Amino acid dipepetide frequency for Meleagris gallopavo (Wild turkey)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.134AlaAla: 6.134 ± 0.042	1.355AlaCys: 1.355 ± 0.017	3.059AlaAsp: 3.059 ± 0.018	4.886AlaGlu: 4.886 ± 0.031	2.605AlaPhe: 2.605 ± 0.024	4.104AlaGly: 4.104 ± 0.03	1.387AlaHis: 1.387 ± 0.012	3.005AlaIle: 3.005 ± 0.022	3.701AlaLys: 3.701 ± 0.027	6.532AlaLeu: 6.532 ± 0.035	1.507AlaMet: 1.507 ± 0.016	2.227AlaAsn: 2.227 ± 0.018	3.127AlaPro: 3.127 ± 0.028	2.871AlaGln: 2.871 ± 0.024	3.052AlaArg: 3.052 ± 0.023	5.316AlaSer: 5.316 ± 0.031	3.334AlaThr: 3.334 ± 0.024	5.04AlaVal: 5.04 ± 0.027	0.714AlaTrp: 0.714 ± 0.01	1.595AlaTyr: 1.595 ± 0.015	0.012AlaXaa: 0.012 ± 0.001
Cys	1.235CysAla: 1.235 ± 0.016	0.688CysCys: 0.688 ± 0.012	1.07CysAsp: 1.07 ± 0.016	1.333CysGlu: 1.333 ± 0.02	0.957CysPhe: 0.957 ± 0.011	1.49CysGly: 1.49 ± 0.021	0.675CysHis: 0.675 ± 0.011	1.153CysIle: 1.153 ± 0.015	1.344CysLys: 1.344 ± 0.015	2.187CysLeu: 2.187 ± 0.021	0.469CysMet: 0.469 ± 0.008	0.928CysAsn: 0.928 ± 0.012	1.305CysPro: 1.305 ± 0.019	1.115CysGln: 1.115 ± 0.016	1.305CysArg: 1.305 ± 0.017	2.182CysSer: 2.182 ± 0.022	1.233CysThr: 1.233 ± 0.014	1.359CysVal: 1.359 ± 0.015	0.311CysTrp: 0.311 ± 0.007	0.67CysTyr: 0.67 ± 0.009	0.004CysXaa: 0.004 ± 0.001
Asp	2.96AspAla: 2.96 ± 0.02	1.105AspCys: 1.105 ± 0.014	2.801AspAsp: 2.801 ± 0.023	3.671AspGlu: 3.671 ± 0.028	2.217AspPhe: 2.217 ± 0.017	3.342AspGly: 3.342 ± 0.025	1.107AspHis: 1.107 ± 0.012	2.874AspIle: 2.874 ± 0.021	2.748AspLys: 2.748 ± 0.025	4.941AspLeu: 4.941 ± 0.025	1.132AspMet: 1.132 ± 0.011	1.91AspAsn: 1.91 ± 0.02	2.608AspPro: 2.608 ± 0.021	1.803AspGln: 1.803 ± 0.014	2.351AspArg: 2.351 ± 0.022	4.185AspSer: 4.185 ± 0.027	2.489AspThr: 2.489 ± 0.017	3.254AspVal: 3.254 ± 0.02	0.623AspTrp: 0.623 ± 0.009	1.595AspTyr: 1.595 ± 0.014	0.005AspXaa: 0.005 ± 0.001
Glu	4.765GluAla: 4.765 ± 0.033	1.361GluCys: 1.361 ± 0.02	4.511GluAsp: 4.511 ± 0.027	7.977GluGlu: 7.977 ± 0.066	2.167GluPhe: 2.167 ± 0.018	3.926GluGly: 3.926 ± 0.027	1.574GluHis: 1.574 ± 0.015	3.511GluIle: 3.511 ± 0.023	5.753GluLys: 5.753 ± 0.049	6.533GluLeu: 6.533 ± 0.045	1.812GluMet: 1.812 ± 0.015	3.466GluAsn: 3.466 ± 0.024	2.715GluPro: 2.715 ± 0.025	3.313GluGln: 3.313 ± 0.025	3.98GluArg: 3.98 ± 0.034	4.534GluSer: 4.534 ± 0.028	3.514GluThr: 3.514 ± 0.024	4.31GluVal: 4.31 ± 0.028	0.743GluTrp: 0.743 ± 0.011	1.799GluTyr: 1.799 ± 0.016	0.008GluXaa: 0.008 ± 0.001
Phe	2.115PheAla: 2.115 ± 0.016	1.017PheCys: 1.017 ± 0.012	1.797PheAsp: 1.797 ± 0.016	2.108PheGlu: 2.108 ± 0.019	1.739PhePhe: 1.739 ± 0.02	2.268PheGly: 2.268 ± 0.016	1.094PheHis: 1.094 ± 0.012	2.044PheIle: 2.044 ± 0.018	1.975PheLys: 1.975 ± 0.016	4.161PheLeu: 4.161 ± 0.03	0.764PheMet: 0.764 ± 0.01	1.475PheAsn: 1.475 ± 0.014	1.971PhePro: 1.971 ± 0.017	1.855PheGln: 1.855 ± 0.015	1.893PheArg: 1.893 ± 0.016	3.514PheSer: 3.514 ± 0.024	2.158PheThr: 2.158 ± 0.019	2.331PheVal: 2.331 ± 0.018	0.506PheTrp: 0.506 ± 0.008	1.294PheTyr: 1.294 ± 0.014	0.004PheXaa: 0.004 ± 0.001
Gly	3.635GlyAla: 3.635 ± 0.027	1.295GlyCys: 1.295 ± 0.018	3.002GlyAsp: 3.002 ± 0.027	3.894GlyGlu: 3.894 ± 0.039	2.414GlyPhe: 2.414 ± 0.02	4.022GlyGly: 4.022 ± 0.046	1.509GlyHis: 1.509 ± 0.015	3.023GlyIle: 3.023 ± 0.025	3.879GlyLys: 3.879 ± 0.029	5.21GlyLeu: 5.21 ± 0.035	1.391GlyMet: 1.391 ± 0.014	2.564GlyAsn: 2.564 ± 0.022	2.963GlyPro: 2.963 ± 0.063	2.546GlyGln: 2.546 ± 0.023	3.254GlyArg: 3.254 ± 0.024	5.308GlySer: 5.308 ± 0.035	3.539GlyThr: 3.539 ± 0.026	3.392GlyVal: 3.392 ± 0.024	0.77GlyTrp: 0.77 ± 0.011	1.852GlyTyr: 1.852 ± 0.018	0.009GlyXaa: 0.009 ± 0.001
His	1.352HisAla: 1.352 ± 0.013	0.753HisCys: 0.753 ± 0.012	0.928HisAsp: 0.928 ± 0.012	1.357HisGlu: 1.357 ± 0.013	1.079HisPhe: 1.079 ± 0.011	1.503HisGly: 1.503 ± 0.015	0.852HisHis: 0.852 ± 0.013	1.337HisIle: 1.337 ± 0.013	1.348HisLys: 1.348 ± 0.014	2.782HisLeu: 2.782 ± 0.021	0.569HisMet: 0.569 ± 0.008	0.984HisAsn: 0.984 ± 0.012	1.521HisPro: 1.521 ± 0.013	1.201HisGln: 1.201 ± 0.014	1.479HisArg: 1.479 ± 0.015	2.28HisSer: 2.28 ± 0.021	1.311HisThr: 1.311 ± 0.014	1.496HisVal: 1.496 ± 0.012	0.331HisTrp: 0.331 ± 0.006	0.877HisTyr: 0.877 ± 0.011	0.004HisXaa: 0.004 ± 0.001
