Amino acid dipepetide frequency for Micractinium conductrix

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	43.47AlaAla: 43.47 ± 0.278	2.278AlaCys: 2.278 ± 0.029	6.439AlaAsp: 6.439 ± 0.034	9.247AlaGlu: 9.247 ± 0.079	3.408AlaPhe: 3.408 ± 0.027	14.896AlaGly: 14.896 ± 0.08	2.56AlaHis: 2.56 ± 0.02	2.768AlaIle: 2.768 ± 0.027	3.786AlaLys: 3.786 ± 0.038	13.937AlaLeu: 13.937 ± 0.074	2.5AlaMet: 2.5 ± 0.021	2.198AlaAsn: 2.198 ± 0.021	10.057AlaPro: 10.057 ± 0.064	6.693AlaGln: 6.693 ± 0.056	7.998AlaArg: 7.998 ± 0.044	9.183AlaSer: 9.183 ± 0.05	6.464AlaThr: 6.464 ± 0.036	10.005AlaVal: 10.005 ± 0.05	1.787AlaTrp: 1.787 ± 0.022	2.104AlaTyr: 2.104 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	1.804CysAla: 1.804 ± 0.023	0.474CysCys: 0.474 ± 0.011	0.743CysAsp: 0.743 ± 0.013	0.716CysGlu: 0.716 ± 0.011	0.494CysPhe: 0.494 ± 0.01	1.516CysGly: 1.516 ± 0.021	0.354CysHis: 0.354 ± 0.009	0.479CysIle: 0.479 ± 0.01	0.563CysLys: 0.563 ± 0.013	1.619CysLeu: 1.619 ± 0.02	0.348CysMet: 0.348 ± 0.008	0.437CysAsn: 0.437 ± 0.008	1.029CysPro: 1.029 ± 0.026	0.621CysGln: 0.621 ± 0.013	1.137CysArg: 1.137 ± 0.016	1.24CysSer: 1.24 ± 0.018	0.995CysThr: 0.995 ± 0.016	0.994CysVal: 0.994 ± 0.013	0.291CysTrp: 0.291 ± 0.008	0.35CysTyr: 0.35 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	6.685AspAla: 6.685 ± 0.036	0.744AspCys: 0.744 ± 0.011	2.655AspAsp: 2.655 ± 0.026	3.253AspGlu: 3.253 ± 0.029	1.369AspPhe: 1.369 ± 0.018	4.522AspGly: 4.522 ± 0.029	0.696AspHis: 0.696 ± 0.011	1.391AspIle: 1.391 ± 0.019	1.431AspLys: 1.431 ± 0.02	4.11AspLeu: 4.11 ± 0.029	0.974AspMet: 0.974 ± 0.014	0.91AspAsn: 0.91 ± 0.015	2.557AspPro: 2.557 ± 0.022	1.246AspGln: 1.246 ± 0.016	2.341AspArg: 2.341 ± 0.023	2.845AspSer: 2.845 ± 0.022	1.899AspThr: 1.899 ± 0.019	3.2AspVal: 3.2 ± 0.024	0.755AspTrp: 0.755 ± 0.011	0.93AspTyr: 0.93 ± 0.014	0.0AspXaa: 0.0 ± 0.0
Glu	9.729GluAla: 9.729 ± 0.081	0.768GluCys: 0.768 ± 0.012	2.766GluAsp: 2.766 ± 0.025	6.223GluGlu: 6.223 ± 0.086	1.318GluPhe: 1.318 ± 0.016	5.241GluGly: 5.241 ± 0.032	1.175GluHis: 1.175 ± 0.013	1.187GluIle: 1.187 ± 0.013	1.684GluLys: 1.684 ± 0.025	6.1GluLeu: 6.1 ± 0.044	1.05GluMet: 1.05 ± 0.015	0.814GluAsn: 0.814 ± 0.013	2.772GluPro: 2.772 ± 0.023	3.81GluGln: 3.81 ± 0.06	4.266GluArg: 4.266 ± 0.039	2.325GluSer: 2.325 ± 0.019	1.749GluThr: 1.749 ± 0.019	3.868GluVal: 3.868 ± 0.027	0.792GluTrp: 0.792 ± 0.012	0.989GluTyr: 0.989 ± 0.014	0.0GluXaa: 0.0 ± 0.0
Phe	2.963PheAla: 2.963 ± 0.027	0.57PheCys: 0.57 ± 0.009	1.566PheAsp: 1.566 ± 0.015	1.516PheGlu: 1.516 ± 0.018	0.978PhePhe: 0.978 ± 0.014	2.373PheGly: 2.373 ± 0.032	0.586PheHis: 0.586 ± 0.011	0.8PheIle: 0.8 ± 0.013	0.997PheLys: 0.997 ± 0.014	2.421PheLeu: 2.421 ± 0.025	0.593PheMet: 0.593 ± 0.01	0.827PheAsn: 0.827 ± 0.013	1.263PhePro: 1.263 ± 0.016	0.966PheGln: 0.966 ± 0.013	1.435PheArg: 1.435 ± 0.018	1.847PheSer: 1.847 ± 0.019	1.381PheThr: 1.381 ± 0.015	1.857PheVal: 1.857 ± 0.02	0.415PheTrp: 0.415 ± 0.009	0.704PheTyr: 0.704 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	13.058GlyAla: 13.058 ± 0.069	1.421GlyCys: 1.421 ± 0.018	4.213GlyAsp: 4.213 ± 0.025	4.882GlyGlu: 4.882 ± 0.032	2.274GlyPhe: 2.274 ± 0.024	15.181GlyGly: 15.181 ± 0.115	1.594GlyHis: 1.594 ± 0.016	2.091GlyIle: 2.091 ± 0.026	3.063GlyLys: 3.063 ± 0.025	7.388GlyLeu: 7.388 ± 0.044	1.955GlyMet: 1.955 ± 0.023	1.702GlyAsn: 1.702 ± 0.021	4.112GlyPro: 4.112 ± 0.033	3.39GlyGln: 3.39 ± 0.025	5.698GlyArg: 5.698 ± 0.039	8.075GlySer: 8.075 ± 0.063	4.298GlyThr: 4.298 ± 0.035	5.433GlyVal: 5.433 ± 0.036	1.38GlyTrp: 1.38 ± 0.018	1.693GlyTyr: 1.693 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.844HisAla: 2.844 ± 0.024	0.414HisCys: 0.414 ± 0.009	0.859HisAsp: 0.859 ± 0.014	1.036HisGlu: 1.036 ± 0.013	0.648HisPhe: 0.648 ± 0.012	1.831HisGly: 1.831 ± 0.018	0.768HisHis: 0.768 ± 0.015	0.611HisIle: 0.611 ± 0.01	0.646HisLys: 0.646 ± 0.01	2.305HisLeu: 2.305 ± 0.023	0.494HisMet: 0.494 ± 0.009	0.48HisAsn: 0.48 ± 0.009	1.525HisPro: 1.525 ± 0.018	0.948HisGln: 0.948 ± 0.015	1.419HisArg: 1.419 ± 0.015	1.384HisSer: 1.384 ± 0.017	1.057HisThr: 1.057 ± 0.013	1.362HisVal: 1.362 ± 0.015	0.36HisTrp: 0.36 ± 0.007	0.489HisTyr: 0.489 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	2.676IleAla: 2.676 ± 0.026	0.445IleCys: 0.445 ± 0.01	1.456IleAsp: 1.456 ± 0.015	1.352IleGlu: 1.352 ± 0.017	0.798IlePhe: 0.798 ± 0.013	1.675IleGly: 1.675 ± 0.02	0.468IleHis: 0.468 ± 0.009	0.844IleIle: 0.844 ± 0.017	1.073IleLys: 1.073 ± 0.018	1.921IleLeu: 1.921 ± 0.021	0.554IleMet: 0.554 ± 0.01	0.772IleAsn: 0.772 ± 0.012	1.251IlePro: 1.251 ± 0.015	0.896IleGln: 0.896 ± 0.014	1.323IleArg: 1.323 ± 0.014	1.556IleSer: 1.556 ± 0.019	1.388IleThr: 1.388 ± 0.018	1.693IleVal: 1.693 ± 0.017	0.292IleTrp: 0.292 ± 0.007	0.595IleTyr: 0.595 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	4.033LysAla: 4.033 ± 0.035	0.466LysCys: 0.466 ± 0.012	1.277LysAsp: 1.277 ± 0.018	2.12LysGlu: 2.12 ± 0.027	0.72LysPhe: 0.72 ± 0.013	2.364LysGly: 2.364 ± 0.027	0.702LysHis: 0.702 ± 0.011	0.804LysIle: 0.804 ± 0.015	1.754LysLys: 1.754 ± 0.031	3.0LysLeu: 3.0 ± 0.027	0.594LysMet: 0.594 ± 0.011	0.66LysAsn: 0.66 ± 0.011	1.952LysPro: 1.952 ± 0.023	1.753LysGln: 1.753 ± 0.021	2.465LysArg: 2.465 ± 0.025	1.43LysSer: 1.43 ± 0.017	1.259LysThr: 1.259 ± 0.02	1.956LysVal: 1.956 ± 0.022	0.404LysTrp: 0.404 ± 0.009	0.699LysTyr: 0.699 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	14.336LeuAla: 14.336 ± 0.073	1.645LeuCys: 1.645 ± 0.019	4.478LeuAsp: 4.478 ± 0.029	5.765LeuGlu: 5.765 ± 0.041	2.608LeuPhe: 2.608 ± 0.024	7.287LeuGly: 7.287 ± 0.043	2.585LeuHis: 2.585 ± 0.025	1.98LeuIle: 1.98 ± 0.022	2.837LeuLys: 2.837 ± 0.027	12.038LeuLeu: 12.038 ± 0.088	1.739LeuMet: 1.739 ± 0.019	1.881LeuAsn: 1.881 ± 0.018	7.54LeuPro: 7.54 ± 0.052	5.782LeuGln: 5.782 ± 0.044	7.57LeuArg: 7.57 ± 0.041	6.087LeuSer: 6.087 ± 0.034	4.359LeuThr: 4.359 ± 0.031	6.001LeuVal: 6.001 ± 0.036	1.247LeuTrp: 1.247 ± 0.015	1.79LeuTyr: 1.79 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	2.628MetAla: 2.628 ± 0.022	0.261MetCys: 0.261 ± 0.006	0.845MetAsp: 0.845 ± 0.012	1.093MetGlu: 1.093 ± 0.014	0.481MetPhe: 0.481 ± 0.009	1.481MetGly: 1.481 ± 0.019	0.517MetHis: 0.517 ± 0.01	0.403MetIle: 0.403 ± 0.008	0.546MetLys: 0.546 ± 0.009	2.122MetLeu: 2.122 ± 0.02	0.418MetMet: 0.418 ± 0.01	0.362MetAsn: 0.362 ± 0.008	1.328MetPro: 1.328 ± 0.018	1.209MetGln: 1.209 ± 0.016	1.372MetArg: 1.372 ± 0.017	1.108MetSer: 1.108 ± 0.015	0.754MetThr: 0.754 ± 0.012	1.167MetVal: 1.167 ± 0.015	0.238MetTrp: 0.238 ± 0.007	0.357MetTyr: 0.357 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.263AsnAla: 2.263 ± 0.021	0.4AsnCys: 0.4 ± 0.009	0.829AsnAsp: 0.829 ± 0.014	0.935AsnGlu: 0.935 ± 0.013	0.648AsnPhe: 0.648 ± 0.011	1.809AsnGly: 1.809 ± 0.019	0.352AsnHis: 0.352 ± 0.008	0.725AsnIle: 0.725 ± 0.012	0.789AsnLys: 0.789 ± 0.014	1.795AsnLeu: 1.795 ± 0.019	0.445AsnMet: 0.445 ± 0.009	0.552AsnAsn: 0.552 ± 0.01	1.278AsnPro: 1.278 ± 0.016	0.622AsnGln: 0.622 ± 0.009	1.12AsnArg: 1.12 ± 0.015	1.267AsnSer: 1.267 ± 0.013	1.025AsnThr: 1.025 ± 0.015	1.321AsnVal: 1.321 ± 0.016	0.326AsnTrp: 0.326 ± 0.006	0.476AsnTyr: 0.476 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	11.87ProAla: 11.87 ± 0.086	0.823ProCys: 0.823 ± 0.017	2.657ProAsp: 2.657 ± 0.023	3.364ProGlu: 3.364 ± 0.024	1.501ProPhe: 1.501 ± 0.017	5.922ProGly: 5.922 ± 0.045	1.304ProHis: 1.304 ± 0.016	1.149ProIle: 1.149 ± 0.014	1.613ProLys: 1.613 ± 0.02	6.092ProLeu: 6.092 ± 0.043	0.925ProMet: 0.925 ± 0.013	1.045ProAsn: 1.045 ± 0.014	7.755ProPro: 7.755 ± 0.084	2.889ProGln: 2.889 ± 0.029	3.748ProArg: 3.748 ± 0.032	4.727ProSer: 4.727 ± 0.041	3.08ProThr: 3.08 ± 0.026	3.499ProVal: 3.499 ± 0.026	0.774ProTrp: 0.774 ± 0.01	0.983ProTyr: 0.983 ± 0.012	0.0ProXaa: 0.0 ± 0.0
Gln	7.254GlnAla: 7.254 ± 0.056	0.568GlnCys: 0.568 ± 0.013	1.5GlnAsp: 1.5 ± 0.017	2.987GlnGlu: 2.987 ± 0.052	1.005GlnPhe: 1.005 ± 0.013	3.299GlnGly: 3.299 ± 0.026	1.744GlnHis: 1.744 ± 0.022	0.846GlnIle: 0.846 ± 0.012	1.154GlnLys: 1.154 ± 0.015	6.181GlnLeu: 6.181 ± 0.042	0.831GlnMet: 0.831 ± 0.013	0.579GlnAsn: 0.579 ± 0.01	3.889GlnPro: 3.889 ± 0.038	9.733GlnGln: 9.733 ± 0.147	4.785GlnArg: 4.785 ± 0.036	1.771GlnSer: 1.771 ± 0.018	1.413GlnThr: 1.413 ± 0.015	2.509GlnVal: 2.509 ± 0.017	0.609GlnTrp: 0.609 ± 0.011	0.845GlnTyr: 0.845 ± 0.013	0.0GlnXaa: 0.0 ± 0.0
Arg	7.826ArgAla: 7.826 ± 0.039	1.267ArgCys: 1.267 ± 0.017	2.634ArgAsp: 2.634 ± 0.025	3.444ArgGlu: 3.444 ± 0.035	1.797ArgPhe: 1.797 ± 0.021	5.302ArgGly: 5.302 ± 0.033	1.733ArgHis: 1.733 ± 0.019	1.607ArgIle: 1.607 ± 0.02	2.205ArgLys: 2.205 ± 0.021	7.468ArgLeu: 7.468 ± 0.04	1.299ArgMet: 1.299 ± 0.014	1.229ArgAsn: 1.229 ± 0.015	3.922ArgPro: 3.922 ± 0.031	4.18ArgGln: 4.18 ± 0.033	6.743ArgArg: 6.743 ± 0.05	4.347ArgSer: 4.347 ± 0.032	2.674ArgThr: 2.674 ± 0.024	3.843ArgVal: 3.843 ± 0.024	1.095ArgTrp: 1.095 ± 0.013	1.343ArgTyr: 1.343 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	8.499SerAla: 8.499 ± 0.048	1.023SerCys: 1.023 ± 0.018	2.95SerAsp: 2.95 ± 0.023	3.045SerGlu: 3.045 ± 0.025	1.833SerPhe: 1.833 ± 0.02	7.102SerGly: 7.102 ± 0.046	1.129SerHis: 1.129 ± 0.014	1.593SerIle: 1.593 ± 0.018	1.981SerLys: 1.981 ± 0.02	6.217SerLeu: 6.217 ± 0.042	1.31SerMet: 1.31 ± 0.015	1.391SerAsn: 1.391 ± 0.016	4.569SerPro: 4.569 ± 0.051	2.338SerGln: 2.338 ± 0.02	3.763SerArg: 3.763 ± 0.028	6.213SerSer: 6.213 ± 0.059	3.163SerThr: 3.163 ± 0.027	3.699SerVal: 3.699 ± 0.029	0.934SerTrp: 0.934 ± 0.013	1.214SerTyr: 1.214 ± 0.017	0.0SerXaa: 0.0 ± 0.0
Thr	6.89ThrAla: 6.89 ± 0.039	0.847ThrCys: 0.847 ± 0.017	1.854ThrAsp: 1.854 ± 0.019	1.954ThrGlu: 1.954 ± 0.016	1.382ThrPhe: 1.382 ± 0.018	3.728ThrGly: 3.728 ± 0.028	0.907ThrHis: 0.907 ± 0.013	1.332ThrIle: 1.332 ± 0.019	1.274ThrLys: 1.274 ± 0.02	4.581ThrLeu: 4.581 ± 0.03	0.756ThrMet: 0.756 ± 0.011	0.956ThrAsn: 0.956 ± 0.014	3.344ThrPro: 3.344 ± 0.031	1.703ThrGln: 1.703 ± 0.016	2.359ThrArg: 2.359 ± 0.02	2.99ThrSer: 2.99 ± 0.022	2.244ThrThr: 2.244 ± 0.027	3.087ThrVal: 3.087 ± 0.026	0.618ThrTrp: 0.618 ± 0.01	0.957ThrTyr: 0.957 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	9.431ValAla: 9.431 ± 0.051	1.06ValCys: 1.06 ± 0.015	3.062ValAsp: 3.062 ± 0.024	3.858ValGlu: 3.858 ± 0.028	1.746ValPhe: 1.746 ± 0.02	4.64ValGly: 4.64 ± 0.03	1.485ValHis: 1.485 ± 0.015	1.499ValIle: 1.499 ± 0.019	1.946ValLys: 1.946 ± 0.018	6.899ValLeu: 6.899 ± 0.04	1.201ValMet: 1.201 ± 0.015	1.249ValAsn: 1.249 ± 0.015	4.045ValPro: 4.045 ± 0.032	3.067ValGln: 3.067 ± 0.024	3.891ValArg: 3.891 ± 0.024	3.444ValSer: 3.444 ± 0.026	3.011ValThr: 3.011 ± 0.029	4.97ValVal: 4.97 ± 0.045	0.854ValTrp: 0.854 ± 0.012	1.22ValTyr: 1.22 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	1.53TrpAla: 1.53 ± 0.018	0.265TrpCys: 0.265 ± 0.007	0.686TrpAsp: 0.686 ± 0.011	0.843TrpGlu: 0.843 ± 0.012	0.361TrpPhe: 0.361 ± 0.007	1.084TrpGly: 1.084 ± 0.015	0.377TrpHis: 0.377 ± 0.008	0.287TrpIle: 0.287 ± 0.007	0.394TrpLys: 0.394 ± 0.009	1.547TrpLeu: 1.547 ± 0.018	0.298TrpMet: 0.298 ± 0.007	0.346TrpAsn: 0.346 ± 0.007	0.679TrpPro: 0.679 ± 0.011	0.942TrpGln: 0.942 ± 0.013	1.303TrpArg: 1.303 ± 0.017	0.81TrpSer: 0.81 ± 0.012	0.568TrpThr: 0.568 ± 0.01	0.873TrpVal: 0.873 ± 0.013	0.282TrpTrp: 0.282 ± 0.007	0.273TrpTyr: 0.273 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.988TyrAla: 1.988 ± 0.02	0.464TyrCys: 0.464 ± 0.01	1.042TyrAsp: 1.042 ± 0.013	0.993TyrGlu: 0.993 ± 0.015	0.688TyrPhe: 0.688 ± 0.012	1.646TyrGly: 1.646 ± 0.022	0.443TyrHis: 0.443 ± 0.008	0.633TyrIle: 0.633 ± 0.01	0.672TyrLys: 0.672 ± 0.013	1.815TyrLeu: 1.815 ± 0.019	0.41TyrMet: 0.41 ± 0.009	0.586TyrAsn: 0.586 ± 0.011	0.859TyrPro: 0.859 ± 0.015	0.715TyrGln: 0.715 ± 0.01	1.222TyrArg: 1.222 ± 0.015	1.318TyrSer: 1.318 ± 0.017	0.982TyrThr: 0.982 ± 0.015	1.242TyrVal: 1.242 ± 0.015	0.295TyrTrp: 0.295 ± 0.008	0.533TyrTyr: 0.533 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9815 proteins (6408442 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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