Amino acid dipepetide frequency for Capnocytophaga ochracea (strain ATCC 27872 / DSM 7271 / JCM 12966 / NCTC 12371 / VPI 2845) (Bacteroides ochraceus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.444AlaAla: 3.444 ± 0.083
0.687AlaCys: 0.687 ± 0.035
3.487AlaAsp: 3.487 ± 0.077
4.691AlaGlu: 4.691 ± 0.087
3.614AlaPhe: 3.614 ± 0.066
4.384AlaGly: 4.384 ± 0.102
1.369AlaHis: 1.369 ± 0.045
5.3AlaIle: 5.3 ± 0.088
5.065AlaLys: 5.065 ± 0.093
7.375AlaLeu: 7.375 ± 0.126
1.727AlaMet: 1.727 ± 0.053
3.571AlaAsn: 3.571 ± 0.073
2.397AlaPro: 2.397 ± 0.066
3.376AlaGln: 3.376 ± 0.073
2.355AlaArg: 2.355 ± 0.061
4.076AlaSer: 4.076 ± 0.077
4.827AlaThr: 4.827 ± 0.145
4.387AlaVal: 4.387 ± 0.08
0.611AlaTrp: 0.611 ± 0.027
2.947AlaTyr: 2.947 ± 0.067
0.0AlaXaa: 0.0 ± 0.0
Cys
0.52CysAla: 0.52 ± 0.032
0.085CysCys: 0.085 ± 0.012
0.406CysAsp: 0.406 ± 0.028
0.544CysGlu: 0.544 ± 0.03
0.45CysPhe: 0.45 ± 0.027
0.658CysGly: 0.658 ± 0.042
0.206CysHis: 0.206 ± 0.021
0.544CysIle: 0.544 ± 0.027
0.538CysLys: 0.538 ± 0.025
0.701CysLeu: 0.701 ± 0.031
0.155CysMet: 0.155 ± 0.014
0.443CysAsn: 0.443 ± 0.03
0.326CysPro: 0.326 ± 0.027
0.271CysGln: 0.271 ± 0.02
0.238CysArg: 0.238 ± 0.018
0.547CysSer: 0.547 ± 0.031
0.495CysThr: 0.495 ± 0.034
0.516CysVal: 0.516 ± 0.031
0.087CysTrp: 0.087 ± 0.011
0.403CysTyr: 0.403 ± 0.024
0.0CysXaa: 0.0 ± 0.0
Asp
3.473AspAla: 3.473 ± 0.075
0.406AspCys: 0.406 ± 0.031
2.442AspAsp: 2.442 ± 0.063
3.521AspGlu: 3.521 ± 0.083
3.266AspPhe: 3.266 ± 0.075
3.164AspGly: 3.164 ± 0.083
0.639AspHis: 0.639 ± 0.031
3.905AspIle: 3.905 ± 0.072
4.249AspLys: 4.249 ± 0.073
4.417AspLeu: 4.417 ± 0.081
1.129AspMet: 1.129 ± 0.044
2.827AspAsn: 2.827 ± 0.06
1.74AspPro: 1.74 ± 0.05
0.993AspGln: 0.993 ± 0.037
1.839AspArg: 1.839 ± 0.045
2.594AspSer: 2.594 ± 0.06
2.837AspThr: 2.837 ± 0.061
3.119AspVal: 3.119 ± 0.07
0.705AspTrp: 0.705 ± 0.033
2.724AspTyr: 2.724 ± 0.058
0.0AspXaa: 0.0 ± 0.0
Glu
5.222GluAla: 5.222 ± 0.092
0.407GluCys: 0.407 ± 0.024
2.931GluAsp: 2.931 ± 0.077
5.296GluGlu: 5.296 ± 0.103
2.408GluPhe: 2.408 ± 0.061
4.293GluGly: 4.293 ± 0.069
1.242GluHis: 1.242 ± 0.045
4.57GluIle: 4.57 ± 0.1
5.915GluLys: 5.915 ± 0.126
6.007GluLeu: 6.007 ± 0.102
1.555GluMet: 1.555 ± 0.044
3.892GluAsn: 3.892 ± 0.081
1.667GluPro: 1.667 ± 0.045
2.853GluGln: 2.853 ± 0.073
3.232GluArg: 3.232 ± 0.073
2.853GluSer: 2.853 ± 0.067
3.414GluThr: 3.414 ± 0.061
5.237GluVal: 5.237 ± 0.091
0.707GluTrp: 0.707 ± 0.031
2.622GluTyr: 2.622 ± 0.065
0.0GluXaa: 0.0 ± 0.0
Phe
3.378PheAla: 3.378 ± 0.075
0.47PheCys: 0.47 ± 0.03
2.696PheAsp: 2.696 ± 0.068
3.056PheGlu: 3.056 ± 0.069
2.634PhePhe: 2.634 ± 0.071
3.171PheGly: 3.171 ± 0.077
0.855PheHis: 0.855 ± 0.037
3.461PheIle: 3.461 ± 0.1
3.22PheLys: 3.22 ± 0.067
4.631PheLeu: 4.631 ± 0.112
1.134PheMet: 1.134 ± 0.043
2.629PheAsn: 2.629 ± 0.065
1.811PhePro: 1.811 ± 0.043
1.555PheGln: 1.555 ± 0.047
1.779PheArg: 1.779 ± 0.046
3.707PheSer: 3.707 ± 0.081
3.194PheThr: 3.194 ± 0.076
3.136PheVal: 3.136 ± 0.087
0.578PheTrp: 0.578 ± 0.031
2.202PheTyr: 2.202 ± 0.056
0.0PheXaa: 0.0 ± 0.0
Gly
4.471GlyAla: 4.471 ± 0.09
0.642GlyCys: 0.642 ± 0.058
3.144GlyAsp: 3.144 ± 0.065
3.908GlyGlu: 3.908 ± 0.068
3.222GlyPhe: 3.222 ± 0.074
4.75GlyGly: 4.75 ± 0.133
1.121GlyHis: 1.121 ± 0.047
4.848GlyIle: 4.848 ± 0.09
5.618GlyLys: 5.618 ± 0.099
5.23GlyLeu: 5.23 ± 0.103
1.511GlyMet: 1.511 ± 0.05
3.658GlyAsn: 3.658 ± 0.095
0.75GlyPro: 0.75 ± 0.035
1.878GlyGln: 1.878 ± 0.06
2.362GlyArg: 2.362 ± 0.062
3.565GlySer: 3.565 ± 0.084
4.176GlyThr: 4.176 ± 0.15
4.937GlyVal: 4.937 ± 0.087
0.793GlyTrp: 0.793 ± 0.034
3.09GlyTyr: 3.09 ± 0.074
0.0GlyXaa: 0.0 ± 0.0
His
0.821HisAla: 0.821 ± 0.039
0.234HisCys: 0.234 ± 0.018
0.63HisAsp: 0.63 ± 0.03
0.779HisGlu: 0.779 ± 0.035
1.221HisPhe: 1.221 ± 0.045
0.941HisGly: 0.941 ± 0.036
0.464HisHis: 0.464 ± 0.029
1.672HisIle: 1.672 ± 0.051
1.34HisLys: 1.34 ± 0.039
2.133HisLeu: 2.133 ± 0.062
0.188HisMet: 0.188 ± 0.017
1.15HisAsn: 1.15 ± 0.042
0.982HisPro: 0.982 ± 0.037
0.838HisGln: 0.838 ± 0.035
0.883HisArg: 0.883 ± 0.038
1.205HisSer: 1.205 ± 0.038
1.32HisThr: 1.32 ± 0.038
0.701HisVal: 0.701 ± 0.033
0.286HisTrp: 0.286 ± 0.02
1.02HisTyr: 1.02 ± 0.035
0.0HisXaa: 0.0 ± 0.0
Ile
6.072IleAla: 6.072 ± 0.091
0.597IleCys: 0.597 ± 0.028
4.264IleAsp: 4.264 ± 0.072
4.994IleGlu: 4.994 ± 0.082
3.228IlePhe: 3.228 ± 0.078
5.01IleGly: 5.01 ± 0.089
1.254IleHis: 1.254 ± 0.044
4.774IleIle: 4.774 ± 0.107
4.88IleLys: 4.88 ± 0.085
5.901IleLeu: 5.901 ± 0.119
1.126IleMet: 1.126 ± 0.038
3.523IleAsn: 3.523 ± 0.076
3.191IlePro: 3.191 ± 0.07
2.339IleGln: 2.339 ± 0.057
2.698IleArg: 2.698 ± 0.063
4.758IleSer: 4.758 ± 0.085
5.145IleThr: 5.145 ± 0.13
4.64IleVal: 4.64 ± 0.083
0.61IleTrp: 0.61 ± 0.028
2.646IleTyr: 2.646 ± 0.066
0.0IleXaa: 0.0 ± 0.0
Lys
5.564LysAla: 5.564 ± 0.093
0.348LysCys: 0.348 ± 0.02
4.391LysAsp: 4.391 ± 0.077
6.637LysGlu: 6.637 ± 0.129
2.338LysPhe: 2.338 ± 0.058
5.282LysGly: 5.282 ± 0.094
1.448LysHis: 1.448 ± 0.044
5.13LysIle: 5.13 ± 0.093
6.359LysLys: 6.359 ± 0.111
5.981LysLeu: 5.981 ± 0.1
1.92LysMet: 1.92 ± 0.059
4.579LysAsn: 4.579 ± 0.075
2.504LysPro: 2.504 ± 0.071
3.065LysGln: 3.065 ± 0.066
3.16LysArg: 3.16 ± 0.075
3.659LysSer: 3.659 ± 0.065
4.56LysThr: 4.56 ± 0.077
5.229LysVal: 5.229 ± 0.086
0.749LysTrp: 0.749 ± 0.035
3.202LysTyr: 3.202 ± 0.074
0.0LysXaa: 0.0 ± 0.0
Leu
6.354LeuAla: 6.354 ± 0.115
0.842LeuCys: 0.842 ± 0.036
4.06LeuAsp: 4.06 ± 0.083
5.213LeuGlu: 5.213 ± 0.081
4.85LeuPhe: 4.85 ± 0.116
5.486LeuGly: 5.486 ± 0.093
1.867LeuHis: 1.867 ± 0.054
6.298LeuIle: 6.298 ± 0.116
7.183LeuLys: 7.183 ± 0.113
9.649LeuLeu: 9.649 ± 0.189
1.884LeuMet: 1.884 ± 0.054
5.043LeuAsn: 5.043 ± 0.087
4.086LeuPro: 4.086 ± 0.094
4.133LeuGln: 4.133 ± 0.084
3.767LeuArg: 3.767 ± 0.072
6.986LeuSer: 6.986 ± 0.108
5.828LeuThr: 5.828 ± 0.098
5.13LeuVal: 5.13 ± 0.087
1.038LeuTrp: 1.038 ± 0.049
3.675LeuTyr: 3.675 ± 0.072
0.0LeuXaa: 0.0 ± 0.0
Met
1.588MetAla: 1.588 ± 0.047
0.151MetCys: 0.151 ± 0.015
0.974MetAsp: 0.974 ± 0.04
1.317MetGlu: 1.317 ± 0.051
0.73MetPhe: 0.73 ± 0.032
1.487MetGly: 1.487 ± 0.052
0.403MetHis: 0.403 ± 0.026
1.311MetIle: 1.311 ± 0.045
2.225MetLys: 2.225 ± 0.058
2.083MetLeu: 2.083 ± 0.057
0.551MetMet: 0.551 ± 0.026
1.325MetAsn: 1.325 ± 0.043
0.909MetPro: 0.909 ± 0.034
0.941MetGln: 0.941 ± 0.037
1.024MetArg: 1.024 ± 0.037
1.202MetSer: 1.202 ± 0.043
1.074MetThr: 1.074 ± 0.043
1.287MetVal: 1.287 ± 0.039
0.202MetTrp: 0.202 ± 0.018
0.719MetTyr: 0.719 ± 0.034
0.0MetXaa: 0.0 ± 0.0
Asn
3.916AsnAla: 3.916 ± 0.079
0.436AsnCys: 0.436 ± 0.036
2.747AsnAsp: 2.747 ± 0.068
3.414AsnGlu: 3.414 ± 0.067
2.574AsnPhe: 2.574 ± 0.061
3.662AsnGly: 3.662 ± 0.096
0.986AsnHis: 0.986 ± 0.038
4.275AsnIle: 4.275 ± 0.086
3.974AsnLys: 3.974 ± 0.072
4.714AsnLeu: 4.714 ± 0.091
1.045AsnMet: 1.045 ± 0.043
3.319AsnAsn: 3.319 ± 0.082
2.792AsnPro: 2.792 ± 0.081
1.839AsnGln: 1.839 ± 0.057
2.225AsnArg: 2.225 ± 0.063
2.936AsnSer: 2.936 ± 0.073
3.697AsnThr: 3.697 ± 0.082
3.372AsnVal: 3.372 ± 0.08
0.599AsnTrp: 0.599 ± 0.028
2.709AsnTyr: 2.709 ± 0.067
0.0AsnXaa: 0.0 ± 0.0
Pro
2.412ProAla: 2.412 ± 0.081
0.239ProCys: 0.239 ± 0.019
1.998ProAsp: 1.998 ± 0.05
2.911ProGlu: 2.911 ± 0.072
2.023ProPhe: 2.023 ± 0.058
1.319ProGly: 1.319 ± 0.059
0.757ProHis: 0.757 ± 0.034
2.937ProIle: 2.937 ± 0.061
2.789ProLys: 2.789 ± 0.064
3.427ProLeu: 3.427 ± 0.068
0.839ProMet: 0.839 ± 0.039
2.441ProAsn: 2.441 ± 0.056
1.032ProPro: 1.032 ± 0.044
1.608ProGln: 1.608 ± 0.048
1.058ProArg: 1.058 ± 0.038
2.29ProSer: 2.29 ± 0.063
2.585ProThr: 2.585 ± 0.092
2.217ProVal: 2.217 ± 0.055
0.33ProTrp: 0.33 ± 0.021
1.806ProTyr: 1.806 ± 0.049
0.0ProXaa: 0.0 ± 0.0
Gln
2.648GlnAla: 2.648 ± 0.068
0.231GlnCys: 0.231 ± 0.019
1.449GlnAsp: 1.449 ± 0.048
2.533GlnGlu: 2.533 ± 0.06
1.623GlnPhe: 1.623 ± 0.053
2.201GlnGly: 2.201 ± 0.054
0.837GlnHis: 0.837 ± 0.037
2.536GlnIle: 2.536 ± 0.056
3.22GlnLys: 3.22 ± 0.075
3.941GlnLeu: 3.941 ± 0.083
1.016GlnMet: 1.016 ± 0.034
2.079GlnAsn: 2.079 ± 0.06
1.301GlnPro: 1.301 ± 0.048
2.249GlnGln: 2.249 ± 0.076
1.716GlnArg: 1.716 ± 0.059
1.918GlnSer: 1.918 ± 0.055
2.374GlnThr: 2.374 ± 0.066
2.329GlnVal: 2.329 ± 0.055
0.631GlnTrp: 0.631 ± 0.033
1.839GlnTyr: 1.839 ± 0.056
0.0GlnXaa: 0.0 ± 0.0
Arg
2.598ArgAla: 2.598 ± 0.053
0.26ArgCys: 0.26 ± 0.019
1.734ArgAsp: 1.734 ± 0.053
2.709ArgGlu: 2.709 ± 0.072
1.994ArgPhe: 1.994 ± 0.056
2.214ArgGly: 2.214 ± 0.058
0.723ArgHis: 0.723 ± 0.033
3.13ArgIle: 3.13 ± 0.063
3.04ArgLys: 3.04 ± 0.069
3.789ArgLeu: 3.789 ± 0.081
1.016ArgMet: 1.016 ± 0.034
2.189ArgAsn: 2.189 ± 0.048
1.371ArgPro: 1.371 ± 0.042
1.284ArgGln: 1.284 ± 0.042
1.659ArgArg: 1.659 ± 0.054
1.871ArgSer: 1.871 ± 0.048
2.413ArgThr: 2.413 ± 0.06
2.47ArgVal: 2.47 ± 0.064
0.498ArgTrp: 0.498 ± 0.029
1.915ArgTyr: 1.915 ± 0.06
0.0ArgXaa: 0.0 ± 0.0
Ser
4.012SerAla: 4.012 ± 0.087
0.546SerCys: 0.546 ± 0.031
2.893SerAsp: 2.893 ± 0.065
3.574SerGlu: 3.574 ± 0.068
3.453SerPhe: 3.453 ± 0.072
3.894SerGly: 3.894 ± 0.085
1.048SerHis: 1.048 ± 0.037
4.144SerIle: 4.144 ± 0.085
4.088SerLys: 4.088 ± 0.062
5.696SerLeu: 5.696 ± 0.101
1.108SerMet: 1.108 ± 0.045
3.049SerAsn: 3.049 ± 0.069
2.169SerPro: 2.169 ± 0.055
1.991SerGln: 1.991 ± 0.057
1.891SerArg: 1.891 ± 0.051
3.4SerSer: 3.4 ± 0.076
3.29SerThr: 3.29 ± 0.098
4.293SerVal: 4.293 ± 0.092
0.65SerTrp: 0.65 ± 0.033
2.849SerTyr: 2.849 ± 0.074
0.0SerXaa: 0.0 ± 0.0
Thr
4.572ThrAla: 4.572 ± 0.124
0.448ThrCys: 0.448 ± 0.036
3.686ThrAsp: 3.686 ± 0.08
3.949ThrGlu: 3.949 ± 0.076
3.33ThrPhe: 3.33 ± 0.083
3.948ThrGly: 3.948 ± 0.123
1.34ThrHis: 1.34 ± 0.04
4.575ThrIle: 4.575 ± 0.137
3.663ThrLys: 3.663 ± 0.074
6.259ThrLeu: 6.259 ± 0.102
1.145ThrMet: 1.145 ± 0.046
3.021ThrAsn: 3.021 ± 0.084
3.482ThrPro: 3.482 ± 0.107
2.562ThrGln: 2.562 ± 0.069
1.911ThrArg: 1.911 ± 0.051
3.355ThrSer: 3.355 ± 0.082
4.153ThrThr: 4.153 ± 0.154
4.153ThrVal: 4.153 ± 0.165
0.499ThrTrp: 0.499 ± 0.027
2.995ThrTyr: 2.995 ± 0.101
0.0ThrXaa: 0.0 ± 0.0
Val
5.057ValAla: 5.057 ± 0.092
0.617ValCys: 0.617 ± 0.035
3.049ValAsp: 3.049 ± 0.073
3.826ValGlu: 3.826 ± 0.071
3.264ValPhe: 3.264 ± 0.073
4.223ValGly: 4.223 ± 0.082
1.032ValHis: 1.032 ± 0.043
4.499ValIle: 4.499 ± 0.082
4.799ValLys: 4.799 ± 0.08
6.294ValLeu: 6.294 ± 0.107
1.413ValMet: 1.413 ± 0.054
3.267ValAsn: 3.267 ± 0.068
2.505ValPro: 2.505 ± 0.065
2.302ValGln: 2.302 ± 0.059
2.668ValArg: 2.668 ± 0.066
4.084ValSer: 4.084 ± 0.086
4.122ValThr: 4.122 ± 0.172
4.808ValVal: 4.808 ± 0.105
0.618ValTrp: 0.618 ± 0.033
2.641ValTyr: 2.641 ± 0.062
0.0ValXaa: 0.0 ± 0.0
Trp
0.731TrpAla: 0.731 ± 0.031
0.101TrpCys: 0.101 ± 0.012
0.597TrpAsp: 0.597 ± 0.031
0.737TrpGlu: 0.737 ± 0.037
0.585TrpPhe: 0.585 ± 0.032
0.779TrpGly: 0.779 ± 0.033
0.306TrpHis: 0.306 ± 0.021
0.686TrpIle: 0.686 ± 0.036
0.741TrpLys: 0.741 ± 0.031
1.133TrpLeu: 1.133 ± 0.045
0.208TrpMet: 0.208 ± 0.017
0.558TrpAsn: 0.558 ± 0.03
0.143TrpPro: 0.143 ± 0.016
0.643TrpGln: 0.643 ± 0.03
0.464TrpArg: 0.464 ± 0.024
0.52TrpSer: 0.52 ± 0.029
0.535TrpThr: 0.535 ± 0.029
0.775TrpVal: 0.775 ± 0.037
0.153TrpTrp: 0.153 ± 0.018
0.46TrpTyr: 0.46 ± 0.028
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.839TyrAla: 2.839 ± 0.069
0.386TyrCys: 0.386 ± 0.027
2.412TyrAsp: 2.412 ± 0.062
2.714TyrGlu: 2.714 ± 0.065
2.492TyrPhe: 2.492 ± 0.065
2.807TyrGly: 2.807 ± 0.073
0.91TyrHis: 0.91 ± 0.036
3.06TyrIle: 3.06 ± 0.066
3.199TyrLys: 3.199 ± 0.061
4.013TyrLeu: 4.013 ± 0.09
0.83TyrMet: 0.83 ± 0.034
2.666TyrAsn: 2.666 ± 0.066
1.86TyrPro: 1.86 ± 0.05
1.948TyrGln: 1.948 ± 0.055
1.946TyrArg: 1.946 ± 0.06
2.509TyrSer: 2.509 ± 0.062
3.008TyrThr: 3.008 ± 0.092
2.351TyrVal: 2.351 ± 0.062
0.514TyrTrp: 0.514 ± 0.025
2.169TyrTyr: 2.169 ± 0.058
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2171 proteins (749313 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski