Amino acid dipepetide frequency for Odoribacter splanchnicus (strain ATCC 29572 / DSM 20712 / CIP 104287 / JCM 15291 / NCTC 10825 / 1651/6) (Bacteroides splanchnicus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.36AlaAla: 5.36 ± 0.089
1.029AlaCys: 1.029 ± 0.033
4.152AlaAsp: 4.152 ± 0.068
4.775AlaGlu: 4.775 ± 0.072
3.041AlaPhe: 3.041 ± 0.053
5.565AlaGly: 5.565 ± 0.079
1.141AlaHis: 1.141 ± 0.032
4.624AlaIle: 4.624 ± 0.073
3.714AlaLys: 3.714 ± 0.058
6.648AlaLeu: 6.648 ± 0.078
1.706AlaMet: 1.706 ± 0.041
2.793AlaAsn: 2.793 ± 0.052
2.108AlaPro: 2.108 ± 0.036
2.344AlaGln: 2.344 ± 0.044
3.29AlaArg: 3.29 ± 0.053
3.857AlaSer: 3.857 ± 0.062
3.636AlaThr: 3.636 ± 0.058
4.771AlaVal: 4.771 ± 0.073
0.851AlaTrp: 0.851 ± 0.025
2.932AlaTyr: 2.932 ± 0.048
0.0AlaXaa: 0.0 ± 0.0
Cys
0.676CysAla: 0.676 ± 0.025
0.219CysCys: 0.219 ± 0.014
0.612CysAsp: 0.612 ± 0.024
0.673CysGlu: 0.673 ± 0.022
0.678CysPhe: 0.678 ± 0.024
1.036CysGly: 1.036 ± 0.035
0.292CysHis: 0.292 ± 0.014
0.916CysIle: 0.916 ± 0.03
0.663CysLys: 0.663 ± 0.025
1.21CysLeu: 1.21 ± 0.033
0.307CysMet: 0.307 ± 0.016
0.544CysAsn: 0.544 ± 0.022
0.533CysPro: 0.533 ± 0.023
0.377CysGln: 0.377 ± 0.019
0.795CysArg: 0.795 ± 0.028
0.781CysSer: 0.781 ± 0.027
0.628CysThr: 0.628 ± 0.025
0.747CysVal: 0.747 ± 0.025
0.158CysTrp: 0.158 ± 0.012
0.496CysTyr: 0.496 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
3.317AspAla: 3.317 ± 0.051
0.606AspCys: 0.606 ± 0.022
2.444AspAsp: 2.444 ± 0.056
3.781AspGlu: 3.781 ± 0.053
3.094AspPhe: 3.094 ± 0.052
3.637AspGly: 3.637 ± 0.059
0.861AspHis: 0.861 ± 0.023
4.187AspIle: 4.187 ± 0.072
3.815AspLys: 3.815 ± 0.062
4.924AspLeu: 4.924 ± 0.064
1.462AspMet: 1.462 ± 0.036
2.463AspAsn: 2.463 ± 0.045
2.165AspPro: 2.165 ± 0.045
1.485AspGln: 1.485 ± 0.039
2.871AspArg: 2.871 ± 0.048
3.08AspSer: 3.08 ± 0.055
2.686AspThr: 2.686 ± 0.049
3.24AspVal: 3.24 ± 0.052
0.817AspTrp: 0.817 ± 0.026
2.986AspTyr: 2.986 ± 0.059
0.0AspXaa: 0.0 ± 0.0
Glu
4.866GluAla: 4.866 ± 0.063
0.637GluCys: 0.637 ± 0.026
3.361GluAsp: 3.361 ± 0.055
5.523GluGlu: 5.523 ± 0.096
2.659GluPhe: 2.659 ± 0.053
4.262GluGly: 4.262 ± 0.056
1.245GluHis: 1.245 ± 0.029
5.143GluIle: 5.143 ± 0.064
5.76GluLys: 5.76 ± 0.079
6.399GluLeu: 6.399 ± 0.081
2.024GluMet: 2.024 ± 0.041
3.821GluAsn: 3.821 ± 0.051
1.672GluPro: 1.672 ± 0.037
2.803GluGln: 2.803 ± 0.054
3.324GluArg: 3.324 ± 0.06
3.004GluSer: 3.004 ± 0.048
3.295GluThr: 3.295 ± 0.063
4.868GluVal: 4.868 ± 0.071
0.878GluTrp: 0.878 ± 0.025
2.877GluTyr: 2.877 ± 0.055
0.0GluXaa: 0.0 ± 0.0
Phe
2.946PheAla: 2.946 ± 0.055
0.711PheCys: 0.711 ± 0.025
2.8PheAsp: 2.8 ± 0.045
2.69PheGlu: 2.69 ± 0.046
2.31PhePhe: 2.31 ± 0.051
3.272PheGly: 3.272 ± 0.056
0.821PheHis: 0.821 ± 0.026
3.518PheIle: 3.518 ± 0.058
2.423PheLys: 2.423 ± 0.04
4.277PheLeu: 4.277 ± 0.077
1.23PheMet: 1.23 ± 0.035
2.311PheAsn: 2.311 ± 0.048
1.802PhePro: 1.802 ± 0.04
1.453PheGln: 1.453 ± 0.033
2.531PheArg: 2.531 ± 0.049
3.514PheSer: 3.514 ± 0.063
2.806PheThr: 2.806 ± 0.05
2.891PheVal: 2.891 ± 0.049
0.582PheTrp: 0.582 ± 0.019
2.105PheTyr: 2.105 ± 0.04
0.0PheXaa: 0.0 ± 0.0
Gly
4.123GlyAla: 4.123 ± 0.071
0.952GlyCys: 0.952 ± 0.031
3.358GlyAsp: 3.358 ± 0.059
4.651GlyGlu: 4.651 ± 0.068
3.229GlyPhe: 3.229 ± 0.052
4.81GlyGly: 4.81 ± 0.077
1.28GlyHis: 1.28 ± 0.039
5.635GlyIle: 5.635 ± 0.084
5.509GlyLys: 5.509 ± 0.068
6.041GlyLeu: 6.041 ± 0.079
2.059GlyMet: 2.059 ± 0.045
3.62GlyAsn: 3.62 ± 0.061
1.281GlyPro: 1.281 ± 0.031
2.366GlyGln: 2.366 ± 0.046
3.151GlyArg: 3.151 ± 0.062
3.856GlySer: 3.856 ± 0.066
3.959GlyThr: 3.959 ± 0.063
4.708GlyVal: 4.708 ± 0.069
0.924GlyTrp: 0.924 ± 0.029
3.282GlyTyr: 3.282 ± 0.058
0.0GlyXaa: 0.0 ± 0.0
His
1.048HisAla: 1.048 ± 0.028
0.261HisCys: 0.261 ± 0.015
0.755HisAsp: 0.755 ± 0.025
0.955HisGlu: 0.955 ± 0.029
1.112HisPhe: 1.112 ± 0.033
1.024HisGly: 1.024 ± 0.029
0.44HisHis: 0.44 ± 0.017
1.399HisIle: 1.399 ± 0.029
0.941HisLys: 0.941 ± 0.028
1.821HisLeu: 1.821 ± 0.042
0.414HisMet: 0.414 ± 0.02
0.836HisAsn: 0.836 ± 0.025
1.03HisPro: 1.03 ± 0.033
0.583HisGln: 0.583 ± 0.02
0.999HisArg: 0.999 ± 0.032
1.045HisSer: 1.045 ± 0.029
1.059HisThr: 1.059 ± 0.031
0.9HisVal: 0.9 ± 0.027
0.248HisTrp: 0.248 ± 0.015
0.928HisTyr: 0.928 ± 0.025
0.0HisXaa: 0.0 ± 0.0
Ile
5.201IleAla: 5.201 ± 0.073
1.016IleCys: 1.016 ± 0.033
4.271IleAsp: 4.271 ± 0.06
4.473IleGlu: 4.473 ± 0.065
3.124IlePhe: 3.124 ± 0.061
4.961IleGly: 4.961 ± 0.074
1.384IleHis: 1.384 ± 0.043
4.455IleIle: 4.455 ± 0.083
3.818IleLys: 3.818 ± 0.053
6.586IleLeu: 6.586 ± 0.087
1.431IleMet: 1.431 ± 0.032
3.055IleAsn: 3.055 ± 0.055
3.371IlePro: 3.371 ± 0.061
2.434IleGln: 2.434 ± 0.042
4.124IleArg: 4.124 ± 0.064
4.534IleSer: 4.534 ± 0.068
4.101IleThr: 4.101 ± 0.055
4.72IleVal: 4.72 ± 0.074
0.693IleTrp: 0.693 ± 0.025
2.811IleTyr: 2.811 ± 0.049
0.0IleXaa: 0.0 ± 0.0
Lys
4.933LysAla: 4.933 ± 0.069
0.513LysCys: 0.513 ± 0.023
3.671LysAsp: 3.671 ± 0.061
5.368LysGlu: 5.368 ± 0.073
2.246LysPhe: 2.246 ± 0.04
4.259LysGly: 4.259 ± 0.063
1.064LysHis: 1.064 ± 0.029
4.841LysIle: 4.841 ± 0.069
4.932LysLys: 4.932 ± 0.078
5.48LysLeu: 5.48 ± 0.078
2.059LysMet: 2.059 ± 0.044
3.655LysAsn: 3.655 ± 0.067
2.0LysPro: 2.0 ± 0.041
2.505LysGln: 2.505 ± 0.048
3.136LysArg: 3.136 ± 0.052
3.293LysSer: 3.293 ± 0.053
3.632LysThr: 3.632 ± 0.047
4.398LysVal: 4.398 ± 0.06
0.764LysTrp: 0.764 ± 0.03
3.122LysTyr: 3.122 ± 0.051
0.0LysXaa: 0.0 ± 0.0
Leu
6.345LeuAla: 6.345 ± 0.072
1.262LeuCys: 1.262 ± 0.034
4.627LeuAsp: 4.627 ± 0.07
5.978LeuGlu: 5.978 ± 0.077
4.774LeuPhe: 4.774 ± 0.071
5.916LeuGly: 5.916 ± 0.077
1.635LeuHis: 1.635 ± 0.04
5.921LeuIle: 5.921 ± 0.087
7.118LeuLys: 7.118 ± 0.073
9.368LeuLeu: 9.368 ± 0.124
2.284LeuMet: 2.284 ± 0.047
4.794LeuAsn: 4.794 ± 0.063
4.216LeuPro: 4.216 ± 0.059
3.616LeuGln: 3.616 ± 0.065
4.426LeuArg: 4.426 ± 0.065
6.65LeuSer: 6.65 ± 0.079
5.422LeuThr: 5.422 ± 0.07
5.238LeuVal: 5.238 ± 0.074
1.079LeuTrp: 1.079 ± 0.03
3.793LeuTyr: 3.793 ± 0.056
0.0LeuXaa: 0.0 ± 0.0
Met
1.966MetAla: 1.966 ± 0.044
0.246MetCys: 0.246 ± 0.013
1.339MetAsp: 1.339 ± 0.031
1.792MetGlu: 1.792 ± 0.039
0.994MetPhe: 0.994 ± 0.03
1.664MetGly: 1.664 ± 0.041
0.383MetHis: 0.383 ± 0.019
1.706MetIle: 1.706 ± 0.041
2.443MetLys: 2.443 ± 0.044
2.417MetLeu: 2.417 ± 0.05
0.688MetMet: 0.688 ± 0.024
1.532MetAsn: 1.532 ± 0.037
1.072MetPro: 1.072 ± 0.03
1.009MetGln: 1.009 ± 0.027
1.234MetArg: 1.234 ± 0.031
1.388MetSer: 1.388 ± 0.034
1.463MetThr: 1.463 ± 0.033
1.482MetVal: 1.482 ± 0.038
0.242MetTrp: 0.242 ± 0.016
0.856MetTyr: 0.856 ± 0.025
0.0MetXaa: 0.0 ± 0.0
Asn
3.175AsnAla: 3.175 ± 0.055
0.506AsnCys: 0.506 ± 0.022
2.357AsnAsp: 2.357 ± 0.042
2.963AsnGlu: 2.963 ± 0.053
2.214AsnPhe: 2.214 ± 0.05
3.394AsnGly: 3.394 ± 0.057
0.891AsnHis: 0.891 ± 0.031
3.857AsnIle: 3.857 ± 0.064
3.005AsnLys: 3.005 ± 0.054
4.364AsnLeu: 4.364 ± 0.063
1.323AsnMet: 1.323 ± 0.036
2.433AsnAsn: 2.433 ± 0.053
2.431AsnPro: 2.431 ± 0.046
1.629AsnGln: 1.629 ± 0.039
2.842AsnArg: 2.842 ± 0.051
2.71AsnSer: 2.71 ± 0.051
2.798AsnThr: 2.798 ± 0.047
2.838AsnVal: 2.838 ± 0.047
0.635AsnTrp: 0.635 ± 0.021
2.357AsnTyr: 2.357 ± 0.048
0.0AsnXaa: 0.0 ± 0.0
Pro
2.925ProAla: 2.925 ± 0.044
0.408ProCys: 0.408 ± 0.02
2.671ProAsp: 2.671 ± 0.053
3.716ProGlu: 3.716 ± 0.055
1.726ProPhe: 1.726 ± 0.041
2.823ProGly: 2.823 ± 0.052
0.606ProHis: 0.606 ± 0.024
1.993ProIle: 1.993 ± 0.041
1.787ProLys: 1.787 ± 0.037
3.223ProLeu: 3.223 ± 0.048
0.85ProMet: 0.85 ± 0.027
1.462ProAsn: 1.462 ± 0.041
0.835ProPro: 0.835 ± 0.031
1.366ProGln: 1.366 ± 0.033
1.398ProArg: 1.398 ± 0.037
1.963ProSer: 1.963 ± 0.043
1.781ProThr: 1.781 ± 0.037
3.235ProVal: 3.235 ± 0.05
0.415ProTrp: 0.415 ± 0.018
1.66ProTyr: 1.66 ± 0.035
0.0ProXaa: 0.0 ± 0.0
Gln
2.614GlnAla: 2.614 ± 0.059
0.302GlnCys: 0.302 ± 0.016
1.631GlnAsp: 1.631 ± 0.042
2.829GlnGlu: 2.829 ± 0.051
1.321GlnPhe: 1.321 ± 0.033
2.291GlnGly: 2.291 ± 0.045
0.65GlnHis: 0.65 ± 0.024
2.393GlnIle: 2.393 ± 0.045
2.597GlnLys: 2.597 ± 0.043
3.574GlnLeu: 3.574 ± 0.061
0.966GlnMet: 0.966 ± 0.029
1.799GlnAsn: 1.799 ± 0.044
1.23GlnPro: 1.23 ± 0.03
1.655GlnGln: 1.655 ± 0.049
1.651GlnArg: 1.651 ± 0.041
1.706GlnSer: 1.706 ± 0.038
1.935GlnThr: 1.935 ± 0.046
2.412GlnVal: 2.412 ± 0.047
0.411GlnTrp: 0.411 ± 0.018
1.377GlnTyr: 1.377 ± 0.033
0.0GlnXaa: 0.0 ± 0.0
Arg
2.636ArgAla: 2.636 ± 0.052
0.515ArgCys: 0.515 ± 0.023
2.331ArgAsp: 2.331 ± 0.044
3.593ArgGlu: 3.593 ± 0.06
2.503ArgPhe: 2.503 ± 0.044
2.694ArgGly: 2.694 ± 0.048
1.049ArgHis: 1.049 ± 0.033
4.019ArgIle: 4.019 ± 0.063
3.767ArgLys: 3.767 ± 0.064
5.229ArgLeu: 5.229 ± 0.078
1.524ArgMet: 1.524 ± 0.035
2.558ArgAsn: 2.558 ± 0.047
1.785ArgPro: 1.785 ± 0.045
2.257ArgGln: 2.257 ± 0.055
2.412ArgArg: 2.412 ± 0.049
2.359ArgSer: 2.359 ± 0.044
2.342ArgThr: 2.342 ± 0.047
2.883ArgVal: 2.883 ± 0.05
0.705ArgTrp: 0.705 ± 0.023
2.61ArgTyr: 2.61 ± 0.048
0.0ArgXaa: 0.0 ± 0.0
Ser
3.899SerAla: 3.899 ± 0.063
0.843SerCys: 0.843 ± 0.022
3.203SerAsp: 3.203 ± 0.057
3.647SerGlu: 3.647 ± 0.06
3.301SerPhe: 3.301 ± 0.062
4.644SerGly: 4.644 ± 0.061
0.984SerHis: 0.984 ± 0.03
3.876SerIle: 3.876 ± 0.059
3.026SerLys: 3.026 ± 0.054
5.765SerLeu: 5.765 ± 0.077
1.366SerMet: 1.366 ± 0.033
2.414SerAsn: 2.414 ± 0.051
2.233SerPro: 2.233 ± 0.043
1.763SerGln: 1.763 ± 0.034
2.787SerArg: 2.787 ± 0.049
3.623SerSer: 3.623 ± 0.08
2.902SerThr: 2.902 ± 0.054
4.259SerVal: 4.259 ± 0.057
0.805SerTrp: 0.805 ± 0.026
2.769SerTyr: 2.769 ± 0.06
0.0SerXaa: 0.0 ± 0.0
Thr
3.976ThrAla: 3.976 ± 0.064
0.572ThrCys: 0.572 ± 0.022
3.554ThrAsp: 3.554 ± 0.06
3.531ThrGlu: 3.531 ± 0.058
2.566ThrPhe: 2.566 ± 0.047
4.537ThrGly: 4.537 ± 0.071
0.982ThrHis: 0.982 ± 0.03
3.779ThrIle: 3.779 ± 0.057
2.558ThrLys: 2.558 ± 0.052
5.513ThrLeu: 5.513 ± 0.068
1.095ThrMet: 1.095 ± 0.031
2.117ThrAsn: 2.117 ± 0.04
2.604ThrPro: 2.604 ± 0.05
1.683ThrGln: 1.683 ± 0.04
2.263ThrArg: 2.263 ± 0.046
3.115ThrSer: 3.115 ± 0.06
3.257ThrThr: 3.257 ± 0.061
4.081ThrVal: 4.081 ± 0.06
0.598ThrTrp: 0.598 ± 0.025
2.353ThrTyr: 2.353 ± 0.052
0.0ThrXaa: 0.0 ± 0.0
Val
4.53ValAla: 4.53 ± 0.068
0.978ValCys: 0.978 ± 0.032
3.521ValAsp: 3.521 ± 0.057
4.056ValGlu: 4.056 ± 0.066
3.237ValPhe: 3.237 ± 0.056
4.088ValGly: 4.088 ± 0.072
0.99ValHis: 0.99 ± 0.031
4.604ValIle: 4.604 ± 0.068
4.418ValLys: 4.418 ± 0.061
6.257ValLeu: 6.257 ± 0.068
1.681ValMet: 1.681 ± 0.038
3.266ValAsn: 3.266 ± 0.052
2.373ValPro: 2.373 ± 0.047
1.978ValGln: 1.978 ± 0.042
3.267ValArg: 3.267 ± 0.061
4.227ValSer: 4.227 ± 0.065
3.709ValThr: 3.709 ± 0.064
4.843ValVal: 4.843 ± 0.079
0.849ValTrp: 0.849 ± 0.03
2.796ValTyr: 2.796 ± 0.05
0.0ValXaa: 0.0 ± 0.0
Trp
0.745TrpAla: 0.745 ± 0.026
0.201TrpCys: 0.201 ± 0.013
0.655TrpAsp: 0.655 ± 0.027
0.814TrpGlu: 0.814 ± 0.026
0.588TrpPhe: 0.588 ± 0.022
0.97TrpGly: 0.97 ± 0.029
0.227TrpHis: 0.227 ± 0.015
0.842TrpIle: 0.842 ± 0.026
0.902TrpLys: 0.902 ± 0.031
1.28TrpLeu: 1.28 ± 0.034
0.401TrpMet: 0.401 ± 0.019
0.715TrpAsn: 0.715 ± 0.026
0.269TrpPro: 0.269 ± 0.014
0.559TrpGln: 0.559 ± 0.022
0.63TrpArg: 0.63 ± 0.023
0.629TrpSer: 0.629 ± 0.023
0.58TrpThr: 0.58 ± 0.023
0.68TrpVal: 0.68 ± 0.025
0.206TrpTrp: 0.206 ± 0.013
0.564TrpTyr: 0.564 ± 0.025
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.055TyrAla: 3.055 ± 0.054
0.564TyrCys: 0.564 ± 0.023
2.605TyrAsp: 2.605 ± 0.044
2.615TyrGlu: 2.615 ± 0.042
2.276TyrPhe: 2.276 ± 0.048
2.946TyrGly: 2.946 ± 0.048
0.871TyrHis: 0.871 ± 0.025
2.854TyrIle: 2.854 ± 0.051
2.677TyrLys: 2.677 ± 0.053
4.085TyrLeu: 4.085 ± 0.065
1.044TyrMet: 1.044 ± 0.029
2.536TyrAsn: 2.536 ± 0.058
1.834TyrPro: 1.834 ± 0.039
1.479TyrGln: 1.479 ± 0.033
2.643TyrArg: 2.643 ± 0.045
2.776TyrSer: 2.776 ± 0.05
2.746TyrThr: 2.746 ± 0.049
2.473TyrVal: 2.473 ± 0.047
0.597TyrTrp: 0.597 ± 0.024
2.252TyrTyr: 2.252 ± 0.047
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3479 proteins (1258135 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski