Corynebacterium sp. HMSC04H06

Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Actinobacteria; Actinomycetia; Corynebacteriales; Corynebacteriaceae; Corynebacterium; unclassified Corynebacterium

Average proteome isoelectric point is 5.88

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2014 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1F1L8G1|A0A1F1L8G1_9CORY Uncharacterized protein OS=Corynebacterium sp. HMSC04H06 OX=1581050 GN=HMPREF3067_00760 PE=4 SV=1
MM1 pKa = 7.2KK2 pKa = 9.99RR3 pKa = 11.84AAIATAALALALTGCSAADD22 pKa = 3.86PEE24 pKa = 4.39PTADD28 pKa = 3.49GTVSQDD34 pKa = 3.19TFLTAHH40 pKa = 6.93GLVDD44 pKa = 3.8MDD46 pKa = 3.54AVEE49 pKa = 5.62IIDD52 pKa = 3.65HH53 pKa = 7.28LDD55 pKa = 3.38RR56 pKa = 11.84QKK58 pKa = 9.9VTEE61 pKa = 4.56RR62 pKa = 11.84PTDD65 pKa = 4.58LIASVRR71 pKa = 11.84ADD73 pKa = 3.78EE74 pKa = 5.15LLLSSDD80 pKa = 3.74DD81 pKa = 3.88QEE83 pKa = 4.73VVLDD87 pKa = 4.2LPDD90 pKa = 3.53NQTYY94 pKa = 10.58VSIAPYY100 pKa = 8.84LTSTHH105 pKa = 6.73DD106 pKa = 3.63CFYY109 pKa = 11.16HH110 pKa = 7.35SLTTCQGEE118 pKa = 4.63LDD120 pKa = 4.0NEE122 pKa = 4.81DD123 pKa = 3.4IQVTITDD130 pKa = 3.75EE131 pKa = 4.08ATGEE135 pKa = 4.27VLVDD139 pKa = 3.43EE140 pKa = 4.91ATTTFDD146 pKa = 3.45NGFIGFWLPDD156 pKa = 3.78DD157 pKa = 3.77ATGLIEE163 pKa = 4.24VSYY166 pKa = 10.53QGRR169 pKa = 11.84TGTAEE174 pKa = 4.15FSTADD179 pKa = 3.86DD180 pKa = 4.25GATCVTDD187 pKa = 3.36LHH189 pKa = 6.16LTT191 pKa = 3.66

Molecular weight: 20.46 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1F1L0K4|A0A1F1L0K4_9CORY Cysteine synthase OS=Corynebacterium sp. HMSC04H06 OX=1581050 GN=HMPREF3067_04820 PE=3 SV=1
MM1 pKa = 6.11THH3 pKa = 7.29KK4 pKa = 10.32IKK6 pKa = 10.37PDD8 pKa = 3.02EE9 pKa = 4.07VFAARR14 pKa = 11.84RR15 pKa = 11.84RR16 pKa = 11.84RR17 pKa = 11.84RR18 pKa = 11.84VGIFILLAVLMLIAVVLSIVLGQYY42 pKa = 8.17YY43 pKa = 9.61VPLQDD48 pKa = 5.08LVPILLGSDD57 pKa = 3.2HH58 pKa = 6.85HH59 pKa = 7.23AGLAASVVWDD69 pKa = 3.25IRR71 pKa = 11.84LPRR74 pKa = 11.84ILLGFLVGACLGVAGTLMQAVFANPLAEE102 pKa = 4.0PSIIGVTSGAGVGAALAIVFNIAFLGTFTVPFFAFLSALVAAGLIYY148 pKa = 10.47QLARR152 pKa = 11.84SSGRR156 pKa = 11.84VAVINLVLTGIAVNAVCGAIISFMVYY182 pKa = 10.44LAPTTSRR189 pKa = 11.84EE190 pKa = 4.06EE191 pKa = 3.82IIFWQMGSLNGAQWKK206 pKa = 6.86HH207 pKa = 4.49TWVVLPIAIVGIAVALRR224 pKa = 11.84LGGALDD230 pKa = 3.63VLALGEE236 pKa = 4.14RR237 pKa = 11.84AAGHH241 pKa = 5.56TGINVSRR248 pKa = 11.84LRR250 pKa = 11.84VIAIVASAILTAGAVAFAGLIGFVGLIVPHH280 pKa = 6.68LFRR283 pKa = 11.84TVVGPEE289 pKa = 3.59NHH291 pKa = 6.54LLIPASALGGAVLIGLADD309 pKa = 3.45VAARR313 pKa = 11.84TMIAFADD320 pKa = 4.04LPIGIFTALVGGPTFFILLRR340 pKa = 11.84RR341 pKa = 11.84MMRR344 pKa = 11.84KK345 pKa = 9.6GMHH348 pKa = 5.9AA349 pKa = 3.47

Molecular weight: 36.47 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2014

0

2014

663308

40

3035

329.3

35.59

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

12.275 ± 0.077

0.707 ± 0.014

6.187 ± 0.054

6.327 ± 0.059

3.365 ± 0.033

8.591 ± 0.042

2.123 ± 0.025

4.677 ± 0.04

3.09 ± 0.04

9.663 ± 0.064

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.145 ± 0.022

2.81 ± 0.032

5.044 ± 0.04

3.539 ± 0.03

6.191 ± 0.047

5.59 ± 0.035

5.765 ± 0.038

8.216 ± 0.046

1.399 ± 0.024

2.296 ± 0.028
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski