Amino acid dipepetide frequency for Little cherry virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.019AlaAla: 4.019 ± 1.188
0.365AlaCys: 0.365 ± 0.27
2.009AlaAsp: 2.009 ± 0.735
2.009AlaGlu: 2.009 ± 0.708
2.558AlaPhe: 2.558 ± 0.683
1.644AlaGly: 1.644 ± 0.779
1.096AlaHis: 1.096 ± 0.381
4.202AlaIle: 4.202 ± 0.831
4.567AlaLys: 4.567 ± 0.906
4.932AlaLeu: 4.932 ± 1.517
1.644AlaMet: 1.644 ± 0.736
2.375AlaAsn: 2.375 ± 0.561
1.096AlaPro: 1.096 ± 0.36
1.461AlaGln: 1.461 ± 0.635
1.827AlaArg: 1.827 ± 0.692
3.836AlaSer: 3.836 ± 1.15
3.106AlaThr: 3.106 ± 0.419
2.558AlaVal: 2.558 ± 0.874
0.0AlaTrp: 0.0 ± 0.0
2.009AlaTyr: 2.009 ± 0.471
0.0AlaXaa: 0.0 ± 0.0
Cys
0.913CysAla: 0.913 ± 0.367
0.365CysCys: 0.365 ± 0.312
2.192CysAsp: 2.192 ± 0.42
1.096CysGlu: 1.096 ± 0.476
0.913CysPhe: 0.913 ± 0.55
0.731CysGly: 0.731 ± 0.364
0.365CysHis: 0.365 ± 0.255
0.913CysIle: 0.913 ± 0.304
1.279CysLys: 1.279 ± 0.322
3.106CysLeu: 3.106 ± 0.876
1.096CysMet: 1.096 ± 0.465
0.731CysAsn: 0.731 ± 0.51
0.731CysPro: 0.731 ± 0.356
0.548CysGln: 0.548 ± 0.232
0.913CysArg: 0.913 ± 0.291
0.731CysSer: 0.731 ± 0.577
0.365CysThr: 0.365 ± 0.182
0.913CysVal: 0.913 ± 0.283
0.183CysTrp: 0.183 ± 0.128
1.096CysTyr: 1.096 ± 0.404
0.0CysXaa: 0.0 ± 0.0
Asp
3.106AspAla: 3.106 ± 0.648
0.913AspCys: 0.913 ± 0.355
4.202AspAsp: 4.202 ± 0.975
5.48AspGlu: 5.48 ± 1.331
4.932AspPhe: 4.932 ± 0.627
3.471AspGly: 3.471 ± 0.851
1.096AspHis: 1.096 ± 0.743
5.48AspIle: 5.48 ± 0.573
5.298AspLys: 5.298 ± 1.168
6.577AspLeu: 6.577 ± 1.418
0.913AspMet: 0.913 ± 0.535
3.654AspAsn: 3.654 ± 0.642
0.913AspPro: 0.913 ± 0.411
1.096AspGln: 1.096 ± 0.382
3.471AspArg: 3.471 ± 0.464
5.298AspSer: 5.298 ± 0.746
3.106AspThr: 3.106 ± 0.333
4.202AspVal: 4.202 ± 0.473
0.548AspTrp: 0.548 ± 0.256
1.827AspTyr: 1.827 ± 0.98
0.0AspXaa: 0.0 ± 0.0
Glu
2.009GluAla: 2.009 ± 0.51
0.913GluCys: 0.913 ± 0.474
2.74GluAsp: 2.74 ± 0.713
2.923GluGlu: 2.923 ± 1.306
4.019GluPhe: 4.019 ± 0.977
1.279GluGly: 1.279 ± 0.387
1.644GluHis: 1.644 ± 0.519
4.75GluIle: 4.75 ± 1.279
4.019GluLys: 4.019 ± 0.728
5.48GluLeu: 5.48 ± 0.715
0.731GluMet: 0.731 ± 0.364
4.384GluAsn: 4.384 ± 0.907
1.279GluPro: 1.279 ± 0.42
1.279GluGln: 1.279 ± 0.591
2.192GluArg: 2.192 ± 0.927
3.106GluSer: 3.106 ± 1.086
2.923GluThr: 2.923 ± 0.623
4.567GluVal: 4.567 ± 1.21
0.548GluTrp: 0.548 ± 0.36
2.74GluTyr: 2.74 ± 0.964
0.0GluXaa: 0.0 ± 0.0
Phe
1.644PheAla: 1.644 ± 0.536
2.009PheCys: 2.009 ± 0.715
6.028PheAsp: 6.028 ± 0.906
3.836PheGlu: 3.836 ± 0.383
2.923PhePhe: 2.923 ± 0.675
4.019PheGly: 4.019 ± 0.589
0.548PheHis: 0.548 ± 0.264
4.202PheIle: 4.202 ± 1.039
6.394PheLys: 6.394 ± 0.725
4.75PheLeu: 4.75 ± 0.502
1.096PheMet: 1.096 ± 0.325
4.384PheAsn: 4.384 ± 0.615
0.913PhePro: 0.913 ± 0.299
1.279PheGln: 1.279 ± 0.531
2.558PheArg: 2.558 ± 0.577
6.577PheSer: 6.577 ± 1.638
3.836PheThr: 3.836 ± 0.537
4.932PheVal: 4.932 ± 1.39
0.183PheTrp: 0.183 ± 0.206
1.827PheTyr: 1.827 ± 0.532
0.0PheXaa: 0.0 ± 0.0
Gly
1.827GlyAla: 1.827 ± 0.773
1.096GlyCys: 1.096 ± 0.382
3.471GlyAsp: 3.471 ± 0.919
2.375GlyGlu: 2.375 ± 0.393
3.471GlyPhe: 3.471 ± 0.71
3.106GlyGly: 3.106 ± 1.004
1.279GlyHis: 1.279 ± 0.425
2.923GlyIle: 2.923 ± 0.769
4.202GlyLys: 4.202 ± 1.258
2.558GlyLeu: 2.558 ± 0.444
1.096GlyMet: 1.096 ± 0.496
2.923GlyAsn: 2.923 ± 0.455
1.096GlyPro: 1.096 ± 0.389
0.183GlyGln: 0.183 ± 0.128
2.009GlyArg: 2.009 ± 0.474
2.192GlySer: 2.192 ± 0.82
3.106GlyThr: 3.106 ± 1.029
4.384GlyVal: 4.384 ± 0.828
0.365GlyTrp: 0.365 ± 0.215
1.096GlyTyr: 1.096 ± 0.278
0.0GlyXaa: 0.0 ± 0.0
His
0.913HisAla: 0.913 ± 0.351
0.548HisCys: 0.548 ± 0.304
2.192HisAsp: 2.192 ± 0.524
0.548HisGlu: 0.548 ± 0.368
2.009HisPhe: 2.009 ± 0.628
1.461HisGly: 1.461 ± 0.356
0.365HisHis: 0.365 ± 0.27
2.009HisIle: 2.009 ± 0.486
1.096HisLys: 1.096 ± 0.386
3.288HisLeu: 3.288 ± 1.054
0.183HisMet: 0.183 ± 0.198
0.548HisAsn: 0.548 ± 0.383
1.096HisPro: 1.096 ± 0.634
0.548HisGln: 0.548 ± 0.288
0.183HisArg: 0.183 ± 0.128
0.913HisSer: 0.913 ± 0.355
0.365HisThr: 0.365 ± 0.182
0.731HisVal: 0.731 ± 0.231
0.183HisTrp: 0.183 ± 0.128
0.913HisTyr: 0.913 ± 0.465
0.0HisXaa: 0.0 ± 0.0
Ile
4.019IleAla: 4.019 ± 1.421
0.913IleCys: 0.913 ± 0.314
3.654IleAsp: 3.654 ± 1.089
4.202IleGlu: 4.202 ± 0.751
4.019IlePhe: 4.019 ± 0.665
2.923IleGly: 2.923 ± 1.086
0.913IleHis: 0.913 ± 0.299
4.019IleIle: 4.019 ± 0.762
4.75IleLys: 4.75 ± 1.361
7.673IleLeu: 7.673 ± 1.082
1.461IleMet: 1.461 ± 0.457
6.394IleAsn: 6.394 ± 1.209
3.471IlePro: 3.471 ± 0.529
1.644IleGln: 1.644 ± 0.483
4.202IleArg: 4.202 ± 1.274
7.673IleSer: 7.673 ± 1.447
2.923IleThr: 2.923 ± 1.0
4.019IleVal: 4.019 ± 0.764
0.183IleTrp: 0.183 ± 0.198
4.019IleTyr: 4.019 ± 0.665
0.0IleXaa: 0.0 ± 0.0
Lys
2.009LysAla: 2.009 ± 0.564
1.461LysCys: 1.461 ± 0.324
3.471LysAsp: 3.471 ± 1.057
3.106LysGlu: 3.106 ± 0.895
6.577LysPhe: 6.577 ± 1.378
2.192LysGly: 2.192 ± 0.739
1.827LysHis: 1.827 ± 0.704
5.846LysIle: 5.846 ± 0.886
4.75LysLys: 4.75 ± 1.083
8.951LysLeu: 8.951 ± 0.555
2.009LysMet: 2.009 ± 0.834
7.49LysAsn: 7.49 ± 0.853
3.654LysPro: 3.654 ± 0.515
2.009LysGln: 2.009 ± 0.456
2.923LysArg: 2.923 ± 0.245
5.846LysSer: 5.846 ± 1.026
4.019LysThr: 4.019 ± 1.225
4.567LysVal: 4.567 ± 0.933
0.365LysTrp: 0.365 ± 0.184
3.288LysTyr: 3.288 ± 0.593
0.0LysXaa: 0.0 ± 0.0
Leu
5.846LeuAla: 5.846 ± 0.792
1.279LeuCys: 1.279 ± 0.413
5.48LeuAsp: 5.48 ± 0.878
6.211LeuGlu: 6.211 ± 0.95
5.298LeuPhe: 5.298 ± 0.785
2.923LeuGly: 2.923 ± 0.92
1.827LeuHis: 1.827 ± 0.685
8.221LeuIle: 8.221 ± 1.189
8.769LeuLys: 8.769 ± 2.46
9.317LeuLeu: 9.317 ± 0.977
2.192LeuMet: 2.192 ± 0.853
7.307LeuAsn: 7.307 ± 1.333
3.106LeuPro: 3.106 ± 0.842
1.461LeuGln: 1.461 ± 0.414
5.115LeuArg: 5.115 ± 0.895
9.865LeuSer: 9.865 ± 1.403
6.759LeuThr: 6.759 ± 1.083
6.028LeuVal: 6.028 ± 1.311
0.0LeuTrp: 0.0 ± 0.0
2.923LeuTyr: 2.923 ± 1.03
0.0LeuXaa: 0.0 ± 0.0
Met
1.279MetAla: 1.279 ± 0.381
0.548MetCys: 0.548 ± 0.264
1.461MetAsp: 1.461 ± 0.691
0.913MetGlu: 0.913 ± 0.722
1.827MetPhe: 1.827 ± 0.766
0.731MetGly: 0.731 ± 0.667
1.279MetHis: 1.279 ± 0.449
0.913MetIle: 0.913 ± 0.411
2.009MetLys: 2.009 ± 0.79
2.009MetLeu: 2.009 ± 0.601
0.365MetMet: 0.365 ± 0.255
1.279MetAsn: 1.279 ± 0.376
0.365MetPro: 0.365 ± 0.212
0.183MetGln: 0.183 ± 0.128
1.461MetArg: 1.461 ± 0.355
1.279MetSer: 1.279 ± 0.284
1.096MetThr: 1.096 ± 0.4
1.279MetVal: 1.279 ± 0.304
0.0MetTrp: 0.0 ± 0.0
0.731MetTyr: 0.731 ± 0.367
0.0MetXaa: 0.0 ± 0.0
Asn
3.106AsnAla: 3.106 ± 0.816
1.279AsnCys: 1.279 ± 0.169
3.836AsnAsp: 3.836 ± 0.546
4.567AsnGlu: 4.567 ± 1.383
6.211AsnPhe: 6.211 ± 0.639
3.471AsnGly: 3.471 ± 0.909
1.461AsnHis: 1.461 ± 0.352
7.855AsnIle: 7.855 ± 1.421
6.028AsnLys: 6.028 ± 0.637
7.49AsnLeu: 7.49 ± 1.564
1.096AsnMet: 1.096 ± 0.54
4.567AsnAsn: 4.567 ± 1.091
2.375AsnPro: 2.375 ± 0.388
1.461AsnGln: 1.461 ± 0.476
1.644AsnArg: 1.644 ± 0.567
5.48AsnSer: 5.48 ± 1.124
1.644AsnThr: 1.644 ± 0.433
4.567AsnVal: 4.567 ± 0.628
0.183AsnTrp: 0.183 ± 0.206
2.923AsnTyr: 2.923 ± 0.903
0.0AsnXaa: 0.0 ± 0.0
Pro
1.827ProAla: 1.827 ± 0.381
0.183ProCys: 0.183 ± 0.239
1.461ProAsp: 1.461 ± 0.615
1.279ProGlu: 1.279 ± 0.381
1.279ProPhe: 1.279 ± 0.324
1.096ProGly: 1.096 ± 0.589
0.365ProHis: 0.365 ± 0.255
2.375ProIle: 2.375 ± 0.556
2.375ProLys: 2.375 ± 0.415
1.827ProLeu: 1.827 ± 0.592
0.731ProMet: 0.731 ± 0.231
2.558ProAsn: 2.558 ± 0.601
0.183ProPro: 0.183 ± 0.128
0.548ProGln: 0.548 ± 0.262
1.461ProArg: 1.461 ± 0.33
3.106ProSer: 3.106 ± 0.511
2.558ProThr: 2.558 ± 0.695
3.654ProVal: 3.654 ± 0.596
0.0ProTrp: 0.0 ± 0.0
2.009ProTyr: 2.009 ± 0.585
0.0ProXaa: 0.0 ± 0.0
Gln
2.009GlnAla: 2.009 ± 0.786
0.183GlnCys: 0.183 ± 0.128
0.913GlnAsp: 0.913 ± 0.254
0.731GlnGlu: 0.731 ± 0.335
1.279GlnPhe: 1.279 ± 0.437
0.548GlnGly: 0.548 ± 0.256
0.365GlnHis: 0.365 ± 0.255
0.913GlnIle: 0.913 ± 0.404
1.096GlnLys: 1.096 ± 0.644
3.836GlnLeu: 3.836 ± 0.504
0.548GlnMet: 0.548 ± 0.238
0.913GlnAsn: 0.913 ± 0.283
0.548GlnPro: 0.548 ± 0.408
0.731GlnGln: 0.731 ± 0.349
0.913GlnArg: 0.913 ± 0.336
2.923GlnSer: 2.923 ± 0.854
1.827GlnThr: 1.827 ± 0.369
1.644GlnVal: 1.644 ± 0.659
0.0GlnTrp: 0.0 ± 0.0
1.096GlnTyr: 1.096 ± 0.281
0.0GlnXaa: 0.0 ± 0.0
Arg
1.461ArgAla: 1.461 ± 0.431
0.913ArgCys: 0.913 ± 0.282
2.192ArgAsp: 2.192 ± 0.831
1.644ArgGlu: 1.644 ± 0.344
3.106ArgPhe: 3.106 ± 0.764
2.009ArgGly: 2.009 ± 0.649
1.461ArgHis: 1.461 ± 0.829
3.654ArgIle: 3.654 ± 1.369
3.836ArgLys: 3.836 ± 0.428
4.932ArgLeu: 4.932 ± 0.802
0.548ArgMet: 0.548 ± 0.247
3.836ArgAsn: 3.836 ± 0.649
1.461ArgPro: 1.461 ± 0.892
2.009ArgGln: 2.009 ± 0.85
2.375ArgArg: 2.375 ± 0.726
3.654ArgSer: 3.654 ± 0.757
1.461ArgThr: 1.461 ± 0.53
2.009ArgVal: 2.009 ± 0.594
0.183ArgTrp: 0.183 ± 0.215
0.548ArgTyr: 0.548 ± 0.618
0.0ArgXaa: 0.0 ± 0.0
Ser
4.384SerAla: 4.384 ± 0.708
1.279SerCys: 1.279 ± 0.397
7.49SerAsp: 7.49 ± 0.95
4.75SerGlu: 4.75 ± 0.588
3.106SerPhe: 3.106 ± 0.52
5.115SerGly: 5.115 ± 1.018
1.644SerHis: 1.644 ± 0.394
4.202SerIle: 4.202 ± 0.829
6.211SerLys: 6.211 ± 1.284
7.49SerLeu: 7.49 ± 2.096
1.461SerMet: 1.461 ± 0.411
6.577SerAsn: 6.577 ± 0.884
3.288SerPro: 3.288 ± 1.13
2.009SerGln: 2.009 ± 0.555
4.019SerArg: 4.019 ± 0.774
6.028SerSer: 6.028 ± 0.81
4.932SerThr: 4.932 ± 1.178
5.663SerVal: 5.663 ± 1.626
0.731SerTrp: 0.731 ± 0.338
3.654SerTyr: 3.654 ± 0.713
0.0SerXaa: 0.0 ± 0.0
Thr
2.923ThrAla: 2.923 ± 1.017
0.913ThrCys: 0.913 ± 0.411
3.471ThrAsp: 3.471 ± 1.261
2.375ThrGlu: 2.375 ± 0.506
3.288ThrPhe: 3.288 ± 0.644
2.009ThrGly: 2.009 ± 0.813
0.365ThrHis: 0.365 ± 0.255
3.471ThrIle: 3.471 ± 0.473
3.654ThrLys: 3.654 ± 0.489
6.394ThrLeu: 6.394 ± 1.239
1.279ThrMet: 1.279 ± 0.462
2.375ThrAsn: 2.375 ± 0.709
2.375ThrPro: 2.375 ± 0.567
1.279ThrGln: 1.279 ± 0.431
1.644ThrArg: 1.644 ± 0.51
4.75ThrSer: 4.75 ± 0.955
3.836ThrThr: 3.836 ± 0.735
4.019ThrVal: 4.019 ± 1.182
0.548ThrTrp: 0.548 ± 0.434
1.096ThrTyr: 1.096 ± 0.414
0.0ThrXaa: 0.0 ± 0.0
Val
2.192ValAla: 2.192 ± 0.449
2.375ValCys: 2.375 ± 0.939
6.211ValAsp: 6.211 ± 1.323
3.471ValGlu: 3.471 ± 1.009
4.202ValPhe: 4.202 ± 0.372
4.75ValGly: 4.75 ± 1.06
1.461ValHis: 1.461 ± 0.465
4.202ValIle: 4.202 ± 0.933
4.75ValLys: 4.75 ± 0.904
5.298ValLeu: 5.298 ± 0.581
1.279ValMet: 1.279 ± 0.478
6.028ValAsn: 6.028 ± 1.083
2.009ValPro: 2.009 ± 0.696
2.192ValGln: 2.192 ± 0.484
2.558ValArg: 2.558 ± 0.629
6.577ValSer: 6.577 ± 1.263
2.009ValThr: 2.009 ± 0.456
3.836ValVal: 3.836 ± 0.679
0.548ValTrp: 0.548 ± 0.54
1.461ValTyr: 1.461 ± 0.399
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.183TrpCys: 0.183 ± 0.128
0.365TrpAsp: 0.365 ± 0.215
0.183TrpGlu: 0.183 ± 0.22
0.0TrpPhe: 0.0 ± 0.0
0.365TrpGly: 0.365 ± 0.327
0.0TrpHis: 0.0 ± 0.0
0.731TrpIle: 0.731 ± 0.365
0.365TrpLys: 0.365 ± 0.342
0.913TrpLeu: 0.913 ± 0.399
0.0TrpMet: 0.0 ± 0.0
0.183TrpAsn: 0.183 ± 0.206
0.0TrpPro: 0.0 ± 0.0
0.183TrpGln: 0.183 ± 0.198
0.183TrpArg: 0.183 ± 0.206
0.0TrpSer: 0.0 ± 0.0
0.731TrpThr: 0.731 ± 0.231
0.548TrpVal: 0.548 ± 0.311
0.0TrpTrp: 0.0 ± 0.0
0.365TrpTyr: 0.365 ± 0.27
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.827TyrAla: 1.827 ± 0.327
1.461TyrCys: 1.461 ± 0.425
2.74TyrAsp: 2.74 ± 0.454
1.827TyrGlu: 1.827 ± 0.554
2.923TyrPhe: 2.923 ± 1.358
1.096TyrGly: 1.096 ± 0.256
0.731TyrHis: 0.731 ± 0.335
2.192TyrIle: 2.192 ± 0.721
0.913TyrLys: 0.913 ± 0.229
3.106TyrLeu: 3.106 ± 0.511
1.096TyrMet: 1.096 ± 0.424
2.74TyrAsn: 2.74 ± 0.595
0.913TyrPro: 0.913 ± 0.282
0.913TyrGln: 0.913 ± 0.452
1.644TyrArg: 1.644 ± 0.3
4.202TyrSer: 4.202 ± 0.702
1.461TyrThr: 1.461 ± 0.31
3.288TyrVal: 3.288 ± 0.565
0.548TyrTrp: 0.548 ± 0.442
2.375TyrTyr: 2.375 ± 0.573
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (5475 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski