Amino acid dipepetide frequency for Streptocarpus flower break virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.747AlaAla: 5.747 ± 1.515
0.319AlaCys: 0.319 ± 0.203
1.277AlaAsp: 1.277 ± 0.268
3.831AlaGlu: 3.831 ± 0.645
2.235AlaPhe: 2.235 ± 0.623
4.47AlaGly: 4.47 ± 0.255
0.639AlaHis: 0.639 ± 0.134
2.874AlaIle: 2.874 ± 2.181
5.109AlaLys: 5.109 ± 0.652
7.663AlaLeu: 7.663 ± 0.974
3.193AlaMet: 3.193 ± 0.433
3.831AlaAsn: 3.831 ± 0.457
1.596AlaPro: 1.596 ± 0.308
1.916AlaGln: 1.916 ± 0.402
3.193AlaArg: 3.193 ± 0.566
7.663AlaSer: 7.663 ± 0.639
2.554AlaThr: 2.554 ± 0.974
6.705AlaVal: 6.705 ± 0.427
1.277AlaTrp: 1.277 ± 0.268
1.596AlaTyr: 1.596 ± 0.601
0.0AlaXaa: 0.0 ± 0.0
Cys
1.916CysAla: 1.916 ± 0.685
0.958CysCys: 0.958 ± 0.224
1.277CysAsp: 1.277 ± 0.268
1.916CysGlu: 1.916 ± 0.402
0.639CysPhe: 0.639 ± 0.134
1.277CysGly: 1.277 ± 0.406
0.0CysHis: 0.0 ± 0.0
0.319CysIle: 0.319 ± 0.203
0.958CysLys: 0.958 ± 0.224
0.319CysLeu: 0.319 ± 0.203
0.0CysMet: 0.0 ± 0.0
1.916CysAsn: 1.916 ± 0.402
0.639CysPro: 0.639 ± 0.134
0.639CysGln: 0.639 ± 0.134
0.0CysArg: 0.0 ± 0.0
1.277CysSer: 1.277 ± 0.487
0.639CysThr: 0.639 ± 0.134
0.958CysVal: 0.958 ± 0.224
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.554AspAla: 2.554 ± 1.133
0.319AspCys: 0.319 ± 0.203
0.639AspAsp: 0.639 ± 0.558
5.428AspGlu: 5.428 ± 0.375
3.512AspPhe: 3.512 ± 0.742
2.554AspGly: 2.554 ± 0.522
0.0AspHis: 0.0 ± 0.0
3.512AspIle: 3.512 ± 0.627
3.512AspLys: 3.512 ± 0.318
7.344AspLeu: 7.344 ± 0.855
1.596AspMet: 1.596 ± 0.308
2.554AspAsn: 2.554 ± 0.207
2.235AspPro: 2.235 ± 0.299
0.639AspGln: 0.639 ± 0.134
2.554AspArg: 2.554 ± 0.522
7.344AspSer: 7.344 ± 0.748
3.193AspThr: 3.193 ± 0.48
8.301AspVal: 8.301 ± 0.879
1.277AspTrp: 1.277 ± 0.268
1.916AspTyr: 1.916 ± 0.448
0.0AspXaa: 0.0 ± 0.0
Glu
4.47GluAla: 4.47 ± 0.43
0.639GluCys: 0.639 ± 0.134
1.916GluAsp: 1.916 ± 0.213
5.747GluGlu: 5.747 ± 0.924
7.344GluPhe: 7.344 ± 0.622
1.596GluGly: 1.596 ± 0.29
0.958GluHis: 0.958 ± 0.224
5.747GluIle: 5.747 ± 0.754
5.747GluLys: 5.747 ± 0.754
5.747GluLeu: 5.747 ± 0.741
0.639GluMet: 0.639 ± 0.134
1.277GluAsn: 1.277 ± 0.487
2.235GluPro: 2.235 ± 0.301
1.916GluGln: 1.916 ± 0.446
3.193GluArg: 3.193 ± 0.492
2.874GluSer: 2.874 ± 0.519
1.596GluThr: 1.596 ± 1.763
5.428GluVal: 5.428 ± 0.375
0.319GluTrp: 0.319 ± 0.424
2.554GluTyr: 2.554 ± 0.522
0.0GluXaa: 0.0 ± 0.0
Phe
2.554PheAla: 2.554 ± 0.207
2.235PheCys: 2.235 ± 0.623
2.874PheAsp: 2.874 ± 0.439
2.554PheGlu: 2.554 ± 0.492
3.512PhePhe: 3.512 ± 0.668
2.235PheGly: 2.235 ± 0.451
2.874PheHis: 2.874 ± 0.541
2.554PheIle: 2.554 ± 0.522
1.916PheLys: 1.916 ± 0.213
4.47PheLeu: 4.47 ± 0.597
0.958PheMet: 0.958 ± 0.216
0.958PheAsn: 0.958 ± 0.224
3.512PhePro: 3.512 ± 0.636
2.235PheGln: 2.235 ± 1.239
2.874PheArg: 2.874 ± 0.672
4.789PheSer: 4.789 ± 0.82
1.916PheThr: 1.916 ± 0.402
5.428PheVal: 5.428 ± 1.12
0.319PheTrp: 0.319 ± 0.203
1.596PheTyr: 1.596 ± 0.308
0.0PheXaa: 0.0 ± 0.0
Gly
2.235GlyAla: 2.235 ± 0.451
1.916GlyCys: 1.916 ± 0.213
2.554GlyAsp: 2.554 ± 0.464
3.193GlyGlu: 3.193 ± 0.275
1.596GlyPhe: 1.596 ± 1.076
3.512GlyGly: 3.512 ± 1.342
0.958GlyHis: 0.958 ± 0.224
1.916GlyIle: 1.916 ± 0.685
7.024GlyLys: 7.024 ± 0.918
2.874GlyLeu: 2.874 ± 0.519
1.596GlyMet: 1.596 ± 0.308
4.47GlyAsn: 4.47 ± 0.514
0.319GlyPro: 0.319 ± 0.203
1.277GlyGln: 1.277 ± 0.406
1.596GlyArg: 1.596 ± 0.308
4.151GlySer: 4.151 ± 0.308
3.193GlyThr: 3.193 ± 0.925
3.193GlyVal: 3.193 ± 0.275
0.0GlyTrp: 0.0 ± 0.0
1.596GlyTyr: 1.596 ± 0.501
0.0GlyXaa: 0.0 ± 0.0
His
0.639HisAla: 0.639 ± 0.134
1.596HisCys: 1.596 ± 0.308
0.319HisAsp: 0.319 ± 0.203
1.277HisGlu: 1.277 ± 0.268
1.277HisPhe: 1.277 ± 0.268
2.554HisGly: 2.554 ± 0.537
0.958HisHis: 0.958 ± 0.224
0.958HisIle: 0.958 ± 0.224
1.596HisLys: 1.596 ± 0.29
2.235HisLeu: 2.235 ± 0.42
1.277HisMet: 1.277 ± 0.406
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.958HisGln: 0.958 ± 0.338
0.319HisArg: 0.319 ± 0.203
2.235HisSer: 2.235 ± 0.42
2.554HisThr: 2.554 ± 0.537
1.916HisVal: 1.916 ± 0.402
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.639IleAla: 0.639 ± 0.406
0.0IleCys: 0.0 ± 0.0
3.193IleAsp: 3.193 ± 0.74
0.958IleGlu: 0.958 ± 0.609
0.639IlePhe: 0.639 ± 0.558
2.874IleGly: 2.874 ± 0.672
1.596IleHis: 1.596 ± 0.308
3.831IleIle: 3.831 ± 0.895
4.151IleLys: 4.151 ± 1.066
8.301IleLeu: 8.301 ± 0.816
0.639IleMet: 0.639 ± 0.134
2.554IleAsn: 2.554 ± 0.444
2.874IlePro: 2.874 ± 0.364
1.277IleGln: 1.277 ± 0.406
2.235IleArg: 2.235 ± 0.532
4.47IleSer: 4.47 ± 0.996
1.916IleThr: 1.916 ± 0.402
2.874IleVal: 2.874 ± 0.972
0.319IleTrp: 0.319 ± 0.203
1.596IleTyr: 1.596 ± 0.308
0.0IleXaa: 0.0 ± 0.0
Lys
