Amino acid dipepetide frequency for Odonata-associated circular virus 21

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.527AlaAla: 1.527 ± 1.136
3.053AlaCys: 3.053 ± 0.143
6.107AlaAsp: 6.107 ± 1.844
3.053AlaGlu: 3.053 ± 0.143
0.0AlaPhe: 0.0 ± 0.0
10.687AlaGly: 10.687 ± 2.694
1.527AlaHis: 1.527 ± 0.993
4.58AlaIle: 4.58 ± 2.98
4.58AlaLys: 4.58 ± 1.279
6.107AlaLeu: 6.107 ± 0.286
3.053AlaMet: 3.053 ± 0.143
3.053AlaAsn: 3.053 ± 0.143
1.527AlaPro: 1.527 ± 0.993
1.527AlaGln: 1.527 ± 0.993
3.053AlaArg: 3.053 ± 0.143
6.107AlaSer: 6.107 ± 0.286
3.053AlaThr: 3.053 ± 1.987
1.527AlaVal: 1.527 ± 0.993
1.527AlaTrp: 1.527 ± 1.136
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
3.053CysAla: 3.053 ± 0.143
0.0CysCys: 0.0 ± 0.0
1.527CysAsp: 1.527 ± 1.136
3.053CysGlu: 3.053 ± 2.273
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
3.053CysIle: 3.053 ± 2.273
1.527CysLys: 1.527 ± 0.993
1.527CysLeu: 1.527 ± 1.136
3.053CysMet: 3.053 ± 0.143
1.527CysAsn: 1.527 ± 1.136
0.0CysPro: 0.0 ± 0.0
1.527CysGln: 1.527 ± 0.993
3.053CysArg: 3.053 ± 2.273
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.527CysTyr: 1.527 ± 1.136
0.0CysXaa: 0.0 ± 0.0
Asp
1.527AspAla: 1.527 ± 0.993
1.527AspCys: 1.527 ± 1.136
3.053AspAsp: 3.053 ± 1.987
1.527AspGlu: 1.527 ± 1.136
3.053AspPhe: 3.053 ± 0.143
10.687AspGly: 10.687 ± 1.566
0.0AspHis: 0.0 ± 0.0
6.107AspIle: 6.107 ± 1.844
1.527AspLys: 1.527 ± 1.136
3.053AspLeu: 3.053 ± 0.143
1.527AspMet: 1.527 ± 0.993
1.527AspAsn: 1.527 ± 1.136
1.527AspPro: 1.527 ± 0.993
1.527AspGln: 1.527 ± 1.136
4.58AspArg: 4.58 ± 3.409
1.527AspSer: 1.527 ± 1.136
3.053AspThr: 3.053 ± 0.143
3.053AspVal: 3.053 ± 0.143
1.527AspTrp: 1.527 ± 1.136
3.053AspTyr: 3.053 ± 0.143
0.0AspXaa: 0.0 ± 0.0
Glu
3.053GluAla: 3.053 ± 0.143
3.053GluCys: 3.053 ± 2.273
6.107GluAsp: 6.107 ± 2.416
9.16GluGlu: 9.16 ± 6.819
1.527GluPhe: 1.527 ± 0.993
1.527GluGly: 1.527 ± 1.136
1.527GluHis: 1.527 ± 1.136
4.58GluIle: 4.58 ± 0.85
4.58GluLys: 4.58 ± 0.85
4.58GluLeu: 4.58 ± 1.279
3.053GluMet: 3.053 ± 0.143
4.58GluAsn: 4.58 ± 0.85
1.527GluPro: 1.527 ± 1.136
0.0GluGln: 0.0 ± 0.0
6.107GluArg: 6.107 ± 4.546
3.053GluSer: 3.053 ± 1.987
4.58GluThr: 4.58 ± 0.85
4.58GluVal: 4.58 ± 2.98
