Amino acid dipepetide frequency for Hubei diptera virus 12

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.362AlaAla: 3.362 ± 1.392
0.672AlaCys: 0.672 ± 0.588
3.362AlaAsp: 3.362 ± 0.985
2.017AlaGlu: 2.017 ± 0.805
4.035AlaPhe: 4.035 ± 0.747
3.362AlaGly: 3.362 ± 0.388
2.017AlaHis: 2.017 ± 0.961
2.017AlaIle: 2.017 ± 0.275
1.345AlaLys: 1.345 ± 0.579
2.017AlaLeu: 2.017 ± 0.275
2.017AlaMet: 2.017 ± 1.367
3.362AlaAsn: 3.362 ± 1.587
1.345AlaPro: 1.345 ± 1.325
2.69AlaGln: 2.69 ± 0.936
4.035AlaArg: 4.035 ± 1.35
7.397AlaSer: 7.397 ± 3.999
6.052AlaThr: 6.052 ± 1.911
6.052AlaVal: 6.052 ± 1.271
0.672AlaTrp: 0.672 ± 0.456
0.672AlaTyr: 0.672 ± 0.588
0.0AlaXaa: 0.0 ± 0.0
Cys
0.672CysAla: 0.672 ± 0.456
0.672CysCys: 0.672 ± 0.456
2.017CysAsp: 2.017 ± 1.367
0.672CysGlu: 0.672 ± 0.456
1.345CysPhe: 1.345 ± 0.579
1.345CysGly: 1.345 ± 0.717
0.0CysHis: 0.0 ± 0.0
0.672CysIle: 0.672 ± 0.456
2.017CysLys: 2.017 ± 1.367
2.69CysLeu: 2.69 ± 0.936
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.672CysPro: 0.672 ± 0.588
0.672CysGln: 0.672 ± 0.588
0.0CysArg: 0.0 ± 0.0
3.362CysSer: 3.362 ± 2.099
2.017CysThr: 2.017 ± 0.275
3.362CysVal: 3.362 ± 2.447
0.672CysTrp: 0.672 ± 0.588
0.672CysTyr: 0.672 ± 0.588
0.0CysXaa: 0.0 ± 0.0
Asp
2.017AspAla: 2.017 ± 0.275
2.017AspCys: 2.017 ± 0.275
3.362AspAsp: 3.362 ± 2.447
2.69AspGlu: 2.69 ± 0.936
2.017AspPhe: 2.017 ± 0.805
3.362AspGly: 3.362 ± 1.556
1.345AspHis: 1.345 ± 0.579
3.362AspIle: 3.362 ± 0.985
3.362AspLys: 3.362 ± 1.556
4.035AspLeu: 4.035 ± 0.457
2.017AspMet: 2.017 ± 0.388
1.345AspAsn: 1.345 ± 0.717
3.362AspPro: 3.362 ± 2.212
1.345AspGln: 1.345 ± 1.325
2.017AspArg: 2.017 ± 0.805
4.707AspSer: 4.707 ± 2.477
5.38AspThr: 5.38 ± 0.482
4.035AspVal: 4.035 ± 1.333
2.69AspTrp: 2.69 ± 1.866
0.672AspTyr: 0.672 ± 0.663
0.0AspXaa: 0.0 ± 0.0
Glu
2.69GluAla: 2.69 ± 0.9
0.672GluCys: 0.672 ± 0.456
4.035GluAsp: 4.035 ± 0.457
2.69GluGlu: 2.69 ± 1.173
1.345GluPhe: 1.345 ± 0.579
2.017GluGly: 2.017 ± 0.712
1.345GluHis: 1.345 ± 0.717
0.672GluIle: 0.672 ± 0.456
2.69GluLys: 2.69 ± 1.823
4.707GluLeu: 4.707 ± 2.128
2.69GluMet: 2.69 ± 1.587
1.345GluAsn: 1.345 ± 0.912
4.035GluPro: 4.035 ± 1.61
3.362GluGln: 3.362 ± 1.116
2.69GluArg: 2.69 ± 1.523
2.69GluSer: 2.69 ± 1.173
3.362GluThr: 3.362 ± 1.527
3.362GluVal: 3.362 ± 1.116
