Amino acid dipepetide frequency for Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.304AlaAla: 16.304 ± 0.242	1.16AlaCys: 1.16 ± 0.045	7.069AlaAsp: 7.069 ± 0.12	10.066AlaGlu: 10.066 ± 0.159	3.714AlaPhe: 3.714 ± 0.07	11.034AlaGly: 11.034 ± 0.134	2.444AlaHis: 2.444 ± 0.06	4.538AlaIle: 4.538 ± 0.102	1.785AlaLys: 1.785 ± 0.052	13.796AlaLeu: 13.796 ± 0.171	2.516AlaMet: 2.516 ± 0.062	1.96AlaAsn: 1.96 ± 0.046	5.331AlaPro: 5.331 ± 0.094	4.182AlaGln: 4.182 ± 0.071	9.528AlaArg: 9.528 ± 0.138	4.832AlaSer: 4.832 ± 0.074	5.278AlaThr: 5.278 ± 0.085	9.573AlaVal: 9.573 ± 0.128	1.878AlaTrp: 1.878 ± 0.052	2.692AlaTyr: 2.692 ± 0.061	0.0AlaXaa: 0.0 ± 0.0
Cys	1.005CysAla: 1.005 ± 0.037	0.123CysCys: 0.123 ± 0.011	0.52CysAsp: 0.52 ± 0.027	0.5CysGlu: 0.5 ± 0.025	0.276CysPhe: 0.276 ± 0.019	0.938CysGly: 0.938 ± 0.032	0.355CysHis: 0.355 ± 0.027	0.313CysIle: 0.313 ± 0.022	0.159CysLys: 0.159 ± 0.017	0.825CysLeu: 0.825 ± 0.032	0.139CysMet: 0.139 ± 0.013	0.203CysAsn: 0.203 ± 0.016	0.599CysPro: 0.599 ± 0.03	0.353CysGln: 0.353 ± 0.021	0.857CysArg: 0.857 ± 0.038	0.45CysSer: 0.45 ± 0.023	0.466CysThr: 0.466 ± 0.027	0.593CysVal: 0.593 ± 0.028	0.134CysTrp: 0.134 ± 0.012	0.248CysTyr: 0.248 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	7.098AspAla: 7.098 ± 0.103	0.523AspCys: 0.523 ± 0.027	4.103AspAsp: 4.103 ± 0.095	4.876AspGlu: 4.876 ± 0.092	1.965AspPhe: 1.965 ± 0.051	5.828AspGly: 5.828 ± 0.101	1.525AspHis: 1.525 ± 0.044	2.143AspIle: 2.143 ± 0.054	0.89AspLys: 0.89 ± 0.043	6.289AspLeu: 6.289 ± 0.108	1.024AspMet: 1.024 ± 0.035	1.162AspAsn: 1.162 ± 0.04	4.419AspPro: 4.419 ± 0.073	2.112AspGln: 2.112 ± 0.052	5.024AspArg: 5.024 ± 0.097	2.285AspSer: 2.285 ± 0.056	2.791AspThr: 2.791 ± 0.056	3.802AspVal: 3.802 ± 0.079	1.09AspTrp: 1.09 ± 0.039	1.706AspTyr: 1.706 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	10.175GluAla: 10.175 ± 0.14	0.456GluCys: 0.456 ± 0.025	3.98GluAsp: 3.98 ± 0.091	5.192GluGlu: 5.192 ± 0.112	1.536GluPhe: 1.536 ± 0.051	5.69GluGly: 5.69 ± 0.091	2.113GluHis: 2.113 ± 0.049	3.064GluIle: 3.064 ± 0.066	1.263GluLys: 1.263 ± 0.045	7.754GluLeu: 7.754 ± 0.118	1.444GluMet: 1.444 ± 0.04	1.297GluAsn: 1.297 ± 0.04	4.04GluPro: 4.04 ± 0.098	4.275GluGln: 4.275 ± 0.077	8.291GluArg: 8.291 ± 0.12	3.041GluSer: 3.041 ± 0.068	3.557GluThr: 3.557 ± 0.074	5.502GluVal: 5.502 ± 0.089	0.916GluTrp: 0.916 ± 0.034	1.298GluTyr: 1.298 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	3.265PheAla: 3.265 ± 0.065	0.314PheCys: 0.314 ± 0.021	2.062PheAsp: 2.062 ± 0.052	2.279PheGlu: 2.279 ± 0.054	1.146PhePhe: 1.146 ± 0.047	2.85PheGly: 2.85 ± 0.078	0.777PheHis: 0.777 ± 0.029	1.27PheIle: 1.27 ± 0.043	0.563PheLys: 0.563 ± 0.027	3.123PheLeu: 3.123 ± 0.077	0.62PheMet: 0.62 ± 0.032	0.807PheAsn: 0.807 ± 0.028	1.388PhePro: 1.388 ± 0.047	1.02PheGln: 1.02 ± 0.036	2.35PheArg: 2.35 ± 0.057	1.704PheSer: 1.704 ± 0.053	1.707PheThr: 1.707 ± 0.054	2.022PheVal: 2.022 ± 0.054	0.441PheTrp: 0.441 ± 0.025	0.858PheTyr: 0.858 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	9.35GlyAla: 9.35 ± 0.123	1.055GlyCys: 1.055 ± 0.038	5.278GlyAsp: 5.278 ± 0.096	6.427GlyGlu: 6.427 ± 0.109	3.088GlyPhe: 3.088 ± 0.066	8.074GlyGly: 8.074 ± 0.141	2.19GlyHis: 2.19 ± 0.056	3.83GlyIle: 3.83 ± 0.078	1.88GlyLys: 1.88 ± 0.053	9.268GlyLeu: 9.268 ± 0.122	2.172GlyMet: 2.172 ± 0.055	1.715GlyAsn: 1.715 ± 0.051	3.714GlyPro: 3.714 ± 0.073	3.371GlyGln: 3.371 ± 0.07	7.173GlyArg: 7.173 ± 0.119	4.302GlySer: 4.302 ± 0.075	4.414GlyThr: 4.414 ± 0.082	7.417GlyVal: 7.417 ± 0.111	1.569GlyTrp: 1.569 ± 0.052	2.623GlyTyr: 2.623 ± 0.059	0.0GlyXaa: 0.0 ± 0.0
His	2.561HisAla: 2.561 ± 0.061	0.313HisCys: 0.313 ± 0.022	1.408HisAsp: 1.408 ± 0.048	1.484HisGlu: 1.484 ± 0.044	0.799HisPhe: 0.799 ± 0.031	2.383HisGly: 2.383 ± 0.058	0.797HisHis: 0.797 ± 0.035	0.914HisIle: 0.914 ± 0.032	0.395HisLys: 0.395 ± 0.021	2.615HisLeu: 2.615 ± 0.061	0.406HisMet: 0.406 ± 0.023	0.516HisAsn: 0.516 ± 0.028	1.795HisPro: 1.795 ± 0.047	0.982HisGln: 0.982 ± 0.036	2.336HisArg: 2.336 ± 0.057	1.01HisSer: 1.01 ± 0.037	1.158HisThr: 1.158 ± 0.037	1.427HisVal: 1.427 ± 0.038	0.445HisTrp: 0.445 ± 0.022	0.754HisTyr: 0.754 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	4.863IleAla: 4.863 ± 0.081	0.352IleCys: 0.352 ± 0.021	3.223IleAsp: 3.223 ± 0.069	3.334IleGlu: 3.334 ± 0.063	1.141IlePhe: 1.141 ± 0.04	3.981IleGly: 3.981 ± 0.072	1.173IleHis: 1.173 ± 0.037	1.462IleIle: 1.462 ± 0.056	0.885IleLys: 0.885 ± 0.037	3.741IleLeu: 3.741 ± 0.078	0.618IleMet: 0.618 ± 0.027	1.141IleAsn: 1.141 ± 0.036	2.22IlePro: 2.22 ± 0.057	1.365IleGln: 1.365 ± 0.044	3.322IleArg: 3.322 ± 0.074	1.948IleSer: 1.948 ± 0.056	2.166IleThr: 2.166 ± 0.053	2.615IleVal: 2.615 ± 0.069	0.423IleTrp: 0.423 ± 0.026	0.966IleTyr: 0.966 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	2.07LysAla: 2.07 ± 0.062	0.112LysCys: 0.112 ± 0.014	0.925LysAsp: 0.925 ± 0.037	1.134LysGlu: 1.134 ± 0.042	0.4LysPhe: 0.4 ± 0.026	1.521LysGly: 1.521 ± 0.053	0.397LysHis: 0.397 ± 0.022	0.771LysIle: 0.771 ± 0.037	0.59LysLys: 0.59 ± 0.041	1.641LysLeu: 1.641 ± 0.05	0.358LysMet: 0.358 ± 0.023	0.452LysAsn: 0.452 ± 0.029	0.995LysPro: 0.995 ± 0.037	0.743LysGln: 0.743 ± 0.031	1.76LysArg: 1.76 ± 0.047	0.914LysSer: 0.914 ± 0.036	0.95LysThr: 0.95 ± 0.038	1.293LysVal: 1.293 ± 0.047	0.178LysTrp: 0.178 ± 0.016	0.396LysTyr: 0.396 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	13.439LeuAla: 13.439 ± 0.172	0.933LeuCys: 0.933 ± 0.034	6.928LeuAsp: 6.928 ± 0.1	8.52LeuGlu: 8.52 ± 0.097	3.352LeuPhe: 3.352 ± 0.082	9.221LeuGly: 9.221 ± 0.12	2.6LeuHis: 2.6 ± 0.06	4.595LeuIle: 4.595 ± 0.078	1.859LeuLys: 1.859 ± 0.047	11.082LeuLeu: 11.082 ± 0.163	2.013LeuMet: 2.013 ± 0.052	2.248LeuAsn: 2.248 ± 0.053	5.944LeuPro: 5.944 ± 0.093	3.828LeuGln: 3.828 ± 0.073	9.202LeuArg: 9.202 ± 0.117	5.238LeuSer: 5.238 ± 0.08	5.22LeuThr: 5.22 ± 0.079	7.434LeuVal: 7.434 ± 0.107	1.191LeuTrp: 1.191 ± 0.043	2.347LeuTyr: 2.347 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.592MetAla: 2.592 ± 0.063	0.098MetCys: 0.098 ± 0.01	1.204MetAsp: 1.204 ± 0.039	1.365MetGlu: 1.365 ± 0.038	0.428MetPhe: 0.428 ± 0.022	1.64MetGly: 1.64 ± 0.049	0.446MetHis: 0.446 ± 0.02	0.838MetIle: 0.838 ± 0.032	0.49MetLys: 0.49 ± 0.025	1.896MetLeu: 1.896 ± 0.049	0.403MetMet: 0.403 ± 0.023	0.53MetAsn: 0.53 ± 0.025	1.122MetPro: 1.122 ± 0.037	0.74MetGln: 0.74 ± 0.035	1.651MetArg: 1.651 ± 0.048	1.25MetSer: 1.25 ± 0.037	1.269MetThr: 1.269 ± 0.036	1.412MetVal: 1.412 ± 0.044	0.152MetTrp: 0.152 ± 0.014	0.303MetTyr: 0.303 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.262AsnAla: 2.262 ± 0.054	0.189AsnCys: 0.189 ± 0.017	1.086AsnAsp: 1.086 ± 0.039	1.239AsnGlu: 1.239 ± 0.043	0.609AsnPhe: 0.609 ± 0.029	1.608AsnGly: 1.608 ± 0.056	0.472AsnHis: 0.472 ± 0.025	0.951AsnIle: 0.951 ± 0.038	0.422AsnLys: 0.422 ± 0.023	2.269AsnLeu: 2.269 ± 0.056	0.395AsnMet: 0.395 ± 0.021	0.494AsnAsn: 0.494 ± 0.024	1.504AsnPro: 1.504 ± 0.045	0.733AsnGln: 0.733 ± 0.032	1.858AsnArg: 1.858 ± 0.05	0.773AsnSer: 0.773 ± 0.037	1.032AsnThr: 1.032 ± 0.035	1.437AsnVal: 1.437 ± 0.042	0.304AsnTrp: 0.304 ± 0.02	0.462AsnTyr: 0.462 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	6.283ProAla: 6.283 ± 0.111	0.392ProCys: 0.392 ± 0.024	3.656ProAsp: 3.656 ± 0.062	5.407ProGlu: 5.407 ± 0.119	1.646ProPhe: 1.646 ± 0.045	5.381ProGly: 5.381 ± 0.096	1.062ProHis: 1.062 ± 0.038	1.846ProIle: 1.846 ± 0.048	0.894ProLys: 0.894 ± 0.038	5.171ProLeu: 5.171 ± 0.09	1.073ProMet: 1.073 ± 0.037	0.965ProAsn: 0.965 ± 0.032	3.015ProPro: 3.015 ± 0.073	1.95ProGln: 1.95 ± 0.048	3.891ProArg: 3.891 ± 0.067	2.39ProSer: 2.39 ± 0.058	2.391ProThr: 2.391 ± 0.057	4.3ProVal: 4.3 ± 0.07	0.901ProTrp: 0.901 ± 0.038	1.193ProTyr: 1.193 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	5.086GlnAla: 5.086 ± 0.08	0.272GlnCys: 0.272 ± 0.018	1.763GlnAsp: 1.763 ± 0.046	2.677GlnGlu: 2.677 ± 0.062	0.919GlnPhe: 0.919 ± 0.034	3.208GlnGly: 3.208 ± 0.071	0.851GlnHis: 0.851 ± 0.035	1.605GlnIle: 1.605 ± 0.048	0.642GlnLys: 0.642 ± 0.031	4.067GlnLeu: 4.067 ± 0.077	0.766GlnMet: 0.766 ± 0.029	0.563GlnAsn: 0.563 ± 0.03	2.23GlnPro: 2.23 ± 0.057	1.937GlnGln: 1.937 ± 0.065	4.442GlnArg: 4.442 ± 0.078	1.52GlnSer: 1.52 ± 0.048	1.715GlnThr: 1.715 ± 0.051	3.042GlnVal: 3.042 ± 0.067	0.579GlnTrp: 0.579 ± 0.025	0.711GlnTyr: 0.711 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	8.879ArgAla: 8.879 ± 0.126	0.792ArgCys: 0.792 ± 0.033	4.852ArgAsp: 4.852 ± 0.074	6.28ArgGlu: 6.28 ± 0.105	3.16ArgPhe: 3.16 ± 0.064	6.488ArgGly: 6.488 ± 0.094	2.433ArgHis: 2.433 ± 0.056	4.285ArgIle: 4.285 ± 0.077	1.587ArgLys: 1.587 ± 0.051	10.367ArgLeu: 10.367 ± 0.137	1.973ArgMet: 1.973 ± 0.047	1.759ArgAsn: 1.759 ± 0.053	4.257ArgPro: 4.257 ± 0.085	3.639ArgGln: 3.639 ± 0.071	8.377ArgArg: 8.377 ± 0.13	3.946ArgSer: 3.946 ± 0.078	3.653ArgThr: 3.653 ± 0.069	6.47ArgVal: 6.47 ± 0.111	1.451ArgTrp: 1.451 ± 0.045	2.438ArgTyr: 2.438 ± 0.057	0.0ArgXaa: 0.0 ± 0.0
Ser	5.334SerAla: 5.334 ± 0.085	0.397SerCys: 0.397 ± 0.022	2.655SerAsp: 2.655 ± 0.063	3.068SerGlu: 3.068 ± 0.076	1.374SerPhe: 1.374 ± 0.046	5.159SerGly: 5.159 ± 0.086	1.035SerHis: 1.035 ± 0.036	1.747SerIle: 1.747 ± 0.053	0.825SerLys: 0.825 ± 0.035	4.613SerLeu: 4.613 ± 0.074	1.073SerMet: 1.073 ± 0.035	0.966SerAsn: 0.966 ± 0.039	2.312SerPro: 2.312 ± 0.053	1.467SerGln: 1.467 ± 0.044	3.626SerArg: 3.626 ± 0.068	2.293SerSer: 2.293 ± 0.07	2.139SerThr: 2.139 ± 0.054	3.527SerVal: 3.527 ± 0.067	0.561SerTrp: 0.561 ± 0.028	1.039SerTyr: 1.039 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.713ThrAla: 5.713 ± 0.09	0.42ThrCys: 0.42 ± 0.023	2.856ThrAsp: 2.856 ± 0.058	3.262ThrGlu: 3.262 ± 0.068	1.476ThrPhe: 1.476 ± 0.048	4.82ThrGly: 4.82 ± 0.083	1.014ThrHis: 1.014 ± 0.036	1.859ThrIle: 1.859 ± 0.056	0.706ThrLys: 0.706 ± 0.034	5.957ThrLeu: 5.957 ± 0.088	0.733ThrMet: 0.733 ± 0.033	0.911ThrAsn: 0.911 ± 0.032	3.258ThrPro: 3.258 ± 0.061	1.446ThrGln: 1.446 ± 0.05	3.55ThrArg: 3.55 ± 0.069	2.018ThrSer: 2.018 ± 0.053	2.308ThrThr: 2.308 ± 0.055	4.133ThrVal: 4.133 ± 0.076	0.591ThrTrp: 0.591 ± 0.029	1.071ThrTyr: 1.071 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	9.568ValAla: 9.568 ± 0.132	0.749ValCys: 0.749 ± 0.028	4.896ValAsp: 4.896 ± 0.081	5.543ValGlu: 5.543 ± 0.085	2.311ValPhe: 2.311 ± 0.06	5.98ValGly: 5.98 ± 0.099	1.813ValHis: 1.813 ± 0.043	3.379ValIle: 3.379 ± 0.076	1.202ValLys: 1.202 ± 0.047	7.85ValLeu: 7.85 ± 0.119	1.402ValMet: 1.402 ± 0.037	1.579ValAsn: 1.579 ± 0.042	3.669ValPro: 3.669 ± 0.075	2.493ValGln: 2.493 ± 0.05	6.052ValArg: 6.052 ± 0.091	3.524ValSer: 3.524 ± 0.072	4.062ValThr: 4.062 ± 0.069	6.57ValVal: 6.57 ± 0.115	0.857ValTrp: 0.857 ± 0.034	1.677ValTyr: 1.677 ± 0.054	0.0ValXaa: 0.0 ± 0.0
Trp	1.336TrpAla: 1.336 ± 0.043	0.132TrpCys: 0.132 ± 0.011	0.734TrpAsp: 0.734 ± 0.036	0.807TrpGlu: 0.807 ± 0.034	0.381TrpPhe: 0.381 ± 0.026	0.979TrpGly: 0.979 ± 0.04	0.354TrpHis: 0.354 ± 0.02	0.658TrpIle: 0.658 ± 0.028	0.194TrpLys: 0.194 ± 0.014	2.151TrpLeu: 2.151 ± 0.06	0.314TrpMet: 0.314 ± 0.022	0.277TrpAsn: 0.277 ± 0.017	0.71TrpPro: 0.71 ± 0.034	0.895TrpGln: 0.895 ± 0.036	1.314TrpArg: 1.314 ± 0.044	0.732TrpSer: 0.732 ± 0.032	0.621TrpThr: 0.621 ± 0.031	1.134TrpVal: 1.134 ± 0.038	0.257TrpTrp: 0.257 ± 0.018	0.358TrpTyr: 0.358 ± 0.024	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.494TyrAla: 2.494 ± 0.059	0.273TyrCys: 0.273 ± 0.02	1.459TyrAsp: 1.459 ± 0.045	1.426TyrGlu: 1.426 ± 0.048	0.845TyrPhe: 0.845 ± 0.03	2.127TyrGly: 2.127 ± 0.048	0.647TyrHis: 0.647 ± 0.027	0.868TyrIle: 0.868 ± 0.033	0.37TyrLys: 0.37 ± 0.024	2.72TyrLeu: 2.72 ± 0.055	0.389TyrMet: 0.389 ± 0.023	0.555TyrAsn: 0.555 ± 0.03	1.287TyrPro: 1.287 ± 0.037	1.06TyrGln: 1.06 ± 0.037	2.483TyrArg: 2.483 ± 0.062	1.039TyrSer: 1.039 ± 0.04	1.204TyrThr: 1.204 ± 0.041	1.472TyrVal: 1.472 ± 0.05	0.422TyrTrp: 0.422 ± 0.021	0.636TyrTyr: 0.636 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2406 proteins (815824 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---