Ile	2.966IleAla: 2.966 ± 0.02	1.22IleCys: 1.22 ± 0.012	2.267IleAsp: 2.267 ± 0.02	2.859IleGlu: 2.859 ± 0.025	2.109IlePhe: 2.109 ± 0.019	2.427IleGly: 2.427 ± 0.021	1.359IleHis: 1.359 ± 0.012	2.654IleIle: 2.654 ± 0.021	2.986IleLys: 2.986 ± 0.02	4.889IleLeu: 4.889 ± 0.031	1.021IleMet: 1.021 ± 0.01	2.131IleAsn: 2.131 ± 0.015	2.79IlePro: 2.79 ± 0.019	2.501IleGln: 2.501 ± 0.021	2.497IleArg: 2.497 ± 0.018	4.174IleSer: 4.174 ± 0.025	2.868IleThr: 2.868 ± 0.021	2.826IleVal: 2.826 ± 0.02	0.567IleTrp: 0.567 ± 0.009	1.571IleTyr: 1.571 ± 0.016	0.005IleXaa: 0.005 ± 0.001
Lys	4.126LysAla: 4.126 ± 0.029	1.233LysCys: 1.233 ± 0.015	3.416LysAsp: 3.416 ± 0.021	5.612LysGlu: 5.612 ± 0.043	1.869LysPhe: 1.869 ± 0.017	3.403LysGly: 3.403 ± 0.039	1.57LysHis: 1.57 ± 0.016	3.149LysIle: 3.149 ± 0.024	5.383LysLys: 5.383 ± 0.048	5.712LysLeu: 5.712 ± 0.038	1.571LysMet: 1.571 ± 0.015	2.746LysAsn: 2.746 ± 0.023	3.015LysPro: 3.015 ± 0.026	3.02LysGln: 3.02 ± 0.031	3.505LysArg: 3.505 ± 0.026	4.294LysSer: 4.294 ± 0.031	3.343LysThr: 3.343 ± 0.025	3.673LysVal: 3.673 ± 0.026	0.669LysTrp: 0.669 ± 0.01	1.838LysTyr: 1.838 ± 0.017	0.01LysXaa: 0.01 ± 0.001
Leu	6.199LeuAla: 6.199 ± 0.036	2.311LeuCys: 2.311 ± 0.022	4.693LeuAsp: 4.693 ± 0.028	7.062LeuGlu: 7.062 ± 0.045	3.534LeuPhe: 3.534 ± 0.029	5.113LeuGly: 5.113 ± 0.026	2.744LeuHis: 2.744 ± 0.023	4.176LeuIle: 4.176 ± 0.026	6.365LeuLys: 6.365 ± 0.038	10.282LeuLeu: 10.282 ± 0.056	2.004LeuMet: 2.004 ± 0.014	3.833LeuAsn: 3.833 ± 0.025	5.443LeuPro: 5.443 ± 0.032	5.859LeuGln: 5.859 ± 0.04	5.302LeuArg: 5.302 ± 0.028	8.002LeuSer: 8.002 ± 0.034	4.999LeuThr: 4.999 ± 0.022	5.316LeuVal: 5.316 ± 0.029	1.088LeuTrp: 1.088 ± 0.012	2.743LeuTyr: 2.743 ± 0.023	0.014LeuXaa: 0.014 ± 0.001
Met	1.676MetAla: 1.676 ± 0.014	0.433MetCys: 0.433 ± 0.007	1.265MetAsp: 1.265 ± 0.011	1.917MetGlu: 1.917 ± 0.016	0.805MetPhe: 0.805 ± 0.011	1.255MetGly: 1.255 ± 0.013	0.509MetHis: 0.509 ± 0.009	0.949MetIle: 0.949 ± 0.011	1.624MetLys: 1.624 ± 0.014	2.087MetLeu: 2.087 ± 0.017	0.583MetMet: 0.583 ± 0.01	0.966MetAsn: 0.966 ± 0.012	1.056MetPro: 1.056 ± 0.011	1.065MetGln: 1.065 ± 0.012	1.049MetArg: 1.049 ± 0.012	1.544MetSer: 1.544 ± 0.015	1.103MetThr: 1.103 ± 0.012	1.366MetVal: 1.366 ± 0.012	0.249MetTrp: 0.249 ± 0.006	0.627MetTyr: 0.627 ± 0.008	0.003MetXaa: 0.003 ± 0.001