1.345GluTrp: 1.345 ± 0.468
0.672GluTyr: 0.672 ± 0.663
0.0GluXaa: 0.0 ± 0.0
Phe
2.69PheAla: 2.69 ± 0.23
2.017PheCys: 2.017 ± 1.249
2.69PheAsp: 2.69 ± 1.433
2.017PheGlu: 2.017 ± 0.961
0.0PhePhe: 0.0 ± 0.0
0.672PheGly: 0.672 ± 0.456
1.345PheHis: 1.345 ± 0.912
3.362PheIle: 3.362 ± 1.707
2.69PheLys: 2.69 ± 0.713
1.345PheLeu: 1.345 ± 0.912
1.345PheMet: 1.345 ± 0.579
0.672PheAsn: 0.672 ± 0.663
0.672PhePro: 0.672 ± 0.663
0.672PheGln: 0.672 ± 0.588
1.345PheArg: 1.345 ± 1.325
1.345PheSer: 1.345 ± 0.717
3.362PheThr: 3.362 ± 0.388
4.035PheVal: 4.035 ± 2.735
2.017PheTrp: 2.017 ± 0.805
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.707GlyAla: 4.707 ± 1.841
0.672GlyCys: 0.672 ± 0.663
2.017GlyAsp: 2.017 ± 1.158
6.052GlyGlu: 6.052 ± 1.529
1.345GlyPhe: 1.345 ± 0.717
3.362GlyGly: 3.362 ± 1.8
0.0GlyHis: 0.0 ± 0.0
2.017GlyIle: 2.017 ± 0.275
2.69GlyLys: 2.69 ± 0.9
7.397GlyLeu: 7.397 ± 1.572
1.345GlyMet: 1.345 ± 0.912
4.035GlyAsn: 4.035 ± 0.457
2.69GlyPro: 2.69 ± 0.713
2.69GlyGln: 2.69 ± 1.823
2.017GlyArg: 2.017 ± 1.249
5.38GlySer: 5.38 ± 1.872
2.69GlyThr: 2.69 ± 2.353
5.38GlyVal: 5.38 ± 2.116
3.362GlyTrp: 3.362 ± 0.985
3.362GlyTyr: 3.362 ± 0.388
0.0GlyXaa: 0.0 ± 0.0
His
3.362HisAla: 3.362 ± 0.985
0.0HisCys: 0.0 ± 0.0
1.345HisAsp: 1.345 ± 0.579
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.345HisGly: 1.345 ± 0.717
0.672HisHis: 0.672 ± 0.588
0.672HisIle: 0.672 ± 0.456
2.69HisLys: 2.69 ± 0.713
0.672HisLeu: 0.672 ± 0.588
1.345HisMet: 1.345 ± 1.325
0.0HisAsn: 0.0 ± 0.0
2.017HisPro: 2.017 ± 1.367
1.345HisGln: 1.345 ± 1.177
4.035HisArg: 4.035 ± 0.747
2.017HisSer: 2.017 ± 0.712
0.672HisThr: 0.672 ± 0.456
2.69HisVal: 2.69 ± 0.936
1.345HisTrp: 1.345 ± 0.579
1.345HisTyr: 1.345 ± 0.717
0.0HisXaa: 0.0 ± 0.0
Ile
4.707IleAla: 4.707 ± 0.222
0.0IleCys: 0.0 ± 0.0
2.69IleAsp: 2.69 ± 1.159
0.672IleGlu: 0.672 ± 0.456
1.345IlePhe: 1.345 ± 0.579
3.362IleGly: 3.362 ± 1.278
2.017IleHis: 2.017 ± 1.765
0.672IleIle: 0.672 ± 0.663
1.345IleLys: 1.345 ± 1.325
3.362IleLeu: 3.362 ± 0.668
1.345IleMet: 1.345 ± 0.912
1.345IleAsn: 1.345 ± 0.717
5.38IlePro: 5.38 ± 2.029
0.0IleGln: 0.0 ± 0.0
3.362IleArg: 3.362 ± 0.985
3.362IleSer: 3.362 ± 0.985
3.362IleThr: 3.362 ± 0.388
4.035IleVal: 4.035 ± 0.55
0.672IleTrp: 0.672 ± 0.456
2.017IleTyr: 2.017 ± 1.158
0.0IleXaa: 0.0 ± 0.0
Lys
2.69LysAla: 2.69 ± 0.936
0.672LysCys: 0.672 ± 0.456
1.345LysAsp: 1.345 ± 0.579
2.017LysGlu: 2.017 ± 0.805
0.672LysPhe: 0.672 ± 0.588
2.017LysGly: 2.017 ± 1.158
1.345LysHis: 1.345 ± 0.717
1.345LysIle: 1.345 ± 0.579
3.362LysLys: 3.362 ± 0.668
6.052LysLeu: 6.052 ± 1.696
1.345LysMet: 1.345 ± 0.912
3.362LysAsn: 3.362 ± 1.587
2.017LysPro: 2.017 ± 0.961
3.362LysGln: 3.362 ± 0.69
2.017LysArg: 2.017 ± 0.275
4.035LysSer: 4.035 ± 1.61
4.035LysThr: 4.035 ± 1.425
5.38LysVal: 5.38 ± 1.403
1.345LysTrp: 1.345 ± 0.717
2.017LysTyr: 2.017 ± 1.249
0.0LysXaa: 0.0 ± 0.0
Leu
4.707LeuAla: 4.707 ± 1.027
0.672LeuCys: 0.672 ± 0.663
6.052LeuAsp: 6.052 ± 2.417
8.07LeuGlu: 8.07 ± 0.691
6.725LeuPhe: 6.725 ± 3.97
3.362LeuGly: 3.362 ± 1.326
2.017LeuHis: 2.017 ± 1.249
4.707LeuIle: 4.707 ± 0.906
2.69LeuLys: 2.69 ± 1.523
11.432LeuLeu: 11.432 ± 1.177
3.362LeuMet: 3.362 ± 0.388
2.017LeuAsn: 2.017 ± 0.275
2.017LeuPro: 2.017 ± 1.367
1.345LeuGln: 1.345 ± 0.579
4.035LeuArg: 4.035 ± 1.333
3.362LeuSer: 3.362 ± 0.388
6.052LeuThr: 6.052 ± 2.137
10.087LeuVal: 10.087 ± 3.562
1.345LeuTrp: 1.345 ± 0.579
2.017LeuTyr: 2.017 ± 1.158
0.0LeuXaa: 0.0 ± 0.0
Met
0.672MetAla: 0.672 ± 0.456
0.0MetCys: 0.0 ± 0.0
2.017MetAsp: 2.017 ± 0.805
2.69MetGlu: 2.69 ± 1.159
0.672MetPhe: 0.672 ± 0.456
2.69MetGly: 2.69 ± 0.9
0.672MetHis: 0.672 ± 0.456
0.672MetIle: 0.672 ± 0.456
0.672MetLys: 0.672 ± 0.456
3.362MetLeu: 3.362 ± 1.707
0.0MetMet: 0.0 ± 0.0
2.017MetAsn: 2.017 ± 0.275
0.672MetPro: 0.672 ± 0.588
2.017MetGln: 2.017 ± 0.805
3.362MetArg: 3.362 ± 1.326
1.345MetSer: 1.345 ± 0.579
2.017MetThr: 2.017 ± 1.132
3.362MetVal: 3.362 ± 1.392
0.672MetTrp: 0.672 ± 0.663
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.672AsnAla: 0.672 ± 0.456
2.69AsnCys: 2.69 ± 0.23
2.69AsnAsp: 2.69 ± 0.23
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
0.0AsnGly: 0.0 ± 0.0
0.672AsnHis: 0.672 ± 0.456
2.017AsnIle: 2.017 ± 0.275
0.672AsnLys: 0.672 ± 0.663
2.69AsnLeu: 2.69 ± 1.433
0.672AsnMet: 0.672 ± 0.822
0.672AsnAsn: 0.672 ± 0.456
2.017AsnPro: 2.017 ± 1.249
1.345AsnGln: 1.345 ± 0.468
2.69AsnArg: 2.69 ± 0.713
4.707AsnSer: 4.707 ± 1.154
0.672AsnThr: 0.672 ± 0.663
4.035AsnVal: 4.035 ± 1.425
1.345AsnTrp: 1.345 ± 0.579
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.69ProAla: 2.69 ± 0.936
1.345ProCys: 1.345 ± 0.468
2.69ProAsp: 2.69 ± 0.936
2.69ProGlu: 2.69 ± 1.159
1.345ProPhe: 1.345 ± 0.468
4.707ProGly: 4.707 ± 1.244
2.017ProHis: 2.017 ± 1.158
4.035ProIle: 4.035 ± 0.747
0.672ProLys: 0.672 ± 0.456
4.035ProLeu: 4.035 ± 0.747
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
2.017ProPro: 2.017 ± 0.275
1.345ProGln: 1.345 ± 0.468
2.017ProArg: 2.017 ± 0.961
6.725ProSer: 6.725 ± 1.525
4.035ProThr: 4.035 ± 0.97
6.725ProVal: 6.725 ± 1.525
0.0ProTrp: 0.0 ± 0.0
1.345ProTyr: 1.345 ± 0.717
0.0ProXaa: 0.0 ± 0.0
Gln
1.345GlnAla: 1.345 ± 0.468
2.017GlnCys: 2.017 ± 0.712
0.672GlnAsp: 0.672 ± 0.588
2.69GlnGlu: 2.69 ± 0.713
1.345GlnPhe: 1.345 ± 0.468
3.362GlnGly: 3.362 ± 1.392
2.69GlnHis: 2.69 ± 1.523
2.69GlnIle: 2.69 ± 0.9
4.035GlnLys: 4.035 ± 1.333
1.345GlnLeu: 1.345 ± 0.579
1.345GlnMet: 1.345 ± 0.717
2.017GlnAsn: 2.017 ± 0.805
1.345GlnPro: 1.345 ± 0.468
1.345GlnGln: 1.345 ± 0.468
3.362GlnArg: 3.362 ± 1.116
2.017GlnSer: 2.017 ± 0.805
2.017GlnThr: 2.017 ± 0.961
5.38GlnVal: 5.38 ± 2.201
0.672GlnTrp: 0.672 ± 0.663
0.672GlnTyr: 0.672 ± 0.588
0.0GlnXaa: 0.0 ± 0.0
Arg
2.017ArgAla: 2.017 ± 1.988
2.017ArgCys: 2.017 ± 0.712
2.69ArgAsp: 2.69 ± 1.433
2.017ArgGlu: 2.017 ± 0.712
2.69ArgPhe: 2.69 ± 0.9
6.725ArgGly: 6.725 ± 1.636
1.345ArgHis: 1.345 ± 0.912
2.017ArgIle: 2.017 ± 0.961
2.69ArgLys: 2.69 ± 0.936
8.742ArgLeu: 8.742 ± 1.378
0.672ArgMet: 0.672 ± 0.456
2.017ArgAsn: 2.017 ± 1.988
0.672ArgPro: 0.672 ± 0.588
4.035ArgGln: 4.035 ± 0.97
4.035ArgArg: 4.035 ± 1.52
4.035ArgSer: 4.035 ± 1.12
2.69ArgThr: 2.69 ± 1.823
6.052ArgVal: 6.052 ± 1.529
0.672ArgTrp: 0.672 ± 0.588
0.672ArgTyr: 0.672 ± 0.663
0.0ArgXaa: 0.0 ± 0.0
Ser
5.38SerAla: 5.38 ± 3.026
0.672SerCys: 0.672 ± 0.588
4.035SerAsp: 4.035 ± 1.857
2.017SerGlu: 2.017 ± 1.132
3.362SerPhe: 3.362 ± 1.116
6.725SerGly: 6.725 ± 0.776
1.345SerHis: 1.345 ± 0.579
3.362SerIle: 3.362 ± 1.527
0.672SerLys: 0.672 ± 0.456
6.052SerLeu: 6.052 ± 1.538
3.362SerMet: 3.362 ± 1.278
1.345SerAsn: 1.345 ± 1.177
4.707SerPro: 4.707 ± 0.826
7.397SerGln: 7.397 ± 0.714
6.052SerArg: 6.052 ± 2.622
8.742SerSer: 8.742 ± 0.704
4.035SerThr: 4.035 ± 1.12
6.052SerVal: 6.052 ± 1.053
0.672SerTrp: 0.672 ± 0.663
3.362SerTyr: 3.362 ± 0.69
0.0SerXaa: 0.0 ± 0.0
Thr
2.69ThrAla: 2.69 ± 1.523
2.017ThrCys: 2.017 ± 0.961
2.017ThrAsp: 2.017 ± 0.275
2.017ThrGlu: 2.017 ± 0.712
2.017ThrPhe: 2.017 ± 0.275
5.38ThrGly: 5.38 ± 1.872
4.035ThrHis: 4.035 ± 0.747
3.362ThrIle: 3.362 ± 1.8
4.707ThrLys: 4.707 ± 2.412
6.052ThrLeu: 6.052 ± 1.165
0.672ThrMet: 0.672 ± 0.456
2.017ThrAsn: 2.017 ± 0.275
6.052ThrPro: 6.052 ± 1.271
4.035ThrGln: 4.035 ± 0.457
2.69ThrArg: 2.69 ± 0.23
4.707ThrSer: 4.707 ± 0.906
4.707ThrThr: 4.707 ± 1.556
7.397ThrVal: 7.397 ± 1.733
1.345ThrTrp: 1.345 ± 0.912
0.672ThrTyr: 0.672 ± 0.588
0.0ThrXaa: 0.0 ± 0.0
Val
8.07ValAla: 8.07 ± 1.818
2.69ValCys: 2.69 ± 1.823
5.38ValAsp: 5.38 ± 2.2
6.052ValGlu: 6.052 ± 1.816
2.69ValPhe: 2.69 ± 1.101
7.397ValGly: 7.397 ± 3.395
2.017ValHis: 2.017 ± 0.712
1.345ValIle: 1.345 ± 0.468
10.087ValLys: 10.087 ± 2.908
6.052ValLeu: 6.052 ± 0.787
3.362ValMet: 3.362 ± 0.69
3.362ValAsn: 3.362 ± 2.212
6.052ValPro: 6.052 ± 1.696
3.362ValGln: 3.362 ± 1.278
2.69ValArg: 2.69 ± 0.713
6.725ValSer: 6.725 ± 1.636
6.052ValThr: 6.052 ± 1.696
11.432ValVal: 11.432 ± 1.377
0.0ValTrp: 0.0 ± 0.0
5.38ValTyr: 5.38 ± 2.86
0.0ValXaa: 0.0 ± 0.0
Trp
1.345TrpAla: 1.345 ± 0.468
0.672TrpCys: 0.672 ± 0.588
2.017TrpAsp: 2.017 ± 1.158
1.345TrpGlu: 1.345 ± 0.468
0.0TrpPhe: 0.0 ± 0.0
0.672TrpGly: 0.672 ± 0.456
0.0TrpHis: 0.0 ± 0.0
2.69TrpIle: 2.69 ± 1.159
0.0TrpLys: 0.0 ± 0.0
2.017TrpLeu: 2.017 ± 1.158
1.345TrpMet: 1.345 ± 1.325
0.0TrpAsn: 0.0 ± 0.0
1.345TrpPro: 1.345 ± 0.912
0.0TrpGln: 0.0 ± 0.0
2.017TrpArg: 2.017 ± 0.275
0.0TrpSer: 0.0 ± 0.0
4.035TrpThr: 4.035 ± 1.52
0.672TrpVal: 0.672 ± 0.663
0.0TrpTrp: 0.0 ± 0.0
0.672TrpTyr: 0.672 ± 0.588
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.017TyrAla: 2.017 ± 0.275
1.345TyrCys: 1.345 ± 0.717
2.017TyrAsp: 2.017 ± 1.132
0.0TyrGlu: 0.0 ± 0.0
1.345TyrPhe: 1.345 ± 0.468
1.345TyrGly: 1.345 ± 0.468
0.672TyrHis: 0.672 ± 0.663
3.362TyrIle: 3.362 ± 0.388
1.345TyrLys: 1.345 ± 0.579
2.017TyrLeu: 2.017 ± 1.158
0.672TyrMet: 0.672 ± 0.663
0.0TyrAsn: 0.0 ± 0.0
1.345TyrPro: 1.345 ± 1.325
0.0TyrGln: 0.0 ± 0.0
4.035TyrArg: 4.035 ± 0.457
2.69TyrSer: 2.69 ± 1.159
1.345TyrThr: 1.345 ± 1.177
0.672TyrVal: 0.672 ± 0.456
0.0TyrTrp: 0.0 ± 0.0
1.345TyrTyr: 1.345 ± 0.717
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1488 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski