Amino acid dipepetide frequency for Candidatus Terasakiella magnetica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.591AlaAla: 8.591 ± 0.159	1.091AlaCys: 1.091 ± 0.038	5.014AlaAsp: 5.014 ± 0.128	5.884AlaGlu: 5.884 ± 0.084	3.667AlaPhe: 3.667 ± 0.065	6.499AlaGly: 6.499 ± 0.103	1.997AlaHis: 1.997 ± 0.048	5.43AlaIle: 5.43 ± 0.07	5.428AlaLys: 5.428 ± 0.079	9.362AlaLeu: 9.362 ± 0.105	2.788AlaMet: 2.788 ± 0.065	3.137AlaAsn: 3.137 ± 0.093	3.354AlaPro: 3.354 ± 0.078	4.091AlaGln: 4.091 ± 0.072	4.428AlaArg: 4.428 ± 0.08	5.281AlaSer: 5.281 ± 0.096	4.436AlaThr: 4.436 ± 0.104	6.001AlaVal: 6.001 ± 0.1	0.897AlaTrp: 0.897 ± 0.028	2.381AlaTyr: 2.381 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.987CysAla: 0.987 ± 0.04	0.15CysCys: 0.15 ± 0.013	0.753CysAsp: 0.753 ± 0.031	0.751CysGlu: 0.751 ± 0.03	0.423CysPhe: 0.423 ± 0.023	0.944CysGly: 0.944 ± 0.037	0.342CysHis: 0.342 ± 0.022	0.549CysIle: 0.549 ± 0.026	0.468CysLys: 0.468 ± 0.022	1.03CysLeu: 1.03 ± 0.038	0.208CysMet: 0.208 ± 0.016	0.335CysAsn: 0.335 ± 0.021	0.503CysPro: 0.503 ± 0.024	0.37CysGln: 0.37 ± 0.018	0.491CysArg: 0.491 ± 0.023	0.642CysSer: 0.642 ± 0.032	0.536CysThr: 0.536 ± 0.022	0.783CysVal: 0.783 ± 0.034	0.11CysTrp: 0.11 ± 0.009	0.253CysTyr: 0.253 ± 0.016	0.001CysXaa: 0.001 ± 0.001
Asp	4.927AspAla: 4.927 ± 0.131	0.629AspCys: 0.629 ± 0.027	3.843AspAsp: 3.843 ± 0.104	4.885AspGlu: 4.885 ± 0.076	2.713AspPhe: 2.713 ± 0.06	4.972AspGly: 4.972 ± 0.245	1.576AspHis: 1.576 ± 0.041	4.243AspIle: 4.243 ± 0.069	3.188AspLys: 3.188 ± 0.064	6.068AspLeu: 6.068 ± 0.078	1.876AspMet: 1.876 ± 0.047	2.084AspAsn: 2.084 ± 0.069	2.414AspPro: 2.414 ± 0.053	2.266AspGln: 2.266 ± 0.038	2.683AspArg: 2.683 ± 0.059	2.597AspSer: 2.597 ± 0.088	2.979AspThr: 2.979 ± 0.13	4.657AspVal: 4.657 ± 0.092	0.869AspTrp: 0.869 ± 0.028	1.93AspTyr: 1.93 ± 0.059	0.0AspXaa: 0.0 ± 0.0
Glu	6.689GluAla: 6.689 ± 0.087	0.538GluCys: 0.538 ± 0.027	4.035GluAsp: 4.035 ± 0.063	5.651GluGlu: 5.651 ± 0.116	2.388GluPhe: 2.388 ± 0.045	4.771GluGly: 4.771 ± 0.081	1.513GluHis: 1.513 ± 0.043	4.818GluIle: 4.818 ± 0.071	4.727GluLys: 4.727 ± 0.089	6.584GluLeu: 6.584 ± 0.106	2.176GluMet: 2.176 ± 0.052	3.105GluAsn: 3.105 ± 0.053	2.103GluPro: 2.103 ± 0.073	2.684GluGln: 2.684 ± 0.058	4.008GluArg: 4.008 ± 0.083	2.877GluSer: 2.877 ± 0.054	4.134GluThr: 4.134 ± 0.072	4.517GluVal: 4.517 ± 0.071	0.694GluTrp: 0.694 ± 0.025	1.538GluTyr: 1.538 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	3.536PheAla: 3.536 ± 0.061	0.514PheCys: 0.514 ± 0.025	2.98PheAsp: 2.98 ± 0.055	2.831PheGlu: 2.831 ± 0.055	1.815PhePhe: 1.815 ± 0.047	3.158PheGly: 3.158 ± 0.058	0.803PheHis: 0.803 ± 0.028	2.551PheIle: 2.551 ± 0.054	2.26PheLys: 2.26 ± 0.057	3.808PheLeu: 3.808 ± 0.083	1.123PheMet: 1.123 ± 0.029	1.684PheAsn: 1.684 ± 0.037	1.385PhePro: 1.385 ± 0.045	1.207PheGln: 1.207 ± 0.031	1.548PheArg: 1.548 ± 0.043	2.845PheSer: 2.845 ± 0.054	2.152PheThr: 2.152 ± 0.055	2.611PheVal: 2.611 ± 0.051	0.526PheTrp: 0.526 ± 0.022	1.195PheTyr: 1.195 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	6.106GlyAla: 6.106 ± 0.089	0.884GlyCys: 0.884 ± 0.034	4.406GlyAsp: 4.406 ± 0.143	4.968GlyGlu: 4.968 ± 0.08	3.36GlyPhe: 3.36 ± 0.053	5.595GlyGly: 5.595 ± 0.136	1.772GlyHis: 1.772 ± 0.041	4.397GlyIle: 4.397 ± 0.073	4.333GlyLys: 4.333 ± 0.074	7.453GlyLeu: 7.453 ± 0.126	2.201GlyMet: 2.201 ± 0.052	2.552GlyAsn: 2.552 ± 0.112	2.242GlyPro: 2.242 ± 0.048	2.764GlyGln: 2.764 ± 0.056	3.696GlyArg: 3.696 ± 0.064	4.227GlySer: 4.227 ± 0.131	4.007GlyThr: 4.007 ± 0.166	5.594GlyVal: 5.594 ± 0.082	0.922GlyTrp: 0.922 ± 0.028	2.361GlyTyr: 2.361 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.807HisAla: 1.807 ± 0.046	0.304HisCys: 0.304 ± 0.016	1.31HisAsp: 1.31 ± 0.039	1.431HisGlu: 1.431 ± 0.038	0.992HisPhe: 0.992 ± 0.033	1.681HisGly: 1.681 ± 0.037	0.68HisHis: 0.68 ± 0.03	1.485HisIle: 1.485 ± 0.04	1.184HisLys: 1.184 ± 0.034	2.214HisLeu: 2.214 ± 0.054	0.693HisMet: 0.693 ± 0.029	0.839HisAsn: 0.839 ± 0.028	1.2HisPro: 1.2 ± 0.041	0.797HisGln: 0.797 ± 0.029	1.031HisArg: 1.031 ± 0.035	1.255HisSer: 1.255 ± 0.035	0.975HisThr: 0.975 ± 0.027	1.461HisVal: 1.461 ± 0.036	0.321HisTrp: 0.321 ± 0.019	0.716HisTyr: 0.716 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.952IleAla: 5.952 ± 0.082	0.753IleCys: 0.753 ± 0.028	4.083IleAsp: 4.083 ± 0.067	4.81IleGlu: 4.81 ± 0.071	2.241IlePhe: 2.241 ± 0.052	4.725IleGly: 4.725 ± 0.069	1.252IleHis: 1.252 ± 0.034	3.728IleIle: 3.728 ± 0.065	3.452IleLys: 3.452 ± 0.067	5.431IleLeu: 5.431 ± 0.1	1.516IleMet: 1.516 ± 0.042	2.521IleAsn: 2.521 ± 0.052	2.512IlePro: 2.512 ± 0.061	1.924IleGln: 1.924 ± 0.048	2.82IleArg: 2.82 ± 0.056	4.407IleSer: 4.407 ± 0.074	3.52IleThr: 3.52 ± 0.081	4.105IleVal: 4.105 ± 0.059	0.64IleTrp: 0.64 ± 0.027	1.506IleTyr: 1.506 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	5.81LysAla: 5.81 ± 0.095	0.409LysCys: 0.409 ± 0.02	3.551LysAsp: 3.551 ± 0.062	4.328LysGlu: 4.328 ± 0.091	1.756LysPhe: 1.756 ± 0.041	4.131LysGly: 4.131 ± 0.085	1.192LysHis: 1.192 ± 0.036	3.494LysIle: 3.494 ± 0.056	4.26LysLys: 4.26 ± 0.108	5.211LysLeu: 5.211 ± 0.082	1.679LysMet: 1.679 ± 0.046	2.501LysAsn: 2.501 ± 0.061	2.64LysPro: 2.64 ± 0.077	2.116LysGln: 2.116 ± 0.058	3.308LysArg: 3.308 ± 0.082	3.369LysSer: 3.369 ± 0.063	3.42LysThr: 3.42 ± 0.058	3.747LysVal: 3.747 ± 0.07	0.641LysTrp: 0.641 ± 0.027	1.405LysTyr: 1.405 ± 0.04	0.001LysXaa: 0.001 ± 0.001
Leu	8.76LeuAla: 8.76 ± 0.092	1.132LeuCys: 1.132 ± 0.046	5.811LeuAsp: 5.811 ± 0.08	6.518LeuGlu: 6.518 ± 0.094	3.941LeuPhe: 3.941 ± 0.085	6.855LeuGly: 6.855 ± 0.104	2.018LeuHis: 2.018 ± 0.048	5.696LeuIle: 5.696 ± 0.089	6.118LeuLys: 6.118 ± 0.122	8.706LeuLeu: 8.706 ± 0.152	2.591LeuMet: 2.591 ± 0.059	4.064LeuAsn: 4.064 ± 0.06	4.316LeuPro: 4.316 ± 0.078	3.087LeuGln: 3.087 ± 0.063	4.791LeuArg: 4.791 ± 0.096	7.615LeuSer: 7.615 ± 0.086	5.042LeuThr: 5.042 ± 0.078	6.27LeuVal: 6.27 ± 0.099	0.951LeuTrp: 0.951 ± 0.032	2.315LeuTyr: 2.315 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.926MetAla: 2.926 ± 0.066	0.236MetCys: 0.236 ± 0.015	1.674MetAsp: 1.674 ± 0.041	1.819MetGlu: 1.819 ± 0.047	0.899MetPhe: 0.899 ± 0.034	2.291MetGly: 2.291 ± 0.055	0.516MetHis: 0.516 ± 0.022	1.591MetIle: 1.591 ± 0.04	1.74MetLys: 1.74 ± 0.051	2.334MetLeu: 2.334 ± 0.058	0.902MetMet: 0.902 ± 0.032	1.1MetAsn: 1.1 ± 0.039	1.323MetPro: 1.323 ± 0.043	0.921MetGln: 0.921 ± 0.029	1.6MetArg: 1.6 ± 0.048	2.059MetSer: 2.059 ± 0.047	1.761MetThr: 1.761 ± 0.042	2.043MetVal: 2.043 ± 0.045	0.23MetTrp: 0.23 ± 0.015	0.432MetTyr: 0.432 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.505AsnAla: 3.505 ± 0.077	0.408AsnCys: 0.408 ± 0.022	2.44AsnAsp: 2.44 ± 0.116	2.46AsnGlu: 2.46 ± 0.053	1.396AsnPhe: 1.396 ± 0.039	3.077AsnGly: 3.077 ± 0.127	0.84AsnHis: 0.84 ± 0.026	2.609AsnIle: 2.609 ± 0.048	2.145AsnLys: 2.145 ± 0.056	3.733AsnLeu: 3.733 ± 0.059	1.07AsnMet: 1.07 ± 0.032	1.482AsnAsn: 1.482 ± 0.047	2.026AsnPro: 2.026 ± 0.044	1.425AsnGln: 1.425 ± 0.042	1.872AsnArg: 1.872 ± 0.05	2.043AsnSer: 2.043 ± 0.055	1.899AsnThr: 1.899 ± 0.061	2.628AsnVal: 2.628 ± 0.058	0.534AsnTrp: 0.534 ± 0.021	1.042AsnTyr: 1.042 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	3.292ProAla: 3.292 ± 0.073	0.395ProCys: 0.395 ± 0.023	2.738ProAsp: 2.738 ± 0.051	3.332ProGlu: 3.332 ± 0.076	1.857ProPhe: 1.857 ± 0.049	2.361ProGly: 2.361 ± 0.054	0.963ProHis: 0.963 ± 0.03	2.376ProIle: 2.376 ± 0.055	2.459ProLys: 2.459 ± 0.07	3.766ProLeu: 3.766 ± 0.067	1.049ProMet: 1.049 ± 0.037	1.58ProAsn: 1.58 ± 0.037	1.447ProPro: 1.447 ± 0.065	1.517ProGln: 1.517 ± 0.046	1.561ProArg: 1.561 ± 0.044	2.429ProSer: 2.429 ± 0.047	2.053ProThr: 2.053 ± 0.05	3.14ProVal: 3.14 ± 0.061	0.497ProTrp: 0.497 ± 0.023	1.184ProTyr: 1.184 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.951GlnAla: 3.951 ± 0.067	0.309GlnCys: 0.309 ± 0.018	2.136GlnAsp: 2.136 ± 0.042	2.478GlnGlu: 2.478 ± 0.059	1.226GlnPhe: 1.226 ± 0.035	2.596GlnGly: 2.596 ± 0.051	0.739GlnHis: 0.739 ± 0.026	2.235GlnIle: 2.235 ± 0.049	2.43GlnLys: 2.43 ± 0.062	3.193GlnLeu: 3.193 ± 0.051	1.069GlnMet: 1.069 ± 0.032	1.537GlnAsn: 1.537 ± 0.038	1.375GlnPro: 1.375 ± 0.042	1.47GlnGln: 1.47 ± 0.038	1.833GlnArg: 1.833 ± 0.043	2.356GlnSer: 2.356 ± 0.057	2.133GlnThr: 2.133 ± 0.057	2.498GlnVal: 2.498 ± 0.051	0.442GlnTrp: 0.442 ± 0.021	0.921GlnTyr: 0.921 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	4.01ArgAla: 4.01 ± 0.073	0.457ArgCys: 0.457 ± 0.019	2.982ArgAsp: 2.982 ± 0.059	3.36ArgGlu: 3.36 ± 0.066	2.211ArgPhe: 2.211 ± 0.046	2.909ArgGly: 2.909 ± 0.055	1.194ArgHis: 1.194 ± 0.041	3.208ArgIle: 3.208 ± 0.065	2.942ArgLys: 2.942 ± 0.068	5.309ArgLeu: 5.309 ± 0.105	1.501ArgMet: 1.501 ± 0.046	1.856ArgAsn: 1.856 ± 0.051	1.888ArgPro: 1.888 ± 0.053	1.877ArgGln: 1.877 ± 0.049	2.812ArgArg: 2.812 ± 0.083	2.616ArgSer: 2.616 ± 0.062	2.44ArgThr: 2.44 ± 0.057	3.326ArgVal: 3.326 ± 0.071	0.566ArgTrp: 0.566 ± 0.027	1.465ArgTyr: 1.465 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	5.136SerAla: 5.136 ± 0.11	0.642SerCys: 0.642 ± 0.027	3.751SerAsp: 3.751 ± 0.12	3.768SerGlu: 3.768 ± 0.071	2.893SerPhe: 2.893 ± 0.057	4.867SerGly: 4.867 ± 0.111	1.404SerHis: 1.404 ± 0.038	3.629SerIle: 3.629 ± 0.057	3.218SerLys: 3.218 ± 0.059	6.409SerLeu: 6.409 ± 0.088	1.712SerMet: 1.712 ± 0.044	2.296SerAsn: 2.296 ± 0.063	2.382SerPro: 2.382 ± 0.05	2.415SerGln: 2.415 ± 0.049	2.626SerArg: 2.626 ± 0.063	3.856SerSer: 3.856 ± 0.094	3.041SerThr: 3.041 ± 0.081	4.222SerVal: 4.222 ± 0.066	0.74SerTrp: 0.74 ± 0.027	1.872SerTyr: 1.872 ± 0.066	0.0SerXaa: 0.0 ± 0.0
Thr	4.586ThrAla: 4.586 ± 0.139	0.519ThrCys: 0.519 ± 0.023	3.096ThrAsp: 3.096 ± 0.11	2.852ThrGlu: 2.852 ± 0.06	2.309ThrPhe: 2.309 ± 0.061	4.493ThrGly: 4.493 ± 0.106	1.237ThrHis: 1.237 ± 0.032	3.365ThrIle: 3.365 ± 0.079	2.671ThrLys: 2.671 ± 0.05	5.478ThrLeu: 5.478 ± 0.078	1.282ThrMet: 1.282 ± 0.037	1.871ThrAsn: 1.871 ± 0.081	2.775ThrPro: 2.775 ± 0.054	2.095ThrGln: 2.095 ± 0.045	2.273ThrArg: 2.273 ± 0.05	3.212ThrSer: 3.212 ± 0.076	2.949ThrThr: 2.949 ± 0.099	3.894ThrVal: 3.894 ± 0.109	0.58ThrTrp: 0.58 ± 0.032	1.605ThrTyr: 1.605 ± 0.069	0.0ThrXaa: 0.0 ± 0.0
Val	6.134ValAla: 6.134 ± 0.084	0.794ValCys: 0.794 ± 0.029	4.273ValAsp: 4.273 ± 0.071	5.028ValGlu: 5.028 ± 0.089	2.775ValPhe: 2.775 ± 0.054	4.859ValGly: 4.859 ± 0.078	1.358ValHis: 1.358 ± 0.036	4.451ValIle: 4.451 ± 0.073	3.821ValLys: 3.821 ± 0.066	6.607ValLeu: 6.607 ± 0.087	1.966ValMet: 1.966 ± 0.042	2.595ValAsn: 2.595 ± 0.08	2.554ValPro: 2.554 ± 0.048	2.28ValGln: 2.28 ± 0.049	3.474ValArg: 3.474 ± 0.077	4.837ValSer: 4.837 ± 0.083	3.846ValThr: 3.846 ± 0.114	5.127ValVal: 5.127 ± 0.087	0.754ValTrp: 0.754 ± 0.032	1.661ValTyr: 1.661 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	0.935TrpAla: 0.935 ± 0.03	0.135TrpCys: 0.135 ± 0.013	0.692TrpAsp: 0.692 ± 0.032	0.669TrpGlu: 0.669 ± 0.027	0.49TrpPhe: 0.49 ± 0.021	0.791TrpGly: 0.791 ± 0.029	0.297TrpHis: 0.297 ± 0.014	0.597TrpIle: 0.597 ± 0.028	0.687TrpLys: 0.687 ± 0.025	1.208TrpLeu: 1.208 ± 0.04	0.328TrpMet: 0.328 ± 0.015	0.483TrpAsn: 0.483 ± 0.026	0.435TrpPro: 0.435 ± 0.021	0.542TrpGln: 0.542 ± 0.022	0.641TrpArg: 0.641 ± 0.026	0.69TrpSer: 0.69 ± 0.027	0.55TrpThr: 0.55 ± 0.031	0.81TrpVal: 0.81 ± 0.026	0.153TrpTrp: 0.153 ± 0.013	0.305TrpTyr: 0.305 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.116TyrAla: 2.116 ± 0.045	0.329TyrCys: 0.329 ± 0.021	1.831TyrAsp: 1.831 ± 0.064	1.728TyrGlu: 1.728 ± 0.044	1.18TyrPhe: 1.18 ± 0.034	2.264TyrGly: 2.264 ± 0.05	0.685TyrHis: 0.685 ± 0.024	1.448TyrIle: 1.448 ± 0.043	1.435TyrLys: 1.435 ± 0.042	2.691TyrLeu: 2.691 ± 0.054	0.668TyrMet: 0.668 ± 0.028	1.013TyrAsn: 1.013 ± 0.039	1.119TyrPro: 1.119 ± 0.033	1.078TyrGln: 1.078 ± 0.03	1.435TyrArg: 1.435 ± 0.037	1.663TyrSer: 1.663 ± 0.052	1.27TyrThr: 1.27 ± 0.058	1.763TyrVal: 1.763 ± 0.046	0.37TyrTrp: 0.37 ± 0.02	0.826TyrTyr: 0.826 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.001XaaMet: 0.001 ± 0.001	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3572 proteins (1122897 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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