Asn	2.382AsnAla: 2.382 ± 0.018	1.001AsnCys: 1.001 ± 0.015	1.694AsnAsp: 1.694 ± 0.016	2.568AsnGlu: 2.568 ± 0.021	1.615AsnPhe: 1.615 ± 0.015	2.711AsnGly: 2.711 ± 0.024	0.985AsnHis: 0.985 ± 0.011	2.464AsnIle: 2.464 ± 0.018	2.559AsnLys: 2.559 ± 0.02	3.992AsnLeu: 3.992 ± 0.028	0.978AsnMet: 0.978 ± 0.012	1.826AsnAsn: 1.826 ± 0.017	2.215AsnPro: 2.215 ± 0.018	1.713AsnGln: 1.713 ± 0.016	1.97AsnArg: 1.97 ± 0.016	3.471AsnSer: 3.471 ± 0.026	2.228AsnThr: 2.228 ± 0.019	2.488AsnVal: 2.488 ± 0.019	0.487AsnTrp: 0.487 ± 0.008	1.281AsnTyr: 1.281 ± 0.013	0.005AsnXaa: 0.005 ± 0.001
Pro	3.957ProAla: 3.957 ± 0.031	1.106ProCys: 1.106 ± 0.017	2.558ProAsp: 2.558 ± 0.018	3.895ProGlu: 3.895 ± 0.025	1.87ProPhe: 1.87 ± 0.017	4.054ProGly: 4.054 ± 0.094	1.299ProHis: 1.299 ± 0.014	1.976ProIle: 1.976 ± 0.017	2.742ProLys: 2.742 ± 0.024	4.608ProLeu: 4.608 ± 0.03	0.959ProMet: 0.959 ± 0.013	1.888ProAsn: 1.888 ± 0.016	4.538ProPro: 4.538 ± 0.063	2.414ProGln: 2.414 ± 0.02	2.581ProArg: 2.581 ± 0.02	5.054ProSer: 5.054 ± 0.039	2.765ProThr: 2.765 ± 0.02	3.663ProVal: 3.663 ± 0.025	0.572ProTrp: 0.572 ± 0.009	1.411ProTyr: 1.411 ± 0.015	0.01ProXaa: 0.01 ± 0.001
Gln	3.149GlnAla: 3.149 ± 0.025	1.011GlnCys: 1.011 ± 0.013	2.234GlnAsp: 2.234 ± 0.016	3.765GlnGlu: 3.765 ± 0.031	1.46GlnPhe: 1.46 ± 0.015	2.574GlnGly: 2.574 ± 0.028	1.359GlnHis: 1.359 ± 0.015	2.192GlnIle: 2.192 ± 0.018	3.236GlnLys: 3.236 ± 0.026	4.758GlnLeu: 4.758 ± 0.034	1.129GlnMet: 1.129 ± 0.012	2.066GlnAsn: 2.066 ± 0.017	2.487GlnPro: 2.487 ± 0.022	3.167GlnGln: 3.167 ± 0.045	2.744GlnArg: 2.744 ± 0.024	3.307GlnSer: 3.307 ± 0.024	2.366GlnThr: 2.366 ± 0.019	2.754GlnVal: 2.754 ± 0.02	0.537GlnTrp: 0.537 ± 0.008	1.271GlnTyr: 1.271 ± 0.014	0.01GlnXaa: 0.01 ± 0.001
Arg	3.283ArgAla: 3.283 ± 0.024	1.208ArgCys: 1.208 ± 0.017	2.631ArgAsp: 2.631 ± 0.023	3.744ArgGlu: 3.744 ± 0.034	1.855ArgPhe: 1.855 ± 0.016	3.063ArgGly: 3.063 ± 0.034	1.397ArgHis: 1.397 ± 0.016	2.588ArgIle: 2.588 ± 0.019	3.791ArgLys: 3.791 ± 0.027	4.861ArgLeu: 4.861 ± 0.031	1.196ArgMet: 1.196 ± 0.014	2.267ArgAsn: 2.267 ± 0.016	2.459ArgPro: 2.459 ± 0.019	2.499ArgGln: 2.499 ± 0.021	3.791ArgArg: 3.791 ± 0.033	4.14ArgSer: 4.14 ± 0.033	2.704ArgThr: 2.704 ± 0.02	2.94ArgVal: 2.94 ± 0.023	0.645ArgTrp: 0.645 ± 0.01	1.564ArgTyr: 1.564 ± 0.015	0.009ArgXaa: 0.009 ± 0.001
Ser	5.379SerAla: 5.379 ± 0.028	2.005SerCys: 2.005 ± 0.022	4.045SerAsp: 4.045 ± 0.028	5.268SerGlu: 5.268 ± 0.034	3.211SerPhe: 3.211 ± 0.022	5.087SerGly: 5.087 ± 0.027	2.07SerHis: 2.07 ± 0.017	3.653SerIle: 3.653 ± 0.022	4.518SerLys: 4.518 ± 0.032	8.004SerLeu: 8.004 ± 0.038	1.626SerMet: 1.626 ± 0.013	3.033SerAsn: 3.033 ± 0.025	5.311SerPro: 5.311 ± 0.04	3.734SerGln: 3.734 ± 0.024	4.232SerArg: 4.232 ± 0.032	9.518SerSer: 9.518 ± 0.062	4.701SerThr: 4.701 ± 0.031	5.207SerVal: 5.207 ± 0.029	0.987SerTrp: 0.987 ± 0.012	2.253SerTyr: 2.253 ± 0.022	0.013SerXaa: 0.013 ± 0.001
Thr	3.997ThrAla: 3.997 ± 0.025	1.345ThrCys: 1.345 ± 0.018	2.717ThrAsp: 2.717 ± 0.022	3.791ThrGlu: 3.791 ± 0.027	2.159ThrPhe: 2.159 ± 0.019	3.391ThrGly: 3.391 ± 0.025	1.178ThrHis: 1.178 ± 0.012	2.544ThrIle: 2.544 ± 0.019	2.88ThrLys: 2.88 ± 0.022	5.061ThrLeu: 5.061 ± 0.027	1.098ThrMet: 1.098 ± 0.012	1.969ThrAsn: 1.969 ± 0.017	3.094ThrPro: 3.094 ± 0.029	2.185ThrGln: 2.185 ± 0.017	2.306ThrArg: 2.306 ± 0.018	4.694ThrSer: 4.694 ± 0.034	2.985ThrThr: 2.985 ± 0.031	4.096ThrVal: 4.096 ± 0.028	0.679ThrTrp: 0.679 ± 0.011	1.544ThrTyr: 1.544 ± 0.015	0.007ThrXaa: 0.007 ± 0.001
Val	4.04ValAla: 4.04 ± 0.023	1.544ValCys: 1.544 ± 0.017	2.944ValAsp: 2.944 ± 0.022	3.977ValGlu: 3.977 ± 0.024	2.586ValPhe: 2.586 ± 0.019	3.302ValGly: 3.302 ± 0.023	1.561ValHis: 1.561 ± 0.013	3.174ValIle: 3.174 ± 0.022	3.75ValLys: 3.75 ± 0.029	6.426ValLeu: 6.426 ± 0.036	1.354ValMet: 1.354 ± 0.013	2.504ValAsn: 2.504 ± 0.019	3.539ValPro: 3.539 ± 0.028	2.847ValGln: 2.847 ± 0.021	2.965ValArg: 2.965 ± 0.02	5.003ValSer: 5.003 ± 0.025	3.84ValThr: 3.84 ± 0.025	4.146ValVal: 4.146 ± 0.029	0.726ValTrp: 0.726 ± 0.01	1.784ValTyr: 1.784 ± 0.017	0.008ValXaa: 0.008 ± 0.001
Trp	0.677TrpAla: 0.677 ± 0.009	0.255TrpCys: 0.255 ± 0.006	0.664TrpAsp: 0.664 ± 0.01	0.779TrpGlu: 0.779 ± 0.011	0.465TrpPhe: 0.465 ± 0.008	0.648TrpGly: 0.648 ± 0.011	0.312TrpHis: 0.312 ± 0.007	0.605TrpIle: 0.605 ± 0.01	0.883TrpLys: 0.883 ± 0.011	1.209TrpLeu: 1.209 ± 0.015	0.32TrpMet: 0.32 ± 0.007	0.571TrpAsn: 0.571 ± 0.009	0.435TrpPro: 0.435 ± 0.007	0.551TrpGln: 0.551 ± 0.009	0.667TrpArg: 0.667 ± 0.009	0.892TrpSer: 0.892 ± 0.011	0.634TrpThr: 0.634 ± 0.01	0.662TrpVal: 0.662 ± 0.009	0.196TrpTrp: 0.196 ± 0.006	0.37TrpTyr: 0.37 ± 0.008	0.002TrpXaa: 0.002 ± 0.001
Tyr	1.523TyrAla: 1.523 ± 0.014	0.763TyrCys: 0.763 ± 0.01	1.419TyrAsp: 1.419 ± 0.016	1.802TyrGlu: 1.802 ± 0.017	1.365TyrPhe: 1.365 ± 0.014	1.776TyrGly: 1.776 ± 0.017	0.801TyrHis: 0.801 ± 0.009	1.61TyrIle: 1.61 ± 0.015	1.682TyrLys: 1.682 ± 0.018	2.833TyrLeu: 2.833 ± 0.021	0.644TyrMet: 0.644 ± 0.008	1.274TyrAsn: 1.274 ± 0.012	1.317TyrPro: 1.317 ± 0.015	1.312TyrGln: 1.312 ± 0.015	1.699TyrArg: 1.699 ± 0.019	2.432TyrSer: 2.432 ± 0.019	1.602TyrThr: 1.602 ± 0.016	1.695TyrVal: 1.695 ± 0.016	0.393TyrTrp: 0.393 ± 0.01	1.074TyrTyr: 1.074 ± 0.013	0.003TyrXaa: 0.003 ± 0.001
Xaa	0.013XaaAla: 0.013 ± 0.001	0.005XaaCys: 0.005 ± 0.001	0.007XaaAsp: 0.007 ± 0.001	0.008XaaGlu: 0.008 ± 0.001	0.005XaaPhe: 0.005 ± 0.001	0.012XaaGly: 0.012 ± 0.001	0.003XaaHis: 0.003 ± 0.001	0.005XaaIle: 0.005 ± 0.001	0.01XaaLys: 0.01 ± 0.001	0.015XaaLeu: 0.015 ± 0.001	0.003XaaMet: 0.003 ± 0.001	0.004XaaAsn: 0.004 ± 0.001	0.01XaaPro: 0.01 ± 0.001	0.007XaaGln: 0.007 ± 0.001	0.011XaaArg: 0.011 ± 0.001	0.011XaaSer: 0.011 ± 0.001	0.005XaaThr: 0.005 ± 0.001	0.007XaaVal: 0.007 ± 0.001	0.002XaaTrp: 0.002 ± 0.0	0.003XaaTyr: 0.003 ± 0.001	0.16XaaXaa: 0.16 ± 0.015

Statistics based on 16533 proteins (8776270 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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