Amino acid dipepetide frequency for Lobosporangium transversale

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.096AlaAla: 7.096 ± 0.068	0.923AlaCys: 0.923 ± 0.013	3.244AlaAsp: 3.244 ± 0.031	4.071AlaGlu: 4.071 ± 0.04	2.704AlaPhe: 2.704 ± 0.025	4.242AlaGly: 4.242 ± 0.04	1.641AlaHis: 1.641 ± 0.017	4.21AlaIle: 4.21 ± 0.034	4.033AlaLys: 4.033 ± 0.031	7.227AlaLeu: 7.227 ± 0.059	1.971AlaMet: 1.971 ± 0.02	2.942AlaAsn: 2.942 ± 0.026	3.658AlaPro: 3.658 ± 0.036	3.133AlaGln: 3.133 ± 0.033	3.685AlaArg: 3.685 ± 0.034	6.743AlaSer: 6.743 ± 0.04	5.083AlaThr: 5.083 ± 0.035	4.482AlaVal: 4.482 ± 0.034	0.779AlaTrp: 0.779 ± 0.012	1.868AlaTyr: 1.868 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	0.756CysAla: 0.756 ± 0.013	0.276CysCys: 0.276 ± 0.009	0.608CysAsp: 0.608 ± 0.011	0.617CysGlu: 0.617 ± 0.011	0.567CysPhe: 0.567 ± 0.011	0.817CysGly: 0.817 ± 0.014	0.37CysHis: 0.37 ± 0.01	0.792CysIle: 0.792 ± 0.011	0.62CysLys: 0.62 ± 0.012	1.301CysLeu: 1.301 ± 0.016	0.301CysMet: 0.301 ± 0.008	0.505CysAsn: 0.505 ± 0.009	0.716CysPro: 0.716 ± 0.014	0.499CysGln: 0.499 ± 0.012	0.701CysArg: 0.701 ± 0.012	1.031CysSer: 1.031 ± 0.014	0.682CysThr: 0.682 ± 0.013	0.73CysVal: 0.73 ± 0.012	0.169CysTrp: 0.169 ± 0.006	0.381CysTyr: 0.381 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	3.574AspAla: 3.574 ± 0.027	0.612AspCys: 0.612 ± 0.012	4.087AspAsp: 4.087 ± 0.046	4.173AspGlu: 4.173 ± 0.04	2.032AspPhe: 2.032 ± 0.02	3.353AspGly: 3.353 ± 0.026	1.46AspHis: 1.46 ± 0.019	3.379AspIle: 3.379 ± 0.024	2.609AspLys: 2.609 ± 0.023	4.944AspLeu: 4.944 ± 0.033	1.423AspMet: 1.423 ± 0.015	2.409AspAsn: 2.409 ± 0.024	2.833AspPro: 2.833 ± 0.022	2.283AspGln: 2.283 ± 0.022	2.803AspArg: 2.803 ± 0.035	4.196AspSer: 4.196 ± 0.032	2.821AspThr: 2.821 ± 0.025	3.163AspVal: 3.163 ± 0.029	0.653AspTrp: 0.653 ± 0.013	1.713AspTyr: 1.713 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	4.812GluAla: 4.812 ± 0.042	0.68GluCys: 0.68 ± 0.012	4.204GluAsp: 4.204 ± 0.042	5.622GluGlu: 5.622 ± 0.07	1.961GluPhe: 1.961 ± 0.018	3.444GluGly: 3.444 ± 0.029	1.531GluHis: 1.531 ± 0.018	3.291GluIle: 3.291 ± 0.024	3.883GluLys: 3.883 ± 0.037	5.431GluLeu: 5.431 ± 0.043	1.56GluMet: 1.56 ± 0.018	2.56GluAsn: 2.56 ± 0.024	2.34GluPro: 2.34 ± 0.022	2.975GluGln: 2.975 ± 0.028	3.605GluArg: 3.605 ± 0.037	4.446GluSer: 4.446 ± 0.037	3.241GluThr: 3.241 ± 0.026	3.182GluVal: 3.182 ± 0.03	0.7GluTrp: 0.7 ± 0.01	1.838GluTyr: 1.838 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	2.409PheAla: 2.409 ± 0.023	0.539PheCys: 0.539 ± 0.01	2.089PheAsp: 2.089 ± 0.018	2.186PheGlu: 2.186 ± 0.02	1.755PhePhe: 1.755 ± 0.026	2.524PheGly: 2.524 ± 0.028	0.918PheHis: 0.918 ± 0.014	1.94PheIle: 1.94 ± 0.021	1.933PheLys: 1.933 ± 0.02	3.511PheLeu: 3.511 ± 0.033	0.971PheMet: 0.971 ± 0.016	1.565PheAsn: 1.565 ± 0.017	1.7PhePro: 1.7 ± 0.019	1.53PheGln: 1.53 ± 0.016	1.778PheArg: 1.778 ± 0.019	3.176PheSer: 3.176 ± 0.024	2.053PheThr: 2.053 ± 0.023	2.259PheVal: 2.259 ± 0.024	0.482PheTrp: 0.482 ± 0.009	1.19PheTyr: 1.19 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	4.367GlyAla: 4.367 ± 0.035	0.783GlyCys: 0.783 ± 0.014	3.084GlyAsp: 3.084 ± 0.026	2.998GlyGlu: 2.998 ± 0.026	2.352GlyPhe: 2.352 ± 0.022	4.659GlyGly: 4.659 ± 0.047	1.72GlyHis: 1.72 ± 0.021	3.31GlyIle: 3.31 ± 0.028	3.166GlyLys: 3.166 ± 0.028	5.172GlyLeu: 5.172 ± 0.038	1.428GlyMet: 1.428 ± 0.018	2.622GlyAsn: 2.622 ± 0.024	2.623GlyPro: 2.623 ± 0.025	2.459GlyGln: 2.459 ± 0.029	3.196GlyArg: 3.196 ± 0.027	5.857GlySer: 5.857 ± 0.042	3.523GlyThr: 3.523 ± 0.029	3.621GlyVal: 3.621 ± 0.035	0.741GlyTrp: 0.741 ± 0.012	2.04GlyTyr: 2.04 ± 0.017	0.0GlyXaa: 0.0 ± 0.0
His	1.615HisAla: 1.615 ± 0.019	0.378HisCys: 0.378 ± 0.008	1.34HisAsp: 1.34 ± 0.017	1.399HisGlu: 1.399 ± 0.016	0.958HisPhe: 0.958 ± 0.014	1.729HisGly: 1.729 ± 0.021	1.366HisHis: 1.366 ± 0.03	1.398HisIle: 1.398 ± 0.016	1.095HisLys: 1.095 ± 0.016	2.487HisLeu: 2.487 ± 0.025	0.544HisMet: 0.544 ± 0.011	1.107HisAsn: 1.107 ± 0.014	1.68HisPro: 1.68 ± 0.027	1.641HisGln: 1.641 ± 0.024	1.55HisArg: 1.55 ± 0.019	2.383HisSer: 2.383 ± 0.026	1.373HisThr: 1.373 ± 0.016	1.427HisVal: 1.427 ± 0.017	0.295HisTrp: 0.295 ± 0.007	0.875HisTyr: 0.875 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.049IleAla: 4.049 ± 0.03	0.821IleCys: 0.821 ± 0.012	2.945IleAsp: 2.945 ± 0.025	3.362IleGlu: 3.362 ± 0.028	2.043IlePhe: 2.043 ± 0.024	3.222IleGly: 3.222 ± 0.029	1.519IleHis: 1.519 ± 0.018	2.914IleIle: 2.914 ± 0.026	3.089IleLys: 3.089 ± 0.025	5.111IleLeu: 5.111 ± 0.037	1.295IleMet: 1.295 ± 0.017	2.387IleAsn: 2.387 ± 0.023	3.199IlePro: 3.199 ± 0.027	2.553IleGln: 2.553 ± 0.022	2.982IleArg: 2.982 ± 0.026	4.544IleSer: 4.544 ± 0.033	3.149IleThr: 3.149 ± 0.025	3.464IleVal: 3.464 ± 0.032	0.636IleTrp: 0.636 ± 0.012	1.562IleTyr: 1.562 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.542LysAla: 4.542 ± 0.043	0.574LysCys: 0.574 ± 0.011	3.442LysAsp: 3.442 ± 0.029	4.136LysGlu: 4.136 ± 0.039	1.567LysPhe: 1.567 ± 0.017	2.916LysGly: 2.916 ± 0.027	1.323LysHis: 1.323 ± 0.017	2.839LysIle: 2.839 ± 0.025	4.168LysLys: 4.168 ± 0.046	4.356LysLeu: 4.356 ± 0.031	1.302LysMet: 1.302 ± 0.014	2.431LysAsn: 2.431 ± 0.023	2.529LysPro: 2.529 ± 0.026	2.357LysGln: 2.357 ± 0.02	3.511LysArg: 3.511 ± 0.026	4.064LysSer: 4.064 ± 0.033	3.306LysThr: 3.306 ± 0.028	3.249LysVal: 3.249 ± 0.026	0.549LysTrp: 0.549 ± 0.011	1.604LysTyr: 1.604 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	6.652LeuAla: 6.652 ± 0.041	1.236LeuCys: 1.236 ± 0.018	5.174LeuAsp: 5.174 ± 0.035	5.912LeuGlu: 5.912 ± 0.043	3.377LeuPhe: 3.377 ± 0.032	5.046LeuGly: 5.046 ± 0.038	2.257LeuHis: 2.257 ± 0.022	4.491LeuIle: 4.491 ± 0.035	5.252LeuLys: 5.252 ± 0.037	8.19LeuLeu: 8.19 ± 0.052	2.079LeuMet: 2.079 ± 0.022	3.724LeuAsn: 3.724 ± 0.031	4.826LeuPro: 4.826 ± 0.033	4.405LeuGln: 4.405 ± 0.036	4.966LeuArg: 4.966 ± 0.037	8.165LeuSer: 8.165 ± 0.054	5.31LeuThr: 5.31 ± 0.036	5.123LeuVal: 5.123 ± 0.034	0.997LeuTrp: 0.997 ± 0.015	2.478LeuTyr: 2.478 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.108MetAla: 2.108 ± 0.024	0.247MetCys: 0.247 ± 0.007	1.622MetAsp: 1.622 ± 0.019	1.555MetGlu: 1.555 ± 0.015	0.858MetPhe: 0.858 ± 0.013	1.353MetGly: 1.353 ± 0.019	0.52MetHis: 0.52 ± 0.011	1.326MetIle: 1.326 ± 0.017	1.232MetLys: 1.232 ± 0.017	2.067MetLeu: 2.067 ± 0.021	0.729MetMet: 0.729 ± 0.012	1.148MetAsn: 1.148 ± 0.016	1.22MetPro: 1.22 ± 0.015	0.94MetGln: 0.94 ± 0.014	1.207MetArg: 1.207 ± 0.014	2.173MetSer: 2.173 ± 0.021	1.683MetThr: 1.683 ± 0.019	1.489MetVal: 1.489 ± 0.02	0.196MetTrp: 0.196 ± 0.006	0.62MetTyr: 0.62 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.058AsnAla: 3.058 ± 0.029	0.518AsnCys: 0.518 ± 0.01	2.412AsnAsp: 2.412 ± 0.024	2.488AsnGlu: 2.488 ± 0.022	1.359AsnPhe: 1.359 ± 0.017	3.061AsnGly: 3.061 ± 0.032	1.187AsnHis: 1.187 ± 0.016	2.575AsnIle: 2.575 ± 0.021	2.326AsnLys: 2.326 ± 0.022	3.545AsnLeu: 3.545 ± 0.03	1.106AsnMet: 1.106 ± 0.017	3.155AsnAsn: 3.155 ± 0.043	2.381AsnPro: 2.381 ± 0.022	1.838AsnGln: 1.838 ± 0.018	2.172AsnArg: 2.172 ± 0.021	4.095AsnSer: 4.095 ± 0.037	2.812AsnThr: 2.812 ± 0.027	2.544AsnVal: 2.544 ± 0.023	0.47AsnTrp: 0.47 ± 0.008	1.203AsnTyr: 1.203 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	3.712ProAla: 3.712 ± 0.034	0.525ProCys: 0.525 ± 0.011	2.312ProAsp: 2.312 ± 0.023	3.12ProGlu: 3.12 ± 0.025	1.915ProPhe: 1.915 ± 0.02	2.855ProGly: 2.855 ± 0.03	1.337ProHis: 1.337 ± 0.019	2.881ProIle: 2.881 ± 0.026	2.665ProLys: 2.665 ± 0.023	4.65ProLeu: 4.65 ± 0.034	1.172ProMet: 1.172 ± 0.017	2.17ProAsn: 2.17 ± 0.023	3.917ProPro: 3.917 ± 0.054	2.398ProGln: 2.398 ± 0.033	2.579ProArg: 2.579 ± 0.023	6.181ProSer: 6.181 ± 0.051	3.858ProThr: 3.858 ± 0.035	3.146ProVal: 3.146 ± 0.025	0.532ProTrp: 0.532 ± 0.012	1.483ProTyr: 1.483 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.228GlnAla: 3.228 ± 0.032	0.472GlnCys: 0.472 ± 0.012	2.433GlnAsp: 2.433 ± 0.021	3.2GlnGlu: 3.2 ± 0.03	1.437GlnPhe: 1.437 ± 0.019	2.583GlnGly: 2.583 ± 0.024	1.653GlnHis: 1.653 ± 0.029	2.128GlnIle: 2.128 ± 0.023	2.404GlnLys: 2.404 ± 0.021	4.024GlnLeu: 4.024 ± 0.034	1.029GlnMet: 1.029 ± 0.014	1.83GlnAsn: 1.83 ± 0.023	2.47GlnPro: 2.47 ± 0.031	5.904GlnGln: 5.904 ± 0.149	2.774GlnArg: 2.774 ± 0.029	3.67GlnSer: 3.67 ± 0.033	2.413GlnThr: 2.413 ± 0.023	2.226GlnVal: 2.226 ± 0.02	0.488GlnTrp: 0.488 ± 0.01	1.441GlnTyr: 1.441 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	3.712ArgAla: 3.712 ± 0.028	0.677ArgCys: 0.677 ± 0.013	2.817ArgAsp: 2.817 ± 0.035	3.177ArgGlu: 3.177 ± 0.029	1.99ArgPhe: 1.99 ± 0.022	2.94ArgGly: 2.94 ± 0.031	1.624ArgHis: 1.624 ± 0.02	3.041ArgIle: 3.041 ± 0.025	3.301ArgLys: 3.301 ± 0.03	5.016ArgLeu: 5.016 ± 0.038	1.325ArgMet: 1.325 ± 0.017	2.296ArgAsn: 2.296 ± 0.021	2.823ArgPro: 2.823 ± 0.028	2.714ArgGln: 2.714 ± 0.028	4.059ArgArg: 4.059 ± 0.037	4.78ArgSer: 4.78 ± 0.047	3.002ArgThr: 3.002 ± 0.025	2.892ArgVal: 2.892 ± 0.024	0.646ArgTrp: 0.646 ± 0.013	1.606ArgTyr: 1.606 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.203SerAla: 6.203 ± 0.042	0.967SerCys: 0.967 ± 0.016	4.227SerAsp: 4.227 ± 0.032	4.375SerGlu: 4.375 ± 0.037	3.302SerPhe: 3.302 ± 0.028	5.362SerGly: 5.362 ± 0.044	2.254SerHis: 2.254 ± 0.026	5.082SerIle: 5.082 ± 0.029	4.628SerLys: 4.628 ± 0.037	7.95SerLeu: 7.95 ± 0.046	2.103SerMet: 2.103 ± 0.023	4.507SerAsn: 4.507 ± 0.041	5.558SerPro: 5.558 ± 0.058	3.707SerGln: 3.707 ± 0.034	4.746SerArg: 4.746 ± 0.046	12.659SerSer: 12.659 ± 0.108	6.856SerThr: 6.856 ± 0.046	4.719SerVal: 4.719 ± 0.029	0.887SerTrp: 0.887 ± 0.013	2.205SerTyr: 2.205 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	4.928ThrAla: 4.928 ± 0.034	0.714ThrCys: 0.714 ± 0.011	2.671ThrAsp: 2.671 ± 0.024	3.156ThrGlu: 3.156 ± 0.029	2.285ThrPhe: 2.285 ± 0.022	3.72ThrGly: 3.72 ± 0.028	1.389ThrHis: 1.389 ± 0.016	3.749ThrIle: 3.749 ± 0.028	3.094ThrLys: 3.094 ± 0.025	5.679ThrLeu: 5.679 ± 0.041	1.49ThrMet: 1.49 ± 0.019	2.683ThrAsn: 2.683 ± 0.026	3.888ThrPro: 3.888 ± 0.034	2.273ThrGln: 2.273 ± 0.022	2.909ThrArg: 2.909 ± 0.023	6.274ThrSer: 6.274 ± 0.045	5.337ThrThr: 5.337 ± 0.051	3.726ThrVal: 3.726 ± 0.03	0.655ThrTrp: 0.655 ± 0.012	1.458ThrTyr: 1.458 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	4.451ValAla: 4.451 ± 0.033	0.829ValCys: 0.829 ± 0.013	3.432ValAsp: 3.432 ± 0.028	3.54ValGlu: 3.54 ± 0.032	2.358ValPhe: 2.358 ± 0.023	3.409ValGly: 3.409 ± 0.032	1.407ValHis: 1.407 ± 0.018	3.246ValIle: 3.246 ± 0.029	3.122ValLys: 3.122 ± 0.027	5.346ValLeu: 5.346 ± 0.036	1.429ValMet: 1.429 ± 0.016	2.389ValAsn: 2.389 ± 0.025	3.157ValPro: 3.157 ± 0.027	2.423ValGln: 2.423 ± 0.022	2.869ValArg: 2.869 ± 0.025	4.629ValSer: 4.629 ± 0.031	3.307ValThr: 3.307 ± 0.027	3.915ValVal: 3.915 ± 0.033	0.633ValTrp: 0.633 ± 0.013	1.683ValTyr: 1.683 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	0.706TrpAla: 0.706 ± 0.012	0.175TrpCys: 0.175 ± 0.006	0.698TrpAsp: 0.698 ± 0.013	0.613TrpGlu: 0.613 ± 0.01	0.445TrpPhe: 0.445 ± 0.012	0.603TrpGly: 0.603 ± 0.012	0.268TrpHis: 0.268 ± 0.008	0.712TrpIle: 0.712 ± 0.011	0.685TrpLys: 0.685 ± 0.012	0.964TrpLeu: 0.964 ± 0.016	0.329TrpMet: 0.329 ± 0.007	0.516TrpAsn: 0.516 ± 0.011	0.422TrpPro: 0.422 ± 0.01	0.397TrpGln: 0.397 ± 0.01	0.698TrpArg: 0.698 ± 0.013	0.905TrpSer: 0.905 ± 0.015	0.737TrpThr: 0.737 ± 0.013	0.655TrpVal: 0.655 ± 0.01	0.178TrpTrp: 0.178 ± 0.008	0.33TrpTyr: 0.33 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.756TyrAla: 1.756 ± 0.018	0.493TyrCys: 0.493 ± 0.01	1.678TyrAsp: 1.678 ± 0.019	1.606TyrGlu: 1.606 ± 0.018	1.243TyrPhe: 1.243 ± 0.017	1.882TyrGly: 1.882 ± 0.022	0.893TyrHis: 0.893 ± 0.013	1.543TyrIle: 1.543 ± 0.019	1.461TyrLys: 1.461 ± 0.019	2.686TyrLeu: 2.686 ± 0.023	0.708TyrMet: 0.708 ± 0.013	1.358TyrAsn: 1.358 ± 0.019	1.47TyrPro: 1.47 ± 0.02	1.381TyrGln: 1.381 ± 0.019	1.65TyrArg: 1.65 ± 0.02	2.328TyrSer: 2.328 ± 0.021	1.531TyrThr: 1.531 ± 0.019	1.56TyrVal: 1.56 ± 0.019	0.352TyrTrp: 0.352 ± 0.01	1.049TyrTyr: 1.049 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11597 proteins (5469817 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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