1.028ProArg: 1.028 ± 0.033	2.023ProSer: 2.023 ± 0.052	1.742ProThr: 1.742 ± 0.039	2.625ProVal: 2.625 ± 0.062	0.337ProTrp: 0.337 ± 0.019	1.369ProTyr: 1.369 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	2.121GlnAla: 2.121 ± 0.049	0.13GlnCys: 0.13 ± 0.012	1.792GlnAsp: 1.792 ± 0.045	2.849GlnGlu: 2.849 ± 0.059	1.618GlnPhe: 1.618 ± 0.041	1.81GlnGly: 1.81 ± 0.039	0.606GlnHis: 0.606 ± 0.024	2.533GlnIle: 2.533 ± 0.047	2.884GlnLys: 2.884 ± 0.054	3.492GlnLeu: 3.492 ± 0.052	0.833GlnMet: 0.833 ± 0.028	2.261GlnAsn: 2.261 ± 0.055	1.137GlnPro: 1.137 ± 0.04	1.668GlnGln: 1.668 ± 0.05	1.433GlnArg: 1.433 ± 0.037	1.774GlnSer: 1.774 ± 0.042	1.755GlnThr: 1.755 ± 0.046	1.978GlnVal: 1.978 ± 0.045	0.349GlnTrp: 0.349 ± 0.017	1.236GlnTyr: 1.236 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	2.194ArgAla: 2.194 ± 0.046	0.19ArgCys: 0.19 ± 0.012	2.016ArgAsp: 2.016 ± 0.046	2.987ArgGlu: 2.987 ± 0.051	2.11ArgPhe: 2.11 ± 0.046	2.125ArgGly: 2.125 ± 0.046	0.647ArgHis: 0.647 ± 0.029	3.012ArgIle: 3.012 ± 0.056	3.235ArgLys: 3.235 ± 0.062	3.385ArgLeu: 3.385 ± 0.068	0.911ArgMet: 0.911 ± 0.029	2.374ArgAsn: 2.374 ± 0.05	1.153ArgPro: 1.153 ± 0.032	1.232ArgGln: 1.232 ± 0.038	1.49ArgArg: 1.49 ± 0.041	2.117ArgSer: 2.117 ± 0.049	1.786ArgThr: 1.786 ± 0.045	2.148ArgVal: 2.148 ± 0.05	0.415ArgTrp: 0.415 ± 0.019	1.558ArgTyr: 1.558 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	4.007SerAla: 4.007 ± 0.069	0.569SerCys: 0.569 ± 0.022	3.219SerAsp: 3.219 ± 0.064	4.958SerGlu: 4.958 ± 0.073	3.712SerPhe: 3.712 ± 0.054	4.754SerGly: 4.754 ± 0.084	1.042SerHis: 1.042 ± 0.034	4.85SerIle: 4.85 ± 0.075	4.566SerLys: 4.566 ± 0.07	6.328SerLeu: 6.328 ± 0.089	1.23SerMet: 1.23 ± 0.035	3.393SerAsn: 3.393 ± 0.065	2.084SerPro: 2.084 ± 0.048	2.068SerGln: 2.068 ± 0.039	2.472SerArg: 2.472 ± 0.059	4.063SerSer: 4.063 ± 0.066	3.166SerThr: 3.166 ± 0.054	3.875SerVal: 3.875 ± 0.063	0.694SerTrp: 0.694 ± 0.028	2.593SerTyr: 2.593 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	3.719ThrAla: 3.719 ± 0.073	0.328ThrCys: 0.328 ± 0.027	2.928ThrAsp: 2.928 ± 0.074	3.858ThrGlu: 3.858 ± 0.068	2.568ThrPhe: 2.568 ± 0.05	4.197ThrGly: 4.197 ± 0.065	0.951ThrHis: 0.951 ± 0.028	3.747ThrIle: 3.747 ± 0.079	3.283ThrLys: 3.283 ± 0.061	4.562ThrLeu: 4.562 ± 0.07	0.869ThrMet: 0.869 ± 0.028	2.804ThrAsn: 2.804 ± 0.06	2.277ThrPro: 2.277 ± 0.05	1.767ThrGln: 1.767 ± 0.044	1.833ThrArg: 1.833 ± 0.045	3.597ThrSer: 3.597 ± 0.071	2.951ThrThr: 2.951 ± 0.078	3.198ThrVal: 3.198 ± 0.084	0.553ThrTrp: 0.553 ± 0.023	2.176ThrTyr: 2.176 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	4.032ValAla: 4.032 ± 0.06	0.448ValCys: 0.448 ± 0.023	3.399ValAsp: 3.399 ± 0.05	4.314ValGlu: 4.314 ± 0.075	3.121ValPhe: 3.121 ± 0.052	3.643ValGly: 3.643 ± 0.06	0.916ValHis: 0.916 ± 0.03	4.694ValIle: 4.694 ± 0.075	4.216ValLys: 4.216 ± 0.07	5.695ValLeu: 5.695 ± 0.087	1.387ValMet: 1.387 ± 0.037	3.355ValAsn: 3.355 ± 0.061	2.199ValPro: 2.199 ± 0.047	1.838ValGln: 1.838 ± 0.044	1.999ValArg: 1.999 ± 0.045	4.23ValSer: 4.23 ± 0.057	3.161ValThr: 3.161 ± 0.087	3.854ValVal: 3.854 ± 0.082	0.545ValTrp: 0.545 ± 0.026	2.167ValTyr: 2.167 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.629TrpAla: 0.629 ± 0.022	0.079TrpCys: 0.079 ± 0.007	0.632TrpAsp: 0.632 ± 0.024	0.809TrpGlu: 0.809 ± 0.03	0.615TrpPhe: 0.615 ± 0.022	0.635TrpGly: 0.635 ± 0.023	0.224TrpHis: 0.224 ± 0.014	0.72TrpIle: 0.72 ± 0.028	0.792TrpLys: 0.792 ± 0.031	1.029TrpLeu: 1.029 ± 0.031	0.309TrpMet: 0.309 ± 0.016	0.659TrpAsn: 0.659 ± 0.023	0.304TrpPro: 0.304 ± 0.017	0.396TrpGln: 0.396 ± 0.02	0.44TrpArg: 0.44 ± 0.02	0.597TrpSer: 0.597 ± 0.026	0.477TrpThr: 0.477 ± 0.026	0.607TrpVal: 0.607 ± 0.022	0.165TrpTrp: 0.165 ± 0.012	0.445TrpTyr: 0.445 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.275TyrAla: 2.275 ± 0.049	0.264TyrCys: 0.264 ± 0.015	2.162TyrAsp: 2.162 ± 0.048	2.579TyrGlu: 2.579 ± 0.053	2.503TyrPhe: 2.503 ± 0.058	2.588TyrGly: 2.588 ± 0.051	0.773TyrHis: 0.773 ± 0.027	2.506TyrIle: 2.506 ± 0.046	2.926TyrLys: 2.926 ± 0.062	3.905TyrLeu: 3.905 ± 0.063	0.727TyrMet: 0.727 ± 0.025	2.319TyrAsn: 2.319 ± 0.044	1.475TyrPro: 1.475 ± 0.036	1.551TyrGln: 1.551 ± 0.035	1.736TyrArg: 1.736 ± 0.044	2.641TyrSer: 2.641 ± 0.063	2.2TyrThr: 2.2 ± 0.047	1.986TyrVal: 1.986 ± 0.043	0.484TyrTrp: 0.484 ± 0.023	1.772TyrTyr: 1.772 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3284 proteins (1108007 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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