6.066LysAla: 6.066 ± 0.613
0.639LysCys: 0.639 ± 0.134
4.47LysAsp: 4.47 ± 0.839
4.151LysGlu: 4.151 ± 0.797
3.831LysPhe: 3.831 ± 0.427
4.151LysGly: 4.151 ± 0.789
0.639LysHis: 0.639 ± 0.406
3.512LysIle: 3.512 ± 0.668
1.277LysLys: 1.277 ± 0.268
6.066LysLeu: 6.066 ± 0.796
1.596LysMet: 1.596 ± 0.376
3.512LysAsn: 3.512 ± 0.404
3.193LysPro: 3.193 ± 0.566
0.958LysGln: 0.958 ± 0.609
5.428LysArg: 5.428 ± 0.666
2.235LysSer: 2.235 ± 0.725
4.789LysThr: 4.789 ± 0.664
5.747LysVal: 5.747 ± 0.728
0.639LysTrp: 0.639 ± 0.134
2.874LysTyr: 2.874 ± 0.519
0.0LysXaa: 0.0 ± 0.0
Leu
9.259LeuAla: 9.259 ± 1.749
0.319LeuCys: 0.319 ± 0.609
5.109LeuAsp: 5.109 ± 1.044
9.259LeuGlu: 9.259 ± 0.872
4.789LeuPhe: 4.789 ± 0.664
1.596LeuGly: 1.596 ± 0.37
2.235LeuHis: 2.235 ± 0.301
3.831LeuIle: 3.831 ± 0.381
5.428LeuLys: 5.428 ± 1.29
8.301LeuLeu: 8.301 ± 0.536
0.958LeuMet: 0.958 ± 0.224
7.024LeuAsn: 7.024 ± 0.672
4.151LeuPro: 4.151 ± 0.809
4.47LeuGln: 4.47 ± 0.581
6.066LeuArg: 6.066 ± 0.819
9.259LeuSer: 9.259 ± 0.61
5.747LeuThr: 5.747 ± 0.64
8.621LeuVal: 8.621 ± 0.869
1.596LeuTrp: 1.596 ± 1.08
0.639LeuTyr: 0.639 ± 0.134
0.0LeuXaa: 0.0 ± 0.0
Met
0.958MetAla: 0.958 ± 0.338
0.639MetCys: 0.639 ± 0.134
2.235MetAsp: 2.235 ± 0.623
0.0MetGlu: 0.0 ± 0.0
0.319MetPhe: 0.319 ± 0.203
0.958MetGly: 0.958 ± 0.338
0.0MetHis: 0.0 ± 0.0
1.277MetIle: 1.277 ± 0.406
1.277MetLys: 1.277 ± 0.268
2.235MetLeu: 2.235 ± 0.42
0.958MetMet: 0.958 ± 0.553
1.916MetAsn: 1.916 ± 1.106
0.0MetPro: 0.0 ± 0.0
0.639MetGln: 0.639 ± 0.134
0.319MetArg: 0.319 ± 0.203
0.639MetSer: 0.639 ± 0.134
1.277MetThr: 1.277 ± 0.268
2.554MetVal: 2.554 ± 0.522
0.319MetTrp: 0.319 ± 0.203
0.958MetTyr: 0.958 ± 0.338
0.0MetXaa: 0.0 ± 0.0
Asn
3.831AsnAla: 3.831 ± 0.535
0.319AsnCys: 0.319 ± 0.203
3.193AsnAsp: 3.193 ± 0.48
0.958AsnGlu: 0.958 ± 0.224
4.47AsnPhe: 4.47 ± 0.963
1.277AsnGly: 1.277 ± 0.29
0.639AsnHis: 0.639 ± 0.134
0.0AsnIle: 0.0 ± 0.0
1.596AsnLys: 1.596 ± 0.29
6.386AsnLeu: 6.386 ± 0.696
0.639AsnMet: 0.639 ± 0.134
3.193AsnAsn: 3.193 ± 0.925
1.277AsnPro: 1.277 ± 0.268
1.916AsnGln: 1.916 ± 0.402
3.193AsnArg: 3.193 ± 1.769
3.512AsnSer: 3.512 ± 1.361
3.831AsnThr: 3.831 ± 0.548
4.151AsnVal: 4.151 ± 1.258
0.958AsnTrp: 0.958 ± 0.338
3.193AsnTyr: 3.193 ± 0.275
0.0AsnXaa: 0.0 ± 0.0
Pro
3.193ProAla: 3.193 ± 0.617
0.0ProCys: 0.0 ± 0.0
2.235ProAsp: 2.235 ± 0.299
2.554ProGlu: 2.554 ± 0.492
0.639ProPhe: 0.639 ± 0.134
1.596ProGly: 1.596 ± 0.308
0.639ProHis: 0.639 ± 0.134
0.0ProIle: 0.0 ± 0.0
5.109ProLys: 5.109 ± 0.413
4.151ProLeu: 4.151 ± 0.386
0.958ProMet: 0.958 ± 0.609
1.277ProAsn: 1.277 ± 0.755
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
1.916ProArg: 1.916 ± 0.448
2.874ProSer: 2.874 ± 0.439
3.831ProThr: 3.831 ± 0.381
3.512ProVal: 3.512 ± 0.318
0.319ProTrp: 0.319 ± 0.424
1.916ProTyr: 1.916 ± 0.402
0.0ProXaa: 0.0 ± 0.0
Gln
1.596GlnAla: 1.596 ± 0.526
0.0GlnCys: 0.0 ± 0.0
2.554GlnAsp: 2.554 ± 0.522
0.958GlnGlu: 0.958 ± 0.338
1.596GlnPhe: 1.596 ± 0.649
0.958GlnGly: 0.958 ± 0.224
0.0GlnHis: 0.0 ± 0.0
2.235GlnIle: 2.235 ± 0.725
0.319GlnLys: 0.319 ± 0.203
3.831GlnLeu: 3.831 ± 0.895
0.639GlnMet: 0.639 ± 0.33
2.554GlnAsn: 2.554 ± 0.537
1.277GlnPro: 1.277 ± 0.29
1.916GlnGln: 1.916 ± 0.402
2.235GlnArg: 2.235 ± 1.022
3.512GlnSer: 3.512 ± 0.459
3.193GlnThr: 3.193 ± 0.924
1.596GlnVal: 1.596 ± 1.076
0.0GlnTrp: 0.0 ± 0.0
1.277GlnTyr: 1.277 ± 0.268
0.319GlnXaa: 0.319 ± 0.203
Arg
4.47ArgAla: 4.47 ± 0.601
1.277ArgCys: 1.277 ± 0.268
3.831ArgAsp: 3.831 ± 0.675
1.596ArgGlu: 1.596 ± 1.076
1.277ArgPhe: 1.277 ± 1.098
4.47ArgGly: 4.47 ± 1.094
1.596ArgHis: 1.596 ± 0.29
1.596ArgIle: 1.596 ± 0.501
2.874ArgLys: 2.874 ± 0.672
5.428ArgLeu: 5.428 ± 0.883
0.319ArgMet: 0.319 ± 0.424
2.554ArgAsn: 2.554 ± 0.207
1.596ArgPro: 1.596 ± 0.649
0.319ArgGln: 0.319 ± 0.203
1.916ArgArg: 1.916 ± 0.213
2.874ArgSer: 2.874 ± 0.571
5.428ArgThr: 5.428 ± 0.747
5.109ArgVal: 5.109 ± 0.74
0.319ArgTrp: 0.319 ± 0.203
1.277ArgTyr: 1.277 ± 0.29
0.0ArgXaa: 0.0 ± 0.0
Ser
4.47SerAla: 4.47 ± 0.946
0.639SerCys: 0.639 ± 0.134
5.428SerAsp: 5.428 ± 0.408
7.024SerGlu: 7.024 ± 0.767
6.066SerPhe: 6.066 ± 0.778
5.428SerGly: 5.428 ± 1.259
3.831SerHis: 3.831 ± 0.805
4.47SerIle: 4.47 ± 0.398
4.151SerLys: 4.151 ± 1.204
7.344SerLeu: 7.344 ± 0.511
0.958SerMet: 0.958 ± 0.224
3.512SerAsn: 3.512 ± 0.318
1.596SerPro: 1.596 ± 0.29
2.874SerGln: 2.874 ± 0.8
1.596SerArg: 1.596 ± 0.691
3.193SerSer: 3.193 ± 0.617
3.193SerThr: 3.193 ± 1.061
8.621SerVal: 8.621 ± 0.867
0.0SerTrp: 0.0 ± 0.0
0.958SerTyr: 0.958 ± 0.224
0.0SerXaa: 0.0 ± 0.0
Thr
5.109ThrAla: 5.109 ± 1.407
1.916ThrCys: 1.916 ± 0.402
2.554ThrAsp: 2.554 ± 0.207
1.596ThrGlu: 1.596 ± 0.526
4.789ThrPhe: 4.789 ± 0.927
2.235ThrGly: 2.235 ± 0.42
1.277ThrHis: 1.277 ± 0.268
3.512ThrIle: 3.512 ± 0.656
6.705ThrLys: 6.705 ± 0.769
6.066ThrLeu: 6.066 ± 0.327
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
3.193ThrPro: 3.193 ± 0.617
3.831ThrGln: 3.831 ± 1.527
3.831ThrArg: 3.831 ± 1.193
1.916ThrSer: 1.916 ± 0.611
2.235ThrThr: 2.235 ± 1.162
4.151ThrVal: 4.151 ± 0.402
0.639ThrTrp: 0.639 ± 0.134
3.512ThrTyr: 3.512 ± 0.459
0.0ThrXaa: 0.0 ± 0.0
Val
6.386ValAla: 6.386 ± 0.978
1.916ValCys: 1.916 ± 0.213
9.898ValAsp: 9.898 ± 1.306
6.066ValGlu: 6.066 ± 0.613
1.596ValPhe: 1.596 ± 0.308
2.554ValGly: 2.554 ± 1.509
2.874ValHis: 2.874 ± 0.541
4.151ValIle: 4.151 ± 0.827
3.512ValLys: 3.512 ± 0.459
7.344ValLeu: 7.344 ± 0.543
1.277ValMet: 1.277 ± 0.268
4.47ValAsn: 4.47 ± 0.5
5.109ValPro: 5.109 ± 0.84
1.596ValGln: 1.596 ± 0.29
5.747ValArg: 5.747 ± 0.52
8.301ValSer: 8.301 ± 2.125
4.789ValThr: 4.789 ± 0.414
7.024ValVal: 7.024 ± 2.535
0.958ValTrp: 0.958 ± 0.224
5.747ValTyr: 5.747 ± 0.741
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.277TrpAsp: 1.277 ± 0.268
1.596TrpGlu: 1.596 ± 0.501
1.277TrpPhe: 1.277 ± 0.268
0.639TrpGly: 0.639 ± 0.134
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.319TrpLys: 0.319 ± 0.203
1.277TrpLeu: 1.277 ± 0.29
0.0TrpMet: 0.0 ± 0.0
0.319TrpAsn: 0.319 ± 0.203
0.0TrpPro: 0.0 ± 0.0
0.958TrpGln: 0.958 ± 0.338
0.319TrpArg: 0.319 ± 0.424
0.319TrpSer: 0.319 ± 0.609
0.639TrpThr: 0.639 ± 0.134
0.639TrpVal: 0.639 ± 0.134
0.0TrpTrp: 0.0 ± 0.0
0.319TrpTyr: 0.319 ± 0.203
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.596TyrAla: 1.596 ± 0.308
0.0TyrCys: 0.0 ± 0.0
4.151TyrAsp: 4.151 ± 0.827
1.277TyrGlu: 1.277 ± 0.268
0.958TyrPhe: 0.958 ± 0.47
2.235TyrGly: 2.235 ± 0.42
0.958TyrHis: 0.958 ± 0.224
0.639TyrIle: 0.639 ± 0.558
3.193TyrLys: 3.193 ± 0.617
1.277TyrLeu: 1.277 ± 0.406
0.958TyrMet: 0.958 ± 0.553
0.639TyrAsn: 0.639 ± 0.848
1.916TyrPro: 1.916 ± 0.448
2.235TyrGln: 2.235 ± 0.42
1.596TyrArg: 1.596 ± 0.29
1.916TyrSer: 1.916 ± 0.402
2.554TyrThr: 2.554 ± 0.522
4.789TyrVal: 4.789 ± 0.474
0.639TyrTrp: 0.639 ± 0.134
1.277TyrTyr: 1.277 ± 0.406
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.319XaaGln: 0.319 ± 0.203
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3133 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski