Amino acid dipepetide frequency for Asparagus virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.975AlaAla: 6.975 ± 1.784
1.308AlaCys: 1.308 ± 0.986
3.923AlaAsp: 3.923 ± 1.038
3.487AlaGlu: 3.487 ± 0.84
0.872AlaPhe: 0.872 ± 0.468
4.359AlaGly: 4.359 ± 1.801
3.051AlaHis: 3.051 ± 0.99
4.795AlaIle: 4.795 ± 2.335
3.051AlaLys: 3.051 ± 1.134
7.847AlaLeu: 7.847 ± 0.665
1.744AlaMet: 1.744 ± 0.578
3.487AlaAsn: 3.487 ± 0.941
6.539AlaPro: 6.539 ± 2.664
1.308AlaGln: 1.308 ± 0.986
5.231AlaArg: 5.231 ± 1.644
6.539AlaSer: 6.539 ± 2.074
7.411AlaThr: 7.411 ± 1.964
3.923AlaVal: 3.923 ± 2.476
0.436AlaTrp: 0.436 ± 0.234
6.103AlaTyr: 6.103 ± 1.167
0.0AlaXaa: 0.0 ± 0.0
Cys
1.744CysAla: 1.744 ± 2.599
0.436CysCys: 0.436 ± 0.679
0.436CysAsp: 0.436 ± 0.679
0.872CysGlu: 0.872 ± 0.468
0.0CysPhe: 0.0 ± 0.0
1.308CysGly: 1.308 ± 0.986
0.436CysHis: 0.436 ± 1.168
0.0CysIle: 0.0 ± 0.0
1.308CysLys: 1.308 ± 0.581
2.616CysLeu: 2.616 ± 0.931
0.436CysMet: 0.436 ± 0.82
0.872CysAsn: 0.872 ± 0.468
2.18CysPro: 2.18 ± 1.015
1.308CysGln: 1.308 ± 1.118
1.308CysArg: 1.308 ± 0.494
2.18CysSer: 2.18 ± 1.698
0.436CysThr: 0.436 ± 0.234
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.308CysTyr: 1.308 ± 0.494
0.0CysXaa: 0.0 ± 0.0
Asp
2.18AspAla: 2.18 ± 1.015
0.872AspCys: 0.872 ± 0.671
2.18AspAsp: 2.18 ± 1.17
3.051AspGlu: 3.051 ± 0.615
3.051AspPhe: 3.051 ± 0.99
3.487AspGly: 3.487 ± 1.155
0.872AspHis: 0.872 ± 0.468
3.051AspIle: 3.051 ± 1.638
0.0AspLys: 0.0 ± 0.0
6.103AspLeu: 6.103 ± 2.562
1.744AspMet: 1.744 ± 0.936
0.872AspAsn: 0.872 ± 1.055
7.411AspPro: 7.411 ± 3.345
1.308AspGln: 1.308 ± 0.702
2.18AspArg: 2.18 ± 1.01
5.667AspSer: 5.667 ± 0.65
3.923AspThr: 3.923 ± 2.106
2.18AspVal: 2.18 ± 0.663
1.744AspTrp: 1.744 ± 0.936
2.18AspTyr: 2.18 ± 1.17
0.0AspXaa: 0.0 ± 0.0
Glu
6.103GluAla: 6.103 ± 1.167
0.872GluCys: 0.872 ± 0.468
2.616GluAsp: 2.616 ± 0.81
4.359GluGlu: 4.359 ± 1.714
2.616GluPhe: 2.616 ± 1.404
2.616GluGly: 2.616 ± 0.81
0.0GluHis: 0.0 ± 0.0
4.359GluIle: 4.359 ± 2.255
1.744GluLys: 1.744 ± 0.936
4.359GluLeu: 4.359 ± 2.255
0.0GluMet: 0.0 ± 0.0
1.308GluAsn: 1.308 ± 0.702
5.231GluPro: 5.231 ± 1.482
0.0GluGln: 0.0 ± 0.0
3.923GluArg: 3.923 ± 2.106
3.051GluSer: 3.051 ± 1.228
1.744GluThr: 1.744 ± 0.548
3.051GluVal: 3.051 ± 1.134
0.0GluTrp: 0.0 ± 0.0
0.872GluTyr: 0.872 ± 0.546
0.0GluXaa: 0.0 ± 0.0
Phe
3.487PheAla: 3.487 ± 1.155
3.051PheCys: 3.051 ± 0.615
3.051PheAsp: 3.051 ± 0.615
3.487PheGlu: 3.487 ± 1.19
2.18PhePhe: 2.18 ± 1.027
1.308PheGly: 1.308 ± 0.494
1.308PheHis: 1.308 ± 0.702
2.18PheIle: 2.18 ± 1.17
1.308PheLys: 1.308 ± 1.27
3.923PheLeu: 3.923 ± 1.692
1.308PheMet: 1.308 ± 0.702
1.308PheAsn: 1.308 ± 0.702
2.616PhePro: 2.616 ± 0.776
1.744PheGln: 1.744 ± 0.548
2.616PheArg: 2.616 ± 1.1
3.487PheSer: 3.487 ± 1.025
3.051PheThr: 3.051 ± 1.279
1.308PheVal: 1.308 ± 0.581
0.0PheTrp: 0.0 ± 0.0
0.872PheTyr: 0.872 ± 0.671
0.0PheXaa: 0.0 ± 0.0
Gly
4.359GlyAla: 4.359 ± 0.964
1.744GlyCys: 1.744 ± 0.961
4.359GlyAsp: 4.359 ± 0.994
0.872GlyGlu: 0.872 ± 0.925
1.744GlyPhe: 1.744 ± 0.845
3.051GlyGly: 3.051 ± 0.941
1.308GlyHis: 1.308 ± 0.986
1.744GlyIle: 1.744 ± 0.936
2.616GlyLys: 2.616 ± 0.861
3.487GlyLeu: 3.487 ± 2.287
0.0GlyMet: 0.0 ± 0.0
2.616GlyAsn: 2.616 ± 0.829
3.923GlyPro: 3.923 ± 0.838
1.308GlyGln: 1.308 ± 0.702
2.18GlyArg: 2.18 ± 0.702
2.616GlySer: 2.616 ± 1.412
3.923GlyThr: 3.923 ± 1.217
3.487GlyVal: 3.487 ± 2.591
0.872GlyTrp: 0.872 ± 0.671
0.872GlyTyr: 0.872 ± 0.468
0.0GlyXaa: 0.0 ± 0.0
His
0.872HisAla: 0.872 ± 0.468
1.308HisCys: 1.308 ± 1.27
0.872HisAsp: 0.872 ± 0.468
0.872HisGlu: 0.872 ± 0.468
2.616HisPhe: 2.616 ± 0.989
3.923HisGly: 3.923 ± 2.344
2.616HisHis: 2.616 ± 1.1
2.18HisIle: 2.18 ± 0.841
0.872HisLys: 0.872 ± 0.468
4.795HisLeu: 4.795 ± 1.821
0.436HisMet: 0.436 ± 0.234
0.436HisAsn: 0.436 ± 0.234
2.18HisPro: 2.18 ± 1.01
1.744HisGln: 1.744 ± 0.936
3.487HisArg: 3.487 ± 1.096
3.923HisSer: 3.923 ± 1.4
3.051HisThr: 3.051 ± 1.279
0.436HisVal: 0.436 ± 0.234
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.616IleAla: 2.616 ± 1.404
0.436IleCys: 0.436 ± 0.234
3.923IleAsp: 3.923 ± 0.838
2.616IleGlu: 2.616 ± 0.617
3.051IlePhe: 3.051 ± 1.061
1.308IleGly: 1.308 ± 2.062
3.051IleHis: 3.051 ± 0.915
3.051IleIle: 3.051 ± 1.189
3.487IleLys: 3.487 ± 1.155
4.359IleLeu: 4.359 ± 4.041
0.436IleMet: 0.436 ± 0.234
3.487IleAsn: 3.487 ± 1.19
2.18IlePro: 2.18 ± 0.682
3.051IleGln: 3.051 ± 0.615
2.616IleArg: 2.616 ± 0.617
2.616IleSer: 2.616 ± 0.989
3.923IleThr: 3.923 ± 1.221
3.923IleVal: 3.923 ± 0.972
0.0IleTrp: 0.0 ± 0.0
1.308IleTyr: 1.308 ± 0.986
0.0IleXaa: 0.0 ± 0.0
Lys
4.359LysAla: 4.359 ± 1.617
0.436LysCys: 0.436 ± 0.679
3.487LysAsp: 3.487 ± 1.155
1.744LysGlu: 1.744 ± 0.936
2.18LysPhe: 2.18 ± 1.771
1.308LysGly: 1.308 ± 0.702
2.18LysHis: 2.18 ± 0.663
2.18LysIle: 2.18 ± 1.01
1.744LysLys: 1.744 ± 0.578
6.975LysLeu: 6.975 ± 2.379
1.308LysMet: 1.308 ± 0.702
0.436LysAsn: 0.436 ± 0.234
2.18LysPro: 2.18 ± 1.17
1.744LysGln: 1.744 ± 0.936
2.616LysArg: 2.616 ± 1.1
1.744LysSer: 1.744 ± 0.936
3.487LysThr: 3.487 ± 1.273
3.923LysVal: 3.923 ± 0.955
0.872LysTrp: 0.872 ± 0.468
0.872LysTyr: 0.872 ± 1.641
0.0LysXaa: 0.0 ± 0.0
Leu
8.282LeuAla: 8.282 ± 3.493
1.308LeuCys: 1.308 ± 1.949
4.359LeuAsp: 4.359 ± 1.014
4.359LeuGlu: 4.359 ± 1.714
5.231LeuPhe: 5.231 ± 1.466
6.103LeuGly: 6.103 ± 1.23
3.487LeuHis: 3.487 ± 1.096
2.616LeuIle: 2.616 ± 1.141
7.411LeuLys: 7.411 ± 2.526
10.026LeuLeu: 10.026 ± 3.782
0.872LeuMet: 0.872 ± 0.578
5.231LeuAsn: 5.231 ± 2.521
7.847LeuPro: 7.847 ± 1.404
5.231LeuGln: 5.231 ± 0.827
4.795LeuArg: 4.795 ± 1.142
6.103LeuSer: 6.103 ± 3.753
8.718LeuThr: 8.718 ± 2.126
3.923LeuVal: 3.923 ± 0.972
1.308LeuTrp: 1.308 ± 0.494
3.487LeuTyr: 3.487 ± 1.872
0.0LeuXaa: 0.0 ± 0.0
Met
3.051MetAla: 3.051 ± 0.913
0.0MetCys: 0.0 ± 0.0
0.436MetAsp: 0.436 ± 0.234
0.436MetGlu: 0.436 ± 0.679
0.436MetPhe: 0.436 ± 0.234
0.436MetGly: 0.436 ± 0.234
0.872MetHis: 0.872 ± 0.468
0.436MetIle: 0.436 ± 0.82
1.744MetLys: 1.744 ± 0.936
3.051MetLeu: 3.051 ± 1.638
0.436MetMet: 0.436 ± 0.82
1.308MetAsn: 1.308 ± 0.702
1.308MetPro: 1.308 ± 2.213
1.744MetGln: 1.744 ± 0.936
2.18MetArg: 2.18 ± 1.17
0.872MetSer: 0.872 ± 0.468
0.436MetThr: 0.436 ± 0.234
0.0MetVal: 0.0 ± 0.0
0.436MetTrp: 0.436 ± 0.82
1.744MetTyr: 1.744 ± 1.342
0.0MetXaa: 0.0 ± 0.0
Asn
4.795AsnAla: 4.795 ± 2.575
1.744AsnCys: 1.744 ± 0.548
2.18AsnAsp: 2.18 ± 1.17
0.872AsnGlu: 0.872 ± 0.468
3.051AsnPhe: 3.051 ± 0.615
1.308AsnGly: 1.308 ± 2.427
2.18AsnHis: 2.18 ± 1.003
3.051AsnIle: 3.051 ± 1.625
0.436AsnLys: 0.436 ± 0.234
3.487AsnLeu: 3.487 ± 1.776
1.308AsnMet: 1.308 ± 0.581
0.436AsnAsn: 0.436 ± 0.234
1.744AsnPro: 1.744 ± 0.845
0.436AsnGln: 0.436 ± 0.234
0.872AsnArg: 0.872 ± 0.468
3.051AsnSer: 3.051 ± 2.373
2.18AsnThr: 2.18 ± 0.663
1.744AsnVal: 1.744 ± 0.578
0.0AsnTrp: 0.0 ± 0.0
2.18AsnTyr: 2.18 ± 2.029
0.0AsnXaa: 0.0 ± 0.0
Pro
9.154ProAla: 9.154 ± 1.667
0.872ProCys: 0.872 ± 0.925
4.795ProAsp: 4.795 ± 0.561
6.539ProGlu: 6.539 ± 2.105
2.616ProPhe: 2.616 ± 0.776
1.744ProGly: 1.744 ± 0.971
2.18ProHis: 2.18 ± 2.234
4.795ProIle: 4.795 ± 1.031
3.923ProLys: 3.923 ± 2.106
6.103ProLeu: 6.103 ± 2.035
0.872ProMet: 0.872 ± 0.468
1.744ProAsn: 1.744 ± 1.092
6.539ProPro: 6.539 ± 2.985
0.436ProGln: 0.436 ± 0.679
1.744ProArg: 1.744 ± 0.845
6.103ProSer: 6.103 ± 3.26
6.539ProThr: 6.539 ± 1.387
6.103ProVal: 6.103 ± 0.621
1.308ProTrp: 1.308 ± 0.865
2.18ProTyr: 2.18 ± 0.682
0.0ProXaa: 0.0 ± 0.0
Gln
1.744GlnAla: 1.744 ± 2.298
0.0GlnCys: 0.0 ± 0.0
2.616GlnAsp: 2.616 ± 0.989
1.308GlnGlu: 1.308 ± 0.702
1.744GlnPhe: 1.744 ± 1.342
1.308GlnGly: 1.308 ± 0.702
1.308GlnHis: 1.308 ± 0.702
0.872GlnIle: 0.872 ± 0.468
1.308GlnLys: 1.308 ± 0.702
3.487GlnLeu: 3.487 ± 1.096
1.308GlnMet: 1.308 ± 0.702
1.308GlnAsn: 1.308 ± 1.309
2.616GlnPro: 2.616 ± 0.617
1.744GlnGln: 1.744 ± 0.936
2.18GlnArg: 2.18 ± 1.233
4.795GlnSer: 4.795 ± 0.561
3.051GlnThr: 3.051 ± 1.638
2.616GlnVal: 2.616 ± 1.729
1.308GlnTrp: 1.308 ± 0.986
0.872GlnTyr: 0.872 ± 1.443
0.0GlnXaa: 0.0 ± 0.0
Arg
4.359ArgAla: 4.359 ± 2.024
1.308ArgCys: 1.308 ± 0.986
3.051ArgAsp: 3.051 ± 1.638
1.308ArgGlu: 1.308 ± 0.581
1.308ArgPhe: 1.308 ± 0.494
1.744ArgGly: 1.744 ± 0.845
2.616ArgHis: 2.616 ± 1.638
2.616ArgIle: 2.616 ± 1.168
1.744ArgLys: 1.744 ± 1.092
6.103ArgLeu: 6.103 ± 2.624
0.436ArgMet: 0.436 ± 1.064
3.051ArgAsn: 3.051 ± 1.638
2.18ArgPro: 2.18 ± 1.003
5.667ArgGln: 5.667 ± 3.239
2.616ArgArg: 2.616 ± 0.989
3.487ArgSer: 3.487 ± 0.696
4.795ArgThr: 4.795 ± 1.347
2.616ArgVal: 2.616 ± 2.107
0.0ArgTrp: 0.0 ± 0.0
2.18ArgTyr: 2.18 ± 1.17
0.0ArgXaa: 0.0 ± 0.0
Ser
3.923SerAla: 3.923 ± 0.617
0.872SerCys: 0.872 ± 1.443
4.795SerAsp: 4.795 ± 1.157
4.359SerGlu: 4.359 ± 1.365
3.487SerPhe: 3.487 ± 1.273
3.487SerGly: 3.487 ± 1.012
2.18SerHis: 2.18 ± 0.928
3.487SerIle: 3.487 ± 1.384
3.051SerLys: 3.051 ± 1.228
9.154SerLeu: 9.154 ± 3.996
2.18SerMet: 2.18 ± 0.679
2.616SerAsn: 2.616 ± 2.382
4.359SerPro: 4.359 ± 0.698
1.744SerGln: 1.744 ± 1.093
3.487SerArg: 3.487 ± 1.012
6.103SerSer: 6.103 ± 2.137
7.411SerThr: 7.411 ± 1.828
3.487SerVal: 3.487 ± 2.452
0.436SerTrp: 0.436 ± 0.234
2.18SerTyr: 2.18 ± 0.682
0.0SerXaa: 0.0 ± 0.0
Thr
4.359ThrAla: 4.359 ± 1.091
1.308ThrCys: 1.308 ± 0.494
3.051ThrAsp: 3.051 ± 1.554
2.18ThrGlu: 2.18 ± 1.17
3.487ThrPhe: 3.487 ± 1.273
3.923ThrGly: 3.923 ± 1.426
2.616ThrHis: 2.616 ± 0.861
4.359ThrIle: 4.359 ± 2.341
5.667ThrLys: 5.667 ± 1.07
8.282ThrLeu: 8.282 ± 1.502
2.616ThrMet: 2.616 ± 1.1
2.616ThrAsn: 2.616 ± 2.107
9.59ThrPro: 9.59 ± 2.146
2.18ThrGln: 2.18 ± 1.17
3.487ThrArg: 3.487 ± 3.259
3.051ThrSer: 3.051 ± 0.99
6.103ThrThr: 6.103 ± 3.078
4.795ThrVal: 4.795 ± 1.309
0.436ThrTrp: 0.436 ± 0.234
0.872ThrTyr: 0.872 ± 0.468
0.0ThrXaa: 0.0 ± 0.0
Val
1.744ValAla: 1.744 ± 0.845
0.872ValCys: 0.872 ± 1.443
2.616ValAsp: 2.616 ± 2.045
2.616ValGlu: 2.616 ± 1.404
1.308ValPhe: 1.308 ± 0.986
1.744ValGly: 1.744 ± 0.578
2.616ValHis: 2.616 ± 1.412
3.051ValIle: 3.051 ± 0.913
3.051ValLys: 3.051 ± 0.913
3.923ValLeu: 3.923 ± 1.713
2.18ValMet: 2.18 ± 0.947
1.308ValAsn: 1.308 ± 0.581
3.923ValPro: 3.923 ± 1.091
4.359ValGln: 4.359 ± 1.548
4.795ValArg: 4.795 ± 2.131
3.923ValSer: 3.923 ± 2.235
3.923ValThr: 3.923 ± 1.783
3.487ValVal: 3.487 ± 2.996
0.436ValTrp: 0.436 ± 0.82
2.18ValTyr: 2.18 ± 1.17
0.0ValXaa: 0.0 ± 0.0
Trp
1.308TrpAla: 1.308 ± 0.702
0.0TrpCys: 0.0 ± 0.0
0.436TrpAsp: 0.436 ± 0.82
0.872TrpGlu: 0.872 ± 0.468
0.436TrpPhe: 0.436 ± 0.234
0.436TrpGly: 0.436 ± 0.679
0.436TrpHis: 0.436 ± 0.234
0.0TrpIle: 0.0 ± 0.0
0.436TrpLys: 0.436 ± 0.234
0.436TrpLeu: 0.436 ± 0.234
0.436TrpMet: 0.436 ± 0.234
1.308TrpAsn: 1.308 ± 1.309
0.872TrpPro: 0.872 ± 1.055
0.436TrpGln: 0.436 ± 0.234
0.436TrpArg: 0.436 ± 0.234
0.436TrpSer: 0.436 ± 0.234
0.0TrpThr: 0.0 ± 0.0
1.744TrpVal: 1.744 ± 0.578
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.975TyrAla: 6.975 ± 1.235
0.436TyrCys: 0.436 ± 0.234
0.872TyrAsp: 0.872 ± 0.468
2.616TyrGlu: 2.616 ± 0.931
2.18TyrPhe: 2.18 ± 0.942
2.18TyrGly: 2.18 ± 0.663
1.308TyrHis: 1.308 ± 0.702
2.616TyrIle: 2.616 ± 0.861
0.872TyrLys: 0.872 ± 0.468
2.616TyrLeu: 2.616 ± 0.861
0.872TyrMet: 0.872 ± 0.442
1.308TyrAsn: 1.308 ± 0.494
0.872TyrPro: 0.872 ± 0.468
0.0TyrGln: 0.0 ± 0.0
0.436TyrArg: 0.436 ± 0.234
3.051TyrSer: 3.051 ± 0.915
0.872TyrThr: 0.872 ± 0.468
1.308TyrVal: 1.308 ± 1.964
0.872TyrTrp: 0.872 ± 0.468
0.436TyrTyr: 0.436 ± 0.234
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2295 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski