Amino acid dipepetide frequency for Pestalotiopsis fici (strain W106-1 / CGMCC3.15140)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.889AlaAla: 9.889 ± 0.053	1.14AlaCys: 1.14 ± 0.015	4.578AlaAsp: 4.578 ± 0.03	5.113AlaGlu: 5.113 ± 0.029	3.238AlaPhe: 3.238 ± 0.025	6.066AlaGly: 6.066 ± 0.031	1.797AlaHis: 1.797 ± 0.017	4.56AlaIle: 4.56 ± 0.028	4.074AlaLys: 4.074 ± 0.028	7.927AlaLeu: 7.927 ± 0.04	2.062AlaMet: 2.062 ± 0.016	3.141AlaAsn: 3.141 ± 0.022	4.579AlaPro: 4.579 ± 0.032	3.534AlaGln: 3.534 ± 0.026	4.686AlaArg: 4.686 ± 0.028	7.421AlaSer: 7.421 ± 0.041	5.706AlaThr: 5.706 ± 0.029	5.593AlaVal: 5.593 ± 0.026	1.303AlaTrp: 1.303 ± 0.014	2.31AlaTyr: 2.31 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	1.007CysAla: 1.007 ± 0.012	0.251CysCys: 0.251 ± 0.006	0.716CysAsp: 0.716 ± 0.011	0.601CysGlu: 0.601 ± 0.009	0.552CysPhe: 0.552 ± 0.009	0.966CysGly: 0.966 ± 0.013	0.331CysHis: 0.331 ± 0.007	0.772CysIle: 0.772 ± 0.01	0.488CysLys: 0.488 ± 0.009	1.292CysLeu: 1.292 ± 0.017	0.277CysMet: 0.277 ± 0.006	0.473CysAsn: 0.473 ± 0.008	0.65CysPro: 0.65 ± 0.012	0.48CysGln: 0.48 ± 0.009	0.717CysArg: 0.717 ± 0.01	0.966CysSer: 0.966 ± 0.012	0.735CysThr: 0.735 ± 0.012	0.795CysVal: 0.795 ± 0.012	0.217CysTrp: 0.217 ± 0.005	0.383CysTyr: 0.383 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.064AspAla: 5.064 ± 0.03	0.691AspCys: 0.691 ± 0.01	4.505AspAsp: 4.505 ± 0.041	4.411AspGlu: 4.411 ± 0.028	2.385AspPhe: 2.385 ± 0.02	4.333AspGly: 4.333 ± 0.027	1.347AspHis: 1.347 ± 0.014	3.161AspIle: 3.161 ± 0.022	2.457AspLys: 2.457 ± 0.021	5.223AspLeu: 5.223 ± 0.029	1.358AspMet: 1.358 ± 0.015	2.016AspAsn: 2.016 ± 0.015	3.224AspPro: 3.224 ± 0.022	2.035AspGln: 2.035 ± 0.015	2.967AspArg: 2.967 ± 0.03	4.186AspSer: 4.186 ± 0.025	3.085AspThr: 3.085 ± 0.025	3.801AspVal: 3.801 ± 0.024	1.03AspTrp: 1.03 ± 0.011	1.739AspTyr: 1.739 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.401GluAla: 5.401 ± 0.03	0.644GluCys: 0.644 ± 0.009	4.071GluAsp: 4.071 ± 0.027	4.736GluGlu: 4.736 ± 0.038	1.941GluPhe: 1.941 ± 0.019	3.425GluGly: 3.425 ± 0.024	1.426GluHis: 1.426 ± 0.016	3.027GluIle: 3.027 ± 0.021	3.39GluLys: 3.39 ± 0.028	5.13GluLeu: 5.13 ± 0.035	1.396GluMet: 1.396 ± 0.014	2.234GluAsn: 2.234 ± 0.017	2.701GluPro: 2.701 ± 0.024	2.449GluGln: 2.449 ± 0.023	3.522GluArg: 3.522 ± 0.029	4.274GluSer: 4.274 ± 0.026	3.53GluThr: 3.53 ± 0.025	3.439GluVal: 3.439 ± 0.022	0.899GluTrp: 0.899 ± 0.011	1.673GluTyr: 1.673 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	3.217PheAla: 3.217 ± 0.022	0.571PheCys: 0.571 ± 0.009	2.43PheAsp: 2.43 ± 0.019	2.164PheGlu: 2.164 ± 0.019	1.64PhePhe: 1.64 ± 0.019	3.02PheGly: 3.02 ± 0.024	0.884PheHis: 0.884 ± 0.01	1.882PheIle: 1.882 ± 0.017	1.504PheLys: 1.504 ± 0.015	3.482PheLeu: 3.482 ± 0.024	0.861PheMet: 0.861 ± 0.01	1.453PheAsn: 1.453 ± 0.017	1.889PhePro: 1.889 ± 0.018	1.435PheGln: 1.435 ± 0.015	1.941PheArg: 1.941 ± 0.016	2.951PheSer: 2.951 ± 0.02	2.185PheThr: 2.185 ± 0.019	2.47PheVal: 2.47 ± 0.021	0.716PheTrp: 0.716 ± 0.01	1.134PheTyr: 1.134 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	5.668GlyAla: 5.668 ± 0.031	0.923GlyCys: 0.923 ± 0.012	3.781GlyAsp: 3.781 ± 0.026	3.361GlyGlu: 3.361 ± 0.025	2.941GlyPhe: 2.941 ± 0.024	5.874GlyGly: 5.874 ± 0.049	1.828GlyHis: 1.828 ± 0.018	3.72GlyIle: 3.72 ± 0.025	3.255GlyLys: 3.255 ± 0.023	6.259GlyLeu: 6.259 ± 0.033	1.559GlyMet: 1.559 ± 0.015	2.722GlyAsn: 2.722 ± 0.021	3.38GlyPro: 3.38 ± 0.03	2.686GlyGln: 2.686 ± 0.023	3.964GlyArg: 3.964 ± 0.025	5.863GlySer: 5.863 ± 0.036	4.266GlyThr: 4.266 ± 0.029	4.388GlyVal: 4.388 ± 0.031	1.243GlyTrp: 1.243 ± 0.012	2.226GlyTyr: 2.226 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	1.836HisAla: 1.836 ± 0.017	0.347HisCys: 0.347 ± 0.007	1.491HisAsp: 1.491 ± 0.017	1.398HisGlu: 1.398 ± 0.014	0.928HisPhe: 0.928 ± 0.012	1.889HisGly: 1.889 ± 0.017	0.885HisHis: 0.885 ± 0.014	1.201HisIle: 1.201 ± 0.013	0.924HisLys: 0.924 ± 0.012	2.213HisLeu: 2.213 ± 0.018	0.525HisMet: 0.525 ± 0.008	0.856HisAsn: 0.856 ± 0.012	1.473HisPro: 1.473 ± 0.015	1.007HisGln: 1.007 ± 0.013	1.457HisArg: 1.457 ± 0.015	1.716HisSer: 1.716 ± 0.018	1.219HisThr: 1.219 ± 0.014	1.509HisVal: 1.509 ± 0.014	0.386HisTrp: 0.386 ± 0.007	0.726HisTyr: 0.726 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.424IleAla: 4.424 ± 0.027	0.791IleCys: 0.791 ± 0.011	3.036IleAsp: 3.036 ± 0.019	2.929IleGlu: 2.929 ± 0.022	2.044IlePhe: 2.044 ± 0.019	3.387IleGly: 3.387 ± 0.028	1.211IleHis: 1.211 ± 0.013	2.703IleIle: 2.703 ± 0.02	2.203IleLys: 2.203 ± 0.018	4.592IleLeu: 4.592 ± 0.029	1.129IleMet: 1.129 ± 0.013	1.888IleAsn: 1.888 ± 0.016	2.963IlePro: 2.963 ± 0.021	1.926IleGln: 1.926 ± 0.016	2.723IleArg: 2.723 ± 0.022	3.926IleSer: 3.926 ± 0.023	3.023IleThr: 3.023 ± 0.024	3.328IleVal: 3.328 ± 0.023	0.827IleTrp: 0.827 ± 0.011	1.452IleTyr: 1.452 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.104LysAla: 4.104 ± 0.03	0.477LysCys: 0.477 ± 0.009	2.746LysAsp: 2.746 ± 0.019	2.984LysGlu: 2.984 ± 0.026	1.461LysPhe: 1.461 ± 0.015	2.767LysGly: 2.767 ± 0.021	1.109LysHis: 1.109 ± 0.013	2.234LysIle: 2.234 ± 0.019	2.979LysLys: 2.979 ± 0.038	3.948LysLeu: 3.948 ± 0.028	0.971LysMet: 0.971 ± 0.01	1.686LysAsn: 1.686 ± 0.016	2.513LysPro: 2.513 ± 0.024	1.81LysGln: 1.81 ± 0.018	3.046LysArg: 3.046 ± 0.025	3.476LysSer: 3.476 ± 0.028	2.868LysThr: 2.868 ± 0.02	2.699LysVal: 2.699 ± 0.023	0.697LysTrp: 0.697 ± 0.01	1.358LysTyr: 1.358 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	8.085LeuAla: 8.085 ± 0.039	1.242LeuCys: 1.242 ± 0.014	5.365LeuAsp: 5.365 ± 0.029	5.499LeuGlu: 5.499 ± 0.038	3.342LeuPhe: 3.342 ± 0.021	6.219LeuGly: 6.219 ± 0.03	2.201LeuHis: 2.201 ± 0.019	3.987LeuIle: 3.987 ± 0.024	3.987LeuLys: 3.987 ± 0.027	8.358LeuLeu: 8.358 ± 0.053	1.859LeuMet: 1.859 ± 0.015	3.135LeuAsn: 3.135 ± 0.024	5.268LeuPro: 5.268 ± 0.031	3.858LeuGln: 3.858 ± 0.026	5.438LeuArg: 5.438 ± 0.034	7.192LeuSer: 7.192 ± 0.034	4.73LeuThr: 4.73 ± 0.028	5.614LeuVal: 5.614 ± 0.034	1.348LeuTrp: 1.348 ± 0.016	2.418LeuTyr: 2.418 ± 0.018	0.0LeuXaa: 0.0 ± 0.0
Met	2.365MetAla: 2.365 ± 0.018	0.251MetCys: 0.251 ± 0.006	1.289MetAsp: 1.289 ± 0.015	1.232MetGlu: 1.232 ± 0.012	0.789MetPhe: 0.789 ± 0.01	1.462MetGly: 1.462 ± 0.017	0.5MetHis: 0.5 ± 0.008	1.077MetIle: 1.077 ± 0.013	0.983MetLys: 0.983 ± 0.012	1.864MetLeu: 1.864 ± 0.016	0.602MetMet: 0.602 ± 0.009	0.815MetAsn: 0.815 ± 0.009	1.276MetPro: 1.276 ± 0.016	0.841MetGln: 0.841 ± 0.013	1.244MetArg: 1.244 ± 0.012	1.916MetSer: 1.916 ± 0.013	1.405MetThr: 1.405 ± 0.015	1.341MetVal: 1.341 ± 0.013	0.286MetTrp: 0.286 ± 0.006	0.547MetTyr: 0.547 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.24AsnAla: 3.24 ± 0.019	0.473AsnCys: 0.473 ± 0.009	2.098AsnAsp: 2.098 ± 0.019	2.03AsnGlu: 2.03 ± 0.019	1.433AsnPhe: 1.433 ± 0.017	3.178AsnGly: 3.178 ± 0.022	0.89AsnHis: 0.89 ± 0.01	2.103AsnIle: 2.103 ± 0.016	1.495AsnLys: 1.495 ± 0.014	3.283AsnLeu: 3.283 ± 0.024	0.895AsnMet: 0.895 ± 0.012	1.577AsnAsn: 1.577 ± 0.016	2.256AsnPro: 2.256 ± 0.019	1.386AsnGln: 1.386 ± 0.015	1.817AsnArg: 1.817 ± 0.016	2.787AsnSer: 2.787 ± 0.021	2.277AsnThr: 2.277 ± 0.019	2.463AsnVal: 2.463 ± 0.019	0.611AsnTrp: 0.611 ± 0.011	1.107AsnTyr: 1.107 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.936ProAla: 4.936 ± 0.03	0.48ProCys: 0.48 ± 0.008	3.195ProAsp: 3.195 ± 0.021	3.688ProGlu: 3.688 ± 0.026	1.97ProPhe: 1.97 ± 0.015	3.908ProGly: 3.908 ± 0.026	1.205ProHis: 1.205 ± 0.014	2.508ProIle: 2.508 ± 0.02	2.436ProLys: 2.436 ± 0.02	4.615ProLeu: 4.615 ± 0.031	1.07ProMet: 1.07 ± 0.013	2.111ProAsn: 2.111 ± 0.019	4.209ProPro: 4.209 ± 0.055	2.323ProGln: 2.323 ± 0.022	3.136ProArg: 3.136 ± 0.026	5.282ProSer: 5.282 ± 0.036	3.694ProThr: 3.694 ± 0.032	3.382ProVal: 3.382 ± 0.02	0.808ProTrp: 0.808 ± 0.011	1.51ProTyr: 1.51 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	3.52GlnAla: 3.52 ± 0.027	0.479GlnCys: 0.479 ± 0.009	2.288GlnAsp: 2.288 ± 0.02	2.385GlnGlu: 2.385 ± 0.02	1.323GlnPhe: 1.323 ± 0.014	2.462GlnGly: 2.462 ± 0.02	1.085GlnHis: 1.085 ± 0.013	1.951GlnIle: 1.951 ± 0.016	1.926GlnLys: 1.926 ± 0.016	3.461GlnLeu: 3.461 ± 0.021	0.904GlnMet: 0.904 ± 0.012	1.585GlnAsn: 1.585 ± 0.017	2.361GlnPro: 2.361 ± 0.023	2.428GlnGln: 2.428 ± 0.034	2.52GlnArg: 2.52 ± 0.021	3.192GlnSer: 3.192 ± 0.023	2.366GlnThr: 2.366 ± 0.021	2.335GlnVal: 2.335 ± 0.019	0.653GlnTrp: 0.653 ± 0.008	1.221GlnTyr: 1.221 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.447ArgAla: 4.447 ± 0.029	0.677ArgCys: 0.677 ± 0.011	3.413ArgAsp: 3.413 ± 0.029	3.402ArgGlu: 3.402 ± 0.028	2.063ArgPhe: 2.063 ± 0.016	3.56ArgGly: 3.56 ± 0.023	1.543ArgHis: 1.543 ± 0.014	2.822ArgIle: 2.822 ± 0.021	3.06ArgLys: 3.06 ± 0.024	5.294ArgLeu: 5.294 ± 0.029	1.227ArgMet: 1.227 ± 0.012	2.21ArgAsn: 2.21 ± 0.019	3.191ArgPro: 3.191 ± 0.027	2.542ArgGln: 2.542 ± 0.022	4.554ArgArg: 4.554 ± 0.039	4.403ArgSer: 4.403 ± 0.034	3.073ArgThr: 3.073 ± 0.024	3.204ArgVal: 3.204 ± 0.022	0.948ArgTrp: 0.948 ± 0.012	1.654ArgTyr: 1.654 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	6.754SerAla: 6.754 ± 0.033	0.929SerCys: 0.929 ± 0.014	4.382SerAsp: 4.382 ± 0.026	4.044SerGlu: 4.044 ± 0.023	3.044SerPhe: 3.044 ± 0.023	5.736SerGly: 5.736 ± 0.038	1.949SerHis: 1.949 ± 0.016	4.147SerIle: 4.147 ± 0.026	3.544SerLys: 3.544 ± 0.027	7.077SerLeu: 7.077 ± 0.033	1.739SerMet: 1.739 ± 0.015	3.071SerAsn: 3.071 ± 0.023	4.882SerPro: 4.882 ± 0.034	3.271SerGln: 3.271 ± 0.023	4.728SerArg: 4.728 ± 0.029	8.716SerSer: 8.716 ± 0.081	5.636SerThr: 5.636 ± 0.046	4.586SerVal: 4.586 ± 0.028	1.275SerTrp: 1.275 ± 0.013	2.193SerTyr: 2.193 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	5.568ThrAla: 5.568 ± 0.032	0.809ThrCys: 0.809 ± 0.013	3.087ThrAsp: 3.087 ± 0.025	3.161ThrGlu: 3.161 ± 0.024	2.34ThrPhe: 2.34 ± 0.021	4.323ThrGly: 4.323 ± 0.029	1.222ThrHis: 1.222 ± 0.013	3.299ThrIle: 3.299 ± 0.026	2.545ThrLys: 2.545 ± 0.021	5.207ThrLeu: 5.207 ± 0.028	1.261ThrMet: 1.261 ± 0.014	2.248ThrAsn: 2.248 ± 0.02	3.926ThrPro: 3.926 ± 0.028	2.132ThrGln: 2.132 ± 0.015	3.015ThrArg: 3.015 ± 0.021	5.502ThrSer: 5.502 ± 0.041	4.722ThrThr: 4.722 ± 0.044	3.876ThrVal: 3.876 ± 0.029	1.003ThrTrp: 1.003 ± 0.013	1.734ThrTyr: 1.734 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.647ValAla: 5.647 ± 0.028	0.823ValCys: 0.823 ± 0.012	3.791ValAsp: 3.791 ± 0.026	3.736ValGlu: 3.736 ± 0.028	2.538ValPhe: 2.538 ± 0.02	4.054ValGly: 4.054 ± 0.026	1.401ValHis: 1.401 ± 0.013	3.067ValIle: 3.067 ± 0.026	2.774ValLys: 2.774 ± 0.018	5.702ValLeu: 5.702 ± 0.034	1.341ValMet: 1.341 ± 0.013	2.269ValAsn: 2.269 ± 0.019	3.53ValPro: 3.53 ± 0.024	2.483ValGln: 2.483 ± 0.019	3.266ValArg: 3.266 ± 0.022	4.61ValSer: 4.61 ± 0.028	3.674ValThr: 3.674 ± 0.031	4.397ValVal: 4.397 ± 0.028	0.927ValTrp: 0.927 ± 0.012	1.828ValTyr: 1.828 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	1.27TrpAla: 1.27 ± 0.013	0.211TrpCys: 0.211 ± 0.005	0.985TrpAsp: 0.985 ± 0.014	0.856TrpGlu: 0.856 ± 0.01	0.621TrpPhe: 0.621 ± 0.01	1.017TrpGly: 1.017 ± 0.013	0.399TrpHis: 0.399 ± 0.007	0.861TrpIle: 0.861 ± 0.011	0.815TrpLys: 0.815 ± 0.01	1.509TrpLeu: 1.509 ± 0.013	0.38TrpMet: 0.38 ± 0.007	0.71TrpAsn: 0.71 ± 0.01	0.705TrpPro: 0.705 ± 0.01	0.66TrpGln: 0.66 ± 0.01	0.999TrpArg: 0.999 ± 0.011	1.195TrpSer: 1.195 ± 0.015	1.045TrpThr: 1.045 ± 0.014	0.953TrpVal: 0.953 ± 0.011	0.312TrpTrp: 0.312 ± 0.007	0.504TrpTyr: 0.504 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.276TyrAla: 2.276 ± 0.017	0.46TyrCys: 0.46 ± 0.007	1.769TyrAsp: 1.769 ± 0.019	1.581TyrGlu: 1.581 ± 0.015	1.235TyrPhe: 1.235 ± 0.012	2.262TyrGly: 2.262 ± 0.023	0.775TyrHis: 0.775 ± 0.01	1.423TyrIle: 1.423 ± 0.015	1.096TyrLys: 1.096 ± 0.012	2.707TyrLeu: 2.707 ± 0.021	0.668TyrMet: 0.668 ± 0.01	1.202TyrAsn: 1.202 ± 0.014	1.488TyrPro: 1.488 ± 0.017	1.158TyrGln: 1.158 ± 0.014	1.549TyrArg: 1.549 ± 0.016	2.127TyrSer: 2.127 ± 0.018	1.741TyrThr: 1.741 ± 0.019	1.684TyrVal: 1.684 ± 0.016	0.519TyrTrp: 0.519 ± 0.01	1.03TyrTyr: 1.03 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 15412 proteins (7589864 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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