Amino acid dipepetide frequency for Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.081AlaAla: 6.081 ± 0.034	1.21AlaCys: 1.21 ± 0.01	2.649AlaAsp: 2.649 ± 0.013	4.413AlaGlu: 4.413 ± 0.021	2.633AlaPhe: 2.633 ± 0.016	4.181AlaGly: 4.181 ± 0.023	1.39AlaHis: 1.39 ± 0.01	2.825AlaIle: 2.825 ± 0.014	3.399AlaLys: 3.399 ± 0.021	6.533AlaLeu: 6.533 ± 0.026	1.393AlaMet: 1.393 ± 0.008	2.019AlaAsn: 2.019 ± 0.01	3.749AlaPro: 3.749 ± 0.025	2.984AlaGln: 2.984 ± 0.016	3.216AlaArg: 3.216 ± 0.018	5.38AlaSer: 5.38 ± 0.02	3.254AlaThr: 3.254 ± 0.018	4.203AlaVal: 4.203 ± 0.018	0.696AlaTrp: 0.696 ± 0.006	1.428AlaTyr: 1.428 ± 0.01	0.0AlaXaa: 0.0 ± 0.0
Cys	1.08CysAla: 1.08 ± 0.01	0.581CysCys: 0.581 ± 0.008	0.982CysAsp: 0.982 ± 0.01	1.237CysGlu: 1.237 ± 0.01	0.822CysPhe: 0.822 ± 0.007	1.768CysGly: 1.768 ± 0.021	0.624CysHis: 0.624 ± 0.006	0.999CysIle: 0.999 ± 0.009	1.185CysLys: 1.185 ± 0.008	2.071CysLeu: 2.071 ± 0.012	0.413CysMet: 0.413 ± 0.005	1.025CysAsn: 1.025 ± 0.014	1.297CysPro: 1.297 ± 0.012	1.033CysGln: 1.033 ± 0.01	1.138CysArg: 1.138 ± 0.009	1.917CysSer: 1.917 ± 0.012	1.048CysThr: 1.048 ± 0.009	1.189CysVal: 1.189 ± 0.01	0.269CysTrp: 0.269 ± 0.004	0.563CysTyr: 0.563 ± 0.005	0.0CysXaa: 0.0 ± 0.0
Asp	2.577AspAla: 2.577 ± 0.012	1.009AspCys: 1.009 ± 0.01	2.649AspAsp: 2.649 ± 0.015	3.492AspGlu: 3.492 ± 0.016	2.162AspPhe: 2.162 ± 0.009	3.184AspGly: 3.184 ± 0.022	1.166AspHis: 1.166 ± 0.01	2.762AspIle: 2.762 ± 0.019	2.638AspLys: 2.638 ± 0.015	5.036AspLeu: 5.036 ± 0.022	1.139AspMet: 1.139 ± 0.008	1.82AspAsn: 1.82 ± 0.011	2.806AspPro: 2.806 ± 0.013	1.875AspGln: 1.875 ± 0.01	2.344AspArg: 2.344 ± 0.014	4.268AspSer: 4.268 ± 0.024	2.384AspThr: 2.384 ± 0.012	2.98AspVal: 2.98 ± 0.037	0.607AspTrp: 0.607 ± 0.006	1.507AspTyr: 1.507 ± 0.011	0.0AspXaa: 0.0 ± 0.0
Glu	4.857GluAla: 4.857 ± 0.02	1.573GluCys: 1.573 ± 0.02	4.381GluAsp: 4.381 ± 0.019	8.292GluGlu: 8.292 ± 0.045	2.087GluPhe: 2.087 ± 0.012	4.174GluGly: 4.174 ± 0.024	1.514GluHis: 1.514 ± 0.009	3.54GluIle: 3.54 ± 0.017	6.093GluLys: 6.093 ± 0.031	6.569GluLeu: 6.569 ± 0.031	1.792GluMet: 1.792 ± 0.012	3.475GluAsn: 3.475 ± 0.017	3.082GluPro: 3.082 ± 0.017	3.232GluGln: 3.232 ± 0.022	4.06GluArg: 4.06 ± 0.023	4.683GluSer: 4.683 ± 0.02	3.525GluThr: 3.525 ± 0.015	4.107GluVal: 4.107 ± 0.016	0.698GluTrp: 0.698 ± 0.007	1.624GluTyr: 1.624 ± 0.011	0.0GluXaa: 0.0 ± 0.0
Phe	1.873PheAla: 1.873 ± 0.011	0.933PheCys: 0.933 ± 0.007	1.707PheAsp: 1.707 ± 0.01	2.053PheGlu: 2.053 ± 0.013	1.71PhePhe: 1.71 ± 0.013	2.208PheGly: 2.208 ± 0.014	1.057PheHis: 1.057 ± 0.007	2.012PheIle: 2.012 ± 0.012	1.914PheLys: 1.914 ± 0.014	4.21PheLeu: 4.21 ± 0.021	0.786PheMet: 0.786 ± 0.006	1.437PheAsn: 1.437 ± 0.008	2.075PhePro: 2.075 ± 0.011	1.816PheGln: 1.816 ± 0.011	1.953PheArg: 1.953 ± 0.013	3.589PheSer: 3.589 ± 0.013	2.106PheThr: 2.106 ± 0.012	2.1PheVal: 2.1 ± 0.01	0.483PheTrp: 0.483 ± 0.006	1.208PheTyr: 1.208 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	4.035GlyAla: 4.035 ± 0.022	1.146GlyCys: 1.146 ± 0.009	3.046GlyAsp: 3.046 ± 0.016	4.323GlyGlu: 4.323 ± 0.025	2.389GlyPhe: 2.389 ± 0.015	5.05GlyGly: 5.05 ± 0.035	1.597GlyHis: 1.597 ± 0.01	2.886GlyIle: 2.886 ± 0.014	4.1GlyLys: 4.1 ± 0.022	5.525GlyLeu: 5.525 ± 0.021	1.278GlyMet: 1.278 ± 0.01	2.504GlyAsn: 2.504 ± 0.013	4.067GlyPro: 4.067 ± 0.046	2.642GlyGln: 2.642 ± 0.014	3.623GlyArg: 3.623 ± 0.017	5.652GlySer: 5.652 ± 0.027	3.471GlyThr: 3.471 ± 0.019	3.278GlyVal: 3.278 ± 0.017	0.738GlyTrp: 0.738 ± 0.007	1.698GlyTyr: 1.698 ± 0.013	0.0GlyXaa: 0.0 ± 0.0
His	1.196HisAla: 1.196 ± 0.007	0.688HisCys: 0.688 ± 0.006	0.888HisAsp: 0.888 ± 0.006	1.335HisGlu: 1.335 ± 0.008	1.083HisPhe: 1.083 ± 0.008	1.46HisGly: 1.46 ± 0.01	0.908HisHis: 0.908 ± 0.009	1.322HisIle: 1.322 ± 0.008	1.347HisLys: 1.347 ± 0.008	2.886HisLeu: 2.886 ± 0.013	0.567HisMet: 0.567 ± 0.005	0.916HisAsn: 0.916 ± 0.006	1.577HisPro: 1.577 ± 0.01	1.559HisGln: 1.559 ± 0.018	1.509HisArg: 1.509 ± 0.009	2.275HisSer: 2.275 ± 0.013	1.576HisThr: 1.576 ± 0.015	1.371HisVal: 1.371 ± 0.008	0.327HisTrp: 0.327 ± 0.004	0.814HisTyr: 0.814 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	2.616IleAla: 2.616 ± 0.013	1.131IleCys: 1.131 ± 0.009	2.179IleAsp: 2.179 ± 0.012	2.865IleGlu: 2.865 ± 0.015	2.026IlePhe: 2.026 ± 0.012	2.335IleGly: 2.335 ± 0.012	1.621IleHis: 1.621 ± 0.015	2.69IleIle: 2.69 ± 0.017	2.921IleLys: 2.921 ± 0.017	4.933IleLeu: 4.933 ± 0.02	1.071IleMet: 1.071 ± 0.008	2.024IleAsn: 2.024 ± 0.012	2.839IlePro: 2.839 ± 0.013	2.509IleGln: 2.509 ± 0.012	2.506IleArg: 2.506 ± 0.012	4.083IleSer: 4.083 ± 0.017	2.776IleThr: 2.776 ± 0.015	2.59IleVal: 2.59 ± 0.013	0.533IleTrp: 0.533 ± 0.006	1.48IleTyr: 1.48 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	4.069LysAla: 4.069 ± 0.019	1.221LysCys: 1.221 ± 0.011	3.343LysAsp: 3.343 ± 0.017	5.652LysGlu: 5.652 ± 0.03	1.816LysPhe: 1.816 ± 0.014	3.455LysGly: 3.455 ± 0.033	1.472LysHis: 1.472 ± 0.01	3.168LysIle: 3.168 ± 0.017	5.206LysLys: 5.206 ± 0.027	5.492LysLeu: 5.492 ± 0.022	1.588LysMet: 1.588 ± 0.015	2.723LysAsn: 2.723 ± 0.014	3.281LysPro: 3.281 ± 0.021	2.782LysGln: 2.782 ± 0.015	3.374LysArg: 3.374 ± 0.015	4.309LysSer: 4.309 ± 0.021	3.369LysThr: 3.369 ± 0.017	3.575LysVal: 3.575 ± 0.021	0.626LysTrp: 0.626 ± 0.005	1.628LysTyr: 1.628 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	6.244LeuAla: 6.244 ± 0.025	2.036LeuCys: 2.036 ± 0.011	4.678LeuAsp: 4.678 ± 0.021	7.334LeuGlu: 7.334 ± 0.032	3.432LeuPhe: 3.432 ± 0.018	5.667LeuGly: 5.667 ± 0.022	2.716LeuHis: 2.716 ± 0.013	4.206LeuIle: 4.206 ± 0.018	6.25LeuLys: 6.25 ± 0.03	10.441LeuLeu: 10.441 ± 0.043	2.079LeuMet: 2.079 ± 0.013	3.787LeuAsn: 3.787 ± 0.016	5.913LeuPro: 5.913 ± 0.025	5.709LeuGln: 5.709 ± 0.031	5.52LeuArg: 5.52 ± 0.023	8.241LeuSer: 8.241 ± 0.028	5.112LeuThr: 5.112 ± 0.019	5.26LeuVal: 5.26 ± 0.021	1.092LeuTrp: 1.092 ± 0.009	2.557LeuTyr: 2.557 ± 0.012	0.0LeuXaa: 0.0 ± 0.0
Met	1.789MetAla: 1.789 ± 0.01	0.394MetCys: 0.394 ± 0.004	1.288MetAsp: 1.288 ± 0.009	1.976MetGlu: 1.976 ± 0.011	0.767MetPhe: 0.767 ± 0.007	1.27MetGly: 1.27 ± 0.01	0.466MetHis: 0.466 ± 0.005	0.94MetIle: 0.94 ± 0.007	1.563MetLys: 1.563 ± 0.009	1.99MetLeu: 1.99 ± 0.011	0.592MetMet: 0.592 ± 0.006	0.991MetAsn: 0.991 ± 0.007	1.071MetPro: 1.071 ± 0.021	0.937MetGln: 0.937 ± 0.008	1.003MetArg: 1.003 ± 0.007	1.61MetSer: 1.61 ± 0.01	1.163MetThr: 1.163 ± 0.008	1.357MetVal: 1.357 ± 0.009	0.231MetTrp: 0.231 ± 0.003	0.622MetTyr: 0.622 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.035AsnAla: 2.035 ± 0.012	0.865AsnCys: 0.865 ± 0.008	1.665AsnAsp: 1.665 ± 0.01	2.594AsnGlu: 2.594 ± 0.014	1.61AsnPhe: 1.61 ± 0.009	2.559AsnGly: 2.559 ± 0.017	1.039AsnHis: 1.039 ± 0.007	2.347AsnIle: 2.347 ± 0.013	2.498AsnLys: 2.498 ± 0.013	4.079AsnLeu: 4.079 ± 0.018	0.954AsnMet: 0.954 ± 0.007	1.739AsnAsn: 1.739 ± 0.011	2.261AsnPro: 2.261 ± 0.012	1.924AsnGln: 1.924 ± 0.011	1.918AsnArg: 1.918 ± 0.01	3.447AsnSer: 3.447 ± 0.017	2.059AsnThr: 2.059 ± 0.012	2.275AsnVal: 2.275 ± 0.011	0.486AsnTrp: 0.486 ± 0.005	1.216AsnTyr: 1.216 ± 0.008	0.0AsnXaa: 0.0 ± 0.0
Pro	4.29ProAla: 4.29 ± 0.023	1.063ProCys: 1.063 ± 0.01	2.749ProAsp: 2.749 ± 0.027	4.376ProGlu: 4.376 ± 0.023	2.052ProPhe: 2.052 ± 0.012	4.912ProGly: 4.912 ± 0.048	1.382ProHis: 1.382 ± 0.009	2.049ProIle: 2.049 ± 0.011	3.021ProLys: 3.021 ± 0.044	5.171ProLeu: 5.171 ± 0.019	1.06ProMet: 1.06 ± 0.008	1.963ProAsn: 1.963 ± 0.011	6.032ProPro: 6.032 ± 0.044	2.711ProGln: 2.711 ± 0.015	3.159ProArg: 3.159 ± 0.018	5.743ProSer: 5.743 ± 0.026	3.005ProThr: 3.005 ± 0.015	3.581ProVal: 3.581 ± 0.016	0.659ProTrp: 0.659 ± 0.006	1.569ProTyr: 1.569 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	3.245GlnAla: 3.245 ± 0.019	1.031GlnCys: 1.031 ± 0.013	2.288GlnAsp: 2.288 ± 0.012	4.013GlnGlu: 4.013 ± 0.021	1.407GlnPhe: 1.407 ± 0.009	2.714GlnGly: 2.714 ± 0.015	1.288GlnHis: 1.288 ± 0.009	2.179GlnIle: 2.179 ± 0.01	3.194GlnLys: 3.194 ± 0.019	4.777GlnLeu: 4.777 ± 0.025	1.138GlnMet: 1.138 ± 0.008	2.033GlnAsn: 2.033 ± 0.013	2.648GlnPro: 2.648 ± 0.017	3.226GlnGln: 3.226 ± 0.029	2.947GlnArg: 2.947 ± 0.019	3.272GlnSer: 3.272 ± 0.017	2.334GlnThr: 2.334 ± 0.013	2.719GlnVal: 2.719 ± 0.011	0.529GlnTrp: 0.529 ± 0.005	1.175GlnTyr: 1.175 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	3.44ArgAla: 3.44 ± 0.019	1.106ArgCys: 1.106 ± 0.01	2.646ArgAsp: 2.646 ± 0.015	3.985ArgGlu: 3.985 ± 0.022	1.832ArgPhe: 1.832 ± 0.01	3.438ArgGly: 3.438 ± 0.02	1.441ArgHis: 1.441 ± 0.009	2.657ArgIle: 2.657 ± 0.015	3.725ArgLys: 3.725 ± 0.016	5.083ArgLeu: 5.083 ± 0.021	1.147ArgMet: 1.147 ± 0.008	2.168ArgAsn: 2.168 ± 0.011	2.982ArgPro: 2.982 ± 0.015	2.544ArgGln: 2.544 ± 0.014	4.116ArgArg: 4.116 ± 0.027	4.213ArgSer: 4.213 ± 0.031	2.757ArgThr: 2.757 ± 0.016	2.832ArgVal: 2.832 ± 0.013	0.639ArgTrp: 0.639 ± 0.006	1.433ArgTyr: 1.433 ± 0.008	0.0ArgXaa: 0.0 ± 0.0
Ser	4.932SerAla: 4.932 ± 0.019	1.784SerCys: 1.784 ± 0.013	3.988SerAsp: 3.988 ± 0.021	5.339SerGlu: 5.339 ± 0.02	3.199SerPhe: 3.199 ± 0.013	5.564SerGly: 5.564 ± 0.024	2.162SerHis: 2.162 ± 0.011	3.531SerIle: 3.531 ± 0.017	4.396SerLys: 4.396 ± 0.019	8.577SerLeu: 8.577 ± 0.029	1.67SerMet: 1.67 ± 0.012	2.977SerAsn: 2.977 ± 0.016	6.14SerPro: 6.14 ± 0.034	3.993SerGln: 3.993 ± 0.02	4.443SerArg: 4.443 ± 0.032	9.992SerSer: 9.992 ± 0.056	4.61SerThr: 4.61 ± 0.023	4.79SerVal: 4.79 ± 0.018	1.048SerTrp: 1.048 ± 0.007	2.144SerTyr: 2.144 ± 0.012	0.0SerXaa: 0.0 ± 0.0
Thr	3.462ThrAla: 3.462 ± 0.014	1.253ThrCys: 1.253 ± 0.013	2.507ThrAsp: 2.507 ± 0.013	3.686ThrGlu: 3.686 ± 0.015	2.256ThrPhe: 2.256 ± 0.013	3.614ThrGly: 3.614 ± 0.022	1.234ThrHis: 1.234 ± 0.011	2.589ThrIle: 2.589 ± 0.012	2.803ThrLys: 2.803 ± 0.014	5.295ThrLeu: 5.295 ± 0.021	1.14ThrMet: 1.14 ± 0.008	1.89ThrAsn: 1.89 ± 0.01	3.44ThrPro: 3.44 ± 0.021	2.238ThrGln: 2.238 ± 0.012	2.377ThrArg: 2.377 ± 0.012	4.748ThrSer: 4.748 ± 0.023	3.008ThrThr: 3.008 ± 0.021	3.715ThrVal: 3.715 ± 0.015	0.681ThrTrp: 0.681 ± 0.006	1.433ThrTyr: 1.433 ± 0.008	0.0ThrXaa: 0.0 ± 0.0
Val	3.789ValAla: 3.789 ± 0.013	1.332ValCys: 1.332 ± 0.01	2.83ValAsp: 2.83 ± 0.029	3.785ValGlu: 3.785 ± 0.016	2.291ValPhe: 2.291 ± 0.012	3.143ValGly: 3.143 ± 0.014	1.503ValHis: 1.503 ± 0.01	3.022ValIle: 3.022 ± 0.013	3.437ValLys: 3.437 ± 0.016	5.791ValLeu: 5.791 ± 0.024	1.289ValMet: 1.289 ± 0.008	2.322ValAsn: 2.322 ± 0.011	3.474ValPro: 3.474 ± 0.017	2.651ValGln: 2.651 ± 0.011	2.759ValArg: 2.759 ± 0.013	4.737ValSer: 4.737 ± 0.022	3.675ValThr: 3.675 ± 0.018	3.623ValVal: 3.623 ± 0.017	0.665ValTrp: 0.665 ± 0.006	1.577ValTyr: 1.577 ± 0.009	0.0ValXaa: 0.0 ± 0.0
Trp	0.706TrpAla: 0.706 ± 0.006	0.216TrpCys: 0.216 ± 0.003	0.632TrpAsp: 0.632 ± 0.007	0.799TrpGlu: 0.799 ± 0.007	0.423TrpPhe: 0.423 ± 0.004	0.714TrpGly: 0.714 ± 0.008	0.272TrpHis: 0.272 ± 0.004	0.578TrpIle: 0.578 ± 0.006	0.853TrpLys: 0.853 ± 0.007	1.142TrpLeu: 1.142 ± 0.009	0.313TrpMet: 0.313 ± 0.004	0.586TrpAsn: 0.586 ± 0.005	0.489TrpPro: 0.489 ± 0.005	0.505TrpGln: 0.505 ± 0.004	0.677TrpArg: 0.677 ± 0.005	0.853TrpSer: 0.853 ± 0.008	0.638TrpThr: 0.638 ± 0.007	0.634TrpVal: 0.634 ± 0.006	0.18TrpTrp: 0.18 ± 0.003	0.327TrpTyr: 0.327 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.321TyrAla: 1.321 ± 0.009	0.669TyrCys: 0.669 ± 0.006	1.31TyrAsp: 1.31 ± 0.009	1.809TyrGlu: 1.809 ± 0.013	1.233TyrPhe: 1.233 ± 0.008	1.639TyrGly: 1.639 ± 0.011	0.753TyrHis: 0.753 ± 0.005	1.426TyrIle: 1.426 ± 0.008	1.607TyrLys: 1.607 ± 0.017	2.671TyrLeu: 2.671 ± 0.014	0.61TyrMet: 0.61 ± 0.006	1.171TyrAsn: 1.171 ± 0.008	1.323TyrPro: 1.323 ± 0.009	1.286TyrGln: 1.286 ± 0.009	1.542TyrArg: 1.542 ± 0.01	2.268TyrSer: 2.268 ± 0.011	1.498TyrThr: 1.498 ± 0.01	1.518TyrVal: 1.518 ± 0.01	0.35TyrTrp: 0.35 ± 0.005	0.957TyrTyr: 0.957 ± 0.008	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.004XaaXaa: 0.004 ± 0.003

Statistics based on 36286 proteins (23604767 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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