1.527GluTrp: 1.527 ± 1.136
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.053PheAla: 3.053 ± 1.987
1.527PheCys: 1.527 ± 1.136
0.0PheAsp: 0.0 ± 0.0
4.58PheGlu: 4.58 ± 1.279
0.0PhePhe: 0.0 ± 0.0
3.053PheGly: 3.053 ± 2.273
0.0PheHis: 0.0 ± 0.0
1.527PheIle: 1.527 ± 1.136
0.0PheLys: 0.0 ± 0.0
1.527PheLeu: 1.527 ± 1.136
0.0PheMet: 0.0 ± 0.0
4.58PheAsn: 4.58 ± 2.98
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
3.053PheArg: 3.053 ± 0.143
4.58PheSer: 4.58 ± 0.85
1.527PheThr: 1.527 ± 1.136
1.527PheVal: 1.527 ± 1.136
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
7.634GlyAla: 7.634 ± 2.837
0.0GlyCys: 0.0 ± 0.0
6.107GlyAsp: 6.107 ± 2.416
4.58GlyGlu: 4.58 ± 0.85
4.58GlyPhe: 4.58 ± 0.85
1.527GlyGly: 1.527 ± 0.993
3.053GlyHis: 3.053 ± 0.143
3.053GlyIle: 3.053 ± 2.273
7.634GlyLys: 7.634 ± 5.682
7.634GlyLeu: 7.634 ± 4.967
3.053GlyMet: 3.053 ± 1.987
4.58GlyAsn: 4.58 ± 2.98
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
4.58GlyArg: 4.58 ± 0.85
1.527GlySer: 1.527 ± 0.993
3.053GlyThr: 3.053 ± 2.273
7.634GlyVal: 7.634 ± 0.707
1.527GlyTrp: 1.527 ± 1.136
4.58GlyTyr: 4.58 ± 3.409
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.527HisGlu: 1.527 ± 1.136
1.527HisPhe: 1.527 ± 1.136
1.527HisGly: 1.527 ± 1.136
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.527HisLys: 1.527 ± 1.136
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.527HisAsn: 1.527 ± 1.136
4.58HisPro: 4.58 ± 0.85
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
1.527HisThr: 1.527 ± 0.993
1.527HisVal: 1.527 ± 1.136
0.0HisTrp: 0.0 ± 0.0
3.053HisTyr: 3.053 ± 2.273
0.0HisXaa: 0.0 ± 0.0
Ile
3.053IleAla: 3.053 ± 1.987
1.527IleCys: 1.527 ± 1.136
4.58IleAsp: 4.58 ± 3.409
1.527IleGlu: 1.527 ± 0.993
0.0IlePhe: 0.0 ± 0.0
9.16IleGly: 9.16 ± 2.559
0.0IleHis: 0.0 ± 0.0
10.687IleIle: 10.687 ± 2.694
4.58IleLys: 4.58 ± 1.279
6.107IleLeu: 6.107 ± 0.286
3.053IleMet: 3.053 ± 1.987
1.527IleAsn: 1.527 ± 1.136
4.58IlePro: 4.58 ± 1.279
1.527IleGln: 1.527 ± 0.993
3.053IleArg: 3.053 ± 0.143
6.107IleSer: 6.107 ± 0.286
4.58IleThr: 4.58 ± 1.279
6.107IleVal: 6.107 ± 1.844
1.527IleTrp: 1.527 ± 1.136
1.527IleTyr: 1.527 ± 0.993
0.0IleXaa: 0.0 ± 0.0
Lys
6.107LysAla: 6.107 ± 0.286
3.053LysCys: 3.053 ± 2.273
1.527LysAsp: 1.527 ± 1.136
3.053LysGlu: 3.053 ± 2.273
1.527LysPhe: 1.527 ± 1.136
6.107LysGly: 6.107 ± 2.416
1.527LysHis: 1.527 ± 1.136
3.053LysIle: 3.053 ± 0.143
3.053LysLys: 3.053 ± 0.143
3.053LysLeu: 3.053 ± 0.143
3.053LysMet: 3.053 ± 0.143
0.0LysAsn: 0.0 ± 0.0
1.527LysPro: 1.527 ± 0.993
3.053LysGln: 3.053 ± 0.143
0.0LysArg: 0.0 ± 0.0
4.58LysSer: 4.58 ± 3.409
7.634LysThr: 7.634 ± 0.707
0.0LysVal: 0.0 ± 0.0
1.527LysTrp: 1.527 ± 1.136
6.107LysTyr: 6.107 ± 0.286
0.0LysXaa: 0.0 ± 0.0
Leu
1.527LeuAla: 1.527 ± 0.993
3.053LeuCys: 3.053 ± 0.143
3.053LeuAsp: 3.053 ± 2.273
7.634LeuGlu: 7.634 ± 1.423
0.0LeuPhe: 0.0 ± 0.0
1.527LeuGly: 1.527 ± 1.136
1.527LeuHis: 1.527 ± 0.993
6.107LeuIle: 6.107 ± 0.286
1.527LeuLys: 1.527 ± 1.136
1.527LeuLeu: 1.527 ± 0.993
0.0LeuMet: 0.0 ± 0.0
3.053LeuAsn: 3.053 ± 0.143
3.053LeuPro: 3.053 ± 0.143
3.053LeuGln: 3.053 ± 1.987
1.527LeuArg: 1.527 ± 1.136
4.58LeuSer: 4.58 ± 2.98
1.527LeuThr: 1.527 ± 1.136
4.58LeuVal: 4.58 ± 0.85
0.0LeuTrp: 0.0 ± 0.0
4.58LeuTyr: 4.58 ± 0.85
0.0LeuXaa: 0.0 ± 0.0
Met
4.58MetAla: 4.58 ± 2.98
0.0MetCys: 0.0 ± 0.0
3.053MetAsp: 3.053 ± 0.143
1.527MetGlu: 1.527 ± 0.993
3.053MetPhe: 3.053 ± 0.143
0.0MetGly: 0.0 ± 0.0
1.527MetHis: 1.527 ± 1.136
0.0MetIle: 0.0 ± 0.0
3.053MetLys: 3.053 ± 0.143
1.527MetLeu: 1.527 ± 0.993
0.0MetMet: 0.0 ± 0.741
1.527MetAsn: 1.527 ± 0.993
4.58MetPro: 4.58 ± 2.98
0.0MetGln: 0.0 ± 0.0
1.527MetArg: 1.527 ± 0.993
3.053MetSer: 3.053 ± 0.143
3.053MetThr: 3.053 ± 1.987
4.58MetVal: 4.58 ± 2.98
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.527AsnAla: 1.527 ± 0.993
4.58AsnCys: 4.58 ± 0.85
1.527AsnAsp: 1.527 ± 1.136
1.527AsnGlu: 1.527 ± 1.136
0.0AsnPhe: 0.0 ± 0.0
6.107AsnGly: 6.107 ± 3.973
1.527AsnHis: 1.527 ± 1.136
1.527AsnIle: 1.527 ± 1.136
1.527AsnLys: 1.527 ± 0.993
1.527AsnLeu: 1.527 ± 1.136
3.053AsnMet: 3.053 ± 1.987
0.0AsnAsn: 0.0 ± 0.0
3.053AsnPro: 3.053 ± 0.143
1.527AsnGln: 1.527 ± 0.993
4.58AsnArg: 4.58 ± 0.85
3.053AsnSer: 3.053 ± 1.987
3.053AsnThr: 3.053 ± 1.987
3.053AsnVal: 3.053 ± 0.143
0.0AsnTrp: 0.0 ± 0.0
1.527AsnTyr: 1.527 ± 1.136
0.0AsnXaa: 0.0 ± 0.0
Pro
3.053ProAla: 3.053 ± 0.143
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
1.527ProGlu: 1.527 ± 0.993
0.0ProPhe: 0.0 ± 0.0
1.527ProGly: 1.527 ± 0.993
0.0ProHis: 0.0 ± 0.0
6.107ProIle: 6.107 ± 1.844
0.0ProLys: 0.0 ± 0.0
6.107ProLeu: 6.107 ± 0.286
1.527ProMet: 1.527 ± 0.993
1.527ProAsn: 1.527 ± 0.993
1.527ProPro: 1.527 ± 0.993
3.053ProGln: 3.053 ± 1.987
6.107ProArg: 6.107 ± 2.416
4.58ProSer: 4.58 ± 2.98
3.053ProThr: 3.053 ± 0.143
1.527ProVal: 1.527 ± 0.993
0.0ProTrp: 0.0 ± 0.0
1.527ProTyr: 1.527 ± 0.993
0.0ProXaa: 0.0 ± 0.0
Gln
3.053GlnAla: 3.053 ± 1.987
0.0GlnCys: 0.0 ± 0.0
3.053GlnAsp: 3.053 ± 1.987
3.053GlnGlu: 3.053 ± 1.987
1.527GlnPhe: 1.527 ± 1.136
1.527GlnGly: 1.527 ± 1.136
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.527GlnLys: 1.527 ± 1.136
1.527GlnLeu: 1.527 ± 0.993
1.527GlnMet: 1.527 ± 0.993
4.58GlnAsn: 4.58 ± 0.85
1.527GlnPro: 1.527 ± 0.993
0.0GlnGln: 0.0 ± 0.0
0.0GlnArg: 0.0 ± 0.0
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
3.053GlnVal: 3.053 ± 1.987
0.0GlnTrp: 0.0 ± 0.0
1.527GlnTyr: 1.527 ± 1.136
0.0GlnXaa: 0.0 ± 0.0
Arg
4.58ArgAla: 4.58 ± 1.279
1.527ArgCys: 1.527 ± 1.136
3.053ArgAsp: 3.053 ± 0.143
6.107ArgGlu: 6.107 ± 0.286
1.527ArgPhe: 1.527 ± 0.993
3.053ArgGly: 3.053 ± 0.143
1.527ArgHis: 1.527 ± 1.136
3.053ArgIle: 3.053 ± 1.987
1.527ArgLys: 1.527 ± 1.136
1.527ArgLeu: 1.527 ± 1.136
3.053ArgMet: 3.053 ± 0.696
0.0ArgAsn: 0.0 ± 0.0
4.58ArgPro: 4.58 ± 1.279
1.527ArgGln: 1.527 ± 0.993
3.053ArgArg: 3.053 ± 2.273
4.58ArgSer: 4.58 ± 1.279
6.107ArgThr: 6.107 ± 0.286
1.527ArgVal: 1.527 ± 1.136
1.527ArgTrp: 1.527 ± 1.136
4.58ArgTyr: 4.58 ± 3.409
0.0ArgXaa: 0.0 ± 0.0
Ser
4.58SerAla: 4.58 ± 1.279
0.0SerCys: 0.0 ± 0.0
3.053SerAsp: 3.053 ± 1.987
3.053SerGlu: 3.053 ± 1.987
3.053SerPhe: 3.053 ± 0.143
3.053SerGly: 3.053 ± 1.987
1.527SerHis: 1.527 ± 1.136
3.053SerIle: 3.053 ± 0.143
6.107SerLys: 6.107 ± 0.286
4.58SerLeu: 4.58 ± 0.85
4.58SerMet: 4.58 ± 2.98
1.527SerAsn: 1.527 ± 0.993
1.527SerPro: 1.527 ± 0.993
3.053SerGln: 3.053 ± 1.987
3.053SerArg: 3.053 ± 0.143
6.107SerSer: 6.107 ± 3.973
7.634SerThr: 7.634 ± 2.837
4.58SerVal: 4.58 ± 0.85
1.527SerTrp: 1.527 ± 1.136
1.527SerTyr: 1.527 ± 1.136
0.0SerXaa: 0.0 ± 0.0
Thr
4.58ThrAla: 4.58 ± 0.85
0.0ThrCys: 0.0 ± 0.0
1.527ThrAsp: 1.527 ± 0.993
6.107ThrGlu: 6.107 ± 2.416
1.527ThrPhe: 1.527 ± 1.136
7.634ThrGly: 7.634 ± 0.707
0.0ThrHis: 0.0 ± 0.0
4.58ThrIle: 4.58 ± 1.279
4.58ThrLys: 4.58 ± 0.85
0.0ThrLeu: 0.0 ± 0.0
3.053ThrMet: 3.053 ± 1.987
4.58ThrAsn: 4.58 ± 0.85
3.053ThrPro: 3.053 ± 1.987
1.527ThrGln: 1.527 ± 0.993
1.527ThrArg: 1.527 ± 1.136
3.053ThrSer: 3.053 ± 0.143
3.053ThrThr: 3.053 ± 0.143
3.053ThrVal: 3.053 ± 0.143
1.527ThrTrp: 1.527 ± 0.993
9.16ThrTyr: 9.16 ± 3.83
0.0ThrXaa: 0.0 ± 0.0
Val
3.053ValAla: 3.053 ± 0.143
0.0ValCys: 0.0 ± 0.0
4.58ValAsp: 4.58 ± 1.279
4.58ValGlu: 4.58 ± 0.85
6.107ValPhe: 6.107 ± 0.286
4.58ValGly: 4.58 ± 2.98
0.0ValHis: 0.0 ± 0.0
3.053ValIle: 3.053 ± 0.143
7.634ValLys: 7.634 ± 3.552
0.0ValLeu: 0.0 ± 0.0
0.0ValMet: 0.0 ± 0.0
1.527ValAsn: 1.527 ± 0.993
1.527ValPro: 1.527 ± 0.993
1.527ValGln: 1.527 ± 1.136
4.58ValArg: 4.58 ± 2.98
7.634ValSer: 7.634 ± 4.967
3.053ValThr: 3.053 ± 1.987
3.053ValVal: 3.053 ± 0.143
1.527ValTrp: 1.527 ± 1.136
3.053ValTyr: 3.053 ± 1.987
0.0ValXaa: 0.0 ± 0.0
Trp
1.527TrpAla: 1.527 ± 1.136
0.0TrpCys: 0.0 ± 0.0
1.527TrpAsp: 1.527 ± 1.136
1.527TrpGlu: 1.527 ± 1.136
1.527TrpPhe: 1.527 ± 1.136
0.0TrpGly: 0.0 ± 0.0
1.527TrpHis: 1.527 ± 1.136
1.527TrpIle: 1.527 ± 1.136
0.0TrpLys: 0.0 ± 0.0
1.527TrpLeu: 1.527 ± 1.136
0.0TrpMet: 0.0 ± 0.0
1.527TrpAsn: 1.527 ± 1.136
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.527TrpArg: 1.527 ± 1.136
1.527TrpSer: 1.527 ± 0.993
0.0TrpThr: 0.0 ± 0.0
1.527TrpVal: 1.527 ± 1.136
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.58TyrAla: 4.58 ± 1.279
1.527TyrCys: 1.527 ± 1.136
1.527TyrAsp: 1.527 ± 0.993
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
3.053TyrGly: 3.053 ± 0.143
1.527TyrHis: 1.527 ± 1.136
9.16TyrIle: 9.16 ± 4.689
3.053TyrLys: 3.053 ± 0.143
0.0TyrLeu: 0.0 ± 0.0
0.0TyrMet: 0.0 ± 0.0
1.527TyrAsn: 1.527 ± 0.993
3.053TyrPro: 3.053 ± 1.987
3.053TyrGln: 3.053 ± 2.273
3.053TyrArg: 3.053 ± 0.143
1.527TyrSer: 1.527 ± 0.993
4.58TyrThr: 4.58 ± 0.85
4.58TyrVal: 4.58 ± 0.85
1.527TyrTrp: 1.527 ± 1.136
7.634TyrTyr: 7.634 ± 2.837
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (656 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski