Amino acid dipepetide frequency for Devosia chinhatensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.748AlaAla: 15.748 ± 0.181	0.779AlaCys: 0.779 ± 0.034	7.058AlaAsp: 7.058 ± 0.093	7.828AlaGlu: 7.828 ± 0.114	4.427AlaPhe: 4.427 ± 0.079	10.627AlaGly: 10.627 ± 0.116	2.157AlaHis: 2.157 ± 0.056	6.99AlaIle: 6.99 ± 0.082	3.459AlaLys: 3.459 ± 0.071	14.236AlaLeu: 14.236 ± 0.169	3.822AlaMet: 3.822 ± 0.071	3.26AlaAsn: 3.26 ± 0.061	5.214AlaPro: 5.214 ± 0.095	4.326AlaGln: 4.326 ± 0.071	8.227AlaArg: 8.227 ± 0.121	6.395AlaSer: 6.395 ± 0.082	5.702AlaThr: 5.702 ± 0.083	8.409AlaVal: 8.409 ± 0.11	1.362AlaTrp: 1.362 ± 0.041	2.619AlaTyr: 2.619 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.779CysAla: 0.779 ± 0.031	0.081CysCys: 0.081 ± 0.01	0.433CysAsp: 0.433 ± 0.024	0.329CysGlu: 0.329 ± 0.017	0.27CysPhe: 0.27 ± 0.017	0.729CysGly: 0.729 ± 0.028	0.193CysHis: 0.193 ± 0.016	0.315CysIle: 0.315 ± 0.017	0.15CysLys: 0.15 ± 0.013	0.695CysLeu: 0.695 ± 0.026	0.116CysMet: 0.116 ± 0.009	0.169CysAsn: 0.169 ± 0.014	0.339CysPro: 0.339 ± 0.018	0.18CysGln: 0.18 ± 0.016	0.431CysArg: 0.431 ± 0.024	0.339CysSer: 0.339 ± 0.019	0.332CysThr: 0.332 ± 0.019	0.437CysVal: 0.437 ± 0.021	0.087CysTrp: 0.087 ± 0.009	0.158CysTyr: 0.158 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.183AspAla: 7.183 ± 0.097	0.378AspCys: 0.378 ± 0.023	3.122AspAsp: 3.122 ± 0.071	3.54AspGlu: 3.54 ± 0.071	2.4AspPhe: 2.4 ± 0.055	5.133AspGly: 5.133 ± 0.09	1.281AspHis: 1.281 ± 0.04	3.635AspIle: 3.635 ± 0.064	1.782AspLys: 1.782 ± 0.046	6.149AspLeu: 6.149 ± 0.081	1.483AspMet: 1.483 ± 0.036	1.603AspAsn: 1.603 ± 0.044	3.447AspPro: 3.447 ± 0.061	1.869AspGln: 1.869 ± 0.042	4.092AspArg: 4.092 ± 0.073	2.214AspSer: 2.214 ± 0.049	2.643AspThr: 2.643 ± 0.062	4.295AspVal: 4.295 ± 0.071	1.013AspTrp: 1.013 ± 0.037	1.587AspTyr: 1.587 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	7.678GluAla: 7.678 ± 0.112	0.293GluCys: 0.293 ± 0.022	3.094GluAsp: 3.094 ± 0.065	3.193GluGlu: 3.193 ± 0.075	1.724GluPhe: 1.724 ± 0.047	4.474GluGly: 4.474 ± 0.083	1.17GluHis: 1.17 ± 0.038	3.481GluIle: 3.481 ± 0.067	2.239GluLys: 2.239 ± 0.058	5.212GluLeu: 5.212 ± 0.084	1.581GluMet: 1.581 ± 0.039	1.622GluAsn: 1.622 ± 0.044	2.749GluPro: 2.749 ± 0.061	2.276GluGln: 2.276 ± 0.053	4.555GluArg: 4.555 ± 0.074	2.254GluSer: 2.254 ± 0.051	3.582GluThr: 3.582 ± 0.063	3.809GluVal: 3.809 ± 0.07	0.665GluTrp: 0.665 ± 0.027	0.958GluTyr: 0.958 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	4.832PheAla: 4.832 ± 0.065	0.335PheCys: 0.335 ± 0.02	2.729PheAsp: 2.729 ± 0.05	2.256PheGlu: 2.256 ± 0.053	1.607PhePhe: 1.607 ± 0.058	3.92PheGly: 3.92 ± 0.081	0.715PheHis: 0.715 ± 0.027	1.884PheIle: 1.884 ± 0.045	0.994PheLys: 0.994 ± 0.032	3.423PheLeu: 3.423 ± 0.074	0.859PheMet: 0.859 ± 0.028	1.151PheAsn: 1.151 ± 0.039	1.619PhePro: 1.619 ± 0.045	1.051PheGln: 1.051 ± 0.035	2.061PheArg: 2.061 ± 0.05	2.405PheSer: 2.405 ± 0.055	2.105PheThr: 2.105 ± 0.047	3.004PheVal: 3.004 ± 0.063	0.609PheTrp: 0.609 ± 0.025	1.013PheTyr: 1.013 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	9.204GlyAla: 9.204 ± 0.1	0.633GlyCys: 0.633 ± 0.024	4.54GlyAsp: 4.54 ± 0.091	4.876GlyGlu: 4.876 ± 0.078	3.677GlyPhe: 3.677 ± 0.063	7.272GlyGly: 7.272 ± 0.161	1.894GlyHis: 1.894 ± 0.045	4.945GlyIle: 4.945 ± 0.076	3.349GlyLys: 3.349 ± 0.073	9.438GlyLeu: 9.438 ± 0.124	2.373GlyMet: 2.373 ± 0.049	2.603GlyAsn: 2.603 ± 0.077	3.409GlyPro: 3.409 ± 0.063	3.323GlyGln: 3.323 ± 0.059	5.773GlyArg: 5.773 ± 0.083	4.478GlySer: 4.478 ± 0.074	4.843GlyThr: 4.843 ± 0.116	6.042GlyVal: 6.042 ± 0.087	1.332GlyTrp: 1.332 ± 0.036	2.264GlyTyr: 2.264 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.269HisAla: 2.269 ± 0.057	0.182HisCys: 0.182 ± 0.014	1.287HisAsp: 1.287 ± 0.046	1.024HisGlu: 1.024 ± 0.037	0.93HisPhe: 0.93 ± 0.033	1.824HisGly: 1.824 ± 0.043	0.59HisHis: 0.59 ± 0.027	1.025HisIle: 1.025 ± 0.035	0.526HisLys: 0.526 ± 0.023	2.017HisLeu: 2.017 ± 0.049	0.533HisMet: 0.533 ± 0.024	0.536HisAsn: 0.536 ± 0.023	1.19HisPro: 1.19 ± 0.036	0.627HisGln: 0.627 ± 0.025	1.361HisArg: 1.361 ± 0.046	0.907HisSer: 0.907 ± 0.03	0.803HisThr: 0.803 ± 0.031	1.405HisVal: 1.405 ± 0.039	0.338HisTrp: 0.338 ± 0.019	0.568HisTyr: 0.568 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	7.909IleAla: 7.909 ± 0.098	0.446IleCys: 0.446 ± 0.02	3.911IleAsp: 3.911 ± 0.075	3.802IleGlu: 3.802 ± 0.069	1.984IlePhe: 1.984 ± 0.06	5.333IleGly: 5.333 ± 0.074	0.899IleHis: 0.899 ± 0.035	2.851IleIle: 2.851 ± 0.071	1.442IleLys: 1.442 ± 0.039	4.964IleLeu: 4.964 ± 0.091	1.158IleMet: 1.158 ± 0.034	1.596IleAsn: 1.596 ± 0.045	2.382IlePro: 2.382 ± 0.054	1.326IleGln: 1.326 ± 0.036	3.135IleArg: 3.135 ± 0.06	3.113IleSer: 3.113 ± 0.056	2.821IleThr: 2.821 ± 0.056	4.658IleVal: 4.658 ± 0.072	0.629IleTrp: 0.629 ± 0.024	1.24IleTyr: 1.24 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.069LysAla: 4.069 ± 0.084	0.123LysCys: 0.123 ± 0.011	1.672LysAsp: 1.672 ± 0.046	1.344LysGlu: 1.344 ± 0.042	0.852LysPhe: 0.852 ± 0.029	2.558LysGly: 2.558 ± 0.057	0.577LysHis: 0.577 ± 0.027	1.511LysIle: 1.511 ± 0.044	1.168LysLys: 1.168 ± 0.051	2.973LysLeu: 2.973 ± 0.061	0.718LysMet: 0.718 ± 0.027	0.743LysAsn: 0.743 ± 0.026	1.922LysPro: 1.922 ± 0.049	0.955LysGln: 0.955 ± 0.036	2.197LysArg: 2.197 ± 0.052	1.832LysSer: 1.832 ± 0.041	1.774LysThr: 1.774 ± 0.048	2.482LysVal: 2.482 ± 0.056	0.377LysTrp: 0.377 ± 0.021	0.548LysTyr: 0.548 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	13.88LeuAla: 13.88 ± 0.168	0.769LeuCys: 0.769 ± 0.033	6.614LeuAsp: 6.614 ± 0.088	5.423LeuGlu: 5.423 ± 0.087	3.889LeuPhe: 3.889 ± 0.073	8.754LeuGly: 8.754 ± 0.118	1.808LeuHis: 1.808 ± 0.048	5.439LeuIle: 5.439 ± 0.094	3.218LeuLys: 3.218 ± 0.062	9.711LeuLeu: 9.711 ± 0.158	2.497LeuMet: 2.497 ± 0.051	2.827LeuAsn: 2.827 ± 0.056	5.51LeuPro: 5.51 ± 0.083	2.646LeuGln: 2.646 ± 0.053	6.467LeuArg: 6.467 ± 0.105	6.83LeuSer: 6.83 ± 0.091	5.777LeuThr: 5.777 ± 0.089	8.28LeuVal: 8.28 ± 0.117	1.125LeuTrp: 1.125 ± 0.039	2.158LeuTyr: 2.158 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	3.457MetAla: 3.457 ± 0.061	0.114MetCys: 0.114 ± 0.01	1.271MetAsp: 1.271 ± 0.034	1.079MetGlu: 1.079 ± 0.037	0.763MetPhe: 0.763 ± 0.028	2.092MetGly: 2.092 ± 0.047	0.449MetHis: 0.449 ± 0.023	1.351MetIle: 1.351 ± 0.037	0.819MetLys: 0.819 ± 0.033	2.684MetLeu: 2.684 ± 0.06	0.673MetMet: 0.673 ± 0.028	0.763MetAsn: 0.763 ± 0.028	1.553MetPro: 1.553 ± 0.043	0.856MetGln: 0.856 ± 0.031	1.788MetArg: 1.788 ± 0.046	1.799MetSer: 1.799 ± 0.045	1.861MetThr: 1.861 ± 0.042	2.011MetVal: 2.011 ± 0.049	0.197MetTrp: 0.197 ± 0.013	0.306MetTyr: 0.306 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.487AsnAla: 3.487 ± 0.064	0.183AsnCys: 0.183 ± 0.014	1.487AsnAsp: 1.487 ± 0.052	1.311AsnGlu: 1.311 ± 0.043	1.08AsnPhe: 1.08 ± 0.035	2.669AsnGly: 2.669 ± 0.07	0.547AsnHis: 0.547 ± 0.026	1.507AsnIle: 1.507 ± 0.04	0.751AsnLys: 0.751 ± 0.029	2.828AsnLeu: 2.828 ± 0.059	0.654AsnMet: 0.654 ± 0.028	0.803AsnAsn: 0.803 ± 0.035	1.905AsnPro: 1.905 ± 0.05	0.897AsnGln: 0.897 ± 0.031	1.835AsnArg: 1.835 ± 0.042	1.443AsnSer: 1.443 ± 0.05	1.329AsnThr: 1.329 ± 0.038	2.142AsnVal: 2.142 ± 0.047	0.504AsnTrp: 0.504 ± 0.023	0.74AsnTyr: 0.74 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	5.89ProAla: 5.89 ± 0.11	0.226ProCys: 0.226 ± 0.015	3.601ProAsp: 3.601 ± 0.058	3.565ProGlu: 3.565 ± 0.061	2.025ProPhe: 2.025 ± 0.04	4.327ProGly: 4.327 ± 0.071	1.051ProHis: 1.051 ± 0.038	2.525ProIle: 2.525 ± 0.052	1.43ProLys: 1.43 ± 0.043	4.752ProLeu: 4.752 ± 0.073	1.2ProMet: 1.2 ± 0.032	1.454ProAsn: 1.454 ± 0.039	2.138ProPro: 2.138 ± 0.058	1.745ProGln: 1.745 ± 0.038	2.683ProArg: 2.683 ± 0.062	2.644ProSer: 2.644 ± 0.058	2.381ProThr: 2.381 ± 0.053	4.15ProVal: 4.15 ± 0.067	0.652ProTrp: 0.652 ± 0.03	1.179ProTyr: 1.179 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.135GlnAla: 4.135 ± 0.074	0.191GlnCys: 0.191 ± 0.015	1.676GlnAsp: 1.676 ± 0.045	1.444GlnGlu: 1.444 ± 0.046	1.278GlnPhe: 1.278 ± 0.036	2.54GlnGly: 2.54 ± 0.061	0.657GlnHis: 0.657 ± 0.025	1.985GlnIle: 1.985 ± 0.046	1.029GlnLys: 1.029 ± 0.034	3.182GlnLeu: 3.182 ± 0.055	1.024GlnMet: 1.024 ± 0.03	0.939GlnAsn: 0.939 ± 0.035	1.741GlnPro: 1.741 ± 0.04	1.253GlnGln: 1.253 ± 0.042	2.546GlnArg: 2.546 ± 0.062	2.026GlnSer: 2.026 ± 0.049	1.884GlnThr: 1.884 ± 0.042	2.472GlnVal: 2.472 ± 0.056	0.375GlnTrp: 0.375 ± 0.023	0.66GlnTyr: 0.66 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	7.313ArgAla: 7.313 ± 0.113	0.37ArgCys: 0.37 ± 0.021	4.011ArgAsp: 4.011 ± 0.065	3.687ArgGlu: 3.687 ± 0.078	2.831ArgPhe: 2.831 ± 0.052	4.394ArgGly: 4.394 ± 0.079	1.575ArgHis: 1.575 ± 0.043	3.877ArgIle: 3.877 ± 0.067	2.183ArgLys: 2.183 ± 0.058	7.513ArgLeu: 7.513 ± 0.115	1.79ArgMet: 1.79 ± 0.036	1.934ArgAsn: 1.934 ± 0.044	3.239ArgPro: 3.239 ± 0.068	2.831ArgGln: 2.831 ± 0.059	4.861ArgArg: 4.861 ± 0.099	3.479ArgSer: 3.479 ± 0.068	3.335ArgThr: 3.335 ± 0.07	4.516ArgVal: 4.516 ± 0.071	0.836ArgTrp: 0.836 ± 0.035	1.584ArgTyr: 1.584 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.502SerAla: 6.502 ± 0.093	0.302SerCys: 0.302 ± 0.02	2.95SerAsp: 2.95 ± 0.053	2.734SerGlu: 2.734 ± 0.06	2.369SerPhe: 2.369 ± 0.052	5.738SerGly: 5.738 ± 0.123	1.113SerHis: 1.113 ± 0.039	2.945SerIle: 2.945 ± 0.061	1.46SerLys: 1.46 ± 0.041	5.624SerLeu: 5.624 ± 0.083	1.466SerMet: 1.466 ± 0.04	1.452SerAsn: 1.452 ± 0.04	2.572SerPro: 2.572 ± 0.058	1.74SerGln: 1.74 ± 0.043	3.521SerArg: 3.521 ± 0.063	2.886SerSer: 2.886 ± 0.068	2.726SerThr: 2.726 ± 0.057	4.39SerVal: 4.39 ± 0.079	0.749SerTrp: 0.749 ± 0.032	1.277SerTyr: 1.277 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	5.825ThrAla: 5.825 ± 0.079	0.322ThrCys: 0.322 ± 0.019	2.91ThrAsp: 2.91 ± 0.058	2.791ThrGlu: 2.791 ± 0.062	2.124ThrPhe: 2.124 ± 0.054	5.112ThrGly: 5.112 ± 0.087	1.085ThrHis: 1.085 ± 0.033	3.439ThrIle: 3.439 ± 0.054	1.348ThrLys: 1.348 ± 0.04	6.326ThrLeu: 6.326 ± 0.109	1.219ThrMet: 1.219 ± 0.042	1.519ThrAsn: 1.519 ± 0.045	3.035ThrPro: 3.035 ± 0.058	1.614ThrGln: 1.614 ± 0.041	3.318ThrArg: 3.318 ± 0.068	2.874ThrSer: 2.874 ± 0.063	2.839ThrThr: 2.839 ± 0.067	3.747ThrVal: 3.747 ± 0.075	0.665ThrTrp: 0.665 ± 0.024	1.204ThrTyr: 1.204 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	8.713ValAla: 8.713 ± 0.114	0.496ValCys: 0.496 ± 0.025	4.379ValAsp: 4.379 ± 0.071	4.594ValGlu: 4.594 ± 0.072	2.823ValPhe: 2.823 ± 0.061	5.748ValGly: 5.748 ± 0.088	1.412ValHis: 1.412 ± 0.038	4.279ValIle: 4.279 ± 0.076	2.074ValLys: 2.074 ± 0.054	7.996ValLeu: 7.996 ± 0.107	1.951ValMet: 1.951 ± 0.055	2.045ValAsn: 2.045 ± 0.055	3.845ValPro: 3.845 ± 0.067	2.196ValGln: 2.196 ± 0.048	4.632ValArg: 4.632 ± 0.071	4.558ValSer: 4.558 ± 0.078	4.709ValThr: 4.709 ± 0.079	6.024ValVal: 6.024 ± 0.101	0.9ValTrp: 0.9 ± 0.029	1.513ValTyr: 1.513 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.218TrpAla: 1.218 ± 0.036	0.121TrpCys: 0.121 ± 0.01	0.648TrpAsp: 0.648 ± 0.026	0.559TrpGlu: 0.559 ± 0.026	0.521TrpPhe: 0.521 ± 0.022	0.883TrpGly: 0.883 ± 0.036	0.305TrpHis: 0.305 ± 0.019	0.624TrpIle: 0.624 ± 0.026	0.393TrpLys: 0.393 ± 0.021	1.582TrpLeu: 1.582 ± 0.048	0.33TrpMet: 0.33 ± 0.018	0.464TrpAsn: 0.464 ± 0.021	0.675TrpPro: 0.675 ± 0.029	0.616TrpGln: 0.616 ± 0.023	1.012TrpArg: 1.012 ± 0.037	0.827TrpSer: 0.827 ± 0.03	0.798TrpThr: 0.798 ± 0.028	0.924TrpVal: 0.924 ± 0.035	0.225TrpTrp: 0.225 ± 0.016	0.275TrpTyr: 0.275 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.552TyrAla: 2.552 ± 0.053	0.217TyrCys: 0.217 ± 0.015	1.458TyrAsp: 1.458 ± 0.041	1.235TyrGlu: 1.235 ± 0.039	0.995TyrPhe: 0.995 ± 0.032	2.137TyrGly: 2.137 ± 0.051	0.465TyrHis: 0.465 ± 0.026	0.993TyrIle: 0.993 ± 0.029	0.578TyrLys: 0.578 ± 0.028	2.32TyrLeu: 2.32 ± 0.049	0.44TyrMet: 0.44 ± 0.021	0.62TyrAsn: 0.62 ± 0.023	1.136TyrPro: 1.136 ± 0.037	0.713TyrGln: 0.713 ± 0.029	1.663TyrArg: 1.663 ± 0.044	1.212TyrSer: 1.212 ± 0.036	1.076TyrThr: 1.076 ± 0.032	1.685TyrVal: 1.685 ± 0.045	0.356TyrTrp: 0.356 ± 0.017	0.585TyrTyr: 0.585 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3103 proteins (967854 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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