Amino acid dipepetide frequency for Lake Sarah-associated circular virus-33

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.096AlaAla: 3.096 ± 2.75
0.0AlaCys: 0.0 ± 0.0
4.644AlaAsp: 4.644 ± 2.878
1.548AlaGlu: 1.548 ± 0.959
3.096AlaPhe: 3.096 ± 2.75
7.74AlaGly: 7.74 ± 2.206
0.0AlaHis: 0.0 ± 0.0
4.644AlaIle: 4.644 ± 0.544
4.644AlaLys: 4.644 ± 2.878
6.192AlaLeu: 6.192 ± 1.503
4.644AlaMet: 4.644 ± 2.878
3.096AlaAsn: 3.096 ± 2.75
3.096AlaPro: 3.096 ± 1.919
1.548AlaGln: 1.548 ± 1.375
0.0AlaArg: 0.0 ± 0.0
3.096AlaSer: 3.096 ± 0.416
3.096AlaThr: 3.096 ± 0.416
6.192AlaVal: 6.192 ± 0.831
3.096AlaTrp: 3.096 ± 1.919
4.644AlaTyr: 4.644 ± 0.544
0.0AlaXaa: 0.0 ± 0.0
Cys
3.096CysAla: 3.096 ± 1.919
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.548CysGly: 1.548 ± 0.959
1.548CysHis: 1.548 ± 1.375
1.548CysIle: 1.548 ± 0.959
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.548CysPro: 1.548 ± 0.959
0.0CysGln: 0.0 ± 0.0
1.548CysArg: 1.548 ± 0.959
0.0CysSer: 0.0 ± 0.0
1.548CysThr: 1.548 ± 0.959
1.548CysVal: 1.548 ± 0.959
1.548CysTrp: 1.548 ± 1.375
1.548CysTyr: 1.548 ± 0.959
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
1.548AspCys: 1.548 ± 1.375
7.74AspAsp: 7.74 ± 2.463
1.548AspGlu: 1.548 ± 0.959
0.0AspPhe: 0.0 ± 0.0
0.0AspGly: 0.0 ± 0.0
4.644AspHis: 4.644 ± 0.544
3.096AspIle: 3.096 ± 0.416
4.644AspLys: 4.644 ± 0.544
6.192AspLeu: 6.192 ± 1.503
0.0AspMet: 0.0 ± 0.0
1.548AspAsn: 1.548 ± 0.959
7.74AspPro: 7.74 ± 2.463
1.548AspGln: 1.548 ± 1.375
1.548AspArg: 1.548 ± 0.959
0.0AspSer: 0.0 ± 0.0
1.548AspThr: 1.548 ± 0.959
3.096AspVal: 3.096 ± 0.416
1.548AspTrp: 1.548 ± 1.375
3.096AspTyr: 3.096 ± 1.919
0.0AspXaa: 0.0 ± 0.0
Glu
7.74GluAla: 7.74 ± 4.797
0.0GluCys: 0.0 ± 0.0
1.548GluAsp: 1.548 ± 0.959
4.644GluGlu: 4.644 ± 2.878
1.548GluPhe: 1.548 ± 0.959
3.096GluGly: 3.096 ± 1.919
1.548GluHis: 1.548 ± 0.959
1.548GluIle: 1.548 ± 1.375
7.74GluLys: 7.74 ± 2.463
0.0GluLeu: 0.0 ± 0.0
3.096GluMet: 3.096 ± 1.919
1.548GluAsn: 1.548 ± 0.959
0.0GluPro: 0.0 ± 0.0
1.548GluGln: 1.548 ± 0.959
3.096GluArg: 3.096 ± 1.919
1.548GluSer: 1.548 ± 0.959
3.096GluThr: 3.096 ± 1.919
1.548GluVal: 1.548 ± 0.959
1.548GluTrp: 1.548 ± 0.959
4.644GluTyr: 4.644 ± 2.878
0.0GluXaa: 0.0 ± 0.0
Phe
1.548PheAla: 1.548 ± 1.375
0.0PheCys: 0.0 ± 0.0
3.096PheAsp: 3.096 ± 0.416
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
3.096PheGly: 3.096 ± 0.416
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
4.644PheLys: 4.644 ± 0.544
3.096PheLeu: 3.096 ± 2.75
0.0PheMet: 0.0 ± 0.0
1.548PheAsn: 1.548 ± 1.375
1.548PhePro: 1.548 ± 1.375
1.548PheGln: 1.548 ± 0.959
3.096PheArg: 3.096 ± 2.75
0.0PheSer: 0.0 ± 0.0
10.836PheThr: 10.836 ± 4.956
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
3.096PheTyr: 3.096 ± 0.416
0.0PheXaa: 0.0 ± 0.0
Gly
3.096GlyAla: 3.096 ± 0.416
0.0GlyCys: 0.0 ± 0.0
3.096GlyAsp: 3.096 ± 1.919
3.096GlyGlu: 3.096 ± 0.416
3.096GlyPhe: 3.096 ± 2.75
6.192GlyGly: 6.192 ± 3.166
1.548GlyHis: 1.548 ± 0.959
1.548GlyIle: 1.548 ± 1.375
7.74GlyLys: 7.74 ± 0.128
9.288GlyLeu: 9.288 ± 3.581
1.548GlyMet: 1.548 ± 0.959
1.548GlyAsn: 1.548 ± 0.959
3.096GlyPro: 3.096 ± 0.416
7.74GlyGln: 7.74 ± 0.128
4.644GlyArg: 4.644 ± 4.125
3.096GlySer: 3.096 ± 2.75
4.644GlyThr: 4.644 ± 1.791
1.548GlyVal: 1.548 ± 1.375
0.0GlyTrp: 0.0 ± 0.0
3.096GlyTyr: 3.096 ± 0.416
0.0GlyXaa: 0.0 ± 0.0
His
1.548HisAla: 1.548 ± 1.375
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
3.096HisGlu: 3.096 ± 1.919
0.0HisPhe: 0.0 ± 0.0
3.096HisGly: 3.096 ± 0.416
0.0HisHis: 0.0 ± 0.0
3.096HisIle: 3.096 ± 1.919
0.0HisLys: 0.0 ± 0.0
1.548HisLeu: 1.548 ± 0.959
0.0HisMet: 0.0 ± 0.0
1.548HisAsn: 1.548 ± 1.375
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.548HisSer: 1.548 ± 1.375
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.548HisTyr: 1.548 ± 0.959
0.0HisXaa: 0.0 ± 0.0
Ile
7.74IleAla: 7.74 ± 0.128
0.0IleCys: 0.0 ± 0.0
6.192IleAsp: 6.192 ± 3.838
4.644IleGlu: 4.644 ± 2.878
1.548IlePhe: 1.548 ± 1.375
3.096IleGly: 3.096 ± 2.75
1.548IleHis: 1.548 ± 0.959
6.192IleIle: 6.192 ± 1.503
4.644IleLys: 4.644 ± 1.791
1.548IleLeu: 1.548 ± 0.959
0.0IleMet: 0.0 ± 0.709
4.644IleAsn: 4.644 ± 1.791
3.096IlePro: 3.096 ± 0.416
3.096IleGln: 3.096 ± 1.919
4.644IleArg: 4.644 ± 1.791
1.548IleSer: 1.548 ± 0.959
1.548IleThr: 1.548 ± 1.375
3.096IleVal: 3.096 ± 1.919
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.644LysAla: 4.644 ± 2.878
6.192LysCys: 6.192 ± 3.838
1.548LysAsp: 1.548 ± 1.375
3.096LysGlu: 3.096 ± 1.919
3.096LysPhe: 3.096 ± 2.75
3.096LysGly: 3.096 ± 1.919
1.548LysHis: 1.548 ± 0.959
3.096LysIle: 3.096 ± 1.919
13.932LysLys: 13.932 ± 5.372
9.288LysLeu: 9.288 ± 1.088
1.548LysMet: 1.548 ± 1.375
1.548LysAsn: 1.548 ± 1.375
1.548LysPro: 1.548 ± 1.375
0.0LysGln: 0.0 ± 0.0
10.836LysArg: 10.836 ± 2.047
9.288LysSer: 9.288 ± 1.088
12.384LysThr: 12.384 ± 1.662
3.096LysVal: 3.096 ± 0.416
4.644LysTrp: 4.644 ± 2.878
1.548LysTyr: 1.548 ± 1.375
0.0LysXaa: 0.0 ± 0.0
Leu
7.74LeuAla: 7.74 ± 0.128
0.0LeuCys: 0.0 ± 0.0
1.548LeuAsp: 1.548 ± 0.959
6.192LeuGlu: 6.192 ± 3.838
4.644LeuPhe: 4.644 ± 1.791
4.644LeuGly: 4.644 ± 1.791
0.0LeuHis: 0.0 ± 0.0
4.644LeuIle: 4.644 ± 0.544
10.836LeuLys: 10.836 ± 4.382
9.288LeuLeu: 9.288 ± 5.916
0.0LeuMet: 0.0 ± 0.0
4.644LeuAsn: 4.644 ± 0.544
4.644LeuPro: 4.644 ± 0.544
3.096LeuGln: 3.096 ± 0.416
1.548LeuArg: 1.548 ± 0.959
4.644LeuSer: 4.644 ± 0.544
7.74LeuThr: 7.74 ± 2.206
1.548LeuVal: 1.548 ± 1.375
1.548LeuTrp: 1.548 ± 0.959
3.096LeuTyr: 3.096 ± 2.75
0.0LeuXaa: 0.0 ± 0.0
Met
1.548MetAla: 1.548 ± 0.959
3.096MetCys: 3.096 ± 1.919
1.548MetAsp: 1.548 ± 0.959
1.548MetGlu: 1.548 ± 0.959
0.0MetPhe: 0.0 ± 0.0
1.548MetGly: 1.548 ± 0.959
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.548MetLeu: 1.548 ± 0.959
1.548MetMet: 1.548 ± 0.959
4.644MetAsn: 4.644 ± 0.544
1.548MetPro: 1.548 ± 0.959
0.0MetGln: 0.0 ± 0.0
4.644MetArg: 4.644 ± 1.791
0.0MetSer: 0.0 ± 0.0
3.096MetThr: 3.096 ± 1.919
1.548MetVal: 1.548 ± 1.375
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.096AsnAla: 3.096 ± 0.416
0.0AsnCys: 0.0 ± 0.0
1.548AsnAsp: 1.548 ± 1.375
3.096AsnGlu: 3.096 ± 1.919
0.0AsnPhe: 0.0 ± 0.0
1.548AsnGly: 1.548 ± 1.375
1.548AsnHis: 1.548 ± 1.375
0.0AsnIle: 0.0 ± 0.0
7.74AsnLys: 7.74 ± 0.128
4.644AsnLeu: 4.644 ± 1.791
1.548AsnMet: 1.548 ± 0.959
6.192AsnAsn: 6.192 ± 0.831
3.096AsnPro: 3.096 ± 1.919
1.548AsnGln: 1.548 ± 1.375
0.0AsnArg: 0.0 ± 0.0
0.0AsnSer: 0.0 ± 0.0
1.548AsnThr: 1.548 ± 1.375
1.548AsnVal: 1.548 ± 1.375
0.0AsnTrp: 0.0 ± 0.0
4.644AsnTyr: 4.644 ± 4.125
0.0AsnXaa: 0.0 ± 0.0
Pro
7.74ProAla: 7.74 ± 2.206
1.548ProCys: 1.548 ± 1.375
1.548ProAsp: 1.548 ± 0.959
3.096ProGlu: 3.096 ± 1.919
0.0ProPhe: 0.0 ± 0.0
3.096ProGly: 3.096 ± 2.75
0.0ProHis: 0.0 ± 0.0
7.74ProIle: 7.74 ± 2.463
3.096ProLys: 3.096 ± 1.919
3.096ProLeu: 3.096 ± 1.919
4.644ProMet: 4.644 ± 0.544
1.548ProAsn: 1.548 ± 1.375
4.644ProPro: 4.644 ± 0.544
0.0ProGln: 0.0 ± 0.0
3.096ProArg: 3.096 ± 1.919
0.0ProSer: 0.0 ± 0.0
4.644ProThr: 4.644 ± 1.791
3.096ProVal: 3.096 ± 1.919
1.548ProTrp: 1.548 ± 0.959
1.548ProTyr: 1.548 ± 0.959
0.0ProXaa: 0.0 ± 0.0
Gln
1.548GlnAla: 1.548 ± 1.375
0.0GlnCys: 0.0 ± 0.0
3.096GlnAsp: 3.096 ± 2.75
1.548GlnGlu: 1.548 ± 0.959
1.548GlnPhe: 1.548 ± 1.375
6.192GlnGly: 6.192 ± 1.503
0.0GlnHis: 0.0 ± 0.0
1.548GlnIle: 1.548 ± 1.375
0.0GlnLys: 0.0 ± 0.0
7.74GlnLeu: 7.74 ± 2.463
0.0GlnMet: 0.0 ± 0.0
1.548GlnAsn: 1.548 ± 1.375
0.0GlnPro: 0.0 ± 0.0
3.096GlnGln: 3.096 ± 0.416
1.548GlnArg: 1.548 ± 0.959
4.644GlnSer: 4.644 ± 0.544
3.096GlnThr: 3.096 ± 1.919
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.548GlnTyr: 1.548 ± 0.959
0.0GlnXaa: 0.0 ± 0.0
Arg
1.548ArgAla: 1.548 ± 0.959
0.0ArgCys: 0.0 ± 0.0
1.548ArgAsp: 1.548 ± 0.959
3.096ArgGlu: 3.096 ± 1.919
3.096ArgPhe: 3.096 ± 0.416
4.644ArgGly: 4.644 ± 1.791
1.548ArgHis: 1.548 ± 0.959
3.096ArgIle: 3.096 ± 0.416
7.74ArgLys: 7.74 ± 4.541
0.0ArgLeu: 0.0 ± 0.0
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
4.644ArgPro: 4.644 ± 2.878
1.548ArgGln: 1.548 ± 1.375
4.644ArgArg: 4.644 ± 1.791
3.096ArgSer: 3.096 ± 0.416
3.096ArgThr: 3.096 ± 2.75
1.548ArgVal: 1.548 ± 0.959
3.096ArgTrp: 3.096 ± 1.919
3.096ArgTyr: 3.096 ± 2.75
0.0ArgXaa: 0.0 ± 0.0
Ser
4.644SerAla: 4.644 ± 0.544
0.0SerCys: 0.0 ± 0.0
1.548SerAsp: 1.548 ± 0.959
0.0SerGlu: 0.0 ± 0.0
1.548SerPhe: 1.548 ± 1.375
3.096SerGly: 3.096 ± 0.416
0.0SerHis: 0.0 ± 0.0
4.644SerIle: 4.644 ± 0.544
4.644SerLys: 4.644 ± 0.544
4.644SerLeu: 4.644 ± 0.544
0.0SerMet: 0.0 ± 0.0
1.548SerAsn: 1.548 ± 1.375
3.096SerPro: 3.096 ± 2.75
4.644SerGln: 4.644 ± 2.878
1.548SerArg: 1.548 ± 1.375
1.548SerSer: 1.548 ± 1.375
6.192SerThr: 6.192 ± 3.166
0.0SerVal: 0.0 ± 0.0
3.096SerTrp: 3.096 ± 0.416
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.096ThrAla: 3.096 ± 0.416
1.548ThrCys: 1.548 ± 0.959
4.644ThrAsp: 4.644 ± 4.125
1.548ThrGlu: 1.548 ± 0.959
6.192ThrPhe: 6.192 ± 1.503
6.192ThrGly: 6.192 ± 5.5
1.548ThrHis: 1.548 ± 1.375
6.192ThrIle: 6.192 ± 0.831
6.192ThrLys: 6.192 ± 0.831
6.192ThrLeu: 6.192 ± 3.166
1.548ThrMet: 1.548 ± 0.959
1.548ThrAsn: 1.548 ± 1.375
7.74ThrPro: 7.74 ± 0.128
4.644ThrGln: 4.644 ± 0.544
0.0ThrArg: 0.0 ± 0.0
6.192ThrSer: 6.192 ± 0.831
9.288ThrThr: 9.288 ± 3.422
1.548ThrVal: 1.548 ± 1.375
1.548ThrTrp: 1.548 ± 0.959
3.096ThrTyr: 3.096 ± 0.416
0.0ThrXaa: 0.0 ± 0.0
Val
1.548ValAla: 1.548 ± 1.375
1.548ValCys: 1.548 ± 0.959
4.644ValAsp: 4.644 ± 0.544
1.548ValGlu: 1.548 ± 0.959
4.644ValPhe: 4.644 ± 1.791
3.096ValGly: 3.096 ± 0.416
0.0ValHis: 0.0 ± 0.0
3.096ValIle: 3.096 ± 0.416
1.548ValLys: 1.548 ± 0.959
1.548ValLeu: 1.548 ± 0.959
3.096ValMet: 3.096 ± 2.119
0.0ValAsn: 0.0 ± 0.0
1.548ValPro: 1.548 ± 0.959
1.548ValGln: 1.548 ± 1.375
1.548ValArg: 1.548 ± 1.375
0.0ValSer: 0.0 ± 0.0
1.548ValThr: 1.548 ± 0.959
3.096ValVal: 3.096 ± 1.919
1.548ValTrp: 1.548 ± 0.959
1.548ValTyr: 1.548 ± 1.375
0.0ValXaa: 0.0 ± 0.0
Trp
3.096TrpAla: 3.096 ± 1.919
0.0TrpCys: 0.0 ± 0.0
1.548TrpAsp: 1.548 ± 0.959
1.548TrpGlu: 1.548 ± 0.959
1.548TrpPhe: 1.548 ± 0.959
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.548TrpIle: 1.548 ± 0.959
3.096TrpLys: 3.096 ± 0.416
3.096TrpLeu: 3.096 ± 1.919
1.548TrpMet: 1.548 ± 0.959
0.0TrpAsn: 0.0 ± 0.0
3.096TrpPro: 3.096 ± 0.416
0.0TrpGln: 0.0 ± 0.0
1.548TrpArg: 1.548 ± 0.959
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
3.096TrpVal: 3.096 ± 0.416
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.548TyrCys: 1.548 ± 0.959
0.0TyrAsp: 0.0 ± 0.0
6.192TyrGlu: 6.192 ± 1.503
1.548TyrPhe: 1.548 ± 1.375
4.644TyrGly: 4.644 ± 1.791
0.0TyrHis: 0.0 ± 0.0
3.096TyrIle: 3.096 ± 0.416
3.096TyrLys: 3.096 ± 1.919
3.096TyrLeu: 3.096 ± 0.416
1.548TyrMet: 1.548 ± 0.959
4.644TyrAsn: 4.644 ± 0.544
0.0TyrPro: 0.0 ± 0.0
1.548TyrGln: 1.548 ± 0.959
1.548TyrArg: 1.548 ± 1.375
6.192TyrSer: 6.192 ± 3.166
1.548TyrThr: 1.548 ± 1.375
1.548TyrVal: 1.548 ± 1.375
0.0TyrTrp: 0.0 ± 0.0
3.096TyrTyr: 3.096 ± 2.75
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (647 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski